• Phosphatome.Net

Gene F40G12.10

F40G12.10
Species: C.elegans
Alias: F40G12.10
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: N_Nematode_5
Protein domain

Protein domains of F40G12.10.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase F40G12.10.AA Subfamily.N23.PD 38-399 19 9.3e-13 38.8 In-house 14-348 (350) Show / Hide 
Range on Protein: 38-399
Range on HMM: 14-348/350
Sequence Identity: 19% (66 aa)

SRRPQKSRSNSKQKATGPTSALPTDPKSKIDttfmeitaKGFKSKKGKKLKKKKEETSASKSPS-TltlgkaeshmdfsgnvknvekgvkvwielleKMD
|| | .  .   .  | |    |  |.. .         .  ....|.. ..... ....|  | .. .|.. . | .    |..|     .  ..    
srppsrptaskpeyltrppeinpqgpvetlw--------seledyqgqeaiaadqsiasakrmsnk-------------------------------nrq

FRKTMEPEFKPIDTMKADLEKCQAFKKNIDFSQSENVELYDTNRVKGG-----GEADFFYHGSTLTIPSVTTKSTILAQLAIvdsPQSLESFWIMVASQK
 |... .  | ||||       |. | ..  . |   . .. . | .|  |   ...|  || || .|. . . .|. |.| .|. . .|.|.|    . 
fnpdllpyhlqpttitavpqprhlqtegsGqqqgtpdsrhdpnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPi---astlaDFWlmvweqq

IQRLFILLGEEELDKPTLSEYFPEDF---KEFKTIRVNNrKTVPKTEEQANTQLYYEVVPKDCAEAPFAMieICDFWPDAKIPTMGYNRI--AATAASVF
|  .||   | . ..|.  . .|  .  . .       .      |...|    . .     . ...    ..... ..   |. .   | ||.| | | 
ssviVmltkevegnklkcdqYwPidegetnlfgdlrvsl-kslrssegwiervlhlqhndvstvrlvchl--htttWseiGvPksPedllaflgevetay

----ESDIDCDASCAIVSN--YGAGRAGSFFVAVLAIEKLQAGEA-PNIKEIALSVRSQRPAAIETLSQYMFTYVIALTY
. ||..|.||.  .|| ..   .| ||   ...  .. ..| . |..                                 
aqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagngiiniprvvrrlrqqRkymvqkkvilkklyeavlea
Phosphatase F40G12.10.AA Subfamily.N_Nematode_5.PD 141-400 33 2.4e-77 250.6 In-house 2-257 (258) Show / Hide 
Range on Protein: 141-400
Range on HMM: 2-257/258
Sequence Identity: 33% (87 aa)

MEPEFKPIDTMKADLEKCQAFKKNIDFSQSENVELYDTNRVKGGGEADFFYHGSTLTIPSVTTkSTILAQLAIVDSPqslESFWIMVASQKIQRLFILLG
.. ||. ....|.. |.|.||.||.. ..|..|...|..|||.. |.| ... |......... ..||.||  .|.    |.||||...||.....|...
lktefeklaslkpnketckafeknlkknrskdvkilDetrVkltdeddsYinaskiklddlek-kliltQlPlpdte---edFWrmvyqekitsvvllve

EEELDKPTLsEYFP---EDFKEFKTIRVNNRKTVPKTEEQanTQLYYEVVPKDCAEAPFAMIEICDFWPDAKIPTMGYNRIAATAASVFESDIDCDASCA
|||....  ..||   .|....... .||||.  |..|.  .....||.|..|.|. ||... .. |.. |.|.. .. |......|.... ...|.. .
deelketav-sffpletgdylnlgkmfinnrkvevkedek--keytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgknapvv

IVSNYGAGRAGSFFVAVLAIEKLQAGEAPNIKEIALSVRSQRPAAIETLSQYMFTYVIALTYG
||..|.||||.|... .|||.|..|..|||.||  ..||||| |.|.|.||...| ..|.|  
vvsdlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaavldyi
Phosphatase F40G12.10.AA Y_phosphatase 164-398 19 7e-34 120.29 Pfam 1-243 (243) Show / Hide 
Range on Protein: 164-398
Range on HMM: 1-243/243
Sequence Identity: 19% (48 aa)

NIDFSQSENVELYDTNRVKGG----GEADFFYHGSTLTIPSVTTKSTILAQLAIVDSPQSLESFWIMVASQKIQRLFILLGEEELDKP---TLSEYFPE-
| .  .. ..  || .||| .    .| ..... .  ..|.   |  |..|        ..| || ||  ||. .  . | ... ..    | ..|.|. 
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMP---HTIEDFWRMVWQQKC-TCIVMLCNCMEMGRDEKTCHQYWPDN

---DFKEFKTIRVNNRKTVPKTEEQANTQLYYEVVPKD-CAEAPFAMIEICDFWPDAKIPTMGYNRIAATAASVFESDIDCDAS---CAIVSNYGAGRAG
   .....  ..|.....    ..  ..        .| . |  . .   .  ||| ..| .. . .      | ..  ..|..     ...  |.||.|
KEGQPMTYGDFQVTCVSEEH--CPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTG

SFFVAVLAIEKLQAGEAPNIKEIALSVRSQRPAAIETLSQYMFTYVIALT
 | ..  ......... ..|..|  ..|.||| ...|..||.| | . | 
TFCAIDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE
Phosphatase F40G12.10.AA PTPc 140-401 17 2.3e-32 114.74 SMART 1-308 (308) Show / Hide 
Range on Protein: 140-401
Range on HMM: 1-308/308
Sequence Identity: 17% (54 aa)

TMEPEFKPIDTMKADLE----------KCQAFKKNI--DFSQSE-NVELYDTNRVKGGG--------EADFFYHGSTLTIPSVTTKSTILAQLAIVDSPQ
  . ||. ...|. ...          .| ....|.  |  ..  ..  || .|||           | ... . .   ..   .|. |..|      | 
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY-WRPKRYICTQGPL---PH

SLESFWIMVASQKIQRLFILLGEEEL--------DKPTLSEYFPEDFKEFKTIRVNNRKTVPKTEEQANTQLYYEVVPKD------CAEAPFAMIEICDF
 .| || ||  ||..    |  ..|         ..     |.|....... |.|...... . ..   ......    .      | |  . .   .  
TIEDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDEPMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTN

WPDAKIP-TMG-----YNRIAATAA-------------SVFESDIDCDASCAIVSNYGAGRAGSFFVAVLAIEKLQAGEAPNIKEIALSVRSQRPAAIET
||| ..| ..      .... .. .             | . .. ....   ... .|.||.|.| ..  .......   ..|..|  ..|.||| ...|
WPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNS-KYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQT

LSQYMFTYVIALTYGL
. ||.| | ..| | .
EEQYIFCYRCILEYIK
Phosphatase F40G12.10.AA Subfamily.R_Anemone_1.PD 144-398 21 2.3e-19 61.0 In-house 5-255 (258) Show / Hide 
Range on Protein: 144-398
Range on HMM: 5-255/258
Sequence Identity: 21% (56 aa)

EFKPIDTMKADLEKCQAFKKNIDFSQSENVELYDTNRVKG-----GGEADFFyHGSTLTIPSVTtKSTILAQLAIvdsPQSLESFWIMVASQKIQRLFIL
||. ....|..  ..   ..| .  . ...  .|  ||         |.|.    | |   . | .. |..| ..   ....| || ||  .||. . .|
efqrlkeikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYi-nasylrasdkt-rafiatqapl---eetvedFWrmvwqekigviVmL

LGEEELDKPTLSEYFPEDFKEFKTIRVNNRktvpKTEEQANTQLYYEVVPKDCAEAPfAMIEICD--FWPDAKIPTMGYNrIAATAASVFESDIDCDASC
 . .| .| . ..|.|.  ... ..||. |    |.|..|.  .   |. |.  .    ..   .   |||  .|.     . .   .| .|.   ... 
tnliegekkkchqYwPdstekygelrvslr----kkevfadyiirtlvlskkketee-revvqyhftvWpdkgvPqyata-vLglrrkvqksslagarpv

AIVSNYGAGRAGSFFVAVLAIEKLQAGEAPNIKEIALSVRSQRPAAIETLSQYMFTYVIALT
 .    | ||.| | |    .|.... .  .| ..  ..|..|| ...| .||.|. . |  
vvhCsaGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavle
Phosphatase F40G12.10.AA Subfamily.N13.PD 143-398 25 2.2e-18 57.6 In-house 4-256 (259) Show / Hide 
Range on Protein: 143-398
Range on HMM: 4-256/259
Sequence Identity: 25% (65 aa)

PEFKPIDTMKADLeKCQAFKK--NIDFSQSENVELYDTNRVKGGGEADfFYHGSTLTIPSvtTKSTILAQLAIVDSPQSLESFWIMVASQKIQRLFILLG
||| .  .|. . .|.  ||  | |  .  ||  ||  ||| |.|.  .   | . .|    . .  . ..    |.. . || ||  || .. ..  | 
eefkelrelkpld-tcevgkkkenkdknryrnvlPydetrvklgdegg-yinaslikvpv--gedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtl

EEELDKPTLSEYFPEDFKefKTIRVNNRKTVPKTEEQANTQLY-YEVVPKDCAEAPFAMIEICDF--WPDAKIPTMGYNRIAATaASVFEsdIDCD-ASC
| .|     |.||  .  |...|.|| .| . . |   ..   ..  || . .    .   .|  ||| ..|.   . .    || .  .. | .  .. 
ekekgkvkchrywPerkn--kklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfv-aevrl--lqtdagPi

AIVSNYGAGRAGSFFVAVLAIEKLQAGEAPNIKEIALSVRSQRPAAIETLSQYMFTYVIALT
   | ||.|.. .   ... ..  .  ..|||  ..| || . . |  ||.| | ..|.   
vvhcsaGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykaile
Phosphatase F40G12.10.AA Subfamily.N_Nematode_1.PD 144-399 25 4.7e-18 56.3 In-house 5-263 (265) Show / Hide 
Range on Protein: 144-399
Range on HMM: 5-263/265
Sequence Identity: 25% (66 aa)

EFKPIDTMkADLEKCQAFKKNID--FSQSENVELYDTNRVKG--GGEADFFYHGSTLTIPSVTtKSTILAQLAIvDspQSLESFWIMVASQKIQRLFILL
||. .  . .| || .|||.. .    . ..|.  | ||||   .. .  . |   ...|... |  | ||  . |  .....||.||  .|.. ...| 
efralkkf-ndeekvkafkeaqeadknrykdvgcldknrvklaeeplpsdyihanyvgtptnp-krficaqaPl-d--ktiadfwymvlqekveaivmlc

GEEELDKPTLSEYFPEDFKEF-------KTIRVNNRKTVPKTEEQAN--TQLYYEVVPKDCAEAPFAMIEICDfWPDAKIPTMGYNRIaataaSVFESDI
   |  |   .||||   .|        ..| |.| ..| |.||...  ..   ||    . ...  | |||  .|..    .      ..|.     . 
kliekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtd-WPdrGvPpadlaal-----elleavr

DCDASCAIVSNYGAGRAGSFFVAVLAIEKLQAGE-APNIKEIALSVRSQRPAAIETLSQYMFTYVIALTY
 ..    | ||.|.  .  . ..|| .|.  ......  ..|.||.| |  ||.| . . | |       
gskgPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvllny
Phosphatase F40G12.10.AA Subfamily.N_Choan_1.PD 161-397 21 8.2e-18 55.7 In-house 23-258 (262) Show / Hide 
Range on Protein: 161-397
Range on HMM: 23-258/262
Sequence Identity: 21% (51 aa)

FKKNIDFSQSENVELYDTNRVKGGG---EADFFYHgSTLTIPSVTTKSTILAQLAIVdsPQSLESFWIMVASQKIQRLFILLGEEELDKPTLSEYFPEDF
..|.   . .|.  ||  |||      . .  |      .|... .   .|  . |  |.||.||| || .||.. . ..  | |.|     |.|.. .|
adenvlknrysnivayDatrvkvtpneenkntDyi-nanfvpgykgekeyiatqgPv--PaslvsfWqmvweqkvsaivmvtreieagklkChryWPden

KEFKTIRVNNRkTVPKTEEQANTQLYYEVVPKDCAEAPFAMIEICdFWPDAKIPTMGYNRIAATAASVFESDIDCDASCAIVSNYGAGRAGSFFVAVLAI
 |   |  . .. ..|..   .  ...  ... .   . ..    |||  .|.   . .   .|    .. ..|.  |    | ||.|..     .....
selklgdvtvk-slseeekktyierkfkleresgetreveqlayt-aWPdhGvPattkellefrkavlkatkkktkaplvihCsaGvGrtGtyialDrlv

EKLQAGEA-PNIKEIALSVRSQRPAAIETLSQYMFTYVIAL
.. .  ...|..  ..| .|   . || || | | . |   
kaveekaealdvkavvaelrkernlmvqtlvqyefvykavl
Phosphatase F40G12.10.AA Subfamily.N_Nematode_6.PD 153-399 20 3.7e-17 53.5 In-house 13-251 (253) Show / Hide 
Range on Protein: 153-399
Range on HMM: 13-251/253
Sequence Identity: 20% (51 aa)

ADLEKCQAFKKNIDFSQSENVELYDTNRVKGGGEADFFYHGSTLTIpSVTTKSTILAQLAIvDspQSLESFWIMVASQKIQRLFILLGEEELDKPTLSEY
|  ....|| |. |  . .|.. .|. |.|  .. ||. | . . | |  ..  | .|  . .  ...| || |. |. .. ..| .  |  |.  .||.
aseseataflkfkdrnrytniqCcdagrlkladdedfyihanlvki-stkprrlictqapl-e--gtieefwkmilssgveyivmlcelvekgkeksaey

FPEDFKEFKTI-RVNNRKTVPKTEEQANTQLYYEVVPKDCAEAPFAMIEICDFWPDAKIPTMGYnrIAATAASVFESdidCDASCAIVSNYGAGRAGSFF
..   . . | .. .   . ...    ..    .. |.  |. .        |||  .|       |||. .   .     .    | ||.| . .   .
lsdkvGdarkitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsfl--salrllsvvkk---dkkPivvhCsaGvGrtGtla

VAVLAIEKLQAGEAPNIKEIALSVRSQRPAAIETLSQYMFTYVIALTY
.| |.  .  ..|..   .| .|  |..|  ||....   | |     
liliilealrlpdfqgvkdllvklreerfravqtevqylyalrcvley
Phosphatase F40G12.10.AA Subfamily.RA.PD 217-399 22 3.9e-16 50.1 In-house 80-264 (266) Show / Hide 
Range on Protein: 217-399
Range on HMM: 80-264/266
Sequence Identity: 22% (42 aa)

PQSLESFWIMVASQKIQRLFILLGEEELDKPTLSEYFPED-FKEFKTIRVNNRKTVpKTEEQANTQLYYEVVPKDCAEAPFAMIEICDF--WPDAKIPTM
...| || |.  || . . .|   .| ..    .|.|..    .  |||. ....  .|. .  ..  . .|. . | .  ...   |  ||..|. |  
eetvedfwrmiweqksativmltelkerkeekcaqywpdeGlvtyGeirvevkdet-vledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpae

GYNRIAATAASVFESDIDCDASCAIVSNYGAGRAGSFFVAVLAIEKLQAGEAPNIKEIALSVRSQRPAAIETLSQYMFTYVIALTY
 .   ..     .  .. . ..    |.||.|.| |    .|...| .  .. |.  ..| |||  ..|| || | | . | |   
gkGmlkllkkvkklqqqsanhpivvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlley
Phosphatase F40G12.10.AA Subfamily.R_Anemone_2.PD 201-396 22 1.1e-15 48.8 In-house 66-257 (262) Show / Hide 
Range on Protein: 201-396
Range on HMM: 66-257/262
Sequence Identity: 22% (44 aa)

VTTKSTILAQLAIVdsPQSLESFWIMVASQKIQRLFILLGEEELDKPTLSEYFPED-FKEFKTIRVNNRKTVPKTEeqaNTQLYYEVVPKDCAEAPFAMI
. | . .|  | .  |. .| || ||  |. . . .|  |||  |  .  |.|..  .......|. ...|  ..    .   ..|  ... |       
yrrkkayiatqaPl--petiedfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsygklvvelkeevelsd---yvlrsfkvkrteeeeerqvrq

EICDFWPDAKIPTMGYNRIAAtAASVFESDIDCDASCAIVS-NYGAGRAGSFFVAVLAIEKLQAGEAPNIKEIALSVRSQRPAAIETLSQYMFTYVIA
 .  |||  .|. | . ..    .| . . ...|.. .|    | ||.| | .    .|...| .  ....   .|.||.. . | .|| | | .   
fhytsWpdegvpesgaslldl-vrqvekaqqesgagpivvhcsaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvl
Phosphatase F40G12.10.AA Subfamily.R_Ecdysozoa.PD 162-395 22 1.4e-15 48.1 In-house 25-263 (269) Show / Hide 
Range on Protein: 162-395
Range on HMM: 25-263/269
Sequence Identity: 22% (53 aa)

KKNIDFSQSENVELYDTNRVKG---GGEADFFYHGSTLTIPSVTTKSTILAQLAIvDSpqSLESFWIMVASQKIQRLFILLGEEELDKPtLSEYFP-EDF
| |    ..|..  .| .|||     |..|  |  .   .    .|. | ||  . ..   .. || |.| |... . .|  ..|..   . |.| || .
kenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPv-ea--tigDfWrmiaeqevtlivmlsnlteknrk-cakyWpiede

KEFKTIRVNNRKTvPKTEEQANTQLYYEVVPKDCAEAPFAMIEI-CDFWP-DAKIPTMGYN--RIAATAASVFE--SDIDCDASCAIVSNYGAGRAGSFF
..  | |.  ..  |... .. .|..  . ..  |.   ..      |. | |.| .     ..   ... .  . . . .   .  . |.||.| |   
vqygdilvklvse-ekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgsrsPivvhCsaGvgrsgifv

VAVLAIEKLQAGEAPNIKEIALSVRSQRPAAIETLSQYMFTYVI
 | ...|.| .  .| |.   .||||.  .. | ||.| |    
aldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyra
Phosphatase F40G12.10.AA PTPc_motif 296-398 20 1.5e-15 58.93 SMART 1-92 (92) Show / Hide 
Range on Protein: 296-398
Range on HMM: 1-92/92
Sequence Identity: 20% (22 aa)

FAMIEICDFWPDA-----KIPTMGYNRIAATAASVFESDIDCDASCAIVSNYGAGRAGSFFVAVLAIEKLQAGEAPNIKEIALSVRSQRPAAIETLSQYM
. .   .  |||      ..|.   . |    ..| .       .. ... .|.||.| | .. .....      ..|...  ..|.||| ...|. ||.
TVHHYHYTNWPDHVEKDSGVPE---DSILEFIRHVRK-------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQYI

FTYVIALT
| | . | 
FCYRCILE
Phosphatase F40G12.10.AA Subfamily.N14.PD 143-399 21 1.9e-15 47.8 In-house 4-273 (275) Show / Hide 
Range on Protein: 143-399
Range on HMM: 4-273/275
Sequence Identity: 21% (60 aa)

PEFKPIDTMKADL-EKCQAFKKNIDFSQSENVELYDTNRVKGGGEAD--F-FYHGSTLTIPSVTTK-STILAQLAIvdsPQSLESFWIMVASQKIQRLFI
.|.  |  ...|   .. . ..| . .. ..|  |. |||.     .    .   |.. ..  ... | | ||  .   ..... || ||  |..| . .
teyeripkkredallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPl---eltvqdfwqmvweqgvqlivm

LLGEEELDKPTLSEYFPEDFKEFKTIRVNNRK----TVPKTEEQANTQLYYEVVPKDCaEAPFAMIEICDfWPDAKIPT-----MGYNRIAATAASVFES
|  |||  |    .|.|.. .. ||.. .. |     . ...  . |.|  . .|    |    ..   | ||| ..|      .. .   .    ..| 
lteeeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpske-ertvwhlqytD-WpdhgvPeDvkgflsfLeevqsvrrktns

DI----DCDASCAIVSNYGAGRAGSFFVAVLAIEKLQAGEAPNIKEIALSVRSQRPAAIETLSQYMFTYVIALTY
.    . .    .    |.||.|   .. | |. |. .|  .||..   .| ||   ..||.|| | | . ..| 
evesvkeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvliky
Phosphatase F40G12.10.AA Subfamily.N5_RR.PD 217-399 21 6.5e-14 42.8 In-house 78-263 (265) Show / Hide 
Range on Protein: 217-399
Range on HMM: 78-263/265
Sequence Identity: 21% (40 aa)

PQSLESFWIMVASQKIQRLFILLGEEELDKPTLSEYFPEDFKE-----FKTIRVNNRKTVPKTEEQANtQL---YYEVVPKDcaeapfAMIEICDFWPDA
|. .. || |.  ...| . .|   .| ..   ..|||.. .      .. . ......| . . . . .|   | | |...       .||| | |   
pntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdaedyeiserygdveikveeiverndysvr-klvlkylervers------vkhywytdWPdh

KIPTMgYNRIAATAASVFESDIDCDASCA---IVSNYGAGRAGSFFVAVLAIEKLQAGEAPNIKEIALSVRSQRPAAIETLSQYMFTYVIALTY
 | .  . . | ||  . .| .|   .    | ||.| |  . .|. .|.. .  .. .|   .| .|   ..| .|| . . .   |      
ksPdd-intlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcly
Phosphatase F40G12.10.AA Subfamily.R_Nematode_3.PD 153-396 16 4.4e-13 40.1 In-house 12-262 (267) Show / Hide 
Range on Protein: 153-396
Range on HMM: 12-262/267
Sequence Identity: 16% (42 aa)

ADLEKCQAFKKNIDFSQSENVELYDTNRVKGGG----EADFFYHGSTLTIPSVTtkSTILAQLAI---VD--SPQSLESFWIMVASQKIQRLFILLGEEE
.  .. . ..|.... . ..|.|. ..||.  |     .| | | . ...|. .  . ||.|       .  . . .| || |..| . .  |    |  
lakknatslskkvsedrrvevpllektrvvLkgygkrfkddfihAnvvecpngl--klIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfve

---LDKPTLSEYFPEDFKEFKTIRVNNRKTVPKTEEQA-NTQLYYEVVPKDCAEAPFAMIEICDFWPDAKIPTMgynriAATAASVFESDIDCDASCAIV
  ..   |||.||. ..  ...  . |.. ...|   ...    ||  . ..     .     |...|       . .| ....    . ..  .    |
edgeeeekcseYypekvdgelkfegvsvkctdikkelsedvekrtlvvtfekkkeftvthllykgWkelnapee-----pkealelikfveksktpvvVH

SNYGAGRAGSFFVAVLAIEKLQAGE-APNIKEIALSVRSQRPAAIETLSQYMFTYVIA
 .|.... .. |.....   . . .. ..  ..|.||. ||.| ....|  ..     
CsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgi
Phosphatase F40G12.10.AA Subfamily.N12.PD 216-394 22 9.3e-13 38.8 In-house 84-263 (270) Show / Hide 
Range on Protein: 216-394
Range on HMM: 84-263/270
Sequence Identity: 22% (42 aa)

SPQSLESFWIMVASQKIQRLFILLGEEELDKPTLSEYFPEDFKE---FKTIRVNNRKTVPKTEEQANTQLYYEVVpkdCAEAPFAMIEiCDFWPDAKIPT
|. |. || |. ..... . ..  | ||.|     |.||  .|   | ...|.. .    ...    .|  |.     ..  .  ..    |||  .|. 
LpktlddfWrmiweknveivvmaCrevelgkkkCeryWpeegeeelefgefevtleeekavdddflirtLkveaq---kesrkvyqfh-ytaWPDhgvPs

MgYNRIAATAASVFESDIDCDASCAIVSNYGAGRAGSFFVAVLAIEKLQAGEAP---NIKEIALSVRSQRPAAIETLSQYMFTYV
  ... .  ..| |   . ||  ..    | ||.|   .  .. | |.|.  |   .. .. |..| ||.|.. |  || . |  
s-aksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvyk
Phosphatase F40G12.10.AA Subfamily.N3.PD 162-392 21 1.1e-12 38.7 In-house 24-252 (261) Show / Hide 
Range on Protein: 162-392
Range on HMM: 24-252/261
Sequence Identity: 21% (51 aa)

KKNIDFSQSENVELYDTNRVKGGGEA-DFFYHG-STLTIPSVTTK-STILAQLAIvdsPQSLESFWIMVASQKIQRLFILLGEEELDKPTLSEYFPEDFK
.|..  .  ..  ||. |||   .  |.       . ||| ..    | .|  .   ... . || ||  ||.. . .|    |  .    .|.||  .|
penlaknryrdilpydatrvklkesetdyinanyvnmeipstglvnryiatqGpl---aktakdfWqmvweqkstlivmlttlverGrvkChqyWPeted

EFKTIrvnNRKTVPKTEEQANTQLYYEVVPKDCAEAPFAMIEICDF--WPDAKIPTMGYNRIaATAASVFESDIDCDASCAIVSNYGAGRAGSFFVAVLA
..     . . . . |.. .. .. |.| || ..    .|    .  ||| ..|.   . .     .| .     .    .    |||.| . .  .|. 
elefg---efsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadfl-efvervrklrsgkeePvvvhCsaGigrtGvlilleta

IEKLQAGEAPNIKEIALSVRSQRPAAIETLSQYMFT
...| |. .. .|   .| || . ..| ||| |   
lalieaaepvypldivrtmrdqramlvqtvsqykfv
Phosphatase F40G12.10.AA Subfamily.R_Sponge_2.PD 217-398 22 1.7e-12 38.3 In-house 77-259 (262) Show / Hide 
Range on Protein: 217-398
Range on HMM: 77-259/262
Sequence Identity: 22% (40 aa)

PQSLESFWIMVASQKIQRLFILLGEEELDKPTLSEYFPEDFKEFKTIRVNnRKTVPKTEEQANTQLYYEVVPKDCAEAPFAMIEICDF--WPDAKIPTMG
....| || ||  .|.. . .|   || .|    .|.||  .| ...    . |. ..|. |.  .    . |. ...  | ..|  ||. . |.     
ketveDfWRmvweykvstivmltnleengkekcakYWPekvdeeveygkf-kvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkda

YNRIAATAASVFESDIDCDASCAIVSNYGAGRAGSFFVAVLAIEKLQAGEAPNIKEIALSVRSQRPAAIETLSQYMFTYVIALT
..  .  . .   . . .  .| . |.||.|.| .    .|.|.| |  .. |.  ..|..|.  ....|| | . ..|     
tsllelikrvlraqkksgnkaitvvCsdgvgrtGtfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalle
Phosphatase F40G12.10.AA Subfamily.RG.PD 216-395 18 4e-12 37.0 In-house 79-258 (264) Show / Hide 
Range on Protein: 216-395
Range on HMM: 79-258/264
Sequence Identity: 18% (33 aa)

SPQSLESFWIMVASQKIQRLFILLGEEELDKPTLSEYFPE--DFKEFKTIRVNNRKTVPKtEEQANTQLYYEVVPKDCAEAPFAMIEICDFWPDAKIPTM
... .| || |.  .. | . .|   .|  .     |.|.  .  |.....|.  ..  . ..   ...  .   .|  .        .  |||. |.  
lketiedFWrmiWehnaqiivmltdldekgrrdedvyWPkkdeplelealkvtllskekl-skytvrdfvlkntkddkekervvrqyhytkWPdmgsPes

GYNRIAATAASvFESDIDCDASCAIVSNYGAGRAGSFFVAVLAIEKLQAGEAPNIKEIALSVRSQRPAAIETLSQYMFTYVI
.. .     .   .  .      .. ..|.|||| . .    ...|.. || |. ...  .|..||  ..|  ||.| | . 
tlfvlifvkke-eaankeeaGPivvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiyda
Phosphatase F40G12.10.AA Subfamily.N_Nematode_4.PD 159-397 21 4.6e-11 33.5 In-house 21-260 (264) Show / Hide 
Range on Protein: 159-397
Range on HMM: 21-260/264
Sequence Identity: 21% (51 aa)

QAFKKNIDFSQSENVELYDTNRVKGGGE--ADFFYHGSTLTIPsvTTKSTILAQLAIvdsPQSLESFWIMVASQKIQRLFILLGEEELDKPTLSEYFPED
.|..|| | .. ...   | .||          . | | ...|       | .|  .   ...|. || ||  .||. . .|.| .    . |.||. ..
saseknsdknryadilcidetrvvlknrdpdndyihaswmrmP--dkfryistqGPl---ketlsdfwhmvytekiavvvmlcdlieegvekcaryypek

FKEFKTIRVNNRKTVPKTEE-QANTQL---YYEVVP--KDCAEAPFAMIEI-CDFWPDAKIPTMGYNRIAATAAsVFEsdIDCDASCAIVSNYGAGRAGS
 ...   . . | |.||  |.. |      ..   ||..  |. .  .  | |.|   ||    | | .   . .    .    | ||. ..    .|  
sekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklyka-vkk--kkkekPivvhcsaGvGrtat

FFVAVLAIEKLQAGEAPNIKEIALSVRSQRPAAIETLSQYMFTYVIAL
...     .. .|   .|. |  |. .  |..| .|. .         
lvGidyatirirenseievldivrelramrlkavqshlqflfllvvli
Phosphatase F40G12.10.AA Subfamily.RB.PD 169-395 19 7.8e-11 32.8 In-house 31-255 (261) Show / Hide 
Range on Protein: 169-395
Range on HMM: 31-255/261
Sequence Identity: 19% (43 aa)

QSENVELYDTNRVKG---GGEADFFYHGsTLTIPSVTTKSTILAQLAIVdsPQSLESFWIMVASQKIQRLFILLGEEELDKPTLSEYFPEDFKEFKTIRV
. .|.  ||..|||      |.|  |   .  ||  ...   .|    .  |.. . || ||  .| . . .|    |  |    ||.|.| ....   .
rftnilpydhsrvkLaalkdesdtdyin-anyipgynspreyiatqGPl--petvddfWrmvwekkssiivmltqlvEkgkekceeYWPadeepvlyGdi

NNRKTVPKTEEQAnTQLYYEvVPKDCAEAPFAMIEICdFWPDAKIPTMGYNRIAATAASVFESDIDCDASCAIV-SNYGAGRAGSFFVAVLAIEKLQAGE
  |....  .   .. . |.  .      .    |||  .|      .. . .   . . .. ..  .|    | ||.| |...... .  ..  .  ..
kvtllaekeldew-virefk-iekgkekrkvrqyhft-sWpdhgvPektktlldfvrtvreaiekkaskkPivvHCsaGvGRtGtfialdrllqaieend

APNIKEIALSVRSQRPAAIETLSQYMFTYVI
|..|   . |..||.| . .           
yvdvfgvvaelReeRnllvqtekqyifihec
Phosphatase F40G12.10.AA Subfamily.N_Choan_2.PD 216-398 20 1e-10 32.2 In-house 74-263 (266) Show / Hide 
Range on Protein: 216-398
Range on HMM: 74-263/266
Sequence Identity: 20% (38 aa)

SPQSLESFWIMVASQKIQRLFILLGEEELDKPTLSEYFPEDFKEFKTIRVNNRKTVPKTEEQANTQLYYEVVPKDCAEAPFAMIEICDFWPDAKIPTMGY
| .|.||| |. ..| . . .. | || ..   . |.|.. ||  ...  . |..  .||...  .  ..  .   |    .|||  .|..       . 
lpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkladgkikvlalseekeegyiltrlrlekkgetrrlvHfwyntWpdhgvpreed

-----NRIAATAASVFESDIDCDAS-CAIV-SNYGAGRAGSFFVAVLAIEKLQAGEAPNIKEIALSVRSQRPAAIETLSQYMFTYVIALT
. .. . | ..  . | .   .|    | ||.| . .   |.. |.  .  .. .|   .| .|.|...  || . |   ..        
sslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtliaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavve
Phosphatase F40G12.10.AA Subfamily.RK.PD 217-399 17 7.4e-10 29.3 In-house 81-265 (267) Show / Hide 
Range on Protein: 217-399
Range on HMM: 81-265/267
Sequence Identity: 17% (33 aa)

PQSLESFWIMVASQKIQRLFILLGE-EELDKPTLSEYFPEDFKE-FKTIRVNNRKTVPKTEEQANTqlyYEVVPKDCAEAPFAMIEICDF--WPDA-KIP
.. .. || .|  ..   . .|     |  .   ..|.||| .  .. |.|.  .. ....  . .   . |     .   . ...  .|  ||.  ..|
qetvkdfWrlvydencasivmlteldvevgrvkClkyWPedtevrygdikvelveaeldadlvvri---frveklargqeeirevrqfqflgWpeyrdvP

TMGYNRIaATAASVFESDID-CDASCAIVSNYGAGRAGSFFVAVLAIEKLQAGEAPNIKEIALSVRSQRPAAIETLSQYMFTYVIALTY
.     . .  . | .|. .  .    .    ||||.| | .    .| ..  .  .. ... ..|....  .||  ||.| | ..|. 
vskrsll-klirrvkksqeeeeeGrivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvilea
Phosphatase F40G12.10.AA Subfamily.N1.PD 160-396 21 7.6e-10 29.6 In-house 24-263 (268) Show / Hide 
Range on Protein: 160-396
Range on HMM: 24-263/268
Sequence Identity: 21% (52 aa)

AFKKNIDFSQSENVELYDTNRVKGGGEADFFYHGSTLTIPSVtTKSTILAQLAIvdsPQSLESFWIMVASQKIQRLFILLGEEELDKPTLSEYFPEDFKE
...| .. .  .|. ||  |.|   .   .   | . .. .  .. ||.|  .   |.  . || ||  |. . . .|    | ..    .|.|.. .| 
klpenrglnryrdvspydhsrikleradvdyinaslveleea-krrYiLtqGPL---phtadHFWqmvWeqnskavimLnkvvEknqikCaqywpqeeee

FkTIRVNN----RKTVPKTEEQANTQLYYEVVPKDCAEAPFAMIEICDFWPDAKIPTMGYNrIAATAASVFESDI-DCDASCA-IVSNYGAGRAGSFFVA
 .. ...     | . . ... ...  .|.  ..  |.   .      |||  .|.     .      | || .   | ..| |. .| ||.|.. .   
a-ellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaa-fLkfLfkvresgsLssdvgpavihCsagigrsgtlslv

---VLAIEKLQAGEAPNIKEIALSVRSQRPAAIETLSQYMFTYVIA
 .. ||| .  .| .||.  | .|..|   | |  |  |.|.    
dtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiai
Phosphatase F40G12.10.AA Subfamily.N9.PD 217-399 19 7.9e-10 29.6 In-house 79-273 (275) Show / Hide 
Range on Protein: 217-399
Range on HMM: 79-273/275
Sequence Identity: 19% (38 aa)

PQSLESFWIMVASQKIQRLFILLGEEELDKPTLSEYFP---EDFKEFKTIRVNNRKTVPKTEEQaNTQLYYE-VVPKDCAE-APFAMIEicdfWPDAKIP
... . || ||  |..  . .    .|  .   ..|.|   |. .|| ...|.| ... . . .  ..|  . |  ..  .   | ..     |||  .|
kktvsdfwrmvweqevlvivmttrvvergrlkcgqywpleeessaefgdlsvsnveveveedyk-vrvleiknvkteesrkvthfqfls----wPdyGvP

TMGYNRI-----AATAASVFESDI------DCDASC-AIVSNYGAGRAGSFFVAVLAIEKLQAGEAPNIKEIALSVRSQRPAAIETLSQYMFTYVIALTY
  . . .     .  . ... ...      ...     .    | ||.|.|    .....|.  .  ...|    .|.||  .| |||.| |.  | |  
ssaaslldvlekvrekqalavkelgdeskghlsgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavley
Phosphatase F40G12.10.AA Subfamily.N6.PD 146-399 19 5.6e-09 26.6 In-house 50-293 (295) Show / Hide 
Range on Protein: 146-399
Range on HMM: 50-293/295
Sequence Identity: 19% (50 aa)

KPIDTMKADLEKCQAFKKNIDFSQSENVELYDTNRVkgggeadffyHGSTLTipSV-TTKSTILAQLAIvdsPQSLESFWIMVASQKIQRLFILLGEEEL
| |  .  |.  .   .  |.  .. ..| ....           .|..    |  ..|. | .| ..   .. .. || ||  .. . . ..| |  | 
lPfDhtrvilkdgepsvpgsdYiNanyirlpkasks----------sgenve--seehqkryiatqgcL---kdtvsdFWrmvwqensrvivmttkever

DKPTLSEYFPEDFKEFKTIRVnNRKTVPKTEEQANTQLYYEVVPKDCAEAPFAMIEI-CDFWPDAKIPTMGYNRIaATAASV--FESDIDCDASCAIVSN
  . |.|.  .. .| .. . ...  ..... |   ..|  ||  .    ...     |||. .|.  .  .      |   ....    .. .  . | 
gknkCarYWPdeetkketGvi-tvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvl-nfledvnkkqeelekagpivvhcs

YGAGRAGSFFVA--VLAIEKLQ-AGEAPNIKEIALSVRSQRPAAIETLSQYMFTYVIALTY
||.|.| |   || | . . .    .|...  .|||||   . |  || | |... .|   
aGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqfy
Phosphatase F40G12.10.AA Subfamily.R_Nematode_2.PD 219-397 22 2.9e-08 24.2 In-house 81-257 (261) Show / Hide 
Range on Protein: 219-397
Range on HMM: 81-257/261
Sequence Identity: 22% (39 aa)

SLESFWIMVASQKIQRLFILLGEEELDKPTLSEYFPEDFKEFKTIRVNNRKTVpKTEEQANTQLYYEVVPKDCAEAPFAMIEI----CDFWPDAKIPTMG
|.||.||. .|.... .|    |  |   .|||| . ..  ..   . ||| ..|. .. ...  ..  . ..  ||   .|||  .|        |   
tsedfWamviqekvekivmlcqkvekekekceeYfpletsqkldlgrfsiktv-saekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPksh

ynriaATAASVFESDIDCDASCAIVSNYGAGRAGSFFVAVLAIEKLQAGEAPNIKEIALSVRSQRPAAIETLSQYMFTYVIAL
 ..|   . .    .    | ||...|  .    ....| .  ...|    .|..|. .| | ||...  . ||         
-----aelfeLlelvkksekPivvhCsaGiGRtmafigteylareveadptieltealkelrehRwkgiqtesqlywltlgal
Phosphatase F40G12.10.AA Subfamily.RC.PD 219-395 18 6.7e-07 19.7 In-house 100-282 (288) Show / Hide 
Range on Protein: 219-395
Range on HMM: 100-282/288
Sequence Identity: 18% (34 aa)

SLESFWIMVASQKIQRLFILLGEEELDKPTLSEYFPEDFKEFKTIRVNNRKTvPKTEEQanTQLYYEVVPKDCAEA-PFAMIEIcDFWPDAKIPTMGYNR
... || |.  .|.. . .|   .| |.   .||. |  . .  . |. ..|  |. .   .   .|.| |   ..     |.    |.. ..|. .   
tvddfwrmiferkvkvivmltelkeGdrekcaeyweeGkrayGdvevdlkdt-dkssdy--ilrklelvnkkrkdsrevtqiqy-tswsveqlpeepkel

IAA--------TAASVFESDIDC-DASCAIVSNYGAGRAGSFFVAVLAIEKLQAGEAPNIKEIALSVRSQRPAAIETLSQYMFTYVI
             |.  .   .   .  . |..|.| |      .| |.| |  .. ..   .| .||  ...  ||.. | .    
lkliqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydv
Sequence
Name Sequence Type Origin Length Description Download
F40G12.10.AA Protein None 438 None Fasta, JSON
F40G12.10.NA RNA None 1314 None Fasta, JSON
F40G12.10.AA.PD_140-401 Protein Phosphatase Domain None 262 None Fasta, JSON