Gene F57H12.5
F57H12.5
Species: C.elegans
Alias: F57H12.5
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of F57H12.5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | F57H12.5.AA | Subfamily.N23.PD | 195-501 | 19 | 2.4e-15 | 47.3 | In-house | 52-348 (350) | Show / Hide |
Range on Protein: 195-501 Range on HMM: 52-348/350 Sequence Identity: 19% (58 aa) SKQKTKMWLGMPSALNFCNKNNDIQKIREEF-GFLDSLVCNKTTEAFEANKVRNREGCP-KIYDENRVQLN---RPGHEDvNYINAsvitltdvcrrmac ..... . || . |||..... .. . . .. . ...| | .. |.|||.|. .|| .| .||||.|. . gqeaiaadqsiasakrmsnknrqfnpdllpyhlqpttitavpqprhlqtegsGqqqgtpdsrhdpnrvklqqstqpgqqd-dyina-------------- vpAYVhlvvlyFVIFQFEHKLIVAQLPQmenESFVEDFWYMIYQEQIHLVYLMVPD-DKLKNTTTSLFNDENGGYQYTGKMFINNRRADVSGDPKEYTIE ..|..| |. .| . ||| |....| .. ... . .. | . . ..| . |.. . .. | |..... . | .|.. | --tyl------keltpmsPpfiatqgPi---astlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslkslrssegwiervlh VLPEGNSD-SVICQVhHHAPWKHLQQ---PPKTLPIIKMIHQFLSE-KQVQNA-----GVCVVSLFGCGRACSFIGALYAINQL--NNGIEpNICEIMKN | .. | . | ... ... ... .... . . . | ||. |||..| .||| || .......||| |. ... .| .| lqhndvstvrlvchl-htttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagngii-niprvvrr IKQQRPGGVESFAQYASIYAIVFDY . . lrqqRkymvqkkvilkklyeavlea |
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| Phosphatase | F57H12.5.AA | Subfamily.N_Nematode_5.PD | 221-502 | 52 | 6.2e-111 | 360.5 | In-house | 2-257 (258) | Show / Hide |
Range on Protein: 221-502 Range on HMM: 2-257/258 Sequence Identity: 52% (138 aa) IREEFGFLDSLVCNK-TTEAFEANKVRNREGCPKIYDENRVqlnRPGHEDVNYINASVITLTDvcrrmacvpayvhlvvlyfvifqFEHKLIVAQLPQME ...|| |.||..|| |..|||.|. .||. ..||.||.|| ....||..|||||.|.|.|.|.|||..|||....| ||||.|.|||.|..|.|. lktefeklaslkpnketckafeknlkknrskdvkilDetrV---kltdeddsYinaskikldd-----------------------lekkliltQlPlpd NEsfvEDFWYMIYQEQIHLVYLMVPDDKLKNTTTSLFNDENGGYQYTGKMFINNRRADVSGDP-KEYTIEVLPEGNSDSVICQVHHHAPWKHLQQPPKTL |.|..||.|..|.|..|.| |...||||||||...|. |. ||||.||||||.|.||...|.|...||. ..|.|. ..|| .|...||.||..||.|.| te---edFWrmvyqekitsvvllvedeelketavsffpletgdylnlgkmfinnrkvevkedekkeytvevlpegcsesvfakvyhlttWkkkkvPdkvk PIIK-MIHQFLSEKQVQNAGVCVVSLFGCGRACSFIGALYAINQLNNGIEPNICEIMKNIKQQRPGGVESFAQYASIYAIVFDYI || .|.|||..|.....||.|||||.||||.||.|.|..||||.|||..||||.||.|.||| kvikraiekvlskkqgknapvvvvsdlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaavldyi |
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| Phosphatase | F57H12.5.AA | PTPc | 220-503 | 19 | 2.3e-57 | 197.79 | SMART | 1-308 (308) | Show / Hide |
Range on Protein: 220-503
Range on HMM: 1-308/308
Sequence Identity: 19% (67 aa)
KIREEFGFLDSL-----------VCNKTTEAFEANK--VRNREGC-PKIYDENRVQLNRPGH-----EDVNYINASVITLTDVCRRMACVPAYVHLVVLY
...||| |... .|..|. ....|. .|| | . ||..|| |..| . |. .||||. |
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY-------------------
FVIFQFEHKLIVAQLPQMENESFVEDFWYMIYQEQIHLVYLMVPDDKL---------KNTTTSLFNDENGGYQYTGKMFINNRRADVSG-DPKEYTIEVL
.... |..| |. .. .|||| |..|...| . .. .. .. . || .. |........ .. | . .|.||
----WRPKRYICTQGPL---PHTIEDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE---PMTYGHITVTCKSEEKCPDDYTMRTFEVT
PEGN--------SDSVICQVHHHAPWKHLQQPPKTLPIIKMIHQFLSEKQVQ-------------------NAGVCVVSLFGCGRACSFIGALYAINQLN
. |. |.. .. ..|. |.... |. . .....|.|. . .. . .. ..|.. ||||...|... ....|..
NTGCNCKYSMACSETRTVTHYHYTNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIE
NGIEPNICEIMKNIKQQRPGGVESFAQYASIYAIVFDYIA
| ..|..|.| . .|||| |....|| ..| .. .||
N---VDIFQIVKMMRNQRPGMVQTEEQYIFCYRCILEYIK
|
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| Phosphatase | F57H12.5.AA | Y_phosphatase | 243-500 | 20 | 1.6e-50 | 178.85 | Pfam | 1-243 (243) | Show / Hide |
Range on Protein: 243-500 Range on HMM: 1-243/243 Sequence Identity: 20% (57 aa) NKVRNREGCPKIYDENRVQLNRP-GHEDVNYINASVITLTDVCRRMACVPAYVHLVVLYFVIFQFEHKLIVAQLPQMENESFVEDFWYMIYQEQIHLVYL || .|| .|| .|| | .. |.|| .||||. |. .. ... |..| |. . .|||| |..|... . NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDG----------------------PYWNPKAYICTQGPMP---HTIEDFWRMVWQQKC-TCIV MVPDDKLKNT-TT---SLFND-ENGGYQYTGKMFINNRRADVSGDPKEYTIEVLPEGNSD-----SVICQVHHHAPWKHLQQPPK-TLPIIKMIHQFLSE |. .. .. . | . |... |........ .. ..||..... | . . .....|. |.. . |. . .....|.|. . MLCNCMEMGRDEKTCHQYWPDNKEGQPMTYGDFQVTCVSEEH---CPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKW KQVQNAG---VCVVSLFGCGRACSFIGALYAINQLNNGIEPNICEIMKNIKQQRPGGVESFAQYASIYAIVFD .. ...| ..|.. ||||.. |... ... |. .. ...|..| | . .|||| |....|| .| .. . QPNPDHGCPPIVVHCSAGCGRTGTFCAIDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE |
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| Phosphatase | F57H12.5.AA | PTPc_motif | 399-500 | 20 | 9.7e-22 | 79.47 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 399-500 Range on HMM: 1-92/92 Sequence Identity: 20% (22 aa) ICQVHHHAPWKHL-----QQPPKTLPIIKMIHQFLSEKQVQNAGVCVVSLFGCGRACSFIGALYAINQLNNGIEPNICEIMKNIKQQRPGGVESFAQYAS .. ..|. |.. | .|...|... . ..|.. ||||.. |... ....| ..|....| ...|||| |....|| TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQYIF IYAIVFD .|... . CYRCILE |
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| Phosphatase | F57H12.5.AA | Subfamily.R_Anemone_1.PD | 239-502 | 22 | 2.3e-21 | 67.5 | In-house | 21-257 (258) | Show / Hide |
Range on Protein: 239-502 Range on HMM: 21-257/258 Sequence Identity: 22% (58 aa) AFEANKVRNREGCPKIYDENRVQLNR-PGHEDVNYINASVITLTDvcrrmacvpayvhlvvlyfvifqFEHKLIVAQLPQmenESFVEDFWYMIYQEQIH ..|| .|| .|. || |.. ..|. .||||| . .| .. |..| | |.||||| |. ||.| | rkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasd-----------------------ktrafiatqapl---eetvedFWrmvwqekig L-VYLMVPDDKLKNTTTSLFNDenGGYQYtGKMFINNRRADVSGDPKEYTIEVLPEGNSDSVICQVHHHAPWKHLQQPPKTLPIIKMIHQFLSEKQVQNA | .. |.... . | . .| |.. .. |. .| .| |. . ...... . . |.| . | .. .... .. .... ... | | viVmLtnliegekkkchqYwPd--steky-gelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqksslagar GVCVVSLFGCGRACSFIGALYAINQLNNGIEPNICEIMKNIKQQRPGGVESFAQYASIYAIVFDYI | ||. |. ..|. . .| ...|.|...|| |.. ||. |. .|.... pvvvhCsaGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavleal |
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| Phosphatase | F57H12.5.AA | Subfamily.N_Nematode_4.PD | 308-502 | 18 | 4.2e-18 | 56.5 | In-house | 66-263 (264) | Show / Hide |
Range on Protein: 308-502
Range on HMM: 66-263/264
Sequence Identity: 18% (36 aa)
HKLIVAQLPQMEnesFVEDFWYMIYQEQIHLVYLMVP--DDKLkNTTTSLFNDENGGYQYTGKMFINN--RRADVSGDPK--EYTIEVLP---EGNSDSV
. | .| | | ..|||.|.|.|.|. | .. .. . . . . .... . || |. .. | |.. . . .|. .. . .
fryistqGPlke---tlsdfwhmvytekiavvvmlcdlieegv-ekcaryypeksekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapsepl
ICQVHHHAPWKHLQQPPKTLPIIKMIHQFLSekQVQNAGVCVVSLFGCGRACSFIGALYAINQLNNGIEPNICEIMKNIKQQRPGGVESFAQYASIYAIV
|. | .. |.||.. . .. ..| | ||.....| || ....| .. .|...... | . | | |. .. .. ...
vvkhvqvdwwrdqvaPldaapviklykavkk--kkkekPivvhcsaGvGrtatlvGidyatirirenseievldivrelramrlkavqshlqflfllvvl
FDYI
ielf
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| Phosphatase | F57H12.5.AA | Subfamily.N6.PD | 229-502 | 21 | 1.6e-17 | 54.6 | In-house | 28-294 (295) | Show / Hide |
Range on Protein: 229-502 Range on HMM: 28-294/295 Sequence Identity: 21% (60 aa) DSLVCNKTTEAFEANKVRNREGCPkiYDENRVQLN--RPGHEDVNYINASVITLTDVCRRMACVPAyvhlvvlyfvIFQFEHKLIVAQLPQmenESFVED . . ... . . ...| | .. .| .|..|| |. | . .||||. |.| . . . ... . .. |..| ... |.||| | klysrkegekienkeknryknilP--fDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenve----------seehqkryiatqgcL---kdtvsd FWYMIYQEQIHLVYLMVPD-DKLKNTTTSLFNDENGGYQyTGKMFINNRRADVSGDP--KEYTIEVLPEGNSDSVICQVHHhAPWKHLQQPPKTLPIIKM ..||. ... .. . .. || . . ||. . ||.. ... . . | .|.... . .. | | |. || .. ....... ... FWrmvwqensrvivmttkevergknkCarYWPdeetkke-tGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhf-kaWPdhgvpkdpgvvlnf IHQFLSEK-QVQNAG-VCVVSLFGCGRACSFIGA---LYAINQLNNGIEPNICEIMKNIKQQRPGGVESFAQYASIYAIVFDYI ....|| ..| |.||. .|| | |.| .. .| ...|....|| | | . ||| .| .||| ledvnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqfyi |
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| Phosphatase | F57H12.5.AA | Subfamily.R_Ecdysozoa.PD | 306-502 | 22 | 2.1e-17 | 54.0 | In-house | 68-268 (269) | Show / Hide |
Range on Protein: 306-502 Range on HMM: 68-268/269 Sequence Identity: 22% (46 aa) FEHKLIVAQLPQmenESFVEDFWYMIYQEQIHLVyLMVPDDKLKNTTT-SLFNDEnGGYQYTgKMFINNRRADVSGDPKEYTIEVLPEG----NSDSVIC ..| |.|| | |. ..||| || . ...|. |. . . || . .| || .. .. . . .| . ...|. . . | .. ekkkfiaaqdPv---eatigDfWrmiaeqevtli-vmlsnlteknrkcakyWpie-devqyg-dilvklvseekhsdyiireldvskkkeesvedsrkvv QvHHHAPWK-HLQQPPKTLPIIKMIHQFLSEKQVQ-----NAGVCVVSLFGCGRACSFIGALYAINQLNNGIEPNICEIMKNIKQQRPGGVESFAQYASI . || . | . ..|.|.| . .. . .. . | | ||. |. ..||... .|.|..|....||. |.|..|| .| . | q-ysytgWksDskvPevargllklieqvrelyklnklsgsrsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvfl YAIVFDYI |. yraladys |
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| Phosphatase | F57H12.5.AA | Subfamily.N12.PD | 309-502 | 19 | 4e-17 | 53.0 | In-house | 76-269 (270) | Show / Hide |
Range on Protein: 309-502 Range on HMM: 76-269/270 Sequence Identity: 19% (39 aa) KLIVAQLPQMeneSFVEDFWYMIYQEQIHLVYLMVPDDKLKNTTTSLFNDENGGYQY-TGKMFINNRRADVSGDPkeYTIEVLPE--GNSDSVICQVHHH . | || | . ..||| ||.. ....| .. |. . . |.|. . .|.. ... . . | ..| | . .. | |.. eyiaaqgPLp---ktlddfWrmiweknveivvmaCrevelgkkkCeryWpeegeeelefgefevtleeekavddd--flirtLkveaqkesrkvyqfhyt ApWKHLQQPPKTLPIIKMIHQFLSEKQVQNAGVCVVSLFGCGRACSFIGALYAINQLNNGIEP---NICEIMKNIKQQRPGGVESFAQYASIYAIVFDYI | | . | .. .....|... . .. ..| ..| |.||. | |. ..|.... | .. ... ....||. | .|| .| | ... a-WPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv |
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| Phosphatase | F57H12.5.AA | Subfamily.RG.PD | 304-500 | 18 | 1.3e-16 | 51.6 | In-house | 66-261 (264) | Show / Hide |
Range on Protein: 304-500 Range on HMM: 66-261/264 Sequence Identity: 18% (37 aa) FQFEHKLIVAQLPQMEnesFVEDFWYMIYQEQIHLVYLMVP-DDKLKNTTTSLFNDENGGYQYtGKMFIN--NRRADVSGDPKEYTIEVLPEGNSDSVIC .. ... ||.| | | .|||| ||.... ... .. |.|... .. . .... .. ... .. .. . ...... .... yrrskeyivtqgplke---tiedFWrmiWehnaqiivmltdldekgrrdedvyWPkkdeplel-ealkvtllskeklskytvrdfvlkntkddkekervv QVHHHAPWKHLQQPPKTLPIIKMIHQFLSEKQVQNAGVCVVSLFGCGRACSFIGALYAINQLNNGIEPNICEIMKNIKQQRPGGVESFAQYASIYAIVFD . .| . | ..| .||. . .... .. .. . |. | |||. .| ..||.. |. ...| |...||| |..|| || .. . rqyhytkWPdmgsPestlfvlifvkkeeaankeeaGPivvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydalle |
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| Phosphatase | F57H12.5.AA | Subfamily.N5_RR.PD | 322-502 | 21 | 1.9e-16 | 51.1 | In-house | 79-264 (265) | Show / Hide |
Range on Protein: 322-502 Range on HMM: 79-264/265 Sequence Identity: 21% (38 aa) SFVEDFWYMIYQEQIHLVYLMVPDDKLKNTTTSLFNDENGGYQYTGKMFINNRRADVSGDPKEYTIEVLPEGNSDSVICQVHH--HAPWKHLQQPPKTLP . ..||| |||||..... .. ... . . .. .|. ... . . . . ..|... | .. .| .|.| .. |..| .. .... ntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdaedyeiserygdveikveeiverndysvrklvlkylerversvkhywytdWPdhksPddint IIKMIHQFLS---EKQVQNAGVCVVSLFGCGRACSFIGALYAINQLNNGIEPNICEIMKNIKQQRPGGVESFAQYASIYAIVFDYI .... . |.. . | | | | ||. ||... |..||.. | .. .|. |....| | |.. || |. ..| lldlvleveesreeenaklaPvvvhcsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclyl |
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| Phosphatase | F57H12.5.AA | Subfamily.RA.PD | 305-502 | 21 | 2.3e-16 | 50.8 | In-house | 67-265 (266) | Show / Hide |
Range on Protein: 305-502 Range on HMM: 67-265/266 Sequence Identity: 21% (42 aa) QFEHKLIVAQLPQMENesfVEDFWYMIYQEQIHLVYLMVPDDKLKNTTTSLFNDENGGYQYTG-KMFINNRRADVSGDPKEYTIEVLPEGN---SDSVIC . .| | || |. | ||||| ||.. . . . .. .. |.. . ..| . | .. ... .. ... .. ||.. .. |.| . rekdkfiaaqGpkeet---vedfwrmiweqksativmltelkerkeekcaqywpdeGlvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvr QVHHHApWKHLQQPPKTLPIIKMIHQFLSEKQVQNA-GVCVVSLFGCGRACSFIGALYAINQLNNGIEPNICEIMKNIKQQRPGGVESFAQYASIYAIVF . | .. | .. ..|.... . .|.. . . | | ||. .|| ..... .. |..|....||| |..|| || .. .|| qfhfts-wpevGvpaegkGmlkllkkvkklqqqsanhpivvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvll DYI eyi |
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| Phosphatase | F57H12.5.AA | Subfamily.RK.PD | 221-502 | 19 | 9.1e-16 | 48.6 | In-house | 2-266 (267) | Show / Hide |
Range on Protein: 221-502 Range on HMM: 2-266/267 Sequence Identity: 19% (57 aa) IREEFGFLDSLVCNKTTEAF-----EANKVRNREGCPKIYDENRVQLNRPGHEDVNYINASVItltdvcrrmacvpayvhlvvlyfVIFQFEHKLIVAQL ..||| |.|. . .| . . |. .|| . || .|.| .. .||||..| .. ..||.| | lkeefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgdssdyinaali-----------------------dsykrpaafivtqg PQMEnesFVEDFWYMIYQEQIHLVyLMVPDDKLKN--TTTSLFNDENGGYQYtGKMFINNRRADVSGD--PKEYTIEVLPEGNSDSVICQVHHHAPWKHL | |.||| ..|.|. . .|. . . .. . . |.. .| |.. .. .|.. | . ...| | |... .. .. | . . Plqe---tvkdfWrlvydencasi-vmlteldvevgrvkClkyWPedtevry-gdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpey -QQPPKTLPIIKMIHQFLSEKQVQNAGVCVV-SLFGCGRACSFIGALYAINQLNNGIEPNICEIMKNIKQQRPGGVESFAQYASIYAIVFDYI | . ..|.|.. . .. ...| || | |.||. || .. ... .. ...|....... || ||.| ...... rdvPvskrsllklirrvkksqeeeeeGrivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvileal |
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| Phosphatase | F57H12.5.AA | Subfamily.R_Sponge_2.PD | 309-502 | 22 | 2e-15 | 47.8 | In-house | 68-261 (262) | Show / Hide |
Range on Protein: 309-502 Range on HMM: 68-261/262 Sequence Identity: 22% (43 aa) KLIVAQLPqMenESFVEDFWYMIYQEQIH-LVYLMVPDDKLKNTTTSLFNDENGGYQYTGKMFINNRRADVSGDPKEYTIEVLPEGNSDS-VICQVHHHA |..| | . .. ||||| |.. ... .| | .. |. .. . ..... . ||. .. . . | . .... |.|.. . . .|. | ayiatqgP-l--ketveDfWRmvweykvstivmltnleengkekcakYWPekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfv PWKHLQQPPKTLPIIKMIHQFLSEKQV-QNAGVCVVSLFGCGRACSFIGALYAINQLNNGIEPNICEIMKNIKQQRPGGVESFAQYASIYAIVFDYI ..| .. .....|.. | ... .| . || | ||. .|| ...|.. | .. |..|... .|.| |. ||| |. .. .|| aWpehevPkdatsllelikrvlraqkksgnkaitvvCsdgvgrtGtfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalleyi |
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| Phosphatase | F57H12.5.AA | Subfamily.RC.PD | 241-501 | 21 | 7.5e-14 | 42.5 | In-house | 24-286 (288) | Show / Hide |
Range on Protein: 241-501
Range on HMM: 24-286/288
Sequence Identity: 21% (57 aa)
EANKVRNREGCPKIYDENRVQLNRPGHEDVNYINASVITLTDVCrRMACVPAYVHlvVLYFVIFQFEHKLIVAQLPQMENesfVEDFWYMIYQEQIHLVY
| || .|| || |||.|.. . . . | . | |. . .. .|.| || |. | |.||| ||........
eenksknrysdvlpydynrvelkhelemskesehdsdessdddi-dseegskyin--asfidsykkpekyiaaqGplket---vddfwrmiferkvkviv
lMVPDDKLK--NTTTSLFndeNGGYQYTGKMFINNRRADVSGDPKEYTIEVLPEGNSDSVICQVHHHAPWKHLQQPPKTLPIIKM---IHQFLSEKQVQN
|. . | . . . . | . | . .. . | | | .|. . . || .. | | | . ..|...| | .|. .|
-mltelkeGdrekcaeyw---eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkrsse
AGVCVV-------SLFGCGRACSFIGALYAINQLNNGIEPNICEIMKNIKQQRPGGVESFAQYASIYAIVFDY
| .|. ||. | .. |. .. ...|.....||. |. ..|| .| .. ..
afknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlvet
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| Phosphatase | F57H12.5.AA | Subfamily.N_Choan_1.PD | 225-502 | 16 | 2.7e-13 | 40.8 | In-house | 6-261 (262) | Show / Hide |
Range on Protein: 225-502 Range on HMM: 6-261/262 Sequence Identity: 16% (47 aa) FGFLDSLVCNKTTEAF--EANKVRNREGCPKIYDENRVQLNRPGHEDvnyinasvitltdvcrrmacVPAYVHlvVLYFVIFQFEHKLIVAQLPQMEneS . | .. ..|..| ..|...|| || ||.... .. |. . .. |..|..| | . | yeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenk--------------------ntDyin--anfvpgykgekeyiatqgPvPa--s fVEDFWYMIYQEQIHLVYLM---VPDDKLKntTTSLFNDENGGYQYtGKMFINNRRADVSGDPKEYTIEVLPEGNSDSVICQVHHHApWKHLQQPPKTLP ...|| |......... .. . .||| . ||| .. |.. ... .. . | .... |.. . |... | | | .| . -lvsfWqmvweqkvsaivmvtreieagklk--ChryWPdenselkl-gdvtvkslseeekktyierkfkleresgetreveqlayta-WPdhGvPattke IIKMIHQFLSEKQV-QNAGVCVVSLFGCGRACSFIGALYAINQLNNGIEP-NICEIMKNIKQQRPGGVESFAQYASIYAIVFDYI .. .. |. .. ..| ... | ||. ..|. ....... |. ............| | . .||. .| .| |.. llefrkavlkatkkktkaplvihCsaGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavldal |
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| Phosphatase | F57H12.5.AA | Subfamily.N_Nematode_1.PD | 300-502 | 19 | 1.6e-12 | 38.1 | In-house | 59-264 (265) | Show / Hide |
Range on Protein: 300-502 Range on HMM: 59-264/265 Sequence Identity: 19% (42 aa) YFVIFQFEHKLIVAQLPQmenESFVEDFWYMIYQEQIHLVYLMVP-DDKLKNTTTSLFNDENGG-YQYTG---KMFI-NNRRADV-SGDPK---EYTIEV | . ...| || | .. ..|||||..||.. . .. .| | . | ..| ... |. . |. .... | . . ..|| yvgtptnpkrficaqaPl---dktiadfwymvlqekveaivmlckliekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlev LPEGNSDSVIcQVHHHAPWKHLQQPPKTLPIIkmihQFLSEKQVQNAGVCVVSLFGCGRACSFIGALYAINQLNNGIE-PNICEIMKNIKQQRPGGVESF |.. . . . | || | .. ..|.. ..... . | | ||. . .. |...| .| . ... ...|.|..|| . . ||| egaGektrkv-thyqWtdWPdrGvPpadlaal----elleavrgskgPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtd AQYASIYAIVFDYI .. ....|. aqylfvhrvllnyf |
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| Phosphatase | F57H12.5.AA | Subfamily.R_Anemone_2.PD | 308-502 | 20 | 2.7e-12 | 37.6 | In-house | 70-261 (262) | Show / Hide |
Range on Protein: 308-502
Range on HMM: 70-261/262
Sequence Identity: 20% (40 aa)
HKLIVAQLPQMENesfVEDFWYMIYQEQ-IHLVYLMVPDDKLKNTTTSLFNdENGGYQYtGKMFINNRRADVSGDPKEYTIEVLPEGNSDSVICQVHHHA
.. | .| | | .|||| |... . .| | .. | . ..| .| ||. .. . ..| ...|...... . . .|.. |
kayiatqaPlpet---iedfWrmvWeqnsavivmltqeeergkakvhryWP-skgsrsy-gklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhyt
PWKHLQQPPKTLPIIKMIHQFLSEKQVQNAGVCVV-SLFGCGRACSFIGALYAINQLNNGIEPNICEIMKNIKQQRPGGVESFAQYASIYAIVFDYI
| .. ..... | . .| ..||. || | ||. || ...... .. ...|....||. | || || .. ...
sWpdegvpesgaslldlvrqvekaqqesgagpivvhcsaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvlleal
|
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| Phosphatase | F57H12.5.AA | Subfamily.RB.PD | 302-502 | 15 | 1.2e-11 | 35.3 | In-house | 63-260 (261) | Show / Hide |
Range on Protein: 302-502 Range on HMM: 63-260/261 Sequence Identity: 15% (32 aa) VIFQFEHKLIVAQLPQMENesfVEDFWYMIYQEQIHLVYLMVP-DDKLKNTTTSLFNDENGGYQYtGKMFINNRRADVSGDPKEYTIEVLPeGNSDSVIC .. ... |..| | | |.||| |..... . . ... .| |. . ... .| |.. .. . . .... |.. . |. pgynspreyiatqGPlpet---vddfWrmvwekkssiivmltqlvEkgkekceeYWPadeepvly-Gdikvtllaekeldewvirefkiek-gkekrkvr QVHhHAPWKHLQQPPKTLPIIKMIHQFLSEKQVQ--NAGVCVVSLFGCGRACSFIGALYAINQLNNGIEPNICEIMKNIKQQRPGGVESFAQYASIYAIV | . | | || ......... .. . . .. . | | ||. || ...... ... .. .....| |. .|| |. .. |. qyh-ftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHCsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifihecl FDYI . ldll |
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| Phosphatase | F57H12.5.AA | Subfamily.N3.PD | 233-494 | 16 | 4.6e-11 | 33.2 | In-house | 18-252 (261) | Show / Hide |
Range on Protein: 233-494 Range on HMM: 18-252/261 Sequence Identity: 16% (43 aa) CNKTTEAFEANKVRNREGCPkiYDENRVQLNRpghEDVNYINASVITLTdvcrrmacVPAYvHLVvlyfvifqfeHKLIVAQLPQmenESFVEDFWYMIY .... . ...| | |. .| ||. ||.|. ....||||. . . .|. .|| . |..| | .. ..|||.|.. isaarkpenlaknryrdilp--ydatrvklke---setdyinanyvnme--------ipst-glv----------nryiatqGpl---aktakdfWqmvw QEQIHLVYLMVP-DDKLKNTTTSLFNDENGGYQYTgKMFINNRRADVSGDPKEYTIEVLPEG-NSDSVICQVHHHApWKHLQQPPKTLPIIKMIHQFLSE .....|. .. .. . . ... ... .. .. .. | . . . . . . | |. . | | . | ......... . .. eqkstlivmlttlverGrvkChqyWPetedelefg-efsvrcekedetksyvlrelvlkdketkeerkilqlqyla-WpdhgvPddsadflefvervrkl KQVQNAGVCVVSLFGCGRACSFIGALYAINQLNNGIEPNICEIMKNIKQQRPGGVESFAQYASI ... | | | ||. .| |. ... . .. .|......|| |.. .|| . rsgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtvsqykfv |
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| Phosphatase | F57H12.5.AA | Subfamily.N13.PD | 241-499 | 18 | 1.1e-10 | 32.4 | In-house | 26-255 (259) | Show / Hide |
Range on Protein: 241-499
Range on HMM: 26-255/259
Sequence Identity: 18% (48 aa)
EANKVRNREGCPkiYDENRVQLNRPGHedvnYINASVITLTdVcrrmacvpayvhlvvlyfviFQFEHKLIVAQLPQMENesfVEDFWYMIYQEQIHLVY
. .| | |. | ||| ||.|. | ||||| | .. | . |.. |..| | | |.||| |.... ... .
nkdknryrnvlP--ydetrvklgdegg----yinaslikvp-v--------------------gedeyeyiacqGPlPet---vkdfwqmvweqkaevia
LMVPDDKLKNTTTSLF--NDENGGYQYTGKMFINNRRADVSGDPKEYTIEVLPEGNSDSVICQVHHHAPWKHLQQPPKTLPIIKMIHQFLSEKQvQNAGV
. . .. . . .| . .... ... . . . ...| ..| . . . | . | .. ....... . .. ... . |
mvtlekekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt-dagPi
CVVSLFGCGRACSFIGALYAINQLNNGIEPNICEIMKNIKQQRPGGVESFAQYASIYAIVF
| ||. ..| ... ... | .. ||......|| | | . || .| ..
vvhcsaGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykail
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| Phosphatase | F57H12.5.AA | Subfamily.R_Nematode_2.PD | 307-492 | 21 | 2e-10 | 31.2 | In-house | 68-250 (261) | Show / Hide |
Range on Protein: 307-492 Range on HMM: 68-250/261 Sequence Identity: 21% (40 aa) EHKLIVAQLPqMENEsfVEDFWYMIYQEQIHL-VYLMVPDDKLKNTTTSLFNDENGGYQYTGKMFINNRRAD--VSGDPKEYTIEVLPE-GNSDSVICQV ... |..| | .|| .|||| |. ||.. | | .| |. .. | |.. |.. |.. |. .. . .. |..| . |. .. . pkrfiatqgP-lent--sedfWamviqekvekivmlcqkvekekekceeYfpletsqkldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvth HHHAPWKHLQQPPKTlpiiKMIHQFLSEKQVQNAGVCVVSLFGCGRACSFIGALYAINQLNNGIEPNICEIMKNIKQQRPGGVESFAQYA . .. | . . | . ... |. . .. . | | ||. .|||. | ..... . ..| .|.....|. |. |. yqyeeWpdrgvPksh----aelfeLlelvkksekPivvhCsaGiGRtmafigteylareveadptieltealkelrehRwkgiqtesqly |
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| Phosphatase | F57H12.5.AA | Subfamily.N14.PD | 302-502 | 19 | 7.7e-10 | 29.3 | In-house | 64-274 (275) | Show / Hide |
Range on Protein: 302-502 Range on HMM: 64-274/275 Sequence Identity: 19% (41 aa) VIFQFEHKLIVAQLPQmenESFVEDFWYMIYQEQIHLVYLMVPD-DKLKNTTTSLFNDE--NGGYQYTGKMFINNRRADVS--GDPKEYTIEVLPEGNSD .. |.. |||| |. | |.||| |.......|. .. . .. |. . . . .. . || . .. .. | . ....|| .. . svggkersyivaqgPl---eltvqdfwqmvweqgvqlivmlteeeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeer SVICQvhHHAPWKHLQQPPKTLPIIKMIHQFLSEKQV----------QNAGVCVVSLFGCGRACSFIGALYAINQLNNGIEPNICEIMKNIKQQRPGGVE |. .. | . |. . .. .... | .. .. | | . | ||. | . |. |... | .| .... ...|| |.. tvwhl--qytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvkeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvq SFAQYASIYAIVFDYI .||| .| .. |. tlaqykfvykvlikyl |
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| Phosphatase | F57H12.5.AA | Subfamily.N_Nematode_egg.PD | 308-502 | 21 | 8e-10 | 29.4 | In-house | 69-256 (257) | Show / Hide |
Range on Protein: 308-502 Range on HMM: 69-256/257 Sequence Identity: 21% (41 aa) HKLIVAQLPqMENEsfVEDFWYMIYQEQIHLVYLMVPDDKLKNTTTSLFNDENGGYQY-TGKMFINNRRADVSGDPKeYTIEVLP-EGNSDSVICQVHHH ..|.|| | . | ||||| |..||... . .. . .. . |. .. | . |.| . | || ...| | | | . nefilaqap-lknt--vedfwrmvfqekvqyivmltsakeserceyywpkaeseslvtvpGslrienlkvdskadpl-frvtklklvGgddeelflehwq APWKHLQQPPKTLPIIKMIHQflsekqvQNAGVCVVSLFGCGRACSFIGALYAINQLNNG--IEPNICEIMKNIKQQRPGGVESFAQYASIYAIVFDYI ..| . | ..... . | | . |. .|.... . |. .| |. . .. ....|. ||| .| .| .| .| gdvnylsdvysplrvlrklrn-------lskpvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlffi |
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| Phosphatase | F57H12.5.AA | Subfamily.RN.PD | 239-499 | 20 | 1.2e-09 | 28.7 | In-house | 23-260 (264) | Show / Hide |
Range on Protein: 239-499 Range on HMM: 23-260/264 Sequence Identity: 20% (53 aa) AFEANKVRNREGCPKIYDENRVQLNRP-GHEDVNYINASVITLTDvcRRMacvPAYvhlvvlyfvifqfehklIVAQLPQMeneSFVEDFWYMIYQEQIH | | .||. ||..||.|.. .|. .|||||.|. .| |. ||| | .| | | . ||| |.... . .. kaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhd--pra---pay-----------------iatqgpls---stiadfwqmvweqGvv LVYLMVPDDKLKNTTTSLFNDENGGYQYtGKMFINNRRADVSGDP---KEYTIEVLPEgNSDSVICQVHhHAPWKHLQQPPKTLPIIKMIHQFLSEKQVQ . . .. . .. . ..| | . .. . | . . . | . . | | . |.. . |... ..... . . . . vivnltrleeegvkqckrywpdeGsevy-hiyevhlvsehiwcddylvrsfylknlqt-setrtvtqfh-flswpeegvPasaksllefrrkvnksyrGr NAGVCVVSLFGCGRACSFIGALYAINQLNNGI-EPNICEIMKNIKQQRPGGVESFAQYASIYAIVF . | . |.||. .| ...|..|. | .|. .. ...|||| |.. .|. ... | scpivvhcsdGaGrtGvyilidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltava |
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| Phosphatase | F57H12.5.AA | Subfamily.N_Choan_2.PD | 259-502 | 16 | 1.3e-08 | 25.2 | In-house | 37-265 (266) | Show / Hide |
Range on Protein: 259-502 Range on HMM: 37-265/266 Sequence Identity: 16% (43 aa) RVQLNRPGHE-DVNYINASVITltdvcrrmacvpayvhlvvlyfvIFQF-EHKLIVAQLPQmenESFVEDFWYMIYQEQIHLVyLMVP--DDKLKNTTTS ||.|.. .. .|||| . |. ..| | |. |. .. ...|| ||..|. . . .|..| .. . RvrleeleedsataYinAnyvr-----------------------GfdgekkkYiaamgPl---pttlksfwrmiweekvtai-vmttgleEkgrkkCer LFNDENGGYQYTGKMFINNRRADVSGDP--KEYTIEVLPEGNSDSVIcqVHHHAPWKHLQQPP------KTLPIIKMIHQFLSEKQ-VQNA-GVCVVSLF |.. . ...|. . . . ... .|.. .. ... | | .| ..||... .. ...| . | | || YWpaepkekvkladgkikvlalseekeegyiltrlrlekkgetrrlv--HfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsa GCGRACSFIGALYAINQLNNGIEPNICEIMKNIKQQRPGGVESFAQYASIYAIVFDYI . .| .|.. |.. . .. .|.......|. |. ||. .|. | .|. GvgRtGtliaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavveya |
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| Phosphatase | F57H12.5.AA | Subfamily.R_Ecdysozoa.PD | 223-279 | 38 | 8.9e-07 | 19.2 | In-house | 4-64 (269) | Show / Hide |
Range on Protein: 223-279 Range on HMM: 4-64/269 Sequence Identity: 38% (23 aa) EEFGFLD-SLVCNKTTEA--FEANKVRNREGCPKIYDENRVQLNR-PGHEDVNYINASVIT ||. |. .| ..|.|.. . |...|| | .|..||.|.. .|.|| .||||| | eeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfik |
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| Phosphatase | F57H12.5.AA | Subfamily.N9.PD | 322-501 | 16 | 9.4e-07 | 19.4 | In-house | 80-273 (275) | Show / Hide |
Range on Protein: 322-501 Range on HMM: 80-273/275 Sequence Identity: 16% (31 aa) SFVEDFWYMIYQEQIHLVYLMV-PDDKLKNTTTSLFNDENGGYQYTGKMFINNRRADVSGDPKEYTIEVLPEGNSDSVICQVHHHAPWKHLQQPPKTLPI |.||| |...... . .. .. . . ...|.. . |.. ..| .|. | |. ..|. ...| . | |. ..... ktvsdfwrmvweqevlvivmttrvvergrlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaasl IKMIHQFLSE-------------KQVQNAGVCVVSLFGCGRACSFIGALYAINQLNNGIEPNICEIMKNIKQQRPGGVESFAQYASIYAIVFDY .. .. .... . | | ||. .|| .....|.. ...| .|....|| . ||. || .| ldvlekvrekqalavkelgdeskghlsgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavley |
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| Phosphatase | F57H12.5.AA | Subfamily.DSP23.PD | 415-494 | 20 | 8.8e-06 | 16.7 | In-house | 46-120 (128) | Show / Hide |
Range on Protein: 415-494 Range on HMM: 46-120/128 Sequence Identity: 20% (16 aa) PKTLPIIKMIHQFLSEKQVQNAGVCVVSLFGCGRACSFIgALYAINQLNNGIEPNICEimknIKQQRPGGVESFAQYASI | .| .. . . . | . .. | | . |.||. ... | | ... . . | | ....|.| .|. | . PPaleqvarlvriveeaekkeeavgvhcalGlGrtGtll-acylvkeeglaaddaiae----vrkrrkGsietveqekav |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| F57H12.5.AA | Protein | None | 543 | None | Fasta, JSON |
| F57H12.5.NA | RNA | None | 1629 | None | Fasta, JSON |
| F57H12.5.AA.PD_220-503 | Protein Phosphatase Domain | None | 284 | None | Fasta, JSON |