Gene Y18H1A.1
Y18H1A.1
Species: C.elegans
Alias: Y18H1A.1
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of Y18H1A.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | Y18H1A.1.AA | PTPc | 127-378 | 20 | 7.5e-39 | 136.31 | SMART | 1-308 (308) | Show / Hide |
Range on Protein: 127-378 Range on HMM: 1-308/308 Sequence Identity: 20% (64 aa) EVKKEYDKLQSQKIDV---------EKDCKTWKSNP--KFNQSE-DFPALDSNLVKLGK-----------DYVNISLVDVPLGRNVHLG-QAPVTNTEET ...|...||..... ...| |. |. . |.. | |. |.. ||| . ||.| . .|.. ... |.| .| | GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED FWKAVFDKRITHIDLLVGDET--------------IEFFPKKAEDYTNYGQMWINNRRVEYVNDDVYRFAIEVVPHGC--------SNSIICNVTVISNW ||. |.. ... | |. .. ..| . . .||.........| ..||. . .|| ..|| |.. .. . || FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE---PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNW KVDTVP---------LKQAIAIKEAL---------GLNYFLLKAPADEHAMIVSPRGAGRAGYFLALAVAVNTIDTKLAEPCIADIVKSIRSQRPRAVDS . || ..| . .. . ... . .. ... .... |.||.| |.|. .... |.. . | .|||..|.||| .|.. PDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNS-KYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN----VDIFQIVKMMRNQRPGMVQT FCQYCSLYISLLYFIK ..|| ..| .|..|| EEQYIFCYRCILEYIK |
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| Phosphatase | Y18H1A.1.AA | Subfamily.N_Nematode_5.PD | 128-378 | 40 | 1.1e-82 | 268.0 | In-house | 2-258 (258) | Show / Hide |
Range on Protein: 128-378 Range on HMM: 2-258/258 Sequence Identity: 40% (104 aa) VKKEYDKLQSQKIDVEkDCKTWKSNPKFNQSEDFPALDSNLVKLG---KDYVNISLVDVP-LGRNVHLGQAPVTNTEETFWKAVFDKRITHIDLLVGDET .|.|..||.| |...| .||....| | |.|.|.. ||...|||. ..|.|.| .... | ....|.| |...|||.||..|....||.. |||.||. lktefeklaslkpnke-tckafeknlkknrskdvkilDetrVkltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllvedee I-----EFFPKKAEDYTNYGQMWINNRRVEYVNDDVYRFAIEVVPHGCSNSIICNVTVISNWKVDTVPLKQAIAIKeaLGLNYFLLKAPAD-EHAMIVSP . .|||....||.|.|.|.||||.|| ..|. .. .||.|.|||.|....|.....|| ..|||.. .|| . .. .| | .. .....|| lketavsffpletgdylnlgkmfinnrkvevkedekkeytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvik--raiekvlskkqgknapvvvvsd RGAGRAGYFLALAVAVNTIDTKlAEPCIADIVKSIRSQRPRAVDSFCQYCSLYISLLYFIK |.||||.||.|.||....... .||.|..|.|.||||||.||.|..||.|.|...|..|| lGlgRagtflllsvaieqlnng-kepnideilkkirsqRpgavesliqyasvyaavldyik |
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| Phosphatase | Y18H1A.1.AA | Y_phosphatase | 152-375 | 22 | 2.2e-28 | 100.97 | Pfam | 1-243 (243) | Show / Hide |
Range on Protein: 152-375 Range on HMM: 1-243/243 Sequence Identity: 22% (56 aa) NPKFNQSEDFPALDSNLVKLG-------KDYVNISLVDVP--LGRNVHLGQAPVTNTEETFWKAVFDKRITHI-----DLLVGD-ET--IEFFPK-KAED |.. |.. | |..|.. |||. ||.| . .|.| ... . |.| .| | ||. |.. ..| | . |. | ...| | .. NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ YTNYGQMWINNRRVEYVNDDVYRFAIEVVPHGCSN-----SIICNVTVISNWKVDTVPLKQAIAIKEALGLNYFLLKAPA--DEH---AMIVSPRGAGRA . .|| ........| . ... . . . . .. . ||. . || . | | . . |.. | .... |.||. PMTYGDFQVTCVSEEH----CPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPES---QPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRT GYFLALAVAVNTIDTKLAEPCIADIVKSIRSQRPRAVDSFCQYCSLYISLLY | | |. .. .... | .|||..|.||| .|... ||. .| .|. GTFCAIDIMCQQMEHEGTV-DIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE |
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| Phosphatase | Y18H1A.1.AA | Subfamily.R_Anemone_1.PD | 129-374 | 24 | 3.5e-18 | 57.1 | In-house | 3-254 (258) | Show / Hide |
Range on Protein: 129-374
Range on HMM: 3-254/258
Sequence Identity: 24% (62 aa)
KKEYDKLQsQKIDVEKDCKTWKSNPKFNQSEDFPALDSNLVKLGK-------DYVNISLVDVPLGRNVH-LGQAPVTNTEETFWKAVFDKRITHIDLLVG
..|...|. .. ..||.. ..| | |. .| |||. | | | ||.| | ... ... . . |||...| | ||.|....|. | .| .
aaefqrlk-eikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLtn
D------ETIEFFPKkaeDYTNYGQMWINNRRVEYVNDDVYR-FAIEVVPHGcSNSIICNVTVIsNWKVDTVPLKQaIAIkeaLGLNYFL-LKAPADEHA
.. ...|. ..||.. .. |. | | . | .... . . .. ..... . .|.|| .. |. ||| . . |......|
liegekkkchqYwPd---stekygelrvslrkkevfadyiirtlvlskkket-eerevvqyhft-vWpdkgvPqya-tav---Lglrrkvqksslagarp
MIVS-PRGAGRAGYFLALAVAVNTIDTKLAePCIADIVKSIRSQRPRAVDSFCQYCSLYISLL
| ||.| ||.. .. . .. | ..||.||..||..|.. ||.. .|
vvvhCsaGvgRtGaflvidamleqakkekv-vDifnyvkairedrphmvqtkeqyvfihlavl
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| Phosphatase | Y18H1A.1.AA | Subfamily.N_Choan_1.PD | 153-375 | 17 | 4.9e-15 | 46.6 | In-house | 27-259 (262) | Show / Hide |
Range on Protein: 153-375 Range on HMM: 27-259/262 Sequence Identity: 17% (42 aa) PKFNQSEDFPALDSNLVKL-------GKDYVNISLVDVPLGRN-VHLGQAPVTNTEETFWKAVFDKRITHIDLLVGD---ETI---EFFPKKAeDYTNYG . |. .. | | ||. ||.| . |. | . |.|| .. ..||. |...... | .. . . ...| .. ...|.. .. vlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvtreieagklkChryWPden-selklg QMWINNRRVEYVNDDVYRfAIEVVPHGCSNSIICNVTViSNWKVDTVPLKQAiaikEALGLNYFL--LKAPADEHAMIV-SPRGAGRAGYFLALAVAVNT . . | . . | ... ... . . ... .| || . . | |. . .. . ...... | ||.| ..|| .|.....|. dvtvkslseeekktyier-kfkleresgetreveqlay-taWPdhGvPattk----ellefrkavlkatkkktkaplvihCsaGvGrtGtyialDrlvka IDTKLAEPCIADIVKSIRSQRPRAVDSFCQYCSLYISLLY .. . ..|...| .| | . || .| .| veekaealdvkavvaelrkernlmvqtlvqyefvykavld |
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| Phosphatase | Y18H1A.1.AA | Subfamily.R_Sponge_2.PD | 149-371 | 20 | 9.4e-15 | 45.7 | In-house | 22-255 (262) | Show / Hide |
Range on Protein: 149-371 Range on HMM: 22-255/262 Sequence Identity: 20% (48 aa) WKSNPKFNQSEDFPALDSNLVKLGK------DYVNISLVDVPLGRNVHL-GQAPVTNTEETFWKAVFDKRITHIDLLVG------DETIEFFPKKAEDYT |.| | .. ..|.. |.| . ||.| | ||. |. .. |.|...| | ||. |.. ....| .|. ... ...|.| .. .. lkenvgKnRfkeilpydmsRvrLrtdgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnleengkekcakYWPekvdeev NYGQMWINNRRVEYVNDDVYR-FAIEVVPHGCSNSIICNVtVISNWKVDTVPLKQAIAIKEALGLNYflLKAPADEHAMIVSPR-GAGRAGYFLALAVAV ||.. .. . | ..| . | . . .. . . .| . || .... .. .. ...|..| . |.||.| |.|| . .. ... eygkfkvtlkeeekladyiirklklskekssegeadvtqf-hfvaWpehevPkdatsllelikrvlr--aqkksgnkaitvvCsdgvgrtGtfialdsvl NTIDTKlAEPCIADIVKSIRSQRPRAVDSFCQYCSLYI | . ...|..|..|. |. || .. erlkae-eeidvfevlktlrtkriglvqdaaqYvfihd |
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| Phosphatase | Y18H1A.1.AA | Subfamily.N13.PD | 129-376 | 21 | 3.1e-14 | 44.0 | In-house | 3-257 (259) | Show / Hide |
Range on Protein: 129-376 Range on HMM: 3-257/259 Sequence Identity: 21% (55 aa) KKEYDKLQSQKIDVEKDCKTWKSNPKFNQSEDFPALDSNLVKLGKD--YVNISLVDVPLGRNVH---LGQAPVTNTEETFWKAVFDKRITHIDLLVGDET ..|...|. | . . |.| . |. . | ||||.. |.| ||. ||.| . . . | |. .| . ||. |.... . |.. . aeefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdeggyinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtleke ---I---EFFPKKAEDYTNY-GQMWINNRRVEYVNDDVYRfAIEVVPHGCSNSIICNVTVISNWKVDTVPLKQAIAIKEALGLNYFllKApaDEHAMIVS . ..|..... . ... ... .|. .. | | |..| ..|. .| || . | .. . .. .. |. ..| kgkvkchrywPerknkklkvsnrlevellkvqkldgfvvr-alavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrll--qt--dagPivvh -PRGAGRAGYFLALAVAVNTIDTKLaEPCIADIVKSIRSQRPRAVDSFCQYCSLYISLLYF | ||.| .... |... |. . | . .||...| || | . || | ..|. csaGiGrsGvlitidvvlglierdk-efdvkeivrklreqrqgvvqtkdqyifvykailev |
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| Phosphatase | Y18H1A.1.AA | Subfamily.RK.PD | 128-373 | 23 | 5.7e-14 | 42.8 | In-house | 2-262 (267) | Show / Hide |
Range on Protein: 128-373
Range on HMM: 2-262/267
Sequence Identity: 23% (60 aa)
VKKEYDKLQSQKIDV---EKDCKTWKSNPKFNQSEDFPALDSNLVKLG------KDYVNISLVDVPLGRNVH-LGQAPVTNTEETFWKAVFDKRITHIDL
.|.|.. |.| .. . | . ..| . |.|.| |.| ||.| ||.| .|.| . . | |. .| . ||. |.|... | .|
lkeefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgdssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivm
LVGD-------ETIEFFPKKAEdyTNYGQMWINNRRVEYVNDDVYR-FAIEVVPHGCSNSIICNVTVISNWKVD-TVPLKQAIAIKEALGLNYflLKAPA
. ....|...| ..||.. .. ..| .| | | |..| . .| .. . . .| || .. .|.. .....| .
lteldvevgrvkClkyWPedte--vrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkk--sqeee
DEHAMIV-SPRGAGRAGYFLALAVAVNTIDTKLAEpCIADIVKSIRSQRPRAVDSFCQYCSLYISL
.| ||||.| |.|... .. |... . .||..|.... |. || .|
eeGrivvhClaGaGrsGtfiaidivlemieregvv-dvfnavktlrnrkvnmveteeqykfvydvi
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| Phosphatase | Y18H1A.1.AA | Subfamily.R_Ecdysozoa.PD | 129-375 | 25 | 2.5e-13 | 40.7 | In-house | 3-266 (269) | Show / Hide |
Range on Protein: 129-375 Range on HMM: 3-266/269 Sequence Identity: 25% (67 aa) KKEYDKLQSQ-KIDVEKDCKTWKSNPKFNQSEDFPALDSNLVKLGK-------DYVNISLVDVPLGRN-VHLGQAPVTNTEETFWKAVFDKRITHIDLLV ..||.||... .|. . | | |..|| | |.. ||| | ||.| | . .. |.|| .| . ||. . .. .| | .| eeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivmls GDETIEF-FPKK--AEDYTNYGQMWINNRRVEYVNDDVYRfAIEVVPHG-CSNSIICNVT--VISNWKVDTVPLKQAIAIKEALGLNYFLLKAP----AD . . .| || ..||.. .. . | .| . | ...| . .| .|. .|| |. ..| .. . . . | | . nlteknrkcakyWpiedevqygdilvklvseekhsdyiir-eldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgsr EHAMIVSPRGAGRAGYFLALAVAVNTIDTKlAEPCIADIVKSIRSQRPRAVDSFCQYCSLYISLLY .. |.||.| |.||.. .. . . . | ..|| .||||. |.|.|| || .|. sPivvhCsaGvgrsgifvaldlllqqlkae-dkvdifetvkkLrsqrnllvqsleqyvflyralad |
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| Phosphatase | Y18H1A.1.AA | Subfamily.N_Nematode_4.PD | 172-374 | 21 | 4.5e-13 | 40.1 | In-house | 51-260 (264) | Show / Hide |
Range on Protein: 172-374 Range on HMM: 51-260/264 Sequence Identity: 21% (46 aa) GKDYVNISLVDVPLGRNVHLGQAPVTNTEETFWKAVFDKRITHIDLLVG--DE----TIEFFPKKAEDYTNYGQMWINN--RRVEYVNDDVY-RFAIEVV .||. | . .| . . | |. .| . || |. .|. . .| .| ..|.| | ...|. |. ...| . | .. . . .. dndyihaswmrmPdkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypeksekvvkfGkyritlvekkeeviadvilnslkvtnt P--HGC-SNSIICNVTVISNWKVDTVPLKQAIAIKealgLNYFLLKAPADEHAMIVSPRGAGRAGYFLALAVAVNTIDTkLAEPCIADIVKSIRSQRPRA . . |. .. . .. |. .. ||. | || | . | . .. .. | ||. ... | | .| . |||. .|. | .|| ekkkdapseplvvkhvqvdwwrdqvaPldaapvik----lykavkkkkkekPivvhcsaGvGrtatlvGidyatirire-nseievldivrelramrlka VDSFCQYCSLYISLL | |. |.. |. vqshlqflfllvvli |
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| Phosphatase | Y18H1A.1.AA | Subfamily.RA.PD | 173-377 | 22 | 8e-13 | 39.3 | In-house | 55-265 (266) | Show / Hide |
Range on Protein: 173-377 Range on HMM: 55-265/266 Sequence Identity: 22% (48 aa) KDYVNISLVDVPLGRNVHL-GQAPVTNTEETFWKAVFDKRITHIDLLVG------DETIEFFPKkaEDYTNYGQMWINNRRVEY-VNDDVYRFAIEVVPH ||.| | .| .. .. | | ..| | ||. ..... . | .| . ...|. | ||.. .. . .. .. | |.. .|. . sdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativmltelkerkeekcaqywpd--eGlvtyGeirvevkdetvledytvrdflvtqlpd GCSNSIICNV--TVISNWKVDTVPLKQAIAIKeALGLNYFlLKAPADEHAMIV-SPRGAGRAGYFLALAVAVNTIDTKLAEpCIADIVKSIRSQRPRAVD . | .| || . .| | |. .|...| |.||.| |..| .. . .. . ..||..| |||. | . atrekksrlvrqfhftswpevGvpaegkGmlk-llkkvkk-lqqqsanhpivvhcsaGvGrtGtfivldavlervkaerkl-dvfeavkrlrlqrpqmvq SFCQYCSLYISLLYFI || .| || .| tleqyefiykvlleyi |
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| Phosphatase | Y18H1A.1.AA | Subfamily.N_Nematode_6.PD | 128-370 | 19 | 8.4e-13 | 39.2 | In-house | 2-245 (253) | Show / Hide |
Range on Protein: 128-370 Range on HMM: 2-245/253 Sequence Identity: 19% (50 aa) VKKEYDKlqSQKIDVEKDCKTWKSNPKFNQSEDFPALDSNLVKLGKD---YVNISLVDVP-LGRNVHLGQAPVTNTEETFWKAVFDKRITHIDLLVG--- .|||| . | .. |. .... .... |. .. . | ..|| | |. .||.. | . |||. .| | ||| .. . ...| .|.. lkkeykd--spneaseseataflkfkdrnrytniqCcdagrlkladdedfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelve ---DETIEFFPKKAEDYTNYGQMWINNRRVEYVNDDVYRFAIEVVPHGCSNSIICNVTVISNWKVDTVPLKQAIAIKealglnyfLLKAP-ADEH-AMIV . . |....| | ...... . . | . .. .. . ...| . || || . |.. ||.. |. .. kgkeksaeylsdkvGdarkitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalr--------llsvvkkdkkPivvh SPRGAGRAGYFLALAVAVNTIDTKlAEPCIADIVKSIRSQRPRAVDSFCQYCSLY | ||.| . . ...... . . |.. .| .| ||| . ||. CsaGvGrtGtlaliliilealrlp-dfqgvkdllvklreerfravqtevqylyal |
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| Phosphatase | Y18H1A.1.AA | Subfamily.N3.PD | 129-366 | 21 | 1.5e-12 | 38.2 | In-house | 3-249 (261) | Show / Hide |
Range on Protein: 129-366
Range on HMM: 3-249/261
Sequence Identity: 21% (52 aa)
KKEYDKLQSQKIDVEKDCKTWKSNPKFNQSEDFPALDSNLVKLG---KDYVNISLVDVPLGR--NV---HLGQAPVTNTEETFWKAVFDKRITHIDLLVG
.....| .| .. .. | . |. | . |. ||| .||.| . |.. . | | |...| . ||. |.....|| .|
laqfeelyrkkpglaisaarkpenlaknryrdilpydatrvklkesetdyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmltt
------DETIEFFPKkAEDYTNYGQMWINNRRVEYVNDDVYRFAIEVVPHGCSNSIICNVTVIsNWKVDTVPLKQAIAIKEALGLNYflLKAPADEHAMI
...|. || ...|.. .. .. . . |.| . . . | .. . .| .|| ..| .. ..|.. ..| .. |
lverGrvkChqyWPe-tedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqyl-aWpdhgvPddsadflefvervrk--lrsgkeePvvv
VSPRGAGRAGYFLALAVAVNTIDTKlAEPCIADIVKSIRSQRPRAVDSFCQY
||.| ...| .|. |... . . |||. .| || |.. ||
hCsaGigrtGvlilletalalieaa-epvypldivrtmrdqramlvqtvsqy
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| Phosphatase | Y18H1A.1.AA | Subfamily.RB.PD | 129-376 | 21 | 1.6e-12 | 38.3 | In-house | 3-259 (261) | Show / Hide |
Range on Protein: 129-376 Range on HMM: 3-259/261 Sequence Identity: 21% (57 aa) KKEYDKLQSQKIDVEKDCKTWKSNPKFNQSEDFPALDSNLVKL-------GKDYVNISLVDV-PLGRNVHLGQAPVTNTEETFWKAVFDKRITHIDLLV- ..||..|.. . | ... .. . | . |. . . |.. ||| ..||.| . .. |. | |. .| . ||. |..|. .| .|. seeyeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmltq ----GDETI-EFFPKKAeDYTNYGQMWINNRRVEYVNDDVYR-FAIEVvphGCSNSIICNVTVISnWKVDTVPLKQAIAIKEALGLNYFLLKAPADEHAM | | . |..|.. . ..||.. .. . ... | | |.|| | .. . .. .| | || | . .. ... |..... .. lvEkgkekceeYWPade-epvlyGdikvtllaekeldewvirefkiek---gkekrkvrqyhfts-WpdhgvPektktlldfvrtvreaiekkaskkPiv IVSPRGAGRAGYFLALAVAVNTIDTKLaEPCIADIVKSIRSQRPRAVDSFCQYCSLYISLLYF | ||.| |.|| .. |... .. .| ..|..| | . || .. || . vHCsaGvGRtGtfialdrllqaieend-yvdvfgvvaelReeRnllvqtekqyifiheclldl |
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| Phosphatase | Y18H1A.1.AA | Subfamily.RG.PD | 130-375 | 20 | 3.7e-12 | 37.1 | In-house | 4-261 (264) | Show / Hide |
Range on Protein: 130-375 Range on HMM: 4-261/264 Sequence Identity: 20% (52 aa) KEYDKLQS-QKIDVEKDCKTWKSNPKFNQSEDFPALDSNLVKL-------GKDYVNISLVDVPLG-RNVHLGQAPVTNTEETFWKAVFDKRITHIDLLVG ......|. .. |.| . . ..| . | . |... ||| ||||.| | .| .. | |...| | ||. ..... .| .| eqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivmltd -DE-----TIEFFPKKaEDYTNYGQMWINNRRVEYVNDDVY-RFAIEVVPHGCSNSIICNVTVISNWKVDTVPLKQAIAIKEALGLNYflLKAPADEHAM || . ..||| .. ..... .. . | ... . .| .. . ... . ..| ..| ... . .. ... . ... ldekgrrdedvyWPkk-deplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeea--ankeeaGPiv IVSPRGAGRAGYFLALAVAVNTIDTKLAePCIADIVKSIRSQRPRAVDSFCQYCSLYISLLY |.|||| ..|| .. .... | . ...| ||..|| | . || .| || vhdsaGvgragtyialdtllqqlekeea-vnvyqvlklirakRpglvtteEqyvfiydalle |
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| Phosphatase | Y18H1A.1.AA | Subfamily.N12.PD | 171-373 | 17 | 8.1e-12 | 35.7 | In-house | 58-265 (270) | Show / Hide |
Range on Protein: 171-373 Range on HMM: 58-265/270 Sequence Identity: 17% (37 aa) LGKDYVNISLVDVPLGRNVHL-GQAPVTNTEETFWKAVFDKRITHIDLLVGD------ETIEFFPKKAEDYTNYGQMWINNRRVEYVNDDVYRFAIEVVP |.||.| ... . |. .. |.|...| . ||. ...|... . .. ..|.. |. ...|.. ... . . |.||...| .. |. egsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryWpeegeeelefgefevtleeekavdddflirtLkvea HGCSNsIIcNVTVISNWKVDTVPLKQAIAIKEALGLNYFllKAPADEHAMIVSPRGAGRAGYFLALAVAVNTIDTKLAEPC--IADIVKSIRSQRPRAVD .. . .| || .. .. .. . . |. .. | ||.| .|. . . . .. ... . |.| ..| ||. .| . || qkesr-kv-yqfhytaWPDhgvPssaksllelielvrel--qesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvq SFCQYCSLYISL .| .. tkeqyelvykav |
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| Phosphatase | Y18H1A.1.AA | Subfamily.R_Anemone_2.PD | 164-375 | 22 | 1.1e-11 | 35.7 | In-house | 39-259 (262) | Show / Hide |
Range on Protein: 164-375 Range on HMM: 39-259/262 Sequence Identity: 22% (49 aa) LD-------SNLVKLGKDYVNISLVDVPLGRNVHL-GQAPVTNTEETFWKAVFDKRITHIDLLVGDE------TIEFFPKKaeDYTNYGQMWINNRRVEY | .. | ||.| . .| .. .. |||...| | ||. |... . | | | ..|.| ...||.. .. . .. ydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivmltqeeergkakvhryWPsk--gsrsygklvvelkeeve VNDDVYRfAIEVVPHGCSNSIICNVTVISNWKVDTVPLKQAIAIkEALGlNYFLLKAPADEHAMIVS-PRGAGRAGYFLALAVAVNTIDTKlAEPCIADI | | | ..| ...... . . .| || . | . . .. . ..........|| ||.| |.|. . .. | | . ..|| .|. lsdyvlr-sfkvkrteeeeerqvrqfhytsWpdegvpesgasll-dlvr-qvekaqqesgagpivvhcsaGvGrtGvfiavdillerikae-alvdvfqt VKSIRSQRPRAVDSFCQYCSLYISLLY ||. | || .| || vkqlreqrnlmvqtkdqyefiydvlle |
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| Phosphatase | Y18H1A.1.AA | Subfamily.N_Nematode_1.PD | 130-376 | 22 | 3.9e-11 | 33.7 | In-house | 4-263 (265) | Show / Hide |
Range on Protein: 130-376
Range on HMM: 4-263/265
Sequence Identity: 22% (58 aa)
KEYDKLQsqKIDVEKDCKTWKSNPK--FNQSEDFPALDSNLVKL-----GKDYVNISLVDVPLG-RNVHLGQAPVTNTEETFWKAVFDKRITHIDLLVG-
.|. .|. | . |. |..|.. . |. .| . || | ||| .||. | .| . |||. .| . |||. ... .| .|
defralk--kfndeekvkafkeaqeadknrykdvgcldknrvklaeeplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlckl
-----DETIEFFPKKAEDYTNYGQM----WI-NNRRVEYVNDD---VYRFAIEVVPHGCSNSIICNVTvISNWKVDTVPLKQAIAIkealglnYFLLKAP
|.|| | .. ... . . |. .|. ...| . .|| |... . ...| || . |. .| .. ... .
iekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyq-WtdWPdrGvPpadlaal-------elleavr
ADEHAMIV-SPRGAGRAGYFLALAVAVNTIDTKLAEPCIADIVKSIRSQRPRAVDSFCQYCSLYISLLYF
.| | ||.| .|.. .. . . . ..||.||.||.. . || .. || .
gskgPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvllny
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| Phosphatase | Y18H1A.1.AA | Subfamily.N_Nematode_egg.PD | 183-378 | 22 | 7.8e-11 | 32.8 | In-house | 65-257 (257) | Show / Hide |
Range on Protein: 183-378 Range on HMM: 65-257/257 Sequence Identity: 22% (44 aa) VPLGRNVHLGQAPVTNTEETFWKAVFDKRITHIDLLVGD---ETIE-FFPKKAEDYTNY--GQMWINNRRVEYVNDDVYRFAIEVVpHGCSnsiiCNVTV || . | |||. || | ||. || ... .| .| | | ..|| .. . | . |.| .|. | ..| .. | . . | kpllnefilaqaplkntvedfwrmvfqekvqyivmltsakeserceyywpkaeseslvtvpGslrienlkvdskadplfrvtklkl-vGgd----deelf ISNWKVDTVPLKQaiaIKEalGLNYFLLKAPADEHAMIVSPRGAGRAGYFLALAVAVN-TIDTKLAEPCIADIVKSIRSQRPRAVDSFCQYCSLYISLLY . | | . . |. . . . . ... . | .|. ..|. .|. .. . |. .| .|. .|.| .| .| .|.||. lehwqgdvnylsd---vys--plrvlrklrnlskpvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlf FIK fir |
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| Phosphatase | Y18H1A.1.AA | PTPc_motif | 271-375 | 21 | 8.9e-11 | 43.04 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 271-375 Range on HMM: 1-92/92 Sequence Identity: 21% (24 aa) ICNVTVISNWKVD-----TVPLKQAIAIKEALGLNYFLLKAPADEHAMIVSPRGAGRAGYFLALAVAVNTIDTKLAEPCIADIVKSIRSQRPRAVDSFCQ .... ||. || .| | . . .... |.||.| | |. .... ..| ..||..|.|||..| .. | TVHHYHYTNWPDHVEKDSGVPE---DSILEFIRHVRK--------PIVVHCSAGCGRTGTFCAIDMMMQQ-------VDIFQTVKEMRKQRPGMVQTEEQ YCSLYISLLY |. .| .|. YIFCYRCILE |
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| Phosphatase | Y18H1A.1.AA | Subfamily.R_Nematode_3.PD | 151-367 | 16 | 5.6e-09 | 26.6 | In-house | 22-256 (267) | Show / Hide |
Range on Protein: 151-367 Range on HMM: 22-256/267 Sequence Identity: 16% (36 aa) SNPKFNQSEDFPA-------LDSNLVKLGKDYVNISLVDVPLGRNVHLGQAPV--------TNTEETFWKAVFDKRITHIDLLVGDE---------TIEF . .... ...| |. .. |... ..| .| | .. | |.| .| | ||... ... ... ||..|.|.. . ... . kkvsedrrvevpllektrvvLkgygkrfkddfihAnvvecpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeeekcseY FPKKAEDYTNYGQMWINN-RRVEYVNDDVYRFAIEVvPHGCSNSIICNVTVISNWKVDTVPLKQAIAIKealgLNYFLLKAPadEHAMIVSPRGAGRAGY . . ...|| . ..| . . .. ... || .| .. |.. | |. | ... | .|.. . | .....| .. ypekvdgelkfegvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkeale----likfveksk--tpvvVHCsdGisRsat FLALAVAVNTIDTKLAEPCIADIVKSIRSQRPRAVDSFCQYC . .....|..|.||..|. . .. laaielgyqliikskgkldllslikelrkqRagaiqtelela |
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| Phosphatase | Y18H1A.1.AA | Subfamily.N23.PD | 190-373 | 17 | 5.7e-09 | 26.4 | In-house | 150-346 (350) | Show / Hide |
Range on Protein: 190-373 Range on HMM: 150-346/350 Sequence Identity: 17% (33 aa) HLGQAPVTNTEETFWKAVFDKRITHIDLLVGDETI------EFFPKKAEDYTNYGQMWINNRRVEYVNDDVyRFAIEVVPHGCSNS-IICNVtVISNWKV |.|...| ||. |.... | .|. .. ...|.. .. ...|.. . .... . . . ... . | .|... .| . || iatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslkslrssegwi-ervlhlqhndvstvrlvchl-htttWse DTVPL--KQAIAIKEALGLNY---FLLKA-PADEHAMIVS-PRGAGRAGYFLALAVAVNTIDTKLAEPCIADIVKSIRSQRPRAVDSFCQYCSLY-ISL .. .|. .. | .. . .. .|. | ||.| | . |.. .... . | ..|. .| || |.. || ..| iGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagngiiniprvvrrlrqqRkymvqkkvilkklyeavl |
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| Phosphatase | Y18H1A.1.AA | Subfamily.N9.PD | 128-376 | 19 | 6.9e-09 | 26.5 | In-house | 2-273 (275) | Show / Hide |
Range on Protein: 128-376
Range on HMM: 2-273/275
Sequence Identity: 19% (53 aa)
VKKEYDKLQSQKIDVEKDCKTWKSNPKFNQSEDFPALDSNLVKLG-------KDYVNISLVDVPLGRNVHL-GQAPVTNTEETFWKAVFDKRITHIDLLV
..||| ....... . .. ..| . |. .| .|. ||| ||.| . || .. .. | |. .| . ||. |.....| .
lskeyadirnepveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmtt
G------DETIEFFPKKAEDYTNYGQMWINNRRVEYVNDDVY-RFAIEVVPHGCSNSIIC-NVTVISNWKV-----DTVPLKQAIAIKEALGLNYFL--L
...|.. |. ...|.. ..| || .| . . |. | .. | ... .. .. | . . ..... ||| ... | .
rvvergrlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdes
KAPADEHAMIV-SPRGAGRAGYFLALAVAVNTIDTkLAEPCIADIVKSIRSQRPRAVDSFCQYCSLYISLLYF
... ..| | ||.| | .| .... ... .. . . || .|.|| .. || |...| .
kghlsgPPivvhcsaGiGrtGtfitldiclarlee-vgtvdvvetvkllrtqrafsiqtpeqyefcylavley
|
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| Phosphatase | Y18H1A.1.AA | Subfamily.R_Nematode_2.PD | 192-376 | 18 | 1.4e-08 | 25.2 | In-house | 74-259 (261) | Show / Hide |
Range on Protein: 192-376
Range on HMM: 74-259/261
Sequence Identity: 18% (34 aa)
GQAPVTNTEETFWKAVFDKRITHIDLLVG------DETIEFFPKKAEDYTNYGQMWINNRRVEY-VNDDVYRFAIEVVPHGC-SNSIICNVTVISNWKVD
|.|..|| | || | . . .| .| . |.|| . .. .. |.. |.. .|. ..|.... ...|... . ..| || .
tqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdr
TVPLKQaiaikealgL-NYFLLKAPAD--EHAMIVSPRGAGRAGYFLALAVAVNTIDTkLAEPCIADIVKSIRSQRPRAVDSFCQYCSLYISLLYF
. . ||.. . . .. . | ||.. |.. .. . . . . ....| .|..|. .. |. | ...||
gvPksh---------aelfeLlelvkksekPivvhCsaGiGRtmafigteylarevea-dptieltealkelrehRwkgiqtesqlywltlgalyr
|
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| Phosphatase | Y18H1A.1.AA | Subfamily.N5_RR.PD | 192-376 | 19 | 1.7e-08 | 25.1 | In-house | 73-263 (265) | Show / Hide |
Range on Protein: 192-376 Range on HMM: 73-263/265 Sequence Identity: 19% (36 aa) GQAPVTNTEETFWKAVFDKRITHIDLLVG----D--ETIEFFPKKAED--YTNYGQMWINNRRVeyVNDDVYRFAIEVVPHGCSNSIICNVTVISNWKVD | |..|| . ||. .. .... | .| . ..||.. . .||.. |... . |. . |. |. . . . ...| .| . tqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdaedyeiserygdveikveei--verndysvrklvlkylerversvkhywytdWPdh TVPLKQAIAIKEALGLNYFLLKAPADEHA-MIVSPRGAGRAGYFLALAVAVNTIDTKLAePCIADIVKSIRSQRPRAVDSFCQYCSLYISLLYF .. | . .. | .. | ||.| |.| .||. .. . . || .| .| |..|| .. | . ksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiaisiavrqlreeiv-vdvlkivcnlrldrGGmvqtseqyelihralcly |
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| Phosphatase | Y18H1A.1.AA | Subfamily.N14.PD | 128-244 | 19 | 2.4e-08 | 24.5 | In-house | 2-135 (275) | Show / Hide |
Range on Protein: 128-244 Range on HMM: 2-135/275 Sequence Identity: 19% (26 aa) VKKEYDKLQSQKIDVEKDCKTWKSNPKFNQSEDFPALDSNLVKLG------KDYVNISLVDVPLGRNV---HLGQAPVTNTEETFWKAVFDKRITHIDLL | .||.... .. | . .. . . | . |. .|. . | |.| ..|.| | . |..| . |.|. .| . ||. |..... | .| vfteyeripkkredallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivml VGD------ETIEFFPKK--AEDYTNYGQMWINN . .....||. .. ..|. . . teeeedgkeksfkylPkleskkktvefgkfkvtt |
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| Phosphatase | Y18H1A.1.AA | Subfamily.N1.PD | 136-218 | 26 | 6.6e-08 | 23.2 | In-house | 12-98 (268) | Show / Hide |
Range on Protein: 136-218 Range on HMM: 12-98/268 Sequence Identity: 26% (23 aa) QSQKIDVEKDCKTWKSNPKFNQSEDFPALDSNLVKLG---KDYVNISLVDVP-LGRNVHLGQAPVTNTEETFWKAVFDKRITHIDLL .|.. ..|. ..| ..|. | | .|| .||.| |||... ..|. | | |...| . ||. |... . .| eskekeletreaklpenrglnryrdvspydhsrikleradvdyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimL |
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| Phosphatase | Y18H1A.1.AA | Subfamily.N_Choan_2.PD | 192-377 | 16 | 8.8e-08 | 22.5 | In-house | 70-265 (266) | Show / Hide |
Range on Protein: 192-377 Range on HMM: 70-265/266 Sequence Identity: 16% (31 aa) GQAPVTNTEETFWKAVFDKRITHIDLLVG------DETIEFFPKKAEDYTNYGQMWINNRRVEYVNDDVYRFA-IEVVPHGCSNSIIcnVTVISNWKVDT ..|. .| ..||. ..... | | .. | .. ..|..... ... .. |. . .. .... |.. ... .| .....| ..|| .. .. amgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkladgkikvlalseekeegyiltrlrlekkgetrrlv--HfwyntWpdhg VPLKQAIAIKeALGLNYFLLKAPADEH-------AMIVSPRGAGRAGYFLALAVAVNTIDTKLAEPCiADIVKSIRSQRPRAVDSFCQYCSLYISLLYFI . . | . | . . .. .. | ||.| ..|. ||...... . . |...| .|. |. || || ... .. vpreedssls-tdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtliaiDiavrlLeetkkvdv-laiieelRkdRmalvqhpeqyellykavveya |
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| Phosphatase | Y18H1A.1.AA | Subfamily.RC.PD | 170-372 | 22 | 1.6e-07 | 21.8 | In-house | 70-282 (288) | Show / Hide |
Range on Protein: 170-372 Range on HMM: 70-282/288 Sequence Identity: 22% (47 aa) KLGKDYVNISLVDVPLGRNVH-LGQAPVTNTEETFWKAVFDKRITHIDLLV----GDETI--EFFpkkAEDYTNYGQMWINNRRVEYVNDDVYRfAIEVV . | .|.| | .| .. | | .| . ||. .|..... | .| ||. . |.. | ||.. .. . . .| . |.|.| . eegskyinasfidsykkpekyiaaqGplketvddfwrmiferkvkvivmltelkeGdrekcaeyw---eeGkrayGdvevdlkdtdkssdyilr-klelv PHGCSNSIICNVTVISNWKVDTVPLKQAIAIKEALGLNYFLL-KA--PA-----DEHAMIVSPRGAGRAGYFLALAVAVNTIDTKLaEPCIADIVKSIRS .| ..| |. .| . .| .. | | | .. |..|.| |.|| ........ ..|| .| .|| |. nkkrkdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaee-kvdvfqvvkklrk QRPRAVDSFCQYCSLYIS . || || arplmvsveeqyillydv |
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| Phosphatase | Y18H1A.1.AA | Subfamily.N20.PD | 130-371 | 25 | 6.5e-07 | 20.1 | In-house | 4-250 (257) | Show / Hide |
Range on Protein: 130-371 Range on HMM: 4-250/257 Sequence Identity: 25% (62 aa) KEYDKLQSQKIDVEKDCKTWKSNPKFNQSEDFPALDSNLVKLG--KDYVNISLVDV-PLGRNVH--LGQAPVTNTEETFWKAVFDKRITHIDLLVGDetI .|. |. ... | .. || . |. | || | || |||.| | . . | . | |. .| . ||. |... | .. . | qefmalelknlpgefnsgnqpsnreknryrdilpydstrvplgkskdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitre--i EFFPKKAEDYTNY---GQMWINNRRVEYVNDDVYRFAI----EVVPHGCSNSIICNVTVISNWKVDTVPLKQAIAIKEALGLNYFLLKAPadehAMIVSP | |. | . .. || | .. .. | .|| . | . ...| | ||| | .. | ||.| | eggiikcyhywpislkkplelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarkshltgp----mvvhcs RGAGRAGYFLALAVAVNTIdTKLAEPCIADIVKSIRSQRPRAVDSFCQYCSLYI |.. | . .| | . | ||| .| || |.. || | agigrtgvflcvdvvfcai-vkncsfnimdivaqmreqrsgmvqtkeqyhfcyd |
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| Phosphatase | Y18H1A.1.AA | Subfamily.N6.PD | 165-378 | 17 | 1.3e-06 | 18.9 | In-house | 53-295 (295) | Show / Hide |
Range on Protein: 165-378 Range on HMM: 53-295/295 Sequence Identity: 17% (43 aa) DSNLVK--------LGKDYVNISLVDVP-----LGRNVHLG---------QAPVTNTEETFWKAVFDKRITHIDLLV-----G-DETIEFFPKKAEDYTn | . |. |.||.| . ...| | ||. | ....| . ||. |... . | .. | . . ..|.... . . DhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdFWrmvwqensrvivmttkevergknkCarYWPdeetkke- YGQMWINNRRVEYVNDDVY-RFAIEVV-PHGCSNSiICNVtVISNWKVDTVPLKQAIAIKEALGLNYFLLKAPADEHAMIVSPRGAGRAGYFLALAVAVN |.. ... . . .| . .| .. . .. . | . .| || .. . .. .| . .. | ||.| |. . . ... tGvitvtsisEkstadYtlRefsvshkdkdkeare-ifqy-hfkaWPdhgvpkdpgvvlnfledvnkkqeelekagpivvhcsaGiGrtGtfividivlk TIDTKLAEPCI--ADIVKSIRSQRPRAVDSFCQYCSLYISLLYFIK | .. .. | ..|..|||| . | . || .|. . ..|. iieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqfyie |
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| Phosphatase | Y18H1A.1.AA | Subfamily.N14.PD | 317-378 | 26 | 9.8e-06 | 15.9 | In-house | 215-275 (275) | Show / Hide |
Range on Protein: 317-378 Range on HMM: 215-275/275 Sequence Identity: 26% (16 aa) PRGAGRAGYFLALAVAVNTIDTKlAEPCIADIVKSIRSQRPRAVDSFCQYCSLYISLLYFIK |.||.| . . ..|... | | ... .| || |....|| .| |. ..| saGvGrtGvlilsdlliatlehn-eeidikkvlarLrkqrmllvqtlaqykfvykvlikylk |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| Y18H1A.1.AA | Protein | None | 425 | None | Fasta, JSON |
| Y18H1A.1.NA | RNA | None | 1275 | None | Fasta, JSON |
| Y18H1A.1.AA.PD_127-378 | Protein Phosphatase Domain | None | 252 | None | Fasta, JSON |