Y57G11C.6
Species: C.elegans
Alias: Y57G11C.6
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: N_Nematode_5
Protein domain

Protein domains of Y57G11C.6.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase Y57G11C.6.AA PTPc 184-435 20 4.6e-38 133.69 SMART 1-308 (308) Show / Hide
Range on Protein: 184-435
Range on HMM: 1-308/308
Sequence Identity: 20% (65 aa)

EVKKEFEKLQSMKVDV---------EKECKTWKANS--KYNQSE-DFPALDSNLLKVEK-----------DYVNISRVEIPLGRNIYIG-QVPVKDTEET
 ...|||.||.|...          ...|  |..|   . |..  | |. |..  |  .           ||.| . .... ... ||  | | ..| | 
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

FWKAVFDKRIVSIDVIVGDEP--------------IEFFPKKAEDYKNYGQMWINNRKVEYVSDDVFRFSIEVLPHGC--------SNSIICNVTVISNW
||. |.. .. .|  .. ..                 ..| .   ...||.........| ..||. .  .|| ..||        |.. .. .    ||
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE---PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNW

KVDSVP---------VKQAIAIKEAF---------GLNSYLLKAPADDNAMINSQHGAGRAGYFLALAVAVHTIDTKVAEPCIVDIVKSIRSQRPRAVDS
.  .||         ..|  . .. .         ...   .. ...   .. .  |.||.| |.|. .... |..    . | .|||..|.||| .|..
PDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNS-KYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN----VDIFQIVKMMRNQRPGMVQT

FCQYCSLYISLLYFIK
..|| ..|  .|..||
EEQYIFCYRCILEYIK

Phosphatase Y57G11C.6.AA Subfamily.N_Nematode_5.PD 185-435 39 2.9e-84 273.2 In-house 2-258 (258) Show / Hide
Range on Protein: 185-435
Range on HMM: 2-258/258
Sequence Identity: 39% (103 aa)

VKKEFEKLQSMKVDVEkECKTWKANSKYNQSEDFPALDSNLLKVE---KDYVNISRVEIP-LGRNIYIGQVPVKDTEETFWKAVFDKRIVSIDVIVGDEP
.|.|||||.|.|...| .||....|.|.|.|.|.. ||....|..   ..|.|.| .... | ......|.|..||||.||..|....|.|. ..|.|| 
lktefeklaslkpnke-tckafeknlkknrskdvkilDetrVkltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllvedee

I-----EFFPKKAEDYKNYGQMWINNRKVEYVSDDVFRFSIEVLPHGCSNSIICNVTVISNWKVDSVPVKQAIAIKeaFGLNSYLLKAPAD-DNAMINSQ
.     .|||....||.|.|.|.||||||| ..|.  ....||||.|||.|....|.....|| ..|||.. .||  . ....| |  .. ..... |..
lketavsffpletgdylnlgkmfinnrkvevkedekkeytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvik--raiekvlskkqgknapvvvvsd

HGAGRAGYFLALAVAVHTIDTKvAEPCIVDIVKSIRSQRPRAVDSFCQYCSLYISLLYFIK
|.||||.||.|.||....... .||.|..|.|.||||||.||.|..||.|.|...|..|| 
lGlgRagtflllsvaieqlnng-kepnideilkkirsqRpgavesliqyasvyaavldyik

Phosphatase Y57G11C.6.AA Y_phosphatase 209-432 19 5.4e-32 113.65 Pfam 1-243 (243) Show / Hide
Range on Protein: 209-432
Range on HMM: 1-243/243
Sequence Identity: 19% (49 aa)

NSKYNQSEDFPALDSNLLKVE-------KDYVNISRVEIP--LGRNIYIGQVPVKDTEETFWKAVFDKR---IVSIDVIVGDEP-----IEFFPK-KAED
| . |.. | |..|..  |.         ||.| . ...|   ...  . | | ..| | ||. |.. .   || .  .. ..       ...|  | ..
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ

YKNYGQMWINNRKVEYVSDDVFRFSIEVLPHGCSN-----SIICNVTVISNWKVDSVPVKQAIAIKEAFGLNSYLLKAPA---DD--NAMINSQHGAGRA
...|| ........|        . .....  . .     . .. .    ||. ..||     . |  . .  .. |..    .     .. . .|.||.
PMTYGDFQVTCVSEEH----CPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPES---QPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRT

GYFLALAVAVHTIDTKVAEPCIVDIVKSIRSQRPRAVDSFCQYCSLYISLLY
| | |. .. . ....     | .|||..|.||| .|... ||. .|  .|.
GTFCAIDIMCQQMEHEGTV-DIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

Phosphatase Y57G11C.6.AA Subfamily.R_Anemone_1.PD 186-431 22 9e-18 55.7 In-house 3-254 (258) Show / Hide
Range on Protein: 186-431
Range on HMM: 3-254/258
Sequence Identity: 22% (57 aa)

KKEFEKLQSMKvDVEKECKTWKANSKYNQSEDFPALDSNLLKVEK-------DYVNISRVEIPLGRNIY-IGQVPVKDTEETFWKAVFDKRIVSIDVIVG
..||..|...| ..|||.   ..| | |. .|  |||.    .||       ||.| | ..   ... . . | |...| | ||.|....| .| .. . 
aaefqrlkeik-eeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLtn

------DEPIEFFPKkaeDYKNYGQMWINNRKVEYVSDDVFRFSIEVLPHGCSNSIICNVTVIsNWKVDSVPVKQAIAIKEAFGLNSYllKAPADDNAMI
      .  ...|.     ..||.. .. || |  .| . |  .    .  .. .....  . .|   .|| ...  ..    ...   . . .   ...
liegekkkchqYwPd---stekygelrvslrkkevfadyiirtlvlskkketeerevvqyhft-vWpdkgvPqyatavLglrrkvqks--slagarpvvv

NSQHGAGRAGYFLALAVAVHTIDTKVAePCIVDIVKSIRSQRPRAVDSFCQYCSLYISLL
   | ||.| ||..   .. . ..     | ..||.||..||..|..  ||  ..  .| 
hCsaGvgRtGaflvidamleqakkekv-vDifnyvkairedrphmvqtkeqyvfihlavl

Phosphatase Y57G11C.6.AA PTPc_motif 328-432 21 2.9e-16 61.26 SMART 1-92 (92) Show / Hide
Range on Protein: 328-432
Range on HMM: 1-92/92
Sequence Identity: 21% (24 aa)

ICNVTVISNWKVD-----SVPVKQAIAIKEAFGLNSYLLKAPADDNAMINSQHGAGRAGYFLALAVAVHTIDTKVAEPCIVDIVKSIRSQRPRAVDSFCQ
....    ||.       .||     .| | . .           . .. . .|.||.| | |. ....        ..| ..||..|.|||..| .. |
TVHHYHYTNWPDHVEKDSGVPE---DSILEFIRHVRK--------PIVVHCSAGCGRTGTFCAIDMMMQQ-------VDIFQTVKEMRKQRPGMVQTEEQ

YCSLYISLLY
|. .|  .|.
YIFCYRCILE

Phosphatase Y57G11C.6.AA Subfamily.N_Nematode_4.PD 227-431 22 1.1e-14 45.4 In-house 46-260 (264) Show / Hide
Range on Protein: 227-431
Range on HMM: 46-260/264
Sequence Identity: 22% (49 aa)

K---VEKDYVNISRVEIPlGRNIYI-GQVPVKDTEETFWKAVFDKRIVSIDVIVG--DE----PIEFFPKKAEDYKNYGQMWINN--RKVEYVSdDVFRF
|    ..||.  | . .|  .  ||  | |.|.| . ||  |.  .|  . ..    .|       ..|.| |  ...|.  |..|.| .. ||   |..
knrdpdndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypeksekvvkfGkyritlvekkeevia-dviln

SIEVLPHG----CSN-SIICNVTVISNWKVDSVPVkQAIAIKEafgLNSYLLKAPADDNAMINSQHGAGRAGYFLALAVAVHTIDtKVAEPCIVDIVKSI
|        ..   .. .   .. |. .  |. .|... .   |  .. | . .   ..    |||.  .. .  |   |   ..|  ..|||. .|. |
slkvtntekkkdapseplvvkhvqvdwwrdqvaPl-daapvik---lykavkkkkkekPivvhcsaGvGrtatlvGidyatirir-enseievldivrel

RSQRPRAVDSFCQYCSLYISLL
 .|| |  |.  |.. |.    
ramrlkavqshlqflfllvvli

Phosphatase Y57G11C.6.AA Subfamily.N_Choan_1.PD 187-432 19 1.5e-14 45.0 In-house 4-259 (262) Show / Hide
Range on Protein: 187-432
Range on HMM: 4-259/262
Sequence Identity: 19% (51 aa)

KEFEKLQSMKVDVEKECKTWKANSKYNQSEDFPALDSNLLKV-------EKDYVNISRVEIPLGRNIYI-GQVPVKDTEETFWKAVFDKRIVSIDVIVG-
.|.|||... ||   .  . ..| . |. ..  | |    ||       . ||.| . |.   | . ||  | || .. ..||. |...... | ..   
eeyeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvtre

--DEPI---EFFPKKAEdYKNYGQMWINNRKVEYVSDDVFRfSIEVLPHGCSNSIICNVTViSNWKVDSVPVKQAIAIKeaFGLNSYLLKAP-ADDNAMI
   . .    ..| ...   ..|.. ... . |  .  . |  ...  ... .  . ...   .|    || ..  ..  |  . . .. .  .   .| 
ieagklkChryWPdens-elklgdvtvkslseeekktyier-kfkleresgetreveqlay-taWPdhGvPattkelle--frkavlkatkkktkaplvi

NSQHGAGRAGYFLALAVAVHTIDTKVAEPCIVDIVKSIRSQRPRAVDSFCQYCSLYISLLY
   | ||.| ..||  .|.....|  .. . ..|...| .|   | .  ||  .|  .|  
hCsaGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavld

Phosphatase Y57G11C.6.AA Subfamily.RG.PD 186-432 21 2.1e-14 44.4 In-house 3-261 (264) Show / Hide
Range on Protein: 186-432
Range on HMM: 3-261/264
Sequence Identity: 21% (56 aa)

KKEFEKLQSMK-VDVEKECKTWKANSKYNQSEDFPALDSNLLKV-------EKDYVNISRVEIPLGRNIYI-GQVPVKDTEETFWKAVFDKRIVSIDVIV
...||..|..|  |.| |  . . |.. |   .  |...   |.       .|||.| | ..     . ||  | |.|.| | ||. .....| ..   |
eeqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivmlt

G-DE-----PIEFFPKKaEDYKNYGQMWINNRKVEYVSDDVFR-FSIEVLPHGCSNSIICNVTVISNWKVDSVPVKQAIAIKEAFglNSYLLKAPADDNA
|        ..||| ..  ..... ..  . | .|. . | |...   .  ...   .    ..|   ..| ...  . ..   ..   .  .    .. 
dldekgrrdedvyWPkk-deplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvk--keeaankeeaGPi

MINSQHGAGRAGYFLALAVAVHTIDTKVAePCIVDIVKSIRSQRPRAVDSFCQYCSLYISLLY
 ..|.|||| ..||   .. .... |   . ...| ||..||  | .  ||  .|  ||    
vvhdsaGvgragtyialdtllqqlekeea-vnvyqvlklirakRpglvtteEqyvfiydalle

Phosphatase Y57G11C.6.AA Subfamily.RK.PD 185-430 23 5.9e-14 42.7 In-house 2-262 (267) Show / Hide
Range on Protein: 185-430
Range on HMM: 2-262/267
Sequence Identity: 23% (60 aa)

VKKEFEKLQSMKVDV-EKECK--TWKANSKYNQSEDFPALDSNLLK---V---EKDYVNISRVEIPLGRNIYI-GQVPVKDTEETFWKAVFDKRIVSIDV
.|.||| |.|.  ..  ..|.  . . | . |.|.|  |.|  | .   |   . ||.| . ..     . .|  | |...| . ||. |.|..|| .. 
lkeefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgdssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivm

IVGD-------EPIEFFPKKAEdyKNYGQMWINNRKVEYVSDDVFR-FSIEVLPHGCSNSIICNVTVISNWKVD-SVPVKQAIAIKEAFGLNSYllKAP-
         . ....|...|  ..||.. ..  ..|  .| | | |..| | .| ..  . .     .|     |||..   .|...   ...  . . .
lteldvevgrvkClkyWPedte--vrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkks--qeee

ADDNAMINSQHGAGRAGYFLALAVAVHTIDTKVAEpCIVDIVKSIRSQRPRAVDSFCQYCSLYISL
.    ||||.| |.|... .  |...     .  .||..|....  |.   ||  .|         
eeGrivvhClaGaGrsGtfiaidivlemieregvv-dvfnavktlrnrkvnmveteeqykfvydvi

Phosphatase Y57G11C.6.AA Subfamily.RA.PD 186-434 22 1.1e-13 42.1 In-house 3-265 (266) Show / Hide
Range on Protein: 186-434
Range on HMM: 3-265/266
Sequence Identity: 22% (58 aa)

KKEFEKLQSMKVD-VEKECKTWKANSKYNQSEDFPALDSNLLK-------VEKDYVNISRVEIPLGRNIYI-GQVPVKDTEETFWKAVFDKRIVSIDVIV
..||.|| |.|.   . .  . ..| | |.  .    | . .         | ||.| | ..    .. .|  | | ..| | ||. ......| ..   
eeefkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativmlt

G------DEPIEFFPKkaEDYKNYGQMWINNRKVEYVSD-DVFRFSIEVLPHGCSNSIICNVT--VISNWKVDSVPVKQAIAIKEAFGLnSYLLKAPADD
     .   ...|.  |    ||.. .. .... . |  |  | .. ||. . .     |.     .|    ||..    .|.   | .  |.   ..  
elkerkeekcaqywpd--eGlvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkv-kklqqqsanh

NAMINSQHGAGRAGYFLALAVAVHTIDTKVAePCIVDIVKSIRSQRPRAVDSFCQYCSLYISLLYFI
  |.||.| |..|   .. . ..     . ..||..| |||. | .  ||  .|  || .|      
pivvhcsaGvGrtGtfivldavlervkaerk-ldvfeavkrlrlqrpqmvqtleqyefiykvlleyi

Phosphatase Y57G11C.6.AA Subfamily.R_Sponge_2.PD 227-428 19 1.5e-13 41.8 In-house 43-255 (262) Show / Hide
Range on Protein: 227-428
Range on HMM: 43-255/262
Sequence Identity: 19% (42 aa)

K------VEKDYVNISRVEIPLGRNIYI-GQVPVKDTEETFWKAVFDKRIVSIDVIVG------DEPIEFFPKKAEDYKNYGQMWINNRKVEYVSDDVFR
.       . ||.| | |.    |. ||  | |.|.| | ||. |.. .. .| ...       ..  ...|.| .. ..||.. .. .. | ..| . |
rLrtdgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnleengkekcakYWPekvdeeveygkfkvtlkeeekladyiir

-FSIEVLPHGCSNSIICNVtVISNWKVDSVPVKQAIAIKEAFGLNSYLLKApADDNAMINSQHGAGRAGYFLALAVAVHTIDTKvAEPCIVDIVKSIRSQ
 . .       ..  . .     .|  ..|| .... ..    ..    |   .   ..  ..|.||.| |.|| . .. ...   |  . ...|..|..
klklskekssegeadvtqf-hfvaWpehevPkdatsllelikrvlraqkks-gnkaitvvCsdgvgrtGtfialdsvlerlkae-eeidvfevlktlrtk

RPRAVDSFCQYCSLYI
|.  |.   ||  .. 
riglvqdaaqYvfihd

Phosphatase Y57G11C.6.AA Subfamily.N13.PD 186-433 20 1.9e-13 41.4 In-house 3-257 (259) Show / Hide
Range on Protein: 186-433
Range on HMM: 3-257/259
Sequence Identity: 20% (53 aa)

KKEFEKLQSMKVDVEKECKTWKANSKYNQSEDFPALDSNLLKVE--KDYVNISRVEIPLGRNIY---IGQVPVKDTEETFWKAVFDKRIVSIDVIVGDEP
..||..|. .|   . |    |.| . |.  .    |   .|..    |.| | ...|.| . |   . | |. .| . ||. |....   |..  .   
aeefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdeggyinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtleke

---I---EFFPKKAED-YKNYGQMWINNRKVEYVSDDVFRfSIEVLPHGCSNSIICNVTVISNWKVDSVPVKQAIAIKeafgLNSYLLKAPADDNAM-IN
  .    ..|.....  | .... ... ||.  .. | | ...|     ..|.        .|   .|| . |  ..    . ... .   |   . .  
kgkvkchrywPerknkklkvsnrlevellkvqkldgfvvr-alavkdsesgesrevahlnfvkwPdhgvPssaaelvq----fvaevrllqtdagPivvh

SQHGAGRAGYFLALAVAVHTIDTKVaEPCIVDIVKSIRSQRPRAVDSFCQYCSLYISLLYF
  | ||.| .... |..  |. .  |  . .||...| ||   | .  ||   | ..|.  
csaGiGrsGvlitidvvlglierdk-efdvkeivrklreqrqgvvqtkdqyifvykailev

Phosphatase Y57G11C.6.AA Subfamily.N3.PD 186-423 23 3.4e-13 40.3 In-house 3-249 (261) Show / Hide
Range on Protein: 186-423
Range on HMM: 3-249/261
Sequence Identity: 23% (57 aa)

KKEFEKLQSMKVDVEKECKTWKANSKYNQSEDFPALDS---NLLKVEKDYVNISRVE--IPLGR--NIYI-GQVPVKDTEETFWKAVFDKRIVSI---DV
..||.|   | ..  ..    .| . |.  |  . |.   .| . |.||.| . |.  ||     | ||  | |...| . ||. |.....|     .| 
laqfeelyrkkpglaisaarkpenlaknryrdilpydatrvklkesetdyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmltt

IV--GD-EPIEFFPKkAEDYKNYGQMWINNRKVEYVSDDVFRFSIEVLPHGCSNSIICNVTVIsNWKVDSVPVKQAIAIKEAFGLNSylLKAPADDNAMI
 |     ...|.  ||  ..|.. .. .| .  .  |.|  .    .   .  | ..  . .|   .|| ..|  ..    ...|.. ...  ..    |
lverGrvkChqyWPe-tedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqyl-aWpdhgvPddsadflefvervrk--lrsgkeePvvv

NSQHGAGRAGYFLALAVAVHTIDTKvAEPCIVDIVKSIRSQRPRAVDSFCQY
 ||.| ...| .|.. |...  .  ..|||. .| ||   |..  ||     
hCsaGigrtGvlilletalalieaa-epvypldivrtmrdqramlvqtvsqy

Phosphatase Y57G11C.6.AA Subfamily.R_Ecdysozoa.PD 186-432 23 4.6e-13 39.8 In-house 3-266 (269) Show / Hide
Range on Protein: 186-432
Range on HMM: 3-266/269
Sequence Identity: 23% (61 aa)

KKEFEKLQSM-KVDVEKECKTWKANSKYNQSEDFPALDSNLLKVE-------KDYVNISRVEIPLGRNIYI-GQVPVKDTEETFWKAVFDKRIVSIDVIV
..|.|||..  ... . .    | |   |..||  | |..  |..        ||.| | ..    .. .|  | ||. | . ||. . .. .  | .. 
eeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivmls

--GDEPIEfFPKK--AEDYKNYGQMWINNRKVEYVSDDVFR-FSIEVLP-HGCSNSIICNVTVISNWKVDSVPVKQAIAIKEAFG----LNSYLLKAPAD
  .. . .  .|    || ..||.. ..  . |  || . | ...     ..  .|         .|| ||   ..| .. .       |..   .. . 
nlteknrk-cakyWpiedevqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgsr

DNAMINSQHGAGRAGYFLALAVAVHTIDTKvAEPCIVDIVKSIRSQRPRAVDSFCQYCSLYISLLY
   ..  . |.||.| |.||.. .. . .   .  |...|| .||||.  |.|.||  || .|.  
sPivvhCsaGvgrsgifvaldlllqqlkae-dkvdifetvkkLrsqrnllvqsleqyvflyralad

Phosphatase Y57G11C.6.AA Subfamily.RB.PD 187-433 21 5.4e-13 39.8 In-house 4-259 (261) Show / Hide
Range on Protein: 187-433
Range on HMM: 4-259/261
Sequence Identity: 21% (55 aa)

KEFEKLQSMKVDVEKECKTWKANSKYNQSEDFPALDSNL-------LKVEKDYVNISRVEIPLGRNIYI-GQVPVKDTEETFWKAVFDKRIVSIDV---I
.|.|.|.... | ... .. ..|.. |. .   . |..         . ..||.| . ..    .. ||  | |...| . ||. |..|.   |.   .|
eeyeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmltql

V--GDEPI-EFFPKKAeDYKNYGQMWINNRKVEYVSDDVFR-FSIEVlphGCSNSIICNVTVISnWKVDSVPVKQAIAIKEAFGLNSYLLKAPADDNAMI
  | | . |..|..  .  .||.. ..  . . ... | | |.||    | ..  . ..  .| |   .|| | .  ..    ..... |....   .. 
vEkgkekceeYWPade-epvlyGdikvtllaekeldewvirefkiek---gkekrkvrqyhfts-WpdhgvPektktlldfvrtvreaiekkaskkPivv

NSQHGAGRAGYFLALAVAVHTIDTKVaEPCIVDIVKSIRSQRPRAVDSFCQYCSLYISLLYF
   | ||.| |.||   .. |...     .. .| ..|..|   | .  ||  ..  || . 
HCsaGvGRtGtfialdrllqaieend-yvdvfgvvaelReeRnllvqtekqyifiheclldl

Phosphatase Y57G11C.6.AA Subfamily.N14.PD 185-435 17 8.6e-13 39.0 In-house 2-275 (275) Show / Hide
Range on Protein: 185-435
Range on HMM: 2-275/275
Sequence Identity: 17% (48 aa)

VKKEFEKLQSMKVDVEKECKTWKANSKYNQSEDFPALDSNLLKV------EKDYVNISRVEIPLGRN--IYI-GQVPVKDTEETFWKAVFDKRIVSIDVI
| .|.|... .. | . .. . . | . |. .|.   . | ...      ...|.| |......| .   ||  | |.. | . ||. |....  |  . 
vfteyeripkkredallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivml

VGD------EPIEFFPKKA--EDYKNYGQMWINNRKVEYVS-DDVFRFSIEVLPHGCSNSIIcnVTVISNWKVDSVPVKQAIAIKEAFGLNSYLLKAPAD
 .        ....||.   ..  ..|.  . .. .|  .      . .. || .   ...       .|  . ||      ....|   |.    .   
teeeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvw--hlqytDWpdhgvPeDvkgflsfLeevqsvrrktnse

DN--------AMINSQHGAGRAGYFLALAVAVHTIDTKvAEPCIVDIVKSIRSQRPRAVDSFCQYCSLYISLLYFIK
      ..    |.||.|  .   . ..|...   |  |  ... .| ||   |....||  .|  |. ..|     
vesvkeskPPvlvhCsaGvGrtGvlilsdlliatlehn-eeidikkvlarLrkqrmllvqtlaqykfvykvlikylk

Phosphatase Y57G11C.6.AA Subfamily.N12.PD 222-430 18 1.8e-12 37.9 In-house 45-265 (270) Show / Hide
Range on Protein: 222-430
Range on HMM: 45-265/270
Sequence Identity: 18% (42 aa)

DSNLLK-------VEKDYVNISRVEIPLGRNIYI-GQVPVKDTEETFWKAVFDKRIVsIDVIVGDE-------PIEFFPKKAEDYKNYGQMWINNRKVEY
| . ..        ..||.| . .. . |.  ||  | |. .| . ||. ...|..  | |..  |          ..|.. |.  ..|.. ... . . 
dksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknve-ivvmaCrevelgkkkCeryWpeegeeelefgefevtleeeka

VSDDVFRFSIEVLPHGCSNSIicNVTVISNWKVDSVPVKQAIAIKEAFGLNSYLLkaPADDNAMINSQHGAGRAGYFLALAVAVHTIDTKVAEPC--IVD
|.|| .  ...|  .. |...  .     .|    || ..   ..    ....      |   ..    | ||.|  .|.  . .. ..  ...  . |.
vdddflirtLkveaqkesrkv--yqfhytaWPDhgvPssaksllelielvrelqe--sedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfd

IVKSIRSQRPRAVDSFCQYCSLYISL
| ..| ||. .| .  ||  .| .. 
lvlelrkqraalvqtkeqyelvykav

Phosphatase Y57G11C.6.AA Subfamily.N_Nematode_6.PD 186-427 20 2.1e-12 37.9 In-house 3-245 (253) Show / Hide
Range on Protein: 186-427
Range on HMM: 3-245/253
Sequence Identity: 20% (51 aa)

KKEFEKlqSMKVDVEKECKTWKANSKYNQSEDFPALDSNLLKVEKD---YVNISRVEIPLG-RNIYIGQVPVKDTEETFWKAVFDKRIVSIDVI---V--
|||...  | .   |.|.... .... |. .. .  |  .||.. |   |.  ..|.|    | .   | |...| | ||| ... . .| ..   |  |
kkeykd--spneaseseataflkfkdrnrytniqCcdagrlkladdedfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelvek

G-DEPIEFFPKKAEDYKNYGQMWINNRKVEYVSDDVFRFSIEVLPHGCSNSIICNVTVISNWKVDSVPVKqaiaIKEAFGLNSYLLKapADDNAMINSQH
 .   |....|  | ......    .  .   | .   |. .. .   ...| .     ||    ||.    .. |. | | . |       ..    | 
gkeksaeylsdkvGdarkitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPds----flsalrllsvvkk--dkkPivvhCsa

GAGRAGYFLALAVAVHTIDtKVAEPCIVDIVKSIRSQRPRAVDSFCQYCSLY
||.| .  . ......  ..    . |..  .| .| |||  . ||   .  
GvGrtGtlaliliilealr-lpdfqgvkdllvklreerfravqtevqylyal

Phosphatase Y57G11C.6.AA Subfamily.N_Nematode_egg.PD 212-435 21 3.6e-12 37.1 In-house 34-257 (257) Show / Hide
Range on Protein: 212-435
Range on HMM: 34-257/257
Sequence Identity: 21% (48 aa)

YNQSEDFPALDSNLL--KVEKDYVNISRVE-IPLGRNIYIGQVPVKDTEETFWKAVFDKR---IVSIDVIVGDEPIEF-FPKKAEDYKNY--GQMWINNR
. ...  .  .|   .   |..   ||.  ||  .. . | |.|.| | ||. || ..   || ..  .  |  |. .||..   .  | . |.| ||. 
rvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmltsakeserceyywpkaeseslvtvpGslrienl

KVEYVSDDVFRFSIEVLpHGCSnsiiCNVTVISNWKVDsvpVKQAIAIKEAFGLnsYLLKAPADDNAMINSQHGAGRAGYFLALAVAV-HTIDTKVAEPC
 .| .|| .   |  |       .   .  |. |   |...  .   . .    .   ....... |  .|. ..|. .|. . .   .    .   |. 
kvdskadplfrvtklkl-vGgd----deelflehwqgd---vnylsdvysplrv--lrklrnlskpvvvqdilGvskaatlvaieiallsllrGpitksl

IVDIVKSIRSQRPRAVDSFCQYCSLYISLLYFIK
.| .|. .|.|  .|  .|  .|.||.       
vlravvflrlrrrlsvesvllylfvyrlvlffir

Phosphatase Y57G11C.6.AA Subfamily.R_Anemone_2.PD 187-432 21 4.4e-12 37.0 In-house 4-259 (262) Show / Hide
Range on Protein: 187-432
Range on HMM: 4-259/262
Sequence Identity: 21% (55 aa)

KEFEKLQSMKVD-VEKECKTWKANSKYNQSEDFPALDS-------NLLKVEKDYVNISRVEIPLGRNIYI-GQVPVKDTEETFWKAVFDKRIVSIdVIVG
.|.|.|.  .   |. .  . ..| . |.  .  | |.          ... ||.| . ..    .. ||  | |. .| | ||.|...    | |.. .
eeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavi-vmlt

DEP-------IEFFPKKaeDYKNYGQMWINNRKVEYVSDDVFRfSIEVLPHGCSNSIICNVTVISNWKVDSVPVKQaIAIKEAFGLNSYLLKAPADDNAM
|          ..|.|  . ..||.. .. ..   .|| | | |..|  ...... .     . .|.|| .    . .  .  ..  . .  .  ..   
qeeergkakvhryWPsk--gsrsygklvvelkeevelsdyvlr-sfkvkrteeeeerqvrqfhytsWpdegvpesg-aslldlvrqvekaqqesgagpiv

INSQHGAGRAGYFLALAVAVHTIDTKvAEPCIVDIVKSIRSQRPRAVDSFCQYCSLYISLLY
 | ||.| |.|. . .. |    |   . ..|| .|.||.  |    ||.|  ||       
vhcsaGvGrtGvfiavdillerikae-alvdvfqtvkqlreqrnlmvqtkdqyefiydvlle

Phosphatase Y57G11C.6.AA Subfamily.N_Nematode_1.PD 185-433 20 1.7e-09 28.3 In-house 2-263 (265) Show / Hide
Range on Protein: 185-433
Range on HMM: 2-263/265
Sequence Identity: 20% (54 aa)

VKKEFEKLQSMKVDVekECKTWKANSK--YNQSEDFPALDSNLLKV-----EKDYVNISRVEIPLGRNIYI-GQVPVKDTEETFWKAVFDKRIVSIDVIV
...||..|. ..     . |..|....   |. .| . || | .|.      .||.    | .|   . .|  | |...| . ||  |. ... .| .. 
lrdefralkkfndee--kvkafkeaqeadknrykdvgcldknrvklaeeplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlc

-----G-DEPIEFFPKKAEDYKNYGQM----WI-NNRKVEYVSDD---VFRFSIEVLPHGCSNSIICNVtVISNWKVDSVPVKQAIAIkeafglnSYLLK
     |     |.|| | .. ... .      . |. .|. ...|   .    .||   |...  . ...|    ||  .  |.         | .. ..
kliekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthy-qWtdWPdrGvPpadlaal-------ellea

APADDN-AMINSQHGAGRAGYFLALAVAVHTIDTKVAEPCIVDIVKSIRSQRPRAVDSFCQYCSLYISLLYF
 .  ..    | ||.|  .|..  .  .      . . ..||.||.||.. .  ||  ..  || .      
vrgskgPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvllny

Phosphatase Y57G11C.6.AA Subfamily.N23.PD 226-430 15 3.5e-09 27.0 In-house 127-346 (350) Show / Hide
Range on Protein: 226-430
Range on HMM: 127-346/350
Sequence Identity: 15% (34 aa)

LKVEKDYVNISRVE--IPLGRNIYIGQVPVKDTEETFWKAVFDKRIVSIDVIVGDEPI------EFFPKKAEDYKNYGQMWINNRKVEYvSDDVFRFSIE
. . ||.| . ..   |   .. . | |.. |   ||. |....   | ... ..        ...|.. .. ...|.. .  ....  |..  ...  .
pgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslkslrs-segwiervlh

VLPHGCSNS-IICNVtVISNWKVDSVPVKQAIAIKEAFGLNSYL-----LKA--PADDNAMINSQHGAGRAGYFLALAVAVHTIDTKVAEPCIVDIVKSI
  |    .|..  . .| .  ||      ..     ....      ..   ..   ...   | ||.| |  .  |.. ....   . |...|. .| ||
lqhndvstvrlvchl-htttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagngiiniprvvrrl

RSQRPRAVDSFCQYCSLY-ISL
   |    ..  || ..|    
rqqRkymvqkkvilkklyeavl

Phosphatase Y57G11C.6.AA Subfamily.R_Nematode_3.PD 189-424 14 5.8e-09 26.5 In-house 6-256 (267) Show / Hide
Range on Protein: 189-424
Range on HMM: 6-256/267
Sequence Identity: 14% (38 aa)

FEKLQSMKVDVEKECKtwkANSKYNQSE-------DFPALDSNLLKVEKDYVNISRVEIPLGRNIYIGQVPV--------KDTEETFWKAVFDKRIVSId
|||...... .... .   .... .. .       .  .|.    . . |... ..||.| | .. . | |         |.|| ||... ...  .. |
fekiaklakknatsls---kkvsedrrvevpllektrvvLkgygkrfkddfihAnvvecpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqv-

VIVGDEP----------IEFFPKKAEDYKNYGQMWINN-RKVEYVSDDVFRFSIEVlPHGCSNSIICNVTVISNWKVDSVPVKQAIAIKEAFGLNSYllk
 ..|             |..|.|..   . ... ..   . . .|.|| . ...|      . .  .. ... ||  ..| ..  |.. .  ....    
vmlcdfveedgeeeekcseYypekvdgelkfegvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfveks---

apaDDNAMINSQHGAGRAGYFLALAVAVHTIDTKVAEPCIVDIVKSIRSQRPRAVDSFCQYC
    ....   .| .|.. . |  ... .| ..  .  .....|..|.||..|. .  ..  
---ktpvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelela

Phosphatase Y57G11C.6.AA Subfamily.RC.PD 229-429 22 1e-08 25.6 In-house 72-282 (288) Show / Hide
Range on Protein: 229-429
Range on HMM: 72-282/288
Sequence Identity: 22% (46 aa)

EKDYVNISRVEIPLGRNIYI-GQVPVKDTEETFWKAVFDKRIVSIDVIV----GDEPI--EFFpkkAEDYKNYGQMWINNRKVEYVSDDVFRfSIEVLPH
.|.| | ..     . ||  | | |.| . ||. .|....  | ..     ||. .  |..    |  . ||.. .. .. .  || ..|.|.  .   .
gskyinasfidsykkpekyiaaqGplketvddfwrmiferkvkvivmltelkeGdrekcaeyw---eeGkrayGdvevdlkdtdkssdyilr-klelvnk

GCSNSIICNVTVISNWKVDSVPVKQAIAIKEAF--------GLNSYLLKAPADDNAMINSQHGAGRAGYFLALAVAVHTIDTKVAePCIVDIVKSIRSQR
|        ..| |. .| .    .|             .|   |       ..  . |..|.| |.||   . ...... ..|| .| .||  |. . |
krkdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeek-vdvfqvvkklrkar

PRAVDSFCQYCSLYIS
|  ||           
plmvsveeqyillydv

Phosphatase Y57G11C.6.AA Subfamily.N9.PD 185-433 19 2.1e-08 24.9 In-house 2-273 (275) Show / Hide
Range on Protein: 185-433
Range on HMM: 2-273/275
Sequence Identity: 19% (54 aa)

VKKEFEKLQSMKVDVEKECKTWKANSKYNQSEDFPALDSNLLKVE-------KDYVNISRVEIPLGRNIYIG-QVPVKDTEETFWKAVFDKRIVSIDVIV
..||........|  . ..   .||.. |. .|   .|.  .|..        ||.| . |.    .. .|. | |.| | . ||. |......| ..  
lskeyadirnepveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmtt

G---D---EPIEFFPKKAEDYKNYGQMWINNRKVEYVSDDVFR-FSIEVLPHGCSNSIIC-NVTVisnWKVDSVPVKQ--AIAI----KEAFGLNSYL--
          ...|.. |. ...|.. ..| .||  .| ..| . |.   .. | ...   ..    |    ||      . ..|. .| .         
rvvergrlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqfls---wPdyGvPssaaslldvlekvrekqalavkelg

---LKAPADDNAMINSQHGAGRAGYFLALAVAVHTIDtKVAEPCIVDIVKSIRSQRPRAVDSFCQYCSLYISLLYF
 . .   ..    | ||.| | .| ...  .. .|.   .|. || .|.||  ..    ||   |...| .     
deskghlsgPPivvhcsaGiGrtGtfitldiclarle-evgtvdvvetvkllrtqrafsiqtpeqyefcylavley

Phosphatase Y57G11C.6.AA Subfamily.N6.PD 245-435 21 4.6e-08 23.6 In-house 97-295 (295) Show / Hide
Range on Protein: 245-435
Range on HMM: 97-295/295
Sequence Identity: 21% (41 aa)

NIYI-GQVPVKDTEETFWKAVFDKR--IV-SI--DVIVGD-EPIEFFPKKAEDYKnYGQMWINNRKVEYVSDDVFR-FSIEVLPHGCSNSIICNVTvISN
. ||  | ..||| . ||. |...   ..  .  .|  |    . ..|.. .. . .|.. ... . .  .| ..| ||..   .  ..  | ..|   .
kryiatqgcLkdtvsdFWrmvwqensrvivmttkevergknkCarYWPdeetkke-tGvitvtsisEkstadYtlRefsvshkdkdkeareifqyh-fka

WKVDSVPVKQAIAIKEAFGLNSYLLKAPADDNAMINSQHGAGRAGYFLALAVAVHTIDTKVAEPCIvDI---VKSIRSQRPRAVDSFCQYCSLYISLLYF
|| .. . ..    .|.   .       ...   | ||.| |. . . ...| .. ..  | ||   .|..|||| . | .||  .|. . ..|.     
WPdhgvpkdpgvvlnfledvnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdi-disksikdvrsqrsglvqteaqykfvykavqfy

IK
  
ie

Phosphatase Y57G11C.6.AA Subfamily.N5_RR.PD 230-433 17 5.7e-08 23.3 In-house 52-263 (265) Show / Hide
Range on Protein: 230-433
Range on HMM: 52-263/265
Sequence Identity: 17% (36 aa)

KDYVNISRVEIPLG-RNIYI-GQVPVKDTEETFWKAVFDKRIVSIDV---IVGDE---PIEFFPKKAED--YKNYGQMWINNRKVeyVSDDVFRFSIEVL
.|.|   .  . .  ..|.  | |.  | . ||. .. ...  | .   .   .     ..||.. .    ..||.. |.....  |. ...    || .
ssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdaedyeiserygdveikveei--verndysvrklvl

PHGCSNSIICNVTVISNWKVDSVPVKQAIAIKEAFGLNSYLLKAPAD-DNAMINSQHGAGRAGYFLALAVAVHTIDTKVAePCIVDIVKSIRSQRPRAVD
  . .  .     ..|    .| .    ..     ..   .. |     ..    | ||.| |.|  .||. .. ... ||  .| .|   |..  ||  
kylerversvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiaisiavrqlreeiv-vdvlkivcnlrldrGGmvq

SFCQYCSLYISLLYF
..  |  .       
tseqyelihralcly

Phosphatase Y57G11C.6.AA Subfamily.N1.PD 195-312 19 2.3e-07 21.4 In-house 18-139 (268) Show / Hide
Range on Protein: 195-312
Range on HMM: 18-139/268
Sequence Identity: 19% (24 aa)

MKVDVEKEcKTWKANSKYNQSEDFPALDSNLLKVEKDYVNISRVEIPLGRNIYI-GQVPVKDTEETFWKAVFDK---RIVSIDVIVGDEPI---EFFPKK
... . |  .. ..  .|   . .     .| . ..||.| | ||..  .  ||  | |. .| . ||. |...    .. .. .|  . |...|.. |.
letreakl-penrglnryrdvspydhsrikleradvdyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywpqe

AEDYknygQMWINN--RKVEYVSDDVF
     .. ...   ||...| ..    
eeea----ellleetklkvkliseerk

Phosphatase Y57G11C.6.AA Subfamily.N_Choan_2.PD 232-434 15 2.6e-07 21.0 In-house 51-265 (266) Show / Hide
Range on Protein: 232-434
Range on HMM: 51-265/266
Sequence Identity: 15% (33 aa)

YVNISRVEIP-LGRNIYIG-QVPVKDTEETFWKAVFDKRIVSIDVIVG------DEPIEFFPKKAEDYKNYGQMWINNRKVEYVSDDVFRF-SIEVLPHG
|.|   |.     .. ||  . |.. | ..||. .....  .| .. |      ..   ..|.....  .. .. |. .... . .....  ...  .| 
YinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkladgkikvlalseekeegyiltrlrlekkg

CSNSIIcnVTVISNWKVDSVPVKQA--IAIKEAFGLNSYLLKAPA--DD--NAMINSQHGAGRAGYFLALAVAVHTIDTKVAEPCiVDIVKSIRSQRPRA
....        .|  ..|| ..   .  ..   .   . .     |.    ..    | ||.| ..|.  ||......    . . |.. .| .|.  |
etrrlv--HfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtliaiDiavrlLeetkkvdv-laiieelRkdRmal

VDSFCQYCSLYISLLYFI
.   ||  || ... .. 
vqhpeqyellykavveya

Phosphatase Y57G11C.6.AA Subfamily.N20.PD 187-428 25 2.9e-07 21.2 In-house 4-250 (257) Show / Hide
Range on Protein: 187-428
Range on HMM: 4-250/257
Sequence Identity: 25% (62 aa)

KEFEKLQSMKVDVEKECKTWKANSKYNQSEDFPALDSNLL--KVEKDYVNISRVEIPL-GRN-IYI-GQVPVKDTEETFWKAVFDKRIVSIDVIVGD---
.||  |.  ..  | ..    .| . |.  |    ||  .     |||.| | . |   | . .||  | |.  | . ||. |...    | .|  .   
qefmalelknlpgefnsgnqpsnreknryrdilpydstrvplgkskdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieg

---EPIEFFP---KKAEDYKNYGQMWINNRKVEYVSDDVFRFsiEVLPHGCSNSIicNVTVISNWKVDSVPVKQAIAIKEAfglnSYLLKAPADDNAMIN
   .   ..|   ||  . | .  .  | . ..|.   .|.        | | |.  .   ...|     |      |||  |.      ..    | ||
giikcyhywpislkkplelkhfrvflenyqilqyfiirmfqv--vekstgtshsv--kqlqftkwpdhgtpasadsfikyi----ryarkshltgpmvvh

SQHGAGRAGYFLALAVAVHTIdTKVAEPCIVDIVKSIRSQRPRAVDSFCQYCSLYI
.| ||.. | . .|  | .   |.|||  .| ||   |..  ||   |        
csagigrtgvflcvdvvfcai-vkncsfnimdivaqmreqrsgmvqtkeqyhfcyd

Sequence
Name Sequence Type Origin Length Description Download
Y57G11C.6.AA Protein None 482 None Fasta, JSON
Y57G11C.6.NA RNA None 1446 None Fasta, JSON
Y57G11C.6.AA.PD_184-435 Protein Phosphatase Domain None 252 None Fasta, JSON