• Phosphatome.Net

Gene ptp-2

ptp-2
Species: C.elegans
Alias: ptp-2
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: N6
Protein domain

Protein domains of ptp-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 ptp-2.AA SH2 8-98 33 2.4e-23 84.79 SMART 1-87 (87) Show / Hide 
Range on Protein: 8-98
Range on HMM: 1-87/87
Sequence Identity: 33% (31 aa)

QYNFYYRVNGEKAEELLKEY-GEDGDFLLRYSESNPQNFSISVRVAEDKILHIKVTKYESDMLSIFEDERTTPNQFGSITELAEFYMEFPEK
|  .. ....|.||.||| . ..|||||.|.|||||. ...|||.  .|. |... . .... .| |.   .. .| |. || ..|.  |  
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK-GKVKHYRIRRNDDGKYYIDET---WRRKFPSL-ELVNHYQHNPLG
SH2 ptp-2.AA SH2 132-217 33 4.9e-25 90.41 SMART 1-87 (87) Show / Hide 
Range on Protein: 132-217
Range on HMM: 1-87/87
Sequence Identity: 33% (30 aa)

YRWWHGNLPASSANKLLQT--EKNGTYLLRASQHIPGALVISAKTEGQVVHLTIYQDPSTGRFNIDG-DRTKFQSAWLLIDSYSKNPIV
. | |||.. . | .||..   ..|..|.| |.. ||..|.| ...|.| |  | .... |.. ||. .|.||.|   |.. |..||..
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDD-GKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 ptp-2.AA SH2 11-92 29 2.2e-14 44.07 Pfam 2-81 (81) Show / Hide 
Range on Protein: 11-92
Range on HMM: 2-81/81
Sequence Identity: 29% (25 aa)

FYYRVNGEKAEELLKE-YGEDGDFLLRYSESNPQNFSISVRVAE--DKILHIKVTKYESDMLSIFEDERTTPNQFGSITELAEFY
..  .....||.||..  ..||.||.| |||.|  ...|||     |.. |... . .   . |.....     |.|. || |.|
YHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHK-----FCSLQELVEHY
Phosphatase ptp-2.AA Subfamily.N6.PD 259-582 50 5.1e-116 378.4 In-house 9-295 (295) Show / Hide 
Range on Protein: 259-582
Range on HMM: 9-295/295
Sequence Identity: 50% (150 aa)

MEKTGISEEFDRLSQEAlpAEQYLSKREGRRPVNAEKNRYKNIVPFDHTRVILTDR-PNTPGSDYINASYVRFENSQRTKNVTFACE---KSFIATQGCL
.  |..|||..|....  .|...|..||... |.||||||||.|||||||||.|. |..||||||||.|.|......... ....|   |..|||||||.
sqtlgfweefeelqkqe--seklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcL

ETTISDFWSMVWQENSRVIVMPTMENER-KEKCARYWPAEVNKPEvHGDISLTCTIERKVQravsdevkaeleqektnriakglvpeaelngdgiSYILR
.|.||||.|||||||||||| |.|.|| |.|||||||.| .| | .|.|..|.. |.. ..|.||.....   | |..|||.|... .|||||.| .|..
kdtvsdFWrmvwqensrvivmttkevergknkCarYWPdeetkke-tGvitvtsisEksta----------------------------------dYtlR

TLVMK---KGKDTREIRQLQYLTWPDHGCPLHPYAVLNFLEDVDREYDYFnaqpiaasLPQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVGLLCPMDVY
||||||||.......          .||||||||||||||||..|.|..|..... || ...|..|..|.||..||||||||.||.|.|||..||..   
efsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfledvnkkqeel--------ekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidis

KMVKYVRTYRSGLVQTEQQYQFLYKALAFYLK
                                
ksikdvrsqrsglvqteaqykfvykavqfyie
SH2 ptp-2.AA SH2 134-211 27 2.5e-17 52.7 Pfam 1-81 (81) Show / Hide 
Range on Protein: 134-211
Range on HMM: 1-81/81
Sequence Identity: 27% (23 aa)

WWHGNLPASSANKLLQT--EKNGTYLLRASQHIPGALVISAKTEG---QVVHLTIYQDPSTGRFNIDGDRTKFQSAWLLIDSY
| ||... . | .||.    ..||.|.| |.  ||  ..| ...|   .| |  | ...  | . .....  |.| . |.. |
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHK--FCSLQELVEHY
Phosphatase ptp-2.AA PTPc 263-582 31 3e-125 423.3 SMART 1-308 (308) Show / Hide 
Range on Protein: 263-582
Range on HMM: 1-308/308
Sequence Identity: 31% (114 aa)

GISEEFDRLSQEALPAEQY-----LSKREGRRPVNA--EKNRYK-NIVPFDHTRVILTDRPNT----PGSDYINASYVRFENSQRTKNVTFACEKSFIAT
|..|||.|| ..  . ...      |......| |.  .||||| .|...|||||.|...|      .|||||||.|....           ..|..|.|
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY----------WRPKRYICT

QGCLETTISDFWSMVWQENSRVIVMPTMENER---------KEKCARYWPAEVNKPEVHGDISLTCTIERKVQRAVSDEVKAELEQEKTNRIAKGLVPEA
||.|. ||.||| ||||.....||| ....|.         .|||..||| |   |...|.|..||. | |..                           
QGPLPHTIEDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE---PMTYGHITVTCKSEEKCP---------------------------

ELNGDGISYILRTLVMKKGK----------DTREIRQLQYLTWPDHGCPLHPYAVLNFLEDVDREYDYF----------NAQPIAASLPQGPIVVHCSAG
       .|..||.  ....          .||......| .|||||.| .| ..|.|...|.  .  .          |.  .... |.||||||||||
------DDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNS-KYHHTCPTGPIVVHCSAG

IGRTGTVLVLDALLNQVKKVGLLCPMDVYKMVKYVRTYRSGLVQTEQQYQFLYKALAFYLK
.||||| ...|....|...       |....|| .|..| |.||||.||.|.|.....|.|
CGRTGTFCAIDIMCQQIEN------VDIFQIVKMMRNQRPGMVQTEEQYIFCYRCILEYIK
Phosphatase ptp-2.AA Y_phosphatase 292-579 33 3.4e-97 334.01 Pfam 1-243 (243) Show / Hide 
Range on Protein: 292-579
Range on HMM: 1-243/243
Sequence Identity: 33% (100 aa)

NAEKNRYKNIVPFDHTRVILTDRPNTPGSDYINASYVRFENSQRTKNVTFACEKSFIATQGCLETTISDFWSMVWQENSRVIVMPTMENERKE--K-CAR
| ||||||.|...|||||.|.. |. ..||||||.|...          .  .| .|.||| .. || ||| ||||.....||| . . |..   | |..
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDG---------PYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQ

YWPA-EVNKPEVHGDISLTCTIERKVQRAVSDEVKAELEQEKTNRIAKGLVPEAELNGDGISYILRTLVMKKGKD----TREIRQLQYLTWPDHGCPLH-
|||  ... |...||.. ||. | .                                     |..||. ... .|    ||......|..|||||.| . 
YWPDNKEGQPMTYGDFQVTCVSEEH----------------------------------CPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQ

PYAVLNFLEDVDREYDYFNAQPIAASLPQG--PIVVHCSAGIGRTGTVLVLDALLNQVKKVGLLCPMDVYKMVKYVRTYRSGLVQTEQQYQFLYKALAF
| ..|.|.. |   .          .   |  |||||||||.|||||  ..|... |... | .   |....|| .|. | |.||||.||.|.|.... 
PKSMLDFIRQVRKWQP---------NPDHGCPPIVVHCSAGCGRTGTFCAIDIMCQQMEHEGTV---DIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE
Phosphatase ptp-2.AA Subfamily.RG.PD 265-579 31 2.4e-63 205.4 In-house 3-261 (264) Show / Hide 
Range on Protein: 265-579
Range on HMM: 3-261/264
Sequence Identity: 31% (100 aa)

SEEFDRLSQEalpAEQYLSKREGRRPVNAEKNRYKNIVPFDHTRVILTDRPNTPGSDYINASYVRfensqrtknvTFACEKSFIATQGCLETTISDFWSM
.|.|. ...    ......    ... | ||||. |||.....|| |.. |.. |.|||||||..           .  .| .|.||| |..||||| |.
eeqfeeiqkl---kpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyid----------GyrrskeyivtqgplketiedFWrm

VWQENSRVIVMPTM-ENERKEKCARYWPAEvNKPEVHGDISLTCTIERKVqravsdevkaeleqektnriakglvpeaelngdgISYILRTLVMKKGKD-
|..|...||| |  ... ......|||.. ..|.  .....| . . |.                                   .|..|..|.|. ||  
iWehnaqiivmltdldekgrrdedvyWPkk-deplelealkvtllskekl----------------------------------skytvrdfvlkntkdd

---TREIRQLQYLTWPDHGCPLHPYAVLNFLEDVdreydyfnaqPIAASLPQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVGLlcpMDVYKMVKYVRTY
  .|..||..| .|||.| | . . ||.| .              | .  .||||||.||| ||.|| ..||.||.|..|..||...| .|. | |||.|
kekervvrqyhytkWPdmgsPestlfvlifvkke----------eaankeeaGPivvhdsaGvgragtyialdtllqqlekeea---vnvyqvlklirak

RSGLVQTEQQYQFLYKALAF
| ||.|.|.|| .       
RpglvtteEqyvfiydalle
Phosphatase ptp-2.AA Subfamily.N5_RR.PD 283-582 30 2e-60 195.7 In-house 14-265 (265) Show / Hide 
Range on Protein: 283-582
Range on HMM: 14-265/265
Sequence Identity: 30% (92 aa)

SKREGRRPVNAEKNRYKNIVPFDHTRVIL-TDRPNTPGSDYINASYVRFENSQrtknvtfacEKSFIATQGCLETTISDFWSMVWQENSRVIVMPTMENE
|..| . . ...|||||.|.| ...||.| .. .. . |.|||| |..  . .         .| ..|||| | .||.||| |..||...|||| |  .|
sqeelevfgsqtknryktilPnensrvllesessededssyinanyikGydee---------skayvatqGPlpntiadfWrmiyqeevqvivmltklke

RKE-KCARYWPAEVNK--PEVHGDISltctierkvqravsdevkaeleqektnriakglVPEAELNGdGISYILRTLVMKKGKD-TREIRQLQYLTWPDH
... |||.|.| . .    | .||..                                 .   | .     | .|.||.|... .|..    |  |||| 
anrqkcavyfPdaedyeiserygdve---------------------------------ikveeive-rndysvrklvlkylerversvkhywytdWPdh

GCPLHPYAVLNFLEDVdreydyfNAQPIAASLPQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVGLlcpMDVYKMVKYVRTYRSGLVQTEQQYQFLYKAL
 | .. ..|.....|       . .  ... . .|.||||||||||||  .  .  ..|... .    .|||.|  .|  | |.|||..||.....||. 
ksPddintlldlvlev-------eesreeenaklaPvvvhcsaGiGrtGcfiaisiavrqlreeiv---vdvlkivcnlrldrGGmvqtseqyelihral

AFYLK
|||  
clylk
Phosphatase ptp-2.AA Subfamily.R_Ecdysozoa.PD 264-580 35 5.1e-60 194.3 In-house 2-267 (269) Show / Hide 
Range on Protein: 264-580
Range on HMM: 2-267/269
Sequence Identity: 35% (103 aa)

ISEEFDRLSQEAlpaEQYLSKREGRRPVNAEKNRYKNIVPFDHTRVILTDRPNTPGSDYINASYVRfensqrtknvTFACEKSFIATQGCLETTISDFWS
. ||...| ...   |  .| . . .  || ||||..|..||.|||.|.  . .  |||||||...          ..  .|.||| |. .|.|| ||| 
leeeyekLearl---eiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfik----------gykekkkfiaaqdPveatigDfWr

MVWQENSRVIVMPTMENERKEKCARYWPAEvnKPEVHGDISLTCTIERKVQRAVSDEVKAELEQEKTNriakglvpeaelngdgisyilrtlvmkkgKDT
|... .. .||| . ..| ..|||.||| |  .   .|||  ..  |.| .  .  |..    .|...|.|.. | .| .|. |   | .. ..|...| 
miaeqevtlivmlsnlteknrkcakyWpie--devqygdilvklvseekhsdyiireldvskkkeesv-----------------------------eds

REIRQLQYLTWP-DHGCPLHPYAVLNFLEDVDREYDyFNAqpiaASLPQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVGllcPMDVYKMVKYVRTYRSG
|   |  .|      |  ..||||||||| ||.|... || ||.|.|.      .|....|| .|  |. |||  .||.|||.||| |            
rkvvqysytgWksDskvPevargllklieqvrelyk-lnk----lsgsrsPivvhCsaGvgrsgifvaldlllqqlkaed---kvdifetvkkLrsqrnl

LVQTEQQYQFLYKALAFY
                  
lvqsleqyvflyralady
Phosphatase ptp-2.AA Subfamily.N_Fungi_PTP1.PD 294-581 29 8.8e-45 144.5 In-house 47-342 (343) Show / Hide 
Range on Protein: 294-581
Range on HMM: 47-342/343
Sequence Identity: 29% (91 aa)

EKNRYKNIVPFDHTRVILTDRPN--------TPGSDYINASYVRFENSQRTKNVTFacekSFIATQGCLETTISDFWSMVWQENSRVIVMPTMENER-KE
|||||||.|..|.||.|   ..        . ..|||||.|.. .      |  |     .||||. |  |. ||. .. . ..||.. | . |   |||
aknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdf----kYiatqaPlpstvddfykvillnkvkvilsltsdvelnle

KCARYWPAEvNKPEVHgdISLTCTIERKVQRAVSDEVKAELEQEKTNRIAKglVPEAELNGDGISYILRTLVMKkgkdTREIRQLQYLTWPDHGCPLHPY
 |||.   .  ...  . |. . |  .    |    |....| ..   |  . . .|| ..    ...| .      |. |||.  |.| .  |.|  .|
kcyrYWqeg-syddit--vklaskwenimgindsslysadvkkeasdndnk--sddndlnnnndltpvtaavse----pyevyqlqvknWkDlslllnPe

AVLNFLEDVDREYDYFNAQPIAASLPQGPIVVHCSAGIGRTGTVLVLDALLNQV----------KKVGLLCP-MD-VYKMVKYVRTYRSGLVQTEQQYQF
. ||  .   |  .|.    .  . ||.||||||.|||||.. || ||...          .|.       | .  .|. .|  |  .||. .|. |.|.
silqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfif

LYKALAFYL
|| ||    
iYeallfyf
Phosphatase ptp-2.AA Subfamily.N_Nematode_1.PD 291-580 31 3e-43 139.4 In-house 25-263 (265) Show / Hide 
Range on Protein: 291-580
Range on HMM: 25-263/265
Sequence Identity: 31% (90 aa)

VNAEKNRYKNIVPFDHTRVILTDRPNTpgSDYINASYVrfensqrtkNvTFACEKSFIATQGCLETTISDFWSMVWQENSRVIVMPT-MENERKEKCARY
.|.|||||..   |..||.|.. | .  |||| | ||           | .  | || .|. |. ||.||| || ||.   |||   . .. | ||| |.
qeadknrykdvgcldknrvklaeeplp--sdyihanyv---------g-tptnpkrficaqaPldktiadfwymvlqekveaivmlckliekgkkkcaey

WPAEVNKPEVHGDISLTCTIERKVQRAVSDEvkaeleqeKTNRiakglVPEAELNgdgisyilrtlVMKKGKDTREIRQLQYLTWPDHGCPLHPYAVLnf
||. ..  .  . . ..|.| ...    .|        . .      . ...|.           ||..||.....|.  |||.| |    |.|      
fpakegeklefkekgqkitvenslgvkklee--------deev-----ikvtvle-----------vegaGektrkvthyqWtdWPdrGvPpadlaal--

ledvdreydyfnaQP-IAASLPQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVGLLcpMDVYKMVKYVRTYRSGLVQTEQQYQFLYKALAFY
         .   |.   .||||||||||||||||..... .|... ..  .|. |.|| .|  |.  .||..|| |... |  |       
-------------elleavrgskgPivvhCsaGiGrtGtivaieyildkllegkqi--edmeklvkkireqrnysiqtdaqylfvhrvllny
Phosphatase ptp-2.AA PTPc_motif 465-579 33 2.2e-40 141.41 SMART 1-92 (92) Show / Hide 
Range on Protein: 465-579
Range on HMM: 1-92/92
Sequence Identity: 33% (40 aa)

EIRQLQYLTWPDH-----GCPLHPYAVLNFLEDVDREYDYFNAQPIAASLPQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVGLLCPMDVYKMVKYVRTY
......|..||||     |.|    ..| |.. |                   |||||||||.|||||. ..| ...|         .|....||..|..
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-----------------PIVVHCSAGCGRTGTFCAIDMMMQQ---------VDIFQTVKEMRKQ

RSGLVQTEQQYQFLYKALAF
| |.||||.||.|.|.....
RPGMVQTEEQYIFCYRCILE
Phosphatase ptp-2.AA Subfamily.R_Anemone_2.PD 264-434 38 2.2e-38 123.7 In-house 2-158 (262) Show / Hide 
Range on Protein: 264-434
Range on HMM: 2-158/262
Sequence Identity: 38% (65 aa)

ISEEFDRLSQEAlpaEQYLSKREGRRPVNAEKNRYKNIVPFDHTRVILTDRPNTPGSDYINASYVRFENSQrtknvtfaceKSFIATQGCLETTISDFWS
.|||..|||..    |. .. ..  .|||. |||| ||...|.||| |... ...|||||||.|.   ...          |..||||. |  ||.||| 
lseeyerlsrse---etsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrk----------kayiatqaPlpetiedfWr

MVWQENSRVIVMPTMENER-KEKCARYWPAEvnKPEVHGDISLTCTIERKVQRAVSDEVKAELEQEKTNRIA
|||. ||.|||| | |.|| | |..|||| .  ... .|..  . . | ...  |  ..| . ..|. .|. 
mvWeqnsavivmltqeeergkakvhryWPsk--gsrsygklvvelkeevelsdyvlrsfkvkrteeeeerqv
Phosphatase ptp-2.AA Subfamily.N12.PD 266-415 36 1.9e-36 117.0 In-house 4-146 (270) Show / Hide 
Range on Protein: 266-415
Range on HMM: 4-146/270
Sequence Identity: 36% (55 aa)

EEFDRLS--QEALPAEQYLSKREGRRPVNAEKNRYKNIVPFDHTRVILTDRPNTPGSDYINASYVRFENSQrtknvtfaceKSFIATQGCLETTISDFWS
.|| .|   .|.. ||.  |. .|....| .|||||.|.|.|..||.|.   ...|||||||....  ...          ...||.|| | .|..||| 
kefqklkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegk----------leyiaaqgPLpktlddfWr

MVWQENSRVIVMPTMENE-RKEKCARYWPAEVNKPEVHGDISLTCTIERKVQR
|.|. | ...||  .| |  | ||.|||| |....  .|....|.. |..|. 
miweknveivvmaCrevelgkkkCeryWpeegeeelefgefevtleeekavdd
Phosphatase ptp-2.AA Subfamily.R_Anemone_1.PD 266-414 39 3.4e-36 116.6 In-house 4-135 (258) Show / Hide 
Range on Protein: 266-414
Range on HMM: 4-135/258
Sequence Identity: 39% (58 aa)

EEFDRLSqealpAEQYLSKREGRRPVNAEKNRYKNIVPFDHTRVILTDRPNTPGSDYINASYVRFENsqrtknvtfaCEKSFIATQGCLETTISDFWSMV
.||.||.      ..  .|  .|.. | .||||..||..||.||.|..  | . ||||||||.|  .            ..|||||..||.|..||| ||
aefqrlk-----eikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasd----------ktrafiatqapleetvedFWrmv

WQENSRVIVMPTMENE-RKEKCARYWPAevnKPEVHGDISLTCTIERKVQ
|||.. |||| |  .| .|.|| .|||    ..| .|..... . . .  
wqekigviVmLtnliegekkkchqYwPd---stekygelrvslrkkevfa
Phosphatase ptp-2.AA Subfamily.N3.PD 282-432 37 7.8e-35 111.7 In-house 16-156 (261) Show / Hide 
Range on Protein: 282-432
Range on HMM: 16-156/261
Sequence Identity: 37% (57 aa)

LSKREGRRPVNAEKNRYKNIVPFDHTRVILTDRPNtpgsDYINASYVRFENSQRTKNvtfaceKSFIATQGCLETTISDFWSMVWQENSRVIVMPTMENE
|.  . |.| |..||||..|.|.|.|||.|.. ..    |||||.|| .| .  .        . .||||| |..| .||| |||...|..||||   ||
laisaarkpenlaknryrdilpydatrvklkeset----dyinanyvnmeipstglv------nryiatqGplaktakdfWqmvweqkstlivmlttlve

R-KEKCARYWPAEVNKPEvHGDISLTCTIERKVQRAVSDEVKAELEQEKTNR
 . || .||| . .. | .|..|..|. |.. .  |  |.  . ...| .| 
rGrvkChqyWPetedele-fgefsvrcekedetksyvlrelvlkdketkeer
Phosphatase ptp-2.AA Subfamily.RB.PD 280-429 40 8.6e-35 111.7 In-house 14-153 (261) Show / Hide 
Range on Protein: 280-429
Range on HMM: 14-153/261
Sequence Identity: 40% (61 aa)

QYLSKREGRRPVNAEKNRYKNIVPFDHTRVILTDRPNTPGSDYINASYVRFENSQRtknvtfacekSFIATQGCLETTISDFWSMVWQENSRVIVMPTME
.  .... ...|| .|||..||.|.||.|| |..  .....|||||.|.   ||.|           .||||| |..|. ||| |||...|..||| |  
kdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspr----------eyiatqGPlpetvddfWrmvwekkssiivmltql

NE-RKEKCARYWPAEvNKPEVHGDISLTCTIERKVQRAVSDEVKAELEQEK
 |  |||| .||||. ..| ..|||..| . |....  |  |.| | ..||
vEkgkekceeYWPad-eepvlyGdikvtllaekeldewvirefkiekgkek
Phosphatase ptp-2.AA Subfamily.N12.PD 449-579 36 1.5e-34 110.7 In-house 147-267 (270) Show / Hide 
Range on Protein: 449-579
Range on HMM: 147-267/270
Sequence Identity: 36% (46 aa)

SYILRTLVMKKGKDTREIRQLQYLTWPDHGCPLHPYAVLNFLEDVDREYDyfnaqpiaasLPQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVGLLCPMD
...||| ... |..|...|..|  |||||.|  .  .|...|.| .  .            . |.|||||||.|||||....|   ...|..   .||..
dflirtLkveaqkesrkvyqfhytaWPDhgvPssaksllelielvrelqe----------sedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeld

VYKMVKYVRTYRSGLVQTEQQYQFLYKALAF
.|  .|. |. ||||..||...|||.|    
vfdlvlelrkqraalvqtkeqyelvykavae
Phosphatase ptp-2.AA Subfamily.N9.PD 263-417 37 1.9e-34 110.7 In-house 1-141 (275) Show / Hide 
Range on Protein: 263-417
Range on HMM: 1-141/275
Sequence Identity: 37% (57 aa)

GISEEFDRLSQEALPAEQYLSkregRRPVNAEKNRYKNIVPFDHTRVILTDRPNTPGSDYINASYVrfeNSQRTKnvtfaceKSFIATQGCLETTISDFW
|.|.|.  . .|.   . . |    . ..| |||||.... .|.||| |. ..... ||||||..|   .  . |       |.|||||| |.|.|||| 
GlskeyadirnepveGtflas----klranleknrytdvlcydetrvklakldedeasdyinanfv---dGykqk-------kafiatqGplkktvsdfw

SMVWQENSRVIVMPTMENE-RKEKCARYWPAEVNKPEVHGDISLTcTIERKVQRAV
|||... .|||| |   | .. ||..||| | .. . .||.|.. ..| .|...  
rmvweqevlvivmttrvvergrlkcgqywpleeessaefgdlsvs-nveveveedy
Phosphatase ptp-2.AA Subfamily.R_Sponge_2.PD 277-418 37 7.9e-34 108.7 In-house 10-141 (262) Show / Hide 
Range on Protein: 277-418
Range on HMM: 10-141/262
Sequence Identity: 37% (53 aa)

PAEQYLSKREGRRPVNAEKNRYKNIVPFDHTRVILTDrPNTPGSDYINASYVRFENSQrtknvtfaceKSFIATQGCLETTISDFWSMVWQENSRVIVMP
. |.  |  ... . |  |||.|.|.|.|..|| |.  .....|||||||.|   ...          |..||||| |..|..||||||  ... ||| |
eketefslsiaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgykrr----------kayiatqgPlketveDfWRmvweykvstivml

T-MENERKEKCARYWPAEVNKPEVHGDISLTCTIERKVQRAVS
 .|.. |||||.||| .|..    |..  | . |.|..  .  
tnleengkekcakYWPekvdeeveygkfkvtlkeeekladyii
Phosphatase ptp-2.AA Subfamily.RA.PD 264-408 38 2.9e-33 106.7 In-house 2-132 (266) Show / Hide 
Range on Protein: 264-408
Range on HMM: 2-132/266
Sequence Identity: 38% (56 aa)

ISEEFDRLSQEALPAEQYlskREGRRPVNAEKNRYKNIVPFDHTRVILTDRPNTPGSDYINASYVrfeNSQRTKNvtfacekSFIATQGCLETTISDFWS
. ||| .|..  .  |.    | . .. | .|||. .|.|.|..||||. .  .. |||||||..   .  | |.       .|||.|| .| |. ||| 
leeefkkltsvkiqkekl---rtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfi---dGyrekd-------kfiaaqGpkeetvedfwr

MVWQENSRVIVMPTMENERK-EKCARYWPAEVNKpeVHGDISLTCT
|.|. .|  ||| |  .||| ||||.||| |      .|.| ..  
miweqksativmltelkerkeekcaqywpdeGlv--tyGeirvevk
Phosphatase ptp-2.AA Subfamily.RB.PD 449-578 39 3.4e-33 106.5 In-house 139-257 (261) Show / Hide 
Range on Protein: 449-578
Range on HMM: 139-257/261
Sequence Identity: 39% (49 aa)

SYILRTLVMKKGKDTREIRQLQYLTWPDHGCPLHPYAVLNFLEDVDREydyfnaqpIAASLPQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVGllcPMD
....|.. ..|||..|..||.....||||| | .. ..|.|.. |...        | ..  ..|||||||||.||||| . || ||......||. .| 
ewvirefkiekgkekrkvrqyhftsWpdhgvPektktlldfvrtvrea--------iekkaskkPivvHCsaGvGRtGtfialdrllqaieend---yvd

VYKMVKYVRTYRSGLVQTEQQYQFLYKALA
 .|. |  |||||.|| |....|.      
vfgvvaelReeRnllvqtekqyifihecll
Phosphatase ptp-2.AA Subfamily.R_Anemone_1.PD 449-581 39 1.1e-32 105.0 In-house 136-257 (258) Show / Hide 
Range on Protein: 449-581
Range on HMM: 136-257/258
Sequence Identity: 39% (53 aa)

SYILRTLVMKKGKD--TREIRQLQYLTWPDHGCPLHPYAVLNFLEDVDREydyfnaqpiaASLPQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVGLlcp
||.||||..| |   .||..|.....|||.| | .  |||.....| ..              . |.|||||||.||||. ||.||.|.|.||      .
dyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqks----------slagarpvvvhCsaGvgRtGaflvidamleqakkekv---

MDVYKMVKYVRTYRSGLVQTEQQYQFLYKALAFYL
|....|| .|. |  .|||..|| |...|.  .| 
vDifnyvkairedrphmvqtkeqyvfihlavleal
Phosphatase ptp-2.AA Subfamily.R_Nematode_2.PD 291-581 25 9.6e-32 101.6 In-house 28-260 (261) Show / Hide 
Range on Protein: 291-581
Range on HMM: 28-260/261
Sequence Identity: 25% (77 aa)

VNAEKNRYKNIVPFDHTRVILTDrpNTPGSDyINASYVRFensqrtknvtFACEKSFIATQGCLETTISDFWSMVWQENSRVIVMPTMENE-RKEKCARY
....|.||...   ..|.|      .   .. | | .|               .| |||||| || | .||| || ||.   ||| .   |  ||||..|
lpkdkhRypdvPCkpetaveviv--dgkrvp-ihanwvpt----------agnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeY

WPAEvnkpevhgdisltctierkvqR------AvsdevKAELEQEKTNRIAKGLvpeaelngdgISYilRTLV--MKKG-KDTREIRQLQYLTWPDHGCP
.| |                                  . .... ....|.|            |.|||    ..|  .|| .. .||  |||.| |   
fple---------------------tsqkldlg-----rfsiktvsaekilkde----------iek--rtlkvedstgkfatrtvthyqyeeWpdrgvP

LHPyavlnfledvdreYDYFNAQPIAaSLPQGPIVVHCSAGIGRTGTVLVLDALLNQVKKvglLCPMDVYKMVKYVRTYRSGLVQTEQQYQFLYKALAFY
              . |.   ..    . |||||||||||||....  .| ..|..      . . ...| .| .|.  .|||.|. .|  .. ..|   
ksh-------------aelfeLlelv-kksekPivvhCsaGiGRtmafigteylarevea---dptieltealkelrehRwkgiqtesqlywltlgalyr

L
 
l
Phosphatase ptp-2.AA Subfamily.R_Anemone_2.PD 449-581 36 5.4e-31 99.5 In-house 139-261 (262) Show / Hide 
Range on Protein: 449-581
Range on HMM: 139-261/262
Sequence Identity: 36% (49 aa)

SYILRTLVMKK--GKDTREIRQLQYLTWPDHGCPLHPYAVLNFLEDVDReydyFNAQPiaaslPQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVGLlcp
.|.||.. .|.   ...|..|| .| .|||.| | ..  .|... .|..     ....      .||||||||||.||||. ...|.||...|. .|   
dyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvek----aqqes-----gagpivvhcsaGvGrtGvfiavdillerikaeal---

MDVYKMVKYVRTYRSGLVQTEQQYQFLYKALAFYL
.||...|| .|. |. .|||..||.|.|..|  .|
vdvfqtvkqlreqrnlmvqtkdqyefiydvlleal
Phosphatase ptp-2.AA Subfamily.N13.PD 282-406 36 1.3e-30 98.1 In-house 16-129 (259) Show / Hide 
Range on Protein: 282-406
Range on HMM: 16-129/259
Sequence Identity: 36% (46 aa)

LSKREGRRPVNAEKNRYKNIVPFDHTRVILTDRPNtpgsdYINASYVRFENsqrTKNvTFacekSFIATQGCLETTISDFWSMVWQENSRVIVMPTMENE
.. ..|..  | .||||.|..|.|.|||.| |  .     |||||... .     .. ..    ..||.|| | .|..||| |||. ...||.| |.| |
dtcevgkkkenkdknryrnvlPydetrvklgdegg-----yinaslikvpv---ged-ey----eyiacqGPlPetvkdfwqmvweqkaeviamvtleke

R-KEKCARYWPAEVNKPEVHGD-ISLT
. | || |||| . ||. .  . . ..
kgkvkchrywPerknkklkvsnrleve
Phosphatase ptp-2.AA Subfamily.N23.PD 304-430 33 2.7e-30 97.0 In-house 114-233 (350) Show / Hide 
Range on Protein: 304-430
Range on HMM: 114-233/350
Sequence Identity: 33% (43 aa)

FDHTRVILTDRPN-TPGSDYINASYVrfensqrtKNVTFACEkSFIATQGCLETTISDFWSMVWQENSRVIVMPTMENER-KEKCARYWPAEVNKPEVHG
|..|| |   ..    .|||||.|.        |..|  .  .|||||| ...|..|||.|||.. |.|||| | |.|. | ||..|||........||.
hdpnrvklqqstqpgqqddyinatyl--------keltpmsP-pfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfg

DISLTCTIERKVQRAVSDEVKAELEQEKT
....  .|. .  .   .. . .. .|  
dlrvslkslrssegwiervlhlqhndvst
Phosphatase ptp-2.AA Subfamily.N_Choan_1.PD 449-580 36 3.2e-30 96.8 In-house 139-260 (262) Show / Hide 
Range on Protein: 449-580
Range on HMM: 139-260/262
Sequence Identity: 36% (48 aa)

SYILRTLVM-KKGKDTREIRQLQYLTWPDHGCPLHPYAVLNFLEDVDREYDYFNAqpiaaslpqGPIVVHCSAGIGRTGTVLVLDALLNQVKKVglLCPM
.|| |.. . ... .|||..||.|..||||| |  . ..|.| ..| .  .  .           |.|.|||||.||||| . || |...|..   . ..
tyierkfkleresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktk---------aplvihCsaGvGrtGtyialDrlvkaveek--aeal

DVYKMVKYVRTYRSGLVQTEQQYQFLYKALAFY
||  .|. .|  |  .|||  ||.|.|||.  .
dvkavvaelrkernlmvqtlvqyefvykavlda
Phosphatase ptp-2.AA Subfamily.N_Choan_1.PD 287-434 35 5.5e-30 96.0 In-house 21-158 (262) Show / Hide 
Range on Protein: 287-434
Range on HMM: 21-158/262
Sequence Identity: 35% (52 aa)

GRRPVNAEKNRYKNIVPFDHTRVILTDRPNTPGSDYINASYVRfensqrtknvTFACEKSFIATQGCLETTISDFWSMVWQENSRVIVMPTMENER-KEK
... | .||||.||| .|.||| .|.  ..  .|||||..|           ..  || .||||| . ... .|| |||... ..||| | | |  | ||
skadenvlknrysnivayDatrvkvtpneenkntDyinanfvp----------gykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvtreieagklk

CARYWPaEVNKPEVHGDISLTCTIERKVQRAVSDEVKAELEQEKTNRIA
 |||| . |.    ||. .. . |.. .. .. ..| | |. .| ... 
ChryWP-denselklgdvtvkslseeekktyierkfkleresgetreve
Phosphatase ptp-2.AA Subfamily.RA.PD 457-580 41 5.6e-30 95.9 In-house 153-264 (266) Show / Hide 
Range on Protein: 457-580
Range on HMM: 153-264/266
Sequence Identity: 41% (51 aa)

MKKGKDTREIRQLQYLTWPDHGCPLHPYAVLNFLEDVDREydyfnaQPIAAslpQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVGLLcpmDVYKMVKYV
... |..| .||. . .||. | | ..  .|..|. | .       |.  |   . |||||||||.||||| .||||.|..||  ..|   ||...|| .
atrekksrlvrqfhftswpevGvpaegkGmlkllkkvkkl------qqqsa---nhpivvhcsaGvGrtGtfivldavlervkaerkl---dvfeavkrl

RTYRSGLVQTEQQYQFLYKALAFY
|. |. .|||..||.|.||.|  |
rlqrpqmvqtleqyefiykvlley
Phosphatase ptp-2.AA Subfamily.R_Nematode_3.PD 291-573 23 1.6e-29 94.5 In-house 22-258 (267) Show / Hide 
Range on Protein: 291-573
Range on HMM: 22-258/267
Sequence Identity: 23% (62 aa)

VNAEKNRYKNIVPFDHTRVILTDRPNTPGSDYINASYVRFENSQR---TKNVTfacEK----SfiatqgcLETTISDFWSMVWQENSRVIVMPTMENE--
. ...|....  . .|||.| .  .   .|.|.|..| ..|. .   |.      .|             ..||  || |. ||.. ..||    .|   
kkvsedrrvevpllektrvvLkgygkrfkddfihAnvvecpnglklIltqsPq---kkdkekk-------kkstieKfwwmieqekveqvvmlcdfveed

--RKEKCARYWPAEVNKPEVHGDISLTCTIERKVQRAVSDEVKAELEQEktnriakglvpeaelngdgisyilrtlvmkkGKDTREIRQLQYLTWPDHGC
  .|||..|.| .|..    ...|..||   |   .  .. . ... ||..  .. |.|  |.... | .|. .|. .. |   .             . 
geeeekcseYypekvdgelkfegvsvkctdikkelsedvekrtlvvtfe-------------------------------kkkeftvthllykgWkelna

PLHPYAVLNFLEDVDReYdyfnaqpiaaslpQGPIVVHCSAGIGRTGTVLVLDALLNQVKKV-GllcPMDVYKMVKYVRTYRSGLVQTEQQYQFL
|.|||||.||.|..|  ..   . . |  |    .|. ...|..|  | | .|||... |.                                  
peepkealelikfvek-s-------------ktpvvVHCsdGisRsatlaaielgyqliikskg---kldllslikelrkqRagaiqtelelafv
Phosphatase ptp-2.AA Subfamily.N9.PD 449-580 38 2.9e-29 93.7 In-house 140-273 (275) Show / Hide 
Range on Protein: 449-580
Range on HMM: 140-273/275
Sequence Identity: 38% (53 aa)

SYILRTLVMK--KGKDTREIRQLQYLTWPDHGCPLHPYAVLNFLEDVDREYDYFNA---QPIAASLPQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVGL
|  |.|..|  | ...|..   |.|.|||.| |    ..|..|| | ..   .     .. .  | . |||||||||||||||   ||  |.....||  
dykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdeskghlsgPPivvhcsaGiGrtGtfitldiclarleevgt

lcpMDVYKMVKYVRTYRSGLVQTEQQYQFLYKALAFY
  .|| . ||..|| |.  .||..||.| |.|.  | 
---vdvvetvkllrtqrafsiqtpeqyefcylavley
Phosphatase ptp-2.AA Subfamily.N_Choan_2.PD 292-428 34 7.2e-29 92.1 In-house 21-151 (266) Show / Hide 
Range on Protein: 292-428
Range on HMM: 21-151/266
Sequence Identity: 34% (48 aa)

NAEKNRYKNIVPFDHTRVILTDRPNTPGSDYINASYVRfensqrtknVTFACEKSFIATQGCLETTISDFWSMVWQENSRVIVMPT-MENERKEKCARYW
|.. |||..|.|  .|||.| .  ... . |||| |||              .|..||..| |.||...|| |.|.|... ||| |.|.. ..||.||||
nkrlnRyndiLPsPatRvrleeleedsataYinAnyvr---------GfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYW

PAEVNKPEVH--GDISLTCTIERKVQRAVSDEVKAELEQE
||...      |.|. . . |.| .  .  ... | ..| 
paepkekvkladgkikvlalseekeegyiltrlrlekkge
Phosphatase ptp-2.AA Subfamily.N13.PD 450-579 35 2.3e-28 90.8 In-house 139-256 (259) Show / Hide 
Range on Protein: 450-579
Range on HMM: 139-256/259
Sequence Identity: 35% (44 aa)

YILRTLVM--KKGKDTREIRQLQYLTWPDHGCPLHPYAVLNFLEDVDReydyfnaqpIAAslPQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVGllcPM
. .|.| .  .. ...||. .|.. .||||| | ..  ...|. .| .         ..    .|||||||||||||.|.....|..|. .....|| ..
fvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrl---------lqt--dagPivvhcsaGiGrsGvlitidvvlglierdk---ef

DVYKMVKYVRTYRSGLVQTEQQYQFLYKALAF
|. .|  | |.|||..|| | |||.       
dvkeivrklreqrqgvvqtkdqyifvykaile
Phosphatase ptp-2.AA Subfamily.RC.PD 449-580 35 2.7e-28 90.4 In-house 156-286 (288) Show / Hide 
Range on Protein: 449-580
Range on HMM: 156-286/288
Sequence Identity: 35% (45 aa)

SYILRT--LVMKKGKDTREIRQLQYLTWPDHGCPLHPYAVLNFLEDVDREYDYFNAQPIAASLPQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVGLlcp
.||||   || || ||.||. |.|| .|.... | .|  .|.... | ..    .          .|..|||..| .|||. . |.|||. ...||...|
dyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeek---

MDVYKMVKYVRTYRSGLVQTEQQYQFLYKALAFY
| .|  |...|..|.||..||..|. .       
vdvfqvvkklrkarplmvsveeqyillydvlvet
Phosphatase ptp-2.AA Subfamily.RK.PD 442-578 31 8e-28 88.7 In-house 137-263 (267) Show / Hide 
Range on Protein: 442-578
Range on HMM: 137-263/267
Sequence Identity: 31% (43 aa)

ELNGDGISYILRTLVMKK-GKDTREIRQLQYLTWPDH-GCPLHPYAVLNFLEDVDREYDYfnaqpiaasLPQGPIVVHCSAGIGRTGTVLVLDALLNQVK
||. | .. |.|   . .  ...||.||.|.|.||.. . | .  ..|...  |..  .            .|.|||||.|| ||.|| ...|.|. ...
eldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqee---------eeeGrivvhClaGaGrsGtfiaidivlemie

KVGLlcpMDVYKMVKYVRTYRSGLVQTEQQYQFLYKALA
 |.   .||...|| .|.... .|.||.||.|.| .   
regv---vdvfnavktlrnrkvnmveteeqykfvydvil
Phosphatase ptp-2.AA Subfamily.N1.PD 280-426 32 1.4e-27 88.2 In-house 16-150 (268) Show / Hide 
Range on Protein: 280-426
Range on HMM: 16-150/268
Sequence Identity: 32% (49 aa)

QYLSKREGRRPVNAEKNRYKNIVPFDHTRVILTDRPNtpgsDYINASYVRFENSQRtknvtfacekSFIATQGCLETTISDFWSMVWQENSRVIVMP--T
. |..|| ..| | ..|||... |.||.|..| .  .    |||||| | .|. .|          ..| ||| |  |.. || |||..||. ..|    
keletreaklpenrglnryrdvspydhsrikleradv----dyinaslveleeakr----------rYiLtqGPLphtadHFWqmvWeqnskavimLnkv

MENErKEKCARYWPAEVNKPEVHGDI-SLTCTIERKVQRAVSDEVKAELE
.|.. . ||| ||| | ...|.  .  .|. .. .. ..      . |||
vEkn-qikCaqywpqeeeeaellleetklkvkliseerksyflvrlleLe
Phosphatase ptp-2.AA Subfamily.N14.PD 267-396 34 2.3e-27 87.2 In-house 5-122 (275) Show / Hide 
Range on Protein: 267-396
Range on HMM: 5-122/275
Sequence Identity: 34% (45 aa)

EFDRLSQEALPAEQYLskreGRRPVNAEKNRYKNIVPFDHTRVILTDRPNTpGSDYINASYVRFENSQRtknvtfacEKSFIATQGCLETTISDFWSMVW
|..|.... . |. .     .. |.||||||.|...|....|| |.   ..  ..||||| ..   . .        |.|.|..|| ||.|.||| |||.
eyeripkkredallst----aklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggk--------ersyivaqgPleltvqdfwqmvw

QENSRVIVMPTME-NERKEKCARYWPAEVNK
.. ..||| | | .. |||. .|.| . .| 
eqgvqlivmlteeeedgkeksfkylPklesk
Phosphatase ptp-2.AA Subfamily.N14.PD 451-582 39 3.3e-27 86.8 In-house 145-275 (275) Show / Hide 
Range on Protein: 451-582
Range on HMM: 145-275/275
Sequence Identity: 39% (50 aa)

ILRTLVMK--KGKDTREIRQLQYLTWPDHGCPLHPYAVLNFLEDVDREYDYFNAQPIAASLPQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVGllcPMD
| ..| .|    |. |..  |||  |||||.|  .   |.|||.|.     .| .  ..   . |..||||||.|||| ... | |.. ....|. |...
ittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvkeskPPvlvhCsaGvGrtGvlilsdlliatlehne---eid

VYKMVKYVRTYRSGLVQTEQQYQFLYKALAFYLK
 .|. |  ||||  ||.|.||.|  |||      
ikkvlarLrkqrmllvqtlaqykfvykvlikylk
Phosphatase ptp-2.AA Subfamily.N3.PD 448-576 41 5.1e-27 86.1 In-house 138-255 (261) Show / Hide 
Range on Protein: 448-576
Range on HMM: 138-255/261
Sequence Identity: 41% (53 aa)

ISYILRTLVMKKGK--DTREIRQLQYLTWPDHGCPLHPYAVLNFLEDVDREYdyfnaqpiaaSLPQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVGLLC
||.|| ||.|. .  . |.| ||||| ||||| | ..  .|.|.| | .            |  . |.|||||||||||| ...|.  |  ..   . |.
ksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklr----------sgkeePvvvhCsaGigrtGvlilletalalieaaepvy

PMDVykmVKYVRTYRSGLVQTEQQYQFLYKA
|.   |. .|  |. ||||..||.|. .|  
pldi---vrtmrdqramlvqtvsqykfvCea
Phosphatase ptp-2.AA Subfamily.R_Sponge_2.PD 449-580 32 6.6e-27 86.0 In-house 138-260 (262) Show / Hide 
Range on Protein: 449-580
Range on HMM: 138-260/262
Sequence Identity: 32% (43 aa)

SYILRTLVMKK---GKDTREIRQLQYLTWPDHGCPLHPYAVLNFLEDVDREYDyfNAQpiaaslpQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVGLlc
||.|.| ..|    .......| ....||.|..| .  ..|.....| |.    . .       ...|.|.||.|.||||| ..||..|...|. .    
dyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqk--ksg-------nkaitvvCsdgvgrtGtfialdsvlerlkaeee--

pMDVYKMVKYVRTYRSGLVQTEQQYQFLYKALAFY
.||....| .|| | ||||...||.|...||. | 
-idvfevlktlrtkriglvqdaaqYvfihdalley
Phosphatase ptp-2.AA Subfamily.RK.PD 264-408 32 1.1e-26 85.0 In-house 2-134 (267) Show / Hide 
Range on Protein: 264-408
Range on HMM: 2-134/267
Sequence Identity: 32% (47 aa)

ISEEFDRLSQeALPAEQYLSKREGRRPVNAEKNRYKNIVPFDHTRVILTDRPNTpGSDYINASYVrfensqrtknVTFACEKSFIATQGCLETTISDFWS
. |||. | .   |  |  .   . .. | ||||...|...|...|.|.   .   ||||||...           ..   . ||.||| |. |. ||| 
lkeefetlns-vtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaali----------dsykrpaafivtqgPlqetvkdfWr

MVWQENSRVIVMPTME-NE-RKEKCARYWPAEVNKpeVHGDISLTCT
.|..||.  ||| |    |  . || .||| . ..   .||| ... 
lvydencasivmlteldvevgrvkClkyWPedtev--rygdikvelv
Phosphatase ptp-2.AA Subfamily.N_Choan_2.PD 449-581 33 1.5e-26 84.5 In-house 138-265 (266) Show / Hide 
Range on Protein: 449-581
Range on HMM: 138-265/266
Sequence Identity: 33% (46 aa)

SYILRTLVMKKGKDTREIRQLQYLTWPDHGCPLHPY------AVLNFLEDVDREYDYFNAQpiaaslpqGPIVVHCSAGIGRTGTVLVLDALLNQVKKVG
|||. | ..|...||...  .| |||||| | ..        .|. |..| |  . .. .        .|..||||||.|||||....|  .. ... . 
gyiltrlrlekkgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldka--------ePllvHcsaGvgRtGtliaiDiavrlLeetk

llcPMDVYKMVKYVRTYRSGLVQTEQQYQFLYKALAFYL
   .|| .... .| .|  |||. .||..||||.. |  
---kvdvlaiieelRkdRmalvqhpeqyellykavveya
Phosphatase ptp-2.AA Subfamily.N23.PD 449-578 28 1.5e-25 81.3 In-house 221-346 (350) Show / Hide 
Range on Protein: 449-578
Range on HMM: 221-346/350
Sequence Identity: 28% (36 aa)

SYILrTLVMKKGKDTREIRQLQYLTWPDHGCPLHPYAVLNFLEDVDREYdYFNAQPIAASLPQGPIVVHCSAGIGRTGTVLVLDALLNQVK-KVGLLcpm
..| .| ... .  |.. .|.. ||...| |  |  .|.||..|.  |   . .  ... .. ||..|||||.|||||. |. . ..... .|..   ..
ervl-hlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetay-aqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagngii---

DVYKMVKYVRTYRSGLVQTEQQYQFLYKALA
 ..|. .|  |   ||.......||.|    
niprvvrrlrqqRkymvqkkvilkklyeavl
Phosphatase ptp-2.AA Subfamily.N20.PD 265-397 44 4.4e-25 80.1 In-house 3-119 (257) Show / Hide 
Range on Protein: 265-397
Range on HMM: 3-119/257
Sequence Identity: 44% (59 aa)

SEEFDRLSQEALPAEQylskREGRRPVNAEKNRYKNIVPFDHTRVILTDrpntpGSDYINASYVRFENSQRtknvtfacEKSFIATQGCLETTISDFWSM
.||  |  . || |       | .| | |||||..|.|.| ||| |         |||||||.|  |           |  .||||| | .|| ||| ||
mqefmalelknlpgef----nsgnqpsnreknryrdilpydstrvplgk-----skdyinasyirivncge--------eyfyiatqgpllstiddfwqm

VWQENSRVIVMPTMENERK-EKCARYWPAEVNKP
 ..|| || | | | |    || .|||  ..|| 
vlennsnviamitreieggiikcyhywpislkkp
Phosphatase ptp-2.AA Subfamily.N_Nematode_4.PD 292-424 37 7.2e-25 79.2 In-house 26-144 (264) Show / Hide 
Range on Protein: 292-424
Range on HMM: 26-144/264
Sequence Identity: 37% (49 aa)

NAEKNRYKNIVPFDHTRVILTDRPntPGSDYINASYVRFEnsqrtknvtfaCEKSFIATQGCLETTISDFWSMVWQENSRVIVM-PTMENERKEKCARYW
|..||||..|.  |.|||.| .|.  |  ||| ||..|              .  .|.||| |. |.|||| ||..|   |.||....|  ||||||.| 
nsdknryadilcidetrvvlknrd--pdndyihaswmrmP-----------dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryy

PAEVNKPEVHGDISLTCtIERKVQrAVSDEVKAE
. .|  ..|.  .|  .|.|.. ...| .     
peksekvvkfGkyritl-vekkee-viadvilns
Phosphatase ptp-2.AA Subfamily.RN.PD 283-394 40 1.3e-24 78.2 In-house 18-121 (264) Show / Hide 
Range on Protein: 283-394
Range on HMM: 18-121/264
Sequence Identity: 40% (45 aa)

SKREGRRPVNAEKNRYKNIVPFDHTRVILTDRPNTPGSDYINASYVRfENSQRtknvtfacEKSFIATQGCLETTISDFWSMVWQENSRVIVMPTMENE-
.|  .... |..|||.|...|.||.|| |... ..  ||||||| .  ..  |        . ..||||| | .||.||| |||.. . |||.|  .|  
tkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasail-dhdpr--------apayiatqgplsstiadfwqmvweqGvvvivnltrleee

RKEKCARYWPAEV
 ..|.|||| |  
gvkqckrywpdeG
Phosphatase ptp-2.AA Subfamily.N1.PD 452-577 40 1.6e-24 78.1 In-house 144-263 (268) Show / Hide 
Range on Protein: 452-577
Range on HMM: 144-263/268
Sequence Identity: 40% (51 aa)

LRTLVMK--KGKDTREIRQLQYLTWPDHGCPLHPYAVLNFLEDVDREydyfnaqpIAASLPQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVGLLCPMDV
.|.| ..  . ..|||| . .| |||| | |  | |.|.||  | .          . |   ||.|.||||||||.||. ..|..| .. | ||  .|. 
vrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvres--------gsLssdvgpavihCsagigrsgtlslvdtclveiektgdlnavdi

YKMVKYVRTYRSGLVQTEQQYQFLYKAL
| .  .| || ||.|| .| .| | |. 
kkvLlelRkyRvGLiqtpdqLrFsyiai
Phosphatase ptp-2.AA Subfamily.RC.PD 281-412 28 1.6e-22 71.4 In-house 15-153 (288) Show / Hide 
Range on Protein: 281-412
Range on HMM: 15-153/288
Sequence Identity: 28% (43 aa)

YLSKREGRRPVNAEKNRYKNIVPFDHTRVIL-------------------TDRPNTPGSDYINASYVrfensqrtknVTFACEKSFIATQGCLETTISDF
. .....|.. | .|||| ...|.|. || |                    |     ||.|||||..           ..   . .||.|| |.|. |||
krtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfi----------dsykkpekyiaaqGplketvddf

WSMVWQENSRVIVMPT-MENERKEKCARYWpaeVNKPEVHGDISLTCTIERK
 |....  .|||| | ...  .||||.||    .  . .||. .    . | 
wrmiferkvkvivmltelkeGdrekcaeyw---eeGkrayGdvevdlkdtdk
Phosphatase ptp-2.AA Subfamily.RN.PD 450-578 33 2e-22 71.0 In-house 142-260 (264) Show / Hide 
Range on Protein: 450-578
Range on HMM: 142-260/264
Sequence Identity: 33% (43 aa)

YILRTLVMK--KGKDTREIRQLQYLTWPDHGCPLHPYAVLNFLEDVDREYDYfnaQpiaaSlpqGPIVVHCSAGIGRTGTVLVLDALLNQVKKvGlLCPM
|..|.. .|  . ..|| . |. .|.||..|.|  . ..|.|   |.. |     .    |    |||||||.| ||||. ...| .|....|| .  .|
ylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrG---r----s---cpivvhcsdGaGrtGvyilidlvlerllk-G-vkei

DVYKMVKYVRTYRSGLVQTEQQYQFLYKALA
.   ....|  |.|||.|..|..| ..|.| 
diaatlehlrdqrpglvktkdqfefaltava
Phosphatase ptp-2.AA Subfamily.N20.PD 455-576 35 5.2e-20 63.5 In-house 145-251 (257) Show / Hide 
Range on Protein: 455-576
Range on HMM: 145-251/257
Sequence Identity: 35% (43 aa)

LVMKKGKDTREIRQLQYLTWPDHGCPLHPYAVLNFLEdvdreydYfnaqpIAASLPQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVgllCPMDVYKMVK
.| |    .. ..|||.  ||||| |    ......        |        |   ||.|||||||||||| .|..| ..  . |    | ...  .| 
vvekstgtshsvkqlqftkwpdhgtpasadsfikyir-------y-----arkshltgpmvvhcsagigrtgvflcvdvvfcaivkn---csfnimdiva

YVRTYRSGLVQTEQQYQFLYKA
 .|  |||.|||..||.| |  
qmreqrsgmvqtkeqyhfcydi
Phosphatase ptp-2.AA Subfamily.N_Nematode_5.PD 292-411 29 6.9e-18 56.1 In-house 25-130 (258) Show / Hide 
Range on Protein: 292-411
Range on HMM: 25-130/258
Sequence Identity: 29% (35 aa)

NAEKNRYKNIVPFDHTRViltdRPNT-PgSDYINASYVRFENsqrtknvtfaCEKSFIATQGCLETTISDFWSMVWQENSRVIVMPTMENERKEKCARYW
| .|||.|..   |.|||    ...  . ..|||||......          .||..| ||  | .|..||| || ||.   .|. ....| ||.   ..
nlkknrskdvkilDetrV----kltded-dsYinaskikldd----------lekkliltQlPlpdteedFWrmvyqekitsvvllvedeelketavsff

PAEVNKPEVHGDISLTCTIER
| | ..   .|..  ...   
pletgdylnlgkmfinnrkve
Phosphatase ptp-2.AA Subfamily.N_Nematode_6.PD 451-581 29 2.6e-16 51.2 In-house 139-252 (253) Show / Hide 
Range on Protein: 451-581
Range on HMM: 139-252/253
Sequence Identity: 29% (37 aa)

ILRTLVMKKGKDTREIRQLQYLTWPDHGCPLHPYAVLNFLEDVDREydyfnaqpiaaslpQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVGLlcpMDVY
..|.|..   .. ...  ||||| |    . | .|. | ..              . |||||||||.|||||. ..  .|. ....     ..| ...  
rslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvkkd--------------kkPivvhCsaGvGrtGtlaliliilealrlpdf---qgvk

KMVKYVRTYRSGLVQTEQQYQFLYKALAFYL
.|  |   |||| || . .. .  ||     
dllvklreerfravqtevqylyalrcvleyl
Phosphatase ptp-2.AA Subfamily.N_Nematode_egg.PD 285-407 29 6.1e-16 50.0 In-house 19-132 (257) Show / Hide 
Range on Protein: 285-407
Range on HMM: 19-132/257
Sequence Identity: 29% (37 aa)

REGRRPVNAEKNRYKNIVPFDHTRVILTDRPNTPGSDYINASYVRfensqrTKNVtFaceKSFIATQGCLETTISDFWSMVWQENSRVIVMPTMENERkE
..     . || | | .   . .|| |  |      |.| | .|.       | . .     || .|  |  |  ||| ||.||. . ||| |   |  |
ttaasdnylekarskrvhckessrvklelrrGqylddfihanrvk------Gkpl-l---nefilaqaplkntvedfwrmvfqekvqyivmltsakes-e

KCARYWPAEVNKPEVH--GDISLTC
.|  |||   ... |   | . ...
rceyywpkaeseslvtvpGslrien
Phosphatase ptp-2.AA Subfamily.N_Nematode_6.PD 292-420 30 2e-15 48.3 In-house 24-135 (253) Show / Hide 
Range on Protein: 292-420
Range on HMM: 24-135/253
Sequence Identity: 30% (39 aa)

NAEKNRYKNIVPFDHTRVILTDRPNTpgsdYINASYVRFENSQRTknvtfaceksFIATQGCLETTISDFWSMVWQENSRVIVMP-TMENERKEKCARYW
. ..|||.||  .| .|. |.| ..     || |..|.    .|           .| ||. ||.|| .|| |.    .  |||. .. |||.|.| . .
fkdrnrytniqCcdagrlkladdedf----yihanlvkistkprr----------lictqaplegtieefwkmilssgveyivmlcelvekgkeksaeyl

PAEVNkpeVHGDISLTCTIErKVQRAVSDE
|     .  |.  ||.  |..|   |    
sdkvG---darkitklctvi-kigrkdidk
Phosphatase ptp-2.AA Subfamily.N_Nematode_4.PD 466-578 27 2.2e-15 48.1 In-house 163-260 (264) Show / Hide 
Range on Protein: 466-578
Range on HMM: 163-260/264
Sequence Identity: 27% (31 aa)

IRQLQYLTWPDHGCPLHPYAVLNFLEDVDREydyfnAQpiaaslpQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVGllcPMDVYKMVKYVRTYRSGLVQ
.. .|.  |.|.  || . .|....  |  .      .       ..|||||||||.||| |.. .|    ... ..    ..|..|. .|. | . ||.
vkhvqvdwwrdqvaPldaapviklykavkkk-----kk-------ekPivvhcsaGvGrtatlvGidyatirirens---eievldivrelramrlkavq

TEQQYQFLYKALA
. |. ||.  |. 
shlqflfllvvli
Phosphatase ptp-2.AA Subfamily.N_Nematode_5.PD 465-582 23 1.4e-13 42.0 In-house 153-258 (258) Show / Hide 
Range on Protein: 465-582
Range on HMM: 153-258/258
Sequence Identity: 23% (28 aa)

EIRQLQYLTWPDHGCPLHPYAVLNfledvdREYDYF-------NaqpiaaslpqGPIVVHCSAGIGRTGTVLVLDALLNQVKKVgllCPMDVYKMVKYVR
..  .. ||...  | . ..|..      |.   .       |           |.||....|.||.||.|.|..  .|...... ...| .|. | | |
fakvyhlttWkkkkvPdkvkkvik------raiekvlskkqgkn----------apvvvvsdlGlgRagtflllsvaieqlnng---kepnideilkkir

TYRSGLVQTEQQYQFLYKALAFYLK
.. .|| ..|.|...|.|       
sqRpgavesliqyasvyaavldyik
Phosphatase ptp-2.AA Subfamily.N_Nematode_eak.PD 280-407 27 1.1e-11 35.9 In-house 14-130 (281) Show / Hide 
Range on Protein: 280-407
Range on HMM: 14-130/281
Sequence Identity: 27% (36 aa)

QYLSKREGRRPVNAEKNRYKNIVPFDHTRVILTDRPNTPgSDYINASYVRFENsqrtknvtfaCEKSFIATQGCLETTISDFWSMVWQENSRVIVMPTME
. ||.|...|  . ..||  .|||.|.  | ||     .   ||||| . | .            . .| |    |. .  || || ...|  ||.   .
rllsirvtarleavnrnrvvkivpqdrylvrltssqlnr-dGyinaslaefse----------vGrkyiltGiasedkvfafwqmvleqkspaivqlled

NERK-EKCARYWPAEVnKPEVHGDISLTC
 | | ||  .|.| .  .   .| . ...
veekleksdkyfpdkt-evlkyGildver
Phosphatase ptp-2.AA Family.DSP.PD 444-585 19 1.4e-11 35.7 In-house 148-249 (387) Show / Hide 
Range on Protein: 444-585
Range on HMM: 148-249/387
Sequence Identity: 19% (27 aa)

NgdgisyilrtlvmkkgkdTREIRQLQYlTWPDHGCP-LHPYavlnFLEDVDreydYFNAQPiAaslPQGPIVVHCSAGIGRTGTVLVldALLNQVKKVG
.                  . .|. |..  ..||..| |. .    | ...|    . . ..     ..| ..||| ||.||.||. .  | | .... |
k------------------elgikylri-pidDhnapplenl----fekaid----fieegn-d---skgvVlVHCkaGkgRsgtlii--aYlmkseglt

LLcpmDVYKMVKYVRtyrSGLVQTEQQyqFLYKALAFYLKNNN
    . ...|. .|   .| .. .|.  || .  ... .. . 
le---ealdwvrskR---pgvitpnqg--flkqlkdlekeklk
Phosphatase ptp-2.AA Subfamily.PTPDC1.PD 505-574 30 1.9e-07 22.1 In-house 160-221 (229) Show / Hide 
Range on Protein: 505-574
Range on HMM: 160-221/229
Sequence Identity: 30% (21 aa)

IAASLPQGPIVVHCSAGIGRTGTVLVldALLNQVKKvgllcpMDVYKMVKYVRTYRSGLVQTEQQYQFLY
.. .| .| | ||| || |||| ..   . |  .|.      ..  . .| ||  |.  .|| .| ... 
vdfaleegkiavHCHAGlGRtGvlia--cylvyakr------ltaeeaiklvrskrpksiqtreqvelve
Phosphatase ptp-2.AA Subfamily.CDC14.PD 511-574 32 1.9e-07 22.4 In-house 198-252 (258) Show / Hide 
Range on Protein: 511-574
Range on HMM: 198-252/258
Sequence Identity: 32% (21 aa)

QGPIVVHCSAGIGRTGTVLVldALLnqVKKVGllcpMDVYKMVKYVRTYRSGLVQTEQQyQFLY
.| |.||| ||.|||||..   . |  .|. .    .    .. ..|  | | | . || ..|.
eGaiavhCkaGLGrtgtlig--cyl--ikhyr----ftaaetiawlriarPGsvigpqq-tylv
Phosphatase ptp-2.AA Subfamily.N_Nematode_egg.PD 512-582 22 1.4e-06 19.3 In-house 188-257 (257) Show / Hide 
Range on Protein: 512-582
Range on HMM: 188-257/257
Sequence Identity: 22% (16 aa)

GPIVVHCSAGIGRTGTVLVLDALLNQVKKvGLLCPMDVYKMVKYVRTYRSGLVQTEQQYQFLYKALAFYLK
|.||..  |. ...|.. ..  | .. . | .    | . |...|  |   |..  .| |.|. ..|... 
kpvvvqdilGvskaatlvaieiallsllr-Gpitkslvlravvflrlrrrlsvesvllylfvyrlvlffir
Phosphatase ptp-2.AA Subfamily.DSP23.PD 510-573 31 4.2e-06 18.2 In-house 65-120 (128) Show / Hide 
Range on Protein: 510-573
Range on HMM: 65-120/128
Sequence Identity: 31% (20 aa)

PQGPIVVHCSAGIGRTGTVLVLdaLLnqVKKVGllcpMDVYKMVKYVRTYRSGLVQTEQQYQFL
.... |||  |.|||||.|     |  ||. |    .   . .  ||  | | ..| .| . . 
keeavgvhcalGlGrtGtllac--yl--vkeeg----laaddaiaevrkrrkGsietveqekav
Sequence
Name Sequence Type Origin Length Description Download
ptp-2.AA Protein None 668 None Fasta, JSON
ptp-2.NA RNA None 2004 None Fasta, JSON
ptp-2.AA.PD_263-582 Protein Phosphatase Domain None 320 None Fasta, JSON