R06B10.1
Species: C.elegans
Alias: R06B10.1
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: R_Nematode_3
Protein domain

Protein domains of R06B10.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
WSN R06B10.1.AA WSN 97-168 44 1.1e-29 109.72 Pfam 1-72 (72) Show / Hide
Range on Protein: 97-168
Range on HMM: 1-72/72
Sequence Identity: 44% (32 aa)

EELSKSVNQMHMISRIINGIYLQQSLVNNTIPSEELISELLNIGSLTTSQIVGINGAKLTTVVDQINQLSTK
..|......|.||||..||||||| | ...||....|.||||||| . |||..|. .||. ....||.... 
SNLQTIYERMQMISRVTNGIYLQQGLIDGSIPIDDVIAELLNIGSGNFSQIMNIDPDKLDKIDEHINKMHEL

WSN R06B10.1.AA WSN 97-168 33 3.4e-29 104.23 SMART 1-72 (72) Show / Hide
Range on Protein: 97-168
Range on HMM: 1-72/72
Sequence Identity: 33% (24 aa)

EELSKSVNQMHMISRIINGIYLQQSLVNNTIPSEELISELLNIGSLTTSQIVGINGAKLTTVVDQINQLSTK
..|......|.|..|..|.||||. |.|..||....|.||||||.....|.  |.  ..|......|.....
SKLQTIIENMQMLARVTNAIYLQAGLINGSIPIDDVIAELLNIGTIDPVQFSDIMNVDPTKIDKWMNKMKER

Phosphatase R06B10.1.AA PTPc 880-1149 20 2.4e-24 88.1 SMART 1-308 (308) Show / Hide
Range on Protein: 880-1149
Range on HMM: 1-308/308
Sequence Identity: 20% (68 aa)

YIKGQVLWCCQETVTILT-------DWVIGHEKDQ------RY--TVSMFANSQNALVGYGKR----FVDGYIHASKVIFP-NNLRMILTQSPQHKTKTR
 .. .    ...|...|.       .. ... .        ||   .  .  .   |    ..    . ..||.|. . .. .. |.|.|| |.      
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPL------

NSTIEKFWWMAMQERSKSIVQLCENME--PTHNLDWDTSEACAEYVPLAEGGEIKFDGGSVRCVQKSMEFDDEGEVRQLLVKFDDQ---------PEFTI
 .||| ||.|  |.....|| ||. ||  .  | |    | |. | |.    . .... .| |. .     |.  .|.. |.....          . |.
PHTIEDFWRMVWQQKCHIIVMLCNCMEKCT-ENRDQNGREKCHQYWPDE---PMTYGHITVTCKSEEKCP-DDYTMRTFEVTNTGCNCKYSMACSETRTV

EHLWYRGWKDRLVPESPKIMLDLLDKVNTN-----------------------TTPVIVHCKNGISKSACFAYIELACQMIPGLTSDQSDRDILYVLLRM
 |..| .|.|. |||||. .||.. .|..                        |.|..||| .|.. ...|. |. .||.|          ||. .. .|
THYHYTNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN-------VDIFQIVKMM

RAE---CFPNYQLYSFALYGVFMRLME
| .   .. . . |.| .| . ... .
RNQRPGMVQTEEQYIF-CYRCILEYIK

Phosphatase R06B10.1.AA Subfamily.R_Nematode_3.PD 881-1148 38 7.79999999999e-101 327.9 In-house 2-267 (267) Show / Hide
Range on Protein: 881-1148
Range on HMM: 2-267/267
Sequence Identity: 38% (103 aa)

IKGQVLWCCQETVTILTDWVIGHEKDQRYTVSMFANSQNALVGYGKRFVDGYIHASKVIFPNNLRMILTQSPQHKTKT--RNSTIEKFWWMAMQERSKSI
.. .. ........  |...  ...|.|..|.........|.|||||| |..|||. | .||.|..|||||||.|.|.  ..|||||||||..||.....
lekafekiaklakknatslskkvsedrrvevpllektrvvLkgygkrfkddfihAnvvecpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqv

VQLCENMEpthnLDWDTSEACAEYVPLAEGGEIKFDGGSVRCVQKSMEFDDEGEVRQLLVKFDDQPEFTIEHLWYRGWKDRLVPESPKIMLDLLDKVNTN
|.||...|     |....|.|.||.|....||.||.|.||.|.....|.... | |.| |.|....|||..||.|.|||.. .||.|| .|.|...|...
vmlcdfve----edgeeeekcseYypekvdgelkfegvsvkctdikkelsedvekrtlvvtfekkkeftvthllykgWkelnapeepkealelikfveks

TTPVIVHCKNGISKSACFAYIELACQMIPGLTSDQSDRDILYVLLRMRAECFPNYQLYSFALYGVFMRLM
.|||.|||..|||.||..|.|||..|.|   ..... ..... | ..||... ... ..|...|....||
ktpvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgilkllm

Phosphatase R06B10.1.AA Y_phosphatase 903-1145 25 2.5e-58 204.89 Pfam 1-243 (243) Show / Hide
Range on Protein: 903-1145
Range on HMM: 1-243/243
Sequence Identity: 25% (66 aa)

HEKDQRYT-VSMFANSQNALVGYGKRFVDGYIHASKVIFP--NNLRMILTQSPQHKTKTRNSTIEKFWWMAMQERSKSIVQLCENMEPTHNLDWDTSEA-
. .  ||. .  . ..   | ... .. . ||.|. . .|  |. ..|.|| |..      .||| ||.|  |.....||.||..||  .      .|  
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMP------HTIEDFWRMVWQQKCTCIVMLCNCMEMGR------DEKT

CAEYVPL-AEGGEIKFDGGSVRCVQKSMEFDDEGEVRQLLVKFDD---QPEFTIEHLWYRGWKDRLVPES-PKIMLDLLDKVNTNTT-------PVIVHC
|..| |. .||....... .| || . .  ...  ||.. |.. .   |.. |. |..| .|.|. |||| || |||....|.. ..       |..|||
CHQYWPDNKEGQPMTYGDFQVTCVSEEH--CPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHC

KNGISKSACFAYIELACQMIPGLTSDQSDRDILYVLLRMRAECFPNYQLYSFALYGVFM
 .|.. ...|. |. .||..    .  .  .|.  . ..|. .. ... | |    .  
SAGCGRTGTFCAIDIMCQQMEHEGTV-DIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

Phosphatase R06B10.1.AA Subfamily.N_Nematode_1.PD 925-1111 29 3.4e-28 89.7 In-house 47-229 (265) Show / Hide
Range on Protein: 925-1111
Range on HMM: 47-229/265
Sequence Identity: 29% (58 aa)

GKRFVDGYIHASKVIFPNN-LRMILTQSPQHKtktrnsTIEKFWWMAMQERSKSIVQLCENMEPTHnldwdtsEACAEYVPLAEGGEIKFDGGSVRCV--
.     ||||  |  | |  |.| .|.| .|      ||..||.|..||. ..|| ||. .| ..         |||| |..|| ...|. .. ...   
eeplpsdyihanyvgtptnpkrficaqaPldk------tiadfwymvlqekveaivmlckliekgk-------kkcaeyfpakegeklefkekgqkitve

----QKSMEFDDE-GEVRQLLVKFDDQPEFTIEHLWYRGWKDRLVPESPKIMLDLLDKVNTNTTPVIVHCKNGISKSACFAYIELACQ-MIPGLTS
    | .| |.|  .| .| |..  . . ...|. .  | || ||.    .|.||..|.....|..|||  || ..     ||. .. .. | .  
nslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrgskgPivvhCsaGiGrtGtivaieyildkllegkqi

Phosphatase R06B10.1.AA Subfamily.R_Nematode_2.PD 884-1100 28 4.4e-28 89.3 In-house 10-214 (261) Show / Hide
Range on Protein: 884-1100
Range on HMM: 10-214/261
Sequence Identity: 28% (61 aa)

QVLWCCQETVTILTDWVIGHEKDQRYTVSMFANSQNALVGYGKRFVDgyIHASKVIFPNN-LRMILTQSPQhktktrNSTIEKFWWMAMQERSKSIVQLC
.| .  ..  .. ..    ..  .||      ..    |    . |.  |||  |  ..|  | | ||.|       . | ||| |..||    || ||.
svvvatidkesvtesaaylpkdkhRypdvPCkpetavevivdgkrvp--ihanwvptagnpkrfiatqgPl------entsedfWamviqekvekivmlc

ENMEPthnldwdTSEACAEYVPLAEGGEIKFDGGSVRCVQKSMEFDDEGEVRQLLVKFDDQ--PEFTIEHLWYRGWKDRLVPESPKIMLDLLDKVNTNTT
..|        . | |.||.|| .. .....  |.. |.. .  .|| |.|.| |.   .  .|..|. |  | || ||.| . . .||. |  .. |..
qkvek-------ekekceeYfpletsqkldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkksek

PVIVHCKNGISKSACFAYIE
||| .|| ..  |  .|   
PivvhCsaGiGRtmafigte

Phosphatase R06B10.1.AA Subfamily.N_Nematode_4.PD 904-1134 23 5.6e-24 75.9 In-house 27-247 (264) Show / Hide
Range on Protein: 904-1134
Range on HMM: 27-247/264
Sequence Identity: 23% (56 aa)

EKDQRYTvSMFANSQNALVGYGKRFVDGYIHASKVIFPNNLRMILTQSPQHKtktrnsTIEKFWWMAMQERSKSIVQLCENMEpthnldwDTSEACAEYV
.  ||.  ..   .. .|   .     ||||| .  |.. | | || | ..      |.. || |  .|. . .| ||. .|       .  | || |.|
sdknrya-dilcidetrvvlknrdpdndyihaswmrmPdkfryistqGPlke------tlsdfwhmvytekiavvvmlcdlie-------egvekcaryy

PLAEGGEIKFDGGSVRCVQKSMEFDDEGEVRQLLVKFDD----QPE--FTIEHLWYRGWKDRLVPESPKIMLDLLDKVNT--NTTPVIVHCKNGISKSAC
  ..   ||    .. |.|  |   .  .. | |   .     |   . ..|. .  |.|..|. .. ...|.  |.   . .|..|||  |. ..| . 
peksekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkkkkkekPivvhcsaGvGrtat

FAYIELACQMIpgltSDQSDRDILYVLLRMRAECFPNYQ
 |..| ..|     ..|. ..| .. ..||  .   |  
lvGidyatiri----renseievldivrelramrlkavq

Phosphatase R06B10.1.AA Subfamily.N_Nematode_6.PD 930-1128 29 3.7e-22 70.0 In-house 48-233 (253) Show / Hide
Range on Protein: 930-1128
Range on HMM: 48-233/253
Sequence Identity: 29% (59 aa)

DGYIHASKVI-FPNNLRMILTQSPQhktktrNSTIEKFWWMAMQERSKSIVQLCENMEpthnldwDTSEACAEYVPLAEGGEIKFdGGSVRCVQKSMEFD
| ||||. |   ... |.| ||.|       ..|||.|| |..   ...|| ||| .|       . .| .|||..   | .|. . .   .. . .  |
dfyihanlvkistkprrlictqapl------egtieefwkmilssgveyivmlcelve-------kgkeksaeylsdkvGdarki-tklctvikigrkdi

DEGEVRQL--LVKFDDQPEfTIEHLWYRGWKDRLVPESPKIMLDLLDKVNTNTTPVIVHCKNGISKSACFAYIELACQMIPglTSDQSDRDILYVLLR-M
   || |  .||  |..   ..|. .. | |  ||.| .  | ||  |  .. |..|||  |..   .| |. . . .   . |...   |.|.||  |.
dkilvrslkrivkagdeev-ivkhihWanWPdhGvPdsflsalrllsvvkkdkkPivvhCsaGvGrtGtlaliliilealr--lpdfqgvkdllvklree

RAE
   
rfr

Phosphatase R06B10.1.AA Subfamily.N5_RR.PD 960-1127 29 1.5e-21 68.0 In-house 78-241 (265) Show / Hide
Range on Protein: 960-1127
Range on HMM: 78-241/265
Sequence Identity: 29% (50 aa)

NSTIEKFWWMAMQERSKSIVQLCENMEpthnldwDTSEACAEYVPLAEGGEIKFDGGSVRCVQKSMEFDDEGEVRQLLVKFDDQPEFTIEHLWYRGWKDR
.||..|| |  ||... || | .  |          . ||.| | ||. ||.   | |    ...   .. .||.|..|.  . | ..| ||  | |. .
pntiadfWrmiyqeevqvivmltklke-------anrqkcavyfPdaedyeiserygdveikveeiverndysvrklvlkylerversvkhywytdWPdh

LVPESPKIMLDLLDKVNT-------NTTPVIVHCKNGISKSACFAYIELACQMIpgltSDQSDRDILYVLLRMRA
|.... .|||...|..       ...||.|||  || .  ||  |..|.. .     ...  |.| .  ..|   
ksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiaisiavrql----reeivvdvlkivcnlrl

Phosphatase R06B10.1.AA Subfamily.N3.PD 945-1138 27 1e-19 61.8 In-house 70-251 (261) Show / Hide
Range on Protein: 945-1138
Range on HMM: 70-251/261
Sequence Identity: 27% (53 aa)

RMILTQSPQHKtktrnsTIEKFWWMAMQERSKSIVQLCENMEPTHnldwdtsEACAEYVPLaEGGEIKFDGGSVRCVQKsmEFDDEGEVRQLLVKFDD-Q
| | || | .|      | ..|| |  ...|. || | ...|  .         | .| |  .. |..| . |||| ..  . . .  .|.|..|  . .
ryiatqGplak------takdfWqmvweqkstlivmlttlverGr-------vkChqyWPe-tedelefgefsvrceke--detksyvlrelvlkdketk

PEFTIEHLWYRGWKDRLVPESPKIMLDLLDKVNTN----TTPVIVHCKNGISKSACFAYIELACQMIPGlTSDQSDRDILYVLLRMRAECFPNYQLYSF
 | .| .| |  | |  ||.... .|.....|..     ..||.|||  || ..  .  .|.| ..|   . .    ||.  .||   .. . | |   
eerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlilletalaliea-aepvypldivrtmrdqramlvqtvsqykf

Phosphatase R06B10.1.AA Subfamily.N_Nematode_5.PD 930-1136 21 8.4e-19 58.8 In-house 49-246 (258) Show / Hide
Range on Protein: 930-1136
Range on HMM: 49-246/258
Sequence Identity: 21% (45 aa)

DGYIHASKVIFP-NNLRMILTQSPQHKTKtrnstiEKFWWMAMQERSKSIVQLCENMEPTHNLDwdtseacaEYVPLAEGGEIKFDGGSVRCVQKSMEFD
|.||.|||. ..  . ..|||| |. .|.      | || | .||. .|.| |.|. | ..           .. || .|....  ... .   . |.. 
dsYinaskiklddlekkliltQlPlpdte------edFWrmvyqekitsvvllvedeelketav--------sffpletgdylnlgkmfinnrkvevked

DEGEVRQLLVKFDDQPEFTIEHLWYRGWKDRLVPESPKIMLD-LLDKVNTNT----TPVIVHCKNGISKSACFAYIELACQMIPGLtSDQSDRDILYVLL
|    ..  ..  .  ...  .  ||.  ||.. | ..   . ||  ..    .||.|....|. ... |. ...|.. .    .     .||  .   |
ekkeytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgknapvvvvsdlGlgRagtflllsvaieqlnng-kepnideilkkir

RMRAECFPNYQLY
.. . ... |   
sqRpgavesliqy

Phosphatase R06B10.1.AA Subfamily.N12.PD 930-1127 23 9e-19 58.6 In-house 60-246 (270) Show / Hide
Range on Protein: 930-1127
Range on HMM: 60-246/270
Sequence Identity: 23% (45 aa)

DGYIHASKVIFPN-NLRMILTQSPQHKtktrnsTIEKFWWMAMQERSKSIVQLCENMEPTHnldwdtsEACAEYVPLAEGGEIKFDGGSVRCVQKSMeFD
..|| |. .  .. .|. | .|.|  |      |.. || | .. . . .| .|...|  .         |. | |   . |..|.  .|. .. . .||
sdyinanfikgvegkleyiaaqgPLpk------tlddfWrmiweknveivvmaCrevelgk-------kkCeryWpeegeeelefgefevtleeeka-vd

DEGEVRQLLVKFDdQPEFTIEHLWYRGWKDRLVPESPKIMLDLLDKVNT----NTTPVIVHCKNGISKSACFAYIELACQMIPGlTSDQSDRDILYVLLR
.  .|.| |... . . ... . |. | |. ||.|.| .|.|...|..    . .|..|||  |. .      |... ...... |.  ..|..|     
ddflirtLkveaq-kesrkvyqfhytaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellka-ekipeeldvfdlvle

MRA
   
lrk

Phosphatase R06B10.1.AA Subfamily.N6.PD 960-1106 25 2.5e-18 57.4 In-house 107-251 (295) Show / Hide
Range on Protein: 960-1106
Range on HMM: 107-251/295
Sequence Identity: 25% (39 aa)

NSTIEKFWWMAMQERSKSIVQLCENMEPTHNldwdtseACAEYVPLAEGGEIkFDGGSVRCVQKsmEFDDEGEVRQLLVKF--DDQPEFTIEHLWYRGWK
..|.. || |..|| |. || . ...|  .|        || | | .|  .  .   .|....   .  .. ..|...|.   .|... .|.. .. | |
kdtvsdFWrmvwqensrvivmttkevergkn-------kCarYWPdeetkke-tGvitvtsisE--kstadYtlRefsvshkdkdkeareifqyhfkaWP

DRLVPESPKIMLDLLDKVNTNT------TPVIVHCKNGISKSACFAYIELACQMI
  ||..|...|..|..||...       |..||| .|| .   |  |.   ..| 
dhgvpkdpgvvlnfledvnkkqeelekagpivvhcsaGiGrtGtfividivlkii

Phosphatase R06B10.1.AA Subfamily.N23.PD 931-1127 25 2.6e-18 57.2 In-house 132-326 (350) Show / Hide
Range on Protein: 931-1127
Range on HMM: 132-326/350
Sequence Identity: 25% (54 aa)

GYIHAS--KVIFPNNLRMILTQSPQHktktrnSTIEKFWWMAMQERSKSIVQLCENMEPTHnldwdtsEACAEYVPLAEGGEIKFDGGSVRCvqKSMEFD
|| |.  | . |    .| ||.|..      ||.  || | ....|. || | .. |  .         |..| | .||   .|.  .|.  ||..  ..
dyinatylkeltpmsPpfiatqgPia------stlaDFWlmvweqqssviVmltkevegnk-------lkcdqYwPidegetnlfgdlrvsl--kslrss

DEGEVRQLLVKFDDQP-EFTIEHLWYRGWKDRLVPESPKIMLDLLDKVNTNT-------T------PVIVHCKNGISKSACFAYIELACQMIPgltSDQS
   |.| ....|.    .. || .  | .  ||.||. .|..|..|.|         |      |.|.||  |. ..  |. .  | . .     ..   
egwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysairelt---agng

DRDILYVLLRMRA
.|. |. |.|.  
iiniprvvrrlrq

Phosphatase R06B10.1.AA Subfamily.N1.PD 931-1127 30 3.2e-18 57.2 In-house 53-244 (268) Show / Hide
Range on Protein: 931-1127
Range on HMM: 53-244/268
Sequence Identity: 30% (60 aa)

GYIHASKVIFPNNL-RMILTQSPQHKtktrnsTIEKFWWMAMQERSKSIVQLCENMEpthnldwDTSEACAEYVPLAEGG-EIKFDGGSVRCVQKSMEFD
|| || | ...   | |||| |  .      |.. || |  .. ||... | . .|         .  ||.| |  |   |....  . .| |. ..  |
dyinaslveleeakrrYiLtqGPLph------tadHFWqmvWeqnskavimLnkvvE-------knqikCaqywpqeeeeaellleetklkvkliseerk

DEGEVRQLLVK-FDDQPEFTIEHLWYRGWKDRLVPESPKIMLDLLDKVN------TNTTPVIVHCKNGISKSACFAYIELACQMIpGLTSDQSDRDILYV
|.| ..  ..|   .| |  |  | |  |||||. .|..| ||       .. .|...||. || .|. .. ..|   | |..  ||  ||| .|     
syflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsgtlslvdtclvei-ektgdlnavdikkv

LLRMRA
      
LlelRk

Phosphatase R06B10.1.AA Subfamily.N_Nematode_egg.PD 927-1111 28 3.3e-18 57.0 In-house 51-220 (257) Show / Hide
Range on Protein: 927-1111
Range on HMM: 51-220/257
Sequence Identity: 28% (53 aa)

RFVDGYIHASKVIF-PNNLRMILTQSPQHKtktrnsTIEKFWWMAMQERSKSIVQLCENMEPthnldwdtsEACAEYVPLAEGGEIKFDGGSV--RCVQK
...| .||| .|   |    .||.|.|         | | || | .||. . || |  ..|.         | |  | |||   ...  ||.   ...  
qylddfihanrvkGkpllnefilaqaplkn------tvedfwrmvfqekvqyivmltsakes---------erceyywpkaeseslvtvpGslrienlkv

SMEFDDEGEVRQLLVKFDDQPEFTIEHlWYRGWKDRLVPESPkimLDLLDKVNTNTTPVIVHCKNGISKSACFAYIELA-CQMIPGLTS
 . |    | .| .   |. |  .|| |   ..      ||   | .| |.   ..||.|....|.||.|..  ||.| .... | .  
dskadplfrvtklklvGgddeelfleh-wqgdvnylsdvysp---lrvlrklrnlskpvvvqdilGvskaatlvaieiallsllrGpit

Phosphatase R06B10.1.AA Subfamily.N_Choan_2.PD 960-1128 20 4.7e-17 53.0 In-house 75-246 (266) Show / Hide
Range on Protein: 960-1128
Range on HMM: 75-246/266
Sequence Identity: 20% (38 aa)

NSTIEKFWWMAMQERSKSIvqlceNMepTHNLDWDTSEACAEYVPLAEGGEIKFDGGSVRCVQKSMEFDDEGEVRQLLVKFdDQPEFTIEHLWYRGWKDR
..|...|| | ..|....|      |  | .|  .  . |. | |   . ..|.  | .. .. | | ..   ...| ..  ... .. | ||  | |. 
pttlksfwrmiweekvtai-----vm--ttgleEkgrkkCerYWpaepkekvkladgkikvlalseekeegyiltrlrlek-kgetrrlvHfwyntWpdh

LVPESPK------IMLDLLDKVNTNT------TPVIVHCKNGISKSACFAYIELACQMIpgltSDQSDRDILYV---LLRMRAE
||...        .|..| .|.. .      .|..||| .|. .. ..  |. |....    . ..  |.| .   | . | . 
gvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtliaiDiavrlL----eetkkvdvlaiieelRkdRma

Phosphatase R06B10.1.AA Subfamily.R_Sponge_2.PD 944-1105 20 8.9e-17 52.4 In-house 67-220 (262) Show / Hide
Range on Protein: 944-1105
Range on HMM: 67-220/262
Sequence Identity: 20% (33 aa)

LRMILTQSPQHktktrnSTIEKFWWMAMQERSKSIVQLCENMEpthnldwDTSEACAEYVPLAEGGEIKFDGGSVRCVQKSMefDDEGEVRQLLVKFD--
| ||.| .      .|.| || | .  ....||.|..  |       .  | ||.| | ....| ..    |  .....  .|.| .. .  .. | .. 
kayiatqgPlk------etveDfWRmvweykvstivmltnlee-------ngkekcakYWPekvdeeveygkfkvtlkeeek--ladyiirklklskeks

DQPEFTIEHLWYRGWKDRLVPESPKIMLDLLDKV-----NTNTTPVIVHCKNGISKSACFAYIELACQM
.  .  | .  ||..  ..|.|...|     ... ....|.|..|....  |  ..   .         
segeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsdgvgrtGtfialdsvler

Phosphatase R06B10.1.AA Subfamily.RB.PD 910-1128 22 1.2e-16 51.9 In-house 34-238 (261) Show / Hide
Range on Protein: 910-1128
Range on HMM: 34-238/261
Sequence Identity: 22% (50 aa)

TVSMFANSQNALVGYGKRFVDGYIHASKVIFPNNL-RMILTQSPQHKtktrnsTIEKFWWMAMQERSKSIVQLCENMEPTHnldwdtsEACAEYVPLAEG
.  . .|.  |    ..  . || |. .   |.    | || | ..      |...|| | ....|. || | . .|  .       | ||| |  |   
nilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpe------tvddfWrmvwekkssiivmltqlvEkgk-------ekceeYWPadee

geiKFDGGSVRCVQKSMEFDDEGEVRQLLVKFDDQpEFTIEHLWYRGWKDRLVPESPKIMLDLLDKVNT------NTTPVIVHCKNGISKSACFAYIELA
 .   |...   .. .  ||  .|.. .. ... . ..... .  | |  |||..| .||.. .|..      ...|..||||. ..  |  ..   | |
---pvlyGdikvtllaekeldewvirefkiekgke-krkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHCsaGvGRtGtfialdrl

CQMIPGltsdQSDRDILYVLLRMRAE
      .   |.. |. ..| |    
lqaiee----ndyvdvfgvvaelRee

Phosphatase R06B10.1.AA Subfamily.R_Anemone_1.PD 932-1100 27 8.1e-16 49.5 In-house 55-211 (258) Show / Hide
Range on Protein: 932-1100
Range on HMM: 55-211/258
Sequence Identity: 27% (47 aa)

YIHASKVIF-PNNLRMILTQSPQhktktrNSTIEKFWWMAMQERSKSIVQLCenmepthNLDWDTSEACAEYVPLaegGEIKFDGGSVRCVQKsMEFDDe
|| || .    .    |.||.|       ..|.| || | .||.. .|| |        ||   . . | .| |    .. |..  .|.  .|  .| | 
Yinasylrasdktrafiatqapl------eetvedFWrmvwqekigviVmLt-------nliegekkkchqYwPd---stekygelrvslrkk-evfad-

GEVRQLLVKFDD-QPEFTIEHLWYRGWKDRLVPESPKIMLDLLDKVNT----NTTPVIVHCKNGISKSACFAYIE
  .|.|... .. . | .. .. .  | |. ||.  . .|.|..||..    ...||.||| .|...  |  |. 
yiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqksslagarpvvvhCsaGvgRtGaflvid

Phosphatase R06B10.1.AA Subfamily.N_Choan_1.PD 931-1127 21 1.3e-15 48.5 In-house 55-238 (262) Show / Hide
Range on Protein: 931-1127
Range on HMM: 55-238/262
Sequence Identity: 21% (43 aa)

GYIHASKVI-FPNNLRMILTQSPQHktktrnSTIEKFWWMAMQERSKSIVQLCENMEPTHnLdwdtseACAEYVPlAEGGEIKFdgGSVRCVQKSMEFDD
|| |. |  . .. . | ||.|        .....||.| .... . || . ...|  . |       |  | |  |  |.|.| |.  ..| |   .  
DyinanfvpgykgekeyiatqgPvP------aslvsfWqmvweqkvsaivmvtreieagk-l------kChryWP-denselkl--gdvtvkslseeekk

EGEVRQLLVKFDDQPEFTIEHLWYRGWKDRLVPESPKIMLDLLDKV----NTN-TTPVIVHCKNGISKSACFAYIELACQMIPgltSDQSDRDILYVLLR
 |.. .. ..  . ..|.| |  | |. ||...| .|.  ..|    ...  .|...||  |. ....  .. ... .    ....  |.  |.  .|  
tyierkfkleresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktkaplvihCsaGvGrtGtyialDrlvkave---ekaealdvkavvae

MRA
   
lrk

Phosphatase R06B10.1.AA PTPc_motif 1047-1145 20 2e-15 58.5 SMART 1-92 (92) Show / Hide
Range on Protein: 1047-1145
Range on HMM: 1-92/92
Sequence Identity: 20% (21 aa)

TIEHLWYRGWKDR-----LVPESPKIMLDLLDKVNTNTTPVIVHCKNGISKSACFAYIELACQMIPGLTSDQSDRDILYVLLRMRAECFPNYQLYSFALY
|. |..| .|.|       |||  . .|.....|.    |..||| .|.. ...|. |....|.        .  ...  .  .|.  . ... | |  .
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK---PIVVHCSAGCGRTGTFCAIDMMMQQ-------VDIFQTVKEMRKQRPGMVQTEEQYIFCYR

GVFM
 .  
CILE

Phosphatase R06B10.1.AA Subfamily.R_Ecdysozoa.PD 931-1104 24 3.9e-15 46.8 In-house 56-226 (269) Show / Hide
Range on Protein: 931-1104
Range on HMM: 56-226/269
Sequence Identity: 24% (46 aa)

GYIHASKVI-FPNNLRMILTQSPQhktktrNSTIEKFWWMAMQERSKSIVQLCENMepthnldwDTSEACAEYVPLAegGEIKFDGGSVRCVQKSMEfdD
|| || .. . .. . |  |.|       ..||. || | ..  .. || | .          .....|| | |     |....   |..|....   ..
dyinasfikgykekkkfiaaqdPv------eatigDfWrmiaeqevtlivmlsnlt--------eknrkcakyWpie--devqygdilvklvseekh--s

EGEVRQLLVKFDD----QPEFTIEHLWYRGWK-DRLVPESPKIMLDLLDKV----NTN-----TTPVIVHCKNGISKSACFAYIELACQ
   |.| |   .    . .  .    | ||| |  |||... .|.|...|    ..|      .|..|||..| ..|. |  ..|  | 
dyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgsrsPivvhCsaGvgrsgifvaldlllq

Phosphatase R06B10.1.AA Subfamily.RK.PD 946-1106 24 5.3e-15 46.3 In-house 73-226 (267) Show / Hide
Range on Protein: 946-1106
Range on HMM: 73-226/267
Sequence Identity: 24% (42 aa)

MILTQSPQHktktrnSTIEKFWWMAMQERSKSIVQLCenmepthNLDWDTS-EACAEYVPlaEGGEIKFDGGSVRCVQKSMefDDEGEVRQLLVKF---D
| || | .      .|.. || .  .|.. ||| |        .|| ...   | .| |  | .|....   | .|. ..  | .  || .|.      .
fivtqgPlq------etvkdfWrlvydencasivmlt-------eldvevgrvkClkyWP--edtevrygdikvelveael--dadlvvrifrveklarg

DQPEFTIEHLWYRGWKDR-LVPESPKIMLDLLDKVNTNTTP-----VIVHCKNGISKSACFAYIELACQMI
   ..... . || .   ||.| . .|.|. .|.. . .     ..||| .|  .| .|  |.  ..||  
qeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeeeeeGrivvhClaGaGrsGtfiaidivlemi

Phosphatase R06B10.1.AA Subfamily.RA.PD 946-1105 25 6.2e-14 43.0 In-house 72-224 (266) Show / Hide
Range on Protein: 946-1105
Range on HMM: 72-224/266
Sequence Identity: 25% (43 aa)

MILTQSPQhktktrNSTIEKFWWMAMQERSKSIVQLCENMEpthnldwDTSEACAEYVPlaEGGEIKFdgGSVRCVQKSMEFDDEGEVRQLLVK-----F
.| .| |.      . |.| || |  . .|..|| | |  |          | ||.| |  . | . .  | .|   | ..   .  ||..||.      
fiaaqGpk------eetvedfwrmiweqksativmltelke-------rkeekcaqywp--deGlvty--Geirvevkdetvledytvrdflvtqlpdat

DDQPEFTIEHLWYRGWKDRLVPESPKIMLDLLDKVNTN-----TTPVIVHCKNGISKSACFAYIELACQM
.....  .. . ...| .  || ..| ||.|| ||..        |..|||  |. ..  |  ..   ..
rekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanhpivvhcsaGvGrtGtfivldavler

Phosphatase R06B10.1.AA Subfamily.RN.PD 925-1105 26 6.3e-13 39.6 In-house 50-221 (264) Show / Hide
Range on Protein: 925-1105
Range on HMM: 50-221/264
Sequence Identity: 26% (49 aa)

GKRFVDGYIHASKVI--FPNNLRMILTQSPQhktktrNSTIEKFWWMAMQERSKSIVQLCENMEpthnldwDTSEACAEYVPlAEGGEIkFDGGSVRCVQ
..  . || || ..   | .   | ||.|       .||| .|| |  .. .  ||.|..  |       .  ..|..| |  || |. ..|. | . . 
asaeksdyinasaildhdprapayiatqgpl------sstiadfwqmvweqGvvvivnltrlee-------egvkqckrywp-deGsev-yhiyevhlvs

KSMEFDDEgEVRQLLVK-FDDQPEFTIEHLWYRGWKDRLVPESPKIMLDLLDKVNT----NTTPVIVHCKNGISKSACFAYIELACQM
 ||   || . .| .. .   |.  . .  |... || |.| .|..  |||      ..|..||| .|  .. ..  |.|..      
ehiwcddy-lvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlvler

Phosphatase R06B10.1.AA Subfamily.N13.PD 931-1126 23 1.6e-12 38.5 In-house 50-234 (259) Show / Hide
Range on Protein: 931-1126
Range on HMM: 50-234/259
Sequence Identity: 23% (47 aa)

GYIHASKVIFP---NNLRMILTQSPQHKtktrnsTIEKFWWMAMQERSKSIVQLCENMEPTHNldwdtseACAEYVPLAEGGEIKFDGgSVRCVQKSMEF
||| || .  |   .. ..|..| |  .      |.. || |  . ... |. .  . |  .         |  | |  .. ..|  .  ..  .  .. 
gyinaslikvpvgedeyeyiacqGPlPe------tvkdfwqmvweqkaeviamvtlekekgkv-------kchrywPerknkklkvsn-rlevellkvqk

DDEGEVRQLLVKFDDQPE-FTIEHLWYRGWKDRLVPESPKIMLDLLDKV---NTNTTPVIVHCKNGISKSACFAYIELAcqmiPGLTSDQSDRDILYVLL
 |.  ||.| ||  .  |   . || .  | |  || |.. .. .. .|   .|...|..|||  || .|  .  |. .|| . . . |.  .. ..|  
ldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqtdagPivvhcsaGiGrsGvlitidvv----lglierdkefdvkeivr

RMR
   
klr

Phosphatase R06B10.1.AA Subfamily.RG.PD 932-1100 23 3.8e-11 33.9 In-house 57-217 (264) Show / Hide
Range on Protein: 932-1100
Range on HMM: 57-217/264
Sequence Identity: 23% (41 aa)

YIHASKVI-FPNNLRMILTQSPQHktktrnSTIEKFWWMAMQERSKSIVQLCenmepthNLDWDTSEACAEYVPLAeGGEIKFDGGSVRCVQKSMEfdDE
|| || .  .  .   | || | .      .||| || |  ..... || |        .||  . . .. | |    . ....  .|. ..|.    ..
YinAsyidGyrrskeyivtqgplk------etiedFWrmiWehnaqiivmlt-------dldekgrrdedvyWPkk-deplelealkvtllskekl--sk

GEVRQLLVK---FDDQPEFTIEHLWYRGWKDRLVPESPKIMLDLLDK---VNTN-TTPVIVHCKNGISKSACFAYIE
  ||....|   .|.. | ..... |  | |  .|||   .|    |   .|.. . |..||...| .... .  ..
ytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaankeeaGPivvhdsaGvgragtyiald

Phosphatase R06B10.1.AA Subfamily.RC.PD 932-1110 23 6.3e-11 33.0 In-house 75-248 (288) Show / Hide
Range on Protein: 932-1110
Range on HMM: 75-248/288
Sequence Identity: 23% (44 aa)

YIHASKVI-FPNNLRMILTQSPqhktktRNSTIEKFWWMAMQERSKSIVQLCENMEpthnldwDTSEACAEYVplaEGGEIKFDGGSVRCvqKSMEFDDE
|| || .  . .  ..| .| |      .. |.. || | .... | || | |  |          | ||||    | |.  .    ||  .   .  .|
yinasfidsykkpekyiaaqGp------lketvddfwrmiferkvkvivmltelke-------Gdrekcaeyw---eeGkrayGdvevdl--kdtdkssd

GEVRQLLV-KFDDQPEFTIEHLWYRGWKDRLVPESPKIMLDLL----------DKVNT----NTTPVIVHCKNGISKSACFAYIElacQMIPGLT
.| . .  ..   .. .. |  | .. .|| || .|.|.           ....     .||..|||..|  ..  |  ..   ... .|     
yilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiall---allesle

Phosphatase R06B10.1.AA Subfamily.N14.PD 929-1102 26 6.9e-11 32.9 In-house 52-230 (275) Show / Hide
Range on Protein: 929-1102
Range on HMM: 52-230/275
Sequence Identity: 26% (49 aa)

VDGYIHASKVIFP---NNLRMILTQSPQHKtktrnsTIEKFWWMAMQERSKSIVQLCENMEpthnldwDTSEACAEYVPLAEGGEIKFDGGSVRCVQKSM
.||| ||..  .   ...  | .|.|...      |...|| |  ..  . ||.| |. |       |  | . .|.|  |  . . . |. ..|  |  
stgyinassikvsvggkersyivaqgPlel------tvqdfwqmvweqgvqlivmlteeee-------dgkeksfkylPkleskkktvefgkfkvttkfs

EFDDEGEVRQLLVKF-DDQPEFTIEHLWYRGWKDRLVPESPKIMLDLLDKVNT-------N-------TTPVIVHCKNGISKSACFAYIELA
|    ..| .|.   . | |. || |  | |. ||| .| .|. |..|..       .         ||.||| .|. ..      .|    
edsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvkeskPPvlvhCsaGvGrtGvlilsdll

Phosphatase R06B10.1.AA Subfamily.R_Anemone_2.PD 946-1104 25 1.2e-10 32.5 In-house 72-219 (262) Show / Hide
Range on Protein: 946-1104
Range on HMM: 72-219/262
Sequence Identity: 25% (42 aa)

MILTQSPQhktktrNSTIEKFWWMAMQERSKSIVQLCENMEPTHnldwdtsEACAEYVPlaEGGEIKFDGGSVRcVQKSMEFDDEgEVRQLLVKFDDQPE
| ||.|         ||| || |  .  |. ||.| . .| ..         .. | |  . | ....   |  .....|..|   .|.. ||  ...| 
yiatqaPl------petiedfWrmvWeqnsavivmltqeeergk-------akvhryWP--skgsrsygklvve-lkeevelsdy-vlrsfkvkrteeee

-FTIEHLWYRGWKDRLVPESPKIMLDLLDKVNTN-----TTPVIVHCKNGISKSACFAYIELACQ
 ..    |  | |. ||||.  .|||. .|..      ..|..|||  |. .   |  ..   . 
erqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpivvhcsaGvGrtGvfiavdille

Phosphatase R06B10.1.AA Subfamily.N9.PD 930-1099 26 3.4e-09 27.5 In-house 54-227 (275) Show / Hide
Range on Protein: 930-1099
Range on HMM: 54-227/275
Sequence Identity: 26% (48 aa)

DGYIHASKVI-FPNNLRMILTQSPQHKTktrnstIEKFWWMAMQERSKSIVQLCENMEPTHnldwdtsEACAEYVPLAEGGEIKFDGGSVRCVQKSMEfd
||.|. |  . ..  .|.|| | .||      .. || |  ...   ||     .|  .         |..| || |.  ..|   ||.|.. .|  .. 
sdyinanfvdGykqkkafiatqGplkkt------vsdfwrmvweqevlvivmttrvvergr-------lkcgqywpleeessaefgdlsvsnveveve--

DEGEVRQLLVK-FDDQPEFTIEHLWYRGWKDRLVPESPKIMLDLLDKVNTN-----------------TTPVIVHCKNGISKSACFAYI
.||.| .|  ... . .. |  . .| |  ||.| . .||.|.||  .                   |..|||  || ..|. .     
edykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdeskghlsgPPivvhcsaGiGrtGtfitl

Phosphatase R06B10.1.AA Subfamily.N_Nematode_eak.PD 926-1099 22 4.8e-08 23.6 In-house 49-206 (281) Show / Hide
Range on Protein: 926-1099
Range on HMM: 49-206/281
Sequence Identity: 22% (37 aa)

KRFVDGYIHASKVIFPNN-LRMILTQSPQhktktrNSTIEKFWWMAMQERSKSIVQLCENMEpthnldwDTSEACAEYVPLAEgGEIKFDGGSVRCVQKS
..  |||| || . |..   . |||  ..      .. .  || | ....| .|||| |..|          |    | |..|.    | . . ...  .
qlnrdGyinaslaefsevGrkyiltGias------edkvfafwqmvleqkspaivqlledve-------ekleksdkyfpdkt-evlkyGildverkeya

MEfDDEGEVRQLLVKFDDQpEFTIEHLWYRGWKDRLVPESPKIMlDLLDKVNTNTTPVIVHCKNGISKSACFAYI
  |.|.| ..  ..    . |  . || .  .|     .  | . .    .. ..|. . .|    ||       
vk-rniletrllilrkGne-thrvlhykvfGwtettlpkyedfl-alrkvmkevGvlllivmksallrstlkkyi

Sequence
Name Sequence Type Origin Length Description Download
R06B10.1.AA Protein None 1236 None Fasta, JSON
R06B10.1.NA RNA None 3708 None Fasta, JSON
R06B10.1.AA.PD_880-1149 Protein Phosphatase Domain None 270 None Fasta, JSON