• Phosphatome.Net

Gene C24F3.2

C24F3.2
Species: C.elegans
Alias: C24F3.2
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: DSP12
Protein domain

Protein domains of C24F3.2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase C24F3.2.AA Subfamily.DSP12.PD 1-145 43 1.5e-52 168.1 In-house 2-141 (143) Show / Hide 
Range on Protein: 1-145
Range on HMM: 2-141/143
Sequence Identity: 43% (63 aa)

MWKITENLYLAQLPMIVGPTSKQEFsknDIKRVLTLTTEPISEKQKIGGVDYKFLHLLDMPDEPILDNaiLETAVLYINEGVEKEENVGVHCLAAVSRSV
...|...|||..|.... .....|.   .|..||....|...|.||. ||..|....||.|.|..|..  |..|| .|.||.|||..| |||||.|||||
vseilpglylggleavqerellkel---kithvlsvikeelpelqkekgvkskliqilDepeedlLsh--ldeavrFieeglekegavlvHClagvSRSv

SICAAYLMYKNQWPVEKALKMIESVRKTIGPNAGFLAQLKIWERS
.|..||||.|.....|||||......|.| ||.|||.|||..|..
tiviAYlmkkeklslekAlklvkekkkeiepNegFleQLklfekm
Phosphatase C24F3.2.AA Family.DSP.PD 3-154 28 1.5e-28 90.8 In-house 109-255 (387) Show / Hide 
Range on Protein: 3-154
Range on HMM: 109-255/387
Sequence Identity: 28% (44 aa)

KITENLYLAQLPMIvgpTSKQEFSKNDIKRVLTLTTEPISeKQKIGGVDYKFLHLLDMPDEPILDNaiLETAVLYINEGVEKEENVGVHCLAAVSRSVSI
.|...|||..|      ......... ..... ||... .  .| .|. |  ... | . .|.     .| |. .|.|| .....| ||| | ..|| ..
eilphlylgsllaa---knlewlkelgvtkivnltddkpq-ftkelgikylripidDhnapplenl--fekaidfieegndskgvVlVHCkaGkgRsgtl

CAAYLMYKNQWPVEKALKMIESVRK-TIGPNAGFLAQLKIWERSGMSFSADQY
..||||.....  |.||... |.|.  | || |||.||| .| . .. |  . 
iiaYlmksegltleealdwvrskRpgvitpnqgflkqlkdlekeklkvssevm
Phosphatase C24F3.2.AA Subfamily.DSP19.PD 3-143 32 8.6e-26 81.1 In-house 4-137 (139) Show / Hide 
Range on Protein: 3-143
Range on HMM: 4-137/139
Sequence Identity: 32% (46 aa)

KITENLYLAQLPMIvgpTSKQEFSKNDIKRVLTLTTEPISEkqKIGGVDYKFLHLLDMPDEPILDNaiLETAVLYINEGVEKEENVGVHCLAAVSRSVSI
.....|||.        ..|....|..|  .| ....          . || ...|| |.. .|.   |..|. .|.|. .|.  | |||| ||||.|. 
evkprlylgsqdva---adkeilkklkitHilnvavgvpnv--fpkdftyksieilDlpetkllsy--lkealdFieearskdgrvlvHCnAGvSRsasv

CAAYLMYKNQWPVEKALKMIESVRKTIGPNAGFLAQLKIWE
 |||| ...  .||||... . |..| ||.||. ||| .| 
viaylmkdeelslekalekvrearpcikPneGFikqLkeye
Phosphatase C24F3.2.AA Subfamily.DSP6.PD 4-144 30 2.9e-23 72.7 In-house 5-140 (141) Show / Hide 
Range on Protein: 4-144
Range on HMM: 5-140/141
Sequence Identity: 30% (43 aa)

ITENLYLAQLPMivgPTSKQEFSKNDIKRVLTLTTEPISEKQKIGGVDYKFLHLLDMPDEPILdnAILETAVLYINEGVEKEENVGVHCLAAVSRSVSIC
|...||| .       .  . ..| .||.|| .|..  .  .. | . || . . |   . .   . .  |. .|.|. .|...| ||||||||||... 
ilpllylGsakd---asnlevlkklkikyvlnvtsnlpnkfeesgelkykqipiedhlsqnla--kffPeaiefidearskkskvlvhclaGvsrsvtvt

AAYLMYKNQWPVEKALKMIESVRKTIGPNAGFLAQLKIWER
|||| |..  ...| ..... .  | ||  |. ||. .|| 
laylmkklalslndaydlvkkkksnisPnfnfmgqlldfer
Phosphatase C24F3.2.AA DSPc 1-145 24 1.5e-22 82.16 SMART 2-172 (172) Show / Hide 
Range on Protein: 1-145
Range on HMM: 2-172/172
Sequence Identity: 24% (42 aa)

MWKITENLYLAQLPMIVGPTSKQEFSKNDIKRVLTLTTE-PI-SEKQKI-------------GGVDYKFLH-LLD-------MPDEPILDNAILETAVLY
. .||..|||.  | .. | .. ...|..|. |. .| | |. ... ..             ..  |. .  . |       .. ..|.  . .. .. .
PSEITPHLYLGSYPHHMEP-NPCFLKKHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNIS--QYFPEVYDF

INEGVEKEENVGVHCLAAVSRSVSICAAYLMYKNQWPVEKALKMI-----ESVR-KTIGPNAGFLAQLKIWERS
|..   |  .| |||.| .|||...|.||||........ |. ..      ..|   | ||..|..||. ||| 
IHDCRQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK
Phosphatase C24F3.2.AA DSPc 83-145 34 4.5e-22 78.68 Pfam 83-151 (151) Show / Hide 
Range on Protein: 83-145
Range on HMM: 83-151/151
Sequence Identity: 34% (24 aa)

EKEENVGVHCLAAVSRSVSICAAYLMYKNQWPVEKALKMI-----ESVR-KTIGPNAGFLAQLKIWERS
.| ..| |||.| .|||...|.||||........ |. ..     ...|   |.||..|..||  .|| 
QKGGKVLVHCQAGISRSACLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ
Phosphatase C24F3.2.AA Subfamily.DSP15.PD 3-143 27 9.4e-22 68.1 In-house 4-136 (138) Show / Hide 
Range on Protein: 3-143
Range on HMM: 4-136/138
Sequence Identity: 27% (39 aa)

KITENLYLAQlpmIVGPTSKQEFSKNDIKRVLTLTTEPiseKQKIGGVDYKFLHLLDMPDEPILDnaILETAVLYINEGVEKEENVGVHCLAAVSRSVSI
|. . ||. .   . .   |. ...|.|  .|..  ..   |. . .. |. ..  | || ..     .. .. .| .   ...|| ||||| .||||..
kvlpGlyvGn---frdakdkeqleenkithilsihdsa---kplledikylcikaadsPdqdlsk--ffkesidfihkcrleggnvlvhclaGisrsvtl

CAAYLMYKNQWPVEKALKMIESVRKTIGPNAGFLAQLKIWE
..||.|   ..  |.|||.... |   .||.||  ||. .|
vvayimtvtelswedalkavkaarsvanPnvGfrrqlqefe
Phosphatase C24F3.2.AA Subfamily.DSP14.PD 2-144 31 1.2e-20 64.6 In-house 3-137 (138) Show / Hide 
Range on Protein: 2-144
Range on HMM: 3-137/138
Sequence Identity: 31% (44 aa)

WKITENLYLAqlpmIVGPTSKQEFSKNDIKRVLTLTTEPIseKQKIGGVDYKFLHLLDMPDEPIldNAILETAVLYINEGVEKEENVGVHCLAAVSRSVS
.|||.|||.     .. ..|....|. |  .. .|||    ..|. .|..  ... |.|.. .  .. .....  |.|  .|. .. |||| |||| |..
seitesLyls----gaaalkkeklkkkkitlivnvttelp--etkledvktvkikveDkpeakl--aehfdevadkieevkkkgGktlvhCvaGvsRsAs

ICAAYLMYKNQWPVEKALKMIESVRKTIGPNAGFLAQLKIWER
 ||||  ..  ...| |...| |  | || ||  ||  .|.  
lvlaylmkyeklsLreayklvksaRpiirPnvGFwkqlidyEk
Phosphatase C24F3.2.AA Subfamily.DSP1.PD 20-144 28 1.4e-20 64.4 In-house 18-138 (139) Show / Hide 
Range on Protein: 20-144
Range on HMM: 18-138/139
Sequence Identity: 28% (36 aa)

TSKQEFSKNDIKRVLTLTTEpISEKQKiGGVDYKFLHLLDMPDEPILdnAILETAVLYINEGVEKEENVGVHCLAAVSRSVSICAAYLMYKNQWPVEKAL
...| ... .|  .| ...| .... .     || ... | ... |.  . .|.|. .|..  .|.  | ||| | .||| .|. |||| .... .|.| 
snlqlLkelkitallnvsae-lpnvfe-elfkyksipvednkkadis--slfeeaidfidsvkkkgGrvlvhCqaGisrsativlayLmkekkvrleeaf

KMIESVRKTIGPNAGFLAQLKIWER
. . . |. | || ||. ||  .|.
efvkqrrsiisPnfgfvgqLlefek
Phosphatase C24F3.2.AA Subfamily.DSP10.PD 21-144 30 8.8e-20 61.7 In-house 19-140 (141) Show / Hide 
Range on Protein: 21-144
Range on HMM: 19-140/141
Sequence Identity: 30% (37 aa)

SKQEFSKNDIKRVLTLTTEPISEKQKIGGVDYKFLHLLDMPDEPIldNAILETAVLYINEGVEKEENVGVHCLAAVSRSVSICAAYLMYKNQWPVEKALK
.|. ... .|| || .||.   . .. | | || . . | . . .  .  .| |. .|.|  .....| ||| | .|||. .  ||.|.  ...| |.. 
dkdaldrlgikyvlnvttsvPnffeekglvrykripvsdsgkqnl--kqkfeealefieearkrgsrvlvhchaGisrsatvviayvmkhlslslseayk

MIESVRKTIGPNAGFLAQLKIWER
. | .| || .|. ||  .|.   
fvkekrPiisPnlnfmGqllefek
Phosphatase C24F3.2.AA Subfamily.Slingshot.PD 21-143 31 2.4e-19 60.2 In-house 19-137 (139) Show / Hide 
Range on Protein: 21-143
Range on HMM: 19-137/139
Sequence Identity: 31% (38 aa)

SKQEFSKNDIKRVLTLTTEpIsEKQKIGGVDYKFLHLLDMPDEPILDNaiLETAVLYINEGVEKEENVGVHCLAAVSRSVSICAAYLMYKNQWPVEKALK
.|...|... .| .|.| | ..   . ..|. ... | ... .|..   ...  .|..  ||. .| |||   |||| |.  ||| . .. .|.||. ..
nleelkengveyilnvtke-i-dnffpekfkylnirvydeeetdllkh--wnetykfiekakekgskvlvhckmGvsrsastviayamkeyelsleeale

MIESVRKTIGPNAGFLAQLKIWE
. |. | ||.||| |||..|   
yvkerrsiikpnkgflkqlkvye
Phosphatase C24F3.2.AA Subfamily.DSP8.PD 3-145 26 1.6e-17 54.5 In-house 4-141 (143) Show / Hide 
Range on Protein: 3-145
Range on HMM: 4-141/143
Sequence Identity: 26% (37 aa)

KITENLYLAQLpmiVGPTSKQEFSKNDIKRVLTLTTEPISEKQKIGGVDYKFLHLLDMPDEPILDnaILETAVLYINEGVEKEENVGVHCLAAVSRSVSI
.|..||||      . . ... ..|..|  || ....   . . .  . .  . . |  .| .|.  ....|. .|.  .... .| |||||||| ..  
rilpnlylGsq---kdsldeellkklgisyvlnisescpkdvellkesrflriPvkDkyeekllp--wfdkalefidkarsangkvlvhclaGisrsatv

CAAYLMYKNQWPVEKALKMIESVRKTIGPNAGFLAQLKIWERS
||.| . .  ...| . . . |.|| ||  || ||  .|..  
aiayimktlemsldeayrfvkekrptispnlnflgqLleyeke
Phosphatase C24F3.2.AA Subfamily.PTPMT1.PD 4-132 30 4.7e-17 52.8 In-house 2-133 (146) Show / Hide 
Range on Protein: 4-132
Range on HMM: 2-133/146
Sequence Identity: 30% (41 aa)

ITENLYLAQLPMivGPTSKQEFSKNDIKRVLTLTTE-------PISEKQKIGGVDYKFLHLLDMPDEPILDNaiLETAVLYINEGVEKEENVGVHCLAAV
| |...|  ||.    . |. . |...| |..|. |       . .|. |  ||..  |   |. . | |..  || .| .|..  .|...| ||| |  
idetvilGalPf--rsltkeLvekenvkavvslneeyelkalansteewkklGveqlqlatvDfteapslek--leegvefiekvaskgssvYvHCkAGr

SRSVSICAAYLMYKNQWPVEKALKMIESVRKTIGPN
.|| .. |.|||.|...  |.| |.... |..|  .
tRsatlvacylmkkkklspeeavkflkkkRpqirlk
Phosphatase C24F3.2.AA Subfamily.LRR-DSP.PD 52-144 38 1.1e-16 51.5 In-house 47-136 (137) Show / Hide 
Range on Protein: 52-144
Range on HMM: 47-136/137
Sequence Identity: 38% (35 aa)

YKFLHLLDMPDEPILDnaILETAVLYINEGVEKeENVGVHCLAAVSRSVSICAAYLMYKNQWPVEKALKMIESVRKTIGPNAGFLAQLKIWER
|  ... |...  | .   ..    .|.|| ||   | .|| | |||| ..  |||| ||.   ..|| .. . |  | || ||| |||.|. 
yliidiedvdeadiyq--hfkemnafidegrek-ggvlihcragvsrsatlviaylmkknslkfkealdlvikkrpriypnrgfldqlkkfek
Phosphatase C24F3.2.AA Subfamily.DSP3.PD 49-140 31 3.5e-16 50.1 In-house 54-143 (148) Show / Hide 
Range on Protein: 49-140
Range on HMM: 54-143/148
Sequence Identity: 31% (29 aa)

GVDYKFLHLLDMPDEPIldNAILETAVLYINEGVEK-EENVGVHCLAAVSRSVSICAAYLMYKNQWPVEKALKMIESVRkTIGPNAGFLAQLK
.. |  ..  |.|.  .  ..  |.|. .|.| ... .  | ||| . .|||  .  |||| ...  ...|.|.. . | .|.|| |||.|| 
eikylGvevsDvpefdl--skyfeeaadfidealsqkngkvlvhcvvGisRsatlvlayLmirrkltlkeaiktvrkkr-eilPneGflkqLl
Phosphatase C24F3.2.AA Subfamily.STYXL1.PD 56-144 29 4.1e-16 50.1 In-house 56-142 (143) Show / Hide 
Range on Protein: 56-144
Range on HMM: 56-142/143
Sequence Identity: 29% (26 aa)

HLLDMPDEPILDNaiLETAVLYINEGVEKEENVGVHCLAAVSRSVSICAAYLMYKNQWPVEKALKMIESVRKTIGPNAGFLAQLKIWER
.. | ..  .|..  |. .| .|.. ....| | |     .|||... .|||||....  .||.| ..  .. . || .|. ||. ||.
avedeneadller--lkevvqfiekhkkegevvlvfsnkGisrsaaviiaylmyskkitlkkaykylkkckenvkPnrafveqlseWek
Phosphatase C24F3.2.AA Subfamily.STYX.PD 55-143 32 1e-10 32.3 In-house 54-144 (146) Show / Hide 
Range on Protein: 55-143
Range on HMM: 54-144/146
Sequence Identity: 32% (30 aa)

LH-LLDMPDEPIlDNAI--LETAVLYINEGVEKEENVGVHCLAAVSRSVSICAAYLMYKNQWPVEKALKMIESVRKTIGPNAGFLAQLKIWE
.. .||. |... .| |  | |.  .|.. ..|  .| ||  | .||| ..  ||.|        .| ....  |  | ||.||  ||| .|
rylvldvadntv-eniirylptvkefiddslqkggkvlvhgnagisrsaalviayimetyglkyreafayvqerrfcinpnegfvsqlkeye
Phosphatase C24F3.2.AA Subfamily.DSP23.PD 25-127 25 2.8e-10 31.0 In-house 9-108 (128) Show / Hide 
Range on Protein: 25-127
Range on HMM: 9-108/128
Sequence Identity: 25% (25 aa)

FSKNDIKRVLTLTTEPISEKQKIGGVDYKFLHLLDMPdEPILDNaiLETAVLYINEGVEKEENVGVHCLAAVSRSVSICAAYLMYKNQWPVEKALKMIES
.  . |. ...||||. ....   .. .. ... |    | |.   ..  |  ..|  .||| |||||.  . |. .. | ||. .....|.  .   ||
ladqGirvlvslttegapyseaapsltlrridipdfc-PPaleq--varlvriveeaekkeeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrk

VRK
   
rrk
Phosphatase C24F3.2.AA Subfamily.Laforin.PD 38-127 29 7.8e-10 29.3 In-house 59-146 (165) Show / Hide 
Range on Protein: 38-127
Range on HMM: 59-146/165
Sequence Identity: 29% (26 aa)

TEPISEKQKIGGVDYKFLHLLDMPDEPILDNaiLETAVLYINEGVEKEENVGVHCLAAVSRSVSICAAYLMYKNQWPVEKALKMIESVRK
. .    |  |. | .| . |.  |  ..|  |  ||  .   .||   | ||| | | || .|   .|.|  .| . |   .. . |  
pitlkklykeeglayiwlptedlstesrven--lpqavyllhallekghivyvhcnagvgrstaivcgflqyvlgwslakvqyfllakrp
Phosphatase C24F3.2.AA Subfamily.PTPDC1.PD 81-126 33 4.1e-08 23.6 In-house 163-207 (229) Show / Hide 
Range on Protein: 81-126
Range on HMM: 163-207/229
Sequence Identity: 33% (15 aa)

GVeKEENVGVHCLAAVSRSVSICAAYLMYKNQWPVEKALKMIESVR
. .| ...||| |   |  .. |.||.|...   |.|.|.. | | 
al-eegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskr
Phosphatase C24F3.2.AA Subfamily.DSP11.PD 76-126 24 1.5e-06 18.7 In-house 72-122 (141) Show / Hide 
Range on Protein: 76-126
Range on HMM: 72-122/141
Sequence Identity: 24% (12 aa)

LYINEGVEKEENVGVHCLAAVSRSVSICAAYLMYKNQWPVEKALKMIESVR
....  .... .||||   | |.  .   ||. .. .  |.|... |..| 
efleknkdndkligvhCthGvnrtGyliCrylidvegyspedaieafeear
Phosphatase C24F3.2.AA Subfamily.RNGTT.PD 85-127 34 1.7e-06 18.4 In-house 79-121 (140) Show / Hide 
Range on Protein: 85-127
Range on HMM: 79-121/140
Sequence Identity: 34% (15 aa)

EENVGVHCLAAVSRSVSICAAYLMYKNQWPVEKALKMIESVRK
.| .||||     |   . .|||. | .| ||.|...  . |.
devigvhCthGfnrtGflivayLvekedwsveaavalfakarp
Phosphatase C24F3.2.AA Subfamily.CDC14.PD 23-136 23 2.1e-06 18.2 In-house 141-251 (258) Show / Hide 
Range on Protein: 23-136
Range on HMM: 141-251/258
Sequence Identity: 23% (27 aa)

QEFSKNDIKRVLTLTTEpISEKQKIGGVDYKFLHLLdMPDEPILDNAILETaVLYINEGVekEENVGVHCLAAVSRSVSICAAYLMYKNQWPVEKALKMI
. | ||... .. |  . . ...|     .. | |.   |  . ..|||.   | | | .  | .. ||| | . |  .. ..||... .. ..  .  .
eyfrknnvttivrLnkk-lYdakkftdaGfahlDlf-fiDGtvPsdailkk-fleiteka--eGaiavhCkaGLGrtgtligcylikhyrftaaetiawl

ESVR--KTIGPNAGFL
|    |||   .|   
riarPGsvigpqqtyl
Sequence
Name Sequence Type Origin Length Description Download
C24F3.2.AA Protein None 272 None Fasta, JSON
C24F3.2.NA RNA None 816 None Fasta, JSON
C24F3.2.AA.PD_1-145 Protein Phosphatase Domain None 145 None Fasta, JSON