• Phosphatome.Net

Gene F26A3.4

F26A3.4
Species: C.elegans
Alias: F26A3.4
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: DSP14
Protein domain

Protein domains of F26A3.4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase F26A3.4.AA DSPc 13-151 30 1.8e-60 208.14 SMART 1-172 (172) Show / Hide 
Range on Protein: 13-151
Range on HMM: 1-172/172
Sequence Identity: 30% (53 aa)

AMSEIVPGLFICGVSALS---KDEMKKHKITHIINATTEVPN----------------LRSLGDIQRTKLW-LED-------TPQTYIYPHLELQSDQIQ
..||| |.|.... .. .   ....|||.|||.||.| |.|.                ... ...|.  .. ..|       ...|.|.....  .| |.
GPSEITPHLYLGSYPHHMEPNPCFLKKHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFIH

ALIADGGKVLVHCVAGVSRSASICLAFLLKYRCRNLREAYHLM-----KSKR-SMVRPNLGFWRQLIAYEQN
.....|||||||| ||.||||..| |.|.||.......|||..     |..| ....||..||.||...|. 
DCRQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK
Phosphatase F26A3.4.AA Subfamily.DSP14.PD 14-151 50 4.8e-59 189.0 In-house 2-138 (138) Show / Hide 
Range on Protein: 14-151
Range on HMM: 2-138/138
Sequence Identity: 50% (69 aa)

MSEIVPGLFICGVSALSKDEMKKHKITHIINATTEVPNLRsLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAFL
.||| . |...|..||.|...||.|||.|.|.|||.|. . | |....|...||.|.. ...|.. ..|.|... ..|||.|||||||||||||..||.|
lseitesLylsgaaalkkeklkkkkitlivnvttelpetk-ledvktvkikveDkpeaklaehfdevadkieevkkkgGktlvhCvaGvsRsAslvlayl

LKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQN
.||....|||||.|.||.|...||| |||.|||.||..
mkyeklsLreayklvksaRpiirPnvGFwkqlidyEkk
Phosphatase F26A3.4.AA DSPc 21-151 34 2.6e-57 201.21 Pfam 1-151 (151) Show / Hide 
Range on Protein: 21-151
Range on HMM: 1-151/151
Sequence Identity: 34% (52 aa)

LFICGVSALS--KDEMKKHKITHIINATTEVPN--LRSLGDIQRTKLW-LED---------TPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSA
|.... .. .  .. ..||.|||.||.|.|.||  ... ..... ... ..|         ...|.|..... ..|.|......|||||||| ||.||||
LYLGSYPHHMADPAFLQKHGITHVINCTMECPNNWFYHNSHFHYMWIPHVHDHIHYYHIHWNHCTNISQYFPMATDFIDDCRQKGGKVLVHCQAGISRSA

SICLAFLLKYRCRNLREAYHLM-----KSKR-SMVRPNLGFWRQLIAYEQN
..|.|.|.|||. ...|||...     |..| .|..|| .|||||..||..
CLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ
Phosphatase F26A3.4.AA Subfamily.DSP1.PD 15-150 35 3e-35 111.9 In-house 3-138 (139) Show / Hide 
Range on Protein: 15-150
Range on HMM: 3-138/139
Sequence Identity: 35% (49 aa)

SEIVPGLFICGVSALS-KDEMKKHKITHIINATTEVPNLRSlGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAFL
.||.. |.. . .  | .. .|..|||...| ..|.||       .  .. .||.... |. ..|   | |... . ||.||||| ||.||||.|.||.|
veildfLyLGsaehasnlqlLkelkitallnvsaelpnvfe-elfkyksipvednkkadisslfeeaidfidsvkkkgGrvlvhCqaGisrsativlayL

LKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQ
.| .  .|.||.. .|..||.. ||.|| .||. .|.
mkekkvrleeafefvkqrrsiisPnfgfvgqLlefek
Phosphatase F26A3.4.AA Subfamily.DSP19.PD 15-150 36 1.3e-34 109.6 In-house 3-138 (139) Show / Hide 
Range on Protein: 15-150
Range on HMM: 3-138/139
Sequence Identity: 36% (50 aa)

SEIVPGLFICGVSA-LSKDEMKKHKITHIINATTEVPNLrSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAFL
.|. | |..  ...  .|...||.|||||.| ...|||.    |.. ... . |.|.| .  .|.   | |.     .| ||||| ||||||||. .|.|
aevkprlylgsqdvaadkeilkklkitHilnvavgvpnv-fpkdftyksieilDlpetkllsylkealdFieearskdgrvlvHCnAGvSRsasvviayl

LKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQ
.| .  .|..|.. ....|  ..|| ||..|| .||.
mkdeelslekalekvrearpcikPneGFikqLkeyea
Phosphatase F26A3.4.AA Subfamily.DSP12.PD 14-150 35 3.6e-33 105.3 In-house 2-140 (143) Show / Hide 
Range on Protein: 14-150
Range on HMM: 2-140/143
Sequence Identity: 35% (49 aa)

MSEIVPGLFICGVSALS-KDEMKKHKITHIINATTEV-PNLRSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLA
.||| |||.. |..|.  ....|. ||||..  ..|  |.|.   . ..  . . |.|.. .  ||.   . |.  .. .|.||||| ||||||..|..|
vseilpglylggleavqerellkelkithvlsvikeelpelqkekgvkskliqilDepeedlLshldeavrFieeglekegavlvHClagvSRSvtiviA

FLLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQ
.|.|..  .|..|..|.|.|.. ..|| || .||  .|.
YlmkkeklslekAlklvkekkkeiepNegFleQLklfek
Phosphatase F26A3.4.AA Subfamily.DSP10.PD 14-151 32 1.2e-31 100.1 In-house 2-141 (141) Show / Hide 
Range on Protein: 14-151
Range on HMM: 2-141/141
Sequence Identity: 32% (45 aa)

MSEIVPGLFIC-GVSALSKDEMKKHKITHIINATTEVPNLRSLGD-IQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLA
.|.|.| |..  .  | .|| .... |....| ||.|||  .  . ..  .. ..|.... .  ..|   . |.     |..||||| ||.|||| . .|
assilpflllGnekdaadkdaldrlgikyvlnvttsvPnffeekglvrykripvsdsgkqnlkqkfeealefieearkrgsrvlvhchaGisrsatvvia

FLLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQN
...|.    |.|||...|.|| .. |||.|  ||. .|..
yvmkhlslslseaykfvkekrPiisPnlnfmGqllefeke
Phosphatase F26A3.4.AA Family.DSP.PD 13-156 30 1.3e-28 91.0 In-house 106-251 (387) Show / Hide 
Range on Protein: 13-156
Range on HMM: 106-251/387
Sequence Identity: 30% (43 aa)

AMSEIVPGLFICGVSAL-SKDEMKKHKITHIINATTEVPNLRSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLA
.||| |.|.. . .|  .....|....|.|.|.|.. |.  . ..|.  .. ..|.... .  ..|   | |.    ..|.||||| ||..||.... |.
kpseilphlylgsllaaknlewlkelgvtkivnltddkpqftkelgikylripidDhnapplenlfekaidfieegndskgvVlVHCkaGkgRsgtliia

FLLKYRCRNLREAYHLMKSKRS-MVRPNLGFWRQLIAYEQNVKENA
|.|..  .| ||.....|||. ...|| ||..|| ..|..  .   
YlmksegltleealdwvrskRpgvitpnqgflkqlkdlekeklkvs
Phosphatase F26A3.4.AA Subfamily.DSP15.PD 14-150 31 2.5e-28 89.4 In-house 2-137 (138) Show / Hide 
Range on Protein: 14-150
Range on HMM: 2-137/138
Sequence Identity: 31% (43 aa)

MSEIVPGLFICGVS-ALSKDEMKKHKITHIINATTEVPnlRSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAF
|....|||.. ..  |  |. ....|||||.    .    . | ||.   .  .|.|.. .  ...   | | .   .||.|||||.||.||| ... |.
mnkvlpGlyvGnfrdakdkeqleenkithilsihdsak--plledikylcikaadsPdqdlskffkesidfihkcrleggnvlvhclaGisrsvtlvvay

LLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQ
..     . ..| . .|. ||.  ||.|| |||  .|.
imtvtelswedalkavkaarsvanPnvGfrrqlqefek
Phosphatase F26A3.4.AA Subfamily.DSP8.PD 15-152 30 1e-27 87.5 In-house 3-142 (143) Show / Hide 
Range on Protein: 15-152
Range on HMM: 3-142/143
Sequence Identity: 30% (43 aa)

SEIVPGLFI-CGVSALSKDEMKKHKITHIINATTEVPN-LRSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAF
.|.| |.. . . .|... .||  |....|.... |  .  | . .  .. ..|. .  . |...   . |.   .  ||||||| || ||||.. .|..
trilpnlylGsqkdsldeellkklgisyvlnisescpkdvellkesrflriPvkDkyeekllpwfdkalefidkarsangkvlvhclaGisrsatvaiay

LLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQNV
.|.   .| |||. .|.||... ||| |  ||. ||... 
imktlemsldeayrfvkekrptispnlnflgqLleyekel
Phosphatase F26A3.4.AA Subfamily.DSP6.PD 16-150 33 1.8e-27 86.4 In-house 4-140 (141) Show / Hide 
Range on Protein: 16-150
Range on HMM: 4-140/141
Sequence Identity: 33% (46 aa)

EIVPGLFIC-GVSALSKDEMKKHKITHIINATTEVPNL-RSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAFL
||.| |..    .|   . .||.|| ...| |...||  .. |... ... .||. .. .  ..    . |.    .  |||||| ||||||...||.|.
eilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkykqipiedhlsqnlakffPeaiefidearskkskvlvhclaGvsrsvtvtlayl

LKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQ
|...  | .||.|.|.|.| . ||. |  ||. .|. 
mkklalslndaydlvkkkksnisPnfnfmgqlldfer
Phosphatase F26A3.4.AA Subfamily.Slingshot.PD 27-149 34 3.6e-27 85.5 In-house 16-137 (139) Show / Hide 
Range on Protein: 27-149
Range on HMM: 16-137/139
Sequence Identity: 34% (42 aa)

SALSKDEMKKHKITHIINATTEVPNLRSlGDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAFLLKYRCRNLREAYH
|   .|.|......|.| |.|. |  . .... ... . |...| ...| .   . |..  ..| ||||||  |||||||. .|..|    .| ||.. .
nasnleelkengveyilnvtkeidnffp-ekfkylnirvydeeetdllkhwnetykfiekakekgskvlvhckmGvsrsastviayamkeyelsleeale

LMKSKRSMVRPNLGFWRQLIAYE
|..||...|| ||..|| .||  
yvkerrsiikpnkgflkqlkvye
Phosphatase F26A3.4.AA Subfamily.DSP3.PD 14-150 31 7.5e-25 78.2 In-house 2-147 (148) Show / Hide 
Range on Protein: 14-150
Range on HMM: 2-147/148
Sequence Identity: 31% (47 aa)

MSEIVPGLFICGV-SALSKDEMKKHKITHIINATTEVP--------NLRSLGDIQRTKLWLEDTPQTYIYPHLELQSDQIQ-ALIADGGKVLVHCVAGVS
. |. |.... .  .|  |...||  |||..||. .          .  .  .|. . .  .|.|.. .  . |  .| |. ||  ..||||||||.|.|
vdevypkvyvgdeavakdkekLkklGithvLnaaegkrllkvdtdaefYkdleikylGvevsDvpefdlskyfeeaadfidealsqkngkvlvhcvvGis

RSASICLAFLLKYRCRNLREAYHLMKSKRsMVRPNLGFWRQLIAYEQ
||| . ||.|. .|  .|.|| . ...|| .. || || .||.....
RsatlvlayLmirrkltlkeaiktvrkkr-eilPneGflkqLlelde
Phosphatase F26A3.4.AA Subfamily.LRR-DSP.PD 15-150 32 1.8e-24 76.8 In-house 3-136 (137) Show / Hide 
Range on Protein: 15-150
Range on HMM: 3-136/137
Sequence Identity: 32% (45 aa)

SEIVPGLFICGV-SALSKDEMKKHKITHIINATTEVPNLRSLgdIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGkVLVHCVAGVSRSASICLAFL
..|...|.. .  ||  |  .|. ..|||.  .   |    |  ..   . .||.... || |..     |.    .|| ||.|| |||||||.. .|.|
dliidklylgcresamnksilkdnnvthilavadfkplypdl--fkyliidiedvdeadiyqhfkemnafidegrekgg-vlihcragvsrsatlviayl

LKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQ
.|..  ...||. |...||. ..|| ||  ||  .|.
mkknslkfkealdlvikkrpriypnrgfldqlkkfek
Phosphatase F26A3.4.AA Subfamily.STYX.PD 14-149 34 2e-21 67.0 In-house 2-144 (146) Show / Hide 
Range on Protein: 14-149
Range on HMM: 2-144/146
Sequence Identity: 34% (50 aa)

MSEIVPGLFICGVSALSKD---EMKKHKITHIIN------ATTEVPNLRSlgDIQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSR
| ||.||||.   ||  |     .|.| ||||.       |.   ||..   ...   | . |..   |  .|    . |.  .  |||||||  ||.||
mqeilpglflgpysaamksklevlkehgithivcirqnieanlikpnfpd--rfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisr

SASICLAFLLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYE
||.. .|....    . |||.. .. .|  . || || .||  ||
saalviayimetyglkyreafayvqerrfcinpnegfvsqlkeye
Phosphatase F26A3.4.AA Subfamily.STYXL1.PD 15-150 27 1.4e-16 51.7 In-house 3-142 (143) Show / Hide 
Range on Protein: 15-150
Range on HMM: 3-142/143
Sequence Identity: 27% (37 aa)

SEIVPGLFICGVS--ALSKDEMKKHKITHIINATTEVPNLRS-LGD-IQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICL
.|..|| .  |    | ..   |  |.   .| ...  .| . | |  .  .. .||.... . ..|.   . |.    .|  ||||.||||.. .|.|.
vevlPgklylGnykqaqnpaikkdlkvkahvnvssdaekliagladvakllhiavedeneadllerlkevvqfiekhkkegevvlvfsnkGisrsaavii

AFLLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQ
 ..  .|..||. .|  .. |.|| .|  ||  .|.    
aylmyskkitlkkaykylkkckenvkPnrafveqlseWek
Phosphatase F26A3.4.AA Subfamily.PTPMT1.PD 58-150 28 2.7e-13 40.6 In-house 53-145 (146) Show / Hide 
Range on Protein: 58-150
Range on HMM: 53-145/146
Sequence Identity: 28% (26 aa)

IQRTKLWLEDTPQTYIYPHLELQSDQIQALIADGGKVLVHCVAGVSRSASICLAFLLKYRCRNLREAYHLMKSKRSMVRPNLGFWRQLIAYEQ
..  .|   |  ..    .||   . |.  . .| .| ||| || .|||..  ..|.| .  .  || ...|.||. .| .   || |...  
veqlqlatvDfteapslekleegvefiekvaskgssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpqirlkskqwralqefke
Phosphatase F26A3.4.AA Subfamily.Laforin.PD 84-135 36 5.3e-08 23.3 In-house 97-148 (165) Show / Hide 
Range on Protein: 84-135
Range on HMM: 97-148/165
Sequence Identity: 36% (19 aa)

IQALIADGGKVLVHCVAGVSRSASICLAFLLKYRCRNLREAYHLMKSKRSMV
..||. .| .| ||| ||| ||..|   ||      .|.   . . .|| .|
lhallekghivyvhcnagvgrstaivcgflqyvlgwslakvqyfllakrpvv
Phosphatase F26A3.4.AA Subfamily.R_Nematode_3.PD 93-110 60 3e-06 17.4 In-house 200-217 (267) Show / Hide 
Range on Protein: 93-110
Range on HMM: 200-217/267
Sequence Identity: 60% (9 aa)

KVLVHCVAGVSRSASICL
|.|||..|.||||..   
pvvVHCsdGisRsatlaa
Phosphatase F26A3.4.AA Subfamily.PTPDC1.PD 89-133 35 1e-05 15.7 In-house 164-208 (229) Show / Hide 
Range on Protein: 89-133
Range on HMM: 164-208/229
Sequence Identity: 35% (15 aa)

ADGGKVLVHCVAGVSRSASICLAFLLKYRCRNLREAYHLMKSKRS
||. ||| ||  |  ..  ..|.  .  .  || .|..|||.   
leegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrp
Sequence
Name Sequence Type Origin Length Description Download
F26A3.4.AA Protein None 226 None Fasta, JSON
F26A3.4.NA RNA None 678 None Fasta, JSON
F26A3.4.AA.PD_13-151 Protein Phosphatase Domain None 139 None Fasta, JSON