K02D10.1
Species: C.elegans
Alias: K02D10.1
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: HAD
Family: NagD
Subfamily: PGP
Protein domain

Protein domains of K02D10.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase K02D10.1.AA Subfamily.PGP.PD 15-260 51 1.3e-107 346.9 In-house 1-243 (243) Show / Hide
Range on Protein: 15-260
Range on HMM: 1-243/243
Sequence Identity: 51% (127 aa)

YDTFLFDADGVLWTGDIPVPGAIEWINLLLEDpSKKVFVLTNNSTKTLEQYMKKIEKLGFGHLGRNNVISPAIVLADYLKSNADKFSGEYVYLIGTENLK
.||.|||.|||||.|. ..|||.|..| | .. .|||...||||||| |.|.||..||||..| .....|.|.|||||||....|.....|||||.|.||
fdtvlfDcdGVlWlgetaipgavevlnaLraa-gKkvlfvtNnstktreeylkkfkklgfkvlkkeeilssaavladylkqakakkekkkvyligeeglk

ATLENdGGVKCFGTGPDSIRDHTDGDFIHKVDMSIAPKAVVCSYDAHFSYPKIMKASNYLQDPSVEYLVTNQDYTFPgPVPGVVIPGSGATSAAVTAVTG
..||.  |....|.|||...|..|||...||... ...|||...|.||||.|..||.||||.|.|....||.|.|.| ..|.|||||.|...|||....|
eelee-lgieslgvgpdkledeldgdlaekvklekdvgaVvvgfdehfsyvklakAlnylqnpdvlfvatneDetlp-lnpevvipgtGslvaavetasg

RDPKVFGKPHKPMADFLLRRAHVDPKRTVMFGDRLDTDIMFGNANG
|.|.|.|||.|...|.||..|..||.||.|.||||||||.||...|
replvvGKPskllldallekakidpertlmvGDrldtDilfgkncG

Phosphatase K02D10.1.AA Family.NagD.PD 15-260 47 5.6e-99 318.8 In-house 1-239 (239) Show / Hide
Range on Protein: 15-260
Range on HMM: 1-239/239
Sequence Identity: 47% (117 aa)

YDTFLFDADGVLWTGDIPVPGAIEWINLLLEDpSKKVFVLTNNSTKTLEQYMKKIEKLGFGHlGRNNVISPAIVLADYLKSNADKFSGEYVYLIGTENLK
.||.|||.|||||.|. ..|||.|..| | .. .|||...||||||. |...||..||||..  .....|.|...|||||....|  ...|||||.|.||
idtvlfDcdGVLwlgekaipgavealnrLrqk-gkkvlfvTNnstksreellkklqklgfkv-seeeifssaaaaadylkkrkkkpfkkkvyligeeglk

ATLENdGGVKCFGTGPDSIRDHTDGDFihKVDMSIAPKAVVCSYDAHFSYPKIMKASNYLQDPSVEYLVTNQDYTFpgPVPGVVIPGSGATSAAVTAVTG
..||.  |....|||||...|..|||.  .||.. . .|||...|.||||.|..||..|||.|.|....||.|.|.  . |.|.|||.|...||....||
eelee-lgieslgtgpdkledeldgdl--evdlekdvgaVvvgadehfsyeklakAfryLqnpdvlfiatnedktl--kepevlipgaGsfvaaletatg

RDPKVFGKPHKPMADFLLRRAHVDPKRTVMFGDRLDTDIMFGNANG
|...|.|||.|.....||....|||.||||.||||.|||.|....|
realvvGKPskllfealleklgvdpertvmiGDrlntDilfaqkcG

Phosphatase K02D10.1.AA Group.HAD.PD 15-257 19 3.9e-28 87.0 In-house 1-187 (190) Show / Hide
Range on Protein: 15-257
Range on HMM: 1-187/190
Sequence Identity: 19% (47 aa)

YDTFLFDADGVLWtgdipVPGAIEWINLLLEDPSKKVFVLTnNSTKTLEQYMKKIEKLGFGHLGRNnvispaivladylksnadKFSGEYVYLIGTEnLK
.||...| |||||     ..|. |... |.   ....|. . |.||.  ...|. ..|||   . .                  ..  |..  .|. .. 
kdtlvlDldgvlw-----lhgspepleglrskgkvlifltn-natksrlyllkrlallgflveeve------------------phldeflervgel-ye

ATLENdGGVKCFgtgpdsirdhtdgdfihkvdmsIAPKAVVCSY-DAHFSYPKIMKASNYLQDPSVEYLVTNQDYTFPGPVPG-VVIPGSGATSAAVTAv
  .| ...                        |.... .. | .||| |...|..||..| .  |.|| | ..... .  |||.. .. ..|. .     
lvvft-agtrey----------------------adpvvgavdvgdeafsyrklrdacvylkgpgalllatnrdlgalvrdlekvviidnkpsvfafec-

tgrdpkvFGKPHKPMADFllrrAhVDPKRTVMFGDRLDTDIM---FGN
   . ... .. ||       |.......|...|....   ||.    
-------npenalmigdf----i-ddildaellglipdlenidvrfgk

Phosphatase K02D10.1.AA Hydrolase 15-259 12 2.2e-15 54.16 Pfam 1-167 (167) Show / Hide
Range on Protein: 15-259
Range on HMM: 1-167/167
Sequence Identity: 12% (32 aa)

YDTFLFDADGVLWTGDIPVPGAIEWINLLLEDPSKKVFVLTNNSTKTLEQYMKKIEKLGFGHLGRNNVISPAIVLADYLKSNADKFSGEYVYLIGTENLK
.....|| ||.|..|   ..   . .. ....  .           . ......|   |. .    ..|  . . ....                     
IKAVVFDKDGTLTDG--SEHPHAQAWVEAAREYGY-----------WPFEEVEYIWGRGI-G---DRIIDWWRATDEHI---------------------

ATLENDGGVKCFGTGPDSIRDHTDGDFIHKVDMSIAPKAVVCSYDAHFSYPKIMKASNYLQDP-SVEYLVTNQDYTFPGPVPGVVIPG-SGATSAAVTAV
                                     ... . .|    || ...| ..|..     ...|| .. .. .|    ..|   . .. ... 
-----------------------------------D-EYLGVIAD-DQPYPGAREALQALKRMGIKVAMITNDNR-NAQAVLE--HLGIA-YFDHIIDSD

TGRDPKVFGKPHKPMADFLLRRAHVDPKRT--VMFGDRLDTDIMFGNAN
      ..||||. |.  ...|. |.|...  .|.||.. .|.|.  |.
DVG---IVGKPHPEMYEKACQRLGVKPHECGCMMVGDGINDDPMLAQAG

Phosphatase K02D10.1.AA Subfamily.LHPP.PD 17-97 23 4.3e-11 30.8 In-house 3-81 (213) Show / Hide
Range on Protein: 17-97
Range on HMM: 3-81/213
Sequence Identity: 23% (19 aa)

TFLFDADGVLWTGDIPVPGAIEWINLLlEDPSKKVFVLTNNSTKTLEQYMKKIEKLGFgHLGRNNVISPAIVLADYLKSNA
..| |  |||.. . ..||..| .. |  . . || ..||.. .. .. ......||| .. ...|.... . ...||.. 
gvllDlsGvlyveeaaipgsveAlkrL-kqsglkvrfvtnttkeskrelverLqrlgf-kveeeevftslpaarqllkkek

Phosphatase K02D10.1.AA Subfamily.LHPP.PD 134-254 27 7.8e-11 30.0 In-house 89-207 (213) Show / Hide
Range on Protein: 134-254
Range on HMM: 89-207/213
Sequence Identity: 27% (33 aa)

RDHTDGDFiHKVDMSiAPKAVV-CSYDAHFSYPKIMKASNYLQDPSVEYLVTNQDYTFPGPVPGVVIpGSGATSAAVTAVTGRDPKVFGKPHKPMADFLL
.|..  || ...|..  |.|||    . .|.| .. || . | . . . |.. .   .   . |... . ||  .|.   |. . .| |||.|      |
eddaredF-egidtd-spnavviglapesfnyetlnkafrlllekkkkvLiaigkgkyykrkdglal-dvGafvkaLeyatdveaevvGkPsklfFesal

RRAHVDPKRTVMFGDRLDTDIM
.  .|||...|| || .  |. 
qelgvdpeeavmiGDDvkdDvg

Sequence
Name Sequence Type Origin Length Description Download
K02D10.1.AA Protein None 299 None Fasta, JSON
K02D10.1.NA RNA None 897 None Fasta, JSON
K02D10.1.AA.PD_15-271 Protein Phosphatase Domain None 257 None Fasta, JSON