• Phosphatome.Net

Gene Y40H4A.2

Y40H4A.2
Species: C.elegans
Alias: Y40H4A.2
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: PPP
Family: PPP
Subfamily: PPP_Nematode_2
Protein domain

Protein domains of Y40H4A.2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase Y40H4A.2.AA Family.PPP.PD 7-329 37 6.6e-100 324.6 In-house 34-341 (349) Show / Hide 
Range on Protein: 7-329
Range on HMM: 34-341/349
Sequence Identity: 37% (120 aa)

RVDQDEDSENDQERVAYLKAFISRLMTAPMKEKspaevdvTVSKEEIRIISNYAAASFGSFSTLMRVDEDclpVHIVGDLHGHFGDLRRIFGIHGAPGIS
........  ...   .. ....|. |  ..|       .....|.  . . |.  . . ..|..|...   . ..||.|| | || |.| |.|.|  . 
sievedsytgprlsfkltpdlvkelveafkekk-------qleakevlelleeakellkkepnlleveap---itvcGDihGqfdDLlrlfdinglppae

-HYVFLGDYVDRGRQGIETVMLLMAYHCLYPDHLFLCRGNHEDYNTTMTYGFFDECRMKYgKKGTLAWLHIINAFNHLPLAALILDKVLCMHGGISPHIQ
.|.||||||||| . .|...||.|...|||...|| |||||. . .. ||| .|.. || |||.  .  . ..|| ||||||| .|.||.|||.||....
nkylFlGDyVDRGkfsvEvilllfalkllypsrffllRGnhEsrsvnkvygfyeevksky-kkgeeiyelfqevFnwLPlaalidekilcvhGGlspelt

KLEDIDKIQRPTFIPSYGLACDLVWSDPEKtsNVGWSLSARGISFSFDDITIEKFCQDNGLDLIVRAHQISSEmirgGHKWHANGRMVTIFSAANYLS-M
|..|.||.||. .|. ||.|||.|||||.  . ||. ..||..| | .  .|||.. |.||||.|||..  |    | ...||...||||||.||.. ..
sldqirkierpleppkegllcdllWsdpee--qkgwkpnkRGvgfvFgpdavekflkknnldliiRahevvee----GyeffanrklvTifsapnYcgey

GNDSCVIRIDEQKTMQFCLLRPVKK
|  .|...|.. .... ...|.|. 
snkaavlkvdknlklsivqfkpskh
Phosphatase Y40H4A.2.AA Subfamily.PPP_Nematode_2.PD 48-328 73 1.6e-180 587.9 In-house 1-281 (281) Show / Hide 
Range on Protein: 48-328
Range on HMM: 1-281/281
Sequence Identity: 73% (206 aa)

VSKEEIRIISNYAAASFGSFSTLMRVDEDCLPVHIVGDLHGHFGDLRRIFGIHGAPGISHYVFLGDYVDRGRQGIETVMLLMAYHCLYPDHLFLCRGNHE
|||||||||||||...|..||.|.||||.||||..|.||||...||.|||.|..|||||.|.|||||||||||..|.|.||.||..||||||||.|||||
vskeeiriisnyakkaflefsallrvdeeclpvtvvadlhgqsidllriflineapgiskylflgdyvdrgrqsvevvllllaykhlypdhlfllrgnhe

DYNTTMTYGFFDECRMKYGKKGTLAWLHIINAFNHLPLAALILDKVLCMHGGISPHIQKLEDIDKIQRPTFIPSYGLACDLVWSDPEKTSNVGWSLSARG
|.|||.||||||||..||..||...||.||.|||||||||||||||||.|||||||..||||||||.||...|||||||||.|||||||..|||||||||
dvnttltygffdeclekyndkgekvwlmiidafnhlplaalildkvlcahggisphlekledidkierplvvpsyglacdllwsdpektervgwslsarg

ISFSFDDITIEKFCQDNGLDLIVRAHQISSEMIRGGHKWHANGRMVTIFSAANYLSMGNDSCVIRIDEQKTMQFCLLRPVK
||||||||..||||.||.|||.|||||.|.||||.|||..||||.|..|||.|||||.|||.|....|.||.||..|..||
isfsfddivvekfcadndldlvvrahqlskemirqghklrangrlvslfsalnylsmkndssvlkleevktlqfvklkqvk
Phosphatase Y40H4A.2.AA Group.PPP.PD 7-329 37 6.6e-100 324.6 In-house 34-341 (349) Show / Hide 
Range on Protein: 7-329
Range on HMM: 34-341/349
Sequence Identity: 37% (120 aa)

RVDQDEDSENDQERVAYLKAFISRLMTAPMKEKspaevdvTVSKEEIRIISNYAAASFGSFSTLMRVDEDclpVHIVGDLHGHFGDLRRIFGIHGAPGIS
........  ...   .. ....|. |  ..|       .....|.  . . |.  . . ..|..|...   . ..||.|| | || |.| |.|.|. .|
sievedsytgprlsfkltpdlvkelveafkekk-------qleakevlelleeakellkkepnlleveap---itvcGDihGqfdDLlrlfdinglppae

-HYVFLGDYVDRGRQGIETVMLLMAYHCLYPDHLFLCRGNHEDYNTTMTYGFFDECRMKYgKKGTLAWLHIINAFNHLPLAALILDKVLCMHGGISPHIQ
.||||||||| . .|...||.|...|||...|| |||||. . .. ||| .|.. || |||.  .  . ..|| ||||||| .|.||.|||.||....|.
nkylFlGDyVDRGkfsvEvilllfalkllypsrffllRGnhEsrsvnkvygfyeevksky-kkgeeiyelfqevFnwLPlaalidekilcvhGGlspelt

KLEDIDKIQRPTFIPSYGLACDLVWSDPEKtsNVGWSLSARGISFSFDDITIEKFCQDNGLDLIVRAHQISSEmirgGHKWHANGRMVTIFSAANYLS-M
.|.||.||. .|. ||.|||.|||||.  . ||. ..||..| | .  .|||.. |.||||.|||..  |    | ...||...||||||.||.. ..| 
sldqirkierpleppkegllcdllWsdpee--qkgwkpnkRGvgfvFgpdavekflkknnldliiRahevvee----GyeffanrklvTifsapnYcgey

GNDSCVIRIDEQKTMQFCLLRPVKK
 .|...|.. .... ...|.|.   
snkaavlkvdknlklsivqfkpskh
Phosphatase Y40H4A.2.AA PP2Ac 48-328 36 7.3e-96 325.7 SMART 1-321 (321) Show / Hide 
Range on Protein: 48-328
Range on HMM: 1-321/321
Sequence Identity: 36% (117 aa)

VSKEEIRIISNYAAASFGSFSTLMRVD--EDCLPVHIVGDLHGHFGDLRRIF---GIHG-APGISHYVFLGDYVDRGRQGIETVMLLMAYHCLYPDHLFL
..|.||. . ..... | . .....|.  ..  || ..||.|| | || |.|    . |  |. . ||||||||||| ..||...|| .|. .||.. ||
MHKHEIYQLCHEVKEIFRQEPNMVEVEETPT-PPVTVCGDIHGQFDDLLRLFKKEDKNGKPPPYTNYVFLGDYVDRGPWSIECICLLFCYKICYPNNFFL

CRGNHEDYNTT---MTYGFFDECRMKYGKKGTLAWLHIINAFNHLPLAALILDKVLCMHGGISP------HIQKLEDIDKIQR----PTFIPSYGLACDL
 |||||. . .   ..|||.|||  ||..|  .....  ..|. .||.||| .|.||||||.||      ||. |.|| .| |    |  .|  ||.|||
LRGNHECRHMNMWVQYYGFYDECKRKYYHKRIWKIFQ--ECFSWMPLCALINNKILCMHGGLSPRECQTDHIHTLDDIRNIDRPQHPPQEPPDWGLMCDL

VWSDP------EKTSNV-GWSLSA-RGISFSFDDITIEKFCQDNGLDLIVRAHQISS-EMIRGGHKWHANG-----RMVTIFSAANYLS-MGNDSCVIRI
 ||||        . .| ||. .. ||.|. |     ..||. |.||||.||||     |   |... ...     ...||||| ||.  ..|  .|...
LWSDPVDFQWFHDDQWVPGWQPNCMRGMSYYFGPDVVDEFCKKNNLDLIIRAHQCVQYQM-MDGYEFWHDRDTRVHKLITIFSAPNYCDQCDNHAAVMKV

----------DEQKTMQFCLLRPVK
          |..   .| ...|..
NDHKVIQYKMDKNLKCHFVQFKPQM
Phosphatase Y40H4A.2.AA Subfamily.PPP1C.PD 49-327 43 6e-84 271.6 In-house 2-270 (271) Show / Hide 
Range on Protein: 49-327
Range on HMM: 2-270/271
Sequence Identity: 43% (122 aa)

SKEEIRIISNYAAASFGSFSTLMRVDEdclPVHIVGDLHGHFGDLRRIFGIHGAPGISHYVFLGDYVDRGRQGIETVMLLMAYHCLYPDHLFLCRGNHED
...||| . . |   | |  .|....    |..||||.|| . || |.|   | |  |.|.|||||||||.| .||..||.||.  ||...|| ||||| 
keaeirklclkareiflsqpillelea---plkivGdihGqyadllrlfekggfppesnylflGdyvdrGkqsletivlllaykikypenffllrGnhec

YNTTMTYGFFDECRMKYGKKgtlAWLHIINAFNHLPLAALILDKVLCMHGGISPHIQKLEDIDKIQRPTFIPSYGLACDLVWSDPEKTSnVGWSLSARGI
 . .  |||.|||. .|  |    |  ....|| ||.||.. .|..|.|||.||....||.| .|.||| .|. || |||.||||.|.. .||. . ||.
asinriygfydeckrrynik---lwktfvdcfnclpvaaivdekifcvhGGlspdlksleqirriarptdvpdkGllcdllwsdpdkev-kgwgendrgv

SFSFDDITIEKFCQDNGLDLIVRAHQIssemIRGGHKWHANGRMVTIFSAANYLS-MGNDSCVIRIDEQKTMQFCLLRPV
||.|.   .|||.. . |||||||||.    .  |... |. ..||.||| ||   . | ..|. .||.  ..| .|.| 
sftfgadvvekflkkhdldlivrahqv----vedgyeffakrqlvtlfsapnycgefdnagavmsvdeellcsfqilkpa
Phosphatase Y40H4A.2.AA Subfamily.PPP_Nematode_6.PD 50-327 37 1.3e-78 253.8 In-house 3-271 (272) Show / Hide 
Range on Protein: 50-327
Range on HMM: 3-271/272
Sequence Identity: 37% (104 aa)

KEEIRIISNYAAASFGSFSTLMRVDEdclPVHIVGDLHGHFGDLRRIFGIHGAPGISHYVFLGDYVDRGRQGIETVMLLMAYHCLYPDHLFLCRGNHEDY
.||.  . . |   | . ..|. |.    |... ||.|| . || |.|   | |  . |.||||||||||| .|...||.||.|...|| |||||     
eeellkllelakkvfkkqkslvevea---pikvcGdihGqysdllrlfdkggfppdanylflGdyvdrGrqslevillllaykvkfpnnffllrGnhece

NTTMTYGFFDECRMKYGKkgTLAWLHIINAFNHLPLAALILDKVLCMHGGISPHIQKLEDIDKIQRPTFIPSYGLACDLVWSDPEKTSnVGWSLSARGIS
 .|||.||.. .| .  |  . .  ..||.|||.||. ...||||||.|.....|... ...||.  ..  || ||.|||||..   ||. ..||.|  |
ainrvyGfydevqrryks--trlyaafqevfnalpltalvsgrilcmhGGlskklksldqlrelkrpldskeeslaidllwsdpenav-kgwaensrGvs

FSFDDITIEKFCQDNGLDLIVRAHQIssemIRGGHKWHANGRMVTIFSAANYLS-MGNDSCVIRIDEQKTMQFCLLRPV
 . ...|....  .||..||||.    .. |... |. ..|||||| .|.  . | ..|...||. .. | .|.|    
vvfGedavkkllekldidlvarahqv----vqdGyeffaekklvtifsaphycgqfdnaaavmkvdeklvvsfevlkpe
Phosphatase Y40H4A.2.AA Subfamily.PPP4C.PD 78-324 42 2.7e-76 246.3 In-house 28-267 (271) Show / Hide 
Range on Protein: 78-324
Range on HMM: 28-267/271
Sequence Identity: 42% (103 aa)

LPVHIVGDLHGHFGDLRRIFGIHGAPGISHYVFLGDYVDRGRQGIETVMLLMAYHCLYPDHLFLCRGNHEDYNTTMTYGFFDECRMKYGKKgtLAWLHII
|| . ||.|| | ||...| . |     .|.||||.||||   .|| .||.|... |||.. | |||||  . | .|||.|||  |||.| .  . |..|
spvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesrqitqvygfydeclrkygsa--evwryct

NAFNHLPLAALILDKVLCMHGGISPHIQKLEDIDKIQRPTFIPSYGLACDLVWSDPEKTSnvGWSLSARGISFSFDDITIEKFCQDNGLDLIVRAHQISS
.|||.| .|..|.|||.||.|..|..|  |.| . .|  |  |||.|||||...  ||..| ||  . | . ..|.|...|...||.||||.  |    |
evfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpedae--gwavsprgagylfgsdvveqfneandielicrahqlvm

EmirgGHKWHANGRMVTIFSAANYL-SMGNDSCVIRIDEQKTMQFCLL
.|.| | ...|..|| ||    || ......||.   .| ..      
e----gyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkif
Phosphatase Y40H4A.2.AA Subfamily.PPP_Nematode_4.PD 49-325 38 6.1e-74 238.6 In-house 2-268 (271) Show / Hide 
Range on Protein: 49-325
Range on HMM: 2-268/271
Sequence Identity: 38% (107 aa)

SKEEIRIISNYAAASFGSFSTLMRVDEdclPVHIVGDLHGHFGDLRRIFGIHGAPGISHYVFLGDYVDRGRQGIETVMLLMAYHCLYPDHLFLCRGNHED
.||||  .   | | | . ..|. ..    |. .|||||. | || |.| . | .    .|||||||||| ||||...||....  |.|...| ||||| 
tkeeiisvireaeaifsdekalveiea---pikvvgdlhaqfqdlirlfdllgrvpeeklvflgdyvdrgpqgievlillfclkiryrdrivllrgnhei

YNTTMTYGFFDECRMKYGKKgtlAWLHIINAFNHLPLAALILDKVLCMHGGISPHIQKLEDIDKIQRPTFIPSYGLACDLVWSDPEKtSNVGWSLSARGI
 .    |||..|| .|||..    | .. ..||.||..|||  ||||||||.||..  |...| .|   .  ||  ||.|.||.. .  .|  |.||||.
asvnkkygfyeecvtkygee---lwadfqrcfnrlpisaliakkvlcmhgglspelisldelrnipkpienldrgllidllwadpdn-kveewkasirgi

SFSFDDITIEKFCQDNGLDLIVRAHQisseMIRGGHKWHANGRMVTIFSAANYLS-MGNDSCVIRIDEQKTMQFCLLR
 |    .|. |.  ..|||.||||    ..  |..  .  ...|.||. || . . | ..|...||.  ...  |   
sytfgkgvvedvckslevdliirahq----vvqdgyevlsgrklitvfsvpnycaqfknaaavlkldenleislvalv
Phosphatase Y40H4A.2.AA Subfamily.PPP6C.PD 77-327 40 2.1e-69 223.6 In-house 27-270 (271) Show / Hide 
Range on Protein: 77-327
Range on HMM: 27-270/271
Sequence Identity: 40% (101 aa)

CLPVHIVGDLHGHFGDLRRIFGIHGAPGISHYVFLGDYVDRGRQGIETVMLLMAYHCLYPDHLFLCRGNHEDYNTTMTYGFFDECRMKYGKkgTLAWLHI
|| ..||.|| | ||  .|   |    ..||||||.||||   .||. .|.. .  |||.. | |||||  . |  |||.|||  |||.. || .... |
sspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesrqitqvygfydeclnkygn--anawkyc

INAFNHLPLAALILDKVLCMHGGISPHIQKLEDIDKIQRPTFIPSYGLACDLVWSDPEKTSNvgWSLSARGISFSFDDITIEKFCQDNGLDLIVRAHQIS
. |..||.| ..|||.|||.||... |..|  |.| . ||  |  |||||||||. ..  |..|.||  . | .   ..|.. | |.||.||||. .|  
tkvfdlltiaaiideqvlcvhgglspdvktldqirvieraqeiphkgafcdlvwsdpedvet--wavsprgagylfgskvtkefvhinnlklicrahqlv

SEmirgGHKWHANGRMVTIFSAANYL-SMGNDSCVIRIDEQKTMQFCLLRPV
  | |.. . ..||..|| ||    || .... ...... .. |.. |    
ee----glkymfdeklvtvwsapnycyrcgniasilaledaeereaklfkav
Phosphatase Y40H4A.2.AA Subfamily.PPP2C.PD 72-326 40 3.4e-68 219.7 In-house 22-269 (271) Show / Hide 
Range on Protein: 72-326
Range on HMM: 22-269/271
Sequence Identity: 40% (103 aa)

RVDEDCLPVHIVGDLHGHFGDLRRIFGIHGAPGISHYVFLGDYVDRGRQGIETVMLLMAYHCLYPDHLFLCRGNHEDYNTTMTYGFFDECRMKYGKKGtl
| |   || ..||.|| | ||  .| | |    . |.|.|||||||   .||| ||.| .  |.. . . |||||  . |  |||.||||||.     | 
nvkevkcpvtvcgdvhgqfhdllelfriggkspdtnylfmgdyvdrgyysvetvtllvalkvrykeritilrgnhesrqitqvygfydeclrkygnan--

AWLHIINAFNHLPLAALILDKVLCMHGGISPHIQKLEDIDKIQRPTFIPSYGLACDLVWSDPEKtsNVGWSLSARGISFSFDDITIEKFCQDNGLDLIVR
.. . |..|||.||. ....|.|||.||.|. |..| ...|   .|  |  |||.||||.     ||..| ||  ..|.   |.| . ||| |. ||||.
vwkyftdlfdylpltalvdnqifclhgglspsidtldkiraldrlqevphegpmcdllwsdpdd--rggwgisprgagytfgkdiseefnktngltlvsr

AHQISSEmirgGHKWHANGRMVTIFSAANYL-SMGNDSCVIRIDEQKTMQFCLLRP
  |    |..|  .  .|||||| ||    || .... .|.. ...|    |    
ahqlvme----gynwshdrnvvtifsapnycyrcgnqaailelddelkysflqfdp
Phosphatase Y40H4A.2.AA Subfamily.PPP_Nematode_5.PD 78-327 37 3e-66 213.1 In-house 28-273 (274) Show / Hide 
Range on Protein: 78-327
Range on HMM: 28-273/274
Sequence Identity: 37% (92 aa)

LPVHIVGDLHGHFGDLRRIFGIHGAPGISHYVFLGDYVDRGRQGIETVMLLMAYHCLYPDHLFLCRGNHEDYNTTMTYGFFDECRMKYGkkgTLAWLHII
|. ||||.|| ..|| |||   ||.   .|.||||||||| . .| ..||...  .|| .. | |||||  .   .||| .| . |..      . .  .
apitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrgnhevkkinklygfkeelkkkrq---eslykkfn

NAFNHLPLAALILDKVLCMHGGISPHIQKLEDIDKIQRPTFIPSY--GLACDLVWSDPEKTSNVGWSLSARGISFSFDDITIEKFCQDNGLDLIVRAHQI
 |..||| | .  ..|||||||||... |...  ...||   .   ||  ||.|.|||| ..|.||  | . .......  ..|||||||..| |    |
dvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkiraisvvfGkkevddllkkldidlivrahev

SSEmirgGHKWHANGRMVTIFSAANYLS-MGNDSCVIRIDEQKTMQFCLLRPV
... .. |.||.|||. |     | ..|. ...   ..|  |.|         
see----Gyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkpe
Phosphatase Y40H4A.2.AA Subfamily.PPP3C.PD 53-316 37 2.4e-65 210.5 In-house 6-272 (292) Show / Hide 
Range on Protein: 53-316
Range on HMM: 6-272/292
Sequence Identity: 37% (101 aa)

IRIISNYAAASFGSFSTLMRVDEdclPVHIVGDLHGHFGDLRRIFGIHGAPGISHYVFLGDYVDRGRQGIETVMLLMAYHCLYPDHLFLCRGNHEDYNTT
.  | . ||. . . .||..|.    |. ..||.|| | || ..| . | |  ..|.|||||||||   ||.|. |.|  . ||..||| |||||    |
alkiieeaakllkkeetllevea---pitviGdihGqfydllklfevgGkpastkylflGdyvdrGyfsiecvlylyalkiaypsrlfllrGnhecrhlt

MTYGFFDECRMKYGKKgtlAWLHIINAFNHLPLAALILDKVLCMHGGISPHIQKLEDIDKIQRPTFIPSYGLACDLVWSDPEKTS------NVGWSLSAR
  . | .|...||...    . .....|. ||||||. .| ||.|||.||.|..|.||.|..|   .|..|  |||.||||.        .     |.||
eyftfkeevkikysee---vyealmesfdslplaallnqkflcvhGGlspeikslddikkldrfkeppasGplcdllwsdpledygeeetseeflpnsvr

GISFSFDDITIEKFCQDNGLDLIVRAHQISSEMIRGGHKWHAN--GRMVTIFSAANYLSMGN-DSCVIRIDEQ
 |. .   .. .| |.| |  |.|||.   .  |  .| .|     ..|.|||.||| . |  . |...... 
GcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfpslitlfsapnyldvynnkaavlkyenn
Phosphatase Y40H4A.2.AA Subfamily.PPP_Nematode_3.PD 105-327 40 4.6e-65 209.7 In-house 92-307 (308) Show / Hide 
Range on Protein: 105-327
Range on HMM: 92-307/308
Sequence Identity: 40% (91 aa)

ISHYVFLGDYVDRGRQGIETVMLLMAYHCLYPDHLFLCRGNHEDYNTTMTYGFFDECRMKYGKKgtlAWLHIINAFNHLPLAALILDKVLCMHGGISPHI
..|.|||||||||   || |.||.|.. ||||..|| |||||  .  . |||. |.. .| ..    .    .||| |||.|.. .|.|||||||| .. 
ykkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysaa---lyeafqlafnvlplcavvnkkilcmhGGiseel

QKLEDIDKIQRPTFIPSYGLACDLVWSDPEKTSnVGWSLSARGISFSFDDITIEKFCQDNGLDLIVRAHQIssemIRGGHKWHANGRMVTIFSAANYLS-
.|. .||..||. ||  |. .||.|.||...   |.  |||| .. | . ....|..   |||.|||||.    .. |... |. ..|||||| .|   .
ldlkqldklkrpldipdvGvladltwadpdaev-kgykesarGagkvfGakavkeflkkldldlvvrahqv----vedGyeffadrklvtifsapsycGq

MGNDSCVIRIDEQKTMQFCLLRPV
 | ..|...|..  . . .|||  
ldniaavlsvdkklvisltvlrpe
Phosphatase Y40H4A.2.AA Subfamily.PPP5C.PD 49-317 36 6.2e-64 205.9 In-house 72-334 (346) Show / Hide 
Range on Protein: 49-317
Range on HMM: 72-334/346
Sequence Identity: 36% (99 aa)

SKEEIRIISNyAAASFGSFSTLMRVDED-CLPVHIVGDLHGHFGDLRRIFGIHGAPGISH-YVFLGDYVDRGRQGIETVMLLMAYHCLYPDHLFLCRGNH
|  ..|... | . . . ..|. .. .    . . ||.|| | ||  || ..| |. .. |.| ||.||||   .|....|.... |||.|.|| |||||
kkyalkille-akellkklpslveitipetkkitvCgdihgqfyDllnifelnGlpseenpylfngDfvdrGsfsveviltllgfkllypnhfflsrGnh

EDYNTTMTYGFFDECRMKYGKKgtLAWLhIINAFNHLPLAALILDKVLCMHGGIS-PHIQKLEDIDKIQRPTFIPSYGLACDLVWSDPEKtsNVGWSLSA
  |    ||| .|...|| .|  .| |   . || |||| .| .||| .|||.   .  .|.|. ||.| .  |. || ..|.||||..  . | | | |
esdnmnklyGfegevkakytek--vadl-ftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeeglllellwsdpqe--anGrspsk

RGISFSFDDITIEKFCQDNGLDLIVRAHQISSEmirgGHKWHANGRMVTIFSAANYL-SMGNDSCVIRIDEQK
|... |     .||...|.|.||.|.|.. .|    | . . .|...|.||| ||  .||| ...|.. ... 
rGvgiqfGpdvtkkflkennleliirshevkee----GyevehdGklitvfsapnycdqmgnkgafitlrgdd
Phosphatase Y40H4A.2.AA Subfamily.PPP_Nematode_7.PD 54-326 34 4.7e-56 179.9 In-house 7-294 (296) Show / Hide 
Range on Protein: 54-326
Range on HMM: 7-294/296
Sequence Identity: 34% (98 aa)

RIISNYAAASFGSFSTLMRVdedCLPVHIVGDLHGHFGDLRRIF----------GIHGAP-GISHYVFLGDYVDRGRQGIETVMLLMAYHCLYPDHLFLC
. . . . | .  ||...    .|| ||||.||.. || ||            . . .   ...||||||||||.. ||. |..|.  ||| ...| |||
lslidavkelfkkektlaei---spPvtivGdihGqyeDLvriLnarvskeeakqksalsfvrkkfvfLGdYvdrGsksieCisLvfalkilyptkyill

RGNHEDYNTTMTYGFFDECRMKYGKKGTL-AWLHIINAFNHLPLAALILDKVLCMHGGISPHIQKLEDIDKIQRPTFIPSY-GLACDLVWSDPE------
||      .|.|  |   . .|. .   . .  ..| ..|||||. .|.||.||||||...||||..|.|| .  .   || ||...||         ..
rGnhetkainfayefreelenrlskidgkeiyekfnevfsfmplaalvgekilcvhggispklesledinsierPlaevtedslakdllfadpldvqlla

-KTSNVGW-SLSARGISFSFDDITIEKFCQDNGLDLIVRAHQisseMIRGGHKWHANGRMVTIFSAANYLS-MGNDSCVIRIDEQKTMQFCLLRP
.  . .   ||.|..|..  .|..|. ..|.|||||||.|  |.|. |. ...|||||..|   ..|   |.... .  ..   ||.        
avsekpkyeknevrglsvvfneaavedvCrklnlklivrahq----kipegfkffadkkLltifsaprymnesdnsgavlkveangklsiaslrn
Phosphatase Y40H4A.2.AA Subfamily.PPP7C.PD 80-217 43 2.8e-38 121.4 In-house 70-207 (338) Show / Hide 
Range on Protein: 80-217
Range on HMM: 70-207/338
Sequence Identity: 43% (60 aa)

VHIVGDLHGHFGDLRRIFGIHGAPGIS-HYVFLGDYVDRGRQGIETVMLLMAYHCLYPDHLFLCRGNHEDYNTTMTYGFFDECRMKYGKKGTLAWLHIIN
| . |||||.. ||  |.   | |  .  ||| ||.||||....| ...|.|.  .|| ...| |||||||   . |||  | . || ..|.     . .
vtvcgdlhgklddlllilyknGlpsaenpyvfnGdfvdrGkesveillilfalllvypkevylnrGnhedyilnlryGfikeveskykvhgkkilrlled

AFNHLPLAALILDKVLCMHGGISpHIQKLEDIDKIQRPT
 |  ||||.|| .|.| .||||| .. .|| .|||.|  
vfawlplatlidekilivhGGis-dktdlelldkiersk
Phosphatase Y40H4A.2.AA Metallophos 78-277 25 3.6e-36 131.29 Pfam 1-124 (124) Show / Hide 
Range on Protein: 78-277
Range on HMM: 1-124/124
Sequence Identity: 25% (50 aa)

LPVHIVGDLHGHFGDLRRIFGIHGAPGISHYVFLGDYVDRGRQGIETVMLLMAYHCLYPDHLFLCRGNHEDYNTTMTYGFFDECRMKYGKKGTLAWLHII
... ..||.||...||.|.| |  . .. ...|.|||||||.. .|...||..|  .||.. ...||||.... .  |||. |           .| .. 
MRILHCGDIHGQYDDLNRLFEII-E-KPDFVIFTGDYVDRGPWSDECIWLLFCYKMNYPGPVYWVRGNHDYMHGNDFYGFY-E----------NDW-MWW

NAFNHLPLAALILDKVLCMHGGISPHIQKLEDIDKIQRPTFIPSYGLACDLVWSDPEKTSNVGWSLSARGISFSFDDITIEKFCQDNGLDLIVRAHQISS
. |  .||| |.  |.|||||..                                                           ||. ||.|...|.|.   
WWF-WMPLA-LDDWKILCMHGPP-----------------------------------------------------------FCK-NGVDYVIRGHTHVP
Phosphatase Y40H4A.2.AA Subfamily.PPP_Nematode_1.PD 78-324 21 1e-28 90.3 In-house 28-267 (273) Show / Hide 
Range on Protein: 78-324
Range on HMM: 28-267/273
Sequence Identity: 21% (53 aa)

LPVHIVGDLHGHFGDLRRIFGIHGAPGISHYVFLGDYVDRGRQGIETVMLLM-AYHClYPDHLFLCRGNHEDYNTTMTYGFFDECRMKYGKKGTLAWL-H
.| ..||. . ..|| .|. . | |   ...|||. .| |. . |....|. .  | || .... ||..|     .   ..| |...        |  ||
advtviGdirsryadlldilkltGwPfeqkilflGnlldsGkssleellillcskkc-yPknvvilrGeyetelvksdrrligelrvrfpdsnkwralna

II-NAFNHLPLAALILDKVLCMHGGISPHIQKLEDIDKIQRPTFIPSYGLACDLVWSDPEKTSNVgwslsARGISFSfDDITIEKFCQDNGLDLIVRahq
 .  ..||.||..  |.|....|.|. |.. ...  ..|  .        .. . | .. ||     . .  .  .   . . ..   .....|    | 
iikrllkrlPvaavlnkkllavysgvssnikekknvvavkrgiifenhstrvevqfldidiPsPv-----tendide-kskivkellkatdmsvmir---

iSSEMIRGGHKWHANGRMVTIFSAANYLSMG-NDSCVIRIDEQKTMQFCLL
...| |..   . |..|..||... .   |   |. || .. ..| |.   
-snsvvreGylftlknrlitltsatklqkdynnrGvvlsidkdlkvtfkli
Phosphatase Y40H4A.2.AA Subfamily.PPP7C.PD 226-319 30 2.4e-12 36.1 In-house 240-329 (338) Show / Hide 
Range on Protein: 226-319
Range on HMM: 240-329/338
Sequence Identity: 30% (28 aa)

CDLVWSDPEKTSNVgWSLSARGISFSFD-DITiEKFCQDNGLDLIVRAHQISSEmirgGHKWHANGRMVTIFSAANYLSMGN-DSCVIRIDEQKTM
|..||||....   .. . ||    |  |.| .|. |  .|.|..|.|.   |    |...  | ...|||||.||  .|      ......|   
ldilwsdpkaqeGc-kpntlrGgGsyfGpdvt-kkllqkynlellirsheckpe----GyefthnkkvltifsasnyyeeGsnrGayvklgkdltp
Phosphatase Y40H4A.2.AA Subfamily.PPP_Nematode_3.PD 78-104 52 5.2e-06 15.7 In-house 28-54 (308) Show / Hide 
Range on Protein: 78-104
Range on HMM: 28-54/308
Sequence Identity: 52% (13 aa)

LPVHIVGDLHGHFGDLRRIFGIHGAPG
|| ||||.|| | ||  .. ..| |  
apvtivGdihGqfedllalldlnGwpl
Sequence
Name Sequence Type Origin Length Description Download
Y40H4A.2.AA Protein None 333 None Fasta, JSON
Y40H4A.2.NA RNA None 999 None Fasta, JSON
Y40H4A.2.AA.PD_48-328 Protein Phosphatase Domain None 281 None Fasta, JSON