• Phosphatome.Net

Gene ptpB

ptpB
Species: D.discoideum
Alias: ptpB, DDB_G0277865
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: ClassicPTP_Unclassified
Protein domain

Protein domains of ptpB.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase ptpB.AA PTPc 26-349 28 4.5e-122 412.77 SMART 1-308 (308) Show / Hide 
Range on Protein: 26-349
Range on HMM: 1-308/308
Sequence Identity: 28% (108 aa)

CIDKEFNFILQKTELRALETD-----KFRSALEAKNK--LKNRYS-NVLPFEETRVKINIDDDDDDEDDNEDDIIVSNNNNNNNNNEKRIKRNSIGSSGQ
 . .||. . . |  .... .     ....|   .|.   ||||. .......||||.. .....                                   
GFWEEFERLQRMTPWDLMS-NYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGES-----------------------------------

SDVMSNSSDEEDHGGSGDEGTTLSDYINASFINN----GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEEN--------FKTKCDKYWPDKDEER
                  ...  ||||||..|.      .|||||||| .|| |||.|.|.|.. |||||....|.         . ||..||||. .. 
------------------HCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIEDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE-PMT

YGNFIVKFDNNITIPDILIRREFTLENLKD--------NKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKR---------------------SGP
||...|.. .  . ||  ..|.|...| ..        ..||...|..||.|||||.| |...||.|.  |.| ..                     .||
YGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGP

IVVHCSAGIGRSGTFVAIHSIVAKFAKHYDEKKQAPSINLPKLVVEMRNERPGMVQTRDQYRFCYLAISEAMN
||||||||.||.|||.||  .. .. .          ......| .|||.||||||| .||.||| .| |   
IVVHCSAGCGRTGTFCAIDIMCQQIEN----------VDIFQIVKMMRNQRPGMVQTEEQYIFCYRCILEYIK
Phosphatase ptpB.AA Y_phosphatase 56-346 33 2.3e-101 347.83 Pfam 1-243 (243) Show / Hide 
Range on Protein: 56-346
Range on HMM: 1-243/243
Sequence Identity: 33% (104 aa)

NKLKNRYSNVLPFEETRVKINIDDDDDDEDDNEDDIIVSNNNNNNNNNEKRIKRNSIGSSGQSDVMSNSSDEEDHGGSGDEGTTLSDYINASFINN-GT-
|| ||||....... ||||                                                             .|   ||||||..|.  .. 
NKEKNRYKDIPCYDHTRVKLQPI---------------------------------------------------------PGDEDSDYINANYIDGPYWN

---YICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFK-TK-CDKYWPD---KDEERYGNFIVKFDNNITIPDILIRREFTLENLKD--NKTRKIYH
   |||||||. .|| |||.|.|.|.. .||||....|. .  | |..||||    ....||.|.|.  .  .  .  . |.|...| .|  ..||...|
PKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQPMTYGDFQVTCVSEEH-CPDYTVRTFEVTN-GDQKQETRTVTH

FQYTTWPDHGTPVS-TTGFLKFVSFVDHEKR---SG--PIVVHCSAGIGRSGTFVAIHSIVAKFAKHYDEKKQAPSINLPKLVVEMRNERPGMVQTRDQY
..||.|||||.| | ....|.|.  | . ..   .|  |||||||||.||.|||.||  |.    .| ..       .....| .||| ||||||| .||
YHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCAID-IMCQQMEHEGTV------DIFQIVKHMRNQRPGMVQTEEQY

RFCYLAISE
.||| .| |
IFCYQCILE
Phosphatase ptpB.AA Subfamily.N_Choan_1.PD 39-349 38 2.6e-70 228.4 In-house 8-262 (262) Show / Hide 
Range on Protein: 39-349
Range on HMM: 8-262/262
Sequence Identity: 38% (100 aa)

ELRALETDKFRSALE-AKNKLKNRYSNVLPFEETRVKINIDDDDDdeddneddiivsnnnnnnnnnekrikrnsigssgqsdvmsnssdeedhggsgdeg
.|.....|.  .| .  .|.|||||||.  .. ||||.. .....|||||.|..    .  || ||||. ...|.||.|.|||. ..|||.||| |. | 
klaeigvdntataskadenvlknrysnivayDatrvkvtpneenk-------------------------------------------------------

ttLSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKD-EERYGNFIVKFDNNITIPDiLIRREFTLeN
|| .||||.. | ..|...||. .. . .   |.|.|.| . ....||.. ...||.||||| | .|. .|.| . |   ..|.   |.|.|||||.||.
--ntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvtreieagklkChryWPdenselklgdvtvkslseeekkt-yierkfkl-e

LKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFV--DHEKR-SGPIVVHCSAGIGRSGTFVAIHSIVAKFAkhydekKQAPSINLPKLVVEMRNERPG
||..|.  .| . .      ..|. ...  .| |.|.||  ||||  ||.| |.|. .|..                                       
resgetreveqlaytaWPdhGvPattkellefrkavlkatkkktkaplvihCsaGvGrtGtyialDrlvkave------ekaealdvkavvaelrkernl

MVQTRDQYRFCYLAISEAMN
                    
mvqtlvqyefvykavldald
Phosphatase ptpB.AA Subfamily.R_Anemone_2.PD 136-348 41 1.5e-68 222.8 In-house 50-261 (262) Show / Hide 
Range on Protein: 136-348
Range on HMM: 50-261/262
Sequence Identity: 41% (90 aa)

EGTTLSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYGNFIVKFDNNITIPDILIrREFTLE
||.. ||||||..|.    . .|| ||.|| .|| |||.|.||||| .|||||.|||. |.|...|||.|. . ||.  |. ...... | .. |.|...
egeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvl-rsfkvk

NLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDH---EKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFakhydekKQAPSINLPKLVVEMRNERP
. . ...|..  |.||.|||.|.| |....|..|  |..   |.  ||||||||||.|| |.|.|. ....        |.   ... . | ..|..|. 
rteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpivvhcsaGvGrtGvfiavdilleri-------kaealvdvfqtvkqlreqrn

GMVQTRDQYRFCYLAISEAM
||||.||| |.| .. ||. 
lmvqtkdqyefiydvlleal
Phosphatase ptpB.AA Subfamily.N6.PD 27-346 35 3.9e-66 214.9 In-house 14-292 (295) Show / Hide 
Range on Protein: 27-346
Range on HMM: 14-292/295
Sequence Identity: 35% (98 aa)

IDKEFNFIlQKTElrALETDKFRSALEAKNKLKNRYSNVLPFEETRVKINIDDDD-DDEDD-NEDDIIVSNNNNNNNNNEK-Rikrnsigssgqsdvmsn
. .||. . ||.|  . .. . ...  ..|| |||| |.|||..|||...  ...  ..|  | . | . ........| . ..  .|| |||.| .|. 
fweefeel-qkqe--seklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenvese-----------------

ssdeedhggsgdegttlsdyinasfINNGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDE-ERYGNFIVKFDNNITIPDI
|||.|.|..||..|||.|.| |  | || .||||. . ...|.|.  .. .  |  . |||....  ||...|.|.......|||||.| ..  .|.|..
-------------------------ehqkryiatqgcLkdtvsdFWrmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisEkstadY

LIrREFTLENL-KDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEK----RSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKhydeKKQAPSINLP
 |....    ..||||||||||||| |||. |  ...    ..    |.. | . ..|..| |.||| .||.| | |..                     
tl-RefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfledvnkkqeelekagpivvhcsaGiGrtGtfividivlkiieq----sgldvdidis

KLVVEMRNERPGMVQTRDQYRFCYLAISE
                             
ksikdvrsqrsglvqteaqykfvykavqf
Phosphatase ptpB.AA Subfamily.RB.PD 139-347 38 3.3e-64 208.4 In-house 52-259 (261) Show / Hide 
Range on Protein: 139-347
Range on HMM: 52-259/261
Sequence Identity: 38% (82 aa)

TLSDYINASFINN----GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKD-EERYGNFIVKFDNNITIPDILIrREFTLENl
. .|||||..|..      || ||||| .|. |||.|.||..|.||||||.  |. |.||..|||... .  ||.  |.  .. .  .  | |||..|. 
sdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmltqlvEkgkekceeYWPadeepvlyGdikvtllaekeldewvi-refkiek-

kDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEK----RSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKhydekkqAPSINLPKLVVEMRNERPG
 ....||. ....|.|||||.| .|.  |.||  |...      ..|||||||||.||.|||.|.. .. .  .          ....|.|.|.||  .|
-gkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHCsaGvGRtGtfialdrllqaiee-------ndyvdvfgvvaelReeRnl

MVQTRDQYRFCYLAISEA
|| .|| | . .. .   
lvqtekqyifiheclldl
Phosphatase ptpB.AA Subfamily.R_Sponge_2.PD 137-348 36 1.7e-63 206.2 In-house 48-261 (262) Show / Hide 
Range on Protein: 137-348
Range on HMM: 48-261/262
Sequence Identity: 36% (81 aa)

GTTLSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDK--DEERYGNFIVKFDNNITIPDILIRrEFTL
|.. ||||||||..    ...|| ||||| .|. |||.|.||.....|||||  ||| | || ||||.|  .| .||.| |.. .....|  || ...| 
gskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnleengkekcakYWPekvdeeveygkfkvtlkeeekladyiir-klkl

ENLKD-NKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHE---KRSGPIVVHCSAGIGRSGTFVAIHSIVAKFakhydekKQAPSINLPKLVVEMRNE
. |  ...... .|....||.|..| ..| .|.... | ..   .....|.|.||.|.||.|||.|..|....       |.  .|.. ... ..| .|.
skekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsdgvgrtGtfialdsvlerl-------kaeeeidvfevlktlrtk

RPGMVQTRDQYRFCYLAISEAM
|.||. .|| |.. |..|..  
riglvqdaaqYvfihdalleyi
Phosphatase ptpB.AA Subfamily.R_Anemone_1.PD 138-348 38 2.8e-63 205.6 In-house 50-257 (258) Show / Hide 
Range on Protein: 138-348
Range on HMM: 50-257/258
Sequence Identity: 38% (79 aa)

TTLSDYINASFINNG----TYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDkDEERYGNFIVKFDNNITIPDILIrREFTLENL
|||||||...      ..| ||.|| .|. |||.|.|.... .|||||  .|. |.|| .||||  .|.||.. |.  .. .|. | |...|.. | ...
deesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLtnliegekkkchqYwPd-stekygelrvslrkkevfadyii-rtlvlskk

KDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKR--SGPIVVHCSAGIGRSGTFVAIHSIVAKFakhydekKQAPSINLPKLVVEMRNERPGMV
|.......|.|||.| |  .|  |.... | ....  . |.|||||||.||.|.|..|.... .|.   ... . |  .|..|| ||||..|| |..||.
keteerevvqyhftvWpdkgvPqyatavLglrrkvqksslagarpvvvhCsaGvgRtGaflvidamleqa-------kkekvvDifnyvkairedrphmv

QTRDQYRFCYLAISEAM
 ||.             
qtkeqyvfihlavleal
Phosphatase ptpB.AA Subfamily.N12.PD 138-347 41 1.8e-62 202.5 In-house 57-268 (270) Show / Hide 
Range on Protein: 138-347
Range on HMM: 57-268/270
Sequence Identity: 41% (90 aa)

TTLSDYINASFINN----GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEER--YGNFIVKFDNNITIP-DILIRrefTL
.  ||||||.||..     .|| .|||| .|. |||.||||.| .|.||. || |. |.||..|||.. ||.  .|.| |. ... ..  |.|||   ||
eegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryWpeegeeelefgefevtleeekavdddflir---tL

ENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVD--HEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKhydeKKQAPSINLPKLVVEMRNERP
.  .....||.| |.|| |||||.| |..  |.... |   .|. . |.|||||||.|| || .||  .   . .    .| ...... .||.|.|..|.
kveaqkesrkvyqfhytaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellka----ekipeeldvfdlvlelrkqra

GMVQTRDQYRFCYLAISEA
 .|||..||.. | |. | 
alvqtkeqyelvykavael
Phosphatase ptpB.AA Subfamily.N5_RR.PD 56-346 29 2.5e-61 199.0 In-house 23-262 (265) Show / Hide 
Range on Protein: 56-346
Range on HMM: 23-262/265
Sequence Identity: 29% (89 aa)

NKLKNRYSNVLPFEETRVKINIDDDDddeddneddiivsnnnnnnnnnekrikrnsigssgqsdvmsnssdeedhggsgdegTTLSDYINASFIN-----
.. ||||...|| |..|| .. .. .                                                          .|.||||.|      .
sqtknryktilPnensrvllesesse--------------------------------------------------------dedssyinanyikGydee

NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDE----ERYGNFIVKFDNNITIPDILIRrEFTLENLKDnKTRKIYHFQY
 .|. ||||| ||| |||.||.......|||||. .|. ..|| .|.||. .    ||||.. .|... ..  |  .| ...|..|..  .|...|. ||
skayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdaedyeiserygdveikveeiverndysvr-klvlkyler-versvkhywy

TTWPDHGTPVSTTGFLKFVSFVDHEK-----RSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKhydekkqAPSINLPKLVVEMRNERPGMVQTRDQYRFCY
 |||| .| ... .|..|  |....     . .|.|||||||||| | |.||.  | .. .          ... |.|...| .| |||||..||.. . 
tdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiaisiavrqlre-------eivvdvlkivcnlrldrGGmvqtseqyelih

LAISE
|... 
ralcl
Phosphatase ptpB.AA Subfamily.N13.PD 141-347 35 1.9e-60 196.2 In-house 49-257 (259) Show / Hide 
Range on Protein: 141-347
Range on HMM: 49-257/259
Sequence Identity: 35% (77 aa)

SDYINASFIN------NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEER---YGNFIVKFDNNITIpDILIRREFTLE
. |||||.|.      . .|| .|||| .|. |||.|.|||....|.|.| | |. | ||..|||.. ...   .. . |.  .     | .|.......
ggyinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPerknkklkvsnrlevellkvqkl-dgfvvralavk

NLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKR-SGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYdekkqapSINLPKLVVEMRNERPGM
. ...|.. |.....|||||.| |.. ...||. | . .. .|||||||||||||||....|. ..   ...        ......| ..|. | |.|||
dsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqtdagPivvhcsaGiGrsGvlitidvvlglierdk-------efdvkeivrklreqrqgv

VQTRDQYRFCYLAISEA
.||| |.| || |.   
vqtkdqyifvykailev
Phosphatase ptpB.AA Subfamily.RA.PD 136-346 38 2.5e-60 195.7 In-house 50-263 (266) Show / Hide 
Range on Protein: 136-346
Range on HMM: 50-263/266
Sequence Identity: 38% (84 aa)

EGTTLSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYGNFIVKFDNNITIPDILIRrEFTLE
||.  |||||||||.      ..| .|||. .|. |||.|||||.|  |||||  .|  ..|| .||||.    ||.  |. ...  . |. .|.| .. 
eGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativmltelkerkeekcaqywpdeGlvtyGeirvevkdetvledytvr-dflvt

----NLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEK--RSG-PIVVHCSAGIGRSGTFVAIHSIVAKFakhYDEKKqapsINLPKLVVEMR
   . ...|.| .  | .|.||. | |... | ||..  | . .   .. |||||||||.||.|||... .....      |.|... . | ..|..|| 
qlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanhpivvhcsaGvGrtGtfivldavlerv---kaerk----ldvfeavkrlr

NERPGMVQTRDQYRFCYLAISE
||||  || |.| .. |     
lqrpqmvqtleqyefiykvlle
Phosphatase ptpB.AA Subfamily.RG.PD 134-348 38 9.4e-60 193.9 In-house 51-263 (264) Show / Hide 
Range on Protein: 134-348
Range on HMM: 51-263/264
Sequence Identity: 38% (86 aa)

GDEGTtlsDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKD-EERYGNFIVKFDNNITIpDILIRREF
| .|.   ||||||.|.    .  || ||||| .|| |||.||||.|..||||||  .|. . ..|.|||.||  ...... |.. .. .. ... |.|.
gkdgk---DYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivmltdldekgrrdedvyWPkkdeplelealkvtllskekl-skytvrdf

TLENLKDNKTRK--IYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKR--SGPIVVHCSAGIGRSGTFVAIHSIVAKFakhydekKQAPSINLPKLVVEMR
|.| ||.| ..  .....||.|||.|.| ||. .| ||   .. ..  .||||||.||| ||.||..|. ... ..       ....|. ...  .|..|
vlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaankeeaGPivvhdsaGvgragtyialdtllqql-------ekeeavnvyqvlklir

NERPGMVQTRDQYRFCYLAISEAM
||.|.|..||.| | |..|..   
akRpglvtteEqyvfiydallelv
Phosphatase ptpB.AA Subfamily.N3.PD 140-345 38 2.3e-59 192.4 In-house 49-257 (261) Show / Hide 
Range on Protein: 140-345
Range on HMM: 49-257/261
Sequence Identity: 38% (81 aa)

LSDYINASFIN---NG-----TYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDE-ERYGNFIVKFDNNiTIPDILIRREFTL
.|||||...|   ..      || ||||| .|  |||.|.|||.|..|||||   |. ..|| .|||....  ..|.| |.  ..       .||..|..
etdyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkChqyWPetedelefgefsvrceke-detksyvlrelvl

ENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEK--RSGPIVVHCSAGIGRSGTFVAIHSIVAKFakhydEKKQapSINLPKLVVEMRNERP
 . .. |||...||. ||||| | ... ||.||. | . .  .. |.||||||||||.| ....   .|.      |...  ......| .||. |  .|
kdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlilletalali-----eaae--pvypldivrtmrdqra

GMVQTRDQYRFCYLAIS
|| .||.|   ||    
mlvqtvsqykfvCeail
Phosphatase ptpB.AA Subfamily.R_Ecdysozoa.PD 137-346 36 3.1e-59 191.9 In-house 51-266 (269) Show / Hide 
Range on Protein: 137-346
Range on HMM: 51-266/269
Sequence Identity: 36% (82 aa)

GTTLSDYINASFINNG----TYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTkCDKYWPDKDEERYGNFIVKFDNNITIPDIlIRREFTLEN
|.  |||||||||.      ..|. |.|. .|| |||.||.||....||||. ..|. .  |.||||. || .||. .||. ... .|  |.||... . 
gkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivmlsnlteknrk-cakyWpiedevqygdilvklvseekhsdy-iireldvsk

LK---DNKTRKIYHFQYTTWP-DHGTPVSTTGFLKFVSFV-DHEKRS------GPIVVHCSAGIGRSGTFVAIHSIVAKFAKhydEKkqapSINLPKLVV
|    ...||.  ..||.|. |   | ...| ||... | ...| .      .||||||||| ||||.|||. ... .  .   |.    .... . | .
kkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgsrsPivvhCsaGvgrsgifvaldlllqqlka---ed----kvdifetvk

EMRNERPGMVQTRDQYRFCYLAISE
.|..|. .||  .|| |.| |. . 
kLrsqrnllvqsleqyvflyralad
Phosphatase ptpB.AA Subfamily.RK.PD 140-348 36 1.1e-58 190.1 In-house 55-266 (267) Show / Hide 
Range on Protein: 140-348
Range on HMM: 55-266/267
Sequence Identity: 36% (79 aa)

LSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTRE-EENFKTKCDKYWPDKDEERYGNFIVKFDNNITIPDIlIRREFTLEN--
||||||..|.       .| ||||| .|. |||......|.  |||||    |... || ||||.. | |||.. |.. .  .  |. . | |..|.   
ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmlteldvevgrvkClkyWPedtevrygdikvelveaeldadl-vvrifrvekla

LKDNKTRKIYHFQYTTWPDH-GTPVSTTGFLKFVSFVDHEKRS---GPIVVHCSAGIGRSGTFVAIHSIVaKFAkhydekKQAPSINLPKLVVEMRNERP
. ...|.. .||...||.. ..||| ...||..  |.. .     |.|||||.|| ||||||.||.... . .      ..   .... | ..||... |
rgqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeeeeeGrivvhClaGaGrsGtfiaidivl-emi------eregvvdvfnavktlrnrkv

GMVQTRDQYRFCYLAISEAM
|.| .||.|.| .| ||.  
nmveteeqykfvydvileal
Phosphatase ptpB.AA Subfamily.N9.PD 136-346 36 1.5e-56 183.5 In-house 49-272 (275) Show / Hide 
Range on Protein: 136-346
Range on HMM: 49-272/275
Sequence Identity: 36% (80 aa)

EGTTLSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDK--DEERYGNFIVKFDNNITIPDiLIRREFT
.... ||||||.|..    . ..| ||||| .|. |||.|.|||.  .||| || .|. . || .|||..  . ...|.. |.  .  .  || ....| 
dedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmttrvvergrlkcgqywpleeessaefgdlsvsnveveveed-ykvrvle

LENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHE---------------KRSGPIVVHCSAGIGRSGTFVAIHSIVAKFakhydekKQAPSI
|....||. |||...|||.|.| |.. .|.... | ..                .  ||||||||||||.|||...   .|....   ... . |  .|.
iknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdeskghlsgPPivvhcsaGiGrtGtfitldiclarl-------eevgtv

NLPKLVVEMRNERPGMVQTRDQYRFCYLAISE
 |  ..|| .|| |||||. |           
dvvetvkllrtqrafsiqtpeqyefcylavle
Phosphatase ptpB.AA Subfamily.N23.PD 137-346 34 7.7e-56 181.2 In-house 127-347 (350) Show / Hide 
Range on Protein: 137-346
Range on HMM: 127-347/350
Sequence Identity: 34% (74 aa)

GTTLSDYINASFINNGT-----YICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDE--ERYGNFIVKFDNNITIpDILIRREFT
. .|||||... . |     .|.||||. .|. |||.|.||| |..|||||.|.|. |.|||.||| . .  . .|.. |   .  .  .|.| ..|.  
pgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslkslrss-egwiervlh

LENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEK-----------RSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYDEKkqapsiNLPK
. .. |.. |...|||...| | |   .|.|.  |..                ||..|||||.||.|||  ..|..... ..|.|..| ..|..|  |||
lqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagngii------nipr

LVVEMRNERPGMVQTRDQYRFCYLAISE
........| |. |              
vvrrlrqqRkymvqkkvilkklyeavle
Phosphatase ptpB.AA Subfamily.N1.PD 141-347 39 1.5e-55 180.2 In-house 52-266 (268) Show / Hide 
Range on Protein: 141-347
Range on HMM: 52-266/268
Sequence Identity: 39% (85 aa)

SDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERygnfIVKFDN------NI--TIPDILIRREF
||||||...    .  || ||||| .|.  ||.|.|||||  ..|| .  |. ..|| .||| ..||      .....       |   . ...| . ||
vdyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywpqeeeea----ellleetklkvkliseerksyflvrll

TLENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDH----EKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFakhyDEKKQAPSINLPKLVVEMR
.|....||.|.||.|||||| | | | . ||||.  | .     .  ||.|.|||||||||||.. . .....     ......... | ..|.|. | |
eLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsgtlslvdtclvei----ektgdlnavdikkvLlelR

NERPGMVQTRDQYRFCYLAISEA
..|| || || |.|| |      
kyRvGLiqtpdqLrFsyiaileg
Phosphatase ptpB.AA Subfamily.RN.PD 138-349 40 3.3e-53 172.2 In-house 52-264 (264) Show / Hide 
Range on Protein: 138-349
Range on HMM: 52-264/264
Sequence Identity: 40% (87 aa)

TTLSDYINASFIN-----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYGNFIVKFD-NNITIPDILIrREFTLE
.. |||||||.|      . .|| ||||| .|| |||.|.||| . .||.||| ||.  ..|..||||. .| |. . |..  . |   | |.| | | |
aeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylv-rsfylk

NLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDH--EKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYDEkkqapsINLPKLVVEMRNERPG
|. ..|| .  | . .||..|.| |.  .|.|   |.     || |||||||.| ||.|....|  ......|   |      |...  .|..|||.|.|
nlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlvlerllkGvke------idiaatlehlrdqrpg

MVQTRDQYRFCYLAISEAMN
.||..|.. |..| .|    
lvktkdqfefaltavaeevn
Phosphatase ptpB.AA Subfamily.RC.PD 124-347 29 1.3e-50 163.8 In-house 54-286 (288) Show / Hide 
Range on Protein: 124-347
Range on HMM: 54-286/288
Sequence Identity: 29% (71 aa)

SSDE--EDHGGSGDEGTTLSDYINASFINN----GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWpDKDEERYGNFIVKFDNNI
|.   ..   .  ..   |.|||||||.       || .|||| .|. |||.||.|.  ..|||||. .|  . || .|| .. .. ||.  |.....  
esehdsdessdddidseegskyinasfidsykkpekyiaaqGplketvddfwrmiferkvkvivmltelkeGdrekcaeyw-eeGkrayGdvevdlkdtd

TIPDILIRrEFTLENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVD------------HEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKhy
 .| ..|  . | | |. ..|.....|||.|.... |     .||..  |             ..  |.|..|||..| .|.|.|.|. ...        
kssdyilr-klelvnkkrkdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallalleslea--

dEKKqapsINLPKLVVEMRNERPGMVQTRDQYRFCYLAISEA
|.|    ... ..|...|..||.||.. .|| . | .. |  
-eek----vdvfqvvkklrkarplmvsveeqyillydvlvet
Phosphatase ptpB.AA Subfamily.N20.PD 141-346 42 1.6e-50 163.7 In-house 49-254 (257) Show / Hide 
Range on Protein: 141-346
Range on HMM: 49-254/257
Sequence Identity: 42% (90 aa)

SDYINASFI---NNG---TYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDK--DEERYGNFIVkFDNNITIPDILIRREFTLEN
||||||.|   | |    ||.||||||.|| |||.|. |.|||.| |.||| |    || .|||           | | | .|  | . .|| | . .  
kdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywpislkkplelkhfrv-flenyqilqyfiirmfqvve

LKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHydekkqaPSINLPKLVVEMRNERPGMVQ
   .. . ..|.| ||||||| |.  |.|.. .  . . .||.||||||||||.| |...  ...   |         |.|..| .||..| |||||..|
kstgtshsvkqlqftkwpdhgtpasadsfikyiryarkshltgpmvvhcsagigrtgvflcvdvvfcaivkn-------csfnimdivaqmreqrsgmvq

TRDQYRFCYLAISE
|.|||  . |    
tkeqyhfcydivle
Phosphatase ptpB.AA Subfamily.N_Choan_2.PD 138-347 32 3.5e-49 159.0 In-house 46-264 (266) Show / Hide 
Range on Protein: 138-347
Range on HMM: 46-264/266
Sequence Identity: 32% (74 aa)

TTLSDYINASFIN-----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERYGN---FIVKFDNNITIPDILIRREFT
.  . |||| ...     . .||...||| .|. .||.||||.... |||.|  ||. ..||..||| . .|.      .|  .  ..  .  |... .|
dsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkladgkikvlalseekeegyiltrlr

LENlkDNKTRKIYHFQYTTWPDHGTPVSTT------G---FLKFVSFVDHEKRS-GPIVVHCSAGIGRSGTFVAIHSIVAKFakhyDEKKqapSINLPKL
|.  ...||.. ||.|.|||||| | ..            |. |  | .| .  .|..||||||.||.||..||  .|       .|.|   .... ...
lek--kgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtliaiDiavrlL----eetk---kvdvlai

VVEMRNERPGMVQTRDQYRFCYLAISEA
 |.|..|. .||. .||.. | |..|  
ieelRkdRmalvqhpeqyellykavvey
Phosphatase ptpB.AA Subfamily.N14.PD 141-344 35 7.5e-48 154.7 In-house 53-270 (275) Show / Hide 
Range on Protein: 141-344
Range on HMM: 53-270/275
Sequence Identity: 35% (78 aa)

SDYINASFINN------GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDK----DEERYGNFIVKFDNNiTIPDILIRREFTL
..||||| |.        .|| .|||| .|. |||.|.|||. ..|||||.|||. |.|. ||.|..    .. ..|.| |    . .  | .| . ..|
tgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlteeeedgkeksfkylPkleskkktvefgkfkvttkfs-edsdsvittglkl

ENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVD----H--E------KRSGPIVVHCSAGIGRSGTFVAIHSIVAKfakhYDEKKQapsINLPK
. |  .. |...|.||| ||||| |   .|||.|.  |.    .  .      ... |..||||||.||.|  .    ..|... ..   |...| .  .
khlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvkeskPPvlvhCsaGvGrtGvlilsdlliat----lehnee---idikk

LVVEMRNERPGMVQTRDQYRFCYLAI
|. |  .|||  ||.| | ..     
vlarLrkqrmllvqtlaqykfvykvl
Phosphatase ptpB.AA Subfamily.N_Nematode_4.PD 141-348 31 4.1e-43 139.3 In-house 52-263 (264) Show / Hide 
Range on Protein: 141-348
Range on HMM: 52-263/264
Sequence Identity: 31% (66 aa)

SDYINASFIN---NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEE--RYGNFIVKFDN-NIT-IPDIlIRREFTLENL
||| ||..    . .|| ||||| .|. ||| |....  ...|||   .|.   || .|.|.|.|.  ..|.. ..  . .| |. | . ... | .   
ndyihaswmrmPdkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypeksekvvkfGkyritlvekkeeviadv-ilnslkvtnt

K---DNKTRKI--YHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKRSGPIVVHCSAGIGRSGTFVAIHsivakFAKHydEKKQAPSINLPKLVVEMRNERP
|  ....   |.|.. |.|. .|. ..  .|.   | ..|...|||||||||.||. |.| |..|.     .. ..|.. ..| |.|. | . ||.. |.
ekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkkkkkekPivvhcsaGvGrtatlvGid-----yati--rirenseievldivrelramrl

GMVQTRDQYRFCYLAISEAM
 | .. . | .         
kavqshlqflfllvvlielf
Phosphatase ptpB.AA Subfamily.R_Nematode_2.PD 149-341 32 5.7e-43 138.7 In-house 66-253 (261) Show / Hide 
Range on Protein: 149-341
Range on HMM: 66-253/261
Sequence Identity: 32% (63 aa)

INNGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEE--RYGNFIVKFDN-NITIPDILIRREFTLENLKD-NKTRKIYHF
|.  .|.||||| ||  ||| |.  .. . ||||..  |. |.||..|.| . ..  . |.| .|  . .  ..| . .| .|. .   .|| . |.||.
gnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthy

QYTTWPDHGTPVSTTGFLKFVSFVDHEKRsgPIVVHCSAGIGRSGTFVAIHSIVAKFAKHydekkqaPSINLPKLVVEMRNERPGMVQTRDQYRFCY
 |||.|.| | .   . .. | ....  ||||||||||||...|.... .  .  ..       |.|.| ... |.|. |.  .||. |. .     
qyeeWpdrgvPkshaelfeLlelvkksek--PivvhCsaGiGRtmafigteylarevead-------ptieltealkelrehRwkgiqtesqlywlt
Phosphatase ptpB.AA PTPc_motif 240-346 41 7.4e-43 149.61 SMART 1-92 (92) Show / Hide 
Range on Protein: 240-346
Range on HMM: 1-92/92
Sequence Identity: 41% (46 aa)

KIYHFQYTTWPDH-----GTPVSTTGFLKFVSFVDHEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYDEKKQAPSINLPKLVVEMRNERPGMVQTR
...|..||.||||     |.|    ..|.|.  | .     |||||||||.||.|||.|| ... .             ..  ..| |||..||||||| 
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-----PIVVHCSAGCGRTGTFCAIDMMMQQ-------------VDIFQTVKEMRKQRPGMVQTE

DQYRFCYLAISE
.||.||| .| |
EQYIFCYRCILE
Phosphatase ptpB.AA Subfamily.N_Nematode_1.PD 139-341 36 2.5e-42 136.6 In-house 50-257 (265) Show / Hide 
Range on Protein: 139-341
Range on HMM: 50-257/265
Sequence Identity: 36% (78 aa)

TLSDYINASFINN----GTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEERY--GNF--IVKFDNNITIPDILIRRE---
. |||| | ..        .||.|.|| .|| ||| |.  .. . |||| .  |. |.|| .|.| |..|.    .    .  .|....  .    |   
lpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlckliekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevik

FTLEN--LKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKrsGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHydekKQAPsiNLPKLVVEMRN
 |  .     .||||. |.|.| |||.| |    . |.... | ..|  |||||||||||||.|| |||. |. |...     || .  . .||| ..|.
vtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrgsk--gPivvhCsaGiGrtGtivaieyildklleg----kqie--dmeklvkkire

ERPGMVQTRDQYRFCY
.|   .||  || | .
qrnysiqtdaqylfvh
Phosphatase ptpB.AA Subfamily.R_Nematode_3.PD 141-346 26 7.9e-40 128.5 In-house 51-264 (267) Show / Hide 
Range on Protein: 141-346
Range on HMM: 51-264/267
Sequence Identity: 26% (60 aa)

SDYINASFIN---NGTYICTQGPL--------LNTIVDFWKMIWEQNSNIIVMLTREEE---NFKTKCDKYWPDKDEE--RYGNFIVKF-DNNITIPDIL
.|.|.|....   .   | ||.|.         .||  ||.|| .......|||    |   . . || .|.|.| ..  . ... ||  |..    .  
ddfihAnvvecpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeeekcseYypekvdgelkfegvsvkctdikkelsedv

IRREFTLeNLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKrsGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYDekkqapSINLPKLVVEM
 .|.... .....|. .. | .|. |.....| ..  .|. . || . |   |.|||||.||.||.|..||.  . ...|. .      ...| .|. |.
ekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfveksk--tpvvVHCsdGisRsatlaaielgyqliikskg------kldllslikel

RNERPGMVQTRDQYRFCYLAISE
|. |.| .||  .. |  | | .
rkqRagaiqtelelafvilgilk
Phosphatase ptpB.AA Subfamily.N_Nematode_6.PD 143-342 33 9.9e-38 121.6 In-house 50-246 (253) Show / Hide 
Range on Protein: 143-342
Range on HMM: 50-246/253
Sequence Identity: 33% (68 aa)

YINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDK--DEERYGNFIVKFDNNITIPDILIRR-EFTLENLKD
|| |....    .  .||||.|| .|| .|||||  . .. ||||    |. | |. .| .||  |. .....  . . . .| .. |    .    |..
yihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvGdarkitklctvikigrkdidkilvrslkrivkagd

NKTrKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEKRsgPIVVHCSAGIGRSGTFVAIHSIVAKFAKhYDekkqapSINLPKLVVEMRNERPGMVQTRD
. .. |...  ||||| | | .  |...| | ..|.  |||||||||.|| ||.. | .|.. . .|       .....|.| .|.||   |||  || .
eev-ivkhihWanWPdhGvPdsflsalrllsvvkkdkk--PivvhCsaGvGrtGtlaliliilealrl-pd------fqgvkdllvklreerfravqtev

QYRFCYL
 .     
qylyalr
Phosphatase ptpB.AA Subfamily.N_Nematode_5.PD 140-344 26 9e-32 101.9 In-house 48-253 (258) Show / Hide 
Range on Protein: 140-344
Range on HMM: 48-253/258
Sequence Identity: 26% (55 aa)

LSDYINASFIN----NGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCdKYWPDKDeERYGNFIVKFDNNITIPDILIR-REFTLENLK
..||||| |.    . ..| || || .|. |||.|. ... . .|.|...||  .|.. ...|..  . | |.   | || ..|.|.| | .  .    .
ddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllvedeelketav-sffplet-gdylnlgkmfinnrkvevkedekkeytvevlp

D--NKTRKIYHFQYTTWPDHGTPVSTTGFLK--FVSFVDHEKR-SGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHyDEKKqapsinLPKLVVEMRNERPG
 . ..|||...  | ...  .|    .......  . |.||....|.||.|||...  .. .  .   | .      . ... ..|..|||.|.. .|| 
egcsesvfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgknapvvvvsdlGlgRagtflllsvaieqlnng-kepn------ideilkkirsqRpg

MVQTRDQYRFCYLAI
. | |.         
avesliqyasvyaav
Phosphatase ptpB.AA Subfamily.N_Nematode_egg.PD 43-344 23 2.7e-23 74.4 In-house 13-252 (257) Show / Hide 
Range on Protein: 43-344
Range on HMM: 13-252/257
Sequence Identity: 23% (60 aa)

LETDKFRSALEAKNKLKNRYSNVLPFEETRVKINIDDDDDDEddneddiivsnnnnnnnnnekrikrnsigssgqsdvmsnssdeedhggsgdegttlsD
..   .. |... .. | |   |   | .|||...      .|.| | ... .    ..|..| || ||  |||.|..... . |||||   |.   .|.
vdeislttaasdnylekarskrvhckessrvklelrrGqyld---------------------------------------------------------d

YINASFINNG----TYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENfkTKCDKYWPDKDEE--RY--GNFIVKFDNNITIPDILIRRE-FTLeNL
 |||  ..|  ..  |.. ..  .  . .| |.|   . |    |.. . . |.|.  .   .   |    |.        . | |.||..  |. ...|
fihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmltsakes--erceyywpkaeseslvtvpGslrienlkvdskadplfrvtklkl-vG

KDNKTRKIYHFQYtTWPDHGTPVSTTGFLKfvsfvDHEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHyDEKKQapsiNLPKLVVEMRNERPGMVQT
.|||   . .. .     |.     . . || .| .|.  |..  .| | |  .                                              
gddeelflehwqg-dvnylsdvysplrvlr-----klrnlskpvvvqdilGvskaatlvaieiallsllrG-pitks----lvlravvflrlrrrlsves

RDQYRFCYLAI
           
vllylfvyrlv
Phosphatase ptpB.AA Subfamily.N_Fungi_PTP1.PD 56-215 23 2e-20 64.6 In-house 45-162 (343) Show / Hide 
Range on Protein: 56-215
Range on HMM: 45-162/343
Sequence Identity: 23% (38 aa)

NKLKNRYSNVLPFEETRVKINIDDDDDdeddneddiivsnnnnnnnnnekrikrnsigssgqsdvmsnssdeedhgGSGDEGTTLSDYINASFINNG---
||||.|.||.| .|||..                                                        . .  ..|||||....          
lfaknrYknilPYehsrvkLkkslkss-------------------------------------------------dakkhslstnDYinanYlkltrfs

-------TYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDeerYGNFIVKFDN
   || ||.|| .|. ||.|.| . . ..|..|| . |.   ||..||.. .   | .. ||..      
veinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyrYWqegs---ydditvklas
Phosphatase ptpB.AA Subfamily.N_Fungi_PTP1.PD 239-344 28 3.9e-18 57.1 In-house 213-338 (343) Show / Hide 
Range on Protein: 239-344
Range on HMM: 213-338/343
Sequence Identity: 28% (36 aa)

RKIYHFQYTTWPDHGTPVSTTGFLKFVS----FVD--------HEKRSGPIVVHCSAGIGRSGTFVAIHSIVA------KFAKHYDEKKQAPSIN--LPK
..|..|.  |.| .. .    .|. .     ..|        ...|| ||.||||||.|| ||.|.. |..       .  |.. . ..|  ..  .  .
yevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisi

LVVEMRNERPGMVQTRDQYRFCYLAI
| |.|..|  |||. ||. |.| |. 
ivnelrkqrismvqnldqfifiYeal
Phosphatase ptpB.AA Subfamily.N_Nematode_eak.PD 142-264 34 1.6e-17 55.3 In-house 54-178 (281) Show / Hide 
Range on Protein: 142-264
Range on HMM: 54-178/281
Sequence Identity: 34% (42 aa)

DYINASFINN---G-TYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDEE-RYGNFIVKFDNNITIPDILIRREFTLEnlKDN
||||| ..    |  || |  .  . .. ||.|. ||.|  ||.|  . |.   | |||.||| |. .|| . |.  ..||  | . |.  | |.| ...
GyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdktevlkyGildverkeyavkrniletrllilr--kGn

KTRKIYHFQYTTWPDHGTPVSTtGFLKF
|...  | .  .|.    || .      
ethrvlhykvfGwtettlpkye-dflal
Phosphatase ptpB.AA Family.DSP.PD 180-346 16 1e-13 43.0 In-house 136-244 (387) Show / Hide 
Range on Protein: 180-346
Range on HMM: 136-244/387
Sequence Identity: 16% (29 aa)

IVMLTreeenfktkcdkywP------DkdeerygnfivkfdnnitipdilirreftlenlkdnkTRKIYHFQYtTWPDHGTPVSTTGFLKFVSFVDHEK-
|| ||                                                           . .|.. ..  ..||..|     | |.. |...  .
ivnlt--------------ddkpqftk-------------------------------------elgikylri-pidDhnapplenlfekaidfieegnd

RSGPIVVHCSAGIGRSGTFVAIHSIVAkfakhydekkqaPSINLPKLVVEMRNERPGMVQTRDQyRFCYLAISE
| ..||| ||.||||| ...  . .              ..|.. .  .|  |||... ...  . .|   |  
skgvVlVHCkaGkgRsgtliiaYlmks------------egltleealdwvrskRpgvitpnqg-flkqlkdle
Phosphatase ptpB.AA Subfamily.PTPDC1.PD 237-340 28 3.3e-12 38.0 In-house 131-220 (229) Show / Hide 
Range on Protein: 237-340
Range on HMM: 131-220/229
Sequence Identity: 28% (30 aa)

KTRKIYHFQYtTWPDHGTPvSTTGFLKFVSFVDHEKRSGPIVVHCSAGIGRSGTFVAIHSIvakFAKHYDEKKqApsinlpklVVEMRNERPGMVQTRDQ
. ..||.... ...|.|.. | .  |  |  ||   . | | ||| || || |  .| . .   .||... .. |        .  .|..||  .|||.|
mrqgiyfynf-glkDygva-sleriLdivkvvdfaleegkiavHCHAGlGRtGvliacylv---yakrltaee-a--------iklvrskrpksiqtreq

YRFC
 ...
velv
Phosphatase ptpB.AA Subfamily.DSP23.PD 257-338 25 5e-09 28.0 In-house 48-118 (128) Show / Hide 
Range on Protein: 257-338
Range on HMM: 48-118/128
Sequence Identity: 25% (21 aa)

STTGFLKFVSFVDH-EKRSGPIVVHCSAGIGRSGTFVAIHSIVAkfakhydEKKQAPsinlpKLVVEMRNERPGMVQTRDQYR
.     ..|  |.  ||. ... |||  |.||.||..| . .         |.  |      . ..|.|..|.| ..|..| .
aleqvarlvriveeaekkeeavgvhcalGlGrtGtllacylvke-------eglaad-----daiaevrkrrkGsietveqek
Phosphatase ptpB.AA Subfamily.R_Anemone_2.PD 44-86 41 6.8e-09 27.3 In-house 14-57 (262) Show / Hide 
Range on Protein: 44-86
Range on HMM: 14-57/262
Sequence Identity: 41% (18 aa)

E-TDKFRSALEAKNKLKNRYSNVLPFEETRVKINIDDDDDDEDD
| . ...||||  || ||||.|.|....||||..  ... . | 
etsvtlksalepvnkaknryanilaydktrvklqmlegeegsdy
Phosphatase ptpB.AA Subfamily.CDC14.PD 261-333 30 6.7e-08 24.1 In-house 187-245 (258) Show / Hide 
Range on Protein: 261-333
Range on HMM: 187-245/258
Sequence Identity: 30% (22 aa)

FLKFVSFVDHEkrSGPIVVHCSAGIGRSGTFVAIHSIvakfaKHYDekkqapsINLPKLVVEMRNERPGMVQT
||.. ...   .| |.||| ||.|| ||... . |     |||        .. .  .  .|  |||.| .  
lkkfleiteka--eGaiavhCkaGLGrtgtligcyli-----khyr-------ftaaetiawlriarPGsvig
Phosphatase ptpB.AA Subfamily.N12.PD 29-92 23 1.6e-07 22.4 In-house 4-68 (270) Show / Hide 
Range on Protein: 29-92
Range on HMM: 4-68/270
Sequence Identity: 23% (15 aa)

KEFNFILQKT-ELRALETDKFRSALEAKNKLKNRYSNVLPFEETRVKINIDDDDDDEDDNEDDII
|||. . . . ...| .. .  .. . .|. |||| ..||....||... .......|    ..|
kefqklkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdyinanfi
Phosphatase ptpB.AA Subfamily.PTPMT1.PD 231-297 26 2.7e-07 22.2 In-house 43-109 (146) Show / Hide 
Range on Protein: 231-297
Range on HMM: 43-109/146
Sequence Identity: 26% (18 aa)

ENLKDNKTRKIYHFQYTTWpDHGTPVSTTGFLKFVSFVDHEKRSGP-IVVHCSAGIGRSGTFVAIHSI
.. .. |   . ..|..|. |..   |.    . |.|.....  |  . ||| || .||.| || . .
nsteewkklGveqlqlatv-DfteapslekleegvefiekvaskgssvYvHCkAGrtRsatlvacylm
Phosphatase ptpB.AA Subfamily.N13.PD 41-76 48 3.2e-07 21.7 In-house 10-46 (259) Show / Hide 
Range on Protein: 41-76
Range on HMM: 10-46/259
Sequence Identity: 48% (18 aa)

RAL-ETDKFRSALEAKNKLKNRYSNVLPFEETRVKIN
| |  .|. ... ...|| |||| ||||..|||||..
relkpldtcevgkkkenkdknryrnvlPydetrvklg
Phosphatase ptpB.AA Subfamily.DSP19.PD 261-301 26 4e-07 21.6 In-house 65-105 (139) Show / Hide 
Range on Protein: 261-301
Range on HMM: 65-105/139
Sequence Identity: 26% (11 aa)

FLKFVSFVDHEKRS-GPIVVHCSAGIGRSGTFVaIHSIVAKF
. . . |... ... | ..|||.||. || ..| |  .... 
lkealdFieearskdgrvlvHCnAGvSRsasvv-iaylmkde
Phosphatase ptpB.AA Subfamily.DSP1.PD 235-297 26 4.2e-07 21.7 In-house 39-102 (139) Show / Hide 
Range on Protein: 235-297
Range on HMM: 39-102/139
Sequence Identity: 26% (17 aa)

DNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSFVDHEK-RSGPIVVHCSAGIGRSGTFVAIHSI
.|. .......  .  |. .   .. | . . |.|. | . | ..||| ||| || |.| .. .
pnvfeelfkyksipvednkkadisslfeeaidfidsvkkkgGrvlvhCqaGisrsativlayLm
Phosphatase ptpB.AA Subfamily.RG.PD 28-85 25 4.3e-07 21.3 In-house 3-56 (264) Show / Hide 
Range on Protein: 28-85
Range on HMM: 3-56/264
Sequence Identity: 25% (15 aa)

DKEFNFILQKtELRALetdKFRSALEAKNKLKNRYSNVLPFEETRVKINIDDDDDDED
...|. | .  . . .   .  |. . .|| |||..|....|..|||..   . |..|
eeqfeeiqkl-kpkdi---eaesskkeenkeknReinivaversRvklsplpgkdgkD
Phosphatase ptpB.AA Subfamily.RB.PD 44-90 37 7.5e-07 20.4 In-house 13-60 (261) Show / Hide 
Range on Protein: 44-90
Range on HMM: 13-60/261
Sequence Identity: 37% (16 aa)

E-TDKFRSALEAKNKLKNRYSNVLPFEETRVKINIDDDDDDEDDNEDD
. ... ..| ||.|. |||..|.||....|||..  .|..|.|     
gkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinan
Phosphatase ptpB.AA Subfamily.LRR-DSP.PD 261-294 37 2.1e-06 19.3 In-house 64-97 (137) Show / Hide 
Range on Protein: 261-294
Range on HMM: 64-97/137
Sequence Identity: 37% (12 aa)

FLKFVSFVDHEKRSGPIVVHCSAGIGRSGTFVAI
| .  .|.|. ...| ...|| ||. || | |  
fkemnafidegrekggvlihcragvsrsatlvia
Phosphatase ptpB.AA Subfamily.N9.PD 46-85 41 4.2e-06 18.0 In-house 16-55 (275) Show / Hide 
Range on Protein: 46-85
Range on HMM: 16-55/275
Sequence Identity: 41% (16 aa)

DKFRSALEAKNKLKNRYSNVLPFEETRVKINIDDDDDDED
.|  .    |  ||||..|| ..|||||..  |.|.  | 
Gtflasklranleknrytdvlcydetrvklakldedeasd
Phosphatase ptpB.AA Subfamily.R_Sponge_2.PD 46-82 30 6e-06 17.5 In-house 15-51 (262) Show / Hide 
Range on Protein: 46-82
Range on HMM: 15-51/262
Sequence Identity: 30% (11 aa)

DKFRSALEAKNKLKNRYSNVLPFEETRVKINIDDDDD
..  |   .|. |||....||....||... |.  | 
fslsiaklkenvgKnRfkeilpydmsRvrLrtdgskd
Phosphatase ptpB.AA Subfamily.PTEN.PD 245-307 28 9.4e-06 16.8 In-house 68-127 (305) Show / Hide 
Range on Protein: 245-307
Range on HMM: 68-127/305
Sequence Identity: 28% (19 aa)

QyttwpDHGTPvSTTGFLKFVSFVD---HEKRSGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYDE
.     ||  | .     ..|. ||   .| .|  ..||| || ||.|. .. . .  .  |. ||
d-----Dhnpp-tleLleeivedvdkwLkedksnVvavHCkaGkGRtGvmicayLlksgikksade
Sequence
Name Sequence Type Origin Length Description Download
ptpB.AA Protein None 377 None Fasta, JSON
ptpB.NA RNA None 1134 None Fasta, JSON
ptpB.AA.PD_26-349 Protein Phosphatase Domain None 324 None Fasta, JSON