ptpC
Species: D.discoideum
Alias: DDB_G0282145, ptpC
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Protein domain

Protein domains of ptpC.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ptpC.AA Dicty3 162-262 31 4e-06 15.91 In-house 206-260 (351) Show / Hide
Range on Protein: 162-262
Range on HMM: 206-260/351
Sequence Identity: 31% (32 aa)

NNNNNNNNNNNNNNNNNNNNNNNNNNSNSNIEIN-VPSIQFDNEPAMEVDSVAPLNVPSNHTRTTLAMHNTKSLSTSNIGLLNILPNQQSSSSSSLSSTT
|||||||||||||||||||||||||. | .  || .                                               |. |.|..... ..  |
NNNNNNNNNNNNNNNNNNNNNNNNNTNNNVKIINNN-----------------------------------------------IYSNKQYKQKCYSICGT

TT
..
IH

Phosphatase ptpC.AA Subfamily.N23.PD 319-712 26 3.5e-46 149.0 In-house 44-345 (350) Show / Hide
Range on Protein: 319-712
Range on HMM: 44-345/350
Sequence Identity: 26% (84 aa)

QQQMQQH--QQHQYKKANLSSLSTVVDNnlnnnpmntstSSPAQPNASPFSfsssslfsnsslsnsgsgsasttststsssnsmssspppslktsfsqld
.....   |... ..  ..|   ....           . . .|.  |.|   .         || .  |...  .   ....|| |   .  .   |||
wseledyqgqeaiaadqsiasakrmsnk-----------nrqfnpdllpyh-------------------------------------------------

edrekmrlefemikkpemaskkshkhhqrhyshndLDNRKHDEEKFFSALQPNNYGKNRYHDVLPNESTRVRLT--PIESGDGDYINANYINGEVPNSYR
|| |.   .| |   .|| |.|..||. ||| ||||..|||||.||| .|..|.| | |.|.   ... .| . . |...   .      |||..  .  
-----------------------------------lqpttitavpqprhlqtegsGqqqgtpdsrhdpnrvklqqstqpgqqddyinatylkeltpmsPp

yYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEENGKKKADVYYPET-SQAQEYGSFWIHLHKKVMFKDIGVSSLHLYKKGEEFPREVVLLHYTQWPD
|.|. ||.|.|.. |.| | ...  .   |.|  |.      . . . |.|.|||||.||.|||  .   .....   ..   .| . | .||.||. ||
-fiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslkslrssegwiervlhlqhndvstvrlvchlhtttWse

CGAPPSSSHIRTLSVMVNTFKARGS----AKNTNGPVIVHCSAGIGRSGTFISININMAKIErfgNDPSQMniSIKDSVLELRRQRRGMVQTLDQYIFIF
|. ... ......                                                                                       
iGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysairelt---agngii--niprvvrrlrqqRkymvqkkvilkkly

KVI
   
eav

Phosphatase ptpC.AA PTPc 444-717 29 1.7e-108 367.67 SMART 1-308 (308) Show / Hide
Range on Protein: 444-717
Range on HMM: 1-308/308
Sequence Identity: 29% (94 aa)

QRHYSHNDLDNRKHDEE--------KFFSALQPNNY--GKNRYH-DVLPNESTRVRLTPIES-----GDGDYINANYINGEVPNSYRYYIACQAPLPSTI
.    ...|.. . . .        .. .|  |.|    ||||  |......|||.|.|...     ...||||||||.|.  .... ||..|.|||.||
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY--WRPKRYICTQGPLPHTI

KDFWRMVWEERSSVIVCLTKLEEN--------GKKKADVYYPETSQAQEYGSFWIHLHKKVMFK-DIGVSSLHLYKKGE--------EFPREVVLLHYTQ
 |||||||......||.|....|.        |..| . |.|..   ..|| ..... ...  . |. .  . . ..|.        . .|.|  .||| 
EDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE--PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTN

WPDCGAPPSSSHIRTLSVMVNTFKARG--------------SAKNTNGPVIVHCSAGIGRSGTFISININMAKIERFGNDPSQMNISIKDSVLELRRQRR
|||.|.|.|....  .  .|.. ...               ...  .||..||||||.||.|||..| | . .||.         ..|.. | ..| || 
WPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---------VDIFQIVKMMRNQRP

GMVQTLDQYIFIFKVINDVLT
|||||..||||. ..| ... 
GMVQTEEQYIFCYRCILEYIK

Phosphatase ptpC.AA Y_phosphatase 470-714 37 1.6e-104 358.35 Pfam 1-243 (243) Show / Hide
Range on Protein: 470-714
Range on HMM: 1-243/243
Sequence Identity: 37% (96 aa)

NYGKNRYHDVLPNESTRVRLTPI-ESGDGDYINANYINGEVP-NSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEENGK-KK-ADVYYPE--T
|  |||| |......|||.|.|| . .|.||||||||.|  | .. . ||..|.|.|.||.|||||||......||.|....|.|. .|  . |.|.   
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDG--PYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKE

SQAQEYGSFWIHLHKKVMFKDIGVSSLHLYKKGE--EFPREVVLLHYTQWPDCGAPPS-SSHIRTLSVMVNTFKARGSAKNTNG--PVIVHCSAGIGRSG
.| ..|| |.... .. . .|. |  ..... |.  . .|.|  .||| |||.|.|.| . ..  .  .|....     .. .|  |..||||||.||.|
GQPMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP----NPDHGCPPIVVHCSAGCGRTG

TFISININMAKIERFGNDPSQMNISIKDSVLELRRQRRGMVQTLDQYIFIFKVIND
||..| | . ..|. |        .|.. | ..|.|| |||||..||||. ..| .
TFCAIDIMCQQMEHEGTV------DIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

Phosphatase ptpC.AA Subfamily.RB.PD 459-716 39 1.8e-71 231.8 In-house 15-260 (261) Show / Hide
Range on Protein: 459-716
Range on HMM: 15-260/261
Sequence Identity: 39% (102 aa)

EEKFFSALQPNNYGKNRYHDVLPNESTRVRLTPIES-GDGDYINANYINGEvpNSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEENGKKKAD
...  .| .. |  |||.. .|| ...||.|. ...  | ||||||||.|   || | |||.| |||.|..||||||||..||.|| ||.| |.||.| .
dqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgy--nspreyiatqGPlpetvddfWrmvwekkssiivmltqlvEkgkekce

VYYPETSQAQEYGSFWIHLHKKVMFKDIGVSSLHLYKkGEEfPREVVLLHYTQWPDCGAPPSSShirTLSVMVNTFKARGSAKNTNGPVIVHCSAGIGRS
 |.|...... ||.  ..| ..   ..  . .... | |.|  |.|  .|.| ||| | | ...   ||  .|.|.. . ..| ...|..||||||.||.
eYWPadeepvlyGdikvtllaekeldewvirefkiek-gke-krkvrqyhftsWpdhgvPektk---tlldfvrtvreaiekkaskkPivvHCsaGvGRt

GTFISININMAKIERfgndpsQMNISIKDSVLELRRQRRGMVQTLDQYIFIFKVINDVL
||||...  . .||.      .  . .   | |||..|  .|||..|||||.... |.|
Gtfialdrllqaiee------ndyvdvfgvvaelReeRnllvqtekqyifiheclldll

Phosphatase ptpC.AA Subfamily.R_Anemone_2.PD 452-716 40 2.1e-71 231.7 In-house 9-261 (262) Show / Hide
Range on Protein: 452-716
Range on HMM: 9-261/262
Sequence Identity: 40% (108 aa)

LDNRKHDEEKFFSALQPNNYGKNRYHDVLPNESTRVRLTPIESG-DGDYINANYINGEvpNSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEE
|.. ..   .. |||.| |  |||| ..|. ..|||.|...|.  . ||||||||.|   .. . |||.||||| ||.||||||||  |.||| ||..||
lsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGy--rrkkayiatqaPlpetiedfWrmvWeqnsavivmltqeee

NGKKKADVYYPEtSQAQEYGSFWIHLHKKVMFKDIGVSSLHLYKKGEEFPREVVLLHYTQWPDCGAPPSSSHIrtLSvMVNTFKaRGSAKNTNGPVIVHC
.||.| . |.|. .....||.  ..|...| ..|  . |... ...||  |.|   |||.||| |.| |....  |. .|.. . .  .....||..|||
rgkakvhryWPs-kgsrsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgasl--ld-lvrqve-kaqqesgagpivvhc

SAGIGRSGTFISININMAKIERfgndpsQMNISIKDSVLELRRQRRGMVQTLDQYIFIFKVINDVL
|||.|| |.|| ..| . .|.       .  . . . | .||.||  |||| |||.||..|. . |
saGvGrtGvfiavdillerika------ealvdvfqtvkqlreqrnlmvqtkdqyefiydvlleal

Phosphatase ptpC.AA Subfamily.R_Sponge_2.PD 451-716 35 4.3e-68 220.8 In-house 6-261 (262) Show / Hide
Range on Protein: 451-716
Range on HMM: 6-261/262
Sequence Identity: 35% (94 aa)

DLDNRKHDEEKFFSALQPNNYGKNRYHDVLPNESTRVRLTPIESGDGDYINANYINGEvpNSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEE
. . .|..| ..  | ...| ||||....|| ...||||.. .| |.|||||....|   ..   ||| |.||..|..||||||||..| || ||.||||
eksveketefslsiaklkenvgKnRfkeilpydmsRvrLrtdgskdsDYinAsfvdgy--krrkayiatqgPlketveDfWRmvweykvstivmltnlee

NGKKKADVYYPET-SQAQEYGSFWIHLHKKVMFKDIGVSSLHLYK-KGEEFPREVVLLHYTQWPDCGAPPSSSHIRTLSVMVNtfkaRGSAKNTNGPVIV
||.|.  |.||.  ...|||.| . |...  ..|  .  |.| | |..|  ..|   |...||. . | ... .  |   |.    |   |. |....|.
ngkekcakYWPekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvl----raqkksgnkaitv

HCSAGIGRSGTFISININMAKIERfgndpsQMNISIKDSVLELRRQRRGMVQTLDQYIFIFKVINDVL
||.|.||.|||| ... . ...         .| . . . .|| .| |.||. .|||| .......  
vCsdgvgrtGtfialdsvlerlka------eeeidvfevlktlrtkriglvqdaaqYvfihdalleyi

Phosphatase ptpC.AA Subfamily.N12.PD 463-715 36 1.4e-65 212.3 In-house 25-268 (270) Show / Hide
Range on Protein: 463-715
Range on HMM: 25-268/270
Sequence Identity: 36% (92 aa)

FSALQPNNYGKNRYHDVLPNESTRVRLTPIESGD-GDYINANYINGevPNSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEENGKKKADVYYP
.. ...|. ||||.|.|| . .|| |. ||. .  ||||||.|.|  ...   |||.|.|||.|..|||||.|| . ...| . .. |.|||| . |.||
eagekeenvkknrykDilPydksrvelskieeeegsdyinanfikg--vegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryWp

ETSQAQE-YGSFWIHLHKKVMFK-DIGVSSLHLYKKGEEfpREVVLLHYTQWPDCGAPPSSSHIRTLSVMVNTFKArgsakNTNGPVIVHCSAGIGRSGT
. . .  .|.| . |... ... |. . .|.. ...|.  |.|  .|||.||| | | | ...  |  .|....      . . |..||||||.|| || 
eegeeelefgefevtleeekavdddflirtLkveaqkes--rkvyqfhytaWPDhgvPssaksllelielvrelqe-----sedaPlvvhCsaGvGrtGt

FISININMAKIERfGNDPSqmNISIKDSVLELRRQRRGMVQTLDQYIFIFKVINDV
|.|..    ... .. |.  .... | |||||.||  .||| .|| ...| . .. 
iiaidyvrellka-ekipe--eldvfdlvlelrkqraalvqtkeqyelvykavael

Phosphatase ptpC.AA Subfamily.N5_RR.PD 470-713 38 6.1e-65 210.4 In-house 23-261 (265) Show / Hide
Range on Protein: 470-713
Range on HMM: 23-261/265
Sequence Identity: 38% (95 aa)

NYGKNRYHDVLPNESTRVRLTPIES--GDGDYINANYINGEVpNSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEENGKKKADVYYPETSQA-
.  ||||...|||| .|| |.. .|   | .||||||| |   .  . |.| | |||.||.|||||...|...||| ||||.|. ..|  ||.|.. .. 
sqtknryktilPnensrvllesessededssyinanyikGyd-eeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdaedye

--QEYGSFWIHLHKKVMFKDIGVSSLHLyKKGEEFPREVVLLHYTQWPDCGAPPSSSHIrtLSVMVNTFKARGSAKNTNGPVIVHCSAGIGRSGTFISIN
  ..|| . |. ...|  .|  | .| | |. |. .|.|.   ||.|||  .| . ...  |... .. ..| ....  .||.||||||||| | ||.|.
iserygdveikveeiverndysvrklvl-kylerversvkhywytdWPdhksPddintl--ldlvleveesreeenaklaPvvvhcsaGiGrtGcfiais

INMAKIERfgndpsQMNISIKDSVLELRRQRRGMVQTLDQYIFIFKVIN
| . ....      .. . .   | .|| .| ||||| .|| .|.... 
iavrqlre------eivvdvlkivcnlrldrGGmvqtseqyelihralc

Phosphatase ptpC.AA Subfamily.N3.PD 455-713 39 2.2e-64 208.4 In-house 11-257 (261) Show / Hide
Range on Protein: 455-713
Range on HMM: 11-257/261
Sequence Identity: 39% (101 aa)

RKHDEEKFFSALQPNNYGKNRYHDVLPNESTRVRLTPIESgdgDYINANYINGEVPNSY--RYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEENG
||...     | .|.|  ||||.|.|| ..|||.|.  |.   |||||||.| |.| .     |||.| ||..| ||||.||||..|..|| ||| |.|.
rkkpglaisaarkpenlaknryrdilpydatrvklkeset---dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverG

KKKADVYYPETSQAQEYGSFWIHLHKKVMFKDIGVSSLHLYKKGEEFPREVVLLHYTQWPDCGAPPSSSHIRTLSVMVNTFKargsaKNTNGPVIVHCSA
.|   |.|||.. .|.|.| ....|.   | . .  | | .| ..  |... | |..||| | | .|... ..   |.. .     ... ||.|||||||
rvkChqyWPetedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklr-----sgkeePvvvhCsa

GIGRSGTFISININMAKIERfgndpsQMNISIKDSVLELRRQRRGMVQTLDQYIFIFKVIN
||.| .| ... .|.||.      . .. . | | ..| ||  .||| .|| |. . |   
GigrtGvlilletalaliea------aepvypldivrtmrdqramlvqtvsqykfvCeail

Phosphatase ptpC.AA Subfamily.N13.PD 466-716 39 3.3e-64 208.1 In-house 22-258 (259) Show / Hide
Range on Protein: 466-716
Range on HMM: 22-258/259
Sequence Identity: 39% (98 aa)

LQPNNYGKNRYHDVLPNESTRVRLTpiesGDGDYINANYINGEVPNSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEENGKKKADVYYPETSQ
. .|  ||||..||| . |||.|     ..| ||||..|. .| .    ||||| ||| |.||||.|||| ...||. .|.  |.|| | .|.||. .  
kkkenkdknryrnvlPydetrvklg----deggyinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPerkn

A--QEYGSFWIHLHKKVMFKDIGVSSLHLYKKGEEFPREVVLLHYTQWPDCGAPPSSSHIRTLSVMVNTFKargsakNTNGPVIVHCSAGIGRSGTFISI
 . .. . ..| | .  ..  |..|.. ..  .  |||. |....||| | | |. .. ..   |....      . .||..|||||||||||..|.|..
kklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllq------tdagPivvhcsaGiGrsGvliti

NINMAKIERFGndpsqmNISIKDSVLELRRQRRGMVQTLDQYIFIFKVINDVL
 .  |||        .. .|. | .||.||.|.||| |||||..|.| .||  
dvvlglierdk------efdvkeivrklreqrqgvvqtkdqyifvykailevl

Phosphatase ptpC.AA Subfamily.R_Anemone_1.PD 456-716 38 6.4e-64 207.3 In-house 11-257 (258) Show / Hide
Range on Protein: 456-716
Range on HMM: 11-257/258
Sequence Identity: 38% (99 aa)

KHDEEKFFSALQPNNYGKNRYHDVLPNESTRVRLTPIES-GDGDYINANYINGEVPNsyRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEENGKK
...||.  .| ...|  ||||.|... ...|| |.  ..  ..||||| |...      | .||.||||..|..|||||||.|...||| || |.|. ||
eikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdkt--rafiatqapleetvedFWrmvwqekigviVmLtnliegekk

KADVYYPEtsQAQEYGSFWIHLHKKVMFKDIGVSSLHLYKKGEEFPREVVLLHYTQWPDCGAPPSSSHIRTLSVMVNTFkargsAKNTNGPVIVHCSAGI
|   |.|.  ....||.. ..|.||  | |. . .| | ||.|.  |||| .|.|.||| | |  .  .|   |..       .. . ||.||||||.||
kchqYwPd--stekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqks-----slagarpvvvhCsaGv

GRSGTFISINinmAKIERFGndpSQMNISIKDSVLELRRQRRGMVQTLDQYIFIFKVINDVL
.|.|. |.   | .|.     ..  . | . |  .|..|  |||| .||.||.... . |  
gRtGaflvid---amleqak---kekvvDifnyvkairedrphmvqtkeqyvfihlavleal

Phosphatase ptpC.AA Subfamily.RG.PD 452-715 33 1.1e-62 203.0 In-house 9-262 (264) Show / Hide
Range on Protein: 452-715
Range on HMM: 9-262/264
Sequence Identity: 33% (89 aa)

LDNRKHDEEKFFSALQPNNYGKNRYHDVLPNESTRVRLTPIESGDG-DYINANYINGEvpNSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEE
. . |... .  |. ...|  |||. .... |..||.|.|.   || |||||.||.|   .  . ||. | ||..||.|||||.||.....||||.|.|.
iqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGy--rrskeyivtqgplketiedFWrmiWehnaqiivmltdlde

NGKKKADVYYPETSQAQEYGSFWIHLHKKVMFKDIGVSSLHLYKKGEEFPRE--VVLLHYTQWPDCGAPPSsshirTLSVMVNTFKARGSAKNTNGPVIV
|... |||.|.  .. |.... . | .|  .... | .. | ..  .  .|  |  .|||.|||.|.| |     || |...  |.. |...||..||.|
kgrrdedvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPes-----tlfvlifvkkeeaankeeaGPivv

HCSAGIGRSGTFISININMAKIERfgndpsQMNISIKDSVLELRRQRRGMVQTLDQYIFIFKVINDV
|| ||.||.| ..  . ..|.      . .. . . .  .| .| |.|.| .||.||.... ..   
hdsaGvgragtyialdtllqqlek------eeavnvyqvlklirakRpglvtteEqyvfiydallel

Phosphatase ptpC.AA Subfamily.N6.PD 425-714 34 5.3e-62 200.9 In-house 17-292 (295) Show / Hide
Range on Protein: 425-714
Range on HMM: 17-292/295
Sequence Identity: 34% (105 aa)

EFEMIKKPEMASKKSHKHHQRhyshndldnrkhdeekffsalqPNNYGKNRYHDVLPNESTRVRLTPI-ESGDG-DYINANYI--------NGEVPNSY-
||| ..| |. ...|.|. ..                      ..|  ||||...|| . ||| |.   .|  | ||||||||        .||...|  
efeelqkqeseklysrkegek----------------------ienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenvesee

--RYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEENGKKKADVYYPETSQAQEYGSFWIHLHKKVMFKDIGVSSLHLYK-KGEEFPREVVLLHYTQ
  . ||| | .|..|..|||||||.| | ||| .||  | ||.|   |.|.... .|.|.  ..  .    .|  .  ... . . ..||.. .|...||
hqkryiatqgcLkdtvsdFWrmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfka

WPDCGAPPSSSHIRTLSVMVNTFKARGsakNTNGPVIVHCSAGIGRSGTFISININMAKIERFGNDpsqMNISIKDSVLELRRQRRGMVQTLDQYIFIFK
| | | ..... ..   ||. . .    ...||..||||||||| |||| |.| .  ||. | |   ..| |. |. ..|.|| |.||| .||.|..|..
WPdhgvpkdpgvvlnfledvnkkqeel---ekagpivvhcsaGiGrtGtfividivlkiieqsgld---vdidisksikdvrsqrsglvqteaqykfvyk

VIND
.   
avqf

Phosphatase ptpC.AA Subfamily.N_Choan_1.PD 465-716 35 3.5e-61 198.1 In-house 21-261 (262) Show / Hide
Range on Protein: 465-716
Range on HMM: 21-261/262
Sequence Identity: 35% (87 aa)

ALQPNNYGKNRYHDVLPNESTRVRLTPIE-SGDGDYINANYINGEvpNSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEENGKKKADVYYPET
. ...|  ||||...   . |||..|| | . . ||||||...|   .. . |||.|.|.|.....||.||||.. |.|| .|.  |.|| |   |.|. 
skadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgy--kgekeyiatqgPvPaslvsfWqmvweqkvsaivmvtreieagklkChryWPde

SQAQEYGSFWIHLHKKVMFKDIGVSSLHLYKKGEEfPREVVLLHYTQWPDCGAPPSSSHIRTLSVMVNTFKargsAKNTNGPVIVHCSAGIGRSGTFISI
... ..| . .. ... . |      ..|.... | .|||. |.||.||| |.| .....      |. ..|.|. |...|||||.||.||.|...  . 
nselklgdvtvkslseeekktyierkfkleresge-treveqlaytaWPdhGvPattkellefrkavlkat----kkktkaplvihCsaGvGrtGtyial

NINMAKIERfgndpSQMNISIKDSVLELRRQRRGMVQTLDQYIFIFKVINDVL
..|.     .. ....|. | |||..|  ||||| || |..|.. |.|     
Drlvkavee-----kaealdvkavvaelrkernlmvqtlvqyefvykavldal

Phosphatase ptpC.AA Subfamily.N14.PD 456-713 36 5.6e-60 194.0 In-house 12-271 (275) Show / Hide
Range on Protein: 456-713
Range on HMM: 12-271/275
Sequence Identity: 36% (97 aa)

KHDEEKFFSALQPNNYGKNRYHDVLPNESTRVRLTPIESGDGDYINANYINGEVPNSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEENGKKK
|. . .. .|  |.|  |||..|||| | .||.|.| .  . .||||  |.  |  . | ||..|.||. |..|||.||||.  ..|| ||.||.||.|.
kredallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlteeeedgkek

ADVYYPET---SQAQEYGSFWIHLHKKVMFKDIGVSSLHLYKKGEEFPREVVLLHYTQWPDCGAPPSSSHI----RTL-SVMVNTFKARGSAKNTNGPVI
  |.|..    .  |.| | .  . .   . .  ..|.|.    .  |.|. | || ||| | |.  ..     . . ||  .|. . |.|... ||.||
sfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvkeskPPvl

VHCSAGIGRSGTFISININMAKIERfgndpsQMNISIKDSVLELRRQRRGMVQTLDQYIFIFKVIN
||||.||.|  |  .. .| .|       . .| || ..  ||.||  .|||| || |..||.   
vhCsaGvGrtGvlilsdlliatleh------neeidikkvlarLrkqrmllvqtlaqykfvykvli

Phosphatase ptpC.AA Subfamily.RA.PD 450-715 33 3.1e-58 188.4 In-house 7-264 (266) Show / Hide
Range on Protein: 450-715
Range on HMM: 7-264/266
Sequence Identity: 33% (89 aa)

NDLDNRKHDEEKFFSALQPNNYGKNRYHDVLPNESTRVRLTPIES-GDGDYINANYINGEvpNSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKL
. | . |  .||.  | ...|  |||. ..||.. .|| |. .|   . ||||| .|.|   .   ..||.| |.  |..|||||.|| .|. || ||.|
kkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGy--rekdkfiaaqGpkeetvedfwrmiweqksativmltel

EENGKKKADVYYPETSqAQEYGSFWIHLHKKVMFKDIGVSSLHLYKKG----EEFPREVVLLHYTQWPDCGAPPSSSHIrtLSVMvNTFKARgSAKNTNG
.| ...|   |.|.   .  ||   ........ .|. |  . . ...    |. .| |  .|.| ||. | | ..  .  |... .|.    ...| |.
kerkeekcaqywpdeG-lvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGm--lkll-kkvkkl-qqqsanh

PVIVHCSAGIGRSGTFISININMAKIErfgndpSQMNISIKDSVLELRRQRRGMVQTLDQYIFIFKVINDV
.||||||.||.|||| ..  .....      ..  . . . | .|| ||  ||||| || ||.||. .   
pivvhcsaGvGrtGtfivldavlervk------aerkldvfeavkrlrlqrpqmvqtleqyefiykvlley

Phosphatase ptpC.AA Subfamily.N_Choan_2.PD 452-714 32 3.2e-58 188.2 In-house 5-263 (266) Show / Hide
Range on Protein: 452-714
Range on HMM: 5-263/266
Sequence Identity: 32% (87 aa)

LDNRKHDEEKFFSALQPNNYgkNRYHDVLPNESTRVRLTPIESGD-GDYINANYINGEVPNsYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEE
||... .||.  .. . ...  |||.|.||.  ||||| ..|. .   ||||||..|   .  ..||| ..|||.|.|.||||.|||... || .|.|||
ldkqevseeaiPeyarnkrl--nRyndiLPsPatRvrleeleedsataYinAnyvrGfdge-kkkYiaamgPlpttlksfwrmiweekvtaivmttgleE

NGKKKADVYYPETSQ-AQEYGSFWIHLHKKVMFKDIGVSSLHLYKKGEEFPREVVLLHYTQWPDCGAPPSSSH---IRTLSVMVNTFKARGSAKNTNGPV
.|.|| ..|.|. ..   .. .  |.  .    |. |    .|  . ..  |..|  .|..||| |.| .. .. |  |... ..  .  . ..|..|||
kgrkkCerYWpaepkekvkladgkikvlalseekeegyiltrlrlekkgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePl

IVHCSAGIGRSGTFISININMAKIERfgndpsQMNISIKDSVLELRRQRRGMVQTLDQYIFIFKVIND
|||.||.||.| |.| .  .|.      .... .   . |||..|  .||. .|| ...|.. .    
lvHcsaGvgRtGtliaiDiavrlLee------tkkvdvlaiieelRkdRmalvqhpeqyellykavve

Phosphatase ptpC.AA Subfamily.N9.PD 457-712 33 6.4e-58 187.6 In-house 13-270 (275) Show / Hide
Range on Protein: 457-712
Range on HMM: 13-270/275
Sequence Identity: 33% (88 aa)

HDEEKFFSALQPNNYGKNRYHDVLPNESTRVRLTPIESGD-GDYINANYINGEvpNSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEENGKKK
| .|  . .. |  ||||.|||  ..||| |. ..  .  ||||||...|   .  . .|| | ||. |..||||||||..  |||  |...|.|. |  
pveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGy--kqkkafiatqGplkktvsdfwrmvweqevlvivmttrvvergrlk

ADVYYP-ETSQAQEYGSFWIHLHKKVMFKDIGVSSLHLYKKGEEFPREVVLLHYTQWPDCGAPPSSSHIRT--------LSVMVNTFKARGSAKNTNGPV
 |.| |. ...|.|.. ..  .... .|  |..|....  .|  |.|.   .. ||| | | |.. .           ...|.....   . .. |..||
cgqywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdeskghlsgPPi

IVHCSAGIGRSGTFISININMAKIERFGndpsqmNISIKDSVLELRRQRRGMVQTLDQYIFIFKVI
|||||||.||||...|..|..|. |      .. ....|  || ||  ..|| .|| | .. .   
vvhcsaGiGrtGtfitldiclarleevg------tvdvvetvkllrtqrafsiqtpeqyefcylav

Phosphatase ptpC.AA Subfamily.R_Ecdysozoa.PD 452-715 31 3.1e-56 181.7 In-house 9-267 (269) Show / Hide
Range on Protein: 452-715
Range on HMM: 9-267/269
Sequence Identity: 31% (84 aa)

LDNRKHDEEKFFSALQPNNYGKNRYHDVLPNESTRVRLTPIES-GDGDYINANYINGEvpNSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEE
|..| . . .   . . .|  ||||.|. . ..|||.|..|.   | |||||..|.|   .  . .|| |.|. .||.|||||..|  . .|| |..|.|
LearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgy--kekkkfiaaqdPveatigDfWrmiaeqevtlivmlsnlte

NGKKkADVYYPETsQAQEYGSFWIHLHKKVMFKDIGVSSLHLYKKG---EEFPREVVLLHYTQWP-DCGAPPSSSHIRTLSVMVNTFKARGSAKNTNGPV
. .|  . |.|.  . ..||.  ..| .. . .|    .|.. ||.   .|  |.||  .||.|. |  .| ..  .  |  .|. ..   .   ...|.
knrk-cakyWpie-devqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgsrsPi

IVHCSAGIGRSGTFISININMAKIERfgndpsQMNISIKDSVLELRRQRRGMVQTLDQYIFIFKVINDV
.|||||| ||||.|..... . ...         ...| . | .||.||  .|||.||.|... . |  
vvhCsaGvgrsgifvaldlllqqlka------edkvdifetvkkLrsqrnllvqsleqyvflyralady

Phosphatase ptpC.AA Subfamily.RK.PD 457-715 33 4.5e-56 181.1 In-house 16-265 (267) Show / Hide
Range on Protein: 457-715
Range on HMM: 16-265/267
Sequence Identity: 33% (86 aa)

HDEEKFFSALQPNNYGKNRYHDVLPNESTRVRLTPIESGDGDYINANYINGEvpNSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKL-EENGKKK
. |.. .|....|  |||. |.|. . ..|.|....  . |||||..|..   .  . .|. | ||..|.|||||.|..|... || ||.||.|. |   
lqsedcdiakkdrnreknrsmdilaydrslvflisvdgdssdyinaalidsy--krpaafivtqgPlqetvkdfWrlvydencasivmlteldvevgrvk

ADVYYPETSQaQEYGSFWIHLHKKVMFKDIGVSSLHLYK--KGEEFPREVVLLHYTQWPDC-GAPPSSshiRTLSVMVNTFKARGSAkNTNGPVIVHCSA
|.|| .. ..|| . ..| .  . .|. |  ....|  .| |  |||  .....||.  . | |    |.|  ..   |.  ....|...|||.|| |||
ClkyWPedte-vrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvsk---rsllklirrvkksqee-eeeGrivvhCla

GIGRSGTFISININMAKIERfgndpsQMNISIKDSVLELRRQRRGMVQTLDQYIFIFKVINDV
|||| |.| .  |||      .  . .   | .|| ..  ||.| .||.|.. || .      
GaGrsGtfiaidivlemier------egvvdvfnavktlrnrkvnmveteeqykfvydvilea

Phosphatase ptpC.AA Subfamily.N1.PD 460-710 35 4.3e-51 165.1 In-house 18-261 (268) Show / Hide
Range on Protein: 460-710
Range on HMM: 18-261/268
Sequence Identity: 35% (88 aa)

EKFFSALQPNNYGKNRYHDVLPNESTRVRLtpiESGDGDYINANYIngEVPNSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEENGKKKADVY
.  .| .|.| |.||| || | . .|..|   |..| |||||. .  |...  | ||  | ||| |.. ||.||||. |  .. | |. |...|   |.|
letreaklpenrglnryrdvspydhsrikl---eradvdyinaslv--eleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqy

YPETSQAQ--EYGS--FWIHLHKKVMFKDIGVSSLHLYKKGEEFPREVVLLHYTQWPDCGAPPSSSHIrtLSVmVNTFKARGSAKNTNGPVIVHCSAGIG
. ....  .. .  . ..| .. . .   |. |.|  . ..  ||..  |||.||| | | | . .  |.. . . .  || ..||...|||||||||||
wpqeeeeaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaaf--Lkf-LfkvresgsLssdvgpavihCsagig

RSGTFISININMAKIERFGNDPSqmnISIKDSVLELRRQRRGMVQTLDQYIFIFK
.  ..  ...||. |.  .   . ||. .||||..| |..|| ||  | .     
rsgtlslvdtclveiektgdlna---vdikkvLlelRkyRvGLiqtpdqLrFsyi

Phosphatase ptpC.AA Subfamily.RN.PD 452-712 35 2.3e-47 152.6 In-house 9-259 (264) Show / Hide
Range on Protein: 452-712
Range on HMM: 9-259/264
Sequence Identity: 35% (90 aa)

LDNRKHDEEKFFSALQPNNYGKNRYHDVLPNESTRVRLTPIESG-DGDYINANYINGEVPNSyRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEE
| . . ...    | ...|  |||...||| . .||.|.   |  . |||||  |  . | .   |||.|.||.||| |||.||||. . |||||.|||.
lcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdpra-payiatqgplsstiadfwqmvweqGvvvivnltrlee

NGKKKADVYYPETSqAQEYGSFWIHLHK-KVMFKDIGVSSLHLYKKGEEFPREVVLLHYTQWPDCGAPPSSSHIRTLSVMVNTfKARGsaknTNGPVIVH
| |. . |.|..  .. |. . .||   ..  .|  | |..|     .  | |  .|.  ||. |.|.|.  .  .   ||    |||..||||.| ||.
egvkqckrywpdeG-sevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnk-syrG----rscpivvh

CSAGIGRSGTFISININMAKIERfgndpSQMNISIKDSVLELRRQRRGMVQTLDQYIFIFKVI
|..| |.. .... .        .| |  ..  || || |.|.| ||. |.....        
csdGaGrtGvyilidlvlerllk-----Gvkeidiaatlehlrdqrpglvktkdqfefaltav

Phosphatase ptpC.AA Subfamily.N20.PD 460-716 37 5.3e-45 145.2 In-house 16-256 (257) Show / Hide
Range on Protein: 460-716
Range on HMM: 16-256/257
Sequence Identity: 37% (95 aa)

EKFFSALQPNNYGKNRYHDVLPNESTRVRLTpiesGDGDYINANYINGEVPNSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEENGKKKADVY
.| |  ||.|  ||||.|.|| .|||| |        |||||.||         .||| | || ||| |||.|| |. | ||  .|.  | ||.  |.| 
gefnsgnqpsnreknryrdilpydstrvplg----kskdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhy

YPET-SQAQEYGSFWIHLHKKVMFKDIGVSSLHLYKKGEEFPREVVLLHYTQWPDCGAPPSSShirtlSVMVNTFKARGSakNTNGPVIVHCSAGIGRSG
.  .  |   | . | .  ... . .  ... .|     . |  |..|.||| |.| |.      |..     || |     ||..|||||||||.| |.
wpislkkplelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasad-----sfikyiryarks--hltgpmvvhcsagigrtg

TFISININMAKIERfgndpsQMNISIKDSVLELRRQRRGMVQTLDQYIFIFKVINDVL
 ... .. | .      . .. | | | ..| || ||||| .|| | . .. .||   
vflcvdvvfcaivk------ncsfnimdivaqmreqrsgmvqtkeqyhfcydivlevl

Phosphatase ptpC.AA Subfamily.N_Nematode_4.PD 467-715 33 5e-44 141.8 In-house 23-262 (264) Show / Hide
Range on Protein: 467-715
Range on HMM: 23-262/264
Sequence Identity: 33% (83 aa)

QPNNYGKNRYHDVLPNESTRVRLTPiESGDGDYINANYINgeVPNSYRyYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEENGKKKADVYYPETSQA
. .|  ||||.|.|  . ||| |    . | ||| |...   .|. .| ||..| ||. |..||| ||..|. .|.| | .|.|.| .|   ||||.|. 
seknsdknryadilcidetrvvlkn-rdpdndyihaswmr--mPdkfr-yistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypeksek

-QEYGSFWIHLH-KKVM-FKDIGVSSLHLYKKG--EEFPREVVL---LHYTQWPDCGAPPSSShirtlsVMVNTFKARGSaKNTNGPVIVHCSAGIGRSG
 ...|.. |.|  ||.. . |. . ||.. .     . | | ..   .....|.|  ||  .... .||    |. ..|..||||||.||. |.. |.. 
vvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaa------pviklykavkk-kkkekPivvhcsaGvGrta

TFISININMAKIERFGndpsqmNISIKDSVLELRRQRRGMVQTLDQYIFIFKVINDV
  .|   .      .| . | | |||  | . ||.  |..|..|. .          
tlvGidyatirirens------eievldivrelramrlkavqshlqflfllvvliel

Phosphatase ptpC.AA Subfamily.N_Nematode_1.PD 458-712 34 4.2e-43 138.7 In-house 16-260 (265) Show / Hide
Range on Protein: 458-712
Range on HMM: 16-260/265
Sequence Identity: 34% (90 aa)

DEEKFFSALQPNNygKNRYHDVLPNESTRVRLTPiESGDGDYINANYINgeVPNSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEENGKKKAD
.. | |.. | ..  ||||.||   . .||.|.  |.   ||| |||.   .|   . .| .|||| .||.||| ||  |.|| | || |.||||   |.
ekvkafkeaqead--knrykdvgcldknrvklae-eplpsdyihanyvg--tptnpkrficaqaPldktiadfwymvlqekveaivmlckliekgkkkca

VYYPETS-QAQEYGSF--WIHL----HKKVMFKD---IGVSSLHLYKKGEEFpREVVLLHYTQWPDCGAPPSSSHIRtlsvmvntfKARGSAKNTNGPVI
| .. . .|. .    | .    . | . .|   | |  |..   ||.  |.|  ...|.||| |.||    .          .   .... .||..|||
eyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGekt-rkvthyqWtdWPdrGvPpadlaal---------elleavrgskgPiv

VHCSAGIGRSGTFISININMAKIERfGNDPSQMnisiKDSVLELRRQRRGMVQTLDQYIFIFKVI
||||||.|| ..|.  . |.   |.  ..|    .. | ..| ||.  .||  ||.|. .|.   
vhCsaGiGrtGtivaieyildklle-gkqiedm----eklvkkireqrnysiqtdaqylfvhrvl

Phosphatase ptpC.AA Subfamily.RC.PD 465-714 29 9.3e-43 137.7 In-house 21-285 (288) Show / Hide
Range on Protein: 465-714
Range on HMM: 21-285/288
Sequence Identity: 29% (81 aa)

ALQPNNYGKNRYHDVLPNESTRVRL-------------------TPIESGDG-DYINANYINGEvpNSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVC
| ...|  |||| |||| .  || |                     |.| .| .|||| .|..      . ||| | ||  |. |||||..|..||| ||
arkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsy--kkpekyiaaqGplketvddfwrmiferkvkvivm

LTKLEENGKKKADVYYPETSQAqeYGSFWIHLHKKVMFKDIGVSSLHLYKKGEEFPREVVLLHYTQWPDCGAPPSSSHIRTL-SVMVNTF----KARGSA
.|.|  ..|   |. |  .|  ||   ..|...    |  .  |.| .| .   |||. . ||.|.. . |     .  |  |. ..    .. .  .  
ltelkeGdrekcaeyweeGkra--yGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkrsseafk

KNTNGPVIVHCSAGIGRSGTFISININMAKIErfgndpSQMNISIKDSVLELRRQRRGMVQTLDQYIFIFKVIND
 .|..|||..| .|.|.||...  .  .|      ..  . . . | .||..| .||.. .|||....|. .   
nfkstpllvhcrdGsqrtGifiallallesle------aeekvdvfqvvkklrkarplmvsveeqyillydvlve

Phosphatase ptpC.AA Subfamily.R_Nematode_2.PD 464-708 32 1.6e-38 123.6 In-house 23-252 (261) Show / Hide
Range on Protein: 464-708
Range on HMM: 23-252/261
Sequence Identity: 32% (77 aa)

SALQPNNYGKNRYHDVLPNESTRVRLtpIESGDGDYINANYINGevPNSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEENGKKKADVYYP-E
. ..  .  |.||.||  ...|.|.   |  |    | ||...   ..  . .|| |.||  | .||| ||  |    || |..|. |.| . |.| |||
esaaylpkdkhRypdvPCkpetavev--ivdgkrvpihanwvpt--agnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfple

TSQAQEYGSFWIHL--HKKVMFKDIGVSSLHLYKKGEEFP-REVVLLHYTQWPDCGAPPSSshirtlsvmVNTFKARGSAKNTNGPVIVHCSAGIGRSGT
|  . | | |.   ..|.. ..| . .|.  ..  .|. | |  . |..||| | | |...|.    .|. . |..|||||||||...||...    ..|
tsqkldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPksh---------aelfeLlelvkksekPivvhCsaGiGRtma

FISININMAKIERfgnDPsqmNISIKDSVLELRRQRRGMVQTLDQYIFI
    ||   .|.... . ||| .|   .||  |. ..            
figteylarevea---dp---tieltealkelrehRwkgiqtesqlywl

Phosphatase ptpC.AA PTPc_motif 602-714 33 8.5e-38 132.8 SMART 1-92 (92) Show / Hide
Range on Protein: 602-714
Range on HMM: 1-92/92
Sequence Identity: 33% (40 aa)

EVVLLHYTQWPDC-----GAPPSSSHIRTLSVMVNTFKARGSAKNTNGPVIVHCSAGIGRSGTFISININMAKIERFGNDPSQMNISIKDSVLELRRQRR
.|  .|||.|||.     |.|  .| .. .  . .             |..||||||.||.|||..| . | .            ..|.. | |.| ||.
TVHHYHYTNWPDHVEKDSGVPE-DSILEFIRHVRK-------------PIVVHCSAGCGRTGTFCAIDMMMQQ------------VDIFQTVKEMRKQRP

GMVQTLDQYIFIFKVIND
|||||..||||. ..| .
GMVQTEEQYIFCYRCILE

Phosphatase ptpC.AA Subfamily.N_Nematode_5.PD 469-713 26 1e-35 114.4 In-house 24-254 (258) Show / Hide
Range on Protein: 469-713
Range on HMM: 24-254/258
Sequence Identity: 26% (64 aa)

NNYGKNRYHDVLPNESTRVrltPIESGDGDYINANYINgeVPNSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEENGKKKADVYYPETSQAQE
.|  |||..||  ...|||     . .| .||||..|.  .... . .|  | |||.|..|||||| .|.   .| |.. ||... ...  || . ...|
knlkknrskdvkilDetrV---kltdeddsYinaskik--lddlekkliltQlPlpdteedFWrmvyqekitsvvllvedeelketavsffpletgdyln

YGSFWIHLHKKVMFKDI-GVSSLHLYKKGEEFPREVVLLHYTQWPDCGAPPSSSHIRTlsVMVNTFKARGSAKNtnGPVIVHCSAGIGRSGTFISININM
 ..|   |    .|     .. .  .|      . . |.|.|..   |...... .  .... ...||   ||.|....|.||.|||. . . . .... 
lgkmfinnrkvevkedekkeytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvik--raiekvlskkqgkn--apvvvvsdlGlgRagtflllsvai

AKIERFgNDPSqmnisIKDSVLELRRQRRGMVQTLDQYIFIFKVIN
 . |      |.. . ..| || |.|..|.|| ......       
eqlnng-kepn-----ideilkkirsqRpgavesliqyasvyaavl

Phosphatase ptpC.AA Subfamily.N_Nematode_6.PD 470-713 31 2e-35 113.6 In-house 24-249 (253) Show / Hide
Range on Protein: 470-713
Range on HMM: 24-249/253
Sequence Identity: 31% (75 aa)

NYGKNRYHDVLPNESTRVRLTpieSGDGDYINANYINgeVPNSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEENGKKKADVYYPET-SQAQE
.  .|||...   . .|..|.     .  || ||...  .   .| .| .|||| .||..||.|.    .  || | .| |.||.|.  |....  .|. 
fkdrnrytniqCcdagrlkla---ddedfyihanlvk--istkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvGdark

YGSFW--IHLHKKVMFKDIGVSSLHLYKKGEEFPrEVVLLHYTQWPDCGAPPSS-SHIRTLSVMvntfkargsaKNTNGPVIVHCSAGIGRSGTFISINI
.. .   |.. .| . | .  | . . |.|.|    |  .|. .||| | | |  | .| |||.|... |..||||||.|| ||.. | | .. .     
itklctvikigrkdidkilvrslkrivkagdeev-ivkhihWanWPdhGvPdsflsalrllsvv----------kkdkkPivvhCsaGvGrtGtlalili

NMAKIERfgndPSqmNISIKDSVLELRRQRRGMVQTLDQYIFIFKVIN
 |    ...||..  ||..|   |||  ||.. .. .           
ilealrl----pd--fqgvkdllvklreerfravqtevqylyalrcvl

Phosphatase ptpC.AA Subfamily.N_Nematode_egg.PD 450-713 26 3.3e-32 103.1 In-house 7-253 (257) Show / Hide
Range on Protein: 450-713
Range on HMM: 7-253/257
Sequence Identity: 26% (71 aa)

NDLDNrKHDEEKFFSALQPNNYGKNRYHDVLPNESTRVRLTpIESG--DGDYINANYINGEvPnSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTK
. |..   ||. .  |.. |.  | | . |  .||.||.|  .. |   .|.| ||...|. |  .  .| .||||  | .||||||..|.   || || 
eiler-svdeislttaasdnylekarskrvhckessrvkle-lrrGqylddfihanrvkGk-p-llnefilaqaplkntvedfwrmvfqekvqyivmlts

LEENgkKKADVYYPETS-QAQEY--GSFWIHLHKKVMFKDIGVSSLHLYKKGEEfpREVVLLHYTQWpdcgappsssHIRTLSVMVNTFKARGSAKNTNG
  |.  .. . |.| .  ..  .  ||. |.  |     |      .|   | .  .|   | .|.           .. || .   ..    ..|   |
akes--erceyywpkaeseslvtvpGslrienlkvdskadplfrvtklklvGgd--deelflehwqg----------dvnylsdvysplrvlrklrnlsk

PVIVHCSAGIGRSGTFISININMAKIERfGndPSqMNISIKDSVLELRRQRRGMVQTLDQYIFIFKVIN
|.|..  |. ...|...|.| . .. | |  |  .   .. .|||..||  |..  .|.|.....    
pvvvqdilGvskaatlvaieiallsllr-G--pi-tkslvlravvflrlrrrlsvesvllylfvyrlvl

Phosphatase ptpC.AA Subfamily.R_Nematode_3.PD 463-716 26 5.1e-31 99.2 In-house 21-266 (267) Show / Hide
Range on Protein: 463-716
Range on HMM: 21-266/267
Sequence Identity: 26% (69 aa)

FsalqpNNYGKNRYHDVLPNESTRVRLTP-IESGDGDYINANYIngEVPNSYRyYIACQAPL--------PSTIKDFWRMVWEERSSVIVCLTKLEE---
..  ..|. .|. .|.||| |         |.|.||..  |.||. .  |  |.|.         |||. || |. .|.. ..| | .  |   ....| 
s-----kkvsedrrvevpllektrvvLkgygkrfkddfihAnvv--ecpnglk-lIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedg

NGKKKADVYYPETS-QAQEYGSFWIHL--HKKVMFKDIGVSSLHLyKKGEEFPREVVLLHYTQWPDCGAPPSSSHIRTLSVMVNTFKArgsakntngPVI
  ||||   . .. . . ..    || . .|.   .| . .  .. .  |  |.|. |....|| ..  .  |  .|...|.         ||.||||.|
eeeekcseYypekvdgelkfegvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfvekskt---------pvv

VHCSAGIGRSGTFISININMAKIERFGNdpsqmNISIKDSVLELRRQRRGMVQTLDQYIFIFKVINDVL
|.||.|. .|.. . .| .  .     .... . . |||.|| | .||  ...|.  .| ..|      
VHCsdGisRsatlaaielgyqliikskg-----kldllslikelrkqRagaiqtelelafvilgilkll

Phosphatase ptpC.AA Subfamily.N_Fungi_PTP1.PD 469-565 37 1e-23 75.0 In-house 44-153 (343) Show / Hide
Range on Protein: 469-565
Range on HMM: 44-153/343
Sequence Identity: 37% (39 aa)

NNYGKNRYHDVLPNESTRVRLT-PIES--------GDGDYINANYINGEVP---NSYRY-YIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEENGKKK
. . ||||...|| | .||.|   ..|           |||||||.. ...       . ||| |||||||..||.... .||. ||.. |.. .| . |
elfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlek

ADVYYPETSQ
..| |     
cyrYWqegsy

Phosphatase ptpC.AA Subfamily.N_Fungi_PTP1.PD 600-712 32 8.9e-19 58.8 In-house 212-338 (343) Show / Hide
Range on Protein: 600-712
Range on HMM: 212-338/343
Sequence Identity: 32% (40 aa)

PREVVLLHYTQWPDCGA--PPsSSHIRTLS---VMVNTFKARGSAKNTNG-PVIVHCSAGIGRSGTFISININMAKIERFGN---D------PSQMNISI
| ||  |.. .|.| .    |  | ...|     ....  |.   .| .. |..||||||.|| ||.....  . ..| . |.      .....  |.  
pyevyqlqvknWkDlslllnP-esilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDli

KDSVLELRRQRRGMVQTLDQYIFIFKVI
|.|||.||  |||.|||.|||.. .   
siivnelrkqrismvqnldqfifiYeal

Phosphatase ptpC.AA Subfamily.N_Nematode_eak.PD 469-614 26 1.1e-16 52.1 In-house 25-167 (281) Show / Hide
Range on Protein: 469-614
Range on HMM: 25-167/281
Sequence Identity: 26% (39 aa)

NNYGKNRYHDVLPNESTRVRLTPIESGDGDYINANYIngEVPNSYRYYIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEENGKKKADVYYPETSQAQE
..  .||  ...|..   ||||.       ||||  .  | ..  | ||   ..  . .  ||.|| |..|  || | .  |.. .| | |.|. ..  .
eavnrnrvvkivpqdrylvrltssqlnrdGyinasla--efsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdktevlk

YGSFWIHLHKKVMFKDIGVSSLHLYKKGEEFPReVVLLHYTQWPDC
|| . ..  . .. ..|    |   .||.|  | |   ..  | . 
yGildverkeyavkrniletrllilrkGnethr-vlhykvfGwtet

Phosphatase ptpC.AA Subfamily.DSP23.PD 617-705 26 7.8e-09 26.9 In-house 46-117 (128) Show / Hide
Range on Protein: 617-705
Range on HMM: 46-117/128
Sequence Identity: 26% (23 aa)

PPSSSHIRTLSVMVNtfkargSAKNTNGPVIVHCSAGIGRSGTFISINInmAKIErfgndpsqmNISIKDSVLELRRQRRGMVQTLDQY
||.   .  |  .|.       |.. ...| |||  |.||.||...  .   | |         ... .|.. |.|..|.| ..| .| 
PPaleqvarlvrive------eaekkeeavgvhcalGlGrtGtllacyl--vkee---------glaaddaiaevrkrrkGsietveqe

Phosphatase ptpC.AA Subfamily.N_Nematode_eak.PD 628-715 21 1.1e-06 19.3 In-house 197-279 (281) Show / Hide
Range on Protein: 628-715
Range on HMM: 197-279/281
Sequence Identity: 21% (19 aa)

VMVNTFKARGSAKNTNGPVIvHCSAGIGRSGTFISININMAKIErfgnDPSQMNISIKDSVLELRRQRRGMVQTLDQYIFIFKVINDV
..  |.|    .  .. |.|  .. |  |.|.|. |.. .  |.    .  .   |..| .|  . .|   | .  |. ||.... | 
llrstlkkyihtppsfapii-qsarGsaraGvfvvidllirlid----nkkknlysvedlilkvkskrihsvlvalqhsfiyeivldy

Phosphatase ptpC.AA Subfamily.PTPDC1.PD 595-664 25 2.4e-06 18.3 In-house 126-187 (229) Show / Hide
Range on Protein: 595-664
Range on HMM: 126-187/229
Sequence Identity: 25% (17 aa)

KGEEFPREVVLLHYTQWPDCGAPPSSSHIRTLSVMvntfkarGSAKnTNGPVIVHCSAGIGRSGTFISIN
. ||. |. .  .   ..| |...  . .    |.        .|  ..| . ||| || || |  |.  
dpeelmrqgiyfynfglkDygvasleriLdivkvv-------dfal-eegkiavHCHAGlGRtGvliacy

Phosphatase ptpC.AA Subfamily.CDC14.PD 639-664 45 7.9e-06 16.9 In-house 194-219 (258) Show / Hide
Range on Protein: 639-664
Range on HMM: 194-219/258
Sequence Identity: 45% (11 aa)

AKNTNGPVIVHCSAGIGRSGTFISIN
. ...| ..||| ||.|| ||.|.  
tekaeGaiavhCkaGLGrtgtligcy

Sequence
Name Sequence Type Origin Length Description Download
ptpC.AA Protein None 990 None Fasta, JSON
ptpC.NA RNA None 2973 None Fasta, JSON
ptpC.AA.PD_444-717 Protein Phosphatase Domain None 274 None Fasta, JSON