• Phosphatome.Net

Gene DDB_G0271350

DDB_G0271350
Species: D.discoideum
Alias: DDB_G0271350
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: DSP_Unclassified
Protein domain

Protein domains of DDB_G0271350.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase DDB_G0271350.AA DSPc 2-140 25 1.5e-32 115.4 SMART 1-172 (172) Show / Hide 
Range on Protein: 2-140
Range on HMM: 1-172/172
Sequence Identity: 25% (44 aa)

GISMILDNFLYLGAAKDTK--DEKEMEKLKITHIFSCAGTV--------------------HSPEKYIIANEKFED-------DETVDISEQIEKAYWFI
|.| |. . |||| ...    .  ...|..|||.....  .                    | ......     .|        ....|| .....| ||
GPSEITPH-LYLGSYPHHMEPNPCFLKKHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFI

ERVRMKKGARVFIHCMAGKSRSASIVLSYLLKRDIHSLSDCLFYL-----HSKR-LEIRPNDGFMNQLCDLELK
...  .|| .|..||.|| ||||...  ||.|..  |..|.. ..     ...|   |.||..|. |||..| |
HDC-RQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK
Phosphatase DDB_G0271350.AA Subfamily.DSP19.PD 7-138 36 4.8e-33 104.5 In-house 5-137 (139) Show / Hide 
Range on Protein: 7-138
Range on HMM: 5-137/139
Sequence Identity: 36% (49 aa)

LDNFLYLGAAKDTKDEKEMEKLKITHIFSCA-GTVHS-PEKYIIANEKFEDDETVDISEQIEKAYWFIERVRMKKgARVFIHCMAGKSRSASIVLSYLLK
. ..||||.   ..|.....|||||||.. | |. .  |... . . .  |.. ... .....|  ||| .| |.  ||..|| || |||||.|..||.|
vkprlylgsqdvaadkeilkklkitHilnvavgvpnvfpkdftyksieilDlpetkllsylkealdFieearskd-grvlvHCnAGvSRsasvviaylmk

RDIHSLSDCLFYLHSKRLEIRPNDGFMNQLCDLE
.   ||...| .....|  |.|| ||..||...|
deelslekalekvrearpcikPneGFikqLkeye
Phosphatase DDB_G0271350.AA Subfamily.DSP1.PD 5-137 38 3e-32 102.1 In-house 4-136 (139) Show / Hide 
Range on Protein: 5-137
Range on HMM: 4-136/139
Sequence Identity: 38% (50 aa)

MILdNFLYLGAAKDTKDEKEMEKLKITHIFSCAGTV--HSPEKYIIANEKFEDDETVDISEQIEKAYWFIERVRMKKGaRVFIHCMAGKSRSASIVLSYL
|| .|||||.|... . . ...||||..  .....  . .| .   . . ||....|||...|.|  ||..|. |.| ||..|| || ||||.||| ||.
eil-dfLyLGsaehasnlqlLkelkitallnvsaelpnvfeelfkyksipvednkkadisslfeeaidfidsvkkkgG-rvlvhCqaGisrsativlayL

LKRDIHSLSDCLFYLHSKRLEIRPNDGFMNQLCDL
|..  .|..   .....|  | || ||..||    
mkekkvrleeafefvkqrrsiisPnfgfvgqLlef
Phosphatase DDB_G0271350.AA DSPc 11-140 26 1.6e-30 108.09 Pfam 1-151 (151) Show / Hide 
Range on Protein: 11-140
Range on HMM: 1-151/151
Sequence Identity: 26% (40 aa)

LYLGAAKDTK-DEKEMEKLKITHIFSCAGTVHS------PEKYIIANEKFED---------DETVDISEQIEKAYWFIERVRMKKGARVFIHCMAGKSRS
||||.... . |.  ..|..|||...|.  .        ......     .|          ....||  ...|. ||... ..|| .| .||.|| |||
LYLGSYPHHMADPAFLQKHGITHVINCTMECPNNWFYHNSHFHYMWIPHVHDHIHYYHIHWNHCTNISQYFPMATDFIDDC-RQKGGKVLVHCQAGISRS

ASIVLSYLLKRDIHSLSDCLFYL-----HSKR-LEIRPNDGFMNQLCDLELK
|.... ||.|..  |..... ..      ..|   |.||..|. |||..| .
ACLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ
Phosphatase DDB_G0271350.AA Family.DSP.PD 4-172 27 3.5e-29 92.8 In-house 108-275 (387) Show / Hide 
Range on Protein: 4-172
Range on HMM: 108-275/387
Sequence Identity: 27% (47 aa)

SMILDnFLYLGAAKDTKDEKEMEKLKITHIFSCAGTVHSpEKY----IIANEKFEDDETVDISEQIEKAYWFIERVRmKKGARVFIHCMAGKSRSASIVL
| ||. .|||| ... |.......|..|.| ...   .. ...     . .  ..| .. .... .|||. ||| .. ... .|..||.|||.||.... 
seilp-hlylgsllaaknlewlkelgvtkivnltddkpq-ftkelgikylripidDhnapplenlfekaidfieegn-dskgvVlVHCkaGkgRsgtlii

SYLLKRDIHSLSDCLFYLHSKRL-EIRPNDGFMNQLCDLELKLTNKQTLSKEIKEWRSlqsKALKTKIDVQTCH
 ||.|.   .|...| .. |||   |.||.||. || ||| .. . ..   |.. ..|   .  .   .|. . 
aYlmksegltleealdwvrskRpgvitpnqgflkqlkdlekeklkvssevmelrfvis---sivqnlgsvevsv
Phosphatase DDB_G0271350.AA Subfamily.DSP12.PD 9-134 33 1.8e-27 86.7 In-house 7-135 (143) Show / Hide 
Range on Protein: 9-134
Range on HMM: 7-135/143
Sequence Identity: 33% (44 aa)

NFLYLGAAKDTKDEKEMEKLKITHIFSCAGTVHsPEKYII-----ANEKFEDDETVDISEQIEKAYWFIERVRmKKGARVFIHCMAGKSRSASIVLSYLL
. |||| ... ........|||||. | . .   ||. ..      . .  |... |. . ...|  |||  . .|.  |..||.|| |||..||. ||.
pglylggleavqerellkelkithvlsvikeel-pelqkekgvkskliqilDepeedlLshldeavrFieegl-ekegavlvHClagvSRSvtiviAYlm

KRDIHSLSDCLFYLHSKRLEIRPNDGFMNQL
|..  ||.. |  ...|. ||.||.||..||
kkeklslekAlklvkekkkeiepNegFleQL
Phosphatase DDB_G0271350.AA Subfamily.DSP10.PD 9-138 33 1.5e-26 83.4 In-house 7-139 (141) Show / Hide 
Range on Protein: 9-138
Range on HMM: 7-139/141
Sequence Identity: 33% (45 aa)

NFLYLGAAKDTKDEKEMEKLKITHIFSCAGTvhSPEKYI------IANEKFEDDETVDISEQIEKAYWFIERVRmKKGARVFIHCMAGKSRSASIVLSYL
||.||. ||..|.. ...| |....  . .  .| ..         . . .| .. ..... |.|. ||| .| |.|.||..||.|| |||| .|..|..
pflllGnekdaadkdaldrlgikyvlnvtts--vPnffeekglvrykripvsdsgkqnlkqkfeealefieear-krgsrvlvhchaGisrsatvviayv

LKRDIHSLSDCLFYLHSKRLEIRPNDGFMNQLCDLE
|    |||.   .. .||  | || .|| || ..| 
mkhlslslseaykfvkekrPiisPnlnfmGqllefe
Phosphatase DDB_G0271350.AA Subfamily.DSP14.PD 8-139 34 1.8e-26 83.4 In-house 6-137 (138) Show / Hide 
Range on Protein: 8-139
Range on HMM: 6-137/138
Sequence Identity: 34% (45 aa)

DNFLYLGaAKDTKDEKEMEKLKITHIFSCAGTVHSPEKY--IIANEKFEDDETVDISEQIEKAYWFIERVRMKKGaRVFIHCMAGKSRSASIVLSYLLKR
. |||. ..  .......| |||.|   .  . ...       . | ||... ...|  ....  || |..|.| ....||.|| |||||.|| ||.| .
tesLyls-gaaalkkeklkkkkitlivnvttelpetkledvktvkikveDkpeaklaehfdevadkieevkkkgG-ktlvhCvaGvsRsAslvlaylmky

DIHSLSDCLFYLHSKRLEIRPNDGFMNQLCDLEL
  || .   ...|.|  |||| || .|| |.|  
eklsLreayklvksaRpiirPnvGFwkqlidyEk
Phosphatase DDB_G0271350.AA Subfamily.DSP3.PD 11-138 33 9.9e-26 80.9 In-house 9-146 (148) Show / Hide 
Range on Protein: 11-138
Range on HMM: 9-146/148
Sequence Identity: 33% (46 aa)

LYLGAAKDTKDEKEMEKLKITHIFSCAGT-----VH-SPEKYIIANE-----KFEDDETVDISEQIEKAYWFIERVRMKKGARVFIHCMAGKSRSASIVL
.|.| ..  ||.....|| |||.. .| .     |.  .| |  ..      . .|  ..|.|.  |.|  ||..   .|...|..||..||||| .||.
vyvgdeavakdkekLkklGithvLnaaegkrllkvdtdaefYkdleikylGvevsDvpefdlskyfeeaadfidealsqkngkvlvhcvvGisRsatlvl

SYLLKRDIHSLSDCLFYLHSKRlEIRPNDGFMNQLCDLE
||. |   .| . .   ..|| || ||.||..||..|. 
ayLmirrkltlkeaiktvrkkr-eilPneGflkqLleld
Phosphatase DDB_G0271350.AA Subfamily.DSP6.PD 6-138 33 9.9e-25 77.4 In-house 5-139 (141) Show / Hide 
Range on Protein: 6-138
Range on HMM: 5-139/141
Sequence Identity: 33% (46 aa)

ILDnFLYLGAAKDTKDEKEMEKLKITHIFSCAGT----VHSPEKYIIANEKFEDDETVDISEQIEKAYWFIERVRMKKgARVFIHCMAGKSRSASIVLSY
||. .||||.|||... . ..|||| ...  .       .. ..    .   ||  . .... . .|  ||.  | || . |..||.|| ||| ...|.|
ilp-llylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkykqipiedhlsqnlakffPeaiefidearskk-skvlvhclaGvsrsvtvtlay

LLKRDIHSLSDCLFYLHSKRLEIRPNDGFMNQLCDLE
|.|.   || |   ....|. .| ||  ||.|| | |
lmkklalslndaydlvkkkksnisPnfnfmgqlldfe
Phosphatase DDB_G0271350.AA Subfamily.Slingshot.PD 9-135 33 1.6e-24 76.8 In-house 7-134 (139) Show / Hide 
Range on Protein: 9-135
Range on HMM: 7-134/139
Sequence Identity: 33% (43 aa)

NFLYLGAAKDTKDEKEMEKLKITHIFSCAGTVHS--PEKYIIANEKFEDDETVDISEQIEKAYWFIERVRmKKGARVFIHCMAGKSRSASIVLSYLLKRD
..||||.  .. . .|... ....|.  .  ...  |||.   | .  |.|. |. .. ...| |||... .||..|..||  | |||||.|..| .|. 
dhlylGsewnasnleelkengveyilnvtkeidnffpekfkylnirvydeeetdllkhwnetykfiekak-ekgskvlvhckmGvsrsastviayamkey

IHSLSDCLFYLHSKRLEIRPNDGFMNQLC
  || ..| |....|  |.||.||..|| 
elsleealeyvkerrsiikpnkgflkqlk
Phosphatase DDB_G0271350.AA Subfamily.DSP8.PD 9-140 31 5.8e-24 75.2 In-house 7-141 (143) Show / Hide 
Range on Protein: 9-140
Range on HMM: 7-141/143
Sequence Identity: 31% (43 aa)

NFLYLGAAKDTKDEKEMEKLKITHIF----SCAGTVHSPEKYIIANEKFEDDETVDISEQIEKAYWFIERVRMKKGaRVFIHCMAGKSRSASIVLSYLLK
..||||. ||. ||. ..|| |....    ||  .|.  ..  .     .|. . .... ..||. ||...| ..| .|..||.||.||||.....|..|
pnlylGsqkdsldeellkklgisyvlnisescpkdvellkesrflriPvkDkyeekllpwfdkalefidkarsang-kvlvhclaGisrsatvaiayimk

RDIHSLSDCLFYLHSKRLEIRPNDGFMNQLCDLELK
.   || ..  ....||  | ||  |..|| . | .
tlemsldeayrfvkekrptispnlnflgqLleyeke
Phosphatase DDB_G0271350.AA Subfamily.LRR-DSP.PD 6-138 35 2.2e-22 69.9 In-house 5-135 (137) Show / Hide 
Range on Protein: 6-138
Range on HMM: 5-135/137
Sequence Identity: 35% (48 aa)

ILDNfLYLGAAKDTKDEKEMEKLKITHIFSCAGTV-HSPE--KYIIAneKFEDDETVDISEQIEKAYWFIERVRMKKGarVFIHCMAGKSRSASIVLSYL
|.|. ||||. . ....  ......|||.. |      |.  ||.|   . || . .||.. ...   ||.  | | |  |.||| ||||||..|..||.
iidk-lylgcresamnksilkdnnvthilavadfkplypdlfkylii--diedvdeadiyqhfkemnafidegrekgg--vlihcragvsrsatlviayl

LKRDIHSLSDCLFYLHSKRLEIRPNDGFMNQLCDLE
|..   . . |    .|| .|.|| ||..||   | 
mkknslkfkealdlvikkrpriypnrgfldqlkkfe
Phosphatase DDB_G0271350.AA Subfamily.DSP15.PD 10-138 32 6.8e-22 68.4 In-house 8-136 (138) Show / Hide 
Range on Protein: 10-138
Range on HMM: 8-136/138
Sequence Identity: 32% (42 aa)

FLYLGAAKDTKDEKEMEKLKITHIFSCAGTVHS--PEkYIIANEKFEDDETVDISEQIEKAYWFIERVRMKkGARVFIHCMAGKSRSASIVLSYLLKRDI
||.|  .|.||.. .|. |||||.|   . .   ..       | .|   .|.|.  ...  || ..|.. |  |..||.|| ||| ..|.|..     |
GlyvGnfrdakdkeqleenkithilsihdsakplled-ikylcikaadsPdqdlskffkesidfihkcrle-ggnvlvhclaGisrsvtlvvayimtvte

HSLSDCLFYLHSKRLEIRPNDGFMNQLCDLE
  |.|  ... |    || || .|| . |  
lswedalkavkaarsvanPnvGfrrqlqefe
Phosphatase DDB_G0271350.AA Subfamily.STYXL1.PD 6-138 24 3.4e-16 50.2 In-house 5-141 (143) Show / Hide 
Range on Protein: 6-138
Range on HMM: 5-141/143
Sequence Identity: 24% (34 aa)

ILDNFLYLGAAKDTKDEKEMEKLKITHIFSC---AGTVHSPEKY--IIANEKFEDDETVDISEQIEKAYWFIERVRMkKGARVFIHCMAGKSRSASIVLS
.| ..||||  |......  . ||.         |. . .  .    . . . ||..  |. |.....  |||. .  .|  |..    |||||.....|
vlPgklylGnykqaqnpaikkdlkvkahvnvssdaekliagladvakllhiavedeneadllerlkevvqfiekhkk-egevvlvfsnkGisrsaaviia

YLLKRDIHSLSDCLFYLHSKRLEIRPNDGFMNQLCDLE
|.     .| ... ||.  . ...|| .|..|| . | 
ylmyskkitlkkaykylkkckenvkPnrafveqlseWe
Phosphatase DDB_G0271350.AA Subfamily.PTPMT1.PD 62-129 39 7.2e-15 45.6 In-house 69-135 (146) Show / Hide 
Range on Protein: 62-129
Range on HMM: 69-135/146
Sequence Identity: 39% (26 aa)

SEQIEKAYWFIERVRmKKGARVFIHCMAGKSRSASIVLSYLLKRDIHSLSDCLFYLHSKRLEIRPNDG
|..|..  |||.|. .|| .|..|| ||..|||..| .||.|.   |  .   .|..|| .|| ..  
lekleegvefiekva-skgssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpqirlksk
Phosphatase DDB_G0271350.AA Subfamily.STYX.PD 55-137 30 1e-12 38.6 In-house 62-143 (146) Show / Hide 
Range on Protein: 55-137
Range on HMM: 62-143/146
Sequence Identity: 30% (25 aa)

DDETVDISEQIEKAYWFIERVrMKKGARVFIHCMAGKSRSASIVLSYLLKRDIHSLSDCLFYLHSKRLEIRPNDGFMNQLCDL
|. . .|   . ..  ||.   ..|| .|..|  || ||||..|..|...       ..  |.  .|. | ||.||..|| . 
dntveniirylptvkefidds-lqkggkvlvhgnagisrsaalviayimetyglkyreafayvqerrfcinpnegfvsqlkey
Phosphatase DDB_G0271350.AA Subfamily.Laforin.PD 76-121 37 4.1e-07 20.3 In-house 100-145 (165) Show / Hide 
Range on Protein: 76-121
Range on HMM: 100-145/165
Sequence Identity: 37% (17 aa)

RMKKGARVFIHCMAGKSRSASIVLSYLLKRDIHSLSDCLFYLHSKR
..|| .|..|| ||  ||..||  .|      ||.   ..| .|| 
llekghivyvhcnagvgrstaivcgflqyvlgwslakvqyfllakr
Phosphatase DDB_G0271350.AA Subfamily.PTEN.PD 83-121 37 1.8e-06 18.0 In-house 97-136 (305) Show / Hide 
Range on Protein: 83-121
Range on HMM: 97-136/305
Sequence Identity: 37% (15 aa)

VFIHCMAGKSRSASIVLSYLLKRDIHSLS-DCLFYLHSKR
| .|| ||| |.  .. .||||. | .   . | . ..||
vavHCkaGkGRtGvmicayLlksgikksadealaiydekR
Phosphatase DDB_G0271350.AA Subfamily.DSP23.PD 62-114 26 2.7e-06 18.0 In-house 49-100 (128) Show / Hide 
Range on Protein: 62-114
Range on HMM: 49-100/128
Sequence Identity: 26% (14 aa)

SEQIEKAYWFIERVRmKKGARVFIHCMAGKSRSASIVLSYLLKRDIHSLSDCL
||... .  .|    ||.  | .||. |  |. ...  ||.| .  . .| . 
leqvarlvriveeae-kkeeavgvhcalGlGrtGtllacylvkeeglaaddai
Phosphatase DDB_G0271350.AA Subfamily.R_Nematode_3.PD 42-164 25 2.8e-06 17.4 In-house 161-251 (267) Show / Hide 
Range on Protein: 42-164
Range on HMM: 161-251/267
Sequence Identity: 25% (23 aa)

SPEKYIIANEKFEDDETVDISEQIEKAYWFIERVRMKKgARVFIHCMAGKSRSASIVLsyllkrdihslsdclfylhskrleirpndgfMNQLCDLELKL
..  .    ... .   . |. ..|   |. |.  | . | .||..| ||||.....  ..| .| ..|..| . ||| |.   .|..|           
kkkeftvthllykgWkelnapeepkealelikfveksk-tpvvVHCsdGisRsatlaa-------------------------------ielgyqliiks

TNKQTLSKEIKEWRSLQSKALKT
                       
kgkldllslikelrkqRagaiqt
Phosphatase DDB_G0271350.AA Subfamily.TPIP.PD 82-125 33 9.5e-06 15.9 In-house 39-83 (245) Show / Hide 
Range on Protein: 82-125
Range on HMM: 39-83/245
Sequence Identity: 33% (14 aa)

RVFIHCMAGKSRSASIVLSYLLKRDIHSL-SDCLFYLHSKRLEIR
|.|||  || |   || ..|.. .| .   ..| |. ..| .   
vvaihckGGkgrtGtivcalliaseifltaeesldyfgerrtdkt
Sequence
Name Sequence Type Origin Length Description Download
DDB_G0271350.AA Protein None 275 None Fasta, JSON
DDB_G0271350.NA RNA None 828 None Fasta, JSON
DDB_G0271350.AA.PD_2-140 Protein Phosphatase Domain None 139 None Fasta, JSON