Gene DDB_G0271860
DDB_G0271860
Species: D.discoideum
Alias: DDB_G0271860
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of DDB_G0271860.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | DDB_G0271860.AA | DSPc | 337-477 | 30 | 5.9e-44 | 153.26 | SMART | 1-172 (172) | Show / Hide |
Range on Protein: 337-477 Range on HMM: 1-172/172 Sequence Identity: 30% (52 aa) ICSKVTDYLYMGSETVAS--NLEILKSNGITHIINASHQCDN---------------FFQDNPMFEYRKLH-LRD-------SPLEDISLVFEQVIEFIE .|..| .|| ||..... |.. || ..|||.||.. |.. . |. |.| . . | .. ..|| |..|..||. GPSEITPHLYLGSYPHHMEPNPCFLKKHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFIH RAIACNGKIFIHCQMGVSRSSCLCMLWIMKTTRCSLEEASDLV-----KQVR-PISRPNAGFQLSLLNWAIK .... .||...|||.|.||| .||. ..||. .|...| ..| ||.| || .||..|. .|. | | DCRQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK |
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| Phosphatase | DDB_G0271860.AA | Subfamily.DSP1.PD | 339-475 | 38 | 2.7e-44 | 140.9 | In-house | 3-137 (139) | Show / Hide |
Range on Protein: 339-475 Range on HMM: 3-137/139 Sequence Identity: 38% (53 aa) SKVTDYLYMGSETVASNLEILKSNGITHIINASHQCDNFFQDnpMFEYRKLHLRDSPLEDISLVFEQVIEFIERAIACNGKIFIHCQMGVSRSSCLCMLW ... |.||.||.. ||||..||. .||...| | ...| |.. .|.|..... |.. .||| ||..|.||... ...|....|||.|.|||. ..... veildfLyLGsaehasnlqlLkelkitallnvsaelpnvfee--lfkyksipvednkkadisslfeeaidfidsvkkkgGrvlvhCqaGisrsativlay IMKTTRCSLEEASDLVKQVRPISRPNAGFQLSLLNWA .||.....|||| . ||| | |. || || ||.. LmkekkvrleeafefvkqrrsiisPnfgfvgqLlefe |
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| Phosphatase | DDB_G0271860.AA | DSPc | 345-477 | 33 | 2.2e-41 | 145.84 | Pfam | 1-151 (151) | Show / Hide |
Range on Protein: 345-477 Range on HMM: 1-151/151 Sequence Identity: 33% (50 aa) LYMGSETVAS-NLEILKSNGITHIINASHQCDN-FFQDNPMFEYRKLH-LRD---------SPLEDISLVFEQVIEFIERAIACNGKIFIHCQMGVSRSS || ||..... ....|. .||||.||.. |.| .| |. |.| .. . | .. ..|| |.....||..... .||. .|||.|.||| LYLGSYPHHMADPAFLQKHGITHVINCTMECPNNWFYHNSHFHYMWIPHVHDHIHYYHIHWNHCTNISQYFPMATDFIDDCRQKGGKVLVHCQAGISRSA CLCMLWIMKTTRCSLEEASDLV-----KQVR-PISRPNAGFQLSLLNWAIK |||. ..||. ..|..|| |.| ||.| |. .||..|. .|. . . CLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ |
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| Phosphatase | DDB_G0271860.AA | Subfamily.DSP19.PD | 339-473 | 35 | 1.3e-37 | 119.1 | In-house | 3-135 (139) | Show / Hide |
Range on Protein: 339-473 Range on HMM: 3-135/139 Sequence Identity: 35% (48 aa) SKVTDYLYMGSETVASNLEILKSNGITHIINASHQCDNFFQDNpmFEYRKLHLRDSPLEDISLVFEQVIEFIERAIACNGKIFIHCQMGVSRSSCLCMLW ..|...||.|| ||...||||...||||.| . . .|.| .. |.| .... | | ... .......||| | .| ...||. |||||. . . . aevkprlylgsqdvaadkeilkklkitHilnvavgvpnvfpkd--ftyksieilDlpetkllsylkealdFieearskdgrvlvHCnAGvSRsasvviay IMKTTRCSLEEASDLVKQVRPISRPNAGFQLSLLN .||... |||.| . |.. || .||.||. | . lmkdeelslekalekvrearpcikPneGFikqLke |
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| Phosphatase | DDB_G0271860.AA | Subfamily.Slingshot.PD | 339-471 | 42 | 5.9e-36 | 113.7 | In-house | 3-133 (139) | Show / Hide |
Range on Protein: 339-471 Range on HMM: 3-133/139 Sequence Identity: 42% (56 aa) SKVTDYLYMGSETVASNLEILKSNGITHIINASHQCDNFFQDNpmFEYRKLHLRDSPLEDISLVFEQVIEFIERAIACNGKIFIHCQMGVSRSSCLCMLW ||. |.||.||| ||||| || ||...|.| ....||||... |.| .... |.. .|. ... .|||.| . . |...||.||||||.. . . skifdhlylGsewnasnleelkengveyilnvtkeidnffpek--fkylnirvydeeetdllkhwnetykfiekakekgskvlvhckmGvsrsastviay IMKTTRCSLEEASDLVKQVRPISRPNAGFQLSL ||. ..||||| . ||. | | .||.|| | amkeyelsleealeyvkerrsiikpnkgflkql |
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| Phosphatase | DDB_G0271860.AA | Subfamily.DSP10.PD | 339-474 | 32 | 1.6e-35 | 112.3 | In-house | 3-138 (141) | Show / Hide |
Range on Protein: 339-474 Range on HMM: 3-138/141 Sequence Identity: 32% (44 aa) SKVTDYLYMGSETVASNLEILKSNGITHIINASHQCDNFFQDNPMFEYRKLHLRDSPLEDISLVFEQVIEFIERAIACNGKIFIHCQMGVSRSSCLCMLW |.. .|..|.|. |.. ..|. ||....| .. |||... ...|... ..||. .... ||. .|||| | .......||. |.|||. . . . ssilpflllGnekdaadkdaldrlgikyvlnvttsvPnffeekglvrykripvsdsgkqnlkqkfeealefieearkrgsrvlvhchaGisrsatvviay IMKTTRCSLEEASDLVKQVRPISRPNAGFQLSLLNW .|| .. ||.|| .||. ||| || .| ||.. vmkhlslslseaykfvkekrPiisPnlnfmGqllef |
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| Phosphatase | DDB_G0271860.AA | Subfamily.DSP14.PD | 338-473 | 34 | 4.1e-33 | 104.7 | In-house | 2-134 (138) | Show / Hide |
Range on Protein: 338-473 Range on HMM: 2-134/138 Sequence Identity: 34% (47 aa) CSKVTDYLYMGsETVASNLEILKSNGITHIINASHQCDNFFqdNPMFEYRKLHLRDSPLEDISLVFEQVIEFIERAIACNGKIFIHCQMGVSRSSCLCML .|..|..||.. ..|.. | ||...||.|.|.. . . . ... |....|.| .... |..| . || . . .||...|| .||||| |.. lseitesLyls-gaaalkkeklkkkkitlivnvttelpetk--ledvktvkikveDkpeaklaehfdevadkieevkkkgGktlvhCvaGvsRsAslvla WIMKTTRCSLEEASDLVKQVRPISRPNAGFQLSLLN ..|| . ||.|| |||. ||| ||| || | . ylmkyeklsLreayklvksaRpiirPnvGFwkqlid |
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| Phosphatase | DDB_G0271860.AA | Subfamily.DSP12.PD | 339-472 | 30 | 4.7e-32 | 101.4 | In-house | 3-136 (143) | Show / Hide |
Range on Protein: 339-472 Range on HMM: 3-136/143 Sequence Identity: 30% (40 aa) SKVTDYLYMGSETVASNLEILKSNGITHIINASHQCDNFFQDNPMFEYRKLHLRDSPLEDISLVFEQVIEFIERAIACNGKIFIHCQMGVSRSSCLCMLW |.... ||.|. . . . | ||. |||.. .. . .|... ... ... |.| ||. ......||| ... .|....||..|||||. ... . seilpglylggleavqerellkelkithvlsvikeelpelqkekgvkskliqilDepeedlLshldeavrFieeglekegavlvHClagvSRSvtiviAY IMKTTRCSLEEASDLVKQVRPISRPNAGFQLSLL .||....|||.| .|||.... .||.||. | lmkkeklslekAlklvkekkkeiepNegFleQLk |
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| Phosphatase | DDB_G0271860.AA | Subfamily.DSP6.PD | 340-473 | 34 | 1.7e-31 | 99.1 | In-house | 4-137 (141) | Show / Hide |
Range on Protein: 340-473 Range on HMM: 4-137/141 Sequence Identity: 34% (45 aa) KVTDYLYMGSETVASNLEILKSNGITHIINASHQCDNFFQDNPMFEYRKLHLRDSPLEDISLVFEQVIEFIERAIACNGKIFIHCQMGVSRSSCLCMLWI .....||.||.. |||||.|| .| ...| ... .|.|.... ..| .. ..| .... | . ||||. | . |...|| |||||... ..|| eilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkykqipiedhlsqnlakffPeaiefidearskkskvlvhclaGvsrsvtvtlayl MKTTRCSLEEASDLVKQVRPISRPNAGFQLSLLN .. .||..| ||||. .. || | ||. mkklalslndaydlvkkkksnisPnfnfmgqlld |
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| Phosphatase | DDB_G0271860.AA | Subfamily.DSP8.PD | 339-475 | 33 | 5.6e-30 | 94.5 | In-house | 3-139 (143) | Show / Hide |
Range on Protein: 339-475 Range on HMM: 3-139/143 Sequence Identity: 33% (45 aa) SKVTDYLYMGSETVASNLEILKSNGITHIINASHQCDNFFQDNPMFEYRKLHLRDSPLEDISLVFEQVIEFIERAIACNGKIFIHCQMGVSRSSCLCMLW .....||.||.... . |.|| .||....|.|..|. . . .. .. ..|. |... .|.. .|||..| . |||...|| | |||. . . .| trilpnlylGsqkdsldeellkklgisyvlnisescpkdvellkesrflriPvkDkyeekllpwfdkalefidkarsangkvlvhclaGisrsatvaiay IMKTTRCSLEEASDLVKQVRPISRPNAGFQLSLLNWA ||| . ||.|| ||. || || | ||.. imktlemsldeayrfvkekrptispnlnflgqLleye |
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| Phosphatase | DDB_G0271860.AA | Subfamily.DSP3.PD | 339-472 | 35 | 1.2e-28 | 90.2 | In-house | 3-143 (148) | Show / Hide |
Range on Protein: 339-472 Range on HMM: 3-143/148 Sequence Identity: 35% (50 aa) SKVTDYLYMGSETVASNLEILKSNGITHIINASHQCD--------NFFQDNpMFEYRKLHLRDSPLEDISLVFEQVIEFIERAIAC-NGKIFIHCQMGVS |.. .|.| |.||.. | || ||||..||.... .|..| .| .. .|.| |.| ||. .||..|.. |||...||..|.||| devypkvyvgdeavakdkekLkklGithvLnaaegkrllkvdtdaefYkdl-eikylGvevsDvpefdlskyfeeaadfidealsqkngkvlvhcvvGis RSSCLCMLWIMKTTRCSLEEASDLVKQVRPIsRPNAGFQLSLL . | . ..| . . .|.|| |.. | | || || || RsatlvlayLmirrkltlkeaiktvrkkrei-lPneGflkqLl |
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| Phosphatase | DDB_G0271860.AA | Subfamily.LRR-DSP.PD | 338-474 | 34 | 1.7e-28 | 89.5 | In-house | 2-134 (137) | Show / Hide |
Range on Protein: 338-474 Range on HMM: 2-134/137 Sequence Identity: 34% (47 aa) CSKVTDYLYMGSETVASNLEILKSNGITHIiNASHQCDNFFQDnpMFEYRKLHLRDSPLEDISLVFEQVIEFIERAIAcNGKIFIHCQMGVSRSSCLCML ... | ||.|. | | |||.|..||| | ... .. | .| | ....| . ||. |... ||. .| ..|||.|||||..| . .. pdliidklylgcresamnksilkdnnvthi-lavadfkplypd--lfkyliidiedvdeadiyqhfkemnafidegre-kggvlihcragvsrsatlvia WIMKTTRCSLEEASDLVKQVRPISRPNAGFQLSLLNW || . ..|| |||.. || .|| ||. |. . ylmkknslkfkealdlvikkrpriypnrgfldqlkkf |
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| Phosphatase | DDB_G0271860.AA | Subfamily.DSP15.PD | 339-474 | 33 | 1.7e-28 | 89.6 | In-house | 3-135 (138) | Show / Hide |
Range on Protein: 339-474 Range on HMM: 3-135/138 Sequence Identity: 33% (46 aa) SKVTDYLYMGSETVASNLEILKSNGITHIINASHQCDNFFQDnpmFEYRKLHLRDSPLEDISLVFEQVIEFIERAIACNGKIFIHCQMGVSRSSCLCMLW .|| ||.|. . |.. | |. | ||||. . . ...| ..|. .. ||| |.| |.. |.|| .. .|....|| |.||| |.. . nkvlpGlyvGnfrdakdkeqleenkithilsihdsakplled---ikylcikaadsPdqdlskffkesidfihkcrleggnvlvhclaGisrsvtlvvay IMKTTRCSLEEASDLVKQVRPISRPNAGFQLSLLNW || | | |.| ||. |... ||.||. | .. imtvtelswedalkavkaarsvanPnvGfrrqlqef |
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| Phosphatase | DDB_G0271860.AA | Family.DSP.PD | 338-475 | 33 | 2.2e-23 | 73.5 | In-house | 107-244 (387) | Show / Hide |
Range on Protein: 338-475 Range on HMM: 107-244/387 Sequence Identity: 33% (46 aa) CSKVTDYLYMGSETVASNLEILKSNGITHIINASHQCDNfFQDNPMFEYRKLHLRDSPLEDISLVFEQVIEFIERAIACNGKIFIHCQMGVSRSSCLCML .|.... ||.|| |.||| || .|.|.|.|....... |. . ..| .... |.. ......||..|.||| . ..|....||..|..|||.. .. pseilphlylgsllaaknlewlkelgvtkivnltddkpq-ftkelgikylripidDhnapplenlfekaidfieegndskgvVlVHCkaGkgRsgtliia WIMKTTRCSLEEASDLVKQVRP-ISRPNAGFQLSLLNWA || ...|||| |.|...|| . .|| || | . YlmksegltleealdwvrskRpgvitpnqgflkqlkdle |
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| Phosphatase | DDB_G0271860.AA | Subfamily.STYX.PD | 345-473 | 33 | 6.7e-20 | 61.8 | In-house | 9-142 (146) | Show / Hide |
Range on Protein: 345-473 Range on HMM: 9-142/146 Sequence Identity: 33% (45 aa) LYMG--SETVASNLEILKSNGITHIINASHQCD-NFFQDN--PMFEYRKLHLRDSPLEDISLVFEQVIEFIERAIACNGKIFIHCQMGVSRSSCLCMLWI |..| | .. |.||.||..|||||. . . |. . | | | | . |...|.| . .| |||. .. ||...| . |.|||..| . .| lflgpysaamksklevlkehgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaalviayi MKTTRCSLEEASDLVKQVRPISRPNAGFQLSLLN |.| || |.. | ||.|| | . metyglkyreafayvqerrfcinpnegfvsqlke |
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| Phosphatase | DDB_G0271860.AA | Subfamily.STYXL1.PD | 343-474 | 21 | 2.2e-14 | 44.2 | In-house | 8-140 (143) | Show / Hide |
Range on Protein: 343-474 Range on HMM: 8-140/143 Sequence Identity: 21% (28 aa) DYLYMGSETVASNLEILKSNGITHIINASHQCDNFFQDNPM-FEYRKLHLRDSPLEDISLVFEQVIEFIERAIACNGKIFIHCQMGVSRSSCLCMLWIMK . ||.| . | | .| | . .| |........ . . .....|.. |. ...|..|||. . ... . |.|||.. . ..| gklylGnykqaqnpaikkdlkvkahvnvssdaekliagladvakllhiavedeneadllerlkevvqfiekhkkegevvlvfsnkGisrsaaviiaylmy TTRCSLEEASDLVKQVRPISRPNAGFQLSLLNW . .|..| . .|. .. .|| .| | .| skkitlkkaykylkkckenvkPnrafveqlseW |
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| Phosphatase | DDB_G0271860.AA | Subfamily.PTPMT1.PD | 403-462 | 35 | 6.1e-13 | 39.1 | In-house | 72-131 (146) | Show / Hide |
Range on Protein: 403-462 Range on HMM: 72-131/146 Sequence Identity: 35% (21 aa) FEQVIEFIERAIACNGKIFIHCQMGVSRSSCLCMLWIMKTTRCSLEEASDLVKQVRPISR |. .||||. . . ....||. | .||. | ..||....| ||| ...|. ||. | leegvefiekvaskgssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpqir |
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| Phosphatase | DDB_G0271860.AA | Subfamily.CDC14.PD | 356-460 | 22 | 1.5e-09 | 28.2 | In-house | 140-241 (258) | Show / Hide |
Range on Protein: 356-460 Range on HMM: 140-241/258 Sequence Identity: 22% (23 aa) LEILKSNGITHIINASHQcdnfFQDNPMFEYRKLHLRDSPLEDISLVFEQVI-EFIERAIACNGKIFIHCQMGVSRSSCLCMLWIMKTTRCSLEEASDLV || ..|..|.|. .. |. |. .. | .| . .... .|.| . ..|.| .||. |. | ..| ...|. |. .|. .. leyfrknnvttivrLnkk----lYdakkftdaGfahlDlffiDGtvPsdailkkfleitekaeGaiavhCkaGLGrtgtligcylikhyrftaaetiawl KQVRPI .|| riarPG |
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| Phosphatase | DDB_G0271860.AA | Subfamily.DSP23.PD | 355-460 | 17 | 4e-08 | 23.7 | In-house | 5-109 (128) | Show / Hide |
Range on Protein: 355-460 Range on HMM: 5-109/128 Sequence Identity: 17% (18 aa) NLEILKSNGITHIINASHQCDNFFQDNPMFEYRKLHLRDSPLEDISLVfEQVIEFIERAIACNGKIFIHCQMGVSRSSCLCMLWIMKTTRCSLEEASDLV ... | .|| .... . .. .. . | .|.... | . | ..... .| | . .. . .|| .|. |. | ...|. .. ..| |. avqfladqGirvlvslttegapyseaapsltlrridipdfcPPaleqv-arlvriveeaekkeeavgvhcalGlGrtGtllacylvkeeglaaddaiaev KQVRPI . |. rkrrkG |
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| Phosphatase | DDB_G0271860.AA | Subfamily.PTPDC1.PD | 406-460 | 31 | 1.9e-06 | 17.8 | In-house | 156-209 (229) | Show / Hide |
Range on Protein: 406-460 Range on HMM: 156-209/229 Sequence Identity: 31% (17 aa) VIEFIERAIaCNGKIFIHCQMGVSRSSCLCMLWIMKTTRCSLEEASDLVKQVRPI .. .. |. .||| .|| | | | ... ..| . ||| .||.. || ivkvvdfal-eegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrpk |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| DDB_G0271860.AA | Protein | None | 560 | None | Fasta, JSON |
| DDB_G0271860.NA | RNA | None | 1683 | None | Fasta, JSON |
| DDB_G0271860.AA.PD_337-491 | Protein Phosphatase Domain | None | 155 | None | Fasta, JSON |