Gene DDB_G0281963
DDB_G0281963
Species: D.discoideum
Alias: DDB_G0281963
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of DDB_G0281963.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | DDB_G0281963.AA | Family.DSP.PD | 2-152 | 36 | 6.9e-37 | 118.6 | In-house | 105-259 (387) | Show / Hide |
Range on Protein: 2-152 Range on HMM: 105-259/387 Sequence Identity: 36% (57 aa) NDVSRIFPGFYIGSLPAV-NRNTLDKYQITHVCSVLNEfQPKWTK--IYKYLHIDIYDSPSVDIMKYFDKTFQFIEEGR-KDGGVLVHCFAGISRSATIC ...|.|.|. |.||| |. |. | ....|.. .. . .|. || |||.| | |... .. ..|.| ..|||||. . | ||||| ||..||.|.. gkpseilphlylgsllaaknlewlkelgvtkivnltdd-kpqftkelgikylripidDhnapplenlfekaidfieegndskgvVlVHCkaGkgRsgtli IAYIMRKLNISFEDAHGLVSDARP-IIYPNESFIKQLKKYELILKKNRENPQIVEK |||.| . ....|.| .|...|| .| ||. |.||||..| . | .... .... iaYlmksegltleealdwvrskRpgvitpnqgflkqlkdlekeklkvssevmelrf |
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| Phosphatase | DDB_G0281963.AA | Subfamily.DSP12.PD | 4-139 | 46 | 9.4e-52 | 165.9 | In-house | 2-141 (143) | Show / Hide |
Range on Protein: 4-139 Range on HMM: 2-141/143 Sequence Identity: 46% (65 aa) VSRIFPGFYIGSLPAVN-RNTLDKYQITHVCSVLNEFQPKWTKIYKYLH--IDIYDSPSVDIMKYFDKTFQFIEEGR-KDGGVLVHCFAGISRSATICIA ||.| ||.|.|.|.||. |..|....||||.|| .| .|...|.... . |.|.|.|. |.....|....|||||. |.| ||||| ||.|||.||.|| vseilpglylggleavqerellkelkithvlsvikeelpelqkekgvkskliqilDepeedlLshldeavrFieeglekegavlvHClagvSRSvtiviA YIMRKLNISFEDAHGLVSDARPIIYPNESFIKQLKKYELI |.|.| ..|.|.|. ||..... |.|||.|..||| .| . YlmkkeklslekAlklvkekkkeiepNegFleQLklfekm |
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| Phosphatase | DDB_G0281963.AA | DSPc | 3-139 | 35 | 4.1e-46 | 160.44 | SMART | 1-172 (172) | Show / Hide |
Range on Protein: 3-139 Range on HMM: 1-172/172 Sequence Identity: 35% (61 aa) DVSRIFPGFYIGSLPAVN---RNTLDKYQITHVCSVLNEFQPKWTKI-----------------YKYLHID-IYD-------SPSVDIMKYFDKTFQFIE ..|.| |. |.|| |. . |.|..|||| .| .|. .. .. . |.|| | | .....| .||.....||. GPSEITPHLYLGSYPHHMEPNPCFLKKHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFIH EGRKDGG-VLVHCFAGISRSATICIAYIMRKLNISFEDAHGLV-----SDAR-PIIYPNESFIKQLKKYELI . |..|| |||||.||||||||.||||.|.. |.| .|| .| ..| |||.||..|..||. .| . DCRQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK |
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| Phosphatase | DDB_G0281963.AA | Subfamily.LRR-DSP.PD | 5-137 | 44 | 5.7e-44 | 140.3 | In-house | 3-135 (137) | Show / Hide |
Range on Protein: 5-137 Range on HMM: 3-135/137 Sequence Identity: 44% (59 aa) SRIFPGFYIGSLP-AVNRNTLDKYQITHVcSVLNEFQPKWTKIYKYLHIDIYDSPSVDIMKYFDKTFQFIEEGRKDGGVLVHCFAGISRSATICIAYIMR . | ...|.|.. | |.. | . ..||. . .|.| . ...||| ||| | . .||...|... ||.|||..||||.|| ||.|||||. |||.|. dliidklylgcresamnksilkdnnvthi-lavadfkplypdlfkyliidiedvdeadiyqhfkemnafidegrekggvlihcragvsrsatlviaylmk KLNISFEDAHGLVSDARPIIYPNESFIKQLKKYE | .. |..| || . || ||||. |..||||.| knslkfkealdlvikkrpriypnrgfldqlkkfe |
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| Phosphatase | DDB_G0281963.AA | Subfamily.DSP19.PD | 4-137 | 42 | 1.9e-42 | 135.4 | In-house | 2-137 (139) | Show / Hide |
Range on Protein: 4-137 Range on HMM: 2-137/139 Sequence Identity: 42% (58 aa) VSRIFPGFYIGSLPA-VNRNTLDKYQITHVCSVLNEFQPKWTKIYKYLHIDIYDSPSVDIMKYFDKTFQFIEEGRKD-GGVLVHCFAGISRSATICIAYI |... | .|.|| . ....|.| .|||. .| . . ..| ..|..|.|.| | .....|......||||.|. | ||||| ||.||||.. |||. vaevkprlylgsqdvaadkeilkklkitHilnvavgvpnvfpkdftyksieilDlpetkllsylkealdFieearskdgrvlvHCnAGvSRsasvviayl MRKLNISFEDAHGLVSDARPIIYPNESFIKQLKKYE |.. ..|.|.| | .||| | ||| ||||||.|| mkdeelslekalekvrearpcikPneGFikqLkeye |
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| Phosphatase | DDB_G0281963.AA | Subfamily.DSP1.PD | 5-137 | 38 | 1.1e-37 | 120.2 | In-house | 3-137 (139) | Show / Hide |
Range on Protein: 5-137 Range on HMM: 3-137/139 Sequence Identity: 38% (52 aa) SRIFPGFYIGS-LPAVNRNTLDKYQITHVCSVLNEFQPKWTKIYKYLHIDIYDSPSVDIMKYFDKTFQFIEEGRKDGG-VLVHCFAGISRSATICIAYIM ..| . .|.|| | |...|.. .||.. | .| . .. ...|| .| . |....||...|.. .||.. .| || ||||| |||||||||..||.| veildfLyLGsaehasnlqlLkelkitallnvsaelpnvfeelfkyksipvednkkadisslfeeaidfidsvkkkgGrvlvhCqaGisrsativlayLm RKLNISFEDAHGLVSDARPIIYPNESFIKQLKKYE .. ....|.|. | . | || || .|..|| ..| kekkvrleeafefvkqrrsiisPnfgfvgqLlefe |
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| Phosphatase | DDB_G0281963.AA | DSPc | 11-139 | 35 | 5.4e-37 | 130.55 | Pfam | 1-151 (151) | Show / Hide |
Range on Protein: 11-139 Range on HMM: 1-151/151 Sequence Identity: 35% (54 aa) FYIGSLPAVN--RNTLDKYQITHVCSVLNEFQPKWT---KIYKYLHID-IYD---------SPSVDIMKYFDKTFQFIEEGRKDGG-VLVHCFAGISRSA |.|| |... |.|..|||| .. .| . |. . . |..| . | .....| .||.. ..||. |..|| ||||| ||||||| LYLGSYPHHMADPAFLQKHGITHVINCTMECPNNWFYHNSHFHYMWIPHVHDHIHYYHIHWNHCTNISQYFPMATDFIDDCRQKGGKVLVHCQAGISRSA TICIAYIMRKLNISFEDAHGLV-----SDAR-PIIYPNESFIKQLKKYELI ..||||.|.. |.| ..| .| . | |.|.|| .|..|| || . CLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ |
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| Phosphatase | DDB_G0281963.AA | Subfamily.DSP15.PD | 4-137 | 39 | 1.2e-36 | 116.7 | In-house | 2-136 (138) | Show / Hide |
Range on Protein: 4-137 Range on HMM: 2-136/138 Sequence Identity: 39% (54 aa) VSRIFPGFYIGSLP-AVNRNTLDKYQITHVCSVLNEFQPKWTKiYKYLHIDIYDSPSVDIMKYFDKTFQFIEEGR-KDGGVLVHCFAGISRSATICIAYI .... ||.|.|.. | ... |....|||. |.... .| . ||| | . |||..|..|.|... .|| . | ..| |||||.|||||| |...||| mnkvlpGlyvGnfrdakdkeqleenkithilsihdsakplled-ikylcikaadsPdqdlskffkesidfihkcrleggnvlvhclaGisrsvtlvvayi MRKLNISFEDAHGLVSDARPIIYPNESFIKQLKKYE | ..|.||| | ||.. || | .||...| mtvtelswedalkavkaarsvanPnvGfrrqlqefe |
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| Phosphatase | DDB_G0281963.AA | Subfamily.DSP14.PD | 4-137 | 38 | 7.8e-36 | 114.2 | In-house | 2-136 (138) | Show / Hide |
Range on Protein: 4-137 Range on HMM: 2-136/138 Sequence Identity: 38% (52 aa) VSRIFPGFYIGSLPAVNRNTLDKYQITHVCSVLNEFQPKWTKIYKYLHIDIYDSPSVDIMKYFDKTFQFIEEGRKDGG-VLVHCFAGISRSATICIAYIM .|.| . |... |.....|.| .||.. | | . .. |...| . |.|. .....||.. . ||| .|.|| .|||| ||.||||....||.| lseitesLylsgaaalkkeklkkkkitlivnvttelpetkledvktvkikveDkpeaklaehfdevadkieevkkkgGktlvhCvaGvsRsAslvlaylm RKLNISFEDAHGLVSDARPIIYPNESFIKQLKKYE . ..| ..|. || .||||| || | ||| .|| kyeklsLreayklvksaRpiirPnvGFwkqlidyE |
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| Phosphatase | DDB_G0281963.AA | Subfamily.DSP10.PD | 4-137 | 38 | 1.2e-35 | 113.4 | In-house | 2-139 (141) | Show / Hide |
Range on Protein: 4-137 Range on HMM: 2-139/141 Sequence Identity: 38% (53 aa) VSRIFPGFYIGSL-PAVNRNTLDKYQITHVCSVLNEFQPKW--TKIYKYLHIDIYDSPSVDIMKYFDKTFQFIEEGRKDG-GVLVHCFAGISRSATICIA .|.|.| ...|. | ....||...|..| | .. .. .. .| .|.. ||. .. ..|.....|||| || | ||||| ||||||||. || assilpflllGnekdaadkdaldrlgikyvlnvttsvPnffeekglvrykripvsdsgkqnlkqkfeealefieearkrgsrvlvhchaGisrsatvvia YIMRKLNISFEDAHGLVSDARPIIYPNESFIKQLKKYE |.|. |..|...|. .| ..|||| || .|. || ..| yvmkhlslslseaykfvkekrPiisPnlnfmGqllefe |
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| Phosphatase | DDB_G0281963.AA | Subfamily.DSP6.PD | 6-137 | 39 | 1.4e-34 | 109.9 | In-house | 4-139 (141) | Show / Hide |
Range on Protein: 6-137 Range on HMM: 4-139/141 Sequence Identity: 39% (53 aa) RIFPGFYIGSL-PAVNRNTLDKYQITHVCSVLNEFQPKWTKIY--KYLHIDIYDSPSVDIMKYFDKTFQFIEEGRK-DGGVLVHCFAGISRSATICIAYI .| | .|.|| | |...|.|..| .| | .. . |. . ||..| | | | ...|.| ....||.|.|. . .|||||.||.||||...||.| eilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkykqipiedhlsqnlakffPeaiefidearskkskvlvhclaGvsrsvtvtlayl MRKLNISFEDAHGLVSDARPIIYPNESFIKQLKKYE .||..|..||. || . .. | || .|..||...| mkklalslndaydlvkkkksnisPnfnfmgqlldfe |
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| Phosphatase | DDB_G0281963.AA | Subfamily.Slingshot.PD | 5-137 | 40 | 1.8e-34 | 109.5 | In-house | 3-137 (139) | Show / Hide |
Range on Protein: 5-137 Range on HMM: 3-137/139 Sequence Identity: 40% (54 aa) SRIFPGFYIGS-LPAVNRNTLDKYQITHVCSVLNEFQPKWTKIYKYLHIDIYDSPSVDIMKYFDKTFQFIEEGRKDG-GVLVHCFAGISRSATICIAYIM |.|| |.|| | | . | . ..... | .| . . . .|||.| .||... |..|....|..|||. ...| ||||| |.||||.. ||| | skifdhlylGsewnasnleelkengveyilnvtkeidnffpekfkylnirvydeeetdllkhwnetykfiekakekgskvlvhckmGvsrsastviayam RKLNISFEDAHGLVSDARPIIYPNESFIKQLKKYE .. ..|.|.|. | . | || ||..|.||||.|| keyelsleealeyvkerrsiikpnkgflkqlkvye |
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| Phosphatase | DDB_G0281963.AA | Subfamily.DSP8.PD | 5-139 | 39 | 6.7e-32 | 101.5 | In-house | 3-141 (143) | Show / Hide |
Range on Protein: 5-139 Range on HMM: 3-141/143 Sequence Identity: 39% (54 aa) SRIFPGFYIGSLP-AVNRNTLDKYQITHVC--SVLNEFQPKWTKIYKYLHIDIYDSPSVDIMKYFDKTFQFIEEGRKD-GGVLVHCFAGISRSATICIAY || | |.|| ......|.|..|..| | . ... .| ..|.| . |. . ... .|||...||. |. | |||||.||||||||. |||| trilpnlylGsqkdsldeellkklgisyvlnisescpkdvellkesrflriPvkDkyeekllpwfdkalefidkarsangkvlvhclaGisrsatvaiay IMRKLNISFEDAHGLVSDARPIIYPNESFIKQLKKYELI |..|..|...|. | . || | || |. || .|| imktlemsldeayrfvkekrptispnlnflgqLleyeke |
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| Phosphatase | DDB_G0281963.AA | Subfamily.STYX.PD | 5-139 | 35 | 3.8e-27 | 86.0 | In-house | 3-146 (146) | Show / Hide |
Range on Protein: 5-139 Range on HMM: 3-146/146 Sequence Identity: 35% (50 aa) SRIFPGFYIGSLPAVNRNTLD---KYQITHVCSVLN-----EFQPKWTKIYKYLHIDIYDSPSVDIMKYFDKTFQFIEEGRKDGG-VLVHCFAGISRSAT |.||...| | . |. . |||. . . .|.. . ..|| .|. |.. .|..|. .. .||.. . || |||||||||||.. || qeilpglflgpysaamksklevlkehgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaa ICIAYIMRKLNISFEDAHGLVSDARPIIYPNESFIKQLKKYELI ||| . . .|. | . | | ||| |..|||.|| | lviayimetyglkyreafayvqerrfcinpnegfvsqlkeyeai |
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| Phosphatase | DDB_G0281963.AA | Subfamily.DSP3.PD | 4-136 | 35 | 7.4e-27 | 85.1 | In-house | 2-145 (148) | Show / Hide |
Range on Protein: 4-136 Range on HMM: 2-145/148 Sequence Identity: 35% (51 aa) VSRIFPGFYIGS-LPAVNRNTLDKYQITHVCSVLNEFQ-------P-KWTK-IYKYLHIDIYDSPSVDIMKYFDKTFQFIEEG--RKDGGVLVHCFAGIS | ..|. |.| | ... | | |||| .. . . ... ||| ... |.|..|. |||.. ..||.| .|.| ||||| .||| vdevypkvyvgdeavakdkekLkklGithvLnaaegkrllkvdtdaefYkdleikylGvevsDvpefdlskyfeeaadfidealsqkngkvlvhcvvGis RSATICIAYIMRKLNISFEDAHGLVSDARPiIYPNESFIKQLKKY ||||. .||.| . ... ..| | . | |.||| |.||| .. RsatlvlayLmirrkltlkeaiktvrkkre-ilPneGflkqLlel |
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| Phosphatase | DDB_G0281963.AA | Subfamily.STYXL1.PD | 30-137 | 32 | 3.2e-22 | 70.3 | In-house | 33-141 (143) | Show / Hide |
Range on Protein: 30-137 Range on HMM: 33-141/143 Sequence Identity: 32% (35 aa) THVCSVLNEFQPKWTKIYKYLHIDIYDSPSVDIMKYFDKTFQFIEEGRKDG-GVLVHCFAGISRSATICIAYIMRKLNISFEDAHGLVSDARPIIYPNES .|.| .... .... | |||.. |.. |... ... ||||. .|.| ||| ||||||.. |||.| . .|....|. . ... . || .|. vnvssdaekliagladvakllhiavedeneadllerlkevvqfiekhkkegevvlvfsnkGisrsaaviiaylmyskkitlkkaykylkkckenvkPnra FIKQLKKYE .||...| fveqlseWe |
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| Phosphatase | DDB_G0281963.AA | Subfamily.PTPMT1.PD | 24-136 | 25 | 1.5e-18 | 58.1 | In-house | 33-143 (146) | Show / Hide |
Range on Protein: 24-136 Range on HMM: 33-143/146 Sequence Identity: 25% (29 aa) LDKYQITHVCSVLNEFQPKWTKIYKYLHIDIYDSPSVDIMKyfdKTFQFIEEGRKDG-GVLVHCFAGISRSATICIAYIMRKLNISFEDAHGLVSDARPI . |....... .|.. . . ... .|. ..||.. .. .. .|||. ...| | ||| || .||||. ..|.|.| ..| |.|. .. . ||.| neeyelkalansteewkklGveqlqlatvDfteapslekle---egvefiekvaskgssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpq IYPNESFIKQLKKY ... .. |... irlkskqwralqef |
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| Phosphatase | DDB_G0281963.AA | Subfamily.CDC14.PD | 58-130 | 25 | 5.6e-08 | 23.8 | In-house | 182-251 (258) | Show / Hide |
Range on Protein: 58-130 Range on HMM: 182-251/258 Sequence Identity: 25% (19 aa) PSVDIMKYFDKTFQFIeegrkDGGVLVHCFAGISRSATICIAYIMRKLNISFEDAHGLVSDARP--IIYPNESFI || |.| | . . . .| . ||| ||. | .|. .|.... ... ... . . ||| .| | .... Psdailkkfleiteka-----eGaiavhCkaGLGrtgtligcylikhyrftaaetiawlriarPGsvigpqqtyl |
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| Phosphatase | DDB_G0281963.AA | Subfamily.RNGTT.PD | 56-135 | 30 | 8.2e-08 | 23.1 | In-house | 56-135 (140) | Show / Hide |
Range on Protein: 56-135 Range on HMM: 56-135/140 Sequence Identity: 30% (25 aa) DSPSVDIMKYFDKTFQFIEEGRKDGGVLVHCFAGISRSATICIAYIMRKLNISFEDAHGLVSDARPI-IYPNEsFIKQLKK ..|. . .| | | . . . | . ||| | | . .||.. |...| |.| | . ||| || .. ..|.| | eaPtkeqtklfiklvkeflkkkPdevigvhCthGfnrtGflivayLvekedwsveaavalfakarppGiyked-ylkelfk |
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| Phosphatase | DDB_G0281963.AA | Subfamily.DSP23.PD | 47-121 | 21 | 1.1e-07 | 23.1 | In-house | 36-108 (128) | Show / Hide |
Range on Protein: 47-121 Range on HMM: 36-108/128 Sequence Identity: 21% (16 aa) YKYLHIDIYDSPSVDIMKYFDKTFQFIEegRKDGGVLVHCFAGISRSATICIAYIMRKLNISFEDAHGLVSDARP .. ..|. . |... .. . . . | .|.. | ||| |. |. |. |.... ... .|| | |. lrridipdfcPPaleqvarlvriveeae--kkeeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrrk |
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| Phosphatase | DDB_G0281963.AA | Subfamily.PTPDC1.PD | 55-140 | 23 | 3.3e-07 | 21.0 | In-house | 145-227 (229) | Show / Hide |
Range on Protein: 55-140 Range on HMM: 145-227/229 Sequence Identity: 23% (20 aa) YDSPSVDIMKYFDKTFQFIEegrKDGGVLVHCFAGISRSATICIAYIMRKLNISFEDAHGLVSDARPIIYPNESFIKQLKKYELIL |...|.. . | .| ..| . ||| || | . .|.. . ... |.| || . || . .. .....|.| ygvasleriLdivkvvdfal---eegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrpksiqtreqvelveeFalfl |
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| Phosphatase | DDB_G0281963.AA | Subfamily.DSP11.PD | 58-136 | 27 | 3.9e-07 | 21.0 | In-house | 58-138 (141) | Show / Hide |
Range on Protein: 58-136 Range on HMM: 58-138/141 Sequence Identity: 27% (22 aa) PSVDIMKYFD-KTFQFIEEGRK-DGGVLVHCFAGISRSATICIAYIMRKLNISFEDAHGLVSDARPIIYPNESFIKQLKKY |. ...| | . .|.|. . | . ||| |. |. . |.. . ..| ||| ..|| | ....||| pekedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyspedaieafeearGhslerenyledLkkl |
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| Phosphatase | DDB_G0281963.AA | Subfamily.R_Nematode_3.PD | 80-101 | 55 | 1.2e-06 | 19.1 | In-house | 199-220 (267) | Show / Hide |
Range on Protein: 80-101 Range on HMM: 199-220/267 Sequence Identity: 55% (11 aa) GGVLVHCFAGISRSATICIAYI |.|||..|||||||. . . tpvvVHCsdGisRsatlaaiel |
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| Phosphatase | DDB_G0281963.AA | Subfamily.N_Nematode_1.PD | 71-105 | 45 | 4.5e-06 | 17.2 | In-house | 187-223 (265) | Show / Hide |
Range on Protein: 71-105 Range on HMM: 187-223/265 Sequence Identity: 45% (17 aa) QFIEEGRK-DGGVLVHCFAGISRSATI-CIAYIMRKL ...|. |. | ..||| ||| |. || |.||. || elleavrgskgPivvhCsaGiGrtGtivaieyildkl |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| DDB_G0281963.AA | Protein | None | 394 | None | Fasta, JSON |
| DDB_G0281963.NA | RNA | None | 1185 | None | Fasta, JSON |
| DDB_G0281963.AA.PD_3-141 | Protein Phosphatase Domain | None | 139 | None | Fasta, JSON |