• Phosphatome.Net

Gene DDB_G0272662

DDB_G0272662
Species: D.discoideum
Alias: DDB_G0272662
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: PRL
Protein domain

Protein domains of DDB_G0272662.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase DDB_G0272662.AA Subfamily.PRL.PD 17-155 50 3.5e-65 209.4 In-house 1-139 (140) Show / Hide 
Range on Protein: 17-155
Range on HMM: 1-139/140
Sequence Identity: 50% (71 aa)

HKFILFDEPTEETIPYFKDLMKKNSCINIVRCCEINYDASLF--EGVKIHELCFKDGNVPPKDIIERWLEILKQAFIENgkQKTTVGIHCIAGLGRTPLL
..|...|||..||...|.. .||......||.||..|||. .  ||.....|.|.||.||||.....|||.||..| |.  .|.||..||.|||||.|.|
lrflildepsdetvekfieelkkenvkevvrvcepsydaeklkeegievldlafddGavPpkevvdeWlellkekfkee--pkstvavhcvaGlGraPvl

VCIALIEDGMKPLQAVEFVRSKRKNAINSPQIKFLKEYKAS
|..||||.|||. .||||.|.||..|||| |.|||..|||.
valalieaGmkyedavefirekrrgainskqlkflekykak
Phosphatase DDB_G0272662.AA Family.DSP.PD 26-157 27 2.9e-23 74.1 In-house 119-245 (387) Show / Hide 
Range on Protein: 26-157
Range on HMM: 119-245/387
Sequence Identity: 27% (38 aa)

TEETiPYFKDLmKKNSCINIVRCCeinYDASLF---EGVKIHELCFKDGNVPPKDIIerWLEILKqaFIENGK-QKTTVGIHCIAGLGRTPLLVCIALIE
..     .. | |..    ||...   .| . |   .|.|.... . |.|.|| ...  . ....  |||.|. .| .| .|| ||.||.. |...|.. 
llaa-knlewl-kelgvtkivnlt---ddkpqftkelgikylripidDhnapplenl--fekaid--fieegndskgvVlVHCkaGkgRsgtliiaYlmk

D-GMKPLQAVEFVRSKRK-NAINSPQikFLKEYKASKK
 |..  .|...|||||. ... . .  |||..|.  | 
segltleealdwvrskRpgvitpnqg--flkqlkdlek
Phosphatase DDB_G0272662.AA Subfamily.CDC14.PD 29-154 31 2.1e-20 64.8 In-house 139-256 (258) Show / Hide 
Range on Protein: 29-154
Range on HMM: 139-256/258
Sequence Identity: 31% (40 aa)

TIPYFkdlmKKNSCINIVRCCEINYDASLFE--GVKIHELCFKDGNVPPKDIIERWLEILKQAfiengkqKTTVGIHCIAGLGRTPLLV-CIALIEDGMK
. ||    .||   .|||  .  |||. |.  |.. ..| | || ||.. |....|||. .|       . .. .|| ||||||  |. |... ...  .
lleyf----rknnvttivrLnkklYdakkftdaGfahlDlffiDGtvPsdailkkfleiteka-------eGaiavhCkaGLGrtgtligcylikhyrft

PLQAVEFVRSKRKNAINSPQIKFLKEYKA
.. ..|  |   . .|| ..|.| .|   
aaetiawlriarPGsvigpqqtylvekqa
Phosphatase DDB_G0272662.AA Subfamily.PTPDC1.PD 59-154 28 5.6e-15 46.7 In-house 133-225 (229) Show / Hide 
Range on Protein: 59-154
Range on HMM: 133-225/229
Sequence Identity: 28% (28 aa)

EGVKIHELCFKDGNVPPkdiIERWLEILKqaFIENGKQKTTVGIHCIAGLGRTPLLVCIALI-EDGMKPLQAVEFVRSKRKNAINS-PQIKFLKEYKA
.|. ..   .|| .|..   .|| |.| |   ..   ..  ...|| |||||| .|..  |.  . ... .|...||||| ..|..  |.....|.. 
qgiyfynfglkDygvas---leriLdivk--vvdfaleegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrpksiqtreqvelveeFal
Phosphatase DDB_G0272662.AA Subfamily.DSP23.PD 57-155 30 2.3e-12 38.4 In-house 30-126 (128) Show / Hide 
Range on Protein: 57-155
Range on HMM: 30-126/128
Sequence Identity: 30% (30 aa)

LFEGVKIHELCFKDGNVPPKDIIERWLEILKQAfienGKQKTTVGIHCIAGLGRTP-LLVCIALIEDGMKPLQAVEFVRSKRKNAINS-PQIKFLKEYKA
... .. .  .|   |  . ..|...|...|     |.. .||.||. |||||  || |  . |.|.   .|.  || .|| .|..  || .|.|. .  
aapsltlrridipdfcPPaleqvarlvriveea----ekkeeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrrkGsietveqekavkdyee

S
 
y
Phosphatase DDB_G0272662.AA Subfamily.PTEN.PD 26-140 23 8.9e-12 36.3 In-house 27-139 (305) Show / Hide 
Range on Protein: 26-140
Range on HMM: 27-139/305
Sequence Identity: 23% (27 aa)

TEETIPYFKDLMKKNSCINIVrCCEINYDASLFEGvKIHELCFKDGNVPPKDIIERWLEILKQaFIENGKqKTTVGIHCIAGLGRTPLLVCIALIEDGMK
..... ...   |..  ..|. ... ... | |.| ....  |.| | |. ...|.  | ... .... | .  | .|| || ||| ...||.. |.|. 
slddlillltvykgkgklril-nargekedsdfdg-rvavypfdDhnpptleLleeivedvdk-wLkedk-snVvavHCkaGkGRtGvmicayLlksgik

PLQ--AVEFVRSKRKNA
.  |...  .|| .   
ksadealaiydekRtkd
Phosphatase DDB_G0272662.AA Subfamily.DSP11.PD 60-142 29 9.9e-12 36.2 In-house 44-127 (141) Show / Hide 
Range on Protein: 60-142
Range on HMM: 44-127/141
Sequence Identity: 29% (25 aa)

GVKIHELCFKDGNVPPKDIIERWLEILKQAFIENGKQKTTVGIHCIAGLGRTPLLVCIALIE-DGMKPLQAVEFVRSKRKNAIN
||| . |     .|| |...... | .|.   .| .... .|.||  |. ||  |.|  ||. .|..| .|.|   . |  ...
gvkykklncpGhevpekedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyspedaieafeearGhsle
Phosphatase DDB_G0272662.AA Subfamily.PTPMT1.PD 59-153 27 1.6e-10 32.3 In-house 51-144 (146) Show / Hide 
Range on Protein: 59-153
Range on HMM: 51-144/146
Sequence Identity: 27% (27 aa)

EGVKIHELCFKDG-NVPPKDIIERWLEILKQAFiengKQKTTVGIHCIAGLGRTPLLVCIALI-EDGMKPLQAVEFVRSKRKNA-INSPQIKFLKEYK
.||.  .|  .|  ..| .. .|. .|....      ... .| .|| || .|   ||   |. .  ..| .||.|...||..  ..| |.. |.|.|
lGveqlqlatvDfteapslekleegvefiekva----skgssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpqirlkskqwralqefk
Phosphatase DDB_G0272662.AA Subfamily.RNGTT.PD 53-151 29 3.1e-09 28.0 In-house 34-132 (140) Show / Hide 
Range on Protein: 53-151
Range on HMM: 34-132/140
Sequence Identity: 29% (30 aa)

YDASLF--EGVKIHEL-CFKDGNVPPKDIIERWLEILKQaFIENgKQKTTVGIHCIAGLGRTPLLVCIALIEDGMKPLQ-AVEFVRSKRKNAINSPQikF
||.. .  |||| ..| |   |. | |. .. .... |. |... | ....|.||  |  || .|..  |.|     .. ||.   . |..|   .  .|
ydkeelekegvkyiklqcrGrGeaPtkeqtklfiklvke-flkk-kPdevigvhCthGfnrtGflivayLvekedwsveaavalfakarppGiyked--y

LKE
|| 
lke
Phosphatase DDB_G0272662.AA Subfamily.LRR-DSP.PD 73-150 32 4.1e-09 27.7 In-house 55-129 (137) Show / Hide 
Range on Protein: 73-150
Range on HMM: 55-129/137
Sequence Identity: 32% (26 aa)

VPPKDIIERWLEIlkQAFIENGKQKTTVGIHCIAGLGRTPLLV-CIALIEDGMKPLQAVEFVRSKRKNAInsPQIKFLK
|.  || . . |.  .|||..|..|  | ||| ||. |.  || .  . .. .|  .|...| .|| .    |.. ||.
vdeadiyqhfkem--nafidegrekggvlihcragvsrsatlviaylmkknslkfkealdlvikkrpriy--pnrgfld
Phosphatase DDB_G0272662.AA Subfamily.DSP1.PD 75-151 31 9.2e-09 26.8 In-house 58-132 (139) Show / Hide 
Range on Protein: 75-151
Range on HMM: 58-132/139
Sequence Identity: 31% (24 aa)

PKDIIERWLEILKqaFIENGK-QKTTVGIHCIAGLGRTPLLVCIALI-EDGMKPLQAVEFVRSKRKnaINSPQIKFLKE
.|| ... |...  ||.. | ..  | .|| ||. |.  .| . |. |. ..  .| |||...|.  | || . |..  
kadisslfeeaid--fidsvkkkgGrvlvhCqaGisrsativlayLmkekkvrleeafefvkqrrs--iisPnfgfvgq
Phosphatase DDB_G0272662.AA Subfamily.DSP19.PD 75-153 32 1.6e-08 25.9 In-house 58-137 (139) Show / Hide 
Range on Protein: 75-153
Range on HMM: 58-137/139
Sequence Identity: 32% (26 aa)

PKDIIERWLEIlkQAFIENGKQK-TTVGIHCIAGLGRTPLLVCIALIEDGMKP-LQAVEFVRSKRKNA-INSPQIKFLKEYK
..... . |.  . |||....|  .| .|| ||  |.. .|   |..|  .   .|.| ||..|...  |.  || ||||. 
etkllsylkea--ldFieearskdgrvlvHCnAGvSRsasvviaylmkdeelslekalekvrearpcikPneGFikqLkeye
Phosphatase DDB_G0272662.AA Subfamily.DSP12.PD 74-155 25 2.1e-08 25.7 In-house 59-141 (143) Show / Hide 
Range on Protein: 74-155
Range on HMM: 59-141/143
Sequence Identity: 25% (22 aa)

PPKDIIERwLEILkQAFIENGK-QKTTVGIHCIAGLGRTPLlVCIALI--EDGMKPLQAVEFVRSKRKNA-INSPQIKFLKEYKAS
| .|...  |.    .|||.|  .. .| .|| ||. |    ..|| .  .....  .|...|..|.|..  |.  .. || ....
peedlLsh-ldea-vrFieeglekegavlvHClagvSRSvt-iviAYlmkkeklslekAlklvkekkkeiepNegFleQLklfekm
Phosphatase DDB_G0272662.AA Subfamily.DSP3.PD 47-151 25 1.8e-07 22.5 In-house 39-144 (148) Show / Hide 
Range on Protein: 47-151
Range on HMM: 39-144/148
Sequence Identity: 25% (28 aa)

RCCEINYDASLFEGVKIHELCFKDGNVPPKDIIERWLEIlkQAFIENG--KQKTTVGIHCIAGLGRTPLLVCI-ALIEDGMKPLQAVEFVRSKRKNAINS
|. ... ||. .....|. | ..  .||  |. . . |     ||..   .... | .|| .|. |.. ||    .|   ..  .|.. ||.||.   |.
rllkvdtdaefYkdleikylGvevsDvpefdlskyfeea--adfidealsqkngkvlvhcvvGisRsatlvlayLmirrkltlkeaiktvrkkreilPne

PQIKFLKE
  .| | |
GflkqLle
Phosphatase DDB_G0272662.AA Subfamily.R_Nematode_3.PD 95-145 27 1.8e-07 22.1 In-house 196-253 (267) Show / Hide 
Range on Protein: 95-145
Range on HMM: 196-253/267
Sequence Identity: 27% (16 aa)

KQKTTVGIHCIAGLGRTPLLVCIALI-------EDGMKPLQAVEFVRSKRKNAINSPQ
| ||.| .||..| .|.  |..| |        .. .. |. .. .|..|..||....
ksktpvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtel
Phosphatase DDB_G0272662.AA Subfamily.DSP10.PD 89-149 30 3.7e-07 21.4 In-house 72-132 (141) Show / Hide 
Range on Protein: 89-149
Range on HMM: 72-132/141
Sequence Identity: 30% (19 aa)

AFIENGKQK-TTVGIHCIAGLGRTPLLVCIALIE-DGMKPLQAVEFVRSKRknAINSPQIKFL
.|||. ... ..| .|| ||. |.  .|   ...  ..   .| .||..||   | || . |.
efieearkrgsrvlvhchaGisrsatvviayvmkhlslslseaykfvkekr--PiisPnlnfm
Phosphatase DDB_G0272662.AA Subfamily.Slingshot.PD 59-152 29 6.9e-07 20.5 In-house 44-133 (139) Show / Hide 
Range on Protein: 59-152
Range on HMM: 44-133/139
Sequence Identity: 29% (27 aa)

EGVKIHELCFKDgnVPPKDIIERWLEILKqaFIENGKQ-KTTVGIHCIAGLGRTPLL-VCIALIEDGMKPLQAVEFVRSKRKnaINSPQIKFLKEY
| .| ...   |   . .|... | |  |  |||. |. .. | .||  |. |.    .  |. | ...  .|.|.|...|.  ||   |||    
ekfkylnirvyd--eeetdllkhwnetyk--fiekakekgskvlvhckmGvsrsastviayamkeyelsleealeyvkerrs--iikpnkgflkql
Phosphatase DDB_G0272662.AA Subfamily.DSP6.PD 89-151 28 7.5e-07 20.3 In-house 72-134 (141) Show / Hide 
Range on Protein: 89-151
Range on HMM: 72-134/141
Sequence Identity: 28% (18 aa)

AFIENGKQK-TTVGIHCIAGLGRTPLLVCIALIEDGMKPL-QAVEFVRSKRKNAinSPQIKFLKE
.||.....| ..| .||.||. |.  ..   |..  .  | .| ..|..|. |   ||  .|.. 
efidearskkskvlvhclaGvsrsvtvtlaylmkklalslndaydlvkkkksni--sPnfnfmgq
Phosphatase DDB_G0272662.AA Subfamily.DSP8.PD 40-150 26 1.4e-06 19.6 In-house 29-133 (143) Show / Hide 
Range on Protein: 40-150
Range on HMM: 29-133/143
Sequence Identity: 26% (30 aa)

NSCINIVRCCEINydASLFEGVKIHELCFKDGNvppKDIIERWLEIlKQAFIENGKQ-KTTVGIHCIAGLGRTPLlVCIALIED--GMKPLQAVEFVRSK
.  .|| . |...   .| . .... .  || .   .. .  |..     ||.  .. ...| .|| ||  |..  | || |     |.  .| .||..|
syvlnisescpkd--vellkesrflriPvkDky---eekllpwfdk-alefidkarsangkvlvhclaGisrsat-vaiayimktlemsldeayrfvkek

RkNAInSPQIKFLK
| ..| ||...|| 
r-pti-spnlnflg
Phosphatase DDB_G0272662.AA Subfamily.N12.PD 45-125 19 1.5e-06 18.9 In-house 149-227 (270) Show / Hide 
Range on Protein: 45-125
Range on HMM: 149-227/270
Sequence Identity: 19% (16 aa)

IVRCCEINYDASLFEGVKIHELCFKDGNVPPKdiIERWLEILKQAFIENGKQKTTVGIHCIAGLGRTPLLVCIALIEDGMK
..|. ... .    .  ..|   . | .|| .  ... ||.....   ...... . .|| || |||  .. | .. . .|
lirtLkveaqkesrkvyqfhytaWPDhgvPss--aksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellk
Phosphatase DDB_G0272662.AA PTPc_motif 59-156 17 2e-06 22.45 SMART 1-92 (92) Show / Hide 
Range on Protein: 59-156
Range on HMM: 1-92/92
Sequence Identity: 17% (18 aa)

EGVKIHELCFKDG-----NVPPKDIIERWLEILKQAFIENGKQKTTVGIHCIAGLGRTPLLVCIALIEDGMKPLQAVEFVRSKRKNAINSPQIKFLKEYK
.    | .  .|      .||  | | .... ...           . .|| || |||  ...| .. . .  .| |. .|. | ... . .      . 
TVHHYHYTNWPDHVEKDSGVPE-DSILEFIRHVRK----------PIVVHCSAGCGRTGTFCAIDMMMQQVDIFQTVKEMRKQRPGMVQTEEQYIFCYRC

ASK
  .
ILE
Phosphatase DDB_G0272662.AA Subfamily.N_Nematode_1.PD 83-129 32 2.2e-06 18.5 In-house 186-228 (265) Show / Hide 
Range on Protein: 83-129
Range on HMM: 186-228/265
Sequence Identity: 32% (15 aa)

LEILKQAfienGKQKTTVGIHCIAGLGRTPLLVCIALIEDGMKPLQA
||.|...     ..|. . .|| ||.|||  .| |..| | .   . 
lelleav----rgskgPivvhCsaGiGrtGtivaieyildkllegkq
Phosphatase DDB_G0272662.AA Subfamily.TPIP.PD 65-139 23 2.4e-06 18.6 In-house 7-81 (245) Show / Hide 
Range on Protein: 65-139
Range on HMM: 7-81/245
Sequence Identity: 23% (18 aa)

ELCFKDGNVPPKDIIERWLEILKQaFIENGkQKTTVGIHCIAGLGRTPLLVCIALIEDGMK--PLQAVEFVRSKRKN
.   | |||  . .  . . .|. ....  ..  | |||  | |||  .||  ||. ..     .....  ..| . 
rimiddhnvPtleelvvftkevke-wlakd-lenvvaihckGGkgrtGtivcalliaseifltaeesldyfgerrtd
Phosphatase DDB_G0272662.AA Subfamily.N_Nematode_4.PD 82-140 26 2.7e-06 18.2 In-house 183-245 (264) Show / Hide 
Range on Protein: 82-140
Range on HMM: 183-245/264
Sequence Identity: 26% (17 aa)

WLEILKqaFIENGKQKTTVGIHCIAGLGRTPLLVCIALIEDGMKP------LQAVEFVRSKRKNA
....|   . . |... . .|| ||.|||  || | . .  ..       |. |  .|. | .| 
viklyk--avkkkkkekPivvhcsaGvGrtatlvGidyatirirenseievldivrelramrlka
Phosphatase DDB_G0272662.AA Subfamily.N3.PD 68-148 29 3.2e-06 17.9 In-house 166-251 (261) Show / Hide 
Range on Protein: 68-148
Range on HMM: 166-251/261
Sequence Identity: 29% (26 aa)

FKDGNVPPKDiiERWLEILKQAFIENGKQKTTVGIHCIAGLGRTPLLVC----IALIED--GMKPLQAVEFVRSKRKNAINS-PQIKF
. | .|| .   .  ||....       ... | .|| ||.||| .|.     .||||    . ||. |  .| .|.. ...  | ||
WpdhgvPdds--adflefvervrklrsgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtvsqykf
Sequence
Name Sequence Type Origin Length Description Download
DDB_G0272662.AA Protein None 163 None Fasta, JSON
DDB_G0272662.NA RNA None 492 None Fasta, JSON
DDB_G0272662.AA.PD_10-157 Protein Phosphatase Domain None 148 None Fasta, JSON