Gene DDB_G0292024
DDB_G0292024
Species: D.discoideum
Alias: DDB_G0292024
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of DDB_G0292024.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | DDB_G0292024.AA | Subfamily.PRL.PD | 20-159 | 54 | 2.1e-68 | 219.7 | In-house | 1-140 (140) | Show / Hide |
Range on Protein: 20-159 Range on HMM: 1-140/140 Sequence Identity: 54% (76 aa) HRFLIFDAPNDDNLPLYINELKKYNVSHLVRACDPTYSTEPLQAIGIQVHDMPFADGGSPPDAVVNNWIKILGESYKKDSKETIGIHCVAGLGRAPVLVA .||||.|.|.|.... .|.||||.||...||.|.|.|..| |.. ||.|.|..|.||..||..||..|...| |..|...|.|...|||||||||||||| lrflildepsdetvekfieelkkenvkevvrvcepsydaeklkeegievldlafddGavPpkevvdeWlellkekfkeepkstvavhcvaGlGraPvlva IALIEGGMNPLQAVEYIRERRRGSINIKQIQYLKNYKSKK .|||| ||.. .|||.|||.|||.|| ||...|..||.|| lalieaGmkyedavefirekrrgainskqlkflekykakk |
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| Phosphatase | DDB_G0292024.AA | Subfamily.CDC14.PD | 36-156 | 27 | 1.1e-21 | 68.8 | In-house | 139-255 (258) | Show / Hide |
Range on Protein: 36-156 Range on HMM: 139-255/258 Sequence Identity: 27% (33 aa) YINELKKYNVSHLVRACDPTYSTEPLQAIGIQVHDMPFADGGSPPDAVVNNWIKILGESykkdsKETIGIHCVAGLGRAPVLVAIALIE-GGMNPLQAVE ... .| ||...|| | . ...|.. .|. |.||. |.||.......|. .. . .| .|| ||||| .|.. ||... ... ..| lleyfrknnvttivrLnkklYdakkftdaGfahlDlffiDGtvPsdailkkfleiteka-----eGaiavhCkaGLGrtgtligcylikhyrftaaetia YIRERRRGSINIKQIQYLKNYK | ||. .| .||.. . wlriarPGsvigpqqtylvekq |
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| Phosphatase | DDB_G0292024.AA | Family.DSP.PD | 37-160 | 27 | 6.5e-21 | 66.2 | In-house | 125-248 (387) | Show / Hide |
Range on Protein: 37-160 Range on HMM: 125-248/387 Sequence Identity: 27% (34 aa) INELKKYNVSHLVRACDPTYS-TEplqAIGIQVHDMPFADGGSPPDAVVnnWIKILGeSYKK--DSKETIGIHCVAGLGRAPVLVAIALIEG-GMNPLQA .||...|.. |...| . |. ||.....|. |...|| . . ..|.. .. |||... .|| ||.|| ..|... |.. |...|.... lewlkelgvtkivnltddkpqftk---elgikylripidDhnapplenl--fekaid-fieegndskgvVlVHCkaGkgRsgtliiaYlmksegltleea VEYIRERRRGSINIKQ--IQYLKNYKSKKK |..|.|.|. .| ...|| . ..| ldwvrskRpgvitpnqgflkqlkdlekekl |
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| Phosphatase | DDB_G0292024.AA | Subfamily.PTPDC1.PD | 55-156 | 25 | 2.5e-15 | 47.7 | In-house | 124-224 (229) | Show / Hide |
Range on Protein: 55-156 Range on HMM: 124-224/229 Sequence Identity: 25% (26 aa) TYSTEPLQAIGIQVHDMPFADGGSPPDAVVNNWIKILGESYkkdSKETIGIHCVAGLGRAPVLVAIALI-EGGMNPLQAVEYIRERRRGSINIK-QIQYL .|. | |. || .. ....| |... . . .|.. . .. |..|| ||||| ||.| |. ... .|.. .|..| ||. . |.. . sYdpeelmrqgiyfynfglkDygvasleriLdivkvvdfal---eegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrpksiqtreqvelv KNYK .... eeFa |
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| Phosphatase | DDB_G0292024.AA | Subfamily.DSP23.PD | 65-157 | 30 | 2.7e-13 | 41.3 | In-house | 33-125 (128) | Show / Hide |
Range on Protein: 65-157 Range on HMM: 33-125/128 Sequence Identity: 30% (29 aa) GIQVHDMPFADGGSPPDAVVNNWIKILGESYKKDskETIGIHCVAGLGRAPVLVAIALIE-GGMNPLQAVEYIRERRRGSINI-KQIQYLKNYKS .. .. . | | |.....|. |..||. |..|.||. ||||. |.| |.. |. .|. .|.||.|||. .| . .|.|. sltlrridipdfcPPaleqvarlvriveeaekke--eavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrrkGsietveqekavkdyee |
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| Phosphatase | DDB_G0292024.AA | Subfamily.PTPMT1.PD | 41-157 | 23 | 8.4e-11 | 33.1 | In-house | 22-145 (146) | Show / Hide |
Range on Protein: 41-157 Range on HMM: 22-145/146 Sequence Identity: 23% (29 aa) KKYNVSHLVRACDPT------YSTEPLQAIGIQVHDMPFADGGS-PPDAVVNNWIKILGESYKKdsKETIGIHCVAGLGRAPVLVAIALI-EGGMNPLQA .|.|| .| .. ||| .. |.. .. | . | . ... .... . .| .... .|| || .|. ||| |.. ..| .|| ekenvkavvslneeyelkalansteewkklGveqlqlatvDfteapslekleegvefiekvask--gssvYvHCkAGrtRsatlvacylmkkkklspeea VEYIRERRRgSINI--KQIQYLKNYKS ......|. | . ||.. |...|. vkflkkkRp-qirlkskqwralqefke |
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| Phosphatase | DDB_G0292024.AA | Subfamily.RNGTT.PD | 55-158 | 27 | 4.2e-10 | 30.7 | In-house | 33-136 (140) | Show / Hide |
Range on Protein: 55-158 Range on HMM: 33-136/140 Sequence Identity: 27% (28 aa) TYSTEPLQAIGIQVHDMPFA-DGGSPPDAVVNNWIKILGESYKKDSKETIGIHCVAGLGRAPVLVAIALIEGGMNPLQ-AVEYIRERRRGSINIKQiqYL | | |. |.. . . . | .| ....||. | .|| .|.||.|| | |. |.. |.| .. ||. . || .. |||.. yydkeelekegvkyiklqcrGrGeaPtkeqtklfiklvkeflkkkPdevigvhCthGfnrtGflivayLvekedwsveaavalfakarppGiyked--yl KNYKSK .. kelfkr |
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| Phosphatase | DDB_G0292024.AA | Subfamily.PTEN.PD | 59-140 | 25 | 2.1e-09 | 28.3 | In-house | 58-136 (305) | Show / Hide |
Range on Protein: 59-140 Range on HMM: 58-136/305 Sequence Identity: 25% (19 aa) EplqaiGIQVHDMPFADGGSPPDAVVNNWIKILGESYKKDSKETIGIHCVAGLGRAPVLVAIALIEGGMNPLQ--AVEYIRERR .|. .|| | .|. .... .. . . |.|... . .|| || ||. |... |.. |. . . |... | | f-----dgrvavypfdDhnpptleLleeivedvdkwLkedksnVvavHCkaGkGRtGvmicayLlksgikksadealaiydekR |
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| Phosphatase | DDB_G0292024.AA | Subfamily.DSP11.PD | 55-159 | 25 | 6.3e-09 | 27.0 | In-house | 34-139 (141) | Show / Hide |
Range on Protein: 55-159 Range on HMM: 34-139/141 Sequence Identity: 25% (27 aa) TYSTEPLQAIGIQVHDMPFADGGSPPDAVVNNWIKILGESY--KKDSKETIGIHCVAGLGRAPVLVAIALIE-GGMNPLQAVEYIRERRrGSiNIKQIQY |... |.. |.. . . . | . .|..... . | .||... ||.|| |. |. |. ||. |..| .|.| | | |.. . .||.. yykkkeltdegvkykklncpGhevpekedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyspedaieafeear-Gh-slereny LKNYKSKK | .. ledLkkla |
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| Phosphatase | DDB_G0292024.AA | Subfamily.N13.PD | 97-157 | 31 | 3e-07 | 21.4 | In-house | 188-253 (259) | Show / Hide |
Range on Protein: 97-157 Range on HMM: 188-253/259 Sequence Identity: 31% (21 aa) KDSKETIGIHCVAGLGRAPVLVAIALIEGGM------NPLQAVEYIRERRRGSINIKQiQYLKNYKS .... | .|| ||.||. ||..| . | . . . |. .||.|.| . |. ||. ||. qtdagPivvhcsaGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkd-qyifvyka |
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| Phosphatase | DDB_G0292024.AA | Subfamily.DSP3.PD | 50-149 | 18 | 5.7e-07 | 20.7 | In-house | 44-139 (148) | Show / Hide |
Range on Protein: 50-149 Range on HMM: 44-139/148 Sequence Identity: 18% (18 aa) RACDPTYSTEPLQAIGIQVHDMPFADGgsppDAVVNNWIKILGESYKKdSKETIGIHCVAGLGRAP-VLVAIALIEGGMNPLQAVEYIRERRRGSINIKQ .. . |. .. .|..|.|.| .| .. .. . . |. .. .. . .|||.|. |.. . .| .| .. .|.. .|..|| . dtdaefYkdleikylGvevsDvpefdl----skyfeeaadfidealsq-kngkvlvhcvvGisRsatlvlayLmirrkltlkeaiktvrkkreilPneGf I l |
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| Phosphatase | DDB_G0292024.AA | Subfamily.N12.PD | 66-124 | 25 | 6.6e-07 | 19.9 | In-house | 165-223 (270) | Show / Hide |
Range on Protein: 66-124 Range on HMM: 165-223/270 Sequence Identity: 25% (15 aa) IQVHDMPFADGGSPPDA-VVNNWIKILgESYKKDSKETIGIHCVAGLGRAPVLVAIALIE | | . . | | | | . . |. . ......... . .|| || ||. ...|| .. yqfhytaWPDhgvPssaksllelielv-relqesedaPlvvhCsaGvGrtGtiiaidyvr |
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| Phosphatase | DDB_G0292024.AA | Subfamily.N_Nematode_1.PD | 75-152 | 32 | 9.4e-07 | 19.5 | In-house | 175-254 (265) | Show / Hide |
Range on Protein: 75-152 Range on HMM: 175-254/265 Sequence Identity: 32% (28 aa) DGGSPPDAVvnNWIKILGEsyKKDSKETIGIHCVAGLGRAPVLVAIALIEGGMNPL-------QAVEYIRERRRGSINiKQIQYL | | || . ...| . . ||. | .|| ||.||. .|||..| . . |. |||.|. || ...||| drGvPpadl--aalellea--vrgskgPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiq-tdaqyl |
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| Phosphatase | DDB_G0292024.AA | Subfamily.R_Anemone_2.PD | 50-151 | 23 | 1.3e-06 | 19.4 | In-house | 143-250 (262) | Show / Hide |
Range on Protein: 50-151 Range on HMM: 143-250/262 Sequence Identity: 23% (26 aa) RACDPTYSTEPLQAIGIQVHDMPFADGGSPPDAvvNNWIKILGESYKKD---SKETIGIHCVAGLGRAPVLVAIALI------EGGMNPLQAVEYIRERR | . . |. . . | | ..| |.| .. . ....... | . ....| .|| ||.||. | .|. . |... .| |. .||.| rsfkvkrteeeeerqvrqfhytsWpdegvpesg--aslldlvrqvekaqqesgagpivvhcsaGvGrtGvfiavdillerikaealvdvfqtvkqlreqr RGSINIKQiQY . .|. || nlmvqtkd-qy |
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| Phosphatase | DDB_G0292024.AA | Subfamily.N_Nematode_4.PD | 75-140 | 30 | 3.8e-06 | 17.6 | In-house | 173-242 (264) | Show / Hide |
Range on Protein: 75-140 Range on HMM: 173-242/264 Sequence Identity: 30% (22 aa) DGGSPPDAVvnNWIKILGESYKKDSKETIGIHCVAGLGRAPVLVAIALIEG------GMNPLQAVEYIRERR | .| ||. ||.. ||.... | .|| ||.||. || | . . .. |. | .|. | dqvaPldaa--pviklykavkkkkkekPivvhcsaGvGrtatlvGidyatirirenseievldivrelramr |
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| Phosphatase | DDB_G0292024.AA | PTPc_motif | 64-159 | 18 | 4e-06 | 20.45 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 64-159 Range on HMM: 1-92/92 Sequence Identity: 18% (19 aa) IGIQVHDMPFADG-----GSPPDAVVNNWIKILGESYKKDSKETIGIHCVAGLGRAPVLVAIALIEGGMNPLQAVEYIRERRRGSINIKQIQYLKNYKSK . ..| . | | | .. .... . | | .|| || ||. ...|| .. .. .| |...|. |.|.. .. . TVHHYHYTNWPDHVEKDSGVPE----DSILEFIRHVRK-----PIVVHCSAGCGRTGTFCAIDMMMQQVDIFQTVKEMRKQRPGMVQTEEQYIFCYRCIL K . E |
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| Phosphatase | DDB_G0292024.AA | Subfamily.DSP19.PD | 39-155 | 24 | 4.2e-06 | 17.9 | In-house | 22-136 (139) | Show / Hide |
Range on Protein: 39-155 Range on HMM: 22-136/139 Sequence Identity: 24% (29 aa) ELKKYNVSHLVRAC--DPTYSTEPLQAIGIQVHDMPFADGGSppdaVVNNWIKILGESYKKDskETIGIHCVAGLGRAPVLV-AIALIEGGMNPLQAVEY .||| .. |.. |. .. .. |.. | | .. | . .. .. . |. .|| .. .|| || |.. .| | . ... .|.|..| ilkklkitHilnvavgvpnvfpkdftyksieilDlpetklls----ylkealdFieearskd--grvlvHCnAGvSRsasvviaylmkdeelslekalek IRERRR-GSINIKQIQYLKNY | |. . | |. ||.| vrearpcikPneGFikqLkey |
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| Phosphatase | DDB_G0292024.AA | Subfamily.R_Nematode_3.PD | 97-146 | 28 | 5.1e-06 | 17.2 | In-house | 195-251 (267) | Show / Hide |
Range on Protein: 97-146 Range on HMM: 195-251/267 Sequence Identity: 28% (16 aa) KDSKETIGIHCVAGLGRAPVLVAIAL-------IEGGMNPLQAVEYIRERRRGSINI . || .. .||..| .|. .|.|| | .| .. |. ....|. | | |. eksktpvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqt |
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| Phosphatase | DDB_G0292024.AA | Subfamily.N3.PD | 94-145 | 31 | 6.5e-06 | 16.7 | In-house | 187-244 (261) | Show / Hide |
Range on Protein: 94-145 Range on HMM: 187-244/261 Sequence Identity: 31% (18 aa) SYKKDSKETIGIHCVAGLGRAPVLVA----IALIEG--GMNPLQAVEYIRERRRGSIN .... ..| . .|| ||.||. ||.. .|||| ..||. | .|..| .. klrsgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvq |
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| Phosphatase | DDB_G0292024.AA | Subfamily.R_Nematode_2.PD | 96-148 | 25 | 1e-05 | 16.1 | In-house | 189-248 (261) | Show / Hide |
Range on Protein: 96-148 Range on HMM: 189-248/261 Sequence Identity: 25% (15 aa) KKDSKETIGIHCVAGLGRAPVLVAIALIEGGMNP------LQAVEYIRERRRGSINIK-Q |.|.. | .|| ||.||. ..... .. .. .|.. .|| | .| . | vkksekPivvhCsaGiGRtmafigteylareveadptieltealkelrehRwkgiqtesq |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| DDB_G0292024.AA | Protein | None | 166 | None | Fasta, JSON |
| DDB_G0292024.NA | RNA | None | 501 | None | Fasta, JSON |
| DDB_G0292024.AA.PD_13-159 | Protein Phosphatase Domain | None | 147 | None | Fasta, JSON |