DDB_G0278311
Species: D.discoideum
Alias: DDB_G0278311
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Myotubularin
Subfamily: MTM_unclassified
Protein domain

Protein domains of DDB_G0278311.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
DDB_G0278311.AA Myotub-related 521-660 42 1.3e-51 182.59 Pfam 1-121 (121) Show / Hide
Range on Protein: 521-660
Range on HMM: 1-121/121
Sequence Identity: 42% (59 aa)

YFICDSYPGLMGVPESITDEQLKSVAQFRSKGRIPVLSYRHWSNKCSITRCSQPMVGIGGNRSTEDENLLNSIRMTSTAGSGSSGGSGGSGSGSNKENNS
| ||..||..  || ||.|..|| ||.|||.||.|||..|| .|...|.|||||.||. |.|. ||| |...|. .. .                     
YEICPTYPAKLVVPKSISDDELKKVAKFRSWGRFPVLCWRHQENGAVICRCSQPLVGWWGWRCKEDEKLVQAIMKANAD-------------------MI

SDRTLYILDCRPYANAVGNRAKGAGWEILNNYPGCTLEFL
  | .||.| |||.||. ||||| | |.  .|| . . |.
QSRKMYIVDARPYTNAMANRAKGGGYENEEHYPNWEFVFM

Phosphatase DDB_G0278311.AA Subfamily.MTMR1.PD 674-822 53 2.8e-55 175.2 In-house 1-149 (149) Show / Hide
Range on Protein: 674-822
Range on HMM: 1-149/149
Sequence Identity: 53% (80 aa)

KIKDAAVSSIDkEDGWFNQLESSGWFGHIKLVIQGATRLAKLIHLQHHNVLVHCSDGWDRTSQLVSLAELLLDPYFRTIRGFQILIEKEWLSFGHKFAQR
|.|...  ||| |  |...||.. |. ||||...|| |.|. .. ..  |.||||||||||.|| ||| ||||.|.|||.||..||||||||||||||.|
klkeivypsid-eskwlsaleetkwlehiklilagavriadkvesektsvvvhcsdgwdrtaqltslamllldsyyrtikgfevliekewlsfghkfaer

CGQVHGK-DESEQSPILYQFIEACYQIIHQFPSKFEFNANFLKTILYHSY
 |  . .  ....||.. |||.. .|. .|||. |||| .|| ||| | |
ighgdknhadadrspvflqfidcvwqvtrqfptafefneeflitildhly

Phosphatase DDB_G0278311.AA Family.Myotubularin.PD 686-822 55 1.4e-63 201.9 In-house 4-141 (141) Show / Hide
Range on Protein: 686-822
Range on HMM: 4-141/141
Sequence Identity: 55% (77 aa)

EDGWFNQLESSGWFGHIKLVIQGATRLAKLIHLQHHNVLVHCSDGWDRTSQLVSLAELLLDPYFRTIRGFQILIEKEWLSFGHKFAQRCGQVHGK-DESE
|  |...|||. |. ||||....|..... .. ....||||||||||||.||.|||.||||||.|||.||..||||||||||||||.|.|. . . .|.|
ekkwlselestkWlehiklllkaavkivekvekektsvlvhcsdGWdrtaqltslaqllldpyyrtieGfevliekeWlsfGhkfaerlghgdkseseee

QSPILYQFIEACYQIIHQFPSKFEFNANFLKTILYHSY
.||...|||...||...|||..||||..|| .|| |.|
rsPvflqfidcvyqltkqfptafefnesflikildhly

Phosphatase DDB_G0278311.AA Subfamily.MTMR3.PD 689-822 45 1.1e-52 166.7 In-house 1-135 (135) Show / Hide
Range on Protein: 689-822
Range on HMM: 1-135/135
Sequence Identity: 45% (61 aa)

WFNQLESSGWFGHIKLVIQGATRLAKLIHLQHHNVLVHCSDGWDRTSQLVSLAELLLDPYFRTIRGFQILIEKEWLSFGHKFAQRCGQVHGKDE-SEQSP
....||.. |. |.  ... | .... .. .   ||||||||||||.|.|.||.||||||.||..||..|.|.|||.||||||.|||. ..|. .|..|.
flsalektkwlqhlsvllkaavkvvnavdkegrpvlvhcsdgwdrtpqivalakllldpyyrtlegfkvlverewldfghkfadrcghgedsddlnercp

ILYQFIEACYQIIHQFPSKFEFNANFLKTILYHSY
. |.... .|. .|||. ||||  ||  .. |.| 
vflqwldcvhqlkkqfptsfefneaflvklvqhty

Phosphatase DDB_G0278311.AA Subfamily.C2-MTMR1.PD 688-818 54 2.3e-52 165.8 In-house 5-133 (137) Show / Hide
Range on Protein: 688-818
Range on HMM: 5-133/137
Sequence Identity: 54% (69 aa)

GWFNQLESSGWFGHIKLVIQGATRLAKLIHLQHHNVLVHCSDGWDRTSQLVSLAELLLDPYFRTIRGFQILIEKEWLSFGHKFAQRCGqvHGKDESEQSP
|. ||||..|. .|| |...|. .|. ..      |||||||||||||||.||.||||||.||| |...|||||||.||||| .| |. .  ||.|||. 
qwlsqlestqwlayikavlkaaraiarkveklavsalvhcsdgwdrtsqlvllaqllldpyyrtidglivliekewlafghkfderlg--gadsvsersp

ILYQFIEACYQIIHQFPSKFEFNANFLKTIL
||..  ||.  |||| ||..|..|  .    
iflqfldclyqvtkqfpsafeytarlllkla

Phosphatase DDB_G0278311.AA Subfamily.R_Nematode_3.PD 685-761 24 2.4e-06 15.9 In-house 162-228 (267) Show / Hide
Range on Protein: 685-761
Range on HMM: 162-228/267
Sequence Identity: 24% (19 aa)

KEDGWFNQLESSGWFGHI-KLVIQGATRLAKLIHLQHHNVLVHCSDGWDRTSQLVSlaellldpyfrTIRGFQILIEK
|.   .. |  .||  .  .   . |. |.| ..    .|.||||||  |.  |..           .. |.| .|..
kkeftvthllykgWkelnapeepkealelikfveksktpvvVHCsdGisRsatlaa-----------ielgyqliiks

Sequence
Name Sequence Type Origin Length Description Download
DDB_G0278311.AA Protein None 1002 None Fasta, JSON
DDB_G0278311.NA RNA None 3009 None Fasta, JSON
DDB_G0278311.AA.PD_690-822 Protein Phosphatase Domain None 133 None Fasta, JSON