DG1060
Species: D.discoideum
Alias: DDB_G0281953, DG1060
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: OCA
Subfamily: OCA
Protein domain

Protein domains of DG1060.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase DG1060.AA Family.OCA.PD 4-164 55 4.4e-76 242.8 In-house 1-163 (165) Show / Hide
Range on Protein: 4-164
Range on HMM: 1-163/165
Sequence Identity: 55% (91 aa)

HIPPLNFGMVADDLYRSGQPNELNFPFLEKLQLKKIIFLAPDD-PSQQFQNFVEDQDIELIHLGMDTHQNPWNPISEEIVISALKIILNPDNYPLHIMCN
.||||||..|...||||..||||||.||..|.||.||.|.|.. |......|||...|.|||...|........|.||.....|||.|..||||..|.||
lipplnFstveeelyrssypnelnfsflktLkLktiislspeelpqesllkfveeeniklihikvdkkkkdlveieeellkrvlkilldvdnypvlihcn

LGRHRTGTVVGCLRKLQRWNLTSIFEEYRRFAGSKVKLLNEQFIELFDTDLVTY-NNAPQWLY
 |.||||.|||||||||.|||.||.||||||.|||...|.|.|||||||.|... |..|.||.
kGkhrtglvvgclRklqkWnlasileEyrrFsgskirileeefielfdteleveknkkpkwlk

Phosphatase DG1060.AA Subfamily.OCA.PD 4-164 55 4.4e-76 242.8 In-house 1-163 (165) Show / Hide
Range on Protein: 4-164
Range on HMM: 1-163/165
Sequence Identity: 55% (91 aa)

HIPPLNFGMVADDLYRSGQPNELNFPFLEKLQLKKIIFLAPDD-PSQQFQNFVEDQDIELIHLGMDTHQNPWNPISEEIVISALKIILNPDNYPLHIMCN
.||||||..|...||||..||||||.||..|.||.||.|.|.. |......|||...|.|||...|........|.||.....|||.|..||||..|.||
lipplnFstveeelyrssypnelnfsflktLkLktiislspeelpqesllkfveeeniklihikvdkkkkdlveieeellkrvlkilldvdnypvlihcn

LGRHRTGTVVGCLRKLQRWNLTSIFEEYRRFAGSKVKLLNEQFIELFDTDLVTY-NNAPQWLY
 |.||||.|||||||||.|||.||.||||||.|||...|.|.|||||||.|... |..|.||.
kGkhrtglvvgclRklqkWnlasileEyrrFsgskirileeefielfdteleveknkkpkwlk

Phosphatase DG1060.AA Y_phosphatase2 4-166 39 1.4e-66 227.93 Pfam 1-184 (184) Show / Hide
Range on Protein: 4-166
Range on HMM: 1-184/184
Sequence Identity: 39% (72 aa)

HIPPLNFGMVAD---DLYRSGQPNELNFPFLEK-LQLKKIIFLAPDDPSQQFQN--FVEDQDIELIHLGMDTHQNP-----------WNPISEEIVISAL
 .|||||..|.     .|||..|...|||||.  | || || | | ...|   .  | |   |...| .|.    |           | .| .. .. .|
VVPPLNFSHVEPTDVYIYRSSYPRPNNFPFLRHQLHLKTIIWLCPEPYPQDNLCEKFCESHHIKYYHIHMEGNKDPDNDCPKIKKNPWVNIPDHCMRRCL

KIILNPDNYPLHIMCNLGRHRTGTVVGCLR-KLQRWNLTSIFEEYRRFAGS-KVKLLNEQFIELFDTDLVTYNN--APQWLYLS
...||.||||. | || |.||||.|.|||| ||| ||..||..|||||... |   . |.||| |||...   .  .. |. . 
QTLLNKDNYPCYIHCNRGKHRTGCVIGCLRKKLQNWNTASICNEYRRFSHPRKRRIHDEEFIEMFDTNIEVHDHNKKWKWCWHC

Phosphatase DG1060.AA Family.DSP.PD 13-148 20 1.2e-10 29.9 In-house 110-239 (387) Show / Hide
Range on Protein: 13-148
Range on HMM: 110-239/387
Sequence Identity: 20% (28 aa)

VADDLYRSGQPNELNFPFLEKLQLKKIIFLApDDPSQqFQNfveDQDIELIHLGMDTHqNPWNPISeeIVISALKIILNP--DNYPLHIMCNLGRHRTGT
. . ||  .  .  |.. |..|. .||. |. ||..| |..   ...|. .....| | |.... .  ....|...| .   ..    . |. |.|.||.
ilphlylgsllaaknlewlkelgvtkivnlt-ddkpq-ftk---elgikylripidDh-napplen--lfekaidfieegndskgvVlVHCkaGkgRsgt

VVGCLRKLQ-RWNLTSIFEEYRRFAGsKVKLLNEQFIEL
. . .  . ...|   .. .|     .|   |..|..  
liiaYlmksegltleealdwvrskRp-gvitpnqgflkq

Phosphatase DG1060.AA Subfamily.DSP23.PD 76-144 26 5.1e-06 15.2 In-house 46-118 (128) Show / Hide
Range on Protein: 76-144
Range on HMM: 46-118/128
Sequence Identity: 26% (19 aa)

PISEEIVISALKIIL--NPDNYPLHIMCNLGRHRTGTVVGCL-RKLQRWNLTS-IFEEYRRFAGSKVKLLNEQ
| . | |   ..|.   .  . .. . | ||. ||||.. |   | ..      | |  .|  ||      |.
PPaleqvarlvriveeaekkeeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrrkGsietveqek

Sequence
Name Sequence Type Origin Length Description Download
DG1060.AA Protein None 166 None Fasta, JSON
DG1060.NA RNA None 501 None Fasta, JSON
DG1060.AA.PD_4-166 Protein Phosphatase Domain None 163 None Fasta, JSON