• Phosphatome.Net

Gene DDB_G0286143

DDB_G0286143
Species: D.discoideum
Alias: DDB_G0286143
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: HAD
Family: FCP
Subfamily: DULLARD
Protein domain

Protein domains of DDB_G0286143.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase DDB_G0286143.AA CPDc 170-314 38 3.4e-61 210.53 SMART 1-173 (173) Show / Hide 
Range on Protein: 170-314
Range on HMM: 1-173/173
Sequence Identity: 38% (67 aa)

TKKTLILDLDETLVHS--------------TLKPVTHHQITVK----------VLIEDMDCTFYVIKRPHVDYFLEKVSQWYDIVIFTASMQQYADPLLD
 ||||.||||.|||||              ..|. | ......          | |.. .. .|| |||||..||...|.||....||..|  ||||.||
KKKTLVLDLDHTLVHSCMIPTLHHWMKYLRSFKEWTRRDFIWPQLKWFHMCMIVEIDGHPHQWYVKKRPHVHEFLKRCSKWYEMHVFTMGMRMYADPVLD

QLD-TH-KVFKKRLFRDSCLEKDGN-FVKD-LSMIDQ-DLTSTIIIDNSPIAYSNNLENALPIDNWMGDNPSDT
 || .. ... .||.||.| ...|. .||| || .   || ..||||.|| ... . |||.||  | .. ..||
MLDPKRKYFIYRRLYRDHCVYHKGKTYVKDTLSLVNRCDLSMVIIIDDSPDSWPWHPENAIPIKPWFYF-MHDT
Phosphatase DDB_G0286143.AA NIF 172-333 41 6.1e-80 276.69 Pfam 1-189 (189) Show / Hide 
Range on Protein: 172-333
Range on HMM: 1-189/189
Sequence Identity: 41% (78 aa)

KTLILDLDETLVHST--LKPVTHHQITVKVLIEDMDCTFYVIK-RPHVDYFLEKVSQWYDIVIFTASMQQYADPLLDQLDT--HKVF--KKRL---FRDS
|||.|||||||||..   .|. .|...|.. ........||.| ||..|.||...|..|.|||.||||. ||||..|..|.  .|.|  ..||   .|..
KTLVLDLDETLVHCNPWWEPPNWHDFIVPIPFNGQNHQWYVYKPRPYCDEFLQHMSKYYEIVIWTASMKEYADPVIDYIDPKSKKYFDGHHRLICWYREH

CL-EKDG-NF-V-KDLSMI--DQ-DLTSTIIIDNSPIAYSNNLENALPIDN-WMG-----DNPSD--TSLLSLLPFL-EIIR-HV-QDVR
|  ...| |. | ||||..  .  || ..||.||||...  . .|..||.  |.|     |.|.|  . ||.||||| | ..  . .|||
CWLYRNGGNYYVKKDLSILWYNRWDLSRVIIVDNSPHSW-LQPDNGIPIPPYWYGYHDDDDSPDDFWNELLDLLPFLIEYLALQCLDDVR
Phosphatase DDB_G0286143.AA Subfamily.DULLARD.PD 171-333 52 2.4e-76 244.3 In-house 2-172 (172) Show / Hide 
Range on Protein: 171-333
Range on HMM: 2-172/172
Sequence Identity: 52% (90 aa)

KKTLILDLDETLVHS--------TLKPVTHHQITVKVLIEDMDCTFYVIKRPHVDYFLEKVSQWYDIVIFTASMQQYADPLLDQLDT-HKVFKKRLFRDS
.|||.|||||||.||        |.|..|......|||||.....|||.||||||.||..||.|||.|||||||..||....|.||. ....|.|..|..
rktlvldldetlihsahdsvtkstvkegtapdfklkvlierepvlfyvykrPhvdlfldvvskWydlviftasmeeyaaavvdkldsgrgilkrryyrqh

CLEKDGNFVKDLSMIDQDLTSTIIIDNSPIAYSNNLENALPIDNWMGDnPSDTSLLSLLPFLEIIRHVQDVR
|....|...||||....||.|.||.||||.||..|..||.||..|. | ||||.||.|||||...|...|||
CtlesgkytkdlslvsedlssviilDnspvayrknpdnaipikswisd-psdtallnllPfldalrftkdvr
Phosphatase DDB_G0286143.AA Family.FCP.PD 171-333 56 5.3e-63 201.0 In-house 2-164 (164) Show / Hide 
Range on Protein: 171-333
Range on HMM: 2-164/164
Sequence Identity: 56% (92 aa)

KKTLILDLDETLVHSTLKPVTHHQITVKVLIEDMDCTFYVIKRPHVDYFLEKVSQWYDIVIFTASMQQYADPLLDQLDT-HKVFKKRLFRDSCLEKDGNF
||.|.||||||||||.|||.......||| |.....|.|| ||||.|.||||||..|.|||||||...||||..| ||. .|.|||||.||.|  ..|| 
kklLVlDLdetLvhselkpknkpdfvvkveideleetvyvkkRPhldeFLekvselyeiviftastrkyadpvadiLDpekklfkkrllrdecvlvkgny

VKDLSMIDQDLTSTIIIDNSPIAYSNNLENALPIDNWMGDnPSDTSLLSLLPFLEIIRHVQDVR
|||||....||...||||.|| .|..| .||........| |.||.||.|||||| .....|||
vkdLsklgrdlskviiiDdspdsyklnpdnaikvksfked-pkDteLldLlpfleslakeedvr
Phosphatase DDB_G0286143.AA Subfamily.SCP.PD 171-333 50 3.9e-62 197.8 In-house 2-163 (163) Show / Hide 
Range on Protein: 171-333
Range on HMM: 2-163/163
Sequence Identity: 50% (82 aa)

KKTLILDLDETLVHSTLKPVTHHQITVKVLIEDMDCTFYVIKRPHVDYFLEKVSQWYDIVIFTASMQQYADPLLDQLDTHKVFKKRLFRDSCLEKDGNFV
||.|.||||||||||..|||.. ...| | |...    ||.|||.|| ||.||.. ...|.||||...||||..| ||...|.|.||||.||..||.|||
kkclvldldetlvhssfkpvenadfvvpveidgtvhqvyvlkrpfvdeflkkvgelfevvlftaslakyadpvadlldkknvikarlfrescvfhkgnyv

KDLSMIDQDLTSTIIIDNSPIAYSNNLENALPIDNWMgDNPSDTSLLSLLPFLEIIRHVQDVR
|| . .||....|.|||| .|  . .||.|.. |. |...|| || |||.|| ...|.||.  
kdlsrlGrdlkkvvivdnspasyifhpdnavpveswf-ddeedtelldllplleelskvedvl
Phosphatase DDB_G0286143.AA Subfamily.HSPC129.PD 171-333 46 6.9e-52 164.6 In-house 2-164 (164) Show / Hide 
Range on Protein: 171-333
Range on HMM: 2-164/164
Sequence Identity: 46% (77 aa)

KKTLILDLDETLVHSTLKPVTHHQITVKVLIEDMDCTFYVIKRPHVDYFLEKVSQWYDIVIFTASMQQYADPLLDQLDTH-KVFKKRLFRDSCLEKDGNF
. .|.|||||||||..|... . ... ||  .|.  . ||  ||.. .|||.||. .....|||| . ||| ||| || . | ...||||. |.  |||.
efslvldldetlvhcslakledatlsfkveyqdktyqvyvrlrpflreflervsklfevilftaskkvyadklldlldpekklvrhrlfrehcvcvdgny

VKDLSMIDQDLTSTIIIDNSPIAYSNNLENALPIDNWMGDNpSDTSLLSLLPFLEIIRHVQDVR
.||||.. .||. |||.|||| |.. .||| .||. |. |.  |. || |||||| . . .|||
ikdlsilGrdlsktiivdnspqafayqlenGipieswfade-ndsellkllpfleklaekedvr
Phosphatase DDB_G0286143.AA Group.HAD.PD 171-333 35 4.9e-46 146.4 In-house 1-190 (190) Show / Hide 
Range on Protein: 171-333
Range on HMM: 1-190/190
Sequence Identity: 35% (67 aa)

KKTLILDLDETLV-HSTLKPVTHHQITVKVLIEDMD----CTFYVIKR------------PHVDYFLEKVSQWYDIVIFTASMQQYADPLLDQLDT-HKV
|.||.||||..|. |.. .| . .   .||||...       .|..||            ||.|.|||.|...|..|.|||.. .||||... .|...|.
kdtlvlDldgvlwlhgspepleglrskgkvlifltnnatksrlyllkrlallgflveevephldeflervgelyelvvftagtreyadpvvgavdvgdea

FKKRLFRDSCLEKDGNFVK------DLSMIDQDLTSTIIIDNSPIAYSN--NLENALPIDNWMgDNPSDTSLLSLLPFLEII--RHVQDVR
.|..||.| . .|....      ||... .||....||||.| ..    | ||||.| ... |...|. || |.|.||.|  |...||.  
fsyrklrdacvylkgpgalllatnrdlgalvrdlekvviidnkpsvfafecnpenalmigdfi-ddildaellglipdlenidvrfgkdvg
Phosphatase DDB_G0286143.AA Subfamily.TIM50.PD 173-333 36 8.9e-34 105.8 In-house 4-150 (150) Show / Hide 
Range on Protein: 173-333
Range on HMM: 4-150/150
Sequence Identity: 36% (59 aa)

TLILDLDETLVHSTLKpvthhqitvkvliedMDCTFYVIKRPHVDYFLEKVSQWYDIVIFTASMQQYADPLLDQLDTHKVFKKRLFRDSCLEKDGNFVKD
||.|.|...|||.  .               ..  . . ||| ||.|||.... ..||.||..   .| ||.|.|| ... . |||||...||. |||||
tlvlelkdvlvhpewt---------------yktGwrfkkrPgvdafleelaelfeivvftseqgltaaplidkldPkqlimyrlfrdatkyvdGehvkd

LSMIDQDLTSTIIIDNSPIAYSNNLENALPIDNWMGDNpSDTSLLSLLPFLEIIR--HVQDVR
....||.  |..|  . ..  . |||| ...| |..  |..|| ||.||..|   .|.|||  
lsklnrdlskvivvdldkesvklqpenalalkkwkGna-ddrelldllaflktiatsevedvr
Phosphatase DDB_G0286143.AA Subfamily.FCP1.PD 171-299 30 4.9e-20 61.5 In-house 2-136 (150) Show / Hide 
Range on Protein: 171-299
Range on HMM: 2-136/150
Sequence Identity: 30% (41 aa)

KKTLILDLDETLVHSTLKPVTHHQI-----TVKVLIEDMDCTFYVIKRPHVDYFLEKVSQWYDIVIFTASMQQYADPLLDQLDT-HKVFKKR-LFRDSCL
| .|..|||.||.|.| .|  . .        |  .   ....|| .||..  ||||.|. |.. |.| . ..||. .   ||  .|.|..|| || .|.
klvLvvDlDqtlihttkdptievkeeklkdikkftlpeekevyyvklRpnlkeFleklsklyelhiytmgtraYaeqiakilDpekklFserilsrdell

EKDGNFVKDLSMIDQDLTSTIIIDNSPIAYsNNLEN
.  .. |  ......    .|||.    . |. || 
nassktkklkklfptgdsmvviiDDredvW-nfaen
Sequence
Name Sequence Type Origin Length Description Download
DDB_G0286143.AA Protein None 344 None Fasta, JSON
DDB_G0286143.NA RNA None 1035 None Fasta, JSON
DDB_G0286143.AA.PD_170-333 Protein Phosphatase Domain None 164 None Fasta, JSON