• Phosphatome.Net

Gene DDB_G0270196

DDB_G0270196
Species: D.discoideum
Alias: DDB_G0270196
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: HAD
Family: FCP
Subfamily: FCP_unclassified
Protein domain

Protein domains of DDB_G0270196.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase DDB_G0270196.AA CPDc 194-320 20 3.6e-09 20.08 SMART 1-173 (173) Show / Hide 
Range on Protein: 194-320
Range on HMM: 1-173/173
Sequence Identity: 20% (36 aa)

KKYTLVIDIDALTEIT------------KTSKYPTLYK-----------------------------RAGLDFFLDHLRKDYEIYLYFNGNIPQNKYEQL
||.|||.|.|     .            . |...  ..                             | ... ||... | ||....  |. .  .  ..
KKKTLVLDLDHTLVHSCMIPTLHHWMKYLRSFKEWTRRDFIWPQLKWFHMCMIVEIDGHPHQWYVKKRPHVHEFLKRCSKWYEMHVFTMGMRMYAD--PV

QFKIDTNGKYFTGL-LYPETGIKERNQ-FSKK-IEMLDR-DPSKVIFID--AASPYDHP-NVINIGKFKSNSKDK
  ..| ..|||    || .    .. . . |.    . | |.|.||.||   .|  .|| | | | .......|.
LDMLDPKRKYFIYRRLYRDHCVYHKGKTYVKDTLSLVNRCDLSMVIIIDDSPDSWPWHPENAIPIKPWFYFMHDT
Phosphatase DDB_G0270196.AA Family.FCP.PD 198-341 28 4e-25 77.8 In-house 5-164 (164) Show / Hide 
Range on Protein: 198-341
Range on HMM: 5-164/164
Sequence Identity: 28% (47 aa)

LVIDIDA-----------------LTEITKTSKYPTLYKRAGLDFFLDHLRKDYEIYLyFNGNIPQNKYEQLQFkIDTNGKYFTGLLYPETGIKERNQFS
||.|.|                    ||.....  . .|| .|| ||... ..|||.. |. .  .   . ... .|...|.|.  |. .. . .... .
LVlDLdetLvhselkpknkpdfvvkveideleetvyvkkRPhldeFLekvselyeivi-ftastrkyadpvadi-LDpekklfkkrllrdecvlvkgnyv

KKIEMLDRDPSKVIFID---AASPYDHPNVINIGKFKSNSKDKLLIELLPVLESFSrKNlDDVR
|....|.|| ||||.||   ..  . . |.|.. .||...||. |..|||.|||.. |. .|||
kdLsklgrdlskviiiDdspdsyklnpdnaikvksfkedpkDteLldLlpflesla-ke-edvr
Phosphatase DDB_G0270196.AA NIF 196-341 23 3e-24 89.95 Pfam 1-189 (189) Show / Hide 
Range on Protein: 196-341
Range on HMM: 1-189/189
Sequence Identity: 23% (46 aa)

YTLVIDIDALTEITKTS---KYP------------------TLYK-RAGLDFFLDHLRKDYEIYLYFNGNIPQNKYEQLQFKIDTN-GKYF--TGLL---
.|||.|.|    .  ..   ..|                   .|| | ..| ||.|..|.|||...  ..  ..  ...  .||.. .|||  .. |   
KTLVLDLDET--LVHCNPWWEPPNWHDFIVPIPFNGQNHQWYVYKPRPYCDEFLQHMSKYYEIVIWTASM--KEYADPVIDYIDPKSKKYFDGHHRLICW

YP-ETG-IKERNQF-S-KKIEML--DR-DPSKVIFIDAASP--YDHPNVINIGK-FKS-----N-SKD--KLLIELLPVLESFSR-KNLDDVR
|  ..  .......   | . .|  .| | |.||..| ..   .   | | |   ...     .  .|  . |..||| |. ... . |||||
YREHCWLYRNGGNYYVKKDLSILWYNRWDLSRVIIVDNSPHSWLQPDNGIPIPPYWYGYHDDDDSPDDFWNELLDLLPFLIEYLALQCLDDVR
Phosphatase DDB_G0270196.AA Subfamily.TIM50.PD 195-341 26 2.7e-17 52.4 In-house 2-150 (150) Show / Hide 
Range on Protein: 195-341
Range on HMM: 2-150/150
Sequence Identity: 26% (41 aa)

KYTLVIDIDAL---TEITKTSKYPTlYKRAGLDFFLDHLRKDYEIYLYFNGNIPQnkYEQLQFKIDTNGKYFTGLLYPETGIKErNQFSKKIEMLDRDPS
.||||.... .   .| |. . . .  || |.|.||..| . .|| .. . .. .    .|  |.| ..     |. . |  ..  .  |...|.|| ||
pytlvlelkdvlvhpewtyktGwrf-kkrPgvdafleelaelfeivvftseqglt--aaplidkldPkqlimyrlfrdatkyvd-Gehvkdlsklnrdls

KVIFIDAA---SPYDHPNVINIGKFKSNSKDKLLIELLPVLESFSRKNLDDVR
|| .|        .. |.... |.| |..|. |..||..|.  . .. .||| 
kvivvdldkesvklqpenalalkkwkGnaddrelldllaflktiatsevedvr
Phosphatase DDB_G0270196.AA Subfamily.DULLARD.PD 212-333 25 9.5e-16 47.0 In-house 44-166 (172) Show / Hide 
Range on Protein: 212-333
Range on HMM: 44-166/172
Sequence Identity: 25% (30 aa)

SKYPTLYKRAGLDFFLDHLRKDYEIYLYFNGNipQNKYEQLQFKIDTNGKYFTGLLYPETGIKERNQFSKKIEMLDRDPSKVIFIDAASP-Y--DHPNVI
.|||  .|.||| . | |.. ..  .   ..  ...  |.|.. . ..  .| .  ..| ....|.. ... | |.|| .| ..|     | |.|  . |
pvlfyvykrPhvdlfldvvskWydlviftasm--eeyaaavvdkldsgrgilkrryyrqhCtlesgkytkdlslvsedlssviilDnspvayrknpdnai

NIGKFKSNSKDKLLIELLPVLESFS
...|. |..|||.|...        
pikswisdpsdtallnllPfldalr
Phosphatase DDB_G0270196.AA Subfamily.SCP.PD 208-336 23 3.7e-11 32.1 In-house 32-160 (163) Show / Hide 
Range on Protein: 208-336
Range on HMM: 32-160/163
Sequence Identity: 23% (30 aa)

ITKTSKYPTLYKRAGLDFFLDHLRKDYEIYLYFNGnipQNKYE-QLQFKIDTNgKYFTGLLYPETGIKERNQFSKKIEMLDRDPSKVIFIDAAS---PYD
| .| .     ||  .| ||... . .|. |.      ..||  ..   .|.. . ..  |. |. .  .... |..  | || .||. .| ...  | .
idgtvhqvyvlkrpfvdeflkkvgelfevvlftas---lakyadpvadlldkk-nvikarlfrescvfhkgnyvkdlsrlGrdlkkvvivdnspasyifh

HPNVINIGKFKSNSKDKLLIELLPVLESFSRKN
 .  . ....|. | .|||.||..|...     
pdnavpveswfddeedtelldllplleelskve
Phosphatase DDB_G0270196.AA Subfamily.HSPC129.PD 221-341 28 5.5e-11 31.6 In-house 45-164 (164) Show / Hide 
Range on Protein: 221-341
Range on HMM: 45-164/164
Sequence Identity: 28% (34 aa)

AGLDFFLDHLRKDYEIYLYFNGNipQNKYEQLQFKIDTNGKYFTGLLYPETGIKERNQFSKKIEMLDRDPSKVIFIDAA---SPYDHPNVINIGKFKSNS
|  ||... | .|. |.   .  .   ..|   .| . |..   |. |  .   ... |....| || || | .| .     |.  || |  . ....|.
pflreflervsklfevilftask--kvyadklldlldpekklvrhrlfrehcvcvdgnyikdlsilGrdlsktiivdnspqafayqlenGipieswfade

KDKLLIELLPVLESFSRKnlDDVR
 |..|||.||.. .|  .|||   
ndsellkllpfleklaek--edvr
Phosphatase DDB_G0270196.AA Group.HAD.PD 209-340 21 1.4e-09 27.5 In-house 37-189 (190) Show / Hide 
Range on Protein: 209-340
Range on HMM: 37-189/190
Sequence Identity: 21% (33 aa)

TKTSKYPTLYKR------------AGLDFFLDHLRKDYEIYLYFNGNIPQnkYEQLQFKIDT-NGKYFTGLLYPETGIKERnQFSK------KIEMLDRD
. |. .  |.||             .|| ||... ..||. .. .|.      ...  ..|  .. .   .|  .. .     . .         .|||.
natksrlyllkrlallgflveevephldeflervgelyelvvftagtrey--adpvvgavdvgdeafsyrklrdacvylkg-pgalllatnrdlgalvrd

PSKVIFID-AASPY----DHPNVINIGKFKSNSKDKLLIELLPVLESFSRKNLDDV
.||. ||  .| .    . .|.. ||.|.....|. |. |.| ||. . .. .|| 
lekvviidnkpsvfafecnpenalmigdfiddildaellglipdlenidvrfgkdv
Phosphatase DDB_G0270196.AA Subfamily.FCP1.PD 208-313 21 2.1e-06 17.3 In-house 37-143 (150) Show / Hide 
Range on Protein: 208-313
Range on HMM: 37-143/150
Sequence Identity: 21% (23 aa)

ITKTSKYPTLYKRAGLDFFLDHLRKDYEIYLYFNGNipQNKYEQLQFKIDTNGKYFT-GLLYPETGIKERNQFSKKIEMLDRDPSKVIFIDAASP--YDH
......  .  .| .|  ||..| | ||...|  |.  ..  ||.   .| ..| |.  .|  .  ... ....|  ...... | |. ||.     ..|
lpeekevyyvklRpnlkeFleklsklyelhiytmgt--raYaeqiakilDpekklFserilsrdellnassktkklkklfptgdsmvviiDDredvWnfa

PNVINIGKF
.|.. ..  
enlikvkpy
Sequence
Name Sequence Type Origin Length Description Download
DDB_G0270196.AA Protein None 374 None Fasta, JSON
DDB_G0270196.NA RNA None 1125 None Fasta, JSON
DDB_G0270196.AA.PD_194-341 Protein Phosphatase Domain None 148 None Fasta, JSON