DDB_G0271690
Species: D.discoideum
Alias: DDB_G0271690
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: HAD
Family: FCP
Subfamily: FCP1
Protein domain

Protein domains of DDB_G0271690.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase DDB_G0271690.AA Subfamily.FCP1.PD 134-285 45 9.2e-61 193.5 In-house 1-149 (150) Show / Hide
Range on Protein: 134-285
Range on HMM: 1-149/150
Sequence Identity: 45% (71 aa)

KKLSLVLDLDHTVIHAVTEQGFnSSPEwrnkdKNKNGIHTITV-NGPMNYCIKKRPHLVKFLTEVNKIYELHIYTMGTRNYANEIAKLIDPESSIFKERI
.|| ||.|||.|.||..... . ...|     .....|...|. . ...|..|.||.| .||....|.|||||||||||.||..|||..|||...|.|||
rklvLvvDlDqtlihttkdpti-evke-----eklkdikkftlpeekevyyvklRpnlkeFleklsklyelhiytmgtraYaeqiakilDpekklFseri

LSRDD--GNGINFKSLQRLFPCDDSMVLIVDDRSDVWKKSKNLIQISPYVYFTDV
||||.   .  ..|.|..|||..||||.|.|||.|||....|||...||..|..|
lsrdellnassktkklkklfptgdsmvviiDDredvWnfaenlikvkpykfFkgv

Phosphatase DDB_G0271690.AA CPDc 134-286 33 1.1e-48 169.0 SMART 1-173 (173) Show / Hide
Range on Protein: 134-286
Range on HMM: 1-173/173
Sequence Identity: 33% (58 aa)

KKLSLVLDLDHTVIHA-------VTEQGFNSSPEWRNK----DKNKNGIH----TITVNGPMNYCIKKRPHLVKFLTEVNKIYELHIYTMGTRNYANEIA
||..|||||||| .|.         . . .| .||...      .|.. |    .   . |. . .|||||.  ||....| ||.|..|||.|.|| ...
KKKTLVLDLDHTLVHSCMIPTLHHWMKYLRSFKEWTRRDFIWPQLKWF-HMCMIVEIDGHPHQWYVKKRPHVHEFLKRCSKWYEMHVFTMGMRMYADPVL

KLIDPESSIFKERILSRDDGNGINFKS----LQRLFPC-DDSMVLIVDDRSDVWKKSK-NLIQISPYVYFTDVV
...||.   |  |.|.||.    . |.    . .|... |.|||.|.||..|.|.. . |.|.|.|. || .  
DMLDPKRKYFIYRRLYRDHCVYHKGKTYVKDTLSLVNRCDLSMVIIIDDSPDSWPWHPENAIPIKPWFYFMHDT

Phosphatase DDB_G0271690.AA Family.FCP.PD 134-280 35 1e-40 128.3 In-house 1-139 (164) Show / Hide
Range on Protein: 134-280
Range on HMM: 1-139/164
Sequence Identity: 35% (53 aa)

KKLSLVLDLDHTVIHAvteqgfnsspEWRNKdKNKNGIHTITVNG-PMNYCIKKRPHLVKFLTEVNKIYELHIYTMGTRNYANEIAKLIDPESSIFKERI
||. ||||||.|..|           |...| .... ........ ......|||||| .||..|...||..|.|..||.||...|...|||...||.|.
kkklLVlDLdetLvhs----------elkpk-nkpdfvvkveideleetvyvkkRPhldeFLekvselyeiviftastrkyadpvadiLDpekklfkkrl

LsRDD---GNGINFKSLQRLfPCDDSMVLIVDDRSDVWKKSK-NLIQISPYV
| ||.    .| . |.|..| ..|.|.|.|.||..|..|  . |.|..... 
l-rdecvlvkgnyvkdLskl-grdlskviiiDdspdsyklnpdnaikvksfk

Phosphatase DDB_G0271690.AA NIF 136-282 27 2.4e-29 108.39 Pfam 1-153 (189) Show / Hide
Range on Protein: 136-282
Range on HMM: 1-153/189
Sequence Identity: 27% (47 aa)

LSLVLDLDHTVIHAVTEQGFNSSPEWRNKDKNKNGIHTITV-----NGPMNYCIKK-RPHLVKFLTEVNKIYELHIYTMGTRNYANEIAKLIDPE-SSIF
. ||||||.| .|..        |.|. ..      | ..|     ...... ..| ||..  || ...|.||..|.|.....||... . |||.   .|
KTLVLDLDETLVHCN--------PWWEPPN-----WHDFIVPIPFNGQNHQWYVYKPRPYCDEFLQHMSKYYEIVIWTASMKEYADPVIDYIDPKSKKYF

-KERIL---SRD----DGNG----INFKSLQRLFPCD-D-SMVLIVDDRSDVWKK-SKNLIQISPYVYF
 . ..|   .|.      ||    . .| | .|...  | | |.|||.....|     |.|.|.|| ..
DGHHRLICWYREHCWLYRNGGNYYV-KKDLSILWYNRWDLSRVIIVDNSPHSW-LQPDNGIPIPPY-WY

Phosphatase DDB_G0271690.AA Group.HAD.PD 136-286 22 7.3e-23 70.6 In-house 2-167 (190) Show / Hide
Range on Protein: 136-286
Range on HMM: 2-167/190
Sequence Identity: 22% (39 aa)

LSLVLDLDHTVIhavTEQGFNSSPEWRNKDKNKNGIHTitVNGPMNYCIKKR------------PHLVKFLTEVNKIYELHIYTMGTRNYANEIAKLIDP
.||||||....    . ...    .| |.|.. .. .     .... ..||            ||| .||. | ..|||...|.|||.||......|.. 
dtlvlDldgvlw---lhgspepleglrskgkvlifltn--natksrlyllkrlallgflveevephldeflervgelyelvvftagtreyadpvvgavdv

ESSIFKERILSRDDG----NGINFKSL--QRLFPCDDSM-VLIVDDRSDVWK---KSKNLIQISPYvyFTDVV
 .|. |.| ..      .| ..      . ... | . | |.|....|..   . .| . | ..  ..|.   
gdeafsyrklrdacvylkgpgalllatnrdlgalvrdlekvviidnkpsvfafecnpenalmigdf--iddil

Phosphatase DDB_G0271690.AA Subfamily.DULLARD.PD 135-288 27 2.5e-21 65.0 In-house 2-153 (172) Show / Hide
Range on Protein: 135-288
Range on HMM: 2-153/172
Sequence Identity: 27% (42 aa)

KLSLVLDLDHTVIHAVTEQGFNSspEWRNKDKNKNGIHTITVNGPMNYCIKKRPHLVKFLTEVNKIYELHIYTMGTRNYANEIAKLIDPESSIFKERILS
.  ||||||.|.||. ...  .|  . ... ...  .. .. . |... . ||||.  ||. | | |.| |.| ....||....  .|. .|.|.|    
rktlvldldetlihsahdsvtks--tvkegtapdfklkvlierepvlfyvykrPhvdlfldvvskWydlviftasmeeyaaavvdkldsgrgilkrryyr

RDD--GNGINFKSLQRLFPcDDSMVLIVDDRSDVWK-KSKNLIQISPYvyFTDVVDS
.    .|   |.|  . . | | |.|.|. .  .. . .| |.|. .  ..|  |  
qhCtlesgkytkdlslvse-dlssviilDnspvayrknpdnaipiksw--isdpsdt

Phosphatase DDB_G0271690.AA Subfamily.HSPC129.PD 135-267 25 2.5e-14 42.3 In-house 2-125 (164) Show / Hide
Range on Protein: 135-267
Range on HMM: 2-125/164
Sequence Identity: 25% (34 aa)

KLSLVLDLDHTVIHAVTEQGFNSSPEWRNKDKNKngIhtitvngpMNYCIKKRPHLVKFLTEVNKIYELHIYTMGTRNYANEIAKLIDPESSIFKERILs
. ||||||| |..|.  ..  ... ... . ..|  .        ..  .. ||.| .||  | |..|. ..|  .. ||... .|.|||   .. |.  
efslvldldetlvhcslakledatlsfkveyqdk--t--------yqvyvrlrpflreflervsklfevilftaskkvyadklldlldpekklvrhrlf-

RDDGNGIN---FKSLQrLFPCDDSMVLIVDDRSDVW
|.    ..    | |. ..  | |  .|||. .  .
rehcvcvdgnyikdls-ilGrdlsktiivdnspqaf

Phosphatase DDB_G0271690.AA Subfamily.SCP.PD 135-299 26 1.4e-13 39.8 In-house 2-155 (163) Show / Hide
Range on Protein: 135-299
Range on HMM: 2-155/163
Sequence Identity: 26% (44 aa)

KLSLVLDLDHTVIHAVTEQgfnsspeWrnkdKNKNGIHTITVNGPM-NYCIKKRPHLVKFLTEVNKIYELHIYTMGTRNYANEIAKLIDPESsIFKERIL
| .|||||| |..|. ...            .| . . .. ..| . .  ..|||.. .||..| ...|. ..|    .||...|.|.|.....| |.  
kkclvldldetlvhssfkp-------v----enadfvvpveidgtvhqvyvlkrpfvdeflkkvgelfevvlftaslakyadpvadlldkkn-vikarlf

sRDD---GNGINFKSLQRLFpCDDSMVLIVDDRSDVWK-KSKNLIQISpyVYFTDVVDSLHHEKQPLLQQ
|.     .|   | | ||   | . |.|||.    .  ...| . ..   .| |  |.  ..  |||.. 
-rescvfhkgnyvkdlsrlG-rdlkkvvivdnspasyifhpdnavpve--swfddeedtelldllpllee

BRCT DDB_G0271690.AA BRCT 430-509 19 4.4e-12 47.17 Pfam 1-84 (84) Show / Hide
Range on Protein: 430-509
Range on HMM: 1-84/84
Sequence Identity: 19% (17 aa)

VKKDILKGTYIVFSGVYPLGTPIQKQPLRWLAEEFGSVVQNDINNETTHVI--AQRK---GTSK-VNKALSKGLKVISPQWLIEST
.  ...||  ... | ..  .  . . .. ..|..|  |..... .|||||  ...    .|.| ..||.........|.|.... 
H-EKPFKGCTFCITGGFDNMNRDEIH-WQEMIEKHGGKVTDSVSKQTTHVIPWVGEPHCTRTKKFYWKAKEWNIPIVHPDWIWDCI

Phosphatase DDB_G0271690.AA Subfamily.TIM50.PD 181-279 26 4.1e-10 28.8 In-house 23-122 (150) Show / Hide
Range on Protein: 181-279
Range on HMM: 23-122/150
Sequence Identity: 26% (27 aa)

NYCIKKRPHLVKFLTEVNKIYELHIYTMGTRNYANEIAKLIDPESSIFKEriLSRDD---GNGINFKSLQRLFpCDDSMVLIVDDR-SDVWKKSKNLIQI
.  |||| . .|| |. . .|. ..|  .  .| ..   .||.. |  .  | ||     .| . | |. |   | | |..||   . |.. .| .....
GwrfkkrPgvdafleelaelfeivvftseqgltaaplidkldPkqlimyr--lfrdatkyvdGehvkdlskln-rdlskvivvdldkesvklqpenalal

SPY
.  
kkw

BRCT DDB_G0271690.AA BRCT 432-512 19 2.1e-09 38.49 SMART 1-93 (93) Show / Hide
Range on Protein: 432-512
Range on HMM: 1-93/93
Sequence Identity: 19% (19 aa)

KDILKGTYIVFSGVYPL---GTPIQKQPLRWLAEEFGSVVQND-----INNETTHVIAQRKGTSKVN----------KALSKGLKVISPQWLIESTRIW
 ...||  ....| ..     .   .. |....|..|  |  .     . ..|||||. . ...|.           ||.. |.....|.|.... . |
MKPFKGCTFCITG-DDIEGNFD-M-RDELKEMIEMHGGKVT-SVSRKRC-PDTTHVIC-SPENPKYETWNRMMTKYMKAIAWGIWIVHPDWIWDCIKKW

Sequence
Name Sequence Type Origin Length Description Download
DDB_G0271690.AA Protein None 782 None Fasta, JSON
DDB_G0271690.NA RNA None 2349 None Fasta, JSON
DDB_G0271690.AA.PD_134-286 Protein Phosphatase Domain None 153 None Fasta, JSON