DDB_G0288707
Species: D.discoideum
Alias: DDB_G0288707
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: HAD
Family: FCP
Subfamily: FCP1
Protein domain

Protein domains of DDB_G0288707.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase DDB_G0288707.AA Subfamily.FCP1.PD 573-736 37 1.8e-55 176.3 In-house 1-149 (150) Show / Hide
Range on Protein: 573-736
Range on HMM: 1-149/150
Sequence Identity: 37% (61 aa)

PKMYLIVDIDHTLLHSTKDPNAESYYLKDNSINKFTITETNETFYVKQRPNAIEFLSSLSSQFKIYLYSFHPKYYVEQLALILDPNRSIFT-KVITKEvi
.|..|.||.|.||.|.||||..|... |...|.|||..|..|..|||.|||..|||..||.......|......|.||.| ||||....|.......   
rklvLvvDlDqtlihttkdptievkeeklkdikkftlpeekevyyvklRpnlkeFleklsklyelhiytmgtraYaeqiakilDpekklFserilsrd--

epvEPLPPINSIGKPYIVFNNQNfskifnfeaiNQMIILDDREDVWrNFQDNLILLDTFKFFNTN
  |.|.......|....|....          ....|.||||||| ||..||| ....|||... 
---ellnassktkklkklfptgd----------smvviiDDredvW-nfaenlikvkpykfFkgv

Phosphatase DDB_G0288707.AA Family.FCP.PD 574-731 28 5e-33 103.3 In-house 2-139 (164) Show / Hide
Range on Protein: 574-731
Range on HMM: 2-139/164
Sequence Identity: 28% (45 aa)

KMYLIVDIDHTLLHSTKDPNAESYYLKdnsinKFTITETNETFYVKQRPNAIEFLSSLSSQFKIYLYSFHPKYYVEQLALILDPNRSIFTKVITKEVIEP
|..|..|.|.||.||...|.... . .     |..|.|..||.|||.||.. |||...|....|...... . |....| ||||....|.| .....  |
kklLVlDLdetLvhselkpknkpdfvv-----kveideleetvyvkkRPhldeFLekvselyeiviftastrkyadpvadiLDpekklfkkrllrdecvl

VEPlPPINsigkpyivfnnqNFSKIfnFEAINQMIILDDREDVWRNFQDNLILLDTFK
.    ..            . ||.   .  ...||.||..|......||.| ...|| 
vkg-nyvk------------dLskl--grdlskviiiDdspdsyklnpdnaikvksfk

Phosphatase DDB_G0288707.AA CPDc 573-737 19 1.4e-16 62.32 SMART 1-173 (173) Show / Hide
Range on Protein: 573-737
Range on HMM: 1-173/173
Sequence Identity: 19% (37 aa)

PKMYLIVDIDHTLLHSTKDPNA--ESYYLK---DNSINKFTIT-ETNE-------------TFYVKQRPNAIEFLSSLSSQFKIYLYSFHPKYYVEQLAL
.|  |..|.||||.||...|.   . .||.   ... ..|..  ....              .||| || . |||. .|  . .....   . |..... 
KKKTLVLDLDHTLVHSCMIPTLHHWMKYLRSFKEWTRRDFIWPQLKWFHMCMIVEIDGHPHQWYVKKRPHVHEFLKRCSKWYEMHVFTMGMRMYADPVLD

ILDPNR-SIFTKVITKEVIEPVEPL----PPINSIGKPYIVFNNQNFSKIFN-FEAINQMIILDDREDVWRNFQDNLILLDTFKFFNTNS
.|||.|  .........    ...     .                  ...| ..  .  ||.||..|.|. . .|.|    ...|  . 
MLDPKRKYFIYRRLYRDHCVYHKGKTYVKD----------------TLSLVNRCDL-SMVIIIDDSPDSWPWHPENAIPIKPWFYFMHDT

Phosphatase DDB_G0288707.AA Group.HAD.PD 576-734 12 5e-15 45.1 In-house 3-165 (190) Show / Hide
Range on Protein: 576-734
Range on HMM: 3-165/190
Sequence Identity: 12% (23 aa)

YLIVDIDHTLL-HSTKDPNAESYYLKDNSINKFTiTETNETFYVKQR------------PNAIEFLSSLSSQFKIYLYSFHPKYYVEQLALILDPNRSIF
|..|.|..|  |.. .|..   ... . |. .. . |.  .|...|            |.. ||| ...  ... .... .. |..... ..|. ..| .
tlvlDldgvlwlhgspepleglrskgkvlifltn-natksrlyllkrlallgflveevephldeflervgelyelvvftagtreyadpvvgavdvgdeaf

TKVITKEVIEPVEPlPPIN---------SIGKPYIvfnnqnfskifnfeainQMIILDDREDVWRN--FQDNLILLDTFkFFN
 . ...   .   |  .          ... .                  . .|.|.. .|.    . .| ...  | ...  
syrklrdacvylkg-pgalllatnrdlgalvrdle-----------------kvviidnkpsvfafecnpenalmigdf-idd

Phosphatase DDB_G0288707.AA Subfamily.DULLARD.PD 575-730 20 4.4e-12 34.9 In-house 3-146 (172) Show / Hide
Range on Protein: 575-730
Range on HMM: 3-146/172
Sequence Identity: 20% (33 aa)

MYLIVDIDHTLLHSTKDPNAESYYLK---DNSINKFTITETNETFYVKQRPNAIEFLSSLSSQFKIYLYSFHPKYYVEQLALILDPNRSIFTKVITKEVI
|..|.|.||.||..|  ..|   .    . . | .|.... .||| .||   .||. .|  . . ..    . | ....  || .|.|...   ..    
ktlvldldetlihsahdsvtkstvkegtapdfklkvlierepvlfyvykrPhvdlfldvvskWydlviftasmeeyaaavvdkldsgrgilkrryyrqhC

EPVeplppinsigkpyI--------VFnnqnfskifnFEAINQMIILDDREDVWRNFQDNLILLDTF
                       .            | ....||||.    .|.. || | ....  
tle-------------sgkytkdlslv----------sedlssviilDnspvayrknpdnaipiksw

Phosphatase DDB_G0288707.AA NIF 575-731 18 8.1e-12 44.97 Pfam 1-153 (189) Show / Hide
Range on Protein: 575-731
Range on HMM: 1-153/189
Sequence Identity: 18% (33 aa)

MYLIVDIDHTLLHSTKDPNAESYYLKDNSINKFTITETNETFYVKQ-RPNAIEFLSSLSSQFKIYLYSFHPKYYVEQLALILDPN-RSIF--TKVI---T
  |. |.|.||.|..   ... .....  | ...... | ..||.  || . ||| ..|  . |....   | |....  ..||. . .|  ....   .
KTLVLDLDETLVHCN---PWWEPPNWHDFIVPIPFNGQNHQWYVYKPRPYCDEFLQHMSKYYEIVIWTASMKEYADPVIDYIDPKSKKYFDGHHRLICWY

KE---VIEPVEPLPPINSIGKPYIVFNNQ-NF-S-KIFNFEAI-------NQMIILDDREDVWRNFQDNLILLDT-FK
 |   .                   . |. |.   |  .   .       ...||.|.. ..|   .||.|. .. ..
REHCWL-------------------YRNGGNYYVKK--DLSILWYNRWDLSRVIIVDNSPHSW-LQPDNGIPIPPYWY

Phosphatase DDB_G0288707.AA Subfamily.HSPC129.PD 573-665 26 2.4e-11 32.6 In-house 1-88 (164) Show / Hide
Range on Protein: 573-665
Range on HMM: 1-88/164
Sequence Identity: 26% (24 aa)

PKMYLIVDIDHTLLHSTKDPNAESyylkdnsINKFTITETN--ETFYVKQRPNAIEFLSSLSSQFKIYLYSFHPKYYVEQLALILDPNRSIFTKV
|.. |..|.| ||.|..  .  ..         .|...  .   . ||. || . |||. .| .|.. |..   | | ..|  .|||... .   
pefslvldldetlvhcslakleda-------tlsfkveyqdktyqvyvrlrpflreflervsklfevilftaskkvyadklldlldpekklvrhr

Phosphatase DDB_G0288707.AA Subfamily.SCP.PD 574-666 27 9.8e-11 30.5 In-house 2-89 (163) Show / Hide
Range on Protein: 574-666
Range on HMM: 2-89/163
Sequence Identity: 27% (25 aa)

KMYLIVDIDHTLLHSTKDPNAESYYlkdnsINKFTITETNETFYVKQRPNAIEFLSSLSSQFKIYLYSFHPKYYVEQLALILDPNRSIFTKVI
|. |..|.| ||.||.  |  .. .     .    | .|.   ||..||   |||. ..  |.. |..   . | ...| .||... | ... 
kkclvldldetlvhssfkpvenadf-----vvpveidgtvhqvyvlkrpfvdeflkkvgelfevvlftaslakyadpvadlldkknvikarlf

BRCT DDB_G0288707.AA BRCT 880-964 17 4.4e-10 40.74 SMART 1-93 (93) Show / Hide
Range on Protein: 880-964
Range on HMM: 1-93/93
Sequence Identity: 17% (17 aa)

SSVLMDCNIVFSGIFPKQIDPSKLCHTRVSKITESFGAKISLEIDS----TTTHLIFIKEGTSKAQQ---------ALKNPNIKVVHFAWLRDCVHRW
. .. .| ....|  ..  ...      . .. |..|.|.. ....    .|||.|  .....|  .         . .  .|..||. |. ||. .|
MKPFKGCTFCITG-DDIEGNFD-M-RDELKEMIEMHGGKVT-SVSRKRCPDTTHVIC-SPENPKYETWNRMMTKYMKAIAWGIWIVHPDWIWDCIKKW

BRCT DDB_G0288707.AA BRCT 910-961 28 8.8e-10 38.8 Pfam 28-84 (84) Show / Hide
Range on Protein: 910-961
Range on HMM: 28-84/84
Sequence Identity: 28% (16 aa)

KITESFGAKISLEIDSTTTHLI--FIKE--GTSKA-QQALKNPNIKVVHFAWLRDCV
.. |..|.|.. .....|||.|    ..   ..|    . |..||..||. |. ||.
EMIEKHGGKVTDSVSKQTTHVIPWVGEPHCTRTKKFYWKAKEWNIPIVHPDWIWDCI

Sequence
Name Sequence Type Origin Length Description Download
DDB_G0288707.AA Protein None 985 None Fasta, JSON
DDB_G0288707.NA RNA None 2958 None Fasta, JSON
DDB_G0288707.AA.PD_573-737 Protein Phosphatase Domain None 165 None Fasta, JSON