• Phosphatome.Net

Gene ctdspl2

ctdspl2
Species: D.discoideum
Alias: DDB_G0290365, ctdspl2
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: HAD
Family: FCP
Subfamily: SCP
Protein domain

Protein domains of ctdspl2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase ctdspl2.AA Subfamily.HSPC129.PD 389-551 60 1.7e-77 248.0 In-house 1-164 (164) Show / Hide 
Range on Protein: 389-551
Range on HMM: 1-164/164
Sequence Identity: 60% (100 aa)

PKISLVLDLDETLVHCSTEPLEQPHLTFPVFFNNTEYQVFAKKRPFFEEFLHKVSDIFEVIIFTASQEVYANKLLNMIDPN-NKIKYRLYRDSCVYVDGN
|. |||||||||||||| ..||.  |.|.| .....|||. . |||..|||..||..||||.||||..|||.|||...||. .....||.|. || ||||
pefslvldldetlvhcslakledatlsfkveyqdktyqvyvrlrpflreflervsklfevilftaskkvyadklldlldpekklvrhrlfrehcvcvdgn

YLKDLSVLGRDLKQVVIIDNSPQSFGFQVDNGIPIESWFEDENDKELLQLVPFLESLTNVEDVR
|.||||.|||||.. .|.|||||.|..|..|||||||||.||||.|||.|.||||.|.. ||||
yikdlsilGrdlsktiivdnspqafayqlenGipieswfadendsellkllpfleklaekedvr
Phosphatase ctdspl2.AA Subfamily.SCP.PD 390-551 56 2.8e-79 253.6 In-house 2-163 (163) Show / Hide 
Range on Protein: 390-551
Range on HMM: 2-163/163
Sequence Identity: 56% (92 aa)

KISLVLDLDETLVHCSTEPLEQPHLTFPVFFNNTEYQVFAKKRPFFEEFLHKVSDIFEVIIFTASQEVYANKLLNMIDPNNKIKYRLYRDSCVYVDGNYL
|..|||||||||||.|..|.|......||....|..||...||||..|||.||...|||..||||.. ||.......|..|.||.||.|.|||...|||.
kkclvldldetlvhssfkpvenadfvvpveidgtvhqvyvlkrpfvdeflkkvgelfevvlftaslakyadpvadlldkknvikarlfrescvfhkgnyv

KDLSVLGRDLKQVVIIDNSPQSFGFQVDNGIPIESWFEDENDKELLQLVPFLESLTNVEDVR
|||| ||||||.|||.||||.|. |..||..|.||||.||.|.|||.|.|.||.|..||||.
kdlsrlGrdlkkvvivdnspasyifhpdnavpveswfddeedtelldllplleelskvedvl
Phosphatase ctdspl2.AA NIF 391-551 42 6.7e-79 273.22 Pfam 1-189 (189) Show / Hide 
Range on Protein: 391-551
Range on HMM: 1-189/189
Sequence Identity: 42% (81 aa)

ISLVLDLDETLVHCS--TEPLEQPHLTFPVFFNNTEYQVFAKK-RPFFEEFLHKVSDIFEVIIFTASQEVYANKLLNMIDP--NNKI--KYRL---YRDS
. ||||||||||||.  .|| ...  ..|. ||.  .|.. .| ||. .||| ..| ..|..|.|||...||......|||  .. .  ..||   ||..
KTLVLDLDETLVHCNPWWEPPNWHDFIVPIPFNGQNHQWYVYKPRPYCDEFLQHMSKYYEIVIWTASMKEYADPVIDYIDPKSKKYFDGHHRLICWYREH

CV-YVDG-NY-L-KDLSVL--GR-DLKQVVIIDNSPQSFGFQVDNGIPIES-WFE-----D-END--KELLQLVPFL-ESLT-NV-EDVR
|. |..| ||   ||||.|  .| ||..|.|.||||.|. .| ||||||.. |..     | ..|  .|||.| ||| |.|  .. .|||
CWLYRNGGNYYVKKDLSILWYNRWDLSRVIIVDNSPHSW-LQPDNGIPIPPYWYGYHDDDDSPDDFWNELLDLLPFLIEYLALQCLDDVR
Phosphatase ctdspl2.AA CPDc 389-532 36 2.5e-66 227.59 SMART 1-173 (173) Show / Hide 
Range on Protein: 389-532
Range on HMM: 1-173/173
Sequence Identity: 36% (64 aa)

PKISLVLDLDETLVHC--------------STEPLEQPHLTFP----------VFFNNTEYQVFAKKRPFFEEFLHKVSDIFEVIIFTASQEVYANKLLN
.| .||||||.||||.              | ..  ..  ..|          | ......|.. ||||. .||| ..|  .|...||.....|| ..|.
KKKTLVLDLDHTLVHSCMIPTLHHWMKYLRSFKEWTRRDFIWPQLKWFHMCMIVEIDGHPHQWYVKKRPHVHEFLKRCSKWYEMHVFTMGMRMYADPVLD

MIDPNN-KIKYR-LYRDSCVYVDGN-YLKD-LSVLGR-DLKQVVIIDNSPQSFGFQVDNGIPIESWFEDENDK
|.||.. .. || ||||.|||..|. | || ||...| ||. |.|||.||.|. .. .|.|||..|| . .|.
MLDPKRKYFIYRRLYRDHCVYHKGKTYVKDTLSLVNRCDLSMVIIIDDSPDSWPWHPENAIPIKPWFYFMHDT
Phosphatase ctdspl2.AA Family.FCP.PD 390-551 52 5.3e-63 201.0 In-house 2-164 (164) Show / Hide 
Range on Protein: 390-551
Range on HMM: 2-164/164
Sequence Identity: 52% (85 aa)

KISLVLDLDETLVHCSTEPLEQPHLTFPVFFNNTEYQVFAKKRPFFEEFLHKVSDIFEVIIFTASQEVYANKLLNMIDP-NNKIKYRLYRDSCVYVDGNY
|. |||||||||||....| ..|.....| ....| .|. ||||...|||.|||...|..|||||.. ||.......|| .. .|.||.||.||.|.|||
kklLVlDLdetLvhselkpknkpdfvvkveideleetvyvkkRPhldeFLekvselyeiviftastrkyadpvadiLDpekklfkkrllrdecvlvkgny

LKDLSVLGRDLKQVVIIDNSPQSFGFQVDNGIPIESWFEDENDKELLQLVPFLESLTNVEDVR
 ||||.|||||..|.|||.||.|. .. ||.|...|..||..|.|||.|.|||||| ..||||
vkdLsklgrdlskviiiDdspdsyklnpdnaikvksfkedpkDteLldLlpfleslakeedvr
Phosphatase ctdspl2.AA Subfamily.DULLARD.PD 392-551 39 8.3e-50 157.9 In-house 4-172 (172) Show / Hide 
Range on Protein: 392-551
Range on HMM: 4-172/172
Sequence Identity: 39% (66 aa)

SLVLDLDETLVHC--------STEPLEQPHLTFPVFFNNTEYQVFAKKRPFFEEFLHKVSDIFEVIIFTASQEVYANKLLNMIDPNN-KIKYRLYRDSCV
|||||||||.|         ....  .|.... |  .... ...  |||. ..||..||  ....||||| |.||.......| ...| |.||..|.  .
tlvldldetlihsahdsvtkstvkegtapdfklkvlierepvlfyvykrPhvdlfldvvskWydlviftasmeeyaaavvdkldsgrgilkrryyrqhCt

YVDGNYLKDLSVLGRDLKQVVIIDNSPQSFGFQVDNGIPIESWFEDENDKELLQLVPFLESLTNVEDVR
|.| ||||..  ||..|.|.||||...  ..||.|||.||. | .|..||.|.|||..|  ..|||   
lesgkytkdlslvsedlssviilDnspvayrknpdnaipikswisdpsdtallnllPfldalrftkdvr
Phosphatase ctdspl2.AA Group.HAD.PD 392-548 34 1.3e-42 135.2 In-house 3-187 (190) Show / Hide 
Range on Protein: 392-548
Range on HMM: 3-187/190
Sequence Identity: 34% (63 aa)

SLVLDLDETLV-HCSTEPLEQPHLTFPVFFNN----TEYQVFAKKR------------PFFEEFLHKVSDIFEVIIFTASQEVYANKLLNMIDP-NNKIK
.||||||..|. |.| ||||.     .| ...    |. ... .||            |. .|||..|. ..|...|||... ||. .....|. ....|
tlvlDldgvlwlhgspepleglrskgkvlifltnnatksrlyllkrlallgflveevephldeflervgelyelvvftagtreyadpvvgavdvgdeafs

YRLYRDSCVYVDGNYLK------DLSVLGRDLKQVVIIDNSPQSFGF--QVDNGIPIESWFEDENDKELLQLVPFLESL--TNVE
|..||.|||..|.. .      ||..|.|||..||||||.|..|.|  . .|...|.....| .|.|||.|.|.||..   ... 
yrklrdacvylkgpgalllatnrdlgalvrdlekvviidnkpsvfafecnpenalmigdfiddildaellglipdlenidvrfgk
Phosphatase ctdspl2.AA Subfamily.TIM50.PD 422-551 39 1.4e-39 124.7 In-house 21-150 (150) Show / Hide 
Range on Protein: 422-551
Range on HMM: 21-150/150
Sequence Identity: 39% (52 aa)

NTEYQvfAKKRPFFEEFLHKVSDIFEVIIFTASQEVYANKLLNMIDPNNKIKYRLYRDSCVYVDGNYLKDLSVLGRDLKQVVIIDNSPQSFGFQVDNGIP
.| ..   ||||. . ||..... ||...||..| ..| .|.. .||.. |.|||.||.. ||||. .|||| | |||..|...|  ..|..| .| . .
ktGwr--fkkrPgvdafleelaelfeivvftseqgltaaplidkldPkqlimyrlfrdatkyvdGehvkdlsklnrdlskvivvdldkesvklqpenala

IESWFEDENDKELLQLVPFLESLT--NVEDVR
. |  ...|.|||.|..||. ..  .||||| 
lkkwkGnaddrelldllaflktiatsevedvr
Phosphatase ctdspl2.AA Subfamily.FCP1.PD 390-515 29 2e-21 66.1 In-house 2-134 (150) Show / Hide 
Range on Protein: 390-515
Range on HMM: 2-134/150
Sequence Identity: 29% (39 aa)

KISLVLDLDETLVHCSTEPL-EQPHLTFP---VF-FNNTEYQVFAKKRPFFEEFLHKVSDIFEVIIFTASQEVYANKLLNMIDPNNKIKY-R-LYRDSCV
|. ||.|||.||.|....|  | .. .      | .....   . |.||  .|||.|.|...|. |.| ..  ||... ...||..|.   || || .. 
klvLvvDlDqtlihttkdptievkeeklkdikkftlpeekevyyvklRpnlkeFleklsklyelhiytmgtraYaeqiakilDpekklFserilsrdell

YVDGNYLKDLSVLGRDLKQVVIIDNSPQSFGFQ
   .  |  ... .. ..|||||.  . . |. 
nassktkklkklfptgdsmvviiDDredvWnfa
Phosphatase ctdspl2.AA Subfamily.UBLCP1.PD 424-550 25 5e-06 15.3 In-house 20-164 (165) Show / Hide 
Range on Protein: 424-550
Range on HMM: 20-164/165
Sequence Identity: 25% (35 aa)

EYQVFAKKRPFFEEFLHKVSDIFEVIIFTASQEVYANKL----LNMIDPNNKIKYRLYRDSCVYVDG-NY----LKDLSVLGRDLKQ-----VVIIDNSP
...  |||..|||| .  . ... |..|..  . .        . .|| || . | .  .. |.  .|     | | |. . ||.. .|.  . |     
aedalelkrpyleefltsayedydiviwsatsmkwievklkelGvadnpnykiafvldstamikvttpkygvievkplgviwkklkkfsskntimfddlr

QSFGFQVDNGIPIESW----FEDENDKELLQLVPFLESLTNVEDV
||. |. .    .. ..|||||.|  .| .... ||.        
rnflmnpknGlkirpfkeadlnrdkdkellkltkylkeiakledf
Sequence
Name Sequence Type Origin Length Description Download
ctdspl2.AA Protein None 567 None Fasta, JSON
ctdspl2.NA RNA None 1704 None Fasta, JSON
ctdspl2.AA.PD_389-551 Protein Phosphatase Domain None 163 None Fasta, JSON