Gene spnA
spnA
Species: D.discoideum
Alias: DDB_G0276155, spnA
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of spnA.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| G-alpha | spnA.AA | G_alpha | 55-455 | 20 | 4.3e-14 | -49.68 | SMART | 1-400 (400) | Show / Hide |
Range on Protein: 55-455
Range on HMM: 1-400/400
Sequence Identity: 20% (94 aa)
AQQQKQNEQNLAQLSTSTSSNSSVNNTTNTNTNTTNSSSISSNNNNNNNTAVPILKAHDFCGT-----IMILGHTESGKTTLQRQLEFIYGV-TDPTDAK
... |. . | . ... ... . . .|| ||||.| |. |.. . . |
KRRNKEIDKQLEKDKKKKKKHGQ---------------------------------------SGREVKLLLLGAGESGKSTILKQMRIIHQNGFSQEERK
HYQRLIYGNTLATLIRFIENSERLNITLSPDNL-------ARVKRIQS---QPVELARN---RLPRFPLKLGWDCKCIWEDKVIQSVYNHSKI-----C-
.|. .|| |.. . |. |.|||...... .....| . .. ... . . ||. .. ..| .| |..||..|. .. .
EYRPIIYQNIIQSMRVLIDAMEHLNIPFEDPERENCNENEHHADYIMEYKNYMHDMWEEGCMDEEPFPPEYANAIKALWNDPGIQECYERRNEFQLHDST
---SEIRTPGRPKYYMDRMFKVFDPSYTPTEMDIISAYDQKDTIQSSAIIHKRFKV-------DLFGCSGKQSSPKNWVGLHQN-YKPNYIFYVVALKDY
|| ||..| ..|| | |||.||. .. || .. |... .| . | | | | . | . |...||| .|
IYISE-----YAKYFLDNIDRICDPDYVPTEQDILHCRVPTTGIQETCFEMKNHNFMGVHLQFRMFDVGGQRSERKKWIHCFDNSV--TAIIFCVALSEY
----FSDHLVATQNTDPTIVEMCNNHIHRNLLLESLNSFETLTKSELFDKSLAIYLIFNTSDIFYENIKQY---DLKSCFSEYEGG----------NDPE
| | . .| . |||| |.. | .| . .. | .| |.| | ||. ... ||..|.|. || |
DQCLFEDNTT------------------QNRMHESLNLFDSICNSRWFANMTSMILFLNKIDLFEEKIKHVPSNPIHDCFPDYKGPPTPPQDCHCDNDYE
KAVSFISNKFTKFLQ--------NKDKPYKSHIVN-LLDKNNVREEFEGIFDS-LKIDAEKRGF
.|. .| .|| . |..|.. .|. . | ||.. | |. .. .. |.
EACKYIKWKFRRLNRNRHQRHEQNSKKRIYCHFTCIATDTNNIQFVFDAVKDMIIQNNLKDCGL
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| Phosphatase | spnA.AA | PP2Cc | 694-970 | 24 | 2e-85 | 291.02 | SMART | 1-338 (338) | Show / Hide |
Range on Protein: 694-970
Range on HMM: 1-338/338
Sequence Identity: 24% (92 aa)
NGGVGSKIKLESGF--GSLQGRRKNMEDTHVILNNLMGAVTYNGPPKDIPISYYAVYDGHGGTETSTLLEPTVHNCLVNSQSFRDG--------------
. .|..... .|. | ||.|..||| ||. . ...|.|||||.|.. . | .|... .| ..
HS-MGYNSGWRYGYMESSMQGWRHPMEDAHVCRP------------------FFGVFDGHGGHECAQYCRKHLHEHLAEELQFHKDDDYKENDEMQDEPE
------------DYEQAFRDAYAEADDIVIEKCEKSGSTGVSALLVGNKLYTANVGDSEIVLARAQPNANPKGPV-TYEPVLLSYKHLASDDQEKKRVTD
| | |.|.|. ..|. .| | ||..|||||.|||||| .|| |.. . |..| . .|... |.. | ... |..|. .
MWWRMWHDKWFEDWEDALRKAFLRMDEEI--------CTAVVALIRGNKLYVANVGDSRAVLCRNGND-NWWG-IRHYTAHQLTEDHKPDNEDERRRIEQ
LGG--------MIIFN-----RLFGS---LAVSRSFGDKEYK--------------------EGEKKFCVSDPYQTTTDL------TARDHFFILACDGL
.|| .... |..|. |||||.|||..|| .... . ...|. |...| | | |.||.||||
AGGRVMPMHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKWKEDEKIEWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQMTVPTPDDDFLILCCDGL
WDKVEYDEAVQFVQRNI-----------------------KLGKSATEISELLAQDSYDRGSGDNITVLVV
||.....|.|..|.... | ... |....|.. . ||.||.||
WDVMSNQEVVDIVRKCLRKWHHKPVKNQAQENAHMMRHRQKKHNDPMEAAKRLCDCAI----CDNMTVIVV
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| G-alpha | spnA.AA | G-alpha | 376-436 | 33 | 8e-06 | 20.55 | Pfam | 270-340 (360) | Show / Hide |
Range on Protein: 376-436 Range on HMM: 270-340/360 Sequence Identity: 33% (24 aa) DIFYENIKQYD--LKSCFSEYE----GG-NDPEKAVSFISNKFTKFLQNKD---KPYKSHIVNLLDKNNVR |.| | || . .. || .|. |. .| | |. || || ||.. |. .|. |.||.| DLFEEKIKHTPSHISDCFPDYKDYQQGPPQDYEWACNFIKQKFWSLNQNNEKPDKEIYHHFTCATDTNNIR |
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| Phosphatase | spnA.AA | PP2C | 703-965 | 31 | 1.4e-99 | 341.92 | Pfam | 1-284 (284) | Show / Hide |
Range on Protein: 703-965 Range on HMM: 1-284/284 Sequence Identity: 31% (92 aa) LESGFGSLQGRRKNMEDTHVILNNLMGAVTYNGPPKDIPISYYAVYDGHGGTETSTLLEPTVH----NCLVNSQSFRDG---DYEQAFRDAYAE-ADDIV ...||...||.|. |||.|....|.. . .......||.|||||..... . ..| ..| . .||..| |.|||.|....| . |.. WDYGFCRMQGWRHFMEDAHHCYPNMNCS-----SSGKDSWHFFAVFDGHGGHQAAKYCRKHLHKAMNTILKERKSFPEGNPKDVEQALRKSFLECDTDMM IEK------------CEKSGSTGVSALLVGNK--LYTANVGDSEIVLARAQPNANPKGPVTYEPVLLSYKHLASDDQEKKRVTDLGGMII---FNRLFGS . . |..||.| |.|.....| ||.||.||| .||.|.. .|. ...|.|.| .|...|..|....||... |.|..|. FYSAPWHEQNVMHWECWHSGCTAVCAYIRNQKNILYVANCGDSRAVLCRNGNAHNW-------VHQLTYDHKPSNEDERRRIRQAGGWVMWWGFWRVNGV -LAVSRSFGDKEYKEGE-----KKFCVSDPYQT-TTDLTAR-DHFFILACDGLWDKVEYDEAVQFVQRNIKLGKSATEISELLAQDSYDRGSGDNI |||||.|||..|| .. .. ....|. | ....| |.|.|||||||||.....|....|..... .....|..| |.......|| ||| WLAVSRAFGDFHYKPNHTCFPKEQPVTAEPDITPEHKITPDHDEFLILACDGLWDVMSDQEVCDIVRQCRSDWNDPMEACEKLVDYCIAYGSEDNI |
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| Phosphatase | spnA.AA | Subfamily.ILKAP.PD | 699-970 | 38 | 4.1e-98 | 318.3 | In-house | 5-298 (298) | Show / Hide |
Range on Protein: 699-970 Range on HMM: 5-298/298 Sequence Identity: 38% (114 aa) SKIKLESGFGSLQGRRKNMEDTHVILNNLMGAvTYNGPPKDIPISYYAVYDGHGGTETSTLLEPTVHNCLV-----NSQSFRDGDYEQAFRDAYAEADDI ||.|||..|....|.|..|||.|||||.|. . |... .| ...|||||.|||.|...|.... ..|...| ...|..| .......||....|. skyklegafaerkGereemeDahvilndldeq-trkekskvsrvsyyavfDGhaGsrasefaaeklhkviveklpkedvsakdkeikkclvdafkktDee VIEKCE------KSGSTGVSALLVGNKLYTANVGDSEIVLARAQPNANPKGPVTYEPVLLSYKHLASDDQEKKRVTDLGGMIIFNRLFGSLAVSRSFGDK ...... |.|||.|..|.|.|.||.||.|||..|||||..... .|..|...||||..| .....|.||... ||.....|..|.|.||||.||. flklaskakPvWkdGstavvvlvvdnvlyvanlGDskavlaRakeegdkagestiasvlLskdHtpasyeerkriqkaGgvvrdgRvlGvlevsRsiGDg EYKEGEkkfCVSDPYQTTTDLTARDHFFILACDGLWDKVEYDEAVQFV----------QRNIKLGKSATEI-----SELLAQDSYDRGSGDNITVLVV ..|| . ..|.|......||..|.|..|||||||...|.||.|.|. ... . ||||.|..| ||.....|||.||.|||.| rfkelg---vistPdvkkceLtenDlfvvlaCDGLwkvfeadevvkfilkvlededdrkikqeegksaeevrfevacerlAseavkrgssDnvtvllv |
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| Phosphatase | spnA.AA | Group.PPM.PD | 699-973 | 34 | 1.7e-70 | 227.8 | In-house | 34-322 (459) | Show / Hide |
Range on Protein: 699-973
Range on HMM: 34-322/459
Sequence Identity: 34% (99 aa)
SKIKLESGFGSLQGRRKNMEDTHVILNNLMGAVtyngppkdipiSYYAVYDGHGGTETSTLLEPTVHNCLVNSQSFRD------------------GDYE
|. .| |. | ||.||.|||.||| .|. |...|.|||||.| . . . . ...| .. .. .....|.|.|. | |. |...
sgnglrygvasmqgwrkemEDrhvivenfdnnd-----------sffgVfDGHgGaeaaefaakkLpkilkkqlkkkkdevskksaeasldnddrgekvk
QAFRDAYAEADDIVIEKCEK-------SGSTGVSALLVGNKLYTANVGDSEIVLARAQpnanpkgpvtyEPVLLSYKHLASDDQEKKRVTDLGGMIIF-N
. ||.| |.||. |.|||.||.||| .|| |.. ..| ||. | ....|..|....||. .|. |.|||||..|| ..|.
kalrsafleldedlseeanekeepgkdsGtTAvvalingkklyvANaGDSravLcrng-----------kavplskdHkpenpeEreRIekagGsveidg
RLFGSLAVSRSFGDKEYKEgEKKFCVSDPYQTTTDLTARDHFFILACDGLWDKVEYDEAVQFVQRNIKL-----GKSATEISELLAQDSYDRGSG-----
|. . ..|. .. .|| |.|..||.||||| .. .|.|.||..... .|...||.| |... ..|| |||||.|| ||
RvnGilavsRalGdhdlkk-eeqmvsaePdvsvvklteedeflvlAsDGlWdvlsneevvefvretlekkkkelkkdleeiaerlvdealakgstgdgts
-DNITVLVVILN
cDNiTvivvtln
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| Phosphatase | spnA.AA | Family.PPM.PD | 699-973 | 33 | 8.7e-68 | 218.8 | In-house | 11-287 (495) | Show / Hide |
Range on Protein: 699-973 Range on HMM: 11-287/495 Sequence Identity: 33% (98 aa) SKIKLESGFGSLQGRRKNMEDTHVILNNLMGAVtyngppkdiPISYYAVYDGHGGTETSTLLEPTVHNCLVNSQSFRD------------GDYEQAFRDA |. .|. |. | ||.|..|||.||...|| . . ..|...|.|||||.| . . . . |..| ..... | ....|.|.| ssnglrygvasmqgwrsemeDahvvvenlenne---------dfslfgvfDGhgGaeaaefaakklhkilkkqlekkddeksstsaessaekvkealrka YAEADDIVIEKCE------KSGSTGVSALLVGNKLYTANVGDSEIVLARAQpnanpkgpvtyEPVLLSYKHLASDDQEKKRVTDLGGMIIF--NRLFGSL . | | . |... .||.| |..|. |.|||.||.|||..|| |.. ..| ||..| ....|..|....|| ..|. |.||||| fleldeelseelneksagkdsGtTAvvvlirgkklyvAnaGDsravLcrng-----------kavelskdHkpenpeEreRIekagGkvvirdgrvnGvl AVSRSFGDKEYKEGEKKFCVSDPYQTTTDLT-ARDHFFILACDGLWDKVEYDEAVQFVQRNI-KLGKSATEISELLAQDSYDRGSGDNITVLVVILN ..|| ..|. |. . ...|. |...|| |.|..||.||||| .. .|.|..|.... . .....||.| | . . .||.|||||||| |. avsRalGdfdlkkeeqaivsaePditsvkltqeedeflvlasdGlWdvlsneevvelvretleekeedleeiaeeLvdealakgsrDNiTvlvvaly |
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| Phosphatase | spnA.AA | Subfamily.PPM1A.PD | 700-972 | 31 | 3.1e-57 | 184.1 | In-house | 7-278 (309) | Show / Hide |
Range on Protein: 700-972 Range on HMM: 7-278/309 Sequence Identity: 31% (90 aa) KIKLESGFGSLQGRRKNMEDTHVILNNLMGAVtyngppKDipISYYAVYDGHGGTETSTLLEPTVHNCLVNSQSFR-------DGDYEQAFRDAYAEADD . .| | | || | .|||.|.. .| ... || |..||.|||.|.. |. . .... ......|. ....|.|... |.|. gnglryglssmqgwRvemEDahtavidlpskl------kd--wsffavfDGHaGskvskycakhlleaileeeefkaskeksskekvkealrkgfLelDe IVI-----EKC-EKSGSTGVSALLVGNKLYTANVGDSEIVLARAQpnanpkgpvtyEPVLLSYKHLASDDQEKKRVTDLGGMIIFNRLFGSLAVSRSFGD . .|. .||||| |..|. .|||.||.||| .||.|.. . | .. | .||..||.|... ||... .|. |||||||..|| kirklvelskgedksGsTavvvlvspkklylancGDsRavlsrng-----------kvvfateDHkpsdpkEkeRienAgGsvmikRvnGsLAvsRalGD KEYKEG-----EKKFCVSDPYQTTTDLTARDHFFILACDGLWDKVEYDEAVQFVQRNIKLGKSATEISELLAQDSYDRGSGDNITVLVVIL ..||| ... ...|. |... .. |.|..|||||.|| .. .|...||........ ..|... | .. .|| ||..|..|.| ydykekpekkateqlvspepevtvierdeedeflvlacDGiwDvmsneevaefvksrlevtddleevanelldtcLekgsrDNmsvilvll |
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| Phosphatase | spnA.AA | Subfamily.PPM1E.PD | 709-972 | 32 | 2.2e-54 | 174.4 | In-house | 17-269 (269) | Show / Hide |
Range on Protein: 709-972 Range on HMM: 17-269/269 Sequence Identity: 32% (86 aa) SLQGRRKNMEDTHVILNNLMGAVTYngpPKDIPISYYAVYDGHGGTETSTLLEPTVHNCLVNSQSFRDgDYEQAFRDAYAEADDIVIEK----CEKSGST .....|. ||| ||.|..| . .. .....||.|||||.|... .|. ||. ... . | ..|...|. ..|. ...|. |||||.|.. avknkrrkmEDrhvaledlnelfel---kdekeraffavfDGHgGveaakyaaahlhellvrqeklke-dpaealkeafkltDerflqkaereklksGst GVSALLVGNKLYTANVGDSEIVLARAQpnanpkgpvtyEPVLLSYKHLASDDQEKKRVTDLGGMIIF---NRLFGSLAVSRSFGDKEYkegeKKFCVSDP |. ...|| | .|||. .| | . | | | | ....||||. ..||.... | |.|.|||.||... |.. .... ... avvvliekdqlyvaWlGDsqallvrkg-----------eavqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRaiGDvkl----kpyvsgea YQTTTDLTARDHFFILACDGLWDKVEYDEAVQFVQRNIKLGK-SATEISELLAQDSYDRGSGDNITVLVVIL .|. ... ||||||||| |. .|.|. |. .. |. . .|...|| . ....|| |||||.||.| dvaeveldgsedylilacDGlwDvvneeevvklveefladgaedlsevakllveaakeagssDnitvvvvfl |
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| Phosphatase | spnA.AA | Subfamily.PPM1G2.PD | 700-970 | 31 | 1.6e-50 | 161.7 | In-house | 7-275 (275) | Show / Hide |
Range on Protein: 700-970 Range on HMM: 7-275/275 Sequence Identity: 31% (90 aa) KIKLESGFGSLQGRRKNMEDTHVILNNLMGAvtyngpPKDIPISYYAVYDGHGGTETSTLLEPTVHNCLVNSQSFRDGDYEQAFRDAYAEADDIVIEK-- . ... | .|.|| | ||||.|.. |.|. . | ....||.|||||.. . ... ... .||..| ||...||. || .... nariavgvssmqGyrlnmeDahilenellek------sddkslalfavfDGhGGakvakyagkklikkiakkksfkegaleqilkdafletDeellkdek --CEKSGSTGVSALLVGNKLYTANVGDSEIVLARAQPnANPkgpvtyepvlLSYKHLASDDQEKKRVTDLGGMIIFNRLFGSLAVSRSFGDKEYKEGE-- |..||| |..|. .||| ||.||| ||. . .. ||. | .. .||||... ||.. .|||.||.||..|| |.|... lkdesaGstavvvlikeeklyvanaGDsravlsskgn-vka----------lsfDhkPqeesekkriiaagGfvelnrvngnLalsralgDfefkknvkk ---KKFCVSDPYQTTTDLTARDHFFILACDGLWDKVEYDEAVQFVQRNIKLGKSATEISELLAQDSYDRGSG------DNITVLVV . | ....|. .| | .|||||.|| .. .| |..|..... |.. ||.| | ... .| ||.||..| kpeeqivtavPDvlvkkldeddeflvLaCDGiWDvltnkevvdlvrerlvsgakldeiieelldkclapdssntgvGcDnmtvviv |
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| Phosphatase | spnA.AA | Subfamily.LRR-PP2C.PD | 702-970 | 31 | 7e-47 | 149.9 | In-house | 9-255 (257) | Show / Hide |
Range on Protein: 702-970 Range on HMM: 9-255/257 Sequence Identity: 31% (85 aa) KLESGFGSLQGRRKNMEDTHVILNNlmgavtYNGPPKDipiSYYAVYDGHGGTETSTLLEPTVHNCLVNSQSFRDGDYEQAFRDAYAEADDIVIEKCEKS ... || . ||| ||| || . ... ... |||..|||||..... .... | . . . ......|| |. . |. | rfkvgfsdmiGrrptmedelviyGs------frdksde---dyyalfdGhgGraaakfaseelykilaelldlnnanPlkslkkaykeistqiserpkfi GSTGVSALLVGNKLYTANVGDSEIVLAraqpnanpkgPVTYEPVLLSYKHLASDDQEKKRVTDLGGMIIFN----RLFGSLAVSRSFGDKeYKEgekKFC .| .|.|....| | |||||| .||. . ||. | |...|.||...|||... . |. | |||||..|| . | | | GttaasvliiedkvyianvGdsrvvlc----------qkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGds-fle---Pfv VSDPYQT-TTDLTARDHFFILACDGLWDKVEYDEAVQFVQRNIklgkSATEISELLAQDSYDRGSGDNITVLVV .||. . . . . .|.|.||||||.|| . .|||. | .. . .| | .| .|| |||.|.|. vpdPdlsqsleiskkdkflilacdGiwdlisdeeaveivagis----dpekaaeklrdlayssGstdnisvivi |
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| Phosphatase | spnA.AA | Subfamily.PPM1L.PD | 708-971 | 32 | 2.3e-38 | 122.1 | In-house | 17-272 (273) | Show / Hide |
Range on Protein: 708-971
Range on HMM: 17-272/273
Sequence Identity: 32% (90 aa)
GSLQGRRKNMEDTHVILNNLMGAVTyngppkdipISYYAVYDGHGGTETS----TLLEPTVHNCLVNSQSF--R--DGDYEQAFRDAYAEADDIVIEKCE
|..|||..||| | ... .. .|..||.||||| .. .| ...| |.. .. . .... . | .| ..|| .
ysvlGrrprmedrfeieediknktg---------esffavfdGhGGefaaefakdvlvkaiknklieldadkentvpinfsklltdeilsvdekllekak
----KSGSTGVSALLVGNKLYTANVGDSEIVLARAQPNANPkgpvtyepvlLSYKHLASDDQEKKRVTDLGGMIIFN---RLFGSLAVSRSFGDKEYKeg
.|.| . ||. ...| |||||| || . .| | ||. | . .|.||. . ||.| |. |.| ||.||..|| | .|
raediaGttalialvqesdlivanvGdsrGvlydkrGkaip----------lsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdyplk--
EKKFCVSDPYQTTTDLTA-RDHFFILACDGLWDKVEYDEAVQFVQRNIKLGKSAteiSELLAQDSYDRGSGDNITVLVVI
.. ..|| | || . .|.|||.||||| .|||.|.. ..| . . |. .|. ||| ||||||||
dknlviadpdiltfdlddhkpeflilasdGlwdtfsneeavrfikerlkepdfG---akslvlesfkrGsvdnitvlvvk
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| Phosphatase | spnA.AA | Subfamily.PPM1G.PD | 797-970 | 34 | 2.3e-29 | 92.9 | In-house | 303-480 (482) | Show / Hide |
Range on Protein: 797-970 Range on HMM: 303-480/482 Sequence Identity: 34% (65 aa) KCEKSGSTGVSALLVGNKLYTANVGDSEIVLARAqpnanpkgpvtYEPVLLSYKHLASDDQEKKRVTDLGGMII-FNRLFGSLAVSRSFGDKEYKEGE-- . . ||.| | ||. |.||. ||.||| ||.|. . . ||. | |..|..|.. || . | | | .|| .||||. | pGkdsGttavvaLvkgkklivanaGDsRcvlsrn-----------GkaldlsiDhkPeDeveleRiekaGGkvtldgRvnGGLnlsRalGDhaYktneeL ---KKFCVSDPYQTTTDLTARDHFFILACDGLWDKVEYDEAVQFVQRNIKLG---KSATEISEL-----LAQDSYDRGSG-DNITVLVV . | .. || |.|..|||||.|. .. .| |.||....| . |. .|| | ||.| . |.| ||.||..| paeeqmisalPDikklilteedeFlvlacDGiWnvmssqevvdFvraklkeseeskklseiceeLlDaCLapdtsgDGtGCDnmtvviv |
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| Phosphatase | spnA.AA | Subfamily.PPM1K.PD | 703-971 | 25 | 1.2e-21 | 67.1 | In-house | 9-263 (264) | Show / Hide |
Range on Protein: 703-971
Range on HMM: 9-263/264
Sequence Identity: 25% (71 aa)
LES-GFGSLQGRRKNMEDTHVIlNNLmgavtyngppkDIPISYYAVYDGHGGTETSTLLEPTVHNCLVNSQsFRDGDYEQAFRDAYAEADDIVIE-----
..| |. ||.|.|.. || . .| | . |.||.|||||. . ..... . .. | |. . .|. | |..
vdsvGkdsliGkraenedrfkl-kel-----------dpdllyfavfdGhgGssaadfvhdkleeivrrll-ekekdleevlkqafeeldkklkrylefs
----KCEKSGSTGVSALL-VGNKLYTANVGDSEIVLARaqpnanpKGpvtyEPVLLSYKHLASDDQEKKRVTDLGGMIIFNR-----LFGSLAVSRSFGD
. ..||.| .|| ||.| |..||| .| | .| .. |. | . ..||.|. ||.. .|. . ||..||.|| . |.
vaeaellssGttatvsllrdGnelvlaslGdsrailcr-------nG----kakkltkdhdPerkeekerikaagGsvewnslgkplvnsrlamtrslGd
KEYKEgekKFCVSDPYQTTTDL-TARDHFFILACDGLWDKVEYDEAVQFVQRNiklgKSATEISELLAQDSYDRGSGDNITVLVVI
...| . .. |.| |..| ||. . |. | ..|. . | .. ... . .|| || |..||
ldlkr---yGviatPetkslkvkhaadsflvlitdgisfvvnsqelcdlvrlc----hdpeeaahavteqalqygsednatavvvp
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| Phosphatase | spnA.AA | Subfamily.PPM1D.PD | 709-870 | 25 | 3.4e-18 | 55.8 | In-house | 14-178 (311) | Show / Hide |
Range on Protein: 709-870
Range on HMM: 14-178/311
Sequence Identity: 25% (44 aa)
SLQGRRKNMEDTHVILNNLMGAVTyngppkDIPISYYAVYDGHGGTETSTLLEPTVHNCLVNSQSFRDG---DYEQAFRDAYAEADDIVIEKCEK-----
. || || |||. .| . . . . .. ||.||||| | .. . . . . . | | .| |.|. . . .| ..
adqGgrkymeDvvaivlereesae------eaeaafvavfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkklaeWpktk
------SGSTGVSALLVGNKLYTANVGDSEIVLARAQPnanpkGPVTYEPVLLSYKHLASDDQEKKRVTDLGGMII
.|.| .. ..|||.|.||||.|||. .| . . .. | | .. .||.|. .||| .
sgllstaGttasvviirreklyvahvGDsgivlgvkep-----kekklrakeltkdHkPespeEkerieelGGeva
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| Phosphatase | spnA.AA | Subfamily.PPM1G.PD | 699-795 | 31 | 7e-16 | 48.4 | In-house | 6-91 (482) | Show / Hide |
Range on Protein: 699-795 Range on HMM: 6-91/482 Sequence Identity: 31% (30 aa) SKIKLESGFGSLQGRRKNMEDTHVILNNLmgavtyngppkDIPISYYAVYDGHGGTETSTLLEPTVHNCLVNSQSFRDGDYEQAFRDAYAEADDIVI |. .|. |. ..|| |..|||.| . .| | .| .||||||||.| .. . . | .|.....|| |.|...|. .|. . sneelsygasamqGWRvsmeDahncildl-----------dedtslfavyDGhGGkevakycakklPdllkeskaykegdvekaleeaflkvDkkll |
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| Phosphatase | spnA.AA | Subfamily.PDP.PD | 796-891 | 32 | 8.3e-12 | 35.0 | In-house | 160-255 (409) | Show / Hide |
Range on Protein: 796-891 Range on HMM: 160-255/409 Sequence Identity: 32% (32 aa) EKCEKSGSTGVSALLVGNKLYTANVGDSEIVLARAQPNANpkgpvtYEPVLLSYKHLASDDQEKKRVTDL------GGMIIFNRLFGSLAVSRSFGDKEY | ||.. . ||. |..|. ||.||. ||.. ..... .|.| || . |. .| .|. .| .|| |.|| .|||| .|| lkvalsGacallaliegtelhvAntGDcravlgvqeeegs------weavkLskdqtadneeEveRikkeHPgeesktvirngRlLgeLaPlRAFGdvry KE Kw |
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| Phosphatase | spnA.AA | Subfamily.TAB1.PD | 800-893 | 37 | 5.9e-11 | 31.8 | In-house | 136-225 (336) | Show / Hide |
Range on Protein: 800-893 Range on HMM: 136-225/336 Sequence Identity: 37% (36 aa) KSGSTGVSALLVGNKLYTANVGDSEIVLARAQPNanpkGpVtyEPVLLSYKHLASDDQEKKRVTDLG---GMIIFNRLFGSLAVSRSFGDKEYKEGE . |.| | ||.. ||||.|||||| .| . ... | . . . || | ..| ||. ||| . | |...|| || || .|.| sgGttavvalilnnkLyvaNvGdsrAilvesekd----g-i--kvkQLsvdHnvdNedElkRlkdLGldieqikqnkrlgskeaTRsiGdykikkgy |
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| Phosphatase | spnA.AA | Subfamily.PPM1D.PD | 878-949 | 33 | 1.7e-10 | 30.5 | In-house | 207-281 (311) | Show / Hide |
Range on Protein: 878-949 Range on HMM: 207-281/311 Sequence Identity: 33% (25 aa) LAVSRSFGDK-EYKEGEKKFCVS-DPYQTTTDLTARDH-FFILACDGLWDKVEYDEAVQFVQRNIKLGKSATEIS |||.|| || |.. ... || .|. . . |. .. | ||| ||||. .. ..||..|... . .. | | LavaRslGDlWsynaksgeyvvsPePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkelkeeqs |
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| Phosphatase | spnA.AA | Subfamily.PHLPP.PD | 744-970 | 23 | 2.1e-10 | 30.1 | In-house | 41-257 (257) | Show / Hide |
Range on Protein: 744-970 Range on HMM: 41-257/257 Sequence Identity: 23% (54 aa) YYAVYDGHGGTETSTLLEPTVHNCLVNSQSFRDGDyEQAFRDAYAEADDIVIEKCEKSGStgvSALLVGNKLYTANVGDSEIVLARAQPNANPKGPVTYE | ..|| .| ..|| |. . | . . . |. ... . .. . |. .| |. ||||. | ..... | . | .. . . |. vyGlidGdrnselpsllqctmadvlkeevqkdkne-evyianillvshrklGeaGqklGa---sallirikedrvdiassftltaanvgkcklvlirnGk PVLLSYKHL-ASDDQEKKRVTDLGGMII-FNRLFGSLAVSRSFGDKEYkegeKKFCVSDPYQTTTDLTARDHFFILACDGLWDKVEYDEAVQFVQRNIKL || . ||.| ||. . ..| |.. | .. .| .| . . .| . || | ..|| ..||.....||||. |... . plplskvyileiddeelkrikeakaiitednkvnGviestrilGytfl----fPvvlPkphvrsvlLteqdEllilGnkalWevlsideaveavrnvedp GKSATEISELLaQdSYDrgSGDNITVLVV | . .|. | ||. .|....||| lvaAkklvdla-q-syg--aadsvsalvv |
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| Phosphatase | spnA.AA | Subfamily.PDP.PD | 900-947 | 33 | 4.1e-09 | 26.2 | In-house | 287-334 (409) | Show / Hide |
Range on Protein: 900-947 Range on HMM: 287-334/409 Sequence Identity: 33% (16 aa) DPYQTTTDLTARDHFFILACDGLWDKVEYDEAVQFVQRNIKLGKSATE .| |. |. .|.|..|| ||||| .. .|.|. |.. .. | .. ePevtshklrendkFLvlatDGLwdllsneevvslVgehlakkknkak |
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| Phosphatase | spnA.AA | Subfamily.PPM1H.PD | 872-940 | 30 | 5.6e-09 | 25.2 | In-house | 277-354 (402) | Show / Hide |
Range on Protein: 872-940 Range on HMM: 277-354/402 Sequence Identity: 30% (24 aa) NRLFGSLAVSRSFGDKEYKEGEKK-----FCVSDPYQTTTDLTA----RDHFFILACDGLWDKVEYDEAVQFVQRNIK .||.. ..|.| .|| | | ... | . | ...||| .|. ||| |||||... .|. . |.. .. aRllatigvtRGlGDheLkvvdtnlsikPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivrevls |
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| Phosphatase | spnA.AA | Subfamily.PPM1H.PD | 782-831 | 37 | 4.4e-06 | 15.7 | In-house | 141-194 (402) | Show / Hide |
Range on Protein: 782-831 Range on HMM: 141-194/402 Sequence Identity: 37% (20 aa) AFRDAYAEADDIVIEKCE----KSGSTGVSALLVGNKLYTANVGDSEIVLARAQ |. .|. | |. . . .| | | | ..||.. .||| || ||| .| | . alesaflemDeqiarereayrikGGCtalvalvllgklYvanaGDsRailvrkd |
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