spnA
Species: D.discoideum
Alias: DDB_G0276155, spnA
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: PPM
Family: PPM
Subfamily: ILKAP
Protein domain

Protein domains of spnA.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
G-alpha spnA.AA G_alpha 55-455 20 4.3e-14 -49.68 SMART 1-400 (400) Show / Hide
Range on Protein: 55-455
Range on HMM: 1-400/400
Sequence Identity: 20% (94 aa)

AQQQKQNEQNLAQLSTSTSSNSSVNNTTNTNTNTTNSSSISSNNNNNNNTAVPILKAHDFCGT-----IMILGHTESGKTTLQRQLEFIYGV-TDPTDAK
... |. .  | . ...  ...                                        .     . .||  ||||.|   |.  |..   .  . |
KRRNKEIDKQLEKDKKKKKKHGQ---------------------------------------SGREVKLLLLGAGESGKSTILKQMRIIHQNGFSQEERK

HYQRLIYGNTLATLIRFIENSERLNITLSPDNL-------ARVKRIQS---QPVELARN---RLPRFPLKLGWDCKCIWEDKVIQSVYNHSKI-----C-
.|. .|| |..  .   |.  |.|||......        .....| .   .. ... .     . ||. .. ..| .| |..||..|. ..      . 
EYRPIIYQNIIQSMRVLIDAMEHLNIPFEDPERENCNENEHHADYIMEYKNYMHDMWEEGCMDEEPFPPEYANAIKALWNDPGIQECYERRNEFQLHDST

---SEIRTPGRPKYYMDRMFKVFDPSYTPTEMDIISAYDQKDTIQSSAIIHKRFKV-------DLFGCSGKQSSPKNWVGLHQN-YKPNYIFYVVALKDY
   ||       ||..|    ..|| | |||.||. ..     ||   .. |...         .| . |  |  | |  .  |    . |...||| .|
IYISE-----YAKYFLDNIDRICDPDYVPTEQDILHCRVPTTGIQETCFEMKNHNFMGVHLQFRMFDVGGQRSERKKWIHCFDNSV--TAIIFCVALSEY

----FSDHLVATQNTDPTIVEMCNNHIHRNLLLESLNSFETLTKSELFDKSLAIYLIFNTSDIFYENIKQY---DLKSCFSEYEGG----------NDPE
    | |  .                  .| . |||| |..   | .| .  .. | .|  |.| | ||.    ... ||..|.|.          || |
DQCLFEDNTT------------------QNRMHESLNLFDSICNSRWFANMTSMILFLNKIDLFEEKIKHVPSNPIHDCFPDYKGPPTPPQDCHCDNDYE

KAVSFISNKFTKFLQ--------NKDKPYKSHIVN-LLDKNNVREEFEGIFDS-LKIDAEKRGF
.|. .| .||    .        |..|.. .|. .   | ||..  |    |. ..   .. |.
EACKYIKWKFRRLNRNRHQRHEQNSKKRIYCHFTCIATDTNNIQFVFDAVKDMIIQNNLKDCGL

Phosphatase spnA.AA PP2Cc 694-970 24 2e-85 291.02 SMART 1-338 (338) Show / Hide
Range on Protein: 694-970
Range on HMM: 1-338/338
Sequence Identity: 24% (92 aa)

NGGVGSKIKLESGF--GSLQGRRKNMEDTHVILNNLMGAVTYNGPPKDIPISYYAVYDGHGGTETSTLLEPTVHNCLVNSQSFRDG--------------
.  .|..... .|.   | ||.|..||| ||. .                  ...|.|||||.|..  .    | .|... .| ..              
HS-MGYNSGWRYGYMESSMQGWRHPMEDAHVCRP------------------FFGVFDGHGGHECAQYCRKHLHEHLAEELQFHKDDDYKENDEMQDEPE

------------DYEQAFRDAYAEADDIVIEKCEKSGSTGVSALLVGNKLYTANVGDSEIVLARAQPNANPKGPV-TYEPVLLSYKHLASDDQEKKRVTD
            | | |.|.|. ..|.          .| | ||..|||||.|||||| .|| |.. . |..| . .|... |.. | ...  |..|. .
MWWRMWHDKWFEDWEDALRKAFLRMDEEI--------CTAVVALIRGNKLYVANVGDSRAVLCRNGND-NWWG-IRHYTAHQLTEDHKPDNEDERRRIEQ

LGG--------MIIFN-----RLFGS---LAVSRSFGDKEYK--------------------EGEKKFCVSDPYQTTTDL------TARDHFFILACDGL
.||         ....     |..|.   |||||.|||..||                    .... . ...|. |...|      |  | |.||.||||
AGGRVMPMHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKWKEDEKIEWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQMTVPTPDDDFLILCCDGL

WDKVEYDEAVQFVQRNI-----------------------KLGKSATEISELLAQDSYDRGSGDNITVLVV
||.....|.|..|....                       |  ... |....|..  .     ||.||.||
WDVMSNQEVVDIVRKCLRKWHHKPVKNQAQENAHMMRHRQKKHNDPMEAAKRLCDCAI----CDNMTVIVV

G-alpha spnA.AA G-alpha 376-436 33 8e-06 20.55 Pfam 270-340 (360) Show / Hide
Range on Protein: 376-436
Range on HMM: 270-340/360
Sequence Identity: 33% (24 aa)

DIFYENIKQYD--LKSCFSEYE----GG-NDPEKAVSFISNKFTKFLQNKD---KPYKSHIVNLLDKNNVR
|.| | ||  .  .. || .|.    |. .| | |. ||  ||    ||..   |.  .|.    |.||.|
DLFEEKIKHTPSHISDCFPDYKDYQQGPPQDYEWACNFIKQKFWSLNQNNEKPDKEIYHHFTCATDTNNIR

Phosphatase spnA.AA PP2C 703-965 31 1.4e-99 341.92 Pfam 1-284 (284) Show / Hide
Range on Protein: 703-965
Range on HMM: 1-284/284
Sequence Identity: 31% (92 aa)

LESGFGSLQGRRKNMEDTHVILNNLMGAVTYNGPPKDIPISYYAVYDGHGGTETSTLLEPTVH----NCLVNSQSFRDG---DYEQAFRDAYAE-ADDIV
...||...||.|. |||.|....|..       .  .......||.|||||.....  . ..|    ..| . .||..|   |.|||.|....| . |..
WDYGFCRMQGWRHFMEDAHHCYPNMNCS-----SSGKDSWHFFAVFDGHGGHQAAKYCRKHLHKAMNTILKERKSFPEGNPKDVEQALRKSFLECDTDMM

IEK------------CEKSGSTGVSALLVGNK--LYTANVGDSEIVLARAQPNANPKGPVTYEPVLLSYKHLASDDQEKKRVTDLGGMII---FNRLFGS
. .            |..||.| |.|.....|  ||.||.||| .||.|..  .|.       ...|.|.| .|...|..|....||...   |.|..|.
FYSAPWHEQNVMHWECWHSGCTAVCAYIRNQKNILYVANCGDSRAVLCRNGNAHNW-------VHQLTYDHKPSNEDERRRIRQAGGWVMWWGFWRVNGV

-LAVSRSFGDKEYKEGE-----KKFCVSDPYQT-TTDLTAR-DHFFILACDGLWDKVEYDEAVQFVQRNIKLGKSATEISELLAQDSYDRGSGDNI
 |||||.|||..|| ..     .. ....|. | ....|   |.|.|||||||||.....|....|..... .....|..| |.......|| |||
WLAVSRAFGDFHYKPNHTCFPKEQPVTAEPDITPEHKITPDHDEFLILACDGLWDVMSDQEVCDIVRQCRSDWNDPMEACEKLVDYCIAYGSEDNI

Phosphatase spnA.AA Subfamily.ILKAP.PD 699-970 38 4.1e-98 318.3 In-house 5-298 (298) Show / Hide
Range on Protein: 699-970
Range on HMM: 5-298/298
Sequence Identity: 38% (114 aa)

SKIKLESGFGSLQGRRKNMEDTHVILNNLMGAvTYNGPPKDIPISYYAVYDGHGGTETSTLLEPTVHNCLV-----NSQSFRDGDYEQAFRDAYAEADDI
||.|||..|....|.|..|||.|||||.|. . |... .| ...|||||.|||.|...|.... ..|...|     ...|..| .......||....|. 
skyklegafaerkGereemeDahvilndldeq-trkekskvsrvsyyavfDGhaGsrasefaaeklhkviveklpkedvsakdkeikkclvdafkktDee

VIEKCE------KSGSTGVSALLVGNKLYTANVGDSEIVLARAQPNANPKGPVTYEPVLLSYKHLASDDQEKKRVTDLGGMIIFNRLFGSLAVSRSFGDK
......      |.|||.|..|.|.|.||.||.|||..|||||..... .|..|...||||..| .....|.||... ||.....|..|.|.||||.||.
flklaskakPvWkdGstavvvlvvdnvlyvanlGDskavlaRakeegdkagestiasvlLskdHtpasyeerkriqkaGgvvrdgRvlGvlevsRsiGDg

EYKEGEkkfCVSDPYQTTTDLTARDHFFILACDGLWDKVEYDEAVQFV----------QRNIKLGKSATEI-----SELLAQDSYDRGSGDNITVLVV
..|| .   ..|.|......||..|.|..|||||||...|.||.|.|.          ... . ||||.|..| ||.....|||.||.|||.|     
rfkelg---vistPdvkkceLtenDlfvvlaCDGLwkvfeadevvkfilkvlededdrkikqeegksaeevrfevacerlAseavkrgssDnvtvllv

Phosphatase spnA.AA Group.PPM.PD 699-973 34 1.7e-70 227.8 In-house 34-322 (459) Show / Hide
Range on Protein: 699-973
Range on HMM: 34-322/459
Sequence Identity: 34% (99 aa)

SKIKLESGFGSLQGRRKNMEDTHVILNNLMGAVtyngppkdipiSYYAVYDGHGGTETSTLLEPTVHNCLVNSQSFRD------------------GDYE
|. .|  |. | ||.||.|||.||| .|.               |...|.|||||.| . . . . ...| .. .. .....|.|.|. | |.   |...
sgnglrygvasmqgwrkemEDrhvivenfdnnd-----------sffgVfDGHgGaeaaefaakkLpkilkkqlkkkkdevskksaeasldnddrgekvk

QAFRDAYAEADDIVIEKCEK-------SGSTGVSALLVGNKLYTANVGDSEIVLARAQpnanpkgpvtyEPVLLSYKHLASDDQEKKRVTDLGGMIIF-N
.       ||.| |.||. |.|||.||.||| .|| |..           ..| ||. |  ....|..|....||.   .|. |.|||||..|| ..|. 
kalrsafleldedlseeanekeepgkdsGtTAvvalingkklyvANaGDSravLcrng-----------kavplskdHkpenpeEreRIekagGsveidg

RLFGSLAVSRSFGDKEYKEgEKKFCVSDPYQTTTDLTARDHFFILACDGLWDKVEYDEAVQFVQRNIKL-----GKSATEISELLAQDSYDRGSG-----
|. .  ..|. .. .||  |.|..||.||||| .. .|.|.||.....      .|...||.| |... ..||       |||||.|| ||         
RvnGilavsRalGdhdlkk-eeqmvsaePdvsvvklteedeflvlAsDGlWdvlsneevvefvretlekkkkelkkdleeiaerlvdealakgstgdgts

-DNITVLVVILN
            
cDNiTvivvtln

Phosphatase spnA.AA Family.PPM.PD 699-973 33 8.7e-68 218.8 In-house 11-287 (495) Show / Hide
Range on Protein: 699-973
Range on HMM: 11-287/495
Sequence Identity: 33% (98 aa)

SKIKLESGFGSLQGRRKNMEDTHVILNNLMGAVtyngppkdiPISYYAVYDGHGGTETSTLLEPTVHNCLVNSQSFRD------------GDYEQAFRDA
|. .|. |. | ||.|..|||.||...|| . .         ..|...|.|||||.| . . . . |..| ..... |             ....|.|.|
ssnglrygvasmqgwrsemeDahvvvenlenne---------dfslfgvfDGhgGaeaaefaakklhkilkkqlekkddeksstsaessaekvkealrka

YAEADDIVIEKCE------KSGSTGVSALLVGNKLYTANVGDSEIVLARAQpnanpkgpvtyEPVLLSYKHLASDDQEKKRVTDLGGMIIF--NRLFGSL
. | |  . |...      .||.| |..|. |.|||.||.|||..|| |..           ..| ||..|  ....|..|....|| ..|. |.|||||
fleldeelseelneksagkdsGtTAvvvlirgkklyvAnaGDsravLcrng-----------kavelskdHkpenpeEreRIekagGkvvirdgrvnGvl

AVSRSFGDKEYKEGEKKFCVSDPYQTTTDLT-ARDHFFILACDGLWDKVEYDEAVQFVQRNI-KLGKSATEISELLAQDSYDRGSGDNITVLVVILN
..|| ..|. |. . ...|. |...||   |.|..||.||||| .. .|.|..|.... . .....||.| | .  . .||.|||||||| |.    
avsRalGdfdlkkeeqaivsaePditsvkltqeedeflvlasdGlWdvlsneevvelvretleekeedleeiaeeLvdealakgsrDNiTvlvvaly

Phosphatase spnA.AA Subfamily.PPM1A.PD 700-972 31 3.1e-57 184.1 In-house 7-278 (309) Show / Hide
Range on Protein: 700-972
Range on HMM: 7-278/309
Sequence Identity: 31% (90 aa)

KIKLESGFGSLQGRRKNMEDTHVILNNLMGAVtyngppKDipISYYAVYDGHGGTETSTLLEPTVHNCLVNSQSFR-------DGDYEQAFRDAYAEADD
. .|  |  | || | .|||.|..  .| ...      ||   |..||.|||.|.. |.  . .... ......|.         ....|.|... |.|.
gnglryglssmqgwRvemEDahtavidlpskl------kd--wsffavfDGHaGskvskycakhlleaileeeefkaskeksskekvkealrkgfLelDe

IVI-----EKC-EKSGSTGVSALLVGNKLYTANVGDSEIVLARAQpnanpkgpvtyEPVLLSYKHLASDDQEKKRVTDLGGMIIFNRLFGSLAVSRSFGD
 .      .|. .||||| |..|.  .|||.||.||| .||.|..           . |  .. | .||..||.|... ||... .|. |||||||..||
kirklvelskgedksGsTavvvlvspkklylancGDsRavlsrng-----------kvvfateDHkpsdpkEkeRienAgGsvmikRvnGsLAvsRalGD

KEYKEG-----EKKFCVSDPYQTTTDLTARDHFFILACDGLWDKVEYDEAVQFVQRNIKLGKSATEISELLAQDSYDRGSGDNITVLVVIL
..|||      ...  ...|. |... .. |.|..|||||.|| .. .|...||........ ..|... | ..  .|| ||..|..|.| 
ydykekpekkateqlvspepevtvierdeedeflvlacDGiwDvmsneevaefvksrlevtddleevanelldtcLekgsrDNmsvilvll

Phosphatase spnA.AA Subfamily.PPM1E.PD 709-972 32 2.2e-54 174.4 In-house 17-269 (269) Show / Hide
Range on Protein: 709-972
Range on HMM: 17-269/269
Sequence Identity: 32% (86 aa)

SLQGRRKNMEDTHVILNNLMGAVTYngpPKDIPISYYAVYDGHGGTETSTLLEPTVHNCLVNSQSFRDgDYEQAFRDAYAEADDIVIEK----CEKSGST
.....|. ||| ||.|..|   .      .. .....||.|||||.|...     .|. ||. ... . | ..|...|. ..|. ...|. |||||.|..
avknkrrkmEDrhvaledlnelfel---kdekeraffavfDGHgGveaakyaaahlhellvrqeklke-dpaealkeafkltDerflqkaereklksGst

GVSALLVGNKLYTANVGDSEIVLARAQpnanpkgpvtyEPVLLSYKHLASDDQEKKRVTDLGGMIIF---NRLFGSLAVSRSFGDKEYkegeKKFCVSDP
|. ...|| | .|||. .| | .           | | |   |  ....||||. ..||....    |  |.|.|||.||...    |.. ....  ...
avvvliekdqlyvaWlGDsqallvrkg-----------eavqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRaiGDvkl----kpyvsgea

YQTTTDLTARDHFFILACDGLWDKVEYDEAVQFVQRNIKLGK-SATEISELLAQDSYDRGSGDNITVLVVIL
.|.  ... ||||||||| |. .|.|. |.  .. |. . .|...|| . ....|| |||||.||.|     
dvaeveldgsedylilacDGlwDvvneeevvklveefladgaedlsevakllveaakeagssDnitvvvvfl

Phosphatase spnA.AA Subfamily.PPM1G2.PD 700-970 31 1.6e-50 161.7 In-house 7-275 (275) Show / Hide
Range on Protein: 700-970
Range on HMM: 7-275/275
Sequence Identity: 31% (90 aa)

KIKLESGFGSLQGRRKNMEDTHVILNNLMGAvtyngpPKDIPISYYAVYDGHGGTETSTLLEPTVHNCLVNSQSFRDGDYEQAFRDAYAEADDIVIEK--
. ... | .|.|| | ||||.|.. |.|.        . |  ....||.|||||.. .      ... ... .||..|  ||...||. ||  ....   
nariavgvssmqGyrlnmeDahilenellek------sddkslalfavfDGhGGakvakyagkklikkiakkksfkegaleqilkdafletDeellkdek

--CEKSGSTGVSALLVGNKLYTANVGDSEIVLARAQPnANPkgpvtyepvlLSYKHLASDDQEKKRVTDLGGMIIFNRLFGSLAVSRSFGDKEYKEGE--
  |..||| |..|.  .||| ||.|||  ||. .   ..           ||. |  .. .||||... ||.. .|||.||.||..|| |.|...     
lkdesaGstavvvlikeeklyvanaGDsravlsskgn-vka----------lsfDhkPqeesekkriiaagGfvelnrvngnLalsralgDfefkknvkk

---KKFCVSDPYQTTTDLTARDHFFILACDGLWDKVEYDEAVQFVQRNIKLGKSATEISELLAQDSYDRGSG------DNITVLVV
 .     |  ....|. .| | .|||||.|| .. .| |..|..... |..  ||.| | ...  .|       ||.||..|    
kpeeqivtavPDvlvkkldeddeflvLaCDGiWDvltnkevvdlvrerlvsgakldeiieelldkclapdssntgvGcDnmtvviv

Phosphatase spnA.AA Subfamily.LRR-PP2C.PD 702-970 31 7e-47 149.9 In-house 9-255 (257) Show / Hide
Range on Protein: 702-970
Range on HMM: 9-255/257
Sequence Identity: 31% (85 aa)

KLESGFGSLQGRRKNMEDTHVILNNlmgavtYNGPPKDipiSYYAVYDGHGGTETSTLLEPTVHNCLVNSQSFRDGDYEQAFRDAYAEADDIVIEKCEKS
... ||  . |||  |||  ||  .      ... ...    |||..|||||.....    .... | .     . . ......|| |.  . |.    |
rfkvgfsdmiGrrptmedelviyGs------frdksde---dyyalfdGhgGraaakfaseelykilaelldlnnanPlkslkkaykeistqiserpkfi

GSTGVSALLVGNKLYTANVGDSEIVLAraqpnanpkgPVTYEPVLLSYKHLASDDQEKKRVTDLGGMIIFN----RLFGSLAVSRSFGDKeYKEgekKFC
.| .|.|....| | |||||| .||.                . ||. |  |...|.||...|||... .    |. | |||||..||  . |    | |
GttaasvliiedkvyianvGdsrvvlc----------qkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGds-fle---Pfv

VSDPYQT-TTDLTARDHFFILACDGLWDKVEYDEAVQFVQRNIklgkSATEISELLAQDSYDRGSGDNITVLVV
.||. . . . . .|.|.||||||.|| .  .|||. |        .. . .| |   .| .|| |||.|.|. 
vpdPdlsqsleiskkdkflilacdGiwdlisdeeaveivagis----dpekaaeklrdlayssGstdnisvivi

Phosphatase spnA.AA Subfamily.PPM1L.PD 708-971 32 2.3e-38 122.1 In-house 17-272 (273) Show / Hide
Range on Protein: 708-971
Range on HMM: 17-272/273
Sequence Identity: 32% (90 aa)

GSLQGRRKNMEDTHVILNNLMGAVTyngppkdipISYYAVYDGHGGTETS----TLLEPTVHNCLVNSQSF--R--DGDYEQAFRDAYAEADDIVIEKCE
|..|||..|||   | ...   ..         .|..||.|||||  ..     .|  ...| |.. ..   .    .... . |    .|  ..|| . 
ysvlGrrprmedrfeieediknktg---------esffavfdGhGGefaaefakdvlvkaiknklieldadkentvpinfsklltdeilsvdekllekak

----KSGSTGVSALLVGNKLYTANVGDSEIVLARAQPNANPkgpvtyepvlLSYKHLASDDQEKKRVTDLGGMIIFN---RLFGSLAVSRSFGDKEYKeg
    .|.| . ||. ...|  ||||||  ||   . .| |          ||. |   . .|.||. . ||.| |.   |.| ||.||..||   |  .|
raediaGttalialvqesdlivanvGdsrGvlydkrGkaip----------lsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdyplk--

EKKFCVSDPYQTTTDLTA-RDHFFILACDGLWDKVEYDEAVQFVQRNIKLGKSAteiSELLAQDSYDRGSGDNITVLVVI
.. ..||   | ||   . .|.|||.|||||    .|||.|.. ..|  .     .  |. .|. ||| ||||||||   
dknlviadpdiltfdlddhkpeflilasdGlwdtfsneeavrfikerlkepdfG---akslvlesfkrGsvdnitvlvvk

Phosphatase spnA.AA Subfamily.PPM1G.PD 797-970 34 2.3e-29 92.9 In-house 303-480 (482) Show / Hide
Range on Protein: 797-970
Range on HMM: 303-480/482
Sequence Identity: 34% (65 aa)

KCEKSGSTGVSALLVGNKLYTANVGDSEIVLARAqpnanpkgpvtYEPVLLSYKHLASDDQEKKRVTDLGGMII-FNRLFGSLAVSRSFGDKEYKEGE--
. . ||.| | ||. |.||. ||.|||  ||.|.            . . ||. |   |..|..|..  || .    |  | | .|| .||||. |    
pGkdsGttavvaLvkgkklivanaGDsRcvlsrn-----------GkaldlsiDhkPeDeveleRiekaGGkvtldgRvnGGLnlsRalGDhaYktneeL

---KKFCVSDPYQTTTDLTARDHFFILACDGLWDKVEYDEAVQFVQRNIKLG---KSATEISEL-----LAQDSYDRGSG-DNITVLVV
  .     |   .. ||  |.|..|||||.|. .. .| |.||....| .   |. .|| |      ||.|  . |.| ||.||..|  
paeeqmisalPDikklilteedeFlvlacDGiWnvmssqevvdFvraklkeseeskklseiceeLlDaCLapdtsgDGtGCDnmtvviv

Phosphatase spnA.AA Subfamily.PPM1K.PD 703-971 25 1.2e-21 67.1 In-house 9-263 (264) Show / Hide
Range on Protein: 703-971
Range on HMM: 9-263/264
Sequence Identity: 25% (71 aa)

LES-GFGSLQGRRKNMEDTHVIlNNLmgavtyngppkDIPISYYAVYDGHGGTETSTLLEPTVHNCLVNSQsFRDGDYEQAFRDAYAEADDIVIE-----
..| |. ||.|.|.. ||   .  .|           |  . |.||.|||||. .       ..... .    .. | |. . .|. | |..        
vdsvGkdsliGkraenedrfkl-kel-----------dpdllyfavfdGhgGssaadfvhdkleeivrrll-ekekdleevlkqafeeldkklkrylefs

----KCEKSGSTGVSALL-VGNKLYTANVGDSEIVLARaqpnanpKGpvtyEPVLLSYKHLASDDQEKKRVTDLGGMIIFNR-----LFGSLAVSRSFGD
   . ..||.|   .||  ||.|  |..|||  .| |       .|    ..  |.  |  . ..||.|.   ||.. .|. . ||..||.|| . |.  
vaeaellssGttatvsllrdGnelvlaslGdsrailcr-------nG----kakkltkdhdPerkeekerikaagGsvewnslgkplvnsrlamtrslGd

KEYKEgekKFCVSDPYQTTTDL-TARDHFFILACDGLWDKVEYDEAVQFVQRNiklgKSATEISELLAQDSYDRGSGDNITVLVVI
    ...|   . ..  |.| |..|  ||. . |.  |  ..|.      .   | .. ... . .|| || |..||         
ldlkr---yGviatPetkslkvkhaadsflvlitdgisfvvnsqelcdlvrlc----hdpeeaahavteqalqygsednatavvvp

Phosphatase spnA.AA Subfamily.PPM1D.PD 709-870 25 3.4e-18 55.8 In-house 14-178 (311) Show / Hide
Range on Protein: 709-870
Range on HMM: 14-178/311
Sequence Identity: 25% (44 aa)

SLQGRRKNMEDTHVILNNLMGAVTyngppkDIPISYYAVYDGHGGTETSTLLEPTVHNCLVNSQSFRDG---DYEQAFRDAYAEADDIVIEKCEK-----
. || || |||. .|  .   . .      .   .. ||.||||| | ..     . . . . . |      |  .| |.|. .    . .| ..     
adqGgrkymeDvvaivlereesae------eaeaafvavfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkklaeWpktk

------SGSTGVSALLVGNKLYTANVGDSEIVLARAQPnanpkGPVTYEPVLLSYKHLASDDQEKKRVTDLGGMII
      .|.|    .. ..|||.|.||||.|||.  .|     .  . ..  |   |  .. .||.|. .||| . 
sgllstaGttasvviirreklyvahvGDsgivlgvkep-----kekklrakeltkdHkPespeEkerieelGGeva

Phosphatase spnA.AA Subfamily.PPM1G.PD 699-795 31 7e-16 48.4 In-house 6-91 (482) Show / Hide
Range on Protein: 699-795
Range on HMM: 6-91/482
Sequence Identity: 31% (30 aa)

SKIKLESGFGSLQGRRKNMEDTHVILNNLmgavtyngppkDIPISYYAVYDGHGGTETSTLLEPTVHNCLVNSQSFRDGDYEQAFRDAYAEADDIVI
|. .|. |. ..|| |..|||.|  . .|           |  .| .||||||||.| ..     . . | .|.....|| |.|...|. .|. .  
sneelsygasamqGWRvsmeDahncildl-----------dedtslfavyDGhGGkevakycakklPdllkeskaykegdvekaleeaflkvDkkll

Phosphatase spnA.AA Subfamily.PDP.PD 796-891 32 8.3e-12 35.0 In-house 160-255 (409) Show / Hide
Range on Protein: 796-891
Range on HMM: 160-255/409
Sequence Identity: 32% (32 aa)

EKCEKSGSTGVSALLVGNKLYTANVGDSEIVLARAQPNANpkgpvtYEPVLLSYKHLASDDQEKKRVTDL------GGMIIFNRLFGSLAVSRSFGDKEY
|   ||.. . ||. |..|. ||.||.  ||.. .....      .|.| ||  . |.  .| .|.           .|  .|| |.|| .|||| .|| 
lkvalsGacallaliegtelhvAntGDcravlgvqeeegs------weavkLskdqtadneeEveRikkeHPgeesktvirngRlLgeLaPlRAFGdvry

KE
  
Kw

Phosphatase spnA.AA Subfamily.TAB1.PD 800-893 37 5.9e-11 31.8 In-house 136-225 (336) Show / Hide
Range on Protein: 800-893
Range on HMM: 136-225/336
Sequence Identity: 37% (36 aa)

KSGSTGVSALLVGNKLYTANVGDSEIVLARAQPNanpkGpVtyEPVLLSYKHLASDDQEKKRVTDLG---GMIIFNRLFGSLAVSRSFGDKEYKEGE
. |.| | ||.. ||||.||||||  .| . ...    | .  . . ||  |    ..| ||. |||   . |  |...||    || || .|.|  
sgGttavvalilnnkLyvaNvGdsrAilvesekd----g-i--kvkQLsvdHnvdNedElkRlkdLGldieqikqnkrlgskeaTRsiGdykikkgy

Phosphatase spnA.AA Subfamily.PPM1D.PD 878-949 33 1.7e-10 30.5 In-house 207-281 (311) Show / Hide
Range on Protein: 878-949
Range on HMM: 207-281/311
Sequence Identity: 33% (25 aa)

LAVSRSFGDK-EYKEGEKKFCVS-DPYQTTTDLTARDH-FFILACDGLWDKVEYDEAVQFVQRNIKLGKSATEIS
|||.|| ||   |..  ... || .|. . . |.  .. | ||| ||||. .. ..||..|... . ..   | |
LavaRslGDlWsynaksgeyvvsPePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkelkeeqs

Phosphatase spnA.AA Subfamily.PHLPP.PD 744-970 23 2.1e-10 30.1 In-house 41-257 (257) Show / Hide
Range on Protein: 744-970
Range on HMM: 41-257/257
Sequence Identity: 23% (54 aa)

YYAVYDGHGGTETSTLLEPTVHNCLVNSQSFRDGDyEQAFRDAYAEADDIVIEKCEKSGStgvSALLVGNKLYTANVGDSEIVLARAQPNANPKGPVTYE
| ..||   .| ..||  |. . | .  .    . |. ... .  ..  . |. .| |.   ||||.  |  ..... |  . |    .. .  .   |.
vyGlidGdrnselpsllqctmadvlkeevqkdkne-evyianillvshrklGeaGqklGa---sallirikedrvdiassftltaanvgkcklvlirnGk

PVLLSYKHL-ASDDQEKKRVTDLGGMII-FNRLFGSLAVSRSFGDKEYkegeKKFCVSDPYQTTTDLTARDHFFILACDGLWDKVEYDEAVQFVQRNIKL
 ||  .    ||.| ||. .  ..|   |.. | .. .| .|          . . .|    . ||  | ..||  ..||.....||||. |... .   
plplskvyileiddeelkrikeakaiitednkvnGviestrilGytfl----fPvvlPkphvrsvlLteqdEllilGnkalWevlsideaveavrnvedp

GKSATEISELLaQdSYDrgSGDNITVLVV
 |  . .|. | ||.   .|....|||  
lvaAkklvdla-q-syg--aadsvsalvv

Phosphatase spnA.AA Subfamily.PDP.PD 900-947 33 4.1e-09 26.2 In-house 287-334 (409) Show / Hide
Range on Protein: 900-947
Range on HMM: 287-334/409
Sequence Identity: 33% (16 aa)

DPYQTTTDLTARDHFFILACDGLWDKVEYDEAVQFVQRNIKLGKSATE
.|  |.  |. .|.|..|| ||||| .. .|.|. |.. ..  |  ..
ePevtshklrendkFLvlatDGLwdllsneevvslVgehlakkknkak

Phosphatase spnA.AA Subfamily.PPM1H.PD 872-940 30 5.6e-09 25.2 In-house 277-354 (402) Show / Hide
Range on Protein: 872-940
Range on HMM: 277-354/402
Sequence Identity: 30% (24 aa)

NRLFGSLAVSRSFGDKEYKEGEKK-----FCVSDPYQTTTDLTA----RDHFFILACDGLWDKVEYDEAVQFVQRNIK
.||.. ..|.| .|| | |  ...     |  . |  ...|||     .|.  ||| |||||... .|. . |.. ..
aRllatigvtRGlGDheLkvvdtnlsikPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivrevls

Phosphatase spnA.AA Subfamily.PPM1H.PD 782-831 37 4.4e-06 15.7 In-house 141-194 (402) Show / Hide
Range on Protein: 782-831
Range on HMM: 141-194/402
Sequence Identity: 37% (20 aa)

AFRDAYAEADDIVIEKCE----KSGSTGVSALLVGNKLYTANVGDSEIVLARAQ
|. .|. | |. . . .|    | | | ..||.. .||| || |||  .| | .
alesaflemDeqiarereayrikGGCtalvalvllgklYvanaGDsRailvrkd

Sequence
Name Sequence Type Origin Length Description Download
spnA.AA Protein None 975 None Fasta, JSON
spnA.NA RNA None 2928 None Fasta, JSON
spnA.AA.PD_694-970 Protein Phosphatase Domain None 277 None Fasta, JSON