pppB
Species: D.discoideum
Alias: DDB_G0275619, pppB
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: PPP
Family: PPP
Subfamily: PPP1C
Protein domain

Protein domains of pppB.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase pppB.AA Family.PPP.PD 25-300 56 9.40000000001e-135 439.2 In-house 67-344 (349) Show / Hide
Range on Protein: 25-300
Range on HMM: 67-344/349
Sequence Identity: 56% (156 aa)

DLAEEEIRYLTVQATEIFINQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPQS-NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHEC
.| ..|.  |  .|.|.. ..|.|||.||||..|||||||..||||||. .|.||.. .||||||||||||.|.|.|.||.|.|..||..||.||||||.
qleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsrffllRGnhEs

ASINRIYGFYDECKRRY--NSKLWKAFTDCFNCLPVAAIIDEKIFCMHGGLSPDLKNMDQIRRITRPTVVPDFGLLCDLLWADPDKnIQGWEDNDRGVSY
.|.|..||||.|.|..|  .......|...||.||.||.|||||.|.||||||.|...||||.| ||. .|. ||||||||.||..  .||.|.|||...
rsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdpee-qkgwkpnkRGvgf

TFGADVVESFLKKHDLDLVCRAHQVVEDGYEFFAKRQLVTLFSAPNYFGEFDNAGAMMGVDETLMCSFQILKPADKKKL
||.|.|| ||||..|||..|||.|||.||||||.|.|||.|||||| ||..|..|.. ||..|..|....||...|   
vFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskhklr

Phosphatase pppB.AA Subfamily.PPP1C.PD 26-295 84 2.9e-167 544.9 In-house 1-270 (271) Show / Hide
Range on Protein: 26-295
Range on HMM: 1-270/271
Sequence Identity: 84% (228 aa)

LAEEEIRYLTVQATEIFINQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPQSNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECAS
|.|.|||.|...| |||..||||||||||.||.|||||||.|||||||.|||||.||||||||||||||||||||.||||||||||||||.|||||||||
lkeaeirklclkareiflsqpilleleaplkivGdihGqyadllrlfekggfppesnylflGdyvdrGkqsletivlllaykikypenffllrGnhecas

INRIYGFYDECKRRYNSKLWKAFTDCFNCLPVAAIIDEKIFCMHGGLSPDLKNMDQIRRITRPTVVPDFGLLCDLLWADPDKNIQGWEDNDRGVSYTFGA
|||||||||||||||| ||||.|.|||||||||||.||||||.|||||||||...|||||.||| ||| ||||||||.||||...||..||||||.||||
inriygfydeckrryniklwktfvdcfnclpvaaivdekifcvhGGlspdlksleqirriarptdvpdkGllcdllwsdpdkevkgwgendrgvsftfga

DVVESFLKKHDLDLVCRAHQVVEDGYEFFAKRQLVTLFSAPNYFGEFDNAGAMMGVDETLMCSFQILKPA
||||.|||||||||..||||||||||||||||||||||||||| ||||||||.| |||.|.|||||||||
dvvekflkkhdldlivrahqvvedgyeffakrqlvtlfsapnycgefdnagavmsvdeellcsfqilkpa

Phosphatase pppB.AA PP2Ac 26-296 47 1.7e-163 550.37 SMART 1-321 (321) Show / Hide
Range on Protein: 26-296
Range on HMM: 1-321/321
Sequence Identity: 47% (153 aa)

LAEEEIRYLTVQATEIFINQPILLELE----APIKICGDIHGQYYDLLRLF---EYGG-FPPQSNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFIL
....||. |  .. |||  .| ..|.|    .|...|||||||..||||||   . .| .||..||.|||||||||..|.|.||||..|||.||.|||.|
MHKHEIYQLCHEVKEIFRQEPNMVEVEETPTPPVTVCGDIHGQFDDLLRLFKKEDKNGKPPPYTNYVFLGDYVDRGPWSIECICLLFCYKICYPNNFFLL

RGNHECASIN---RIYGFYDECKRRY-NSKLWKAFTDCFNCLPVAAIIDEKIFCMHGGLSP------DLKNMDQIRRITR----PTVVPDFGLLCDLLWA
|||||| ..|   ..|||||||||.| . ..|| |..||...|..|.|. ||.||||||||      .... |.||.| |    |   ||.||.|||||.
RGNHECRHMNMWVQYYGFYDECKRKYYHKRIWKIFQECFSWMPLCALINNKILCMHGGLSPRECQTDHIHTLDDIRNIDRPQHPPQEPPDWGLMCDLLWS

DP--------DKNIQGWEDND-RGVSYTFGADVVESFLKKHDLDLVCRAHQVVE----DGYEFFAKR-----QLVTLFSAPNYFGEFDNAGAMMGV----
||        |.. .||  |  ||.||.||.|||. |.||..|||..||||.|.    |||||...|     .|.|.|||||| ...||..|.| |    
DPVDFQWFHDDQWVPGWQPNCMRGMSYYFGPDVVDEFCKKNNLDLIIRAHQCVQYQMMDGYEFWHDRDTRVHKLITIFSAPNYCDQCDNHAAVMKVNDHK

------DETLMCSFQILKPAD
      |. |.|.|. .||. 
VIQYKMDKNLKCHFVQFKPQM

Phosphatase pppB.AA Subfamily.PPP_Nematode_6.PD 28-295 61 1.5e-135 440.5 In-house 3-271 (272) Show / Hide
Range on Protein: 28-295
Range on HMM: 3-271/272
Sequence Identity: 61% (164 aa)

EEEIRYLTVQATEIFINQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPQSNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASIN
|||.  |. .|...| .|. |.|.|||||.|||||||| ||||||. |||||..||||||||||||.||||.|.||||||.|.|.|||.|||||||..||
eeellkllelakkvfkkqkslveveapikvcGdihGqysdllrlfdkggfppdanylflGdyvdrGrqslevillllaykvkfpnnffllrGnheceain

RIYGFYDECKRRYN-SKLWKAFTDCFNCLPVAAIIDEKIFCMHGGLSPDLKNMDQIRRITRPTVVPDFGLLCDLLWADPDKNIQGWEDNDRGVSYTFGAD
|.||||||..|||. ..|..|| ..|| ||..|.. ..|.|||||||. ||..||.|...||...  |  ||||.||.....||..| ||||..||.|.|
rvyGfydevqrrykstrlyaafqevfnalpltalvsgrilcmhGGlskklksldqlrelkrpldskeeslaidllwsdpenavkgwaensrGvsvvfGed

VVESFLKKHDLDLVCRAHQVVEDGYEFFAKRQLVTLFSAPNYFGEFDNAGAMMGVDETLMCSFQILKPA
...|.| |.|||.||||||.|||||||...|||.||||.| |.|||| |.| ||| |..||..|||.  
avkkllekldidlvarahqvvqdGyeffaekklvtifsaphycgqfdnaaavmkvdeklvvsfevlkpe

Phosphatase pppB.AA Group.PPP.PD 25-300 56 9.40000000001e-135 439.2 In-house 67-344 (349) Show / Hide
Range on Protein: 25-300
Range on HMM: 67-344/349
Sequence Identity: 56% (156 aa)

DLAEEEIRYLTVQATEIFINQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPQS-NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHEC
.| ..|.  |  .|.|.. ..|.|||.||||..|||||||..||||||. .|.||.. .||||||||||||.|.|.|.||.|.|..||..||.||||||.
qleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsrffllRGnhEs

ASINRIYGFYDECKRRY--NSKLWKAFTDCFNCLPVAAIIDEKIFCMHGGLSPDLKNMDQIRRITRPTVVPDFGLLCDLLWADPDKnIQGWEDNDRGVSY
.|.|..||||.|.|..|  .......|...||.||.||.|||||.|.||||||.|...||||.| ||. .|. ||||||||.||..  .||. |.|||..
rsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdpee-qkgwkpnkRGvgf

TFGADVVESFLKKHDLDLVCRAHQVVEDGYEFFAKRQLVTLFSAPNYFGEFDNAGAMMGVDETLMCSFQILKPADKKKL
.||.|.|| ||||..|||..|||.|||.||||||.|.|||.|||||| ||..|..|.. ||..|..|....||...|  
vFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskhklr

Phosphatase pppB.AA Subfamily.PPP_Nematode_4.PD 28-295 50 2.2e-104 338.4 In-house 3-270 (271) Show / Hide
Range on Protein: 28-295
Range on HMM: 3-270/271
Sequence Identity: 50% (134 aa)

EEEIRYLTVQATEIFINQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPQSNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASIN
.|||  .  .| .||...  | |.|||||. ||.|.|. || |||.  | .|.  ..|||||||||.|..|.. ||...||.|... ..|||||| ||.|
keeiisvireaeaifsdekalveieapikvvgdlhaqfqdlirlfdllgrvpeeklvflgdyvdrgpqgievlillfclkiryrdrivllrgnheiasvn

RIYGFYDECKRRYNSKLWKAFTDCFNCLPVAAIIDEKIFCMHGGLSPDLKNMDQIRRITRPTVVPDFGLLCDLLWADPDKNIQGWEDNDRGVSYTFGADV
..||||.||. .|  .||  |  ||| ||..|.| .|..||||||||.| ..|..| | .|.| ||| ||||||||.. ..|    ||.||||| .||| 
kkygfyeecvtkygeelwadfqrcfnrlpisaliakkvlcmhgglspelisldelrnipkpienldrgllidllwadpdnkveewkasirgisytfgkgv

VESFLKKHDLDLVCRAHQVVEDGYEFFAKRQLVTLFSAPNYFGEFDNAGAMMGVDETLMCSFQILKPA
  |. ..||. |||||| |||| .. |.|.|.||.|||   |||.|.. .||.|  |.. | |.    
vedvckslevdliirahqvvqdgyevlsgrklitvfsvpnycaqfknaaavlkldenleislvalvpe

Phosphatase pppB.AA Subfamily.PPP4C.PD 27-293 49 2.9e-100 324.9 In-house 2-268 (271) Show / Hide
Range on Protein: 27-293
Range on HMM: 2-268/271
Sequence Identity: 49% (131 aa)

AEEEIRYLTVQATEIFINQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPQSNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASI
.|||.. |  .| ||....  . ....|. .|||||||.||||.||. ||  |. |||||||.||||. |.||. ||||.|..||..  ..|||||. .|
keeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesrqi

NRIYGFYDECKRRYNS-KLWKAFTDCFNCLPVAAIIDEKIFCMHGGLSPDLKNMDQIRRITRPTVVPDFGLLCDLLWADPDkNIQGWEDNDRGVSYTFGA
 ..||||||| |.| | ..|.  |. |. |..|||||.||||.||||||.....|.|| | | . ||. | ||||||.||....||    ||  | ||.|
tqvygfydeclrkygsaevwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpe-daegwavsprgagylfgs

DVVESFLKKHDLDLVCRAHQVVEDGYEFFAKRQLVTLFSAPNYFGEFDNAGAMMGVDETLMCSFQILK
||| | .. |..|.|||||.| .||..  .....|..|||||     |  |.. .||.|   |.|.. 
dvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkife

Phosphatase pppB.AA Subfamily.PPP2C.PD 26-295 50 1.4e-97 316.1 In-house 1-270 (271) Show / Hide
Range on Protein: 26-295
Range on HMM: 1-270/271
Sequence Identity: 50% (135 aa)

LAEEEIRYLTVQATEIFINQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPQSNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECAS
| |||.. |. .| ||. ..  . |...|. .|||.|||..||| ||  ||  |..||||.|||||||  |.||..||.| |..|.|   |||||||   
leeeevkklcekakeilskesnvkevkcpvtvcgdvhgqfhdllelfriggkspdtnylfmgdyvdrgyysvetvtllvalkvrykeritilrgnhesrq

INRIYGFYDECKRRY-NSKLWKAFTDCFNCLPVAAIIDEKIFCMHGGLSPDLKNMDQIRRITRPTVVPDFGLLCDLLWADPDKNiQGWEDNDRGVSYTFG
| ..||||||| |.| |...|| ||| |..||..|..|..|||.|||||| .. .|.|| . |   ||  | .|||||.|||.||.   ||  |||| |.
itqvygfydeclrkygnanvwkyftdlfdylpltalvdnqifclhgglspsidtldkiraldrlqevphegpmcdllwsdpddr-ggwgisprgagytfg

ADVVESFLKKHDLDLVCRAHQVVEDGYEFFAKRQLVTLFSAPNYFGEFDNAGAMMGVDETLMCSFQILKPA
 |.| |. .| ||.||||.| .||..  .|..||.||||||     | .|.. .|..|  ||   .||   
kdiseefnktngltlvsrahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddelkysflqfdpa

Phosphatase pppB.AA Subfamily.PPP_Nematode_3.PD 80-295 53 1.4e-97 316.4 In-house 92-307 (308) Show / Hide
Range on Protein: 80-295
Range on HMM: 92-307/308
Sequence Identity: 53% (115 aa)

QSNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNSKLWKAFTDCFNCLPVAAIIDEKIFCMHGGLSPDLKNM
...|||||||||||  |.| . ||.|.|..||.. |.||||||  ..|. |||| |.|.||...|..||   ||.||..|....||.|||||.| .| ..
ykkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysaalyeafqlafnvlplcavvnkkilcmhGGiseelldl

DQIRRITRPTVVPDFGLLCDLLWADPDKNIQGWEDNDRGVSYTFGADVVESFLKKHDLDLVCRAHQVVEDGYEFFAKRQLVTLFSAPNYFGEFDNAGAMM
.|. .. ||. .|| |.|.|| |||||....|...  || .  |||. |. ||||.||||| |||||||||||||| |.|||.||||.| |..||..|..
kqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavl

GVDETLMCSFQILKPA
 ||. |..|...|.| 
svdkklvisltvlrpe

Phosphatase pppB.AA Subfamily.PPP_Nematode_5.PD 31-295 48 3.1e-97 314.7 In-house 6-273 (274) Show / Hide
Range on Protein: 31-295
Range on HMM: 6-273/274
Sequence Identity: 48% (127 aa)

IRYLTVQATEIFINQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPQSNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIY
|  .  .....    . |||.||||.|.||||||. ||||.|.  | .|. .||||||||||| .||| . ||...||.||..  .||||||.  ||..|
ilevlekikstlkplaalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrgnhevkkinkly

GFYDECKRRYNSKLWKAFTDCFNCLPVAAIIDEKIFCMHGGLSPDLKNMDQIRRITRPTVVPDF--GLLCDLLWADPDKNIQGWEDND-RGVSYTFGADV
||..| |......|.| | | |. ||. |.....|.|||||.||.|| .|... ...||.  .||  |||||||.|. .. | |  |..|  ||  .|..
gfkeelkkkrqeslykkfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkiraisvvfGkke

VESFLKKHDLDLVCRAHQVVEDGYEFFAKRQLVTLFSAPNYFGEFDNAGAMMGVDETLMCSFQILKPA
.||| |.||. |||.|.|.||.|.....|||.|||| | ||| ||.. |...|  ||  |||      
vddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkpe

Phosphatase pppB.AA Subfamily.PPP6C.PD 26-290 43 2.6e-91 295.4 In-house 1-265 (271) Show / Hide
Range on Protein: 26-290
Range on HMM: 1-265/271
Sequence Identity: 43% (116 aa)

LAEEEIRYLTVQATEIFINQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPQSNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECAS
|.|.|.. |  . .......  .  ...|. .|||||||.|||. ||  ||  |...|.||||.||||  ||||. .||. |.|||..  .||||||.  
lpenelkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesrq

INRIYGFYDECKRRY-NSKLWKAFTDCFNCLPVAAIIDEKIFCMHGGLSPDLKNMDQIRRITRPTVVPDFGLLCDLLWADPDkNIQGWEDNDRGVSYTFG
| ..|||||||...| |.. || .|. |. |..||||||...|.|||||||.| .|||| |.| . .|  | .|||.|.||.... |.  .||  | ||.
itqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhgglspdvktldqirvieraqeiphkgafcdlvwsdpe-dvetwavsprgagylfg

ADVVESFLKKHDLDLVCRAHQVVEDGYEFFAKRQLVTLFSAPNYFGEFDNAGAMMGVDETLMCSFQ
 |...|..  .|.|.|||||.||.|.... . .|||..|||||     |  ... ....   ... 
skvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgniasilaledaeereak

Phosphatase pppB.AA Subfamily.PPP_Nematode_2.PD 27-293 45 5.6e-91 294.2 In-house 2-278 (281) Show / Hide
Range on Protein: 27-293
Range on HMM: 2-278/281
Sequence Identity: 45% (126 aa)

AEEEIRYLTVQATEIFINQPILLELEA---PIKICGDIHGQYYDLLRLFEYGGFPPQSNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHEC
..|||| ..  |.. | ... ||...    |... .|.|||. ||||.|   . |..|.|||||||||||.||.|...|||||| .||.  |.|||||| 
skeeiriisnyakkaflefsallrvdeeclpvtvvadlhgqsidllriflineapgiskylflgdyvdrgrqsvevvllllaykhlypdhlfllrgnhed

ASINRIYGFYDECKRRYNS---KLWKAFTDCFNCLPVAAIIDEKIFCMHGGLSPDLKNMDQIRRITRPTVVPDFGLLCDLLWADPDKN-IQGWEDNDRGV
      |||.|||. .||    | |. . |.||.||.||.| .|..|.|||.|| |.....| .| ||.||| .|| |||||.||.|   .||    ||.
vnttltygffdeclekyndkgekvwlmiidafnhlplaalildkvlcahggisphlekledidkierplvvpsyglacdllwsdpektervgwslsargi

SYTFGADVVESFLKKHDLDLVCRAHQVVE----DGYEFFAKRQLVTLFSAPNYFGEfDNAGAMMGVDETLMCSFQILK
|..|.  ||| | .. ||||| ||||...    .|. . |. .||.|||| || .  .|  ... ..|     |  ||
sfsfddivvekfcadndldlvvrahqlskemirqghklrangrlvslfsalnylsm-kndssvlkleevktlqfvklk

Phosphatase pppB.AA Subfamily.PPP3C.PD 28-286 42 1.4e-86 280.2 In-house 3-274 (292) Show / Hide
Range on Protein: 28-286
Range on HMM: 3-274/292
Sequence Identity: 42% (112 aa)

EEEIRYLTVQATEIFINQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPQSNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASIN
||..  .  .|.... ... |||.|||| ..||||||.||||.||| || | ...|||||||||||  |.|..  |.| ||.||...|.|||||||  . 
eesalkiieeaakllkkeetlleveapitviGdihGqfydllklfevgGkpastkylflGdyvdrGyfsiecvlylyalkiaypsrlfllrGnhecrhlt

RIYGFYDECKRRYNSKLWKAFTDCFNCLPVAAIIDEKIFCMHGGLSPDLKNMDQIRRITRPTVVPDFGLLCDLLWADPDKNI------QGWED-NDRGVS
  . | .|.| .|. ....|....|..||.||....| .|.||||||..|..|.|... |   .| .| ||||||.|| ... .   . || || ..   
eyftfkeevkikyseevyealmesfdslplaallnqkflcvhGGlspeikslddikkldrfkeppasGplcdllwsdpledygeeetseeflpnsvrGcs

YTFGADVVESFLKKHDLDLVCRAHQVVEDGYEFFAK------RQLVTLFSAPNYFGEFDNAGAMMGVDETLM
| .||.| ||  . |||.. ..||. . |        |.|||||||| . ..| .|.. ...  .       
yfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfpslitlfsapnyldvynnkaavlkyennvl

Phosphatase pppB.AA Subfamily.PPP5C.PD 34-284 44 1.7e-83 270.3 In-house 78-334 (346) Show / Hide
Range on Protein: 34-284
Range on HMM: 78-334/346
Sequence Identity: 44% (114 aa)

LTVQATEIFINQPILLELEAP----IKICGDIHGQYYDLLRLFEYGGFPPQS-NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINR
. ..|.|.. ..| |.|.. |    | .|||||||.|||| .||  | | ..  ||| ||.||||  |.|.| .||..|. ||..||. |||||  ..|.
illeakellkklpslveitipetkkitvCgdihgqfyDllnifelnGlpseenpylfngDfvdrGsfsveviltllgfkllypnhfflsrGnhesdnmnk

IYGFYDECKRRYNSKLWKAFTDCFNCLPVAAIIDEKIFCMHGGL-SPDLKNMDQIRRITRPTVVPDFGLLCDLLWADPDKNiQGWEDNDRGVSYTFGADV
.||| .|.| .|..|. . ||. || ||.| .|.||.. .|||| | |   .|..|.| | .  |. |||..|||.||....|     |||. .|| || 
lyGfegevkakytekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeeglllellwsdpqea-nGrspskrGvgiqfGpdv

VESFLKKHDLDLVCRAHQVVEDGYEFFAKRQLVTLFSAPNYFGEFDNAGAMMGV-DET
. |||. .|.|. |.|.| |.|||.  . .|.|.||||||  . .| ||.. . ..  
tkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgdd

Phosphatase pppB.AA Subfamily.PPP_Nematode_7.PD 29-293 37 6.2e-72 232.0 In-house 4-293 (296) Show / Hide
Range on Protein: 29-293
Range on HMM: 4-293/296
Sequence Identity: 37% (108 aa)

EEIRYLTVQATEIFINQPILLELEAPIKICGDIHGQYYDLLRLF----------EYGGFP-PQSNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFIL
.|.  |  ...| | .. .|.|. .|. | ||||||| || |.           .  ...  .. ..|||||||||..|.||.|..|.|| ||.....||
nellslidavkelfkkektlaeispPvtivGdihGqyeDLvriLnarvskeeakqksalsfvrkkfvfLGdYvdrGsksieCisLvfalkilyptkyill

RGNHECASINRIYGFYDECKRR----YNSKLWKAFTDCFNCLPVAAIIDEKIFCMHGGLSPDLKNMDQIRRITRPTVVP-DFGLLCDLLWADP-------
||||. .||  |.|  | . |       .... | ..|  .|.||.. |||.|.|||.|| |....|..|.|| .   .  |  |||.|||         
rGnhetkainfayefreelenrlskidgkeiyekfnevfsfmplaalvgekilcvhggispklesledinsierPlaevtedslakdllfadpldvqlla

-DKNIQGWEDN-DRGVSYTFGADVVESFLKKHDLDLVCRAHQVVEDGYEFFAKRQLVTLFSAPNYFGEFDNAGAMMGVDETLMCSFQILK
..   .| |  ||.|..|.   || . .| .|.|. |||| .|..|||...|.|.||||.| .|.|| ||.. |.     | ..|.    
avsekpkyeknevrglsvvfneaavedvCrklnlklivrahqkipegfkffadkkLltifsaprymnesdnsgavlkveangklsiaslr

Phosphatase pppB.AA Subfamily.PPP_Nematode_1.PD 43-293 29 7.4e-47 149.8 In-house 17-268 (273) Show / Hide
Range on Protein: 43-293
Range on HMM: 17-268/273
Sequence Identity: 29% (74 aa)

INQPILLE-LEAPIKICGDIHGQYYDLLRLFEYGGFPPQSNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECK-RRY
.... ||| .||.....||| ..| |||....  |.|..  .||||. .| || |||.. .||  |. ||.|..||||..|.     .. | . |  .|.
aeetslleyieadvtviGdirsryadlldilkltGwPfeqkilflGnlldsGkssleellillcskkcyPknvvilrGeyetelvksdrrligelrvrfp

NSKLWKAFTDCFN----CLPVAAIIDEKIFCMHGGLSPDLKNMDQIRRITRPTVVPDFGLLCDLLWADPDKNIQGWEDNdrgvsyTFGA-DVVESFLKKH
 |.|   .       |||||... |......|.|. .|. ...  . |  .  .     ... | |.     |..       ..   .|   ||  |...
dsnkwralnaiikrllkrlPvaavlnkkllavysgvssnikekknvvavkrgiifenhstrvevqfldidiPsPvtend------idekskivkellkat

DLDLVCRAHQVVEDGYEFFAKRQLVTLFSAPNYFGEFDNAGAMMGVDETLMCSFQILK
. |...|| .|| |  | .|.||.||...  ...| |... .|  |  .|. ..    
dmsvmirsnsvvreGylftlknrlitltsatklqkdynnrGvvlsidkdlkvtfklie

Phosphatase pppB.AA Metallophos 53-248 30 3.4e-45 161.27 Pfam 1-124 (124) Show / Hide
Range on Protein: 53-248
Range on HMM: 1-124/124
Sequence Identity: 30% (60 aa)

APIKICGDIHGQYYDLLRLFEYGGFPPQSNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNSKLWKAFTDCF
..| .||||||||.||.|||| .   .  ...|.|||||||..|.|.|.||..||..|| .....||||.....|. |||| |       ..| .. ..|
MRILHCGDIHGQYDDLNRLFEII-E-KPDFVIFTGDYVDRGPWSDECIWLLFCYKMNYPGPVYWVRGNHDYMHGNDFYGFY-E-------NDW-MWWWWF

NCLPVAAIIDEKIFCMHGGLSPDLKNMDQIRRITRPTVVPDFGLLCDLLWADPDKNIQGWEDNDRGVSYTFGADVVESFLKKHDLDLVCRAHQVVE
 ..| | ..| ||.||||..                                                          |.| ...|.|.|.|. |.
-WMPLA-LDDWKILCMHGPP----------------------------------------------------------FCK-NGVDYVIRGHTHVP

Phosphatase pppB.AA Subfamily.PPP7C.PD 53-188 40 1.1e-39 125.9 In-house 68-206 (338) Show / Hide
Range on Protein: 53-188
Range on HMM: 68-206/338
Sequence Identity: 40% (54 aa)

APIKICGDIHGQYYDLLRLFEYGGFPPQS-NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRY---NSKLWKAF
...|||.||.  ||| ..   |.| .. .|.| ||.|||||.|.| ...|.|. . ||..... |||||   .|  |||  | . .|..|. . . | | 
kevtvcgdlhgklddlllilyknGlpsaenpyvfnGdfvdrGkesveillilfalllvypkevylnrGnhedyilnlryGfikeveskykvhgkkilrll

TDCFNCLPVAAIIDEKIFCMHGGLSpDLKNMDQIRRITRP
 ||.|..|||||. .|||.| |  ... . .| |      
edvfawlplatlidekilivhGGis-dktdlelldkiers

Phosphatase pppB.AA Subfamily.PPP7C.PD 196-286 35 3.5e-22 68.4 In-house 238-328 (338) Show / Hide
Range on Protein: 196-286
Range on HMM: 238-328/338
Sequence Identity: 35% (32 aa)

LLCDLLWADPDKNIQGWEDNDRGVSYTFGADVVESFLKKHDLDLVCRAHQVVEDGYEFFAKRQLVTLFSAPNYFGEFDNAGAMMGVDETLM
. |.||.|| ..   . .  ||    ||.|| ...|.|..|.|. |.|.   .||||  .....|.||| ||. |  | || . . ..|. 
qildilwsdpkaqeGckpntlrGgGsyfGpdvtkkllqkynlellirsheckpeGyefthnkkvltifsasnyyeeGsnrGayvklgkdlt

Phosphatase pppB.AA Subfamily.PPP_Nematode_3.PD 27-80 50 6.6e-16 48.3 In-house 2-55 (308) Show / Hide
Range on Protein: 27-80
Range on HMM: 2-55/308
Sequence Identity: 50% (26 aa)

AEEEIRYLTVQATEIFINQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPQ
|.|.  |  .| |.| ..|. ||||||..|.||||||. ||| |..  |.|   
kekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnGwpls

Sequence
Name Sequence Type Origin Length Description Download
pppB.AA Protein None 321 None Fasta, JSON
pppB.NA RNA None 966 None Fasta, JSON
pppB.AA.PD_26-296 Protein Phosphatase Domain None 271 None Fasta, JSON