ppp4C
Species: D.discoideum
Alias: ppp4C, DDB_G0272116
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: PPP
Family: PPP
Subfamily: PPP4C
Protein domain

Protein domains of ppp4C.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase ppp4C.AA Subfamily.PPP7C.PD 3-182 35 1.8e-37 118.7 In-house 22-207 (338) Show / Hide
Range on Protein: 3-182
Range on HMM: 22-207/338
Sequence Identity: 35% (65 aa)

SDLDRQIEQLKRCEIIKESEVRALCSKAREILLEEGNVQRVDS----PVTICGDIHGQFYDLKE-LFKVGGDCPQTNYLFMGDFVDRGFYSVETFLLLLA
.|... .|..|  ....   |  .  .....| .  |..|| .     ||.|||.||.. ||   |.| |   .. .|.| |||||||  |||  |.|.|
ddveklleafklkkllhakyvllilretkkvlkqlpnisrvstaiskevtvcgdlhgklddlllilyknGlpsaenpyvfnGdfvdrGkesveillilfa

LKVRYPDRITLIRGNHESRQITQVYGFYEECVRKY--GSVTVWKYCTEIFDYLSLSALVDGKIFCVHGGLSPSiNTLDQIRAIDRKQ
| . ||  . | |||||   .   |||  |   ||   .  . .   ..| .| |..|.| ||. ||||.| .   |. .|.|..  
lllvypkevylnrGnhedyilnlryGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGisdk-tdlelldkiersk

Phosphatase ppp4C.AA Subfamily.PPP4C.PD 18-288 81 1.2e-170 555.7 In-house 1-271 (271) Show / Hide
Range on Protein: 18-288
Range on HMM: 1-271/271
Sequence Identity: 81% (222 aa)

IKESEVRALCSKAREILLEEGNVQRVDSPVTICGDIHGQFYDLKELFKVGGDCPQTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQ
|||.||.|||.||||||.||.||||||||||.|||||||||||.||||||||.|.|||||.|||||||||||||||||||||||||||||||||||||||
ikeeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesrq

ITQVYGFYEECVRKYGSVTVWKYCTEIFDYLSLSALVDGKIFCVHGGLSPSINTLDQIRAIDRKQEVPHEGPMCDLMWSDPEDIPGWNGSPRGAGFLFGE
||||||||.||.|||||..||.||||.||||||.|..|||||||||||||||.|||.||.||||||||||||.|||.||||||. ||. ||||||.|||.
itqvygfydeclrkygsaevwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpedaegwavsprgagylfgs

DVVQKFNHDNNLEFICRAHQLVMEGFKYMFNETLVTVWSAPNYCYRCGNVAAILQLDENLKKNFAIFEAAP
|||..||..|..|.|||||||||||.|..|||...|||||||||||||||||||.|||.|.|.|.|||||.
dvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkifeaaa

Phosphatase ppp4C.AA PP2Ac 18-288 42 7.29999999999e-151 508.41 SMART 1-321 (321) Show / Hide
Range on Protein: 18-288
Range on HMM: 1-321/321
Sequence Identity: 42% (135 aa)

IKESEVRALCSKAREILLEEGNVQRVD----SPVTICGDIHGQFYDLKELF---KVGG-DCPQTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLI
. ..|...||....||.  | |. .|.    .|||.||||||||.|| .||   ...|  .|.|||.|.||.||||..|.|. .||...|..||....| 
MHKHEIYQLCHEVKEIFRQEPNMVEVEETPTPPVTVCGDIHGQFDDLLRLFKKEDKNGKPPPYTNYVFLGDYVDRGPWSIECICLLFCYKICYPNNFFLL

RGNHESRQIT---QVYGFYEECVRKYGSVTVWKYCTEIFDYLSLSALVDGKIFCVHGGLSP------SINTLDQIRAIDR----KQEVPHEGPMCDLMWS
|||||.|...   |.||||.|| |||... .||...| |....|.||...||.|.||||||      .|.|||.|| |||     || |..|.||||.||
RGNHECRHMNMWVQYYGFYDECKRKYYHKRIWKIFQECFSWMPLCALINNKILCMHGGLSPRECQTDHIHTLDDIRNIDRPQHPPQEPPDWGLMCDLLWS

DP---------EDIPGWNGSP-RGAGFLFGEDVVQKFNHDNNLEFICRAHQLVM----EGFKYMFNE-----TLVTVWSAPNYCYRCGNVAAILQL----
||          . |||  .. ||... ||.||| .| . |||. |.||||.|.    .|.......      |.|..||||||..|.| ||....    
DPVDFQWFHDDQWVPGWQPNCMRGMSYYFGPDVVDEFCKKNNLDLIIRAHQCVQYQMMDGYEFWHDRDTRVHKLITIFSAPNYCDQCDNHAAVMKVNDHK

------DENLKKNFAIFEAAP
      |.||| .|  |....
VIQYKMDKNLKCHFVQFKPQM

Phosphatase ppp4C.AA Subfamily.PPP6C.PD 19-288 64 1.9e-147 479.6 In-house 2-271 (271) Show / Hide
Range on Protein: 19-288
Range on HMM: 2-271/271
Sequence Identity: 64% (174 aa)

KESEVRALCSKAREILLEEGNVQRVDSPVTICGDIHGQFYDLKELFKVGGDCPQTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQI
.|.|...||..  ..||||.||| | ||||.|||||||||||.|||. ||. |.|.|.|.|||||||.||.||| .||.||..|||||||.|||||||||
penelkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesrqi

TQVYGFYEECVRKYGSVTVWKYCTEIFDYLSLSALVDGKIFCVHGGLSPSINTLDQIRAIDRKQEVPHEGPMCDLMWSDPEDIPGWNGSPRGAGFLFGED
|||||||.||..|||....|||||..|| |...|..|....|||||||| ..|||||| |.| ||.||.|..|||.||||||.  |. ||||||.|||. 
tqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhgglspdvktldqirvieraqeiphkgafcdlvwsdpedvetwavsprgagylfgsk

VVQKFNHDNNLEFICRAHQLVMEGFKYMFNETLVTVWSAPNYCYRCGNVAAILQLDENLKKNFAIFEAAP
|...|.| |||..||||||||.||.||||.| ||||||||||||||||.|.||.|... .... .|.| |
vtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgniasilaledaeereaklfkavp

Phosphatase ppp4C.AA Subfamily.PPP2C.PD 19-288 67 2.2e-145 472.9 In-house 2-271 (271) Show / Hide
Range on Protein: 19-288
Range on HMM: 2-271/271
Sequence Identity: 67% (181 aa)

KESEVRALCSKAREILLEEGNVQRVDSPVTICGDIHGQFYDLKELFKVGGDCPQTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQI
.|.||..|| ||.||| .| ||. |  |||.|||.||||.|| |||..||..|.||||||||.||||.|||||  ||.||||||..|||..|||||||||
eeeevkklcekakeilskesnvkevkcpvtvcgdvhgqfhdllelfriggkspdtnylfmgdyvdrgyysvetvtllvalkvrykeritilrgnhesrqi

TQVYGFYEECVRKYGSVTVWKYCTEIFDYLSLSALVDGKIFCVHGGLSPSINTLDQIRAIDRKQEVPHEGPMCDLMWSDPEDIPGWNGSPRGAGFLFGED
|||||||.||.||||. .|||| |..|||| |.||||..|||.||||||||.|||.|||.|| ||||||||||||.||||.|||. ||||||. ||.|. 
tqvygfydeclrkygnanvwkyftdlfdylpltalvdnqifclhgglspsidtldkiraldrlqevphegpmcdllwsdpddrggwgisprgagytfgkd

VVQKFNHDNNLEFICRAHQLVMEGFKYMFNETLVTVWSAPNYCYRCGNVAAILQLDENLKKNFAIFEAAP
..||. |.|....|||||||||...  .. .||..||||||||||| ||||.||..||..|  |. ||  
iseefnktngltlvsrahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddelkysflqfdpap

Phosphatase ppp4C.AA Family.PPP.PD 6-291 49 9.3e-131 426.1 In-house 56-343 (349) Show / Hide
Range on Protein: 6-291
Range on HMM: 56-343/349
Sequence Identity: 49% (142 aa)

DRQIEQLKRCEIIKESEVRALCSKAREILLEEGNVQRVDSPVTICGDIHGQFYDLKELFKVGGDCPQT-NYLFMGDFVDRGFYSVETFLLLLALKVRYPD
.. .|..|. . ....|| .|...|.|.| .| |...|..|.|.||||||||.|| .||...| .|.. .|||.||.|||| .|||..|||.|||..||.
kelveafkekkqleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllyps

RITLIRGNHESRQITQVYGFYEECVRKYGS-VTVWKYCTEIFDYLSLSALVDGKIFCVHGGLSPSINTLDQIRAIDRKQEVPHEGPMCDLMWSDPEDIPG
|..|.|||||||....|||||||. .|| .  .......|.|..|.|.||.|.||.||||||||....|||||.|.|..|.|.||..|||.|||||. .|
rffllRGnhEsrsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdpeeqkg

WNGSPRGAGFLFGEDVVQKFNHDNNLEFICRAHQLVMEGFKYMFNETLVTVWSAPNYCYRCGNVAAILQLDENLKKNFAIFEAAPQES
|. ..||.||.||.|.|.|| . |||..|.|||..|.||.....|. |||..||||||....| ||.|..|.||| .. .|...... 
wkpnkRGvgfvFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskhkl

Phosphatase ppp4C.AA Group.PPP.PD 6-291 49 9.3e-131 426.1 In-house 56-343 (349) Show / Hide
Range on Protein: 6-291
Range on HMM: 56-343/349
Sequence Identity: 49% (142 aa)

DRQIEQLKRCEIIKESEVRALCSKAREILLEEGNVQRVDSPVTICGDIHGQFYDLKELFKVGGDCPQT-NYLFMGDFVDRGFYSVETFLLLLALKVRYPD
.. .|..|. . ....|| .|...|.|.| .| |...|..|.|.||||||||.|| .||...| .|.. .|||.||.|||| .|||..|||.|||..||.
kelveafkekkqleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllyps

RITLIRGNHESRQITQVYGFYEECVRKYGS-VTVWKYCTEIFDYLSLSALVDGKIFCVHGGLSPSINTLDQIRAIDRKQEVPHEGPMCDLMWSDPEDIPG
|..|.|||||||....|||||||. .|| .  .......|.|..|.|.||.|.||.||||||||....|||||.|.|..|.|.||..|||.|||||. .|
rffllRGnhEsrsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdpeeqkg

WNGSPRGAGFLFGEDVVQKFNHDNNLEFICRAHQLVMEGFKYMFNETLVTVWSAPNYCYRCGNVAAILQLDENLKKNFAIFEAAPQES
|. ..||.||.||.|.|.|| . |||..|.|||..|.||.....|. |||..||||||....| ||.|..|.||| .. .|...... 
wkpnkRGvgfvFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskhkl

Phosphatase ppp4C.AA Subfamily.PPP1C.PD 18-286 49 1.8e-102 332.4 In-house 1-269 (271) Show / Hide
Range on Protein: 18-286
Range on HMM: 1-269/271
Sequence Identity: 49% (132 aa)

IKESEVRALCSKAREILLEEGNVQRVDSPVTICGDIHGQFYDLKELFKVGGDCPQTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQ
.||.|.|.||.|||||.|..  . ....|. |.||||||..||  ||. ||  |..||||.||.||||  |.|| .||||.|..||... |.|||||. .
lkeaeirklclkareiflsqpilleleaplkivGdihGqyadllrlfekggfppesnylflGdyvdrGkqsletivlllaykikypenffllrGnhecas

ITQVYGFYEECVRKYgSVTVWKYCTEIFDYLSLSALVDGKIFCVHGGLSPSINTLDQIRAIDRKQEVPHEGPMCDLMWSDPE-DIPGWNGSPRGAGFLFG
|...||||.|| |.| .. .||  ...|. | ..|.|| |||||||||||....|.||| | |  .||..| .|||.||||... ||. . ||  | ||.
inriygfydeckrry-niklwktfvdcfnclpvaaivdekifcvhGGlspdlksleqirriarptdvpdkGllcdllwsdpdkevkgwgendrgvsftfg

EDVVQKFNHDNNLEFICRAHQLVMEGFKYMFNETLVTVWSAPNYCYRCGNVAAILQLDENLKKNFAIFEA
|||.|| . ..|..|.||||.| .|.... .  |||..|||||| .  |..|....||.|  .| |... 
advvekflkkhdldlivrahqvvedgyeffakrqlvtlfsapnycgefdnagavmsvdeellcsfqilkp

Phosphatase ppp4C.AA Subfamily.PPP_Nematode_6.PD 18-285 43 1e-93 303.3 In-house 1-269 (272) Show / Hide
Range on Protein: 18-285
Range on HMM: 1-269/272
Sequence Identity: 43% (117 aa)

IKESEVRALCSKAREILLEEGNVQRVDSPVTICGDIHGQFYDLKELFKVGGDCPQTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQ
|||.|.  |...|.... ..  .  |..|...|||||||. ||  ||. ||  |..||||.||.|||| .|.|. ||||| ||..|... |.|||||  .
ikeeellkllelakkvfkkqkslveveapikvcGdihGqysdllrlfdkggfppdanylflGdyvdrGrqslevillllaykvkfpnnffllrGnhecea

ITQVYGFYEECVRKYGSVTVWKYCTEIFDYLSLSALVDGKIFCVHGGLSPSINTLDQIRAIDRKQEVPHEGPMCDLMWSDPED-IPGWNGSPRGAGFLFG
| .|||||.|. |.| |.....   |.|..| |.||| |.|.|.|||||.....|||.|.. |.. ..|    ||.|||||. . ||. . ||..  |||
inrvyGfydevqrrykstrlyaafqevfnalpltalvsgrilcmhGGlskklksldqlrelkrpldskeeslaidllwsdpenavkgwaensrGvsvvfG

EDVVQKFNHDNNLEFICRAHQLVMEGFKYMFNETLVTVWSAPNYCYRCGNVAAILQLDENLKKNFAIFE
|.|.|. .. ......||||.| .|.... .  |||..|||.||.  | ||....||.|.  | ...  
edavkkllekldidlvarahqvvqdGyeffaekklvtifsaphycgqfdnaaavmkvdeklvvsfevlk

Phosphatase ppp4C.AA Subfamily.PPP_Nematode_4.PD 21-282 41 3.4e-84 272.2 In-house 4-265 (271) Show / Hide
Range on Protein: 21-282
Range on HMM: 4-265/271
Sequence Identity: 41% (107 aa)

SEVRALCSKAREILLEEGNVQRVDSPVTICGDIHGQFYDLKELFKVGGDCPQTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQ
|. ..  .|..|. .| ..  ...|. . ||.|.|| ||..||.. |  |.. ..|.||.||||  ..|...||..||.||.||| |.|||||  .. ..
eeiisvireaeaifsdekalveieapikvvgdlhaqfqdlirlfdllgrvpeeklvflgdyvdrgpqgievlillfclkiryrdrivllrgnheiasvnk

VYGFYEECVRKYGsVTVWKYCTEIFDYLSLSALVDGKIFCVHGGLSPSINTLDQIRAIDRKQEVPHEGPMCDLMWSDPED-IPGWNGSPRGAGFLFGEDV
|||||||| ||| . .|    . |. | .|||.  |..|.||||||.. .||..| | .  |.. | . ||.|.||..   .|  | ||....||..||.
kygfyeecvtkyg-eelwadfqrcfnrlpisaliakkvlcmhgglspelisldelrnipkpienldrgllidllwadpdnkveewkasirgisytfgkgv

VQKFNHDNNLEFICRAHQLVMEGFKYMFNETLVTVWSAPNYCYRCGNVAAILQLDENLKKNFA
.  .  ....| ||||.|..|.. .    |.||.|.||||| ||.|.|||||. ..       
vedvckslevdliirahqvvqdgyevlsgrklitvfsvpnycaqfknaaavlkldenleislv

Phosphatase ppp4C.AA Subfamily.PPP5C.PD 22-287 42 4.1e-84 272.2 In-house 74-345 (346) Show / Hide
Range on Protein: 22-287
Range on HMM: 74-345/346
Sequence Identity: 42% (115 aa)

EVRALCSKAREILLEEGNVQRVD----SPVTICGDIHGQFYDLKELFKVGGDCP-QTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESR
. .. ..| |.| ..  .  ..    . .|.||||||||||| ..|.. |    .  ||| ||||||| .|||. |.||..|. ||...| |||||| ..
yalkilleakellkklpslveitipetkkitvCgdihgqfyDllnifelnGlpseenpylfngDfvdrGsfsveviltllgfkllypnhfflsrGnhesd

QITQVYGFYEECVRKYGSvTVWKYCTEIFDYLSLSALVDGKIFCVHGGLSP-SINTLDQIRAIDRKQEVPHEGPMCDLMWSDPEDIPGWNGSPRGAGFLF
 ..||| .|.  || . .| .  ||.|..| |. ... |.. |||||      |||..| ||| .. |.||....|.||||.. .| . | || |. || 
nmnklyGfegevkakyte-kvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeeglllellwsdpqeanGrspskrGvgiqf

GEDVVQKFNHDNNLEFICRAHQLVMEGFKYMFNETLVTVWSAPNYCYRCGNVAAILQL-DENLKKNFAIFEAA
|| .|| ..|||| | |.|.. .||.. . .  |.||.|||||| . || .|...| ...|| .|  |||   
GpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlkpkfktfeav

Phosphatase ppp4C.AA Subfamily.PPP3C.PD 19-277 42 7.9e-83 267.9 In-house 2-273 (292) Show / Hide
Range on Protein: 19-277
Range on HMM: 2-273/292
Sequence Identity: 42% (114 aa)

KESEVRALCSKAREILLEEGNVQRVDSPVTICGDIHGQFYDLKELFKVGGDCPQTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQI
.|...  . ..| ..| .| .. .|..|.|..|||||||||| .||.|||.  .|.|||.||.|||| .|.|. | |.|||. ||.|. |.|||||.|..
eeesalkiieeaakllkkeetlleveapitviGdihGqfydllklfevgGkpastkylflGdyvdrGyfsiecvlylyalkiaypsrlfllrGnhecrhl

TQVYGFYEECVRKYGsVTVWKYCTEIFDYLSLSALVDGKIFCVHGGLSPSINTLDQIRAIDRKQEVPHEGPMCDLMWSDPEDIPG--------WNGSPRG
|. . | ||.  ||.  .|.. ..| || | |.||...| .|||||||| |..||.|...|| .|.|. ||.|||.|||| .|         . |.||  
teyftfkeevkikys-eevyealmesfdslplaallnqkflcvhGGlspeikslddikkldrfkeppasGplcdllwsdpledygeeetseeflpnsvrG

AGFLFGEDVVQKFNHDNNLEFICRAHQLVMEGFKYMFN------ETLVTVWSAPNYCYRCGNVAAILQLDENL
....   | .| ..|.|  | |||.   .|..   .       .|.|..|||||.    | ||.|....|   
csyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfpslitlfsapnyldvynnkaavlkyennv

Phosphatase ppp4C.AA Subfamily.PPP_Nematode_3.PD 72-285 40 1.7e-74 240.7 In-house 92-305 (308) Show / Hide
Range on Protein: 72-285
Range on HMM: 92-305/308
Sequence Identity: 40% (87 aa)

QTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYEECVRKYgSVTVWKYCTEIFDYLSLSALVDGKIFCVHGGLSPSINT
. .|||.||.|||| .|.|  .||.|||..|||...|.||||||| . . ||||.|. ..| |.....    .|  | |.|.|. ||.|.|||.| ..  
ykkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkry-saalyeafqlafnvlplcavvnkkilcmhGGiseelld

LDQIRAIDRKQEVPHEGPMCDLMWSDPE-DIPGWNGSPRGAGFLFGEDVVQKFNHDNNLEFICRAHQLVMEGFKYMFNETLVTVWSAPNYCYRCGNVAAI
|.|. ...|  ..|  | ..|| |.||. .. |.. |.||||..||.. |..|..  .|... ||||.|..|.... .  |||..|||.|| .  |.||.
lkqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaav

LQLDENLKKNFAIFE
|..|..|.  .... 
lsvdkklvisltvlr

Phosphatase ppp4C.AA Subfamily.PPP_Nematode_2.PD 21-277 43 1.9e-74 240.0 In-house 4-270 (281) Show / Hide
Range on Protein: 21-277
Range on HMM: 4-270/281
Sequence Identity: 43% (115 aa)

SEVRALCSKAREILLEEGNVQRVDS---PVTICGDIHGQFYDLKELFKVGGDCPQTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQ
|.| ... |.. .||   . |||    |||. .|.|||. ||. .| . .  ....|||.||.||||  |||. |||||.|.||| . |.|||||  . |
eeiriisnyakkaflefsallrvdeeclpvtvvadlhgqsidllriflineapgiskylflgdyvdrgrqsvevvllllaykhlypdhlfllrgnhedvn

ITQVYGFYEECVRKYGS--VTVWKYCTEIFDYLSLSALVDGKIFCVHGGLSPSINTLDQIRAIDRKQEVPHEGPMCDLMWSDPEDI--PGWNGSPRGAGF
  |||..||  ||.     ||..  . |..| |.||. .|..|.|||.|| .. |..|  |.|   ||  |  |||.|||||     ||. | ||  | |
ttltygffdeclekyndkgekvwlmiidafnhlplaalildkvlcahggisphlekledidkierplvvpsyglacdllwsdpektervgwslsargisf

LFGEDVVQKFNHDNNLEFICRAHQLVME----GFKYMFNETLVTVWSAPNYCYrCGNVAAILQLDENL
.. ||.|| .||.|... |||||. |    | |. .|  ||...|| ||    .| ...|.|.|    
sfddivvekfcadndldlvvrahqlskemirqghklrangrlvslfsalnyls-mkndssvlkleevk

Phosphatase ppp4C.AA Subfamily.PPP_Nematode_5.PD 21-283 37 3.6e-73 235.8 In-house 4-269 (274) Show / Hide
Range on Protein: 21-283
Range on HMM: 4-269/274
Sequence Identity: 37% (96 aa)

SEVRALCSKAREILLEEGNVQRVDSPVTICGDIHGQFYDLKELFKVGGDCPQTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQ
...  .  |....|     . .|..|.||.||||||. ||  .|.  |  |...|||.||.||||  |.|  |||..||..|| .. |.||||| ..| .
kdilevlekikstlkplaalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrgnhevkkink

VYGFYEECVRKYGsVTVWKYCTEIFDYLSLSALVDGKIFCVHGGLSPSINTLDQIRAIDRKQE--VPHEGPMCDLMWSDPE-DIPGWN-GSPRGAGFLFG
.|||.||  .|..  ...|   ..| .|.| | |. .|.|.|||.|| ...||...|. . ..|| . ||.|.||| |  . .    |.   .||. .| 
lygfkeelkkkrq-eslykkfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkiraisvvfG

EDVVQKFNHDNNLEFICRAHQLVMEGFKYMFNETLVTVWSAPNYCYRCGNVAAILQLDENLKKNFAI
.. .  ....| |||... ||....|.. ||||.||| |..  |..|...... |. .|        
kkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvv

Phosphatase ppp4C.AA Subfamily.PPP_Nematode_7.PD 20-284 34 2.1e-58 187.6 In-house 3-292 (296) Show / Hide
Range on Protein: 20-284
Range on HMM: 3-292/296
Sequence Identity: 34% (99 aa)

ESEVRALCSKAREILLEEGNVQRVDSPVTICGDIHGQFYDLKELF-----------KVGGDCPQTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITL
..|.  |. .. | . .| .. ..  |||| ||||||. ||  .            |..    .. ..|.||.|||| .|.||..|||. || .. |.||
knellslidavkelfkkektlaeispPvtivGdihGqyeDLvriLnarvskeeakqksalsfvrkkfvfLGdYvdrGsksieCisLvfalkilyptkyil

IRGNHESRQITQVYGFYEECVR---KYGSVTVWKYCTEIFDYLSLSALVDGKIFCVHGGLSPSINTLDQIRAIDRK-QEVPHEGPMCDLMWSDPED----
|||.. |   |.| || .    |  . ....   |.| .. |.|||  ||.|||||.|| ...|..|. |.|  .|| ..    ||...|| |       
lrGnhetkainfayefreelenrlskidgkeiyekfnevfsfmplaalvgekilcvhggispklesledinsierPlaevtedslakdllfadpldvqll

-----IPGWN-GSPRGAGFLFGEDVVQKFNHDNNLEFICRAHQLVMEGFKYMFNETLVTVWSAPNYCYRCGNVAAILQLDENLKKNFAIF
   | ..    ||  . |.|  |... . .||. | |||| .||||.. .. |.|..|||.|    .|  |.|... | | . |..    
aavsekpkyeknevrglsvvfneaavedvCrklnlklivrahqkipegfkffadkkLltifsaprymnesdnsgavlkveangklsiasl

Phosphatase ppp4C.AA Metallophos 45-240 25 9.2e-42 149.86 Pfam 1-124 (124) Show / Hide
Range on Protein: 45-240
Range on HMM: 1-124/124
Sequence Identity: 25% (49 aa)

SPVTICGDIHGQFYDLKELFKVGGDCPQTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYEECVRKYGSVTVWKYCTEI
 ....|||||||..||..||... . . ....|.||.|||| .| |...||...|..||... ..||||........|||| |        ..| .. ..
MRILHCGDIHGQYDDLNRLFEII-E-KPDFVIFTGDYVDRGPWSDECIWLLFCYKMNYPGPVYWVRGNHDYMHGNDFYGFY-E--------NDW-MWWWW

FDYLSLSALVDGKIFCVHGGLSPSINTLDQIRAIDRKQEVPHEGPMCDLMWSDPEDIPGWNGSPRGAGFLFGEDVVQKFNHDNNLEFICRAHQLVM
| .. |  |.|.||.|.||..                                                         |   |..  ..|.|. |.
F-WMPLA-LDDWKILCMHGPP---------------------------------------------------------FCK-NGVDYVIRGHTHVP

Phosphatase ppp4C.AA Subfamily.PPP_Nematode_1.PD 28-285 23 9.8e-36 113.3 In-house 11-268 (273) Show / Hide
Range on Protein: 28-285
Range on HMM: 11-268/273
Sequence Identity: 23% (61 aa)

SKAREILLEEGNVQRVDSPVTICGDIHGQFYDLKELFKVGGDCPQTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYEE
.| .|. |   .. ....||..||| ... ||....|. |  ..  .||.|...| | .|.|. |.||  |. || .. ..||..|   .     .. | 
edalkiaeetslleyieadvtviGdirsryadlldilkltGwPfeqkilflGnlldsGkssleellillcskkcyPknvvilrGeyetelvksdrrlige

CVRKYGSVTVWKYCTE----IFDYLSLSALVDGKIFCVHGGLSPSINTLDQIRAIDRKQEVPHEGPMCDLMWSDpEDIPgwngSPRGAGFLFGE-DVVQK
  ..     |.        .   | . |... |...|..|.|. |   ... |..|..   .... . |  |||    ||   . ....  .|..     
lrvrfpdsnkwralnaiikrllkrlPvaavlnkkllavysgvssnikekknvvavkrgiifenhstrvevqfld-idiP----sPvtendidekskivke

FNHDNNLEFICRAHQLVMEGFKYMFNETLVTVWSAPNYCYRCGNVAAILQLDENLKKNFAIFE
... . |....| ||... ... |.|..||...     |..| .| .|| .|  .|       
llkatdmsvmirsnsvvreGylftlknrlitltsatklqkdynnrGvvlsidkdlkvtfklie

Phosphatase ppp4C.AA Subfamily.PPP7C.PD 190-284 32 1e-19 60.4 In-house 239-334 (338) Show / Hide
Range on Protein: 190-284
Range on HMM: 239-334/338
Sequence Identity: 32% (31 aa)

MCDLMWSDPEDIPGW-NGSPRGAGFLFGEDVVQKFNHDNNLEFICRAHQLVMEGFKYMFNETLVTVWSAPNYCYRCGNVAAILQLDENLKKNFAIF
. |..||||.   |    . ||.|  || || .|. .  |||.. |.|.  .||.... |....|..|| ||     |  | ..| ..|...  . 
ildilwsdpkaqeGckpntlrGgGsyfGpdvtkkllqkynlellirsheckpeGyefthnkkvltifsasnyyeeGsnrGayvklgkdltprivqy

Phosphatase ppp4C.AA Subfamily.PPP_Nematode_3.PD 19-68 48 1.5e-13 40.5 In-house 2-51 (308) Show / Hide
Range on Protein: 19-68
Range on HMM: 2-51/308
Sequence Identity: 48% (24 aa)

KESEVRALCSKAREILLEEGNVQRVDSPVTICGDIHGQFYDLKELFKVGG
||.|.  || .|||.. .|    ....||||.||||||| ||. |... |
kekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnG

Sequence
Name Sequence Type Origin Length Description Download
ppp4C.AA Protein None 305 None Fasta, JSON
ppp4C.NA RNA None 918 None Fasta, JSON
ppp4C.AA.PD_18-288 Protein Phosphatase Domain None 271 None Fasta, JSON