Ptpmeg
Species: D.melanogaster
Alias: Ptpmeg
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: N3
Protein domain

Protein domains of Ptpmeg.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
FERM Ptpmeg.AA B41 30-232 28 7.9e-56 192.71 SMART 1-232 (232) Show / Hide
Range on Protein: 30-232
Range on HMM: 1-232/232
Sequence Identity: 28% (68 aa)

PQRQQCVTVLFLDDITHTFRIEKRAKGSELLDQVFQYLEL--SERDYFGLLFPQKPGDVVRWVDAQKQFKKQCSSVSLDNDAVPLLEFRVKFFVSD----
. .. .. |.|.|. | .|.......| .|.|.|.. ...  .|..|||| . .. .| ..| |  |  .||  ..   ... . | |||||...|    
SPKPRFCRVYFMDGTTLEFEVDSSTTGQDLCDHVCRHCGISPREHWYFGLWYEDPHED-RHWLDHWKTIMKQDVKW--HKSEPWTLHFRVKFYPPDWHGF

PSRLQEEFTRY-QFYLQIKRNILLGKLPCS-SNTQCLLASYTVQSELGDFNAL--------EHQPGYLSGMQLLCDQ---------------TTEAERKV
|..|||. ||| .||||....|| | .||.  ..  .||.. ||.|.||..          .| ..|.|  ..| .|               . | ....
PNQLQEDPTRYNYFYLQCRHDILQGRHPCPHEEECLQLAALQVQIEYGDYDPEETNNKKMTKHVQKYKSYKRFLPKQWIDSIKQSFMHYQMHHKEWRKRI

GELHKLHRGQLPADAEYNYLEHAKRLE-LYGIDLH
 |.|| |.|. |..|. .||....|.. .||....
MEWHKNHCGMTPEEAKLKYLQICQRWPPMYGVEHF

FERM_C Ptpmeg.AA FERM_C 236-326 43 1.5e-40 145.81 Pfam 1-99 (99) Show / Hide
Range on Protein: 236-326
Range on HMM: 1-99/99
Sequence Identity: 43% (43 aa)

DSNGKE-LQLGVSAVGLLVF--QHSLRV---NTFSWSKMVKVSFKRKDFFIQLR--REPSENYDTLLGFGMSSHKHAKALWKSCVEHHSFFRLKRPHRL
|..| . . |||.|.|..|.  |.  ..   |||.|.. .|.||||| |||.||  ..  |.|.. ..| |.... .| |||.|||||.||||.||.  
DKKGTDTWWLGVCAKGINVYQVQDNNKITPMNTFPWPEIRKISFKRKKFFIKLRDDPDEGEKYEHTHTFYMPNYRACKYLWKCCVEHHQFFRLRRPPDT

FERM Ptpmeg.AA FERM_M 123-232 24 3.7e-36 125.28 Pfam 1-171 (171) Show / Hide
Range on Protein: 123-232
Range on HMM: 1-171/171
Sequence Identity: 24% (42 aa)

DPSR-LQEEFTRYQFYLQIKRNILLGKLPCSSNTQCLLASYTVQSELG-DFN-ALEHQPGY-LSGM-------------------QLLC-----------
||.| .|.| ||.|||||.|..|| |..|||  . ..||.| .|.|.| |.| . .| ..| ..                     ...            
DPNRDIQDEVTRHQFYLQAKWDILEGRYPCSEEEALMLAAYQCQIEFGSDYNPPQKHKSDYMEKEWWEQQEGMEVWLRCDNEQQERYWPAHCRLASKGRT

--------------------------DQTTEAERKVGELHKLHRGQ-LPADAEYNYLEHAKRLELYGIDLH
                           .. . |... |.||.|||.  |..|...|.....|.. ||....
MADSSYSEVSIRINPHCYVSPWYCKKMKQKQWEQRILEQHKNHRGMCSPEEAMLQYIQICQRWPMYGVHFF

FERM Ptpmeg.AA FERM_N 38-121 32 6.9e-29 106.19 Pfam 1-93 (93) Show / Hide
Range on Protein: 38-121
Range on HMM: 1-93/93
Sequence Identity: 32% (30 aa)

VLFLDDITHTFRIEKRAKGSELLDQVFQYLELSERDYFGLLF--PQKPG--DVV-RWVDAQKQFKKQCSS----VSLDNDAVPLLEFRVKFFV
|..||| .... ..|...|.||.|||.|.|.. |..|||| |  ....   ..  .|.|. |  .||...     ...... ..| |||||..
VHLLDDTQLECTCDKKTTGQELFDQVCQHLNIRECWYFGLQFCKQNDKKEGNQHMHWLDPDKKICKQMKDGWKHKIKKKCPPCTLFFRVKFYP

PDZ Ptpmeg.AA PDZ 504-589 30 8.7e-22 77.21 Pfam 1-86 (86) Show / Hide
Range on Protein: 504-589
Range on HMM: 1-86/86
Sequence Identity: 30% (27 aa)

TIRLQAD-EQGRYGFNVKGGVDLS--LPVQVSKVVPHTPADRCTPRVCEGDEVLMINGRDVHGLRHEQVVAMIRDCRHQASGELLLTVR
...|. . ..|. ||..||| | .   .. .|.|.|  .|. . .| .||| .. |||.|. ...|...|..|....    ||. ||..
QVTLEKQDKRGGLGFSIKGGNDQRHDQGIYISEVMPGSGAAERGGRIHEGDQIISINGQDIRNMTHDRAVQAIKGSKG---GEVHLTIQ

FA Ptpmeg.AA FA 327-375 44 2.1e-19 71.49 Pfam 1-48 (48) Show / Hide
Range on Protein: 327-375
Range on HMM: 1-48/48
Sequence Identity: 44% (22 aa)

SRFLNISLGSKFYYSGRTELQAVQESKQRGRIHKVFVRSPSKRLLGAAG
.||. .|.|||| |||||. |....|....| .. |.|||||| .  . 
KRFF-CSWGSKFRYSGRTQYQTIEYSREHQRKPPQFHRSPSKRYPSRRS

Phosphatase Ptpmeg.AA PTPc 641-960 29 1.5e-99 337.94 SMART 1-308 (308) Show / Hide
Range on Protein: 641-960
Range on HMM: 1-308/308
Sequence Identity: 29% (107 aa)

ALLAQYELMYRKNPDL---------AITEARKPANA--PKNRYR-DISPYDCTRVSLVNS-------LTGDYINANYVNMEIPGGAVNRYIATQGPLAST
 . ...| ..| .|..          .|.|..|.|.   ||||. || .|| ||| | .          .|||||||....   .  .|||.||||| .|
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY---WRPKRYICTQGPLPHT

TTDFWRMVQQESSHLLVMLTTVMES--------GRQKCHQYWPVTGEELQLAEGFSVRCLSEKPDETGSFVFREFVLKDKH----------EQRHIHHMQ
  |||||| |. .|  |||.. ||         || ||||||| .  ...   ...| |.||.  .  ... |.| ....           | | ..| .
IEDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE--PMTYG-HITVTCKSEEKCP-DDYTMRTFEVTNTGCNCKYSMACSETRTVTHYH

YLAWPDHCVPSDPNLFLEFTERVRAARNRTLLQEIEESLKQVRLMDADADADENGGLMRERKCAASNGATPEDETPVSTSVHQCI---------SAANPP
| .|||| ||..|. ||.| ..||. ...   ...                                                 .         . ...|
YTNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYM-N-----------------------------------------------MVSSNSKYHHTCPTGP

VIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAAYM
..||||||.||||.....|... ..|.   | ...||..||.||..|||.  ||.|...||   ..
IVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTEEQYIFCYRCILEYIK

PDZ Ptpmeg.AA PDZ 513-592 29 3.7e-16 60.91 SMART 1-80 (80) Show / Hide
Range on Protein: 513-592
Range on HMM: 1-80/80
Sequence Identity: 29% (25 aa)

GRYGFNVKGGVDLSLPVQVSKVVPHTPADRCT----PRVCEGDEVLMING-RDVHGLRHEQVVAMIRDCRHQA-SGELLLTVRPQR
| .||...|      .. .|.||| .||...     .....||..| .||  .| ...|||.|.|.. |. .    .. |||... 
GGLGFSIVG------GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG

Phosphatase Ptpmeg.AA Subfamily.N3.PD 642-960 55 1.1e-137 448.7 In-house 2-261 (261) Show / Hide
Range on Protein: 642-960
Range on HMM: 2-261/261
Sequence Identity: 55% (180 aa)

LLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSLTgDYINANYVNMEIPG-GAVNRYIATQGPLASTTTDFWRMVQQESSHLLVML
.|||.| .|||.|.|||..||||.|..|||||||.|||.|||.|..| | |||||||||||||. |.||||||||||||.|..|||.||....|.|.|||
vlaqfeelyrkkpglaisaarkpenlaknryrdilpydatrvklkeset-dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivml

TTVMESGRQKCHQYWPVTGEELQLAeGFSVRCLSEkpDETGSFVFREFVLKDKH--EQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARnrtllqei
||..|.||.||||||| |..||... .||||| .|  ||| |.|.||.|||||.  |.|.|...||||||||.||.|.. ||||.||||..|        
ttlverGrvkChqyWPetedelefg-efsvrceke--detksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklr--------

eeslkqvrlmdadadadengglmrerkcaasngatpedetpvstsvhqciSAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQR
                                                  |....||.|||||||||||||||..|||||.||.||||||||||||||||
--------------------------------------------------sgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqr

ACMVQNVSQYRFVCECICAAYM
|..||.||||.||||.|..||.
amlvqtvsqykfvCeailkaye

Phosphatase Ptpmeg.AA Y_phosphatase 666-957 33 3.7e-92 317.28 Pfam 1-243 (243) Show / Hide
Range on Protein: 666-957
Range on HMM: 1-243/243
Sequence Identity: 33% (101 aa)

NAPKNRYRDISPYDCTRVSLV---NSLTGDYINANYVNMEIPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGR-QK-CHQYWPV-TG
| .||||.|| .|| ||| |    .   .|||||||...  |..  ..||.||||. .|  |||||| |. ..  |||...|| || .| ||||||  . 
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDG--PYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKE

EELQLAEGFSVRCLSEKPDETGSFVFREFVLKDKH----EQRHIHHMQYLAWPDHCVPSD-PNLFLEFTERVRAARNRTLLQEIEESLKQVRLMDADADA
.. .   .|.| | ||.   .  .. |.| ...      | | ..| .|..||||.||.. |. .|.| ..|| ...                       
GQPMTYGDFQVTCVSEEH--CPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP-----------------------

DENGGLMRERKCAASNGATPEDETPVSTSVHQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCEC
                               .. .   ||..||||||.||||.....|... .||. . |  ..||..|| ||. |||. .||.|...|
-------------------------------NPDHGC-PPIVVHCSAGCGRTGTFCAIDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQC

ICA
|  
ILE

Phosphatase Ptpmeg.AA Subfamily.N5_RR.PD 662-957 36 1.3e-58 189.7 In-house 19-262 (265) Show / Hide
Range on Protein: 662-957
Range on HMM: 19-262/265
Sequence Identity: 36% (89 aa)

RKPANAPKNRYRDISPYDCTRVSLV----NSLTGDYINANYVNmeIPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPV
. . .. ||||..| | . .||.|     ..   .||||||.    ...  . |.||||||..| .|||||. ||.....|||| . |. ||||..|.| 
evfgsqtknryktilPnensrvllesessededssyinanyik--GydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPd

TGeELQLAEGF-SVRCLSEKPDETGSFVFREFVLKDKHE-QRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNRTLLQEIeeslkqvrlmdadadad
.  .....| .  |    |.  |.  .  |..|||  .. .|...|. | .|||| .| |.| .|.. . |. .|...  .||.|||||||||||. | .
ae-dyeiserygdveikveeiverndysvrklvlkylerversvkhywytdWPdhksPddintlldlvleveesreeenakla-----------------

engglmrerkcaasngatpedetpvstsvhqcisaanpPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECI
. |.  ..... |  |||  .| .|  |||. .||... . .|                                                         
--------------------------------------PvvvhcsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihral

CA
  
cl

Phosphatase Ptpmeg.AA Subfamily.N6.PD 657-832 38 8.7e-52 167.5 In-house 31-220 (295) Show / Hide
Range on Protein: 657-832
Range on HMM: 31-220/295
Sequence Identity: 38% (74 aa)

AITEARKPANAPKNRYRDISPYDCTRVSLVNS---LTG-DYINANYV--------NMEIPGGA--VNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTT
.|..|. |. ||||..| |.| ||| | .    ..| |||||||.        . | ..     .|||||||.| .| .|||||| || |...||.|  .
srkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdFWrmvwqensrvivmttk

VMESGRQKCHQYWPVTGEELQlAEGFSVRCLSEkpDETGSFVFREFVLK---DKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNR
| |..|| .||| .... .     .|...||  ..| ....|||...   ...|.|.|..... ||||| ||.||. .|.| | |.. ...  
evergknkCarYWPdeetkke-tGvitvtsisE--kstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfledvnkkqee

Phosphatase Ptpmeg.AA Subfamily.RB.PD 646-833 40 5.6e-50 161.4 In-house 6-190 (261) Show / Hide
Range on Protein: 646-833
Range on HMM: 6-190/261
Sequence Identity: 40% (76 aa)

YELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSL---VNSLTGDYINANYvnmeIPGGA-VNRYIATQGPLASTTTDFWRMVQQESSHLLVMLT
|| . . . | |...|....|  |||.. | ||| .|| |    .. . |||||||    |||    . |||||||| .|. |||||| .. |..|||| 
yeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinany----ipgynspreyiatqGPlpetvddfWrmvwekkssiivmlt

TVMESGRQKCHQYWPVTGEELQLAEgFSVRCLSEKpdETGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNRT
..| |..||..||| . |. .  .  .|  |.||  |. ..| ||| .. ..|.|.........|||| ||....  |.|...|| |...  
qlvEkgkekceeYWPadeepvlyGd-ikvtllaek--eldewvirefkiekgkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekk

Phosphatase Ptpmeg.AA Subfamily.N12.PD 647-831 37 2.1e-46 149.5 In-house 13-196 (270) Show / Hide
Range on Protein: 647-831
Range on HMM: 13-196/270
Sequence Identity: 37% (69 aa)

ELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSLT---GDYINANYVNMeiPGGaVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTV
.  |...   . ....|. |  ||||.|| ||| .|| | .       ||||||...   . |   .|||.||||..| .|||||... . ...||.  .
sekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdyinanfikg--veg-kleyiaaqgPLpktlddfWrmiweknveivvmaCre

MESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKPDETGsFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARN
.| |..||..||| .|||    . |.| . .||  . . |. | . .. ..|.|... ..| ||||| ||| ..  ||..| ||..  
velgkkkCeryWpeegeeelefgefevtleeekavddd-flirtLkveaqkesrkvyqfhytaWPDhgvPssaksllelielvrelqe

Phosphatase Ptpmeg.AA Subfamily.N_Choan_1.PD 645-832 36 2.4e-46 149.5 In-house 5-190 (262) Show / Hide
Range on Protein: 645-832
Range on HMM: 5-190/262
Sequence Identity: 36% (70 aa)

QYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSL---VNSLTGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLT
.|| ..  . | . | .....|  ||||..|. || ||| .    .. . ||||||.|.        ..|||||||. .. ..||.|| ... ...||.|
eyeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgy---kgekeyiatqgPvPaslvsfWqmvweqkvsaivmvt

TVMESGRQKCHQYWPVTGEELQLAEgFSVRCLSEKpdETGSFVFREFVL-KDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNR
  .|.|. |||.|||   .||.|.. . |. |||.  |. ... |.| | ... |.|......|.||||| ||.... .||| . |. |...
reieagklkChryWPdenselklgd-vtvkslsee--ekktyierkfkleresgetreveqlaytaWPdhGvPattkellefrkavlkatkk

Phosphatase Ptpmeg.AA Subfamily.R_Sponge_2.PD 650-832 35 1.1e-45 147.4 In-house 9-191 (262) Show / Hide
Range on Protein: 650-832
Range on HMM: 9-191/262
Sequence Identity: 35% (64 aa)

YRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVN--SLTGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESG
.|. .  ...|... | .|||...| ||| .|| | .  | ..|||||..|.        . |||||||| .|  ||||||.. .|||| . | |..||.
veketefslsiaklkenvgKnRfkeilpydmsRvrLrtdgskdsDYinAsfvdgy---krrkayiatqgPlketveDfWRmvweykvstivmltnleeng

RQKCHQYWPVT-GEELQLAEGfSVRCLSEKpdETGSFVFREFVLKDKHE---QRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNR
.||| . .|| .. .   |   .|.  ..  .. |.. |.....   .... . ...|||.| ||.|.||. .||. |...        
kekcakYWPekvdeeveygkf-kvtlkeee--kladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkk

Phosphatase Ptpmeg.AA Subfamily.N13.PD 653-829 35 2.5e-45 146.3 In-house 13-187 (259) Show / Hide
Range on Protein: 653-829
Range on HMM: 13-187/259
Sequence Identity: 35% (64 aa)

NPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSLTgdYINANYVNMEIpGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCH
.| .  ....| .|  |||||.. ||| ||| | .. .  ||||....... |    .|||.||||  |..|||.|| . ......|.|.  |.|. |||
kpldtcevgkkkenkdknryrnvlPydetrvklgdegg--yinaslikvpv-gedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkch

QYWPVTG-EELQLAEGFSVRCLSEkpDETGSFVFREFVLKDKH--EQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAA
.|||..  ..|.. . . |. |     .  .|| |.. .||..  | |.. |... .|||| ||| .. ...|  .||  
rywPerknkklkvsnrlevellkv--qkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrll

Phosphatase Ptpmeg.AA Subfamily.N1.PD 655-829 42 2.6e-44 142.9 In-house 17-190 (268) Show / Hide
Range on Protein: 655-829
Range on HMM: 17-190/268
Sequence Identity: 42% (76 aa)

DLAITEARKPANAPKNRYRDISPYDCTRVSLVNSLTgDYINANYVNMEIpggAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQY
.|  .||..|.| ..|||||.|||| .|. | .. . |||||. |..|    |  ||| |||||. |.. ||.|| .. |. ..||  |.| ...||.||
eletreaklpenrglnryrdvspydhsrikleradv-dyinaslvelee---akrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqy

WPVTGEE--LQLAE-GFSVRCLSEkpDETGSFVFREFVLKD--KHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAA
||   ||  |.| |  ..|. .||  ...  |. | . |.|  ..| | | | .|  |||  ||. |..||.|  .|| .
wpqeeeeaellleetklkvklise--erksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvres

Phosphatase Ptpmeg.AA Subfamily.N14.PD 644-833 35 4.2e-44 142.1 In-house 4-196 (275) Show / Hide
Range on Protein: 644-833
Range on HMM: 4-196/275
Sequence Identity: 35% (68 aa)

AQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSL--TGDYINANYVNMEIpGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLT
..|| . .|. |  .. |. | ||.|||..|. ||. .|| |. .   . .||||  ... . ||.   ||..||||  | .|||.|| ...|.||||  
teyeripkkredallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsv-ggkersyivaqgPleltvqdfwqmvweqgvqlivmlt

TVMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKPDETGSFVFREFVLKD--KHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNRT
 |.|..|...|.| .... . .|    .  ..  ....|.. . . ||    .|.| ..|.||  |||| ||.|.. ||.| |.|.. |..|  
eeeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrkt

Phosphatase Ptpmeg.AA Subfamily.N9.PD 643-832 36 5.8e-44 141.9 In-house 3-192 (275) Show / Hide
Range on Protein: 643-832
Range on HMM: 3-192/275
Sequence Identity: 36% (68 aa)

LAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVN---SLTGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVM
.|. . ....   .. ....||  |||| |.  || ||| | .   . . ||||||.|.        . .|||||||  |..|||||| ....|| | |.
skeyadirnepveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGy---kqkkafiatqGplkktvsdfwrmvweqevlvivm

LTTVMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKpdETGSFVFREFVLK--DKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNR
| || || |||| . |. .    .||. .. .  ..  ...| ...|  ...|.|.. | |.|.|||. |||. . .|.. |.|| ..       
ttrvvergrlkcgqywpleeessaefgdlsvsnveve--veedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqal

Phosphatase Ptpmeg.AA Subfamily.R_Anemone_2.PD 644-830 35 8.6e-44 141.3 In-house 4-189 (262) Show / Hide
Range on Protein: 644-830
Range on HMM: 4-189/262
Sequence Identity: 35% (69 aa)

AQYELMYRKN-PDLAITEARKPANAPKNRYRDISPYDCTRVSLV---NSLTGDYINANYVNMEIpggAVNRYIATQGPLASTTTDFWRMVQQESSHLLVM
..|| . |..   . ...| .|.|. |||| .| .|| ||| |    .. . |||||||..      . . |||||.||. | .|||||| .  | ..||
eeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyr---rkkayiatqaPlpetiedfWrmvWeqnsavivm

LTTVMESGRQKCHQYWPVTGEelQLAEGFSVRCLSEKpdETGSFVFREFVLKDK--HEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAAR
|| ..|.|..|.|.||| .|   .  .   |   .|.  |....| |.| .| .  .|.|...  .| .|||. ||...  .|..  .|..| 
ltqeeergkakvhryWPskgs--rsygklvvelkeev--elsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaq

Phosphatase Ptpmeg.AA Subfamily.R_Anemone_1.PD 652-830 34 9.8e-44 141.2 In-house 11-186 (258) Show / Hide
Range on Protein: 652-830
Range on HMM: 11-186/258
Sequence Identity: 34% (62 aa)

KNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVN---SLTGDYINANYVNMEIpgGAvNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGR
....     |||..|  |||| || ..| .|| | .     ..||||| |..     .  . .||||.|| .|. |||||| ||.  .||||...|.  .
eikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasd--kt-rafiatqapleetvedFWrmvwqekigviVmLtnliegek

QKCHQYWPVtgeELQLAEGFSVRClsEKPDETGSFVFREFVLKDK--HEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAAR
|||||||    . .    ..|.   .| .. . .. |..||. |  .|.|........ |||..||.|.. ..|.. .      
kkchqYwPd---stekygelrvsl--rkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqkss

Phosphatase Ptpmeg.AA Subfamily.RG.PD 644-831 33 3.2e-40 129.5 In-house 4-193 (264) Show / Hide
Range on Protein: 644-831
Range on HMM: 4-193/264
Sequence Identity: 33% (65 aa)

AQYELMYR-KNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSLT--G-DYINANYVNmeipG-GAVNRYIATQGPLASTTTDFWRMVQQESSHLLV
.|.|.. . |. |. .. ..|. |  |||. .| ... .||.| .     | |||||.|..    |    . ||.|||||..|. |||||. ......||
eqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyid----GyrrskeyivtqgplketiedFWrmiWehnaqiiv

MLTTVMESGRQKCHQYWPVTGEELQlAEGFSVRCLSEKPDetGSFVFREFVLKDK----HEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARN
|| . |.||.....|||   | |.  | ..|. ||..     ... |.||||..    ...|.... .|  |||...|.    .| |..  ||..  
mltdldekgrrdedvyWPkkdeple-lealkvtllskekl--skytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaank

Phosphatase Ptpmeg.AA Subfamily.N_Choan_2.PD 666-818 36 1.5e-38 123.8 In-house 21-174 (266) Show / Hide
Range on Protein: 666-818
Range on HMM: 21-174/266
Sequence Identity: 36% (56 aa)

NAPKNRYRDISPYDCTRVSLVN---SLTGDYINANYVNmeIPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEEL
|.  |||.|| |   ||| | .     .  |||||||.     |. ..|||..|||..|...||||. .| .. .||.| ..| ||.|| .|||   .| 
nkrlnRyndiLPsPatRvrleeleedsataYinAnyvr--GfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkek

QLAEGFSVRCLSEKPDETGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNL
   .   .. |...   .  .....  |. |.|.|.. | .| .|||| ||.... 
vkladgkikvlalseekeegyiltrlrlekkgetrrlvHfwyntWpdhgvpreeds

Phosphatase Ptpmeg.AA Subfamily.RK.PD 660-830 33 4e-36 115.8 In-house 23-194 (267) Show / Hide
Range on Protein: 660-830
Range on HMM: 23-194/267
Sequence Identity: 33% (59 aa)

EARKPANAPKNRYRDISPYDCTRVSLVN--SLTGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTV-MESGRQKCHQYWP
| |. |  |||. || .|| ..| |.       |||||....        . .|.||||| .|..||||.| .| .  .|||| . .| || || .||| 
iakkdrnreknrsmdilaydrslvflisvdgdssdyinaalidsy---krpaafivtqgPlqetvkdfWrlvydencasivmlteldvevgrvkClkyWP

VTGEElqLAEGFSVRCLSEKPDEtgSFVFREFVLKD----KHEQRHIHHMQYLAWPDH-CVPSDPNLFLEFTERVRAAR
 .|       . | ... ..|.   .| | | ..     ..|.| ....|.|.||..  ||   . .|..  || . . 
edtev--rygdikvelveaelda--dlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksq

Phosphatase Ptpmeg.AA Subfamily.RA.PD 659-831 29 5.3e-35 112.4 In-house 20-194 (266) Show / Hide
Range on Protein: 659-831
Range on HMM: 20-194/266
Sequence Identity: 29% (53 aa)

TEARKPANAPKNRYRDISPYDCTRVSLVNS---LTGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYW
| |..|  |||. .| ||| .|| | .     . ||||| ...        ...||.|||.. |  |||||. .  |. .|||| . | ...||.|||| 
rtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGy---rekdkfiaaqGpkeetvedfwrmiweqksativmltelkerkeekcaqyw

PVTGeelQLAEGfSVRCLSEKPDETGSFVFREFVLK------DKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARN
 |    .. |  .|   ..  .. ..  |.|...      .....| .. . . .||.  ||...   |.. ..|.. ..  
pdeG---lvtyG-eirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqq

Phosphatase Ptpmeg.AA Subfamily.N_Nematode_1.PD 643-832 32 7.3e-35 111.8 In-house 3-198 (265) Show / Hide
Range on Protein: 643-832
Range on HMM: 3-198/265
Sequence Identity: 32% (65 aa)

LAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSL-VNSLTGDYINANYVNMEIPGgavNRYIATQGPLASTTTDFWRMVQQESSHLLVMLT
.... . . |.   ..  ..  .| ||||.|..  | .|| |  ..|. ||| |||| . .     .|.| .|.|| .|..||| || ||    .|||  
rdefralkkfndeekvkafkeaqeadknrykdvgcldknrvklaeeplpsdyihanyvgtptnp---krficaqaPldktiadfwymvlqekveaivmlc

TVMESGRQKCHQYWPV-TGEELQLAEG---FSV-RCLSEKPDETGSFVFREFVLKDK---HEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNR
..| |..||..|.|. .||.|.. |.    .|   |. |. |. . | .. ||. .   ...|...|.|.  |||. ||.     ||. |.||. ..  
kliekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrgskgP

Phosphatase Ptpmeg.AA Subfamily.R_Ecdysozoa.PD 644-830 30 1.3e-34 110.9 In-house 4-192 (269) Show / Hide
Range on Protein: 644-830
Range on HMM: 4-192/269
Sequence Identity: 30% (59 aa)

AQYELMYRK-NPDLAITEARKPANAPKNRYRDISPYDCTRVSLVN---SLTGDYINANYVNMEipgGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVM
|| . .. . ..  . . |  || ||||.|| ..| ||| | .   . . |||||....        ...|| |.|. .|  |||||. . ...|.|||.
eeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgy---kekkkfiaaqdPveatigDfWrmiaeqevtlivm

LTTVMESGRQkCHQYWPVTgEELQLAeGFSVRCLSEKpdETGSFVFREFVLKDKH-----EQRHIHHMQYLAWP-DHCVPSDPNLFLEFTERVRAAR
 . |  |. |..|||.  .| |      |.. ||.  ... .. ||. .  |.     ..|..   .|.|. |  ||  ..  |.. |.||      
lsnlteknrk-cakyWpie-devqyg-dilvklvsee--khsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrely

Phosphatase Ptpmeg.AA PTPc_motif 798-957 24 2.3e-34 121.43 SMART 1-92 (92) Show / Hide
Range on Protein: 798-957
Range on HMM: 1-92/92
Sequence Identity: 24% (40 aa)

HIHHMQYLAWPDH-----CVPSDPNLFLEFTERVRAARNRTLLQEIEESLKQVRLMDADADADENGGLMRERKCAASNGATPEDETPVSTSVHQCISAAN
 .||..|..||||     .||.  . .||| ..||.                                                                
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK----------------------------------------------------------------

PPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICA
 |..||||||.||||.....|... .      |  ...|. ||.||. |||.  ||.|...||  
-PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQYIFCYRCILE

Phosphatase Ptpmeg.AA Subfamily.N23.PD 682-830 34 9.2e-34 108.3 In-house 118-268 (350) Show / Hide
Range on Protein: 682-830
Range on HMM: 118-268/350
Sequence Identity: 34% (53 aa)

RVSL----VNSLTGDYINANYVNMEIPGgaVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKp
|| |      . . ||||| |.    |.     .||||||.||| .||| || .. | ..||||.  | ...||.||||   .| .| . ..|. |..  
rvklqqstqpgqqddyinatylkeltpm--sPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslkslr-

dETGSFVFREFVLK--DKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAAR
..  .. | . |.  | .  |.. |... .|... ||. |. .|.| . |..|  
-ssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetay

Phosphatase Ptpmeg.AA Subfamily.N20.PD 658-827 37 1.3e-33 108.0 In-house 18-184 (257) Show / Hide
Range on Protein: 658-827
Range on HMM: 18-184/257
Sequence Identity: 37% (64 aa)

ITEARKPANAPKNRYRDISPYDCTRVSLVNSltGDYINANYVNMeIPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPV
.    .|.|  ||||||| |||.||| | .|   |||||.|. . .  |    |||||||| ||  |||.|| .. | .. |.|  .| |  ||..|||.
fnsgnqpsnreknryrdilpydstrvplgks--kdyinasyiri-vncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywpi

TGEELQlaEGFSVRCLSEKPDETGSFVFREFVLKDKH--EQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVR
. ..    |   .| . |. .    |. | | . .|     . ....|.  ||||  |.  . |...    |
slkkpl--elkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryar

Phosphatase Ptpmeg.AA Subfamily.RN.PD 650-827 34 3.7e-33 106.1 In-house 12-188 (264) Show / Hide
Range on Protein: 650-827
Range on HMM: 12-188/264
Sequence Identity: 34% (63 aa)

YRKNPDlAITEARKPANAPKNRYRDISPYDCTRVSLVN---SLTGDYINANYVNMEIPGGAVnrYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMES
|. .|  . . |... |. |||.... ||| .||.| .   . . |||||  .  . |  ..  ||||||||.|| .|||.|| .. . ..|.||.. |.
yeaeps-tkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapa--yiatqgplsstiadfwqmvweqGvvvivnltrleee

GRQKCHQYWPVTGEELQlaEGFSVRCLSEKPdETGSFVFREFVLKD--KHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVR
| ..|..||| .|.|.   . . |. .||.   .  .. | | ||.  ..| | .  . .|.||.. ||. .. .|||  .| 
gvkqckrywpdeGsevy--hiyevhlvsehi-wcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvn

Phosphatase Ptpmeg.AA Subfamily.R_Nematode_2.PD 656-828 32 1.3e-31 101.1 In-house 19-191 (261) Show / Hide
Range on Protein: 656-828
Range on HMM: 19-191/261
Sequence Identity: 32% (54 aa)

LAITEARKPANAPKNRYRDISPYDCTRVSLVNSLTGDYINANYVNMeipGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYW
.||  . ... |.|| |.   . |.|  .   .   | ||.|.     |  .|.|||||||  |. ||| ||.||    .|||. ..|. ..||..|.|.
esvtesaaylpkdkhRypdvPCkpetavevivdgkrvpihanwvpt---agnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYf

PVTGEELQLAEGFSVRCLSEKPDETGSFVFREFVLKDKHE---QRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRA
. ..    . ||.. .|..   . .   | .  .|.      | ..|.||  |||. |||  | |.          
pletsqkldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkk

Phosphatase Ptpmeg.AA Subfamily.N_Nematode_4.PD 658-829 30 3.8e-30 96.4 In-house 18-193 (264) Show / Hide
Range on Protein: 658-829
Range on HMM: 18-193/264
Sequence Identity: 30% (53 aa)

ITEARKPANAPKNRYRDISPYDCTRVSLVNS-LTGDYINANYVNMEipggAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWP
.|     .|. ||||.||   | ||| | |     ||| |... |        |||.|||||  | .||| || .|  . .|||. .| | .|| .|.| 
vtasaseknsdknryadilcidetrvvlknrdpdndyihaswmrmP----dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryyp

VTGEELQLAEGFSVRCLSEKPDETGSFVFREFVLKDKH-------EQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAA
. |. .    . .. . .|       ... . .   .       |.  ..|.|.  |.|.  | |....   |.      
eksekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkkk

Phosphatase Ptpmeg.AA Subfamily.RC.PD 642-827 30 1.2e-29 94.8 In-house 2-203 (288) Show / Hide
Range on Protein: 642-827
Range on HMM: 2-203/288
Sequence Identity: 30% (63 aa)

LLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSL---------------------VNSL-TGDYINANYVNMEIpggAVNRYIATQGPLA
|.|... . .     .| .|||. |  |||| |. |||  || |                     ..|  . .|||| ...        ..|||.|||| 
leaefqrlpsvrskrtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsyk---kpekyiaaqGplk

STTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWpvtgEELQLAEGFSVRCLsEKPDETGSFVFREFVLKDKH--EQRHIHHMQYLAWPDHCVPSDPN
 |  |||||. ..  ...|||| . |  |.|| .||    || . | |  .  | .. | . ....| . |..|   . |.. ..||.|... .| .|..
etvddfwrmiferkvkvivmltelkeGdrekcaeyw----eeGkrayGdvevdl-kdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepk

LFLEFTERVR
.|.. . |. 
ellkliqvvk

Phosphatase Ptpmeg.AA Subfamily.N_Fungi_PTP1.PD 668-757 36 4.3e-26 83.0 In-house 47-150 (343) Show / Hide
Range on Protein: 668-757
Range on HMM: 47-150/343
Sequence Identity: 36% (37 aa)

PKNRYRDISPYDCTRVSLVN-----------SLTGDYINANYVNMEIPGGAVN---RYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQ
||||..| ||. .|| | .             | |||||||.... ..  .|   .|||||.|| ||  ||.... .   .....||. .| ...||..|
aknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyr

YWPV
|.  
YWqe

Phosphatase Ptpmeg.AA Subfamily.R_Nematode_3.PD 666-829 27 7.1e-26 82.4 In-house 23-197 (267) Show / Hide
Range on Protein: 666-829
Range on HMM: 23-197/267
Sequence Identity: 27% (49 aa)

NAPKNRYRDISPYDCTRVSLVN---SLTGDYINANYVnmEIPGGavNRYIATQGPL--------ASTTTDFWRMVQQESSHLLVMLTTVME---SGRQKC
.  ..|. ... .  ||| |..    .. |.|.||.|  |.|.|  .. | ||.|.        .||   || |..|| .. .|||  ..|   .. .||
kvsedrrvevpllektrvvLkgygkrfkddfihAnvv--ecpng--lklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeeekc

HQYWPVTGEELQLAEGFSVRCLSEKPDETGSFVFREFVLK-DKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAA
 .|.|   .. .  ||.||.| . | .   ... |..|.. .|...  ..|..| .|... .| .|..||  . |..  
seYypekvdgelkfegvsvkctdikkelsedvekrtlvvtfekkkeftvthllykgWkelnapeepkealelikfveks

Phosphatase Ptpmeg.AA Subfamily.N_Nematode_6.PD 665-815 27 6.6e-25 79.3 In-house 23-170 (253) Show / Hide
Range on Protein: 665-815
Range on HMM: 23-170/253
Sequence Identity: 27% (42 aa)

ANAPKNRYRDISPYDCTRVSLVNSlTGDYINANYVNMEIpggAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPV-TGEELQ
..  .|||..|  .|..|. |..     || ||.|..       .|.| ||.|| .| ..||.|.    .. .|||  ..|.|..|. .| .   |.. .
kfkdrnrytniqCcdagrlkladd-edfyihanlvkist---kprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvGdark

LAEGFSVRCLSEK-PDETGSFVFrEFVLKDKHEQRHIHHMQYLAWPDHCVPSD
...  .|  ...|  | . . .    . |. .|.  ..|... .|||| || .
itklctvikigrkdidkilvrsl-krivkagdeevivkhihWanWPdhGvPds

Phosphatase Ptpmeg.AA Subfamily.N_Nematode_egg.PD 647-804 26 2.2e-21 67.7 In-house 7-165 (257) Show / Hide
Range on Protein: 647-804
Range on HMM: 7-165/257
Sequence Identity: 26% (44 aa)

ELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLV---NSLTGDYINANYVNmeiPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTV
| . |   . ..|.| .  .  | | . .   . .|| |       ..|.| ||.|.    .  .| .| .| ||  |  |||||| ||  . .||||. 
eilersvdeislttaasdnylekarskrvhckessrvklelrrGqylddfihanrvk---Gkpllnefilaqaplkntvedfwrmvfqekvqyivmltsa

MESgrQKCHQYWPVTGEELQLA--EGFSVRCLSEKPDETGSFVFR-EFVLKDKHEQRHIHHMQY
.||  ..|. ||| . .|       .. . .|  .      |      ..  ..|.... | |.
kes--erceyywpkaeseslvtvpGslrienlkvdskadplfrvtklklvGgddeelflehwqg

Phosphatase Ptpmeg.AA Subfamily.RB.PD 888-957 38 4.2e-21 66.8 In-house 187-258 (261) Show / Hide
Range on Protein: 888-957
Range on HMM: 187-258/261
Sequence Identity: 38% (28 aa)

IS--AANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICA
|.  |.. |..||||||.||||. | .|. |  .|... |  . .|  .| .|...||. .|| |. ||. .
iekkaskkPivvHCsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclld

Phosphatase Ptpmeg.AA Subfamily.N14.PD 884-955 42 2.2e-20 64.3 In-house 199-270 (275) Show / Hide
Range on Protein: 884-955
Range on HMM: 199-270/275
Sequence Identity: 42% (30 aa)

VHQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECI
..    ..|||.||||||.|||||||| |  .| .|  | .    .....| ||  .||...||.|| . . 
evesvkeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvl

Phosphatase Ptpmeg.AA Subfamily.N_Choan_2.PD 890-955 41 2.5e-20 64.0 In-house 197-261 (266) Show / Hide
Range on Protein: 890-955
Range on HMM: 197-261/266
Sequence Identity: 41% (27 aa)

AANpPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECI
|. |..||||||.||||.||..|.|. |.| .. | .| |.. .| .|  .|| . ||... . . 
kae-PllvHcsaGvgRtGtliaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykav

Phosphatase Ptpmeg.AA Subfamily.N13.PD 888-955 45 3.4e-20 63.9 In-house 187-254 (259) Show / Hide
Range on Protein: 888-955
Range on HMM: 187-254/259
Sequence Identity: 45% (31 aa)

ISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECI
.   . |..|||||||||.|||| .|..| |.|  ...   .|||..|.||  .||   || || . |
lqtdagPivvhcsaGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykai

Phosphatase Ptpmeg.AA Subfamily.N_Nematode_5.PD 665-817 24 4.5e-19 59.9 In-house 24-172 (258) Show / Hide
Range on Protein: 665-817
Range on HMM: 24-172/258
Sequence Identity: 24% (38 aa)

ANAPKNRYRDISPYDCTRVSLVNSLtGDYINANYVNMEIpggAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKChQYWPVTGEELQL
.|  |||. |.  .| |||.| .    .||||......    . ...| || || .|. |||||| ||. ...|.|..  |  .... ...| . .. . 
knlkknrskdvkilDetrVkltded-dsYinaskikldd---lekkliltQlPlpdteedFWrmvyqekitsvvllvedeelketav-sffpletgdyln

AEGFSVRCLSEKPDETG--SFVFrEFVLKDKHEQRHIHHMQYLAWPDHCVPSDPN
.... ...   . .|.    ... | . ... |.  ... ..  |... ||.. .
lgkmfinnrkvevkedekkeytv-evlpegcsesvfakvyhlttWkkkkvPdkvk

Phosphatase Ptpmeg.AA Subfamily.N_Choan_1.PD 887-957 32 1.3e-18 58.6 In-house 187-259 (262) Show / Hide
Range on Protein: 887-957
Range on HMM: 187-259/262
Sequence Identity: 32% (23 aa)

CIS-AANPPVIVHCSAGIGRTGVLILMDTALALMEAREPV-YPLDIVRTMRDQRACMVQNVSQYRFVCECICA
. .   . |...|||||.||||. | .|...  .|.....  . ..|. .| .|  ||| . ||.||  ..  
atkkktkaplvihCsaGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavld

Phosphatase Ptpmeg.AA Subfamily.N12.PD 885-956 35 3e-18 57.2 In-house 192-266 (270) Show / Hide
Range on Protein: 885-956
Range on HMM: 192-266/270
Sequence Identity: 35% (26 aa)

HQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREP---VYPLDIVRTMRDQRACMVQNVSQYRFVCECIC
..  .. . |..||||||.||||..| .| .  |..|.     .   |.| ..| |||..||   ||..| ... 
relqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykava

Phosphatase Ptpmeg.AA Subfamily.RA.PD 889-955 41 1.9e-17 54.8 In-house 195-261 (266) Show / Hide
Range on Protein: 889-955
Range on HMM: 195-261/266
Sequence Identity: 41% (27 aa)

SAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECI
|| |..||||||.|||| .| .|. |. ..| . .   ..|...| ||. |||   || |. . .  
qsanhpivvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvl

Phosphatase Ptpmeg.AA Subfamily.N9.PD 889-953 45 2.2e-17 54.7 In-house 204-268 (275) Show / Hide
Range on Protein: 889-953
Range on HMM: 204-268/275
Sequence Identity: 45% (28 aa)

SAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCE
. .||..||||||||||| .| .| .|| .|  . |   . |...| ||| ..|   || |    
hlsgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcyl

Phosphatase Ptpmeg.AA Subfamily.R_Anemone_2.PD 889-956 40 2.4e-17 54.6 In-house 191-258 (262) Show / Hide
Range on Protein: 889-956
Range on HMM: 191-258/262
Sequence Identity: 40% (27 aa)

SAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECIC
.. . |..||||||.||||| | .|. |  ..| . |  ...|...|.||  |||  .|| |. . . 
esgagpivvhcsaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvll

Phosphatase Ptpmeg.AA Subfamily.N_Nematode_5.PD 873-956 24 7e-16 49.5 In-house 167-254 (258) Show / Hide
Range on Protein: 873-956
Range on HMM: 167-254/258
Sequence Identity: 24% (21 aa)

TPEDETPVST-SVHQCISAA---NPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECIC
|.....| .  ... .|     |.||.|....|.||.| ..|...|   ... . .   .|....|.||...|....|| .|...   
vPdkvkkvikraiekvlskkqgknapvvvvsdlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaavl

Phosphatase Ptpmeg.AA Subfamily.N6.PD 890-956 40 7.6e-16 49.5 In-house 222-291 (295) Show / Hide
Range on Protein: 890-956
Range on HMM: 222-291/295
Sequence Identity: 40% (27 aa)

AANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIV---RTMRDQRACMVQNVSQYRFVCECIC
. |..||||||||||| .|..|. | ..| .   ...||    ...| ||. .||   ||.||  ..   
ekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavq

Phosphatase Ptpmeg.AA Subfamily.N23.PD 889-955 32 1.5e-15 48.4 In-house 278-345 (350) Show / Hide
Range on Protein: 889-955
Range on HMM: 278-345/350
Sequence Identity: 32% (22 aa)

SAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYP-LDIVRTMRDQRACMVQNVSQYRFVCECI
.... |.|.|||||.||||.. .. .|.. ..|....   ...||..| ||  |||.. ..... | .
geggkPiilhCsaGvgRtgtfcvvysaireltagngiiniprvvrrlrqqRkymvqkkvilkklyeav

Phosphatase Ptpmeg.AA Subfamily.R_Sponge_2.PD 873-955 29 2.3e-15 48.1 In-house 171-257 (262) Show / Hide
Range on Protein: 873-955
Range on HMM: 171-257/262
Sequence Identity: 29% (25 aa)

TPEDETPVSTSVHQ----CISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECI
.|.|.|..   ...         | ...|.||.|.||||  | .|. |  ..| | .   ....|.| .|  .||...|| |. .. 
vPkdatsllelikrvlraqkksgnkaitvvCsdgvgrtGtfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdal

Phosphatase Ptpmeg.AA Subfamily.R_Ecdysozoa.PD 887-955 35 4.2e-15 46.9 In-house 196-264 (269) Show / Hide
Range on Protein: 887-955
Range on HMM: 196-264/269
Sequence Identity: 35% (24 aa)

CISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECI
| .. |..|||||| ||.|... .|  |  ..| . |  ...|. .| ||. .||.. || |.   .  
klsgsrsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyral

Phosphatase Ptpmeg.AA Subfamily.RK.PD 891-956 35 7.2e-15 46.1 In-house 198-263 (267) Show / Hide
Range on Protein: 891-956
Range on HMM: 198-263/267
Sequence Identity: 35% (23 aa)

ANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECIC
. ...|||.|| ||.|. | .|. | ..| .. |    .|.|.|.... ||.   ||.|| . |  
eeGrivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvil

Phosphatase Ptpmeg.AA Subfamily.R_Nematode_3.PD 875-958 25 1.6e-14 45.2 In-house 182-265 (267) Show / Hide
Range on Protein: 875-958
Range on HMM: 182-265/267
Sequence Identity: 25% (21 aa)

EDETPVsTSVHQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEARE-PVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAA
|.  .. ... . . . . ||.||||.||.|...|  .. .  |.  ..  .  |...  .| |||  .|. ... ||  .|.  
eepkea-lelikfveksktpvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgilkl

Phosphatase Ptpmeg.AA Subfamily.N_Nematode_eak.PD 652-822 23 1.8e-14 45.0 In-house 12-178 (281) Show / Hide
Range on Protein: 652-822
Range on HMM: 12-178/281
Sequence Identity: 23% (40 aa)

KNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSLTG--DYINANYvnMEIPGgAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQ
... |.|.....  .  .||  .| |.|   | | .|      ||||    .| .    ..|| |  .  .    ||.|| .. |  .|.|   .| . .
yqrllsirvtarleavnrnrvvkivpqdrylvrltssqlnrdGyinasl--aefse-vGrkyiltGiasedkvfafwqmvleqkspaivqlledveekle

KCHQYWPVTGEELQLAEgFSVRCLSEkPDETGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNlFLEF
|  .|.|  .|.|.    . | . .    . . . .| ..|.   |  ...| ..  | .  .|. || .   
ksdkyfpdktevlkyGi-ldverkey-avkrniletrllilrkGnethrvlhykvfGwtettlpkyed-flal

Phosphatase Ptpmeg.AA Subfamily.N20.PD 891-954 45 5.4e-14 43.7 In-house 188-251 (257) Show / Hide
Range on Protein: 891-954
Range on HMM: 188-251/257
Sequence Identity: 45% (27 aa)

ANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCEC
|..||||||||||||.. .|  .. .     .  .|||  ||.||. |||   ||.|. .    
ltgpmvvhcsagigrtgvflcvdvvfcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcydi

Phosphatase Ptpmeg.AA Subfamily.R_Anemone_1.PD 889-957 37 5.7e-14 43.7 In-house 187-255 (258) Show / Hide
Range on Protein: 889-957
Range on HMM: 187-255/258
Sequence Identity: 37% (25 aa)

SAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICA
| . ||.||||||.||||. . .|. |  . ... |   ..|...| .|. |||  .|| |. . .   
lagarpvvvhCsaGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavle

Phosphatase Ptpmeg.AA Subfamily.N_Nematode_1.PD 888-955 30 5.9e-14 43.3 In-house 189-260 (265) Show / Hide
Range on Protein: 888-955
Range on HMM: 189-260/265
Sequence Identity: 30% (22 aa)

IS---AANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPL-DIVRTMRDQRACMVQNVSQYRFVCECI
..   . . |..||||||||||| .. ..  |  . . . . .  ..|. .|.||.  .|.  || ||   .
leavrgskgPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvl

Phosphatase Ptpmeg.AA Subfamily.RC.PD 889-959 33 6.4e-14 43.1 In-house 217-287 (288) Show / Hide
Range on Protein: 889-959
Range on HMM: 217-287/288
Sequence Identity: 33% (22 aa)

SAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAAY
|..|||..| .|||. | ... |  .|| | |   ..|. .| .|. ||.   || .. . .   |     
nfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlvety

Phosphatase Ptpmeg.AA Subfamily.N_Nematode_4.PD 890-956 37 1.9e-13 41.6 In-house 194-260 (264) Show / Hide
Range on Protein: 890-956
Range on HMM: 194-260/264
Sequence Identity: 37% (24 aa)

AANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECIC
. |..||||||.|||  |. .| |   .     .  ||||| .|  |   ||   |. |.  ..   
kkekPivvhcsaGvGrtatlvGidyatirirenseievldivrelramrlkavqshlqflfllvvli

Phosphatase Ptpmeg.AA Subfamily.RN.PD 884-956 35 2e-13 41.5 In-house 187-260 (264) Show / Hide
Range on Protein: 884-956
Range on HMM: 187-260/264
Sequence Identity: 35% (27 aa)

VHQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEarEPVYPLDIVRT---MRDQRACMVQNVSQYRFVCECIC
| ..      |..||||.| ||||| ||.|  |. .     |  .||. |   .||||. .|.  .|..|.  ...
vnksyrGrscpivvhcsdGaGrtGvyilidlvlerll--kGvkeidiaatlehlrdqrpglvktkdqfefaltava

Phosphatase Ptpmeg.AA Subfamily.RG.PD 870-956 29 2.3e-13 41.5 In-house 171-260 (264) Show / Hide
Range on Protein: 870-956
Range on HMM: 171-260/264
Sequence Identity: 29% (26 aa)

NGATPEDETPVSTSVHQC---ISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECIC
. ..|| ...| ..|..     .... |..||.||| ||.|..| .|| |  .|..| |  .......| .|  .|..  ||.|. . . 
dmgsPestlfvlifvkkeeaankeeaGPivvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydall

Phosphatase Ptpmeg.AA Subfamily.N_Nematode_6.PD 889-956 34 3.8e-13 40.7 In-house 182-249 (253) Show / Hide
Range on Protein: 889-956
Range on HMM: 182-249/253
Sequence Identity: 34% (22 aa)

SAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECIC
. |..||||||.|||| |.|. ..|. .   .     |..  .|..|.  || . || ..  |.    
kkdkkPivvhCsaGvGrtGtlaliliilealrlpdfqgvkdllvklreerfravqtevqylyalrcvl

Phosphatase Ptpmeg.AA Subfamily.N_Fungi_PTP1.PD 889-956 35 7.8e-12 36.1 In-house 257-339 (343) Show / Hide
Range on Protein: 889-956
Range on HMM: 257-339/343
Sequence Identity: 35% (29 aa)

SAANPPVIVHCSAGIGRTGVLILMDTALA----LMEAREPVYPL-----------DIVRTMRDQRACMVQNVSQYRFVCECIC
.|  .|..||||||.||||.|. .|  |     | . ..    |            ||  .| ||  ||||. |. |. |.. 
narsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeall

Phosphatase Ptpmeg.AA Subfamily.R_Nematode_2.PD 890-951 31 8.1e-12 36.2 In-house 191-252 (261) Show / Hide
Range on Protein: 890-951
Range on HMM: 191-252/261
Sequence Identity: 31% (19 aa)

AANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFV
.. |..||||||||||. .| ..     .|| . .   . .. .|..| . .|. ||. .. 
ksekPivvhCsaGiGRtmafigteylareveadptieltealkelrehRwkgiqtesqlywl

Phosphatase Ptpmeg.AA Subfamily.N1.PD 887-954 37 6.4e-11 33.5 In-house 192-262 (268) Show / Hide
Range on Protein: 887-954
Range on HMM: 192-262/268
Sequence Identity: 37% (25 aa)

CISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVR---TMRDQRACMVQNVSQYRFVCEC
..|    |...||||||||.| | |.|| |...|... .  .|| .    .| .|  ..|   | ||    
sLssdvgpavihCsagigrsgtlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyia

Phosphatase Ptpmeg.AA Subfamily.PTPDC1.PD 893-952 35 3.4e-07 21.2 In-house 167-221 (229) Show / Hide
Range on Protein: 893-952
Range on HMM: 167-221/229
Sequence Identity: 35% (20 aa)

PPVIVHCSAGIGRTGVLIlmdtALALMEArEPVYPLDIVRTMRDQRACMVQNVSQYRFVC
. ||| || |||||||    |  |. | . . . . ....|..|.  .|  .| ..|   
gkiavHCHAGlGRtGvli----acylvya-krltaeeaiklvrskrpksiqtreqvelve

Phosphatase Ptpmeg.AA Family.DSP.PD 795-940 15 5.4e-07 20.5 In-house 147-228 (387) Show / Hide
Range on Protein: 795-940
Range on HMM: 147-228/387
Sequence Identity: 15% (22 aa)

E-QRHIHHMQYlAWPDHCVPSDPNLFLEFTERVRAarnrtllqeieeslkqvrlmdadadadengglmrerkcaasngatpedetpvstsvhqC-IsaAN
. . .|..... ...|| .|.  ||| .. . .                                                            ...  | 
tkelgikylri-pidDhnapplenlfekaidfiee----------------------------------------------------------gnd--sk

PPVIVHCSAGIGRTGVLIlmdtALALMEAREPVYPlDIVRTMRDQRAC
||| ||.||.|.||    .  ||...   .. . .. .|..| .    
gvVlVHCkaGkgRsgtli----iaYlmksegltle-ealdwvrskRpg

Phosphatase Ptpmeg.AA Subfamily.N_Nematode_egg.PD 889-955 25 9.1e-07 19.8 In-house 184-252 (257) Show / Hide
Range on Protein: 889-955
Range on HMM: 184-252/257
Sequence Identity: 25% (17 aa)

SAANPPVIVHCSAGIGRTGVLILMDTALALMeAREPVYPLDIVRT---MRDQRACMVQNVSQYRFVCECI
.  ||.|..  |. ....|. ...||  .  | |..   . |.   .| .|   |. | .| ||   .  
rnlskpvvvqdilGvskaatlvaieiallsl-lrGpitkslvlravvflrlrrrlsvesvllylfvyrlv

Phosphatase Ptpmeg.AA Subfamily.PRL.PD 891-950 38 3.7e-06 18.1 In-house 80-132 (140) Show / Hide
Range on Protein: 891-950
Range on HMM: 80-132/140
Sequence Identity: 38% (23 aa)

ANPPVIVHCSAGIGRTGVLIlmdtALALMEArePVYPLDIVRTMRDQRACMVqNVSQYRF
.  | ||| ||.||. ||.    ||||.||   . . | |  .|..|   . |  | .| 
pkstvavhcvaGlGraPvlv----alaliea--Gmkyedavefirekrrgai-nskqlkf

Sequence
Name Sequence Type Origin Length Description Download
Ptpmeg.AA Protein None 974 None Fasta, JSON
Ptpmeg.NA RNA None 2922 None Fasta, JSON
Ptpmeg.AA.PD_641-960 Protein Phosphatase Domain None 320 None Fasta, JSON