Gene PTP-ER
PTP-ER
Species: D.melanogaster
Alias: PTP-ER
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PTP-ER.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | PTP-ER.AA | Subfamily.N1.PD | 890-1002 | 25 | 7.7e-12 | 36.1 | In-house | 4-93 (268) | Show / Hide |
Range on Protein: 890-1002 Range on HMM: 4-93/268 Sequence Identity: 25% (28 aa) RIFRDLHKEFWDLPLNHQEKPMvFGSQTKNRYKTILPNENSRVLLESESSeltsllgeikrtssvtasedlPYINANYIKGPDyVSKCYVATQGPLPNTI |. ...||. . |...| . ....|||. . | . ||. ||... ||||. .. . . . |. ||||||.|. eilleidkeskekeletreakl-penrglnryrdvspydhsrikleradv---------------------dyinaslvelee-akrrYiLtqGPLphta FEFWLMIYQNTQR || |.... . dHFWqmvWeqnsk |
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| Phosphatase | PTP-ER.AA | Subfamily.N5_RR.PD | 894-1369 | 46 | 8.70000000001e-130 | 422.7 | In-house | 1-265 (265) | Show / Hide |
Range on Protein: 894-1369 Range on HMM: 1-265/265 Sequence Identity: 46% (199 aa) DLHKEFWDLPLNH-QEKPMVFGSQTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtaSEDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEF ||.|||..||||. ||...||||||||||||||||||||||||||||| .||..|||||||||.|..||.||||||||||||..| dlekeflelPlnfsqeelevfgsqtknryktilPnensrvllesesse----------------dedssyinanyikGydeeskayvatqGPlpntiadf WLMIYqntqryirrcvdggssssphvdreqilQQYFQKIVMLTNFTEANRQKCAVYFPielneifavaakcevfqlsaaardyfdryltptfvpdtvvas |.||| |...|.|||||...||||||||||||||.|||||.|...|| ||... Wrmiy---------------------------qeevqvivmltklkeanrqkcavyfP------------------------------------------ sDAIDYEISGRHIGVEsvkvtlegdllealpaqgsfflIKNVGIVRRNGYSVRKLVLLYCIRVPQSasyhlqkiyCYHYWYPDWPDHHSPRDINTLLDTC ||.||.||||||||.|..||..|..||||.|||||.||.|||||||..|.| ...|.|.||.|| |. |.||| -daedyeiserygdve----------------------ikveeiverndysvrklvlkylervers---------vkhywytdWPdhksPddintlldlv LHVlnlgkcesefdiyDDTRSERNAHLAaqrleiyqqdifnavqPLpVIHCSAGIGRTGCFTAILNAVRQLRQslaysltgmltksltsssteeyhnptd |||||||||.||..||||||. .|.||||.|||||| lev-------------eesreeenakla----------------Pv-vvhcsaGiGrtGcfiaisiavrqlre--------------------------- sdssftcntirhishildhrdaeavktppsfdrlpkmpDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLK |.||||||.||||||||||.||||| --------------------------------------eivvdvlkivcnlrldrGGmvqtseqyelihralclylk |
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| Phosphatase | PTP-ER.AA | PTPc | 894-1369 | 17 | 8.1e-47 | 162.77 | SMART | 1-308 (308) | Show / Hide |
Range on Protein: 894-1369
Range on HMM: 1-308/308
Sequence Identity: 17% (93 aa)
DLHKEFWDLPLNHQEK---------PMVFGSQTK------NRYK-TILPNENSRVLLESESSELTSLLGEIKRTSSVTASEDLPYINANYIKGPDYVSKC
. .|| .|. . ... .. . . |||| |.... .|| | .. .| |. |||||||.|. . .|
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGES-------------HCYEGSDYINANYIDGY-WRPKR
YVATQGPLPNTIFEFWLMIYQNTQRYIRRCVDGGSSSSPHVDREQILQQYFQKIVMLTNFTEA--------NRQKCAVYFPIELNEIFAVAAKCEVFQLS
| .||||||.|| || |..|. . ||||.|. | .| ||. |.| | . . . .| .|
YICTQGPLPHTIEDFWRMVWQQ---------------------------KCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE-PMTYG---HITVTCKS
AAARDYFDRYLTPTFVPDTVVASSDAIDYEISGRHIGVESVKVTLEGDLLEALPAQGSFFLIKNVGIVRRNGYSVRKLVLLYCIRVPQSASYHL----QK
. ..| .|.. . .. . . | . ..
EEKCP-----------------------------------------------------------------DDYTMRTFEVTNTGCNCK---Y-SMACSET
IYCYHYWYPDWPDHHSP---RDINTLLDTCLHVLNLGKCESEFDIYDDTRSERNAHLAAQRLEIYQQDIFNAVQPL---------------PVIHCSAGI
..||.|..|||| | ... .. .. |. . ..... . .|.|||||.
RTVTHYHYTNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYM-N-------------------------------MVSSNSKYHHTCPTGPIVVHCSAGC
GRTGCFTAILNAVRQLRQSLAYSLTGMLTKSLTSSSTEEYHNPTDSDSSFTCNTIRHISHILDHRDAEAVKTPPSFDRLPKMPDIFVDVLGIVCNLRLQR
||||.| || ...|... ||...||. .| ||
GRTGTFCAIDIMCQQIEN--------------------------------------------------------------------VDIFQIVKMMRNQR
GGMVQNSEQYELIHRAICLYLK
||||. ||| ..|.| |.|
PGMVQTEEQYIFCYRCILEYIK
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| Phosphatase | PTP-ER.AA | PTPc_motif | 1167-1366 | 19 | 6.2e-28 | 100.05 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 1167-1366 Range on HMM: 1-92/92 Sequence Identity: 19% (40 aa) YCYHYWYPDWPDH-----HSPRDINTLLDTCLHVLNLGKCESEFDIYDDTRSERNAHLAAQRLEIYQQDIFNAVQPLPVIHCSAGIGRTGCFTAILNAVR ..||.|..|||| . | . .|. . || . .|.|||||.||||.| || ... TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK----------------------------------------PIVVHCSAGCGRTGTFCAIDMMMQ QLRQSLAYSLTGMLTKSLTSSSTEEYHNPTDSDSSFTCNTIRHISHILDHRDAEAVKTPPSFDRLPKMPDIFVDVLGIVCNLRLQRGGMVQNSEQYELIH | ||....|. .| || ||||. ||| .. Q-----------------------------------------------------------------------VDIFQTVKEMRKQRPGMVQTEEQYIFCY RAICL |.| RCILE |
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| Phosphatase | PTP-ER.AA | Subfamily.N_Choan_2.PD | 909-1070 | 28 | 4.4e-27 | 85.8 | In-house | 15-133 (266) | Show / Hide |
Range on Protein: 909-1070
Range on HMM: 15-133/266
Sequence Identity: 28% (46 aa)
KPMVFGSQTKNRYKTILPNENSRVLLesesseltsllgeikrtSSVTASEDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQryirrcv
| . .. |||. |||. ..|| | .... . ||||||..| | .| |.|..||||.|...||||...
iPeyarnkrlnRyndiLPsPatRvrl-----------------eeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekv-------
dggssssphvdreqilqqyfQKIVMLTNFTEANRQKCAVYFPIELNEIFAV-AAKCEVFQLSA
. |||.|...| .|.||..|.| | .| .. . | .|..||
--------------------taivmttgleEkgrkkCerYWpaepkekvkladgkikvlalse
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| Phosphatase | PTP-ER.AA | Y_phosphatase | 915-999 | 38 | 4.3e-23 | 82.33 | Pfam | 1-68 (243) | Show / Hide |
Range on Protein: 915-999 Range on HMM: 1-68/243 Sequence Identity: 38% (33 aa) SQTKNRYKTILPNENSRVLLESESSELTSLLGEIKRTSSVTASEDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQN . ||||| |......|| | .. || |||||||.||. .| | .||||.|.|| .|| |..|. NKEKNRYKDIPCYDHTRVKLQPI-----------------PGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQ |
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| Phosphatase | PTP-ER.AA | Subfamily.N_Fungi_PTP1.PD | 915-1002 | 36 | 2.6e-18 | 57.0 | In-house | 45-128 (343) | Show / Hide |
Range on Protein: 915-1002 Range on HMM: 45-128/343 Sequence Identity: 36% (34 aa) SQTKNRYKTILPNENSRVLLE-SESSEltsllgeiKRTSSVTASEDlpYINANYIKGP----DYVSKC-YVATQGPLPNTIFEFWLMIYQNTQR . .||||| ||| | ||| |. | | . . ..| ||||||.| . . .. |.|||.|||.|..|. .|..| . lfaknrYknilPYehsrvkLkkslkss--------dakkhslstnD--YinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvk |
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| Phosphatase | PTP-ER.AA | Subfamily.N12.PD | 915-1000 | 38 | 2.6e-17 | 53.8 | In-house | 32-99 (270) | Show / Hide |
Range on Protein: 915-1000 Range on HMM: 32-99/270 Sequence Identity: 38% (33 aa) SQTKNRYKTILPNENSRVLLESESSELtsllgeikrtssvtaseDLPYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNT ..||||| ||| ..||| |. ...| . |||||.|||.. .. |.|.|||||.|. .|| ||.. . nvkknrykDilPydksrvelskieeee-----------------gsdyinanfikgve-gkleyiaaqgPLpktlddfWrmiwekn |
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| Phosphatase | PTP-ER.AA | Subfamily.RB.PD | 915-1004 | 36 | 1.5e-14 | 44.9 | In-house | 26-97 (261) | Show / Hide |
Range on Protein: 915-1004 Range on HMM: 26-97/261 Sequence Identity: 36% (33 aa) SQTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasEDLPYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI ...|||.. ||| ..||| |.. ..| .| |||||||.| . |.|||||||.|. .|| |.... . | nraknrftnilpydhsrvkLaalkde-----------------sdtdyinanyipgyn-spreyiatqGPlpetvddfWrmvwekkssii |
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| Phosphatase | PTP-ER.AA | Subfamily.R_Anemone_2.PD | 915-1003 | 37 | 1.6e-14 | 45.0 | In-house | 27-97 (262) | Show / Hide |
Range on Protein: 915-1003 Range on HMM: 27-97/262 Sequence Identity: 37% (33 aa) SQTKNRYKTILPNENSRVLLESESSELTSllgeikrtssvtaseDlpYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNTQRY ..|||| ||. ...||.|. ..| .| | ||||||| | .| |.|||.|||.|| .|| |... . nkaknryanilaydktrvklqmlegeegs---------------d--yinanyidGyr-rkkayiatqaPlpetiedfWrmvWeqnsav |
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| Phosphatase | PTP-ER.AA | Subfamily.N_Choan_1.PD | 916-1003 | 27 | 5.6e-14 | 43.1 | In-house | 27-96 (262) | Show / Hide |
Range on Protein: 916-1003 Range on HMM: 27-96/262 Sequence Identity: 27% (24 aa) QTKNRYKTILPNENSRVLLESESSELtsllgeikrtssvtaseDLPYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNTQRY ..||||. | ...|| .. .... . |||||...| . | |.|||||.|... .|| |...... vlknrysnivayDatrvkvtpneenk-----------------ntDyinanfvpgyk-gekeyiatqgPvPaslvsfWqmvweqkvsa |
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| Phosphatase | PTP-ER.AA | Subfamily.RC.PD | 915-1002 | 32 | 1.1e-13 | 42.0 | In-house | 26-114 (288) | Show / Hide |
Range on Protein: 915-1002 Range on HMM: 26-114/288 Sequence Identity: 32% (29 aa) SQTKNRYKTILPNENSRVLL--ESESSELTSLLGEIKRTSSVTASEDLPYINANYIKGPdYVSKCYVATQGPLPNTIFEFWLMIYQNTQR ..|||| .|| . || | | | |. . . . . . | |||| .|.. . . |.|.|||| .|. .|| ||... . nksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsy-kkpekyiaaqGplketvddfwrmiferkvk |
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| Phosphatase | PTP-ER.AA | Subfamily.N6.PD | 914-1004 | 34 | 6.7e-13 | 39.5 | In-house | 39-125 (295) | Show / Hide |
Range on Protein: 914-1004 Range on HMM: 39-125/295 Sequence Identity: 34% (34 aa) GSQTKNRYKTILPNENSRVLLESESSELTsllGeikrtssvtaSEdlpYINANYI------------KGPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQ ..||||| ||| ...|| |. .... | |. ||||||| .. . | |.||||.|..|. .|||..|. | | enkeknryknilPfDhtrvilkdgepsvp---g----------sd---YiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdFWrmvwqens RYI rvi |
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| Phosphatase | PTP-ER.AA | Subfamily.RG.PD | 915-1001 | 36 | 7.6e-13 | 39.4 | In-house | 27-95 (264) | Show / Hide |
Range on Protein: 915-1001 Range on HMM: 27-95/264 Sequence Identity: 36% (31 aa) SQTKNRYKTILPNENSRVLLESESseltsllGEiKRTssvtasedlPYINANYIKGPdYVSKCYVATQGPLPNTIFEFWLMIYQNTQ ...|||. |.. |.||| |.. . |. . . ||||.||.| . || |..|||||..|| .|| ||... nkeknReinivaversRvklsplp-------gk-dgk---------DYinAsyidGy-rrskeyivtqgplketiedFWrmiWehna |
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| Phosphatase | PTP-ER.AA | Subfamily.R_Sponge_2.PD | 916-1003 | 36 | 1.4e-12 | 38.6 | In-house | 26-94 (262) | Show / Hide |
Range on Protein: 916-1003 Range on HMM: 26-94/262 Sequence Identity: 36% (30 aa) QTKNRYKTILPNENSRVLLESEsseltsllgeikrtssvtASEDLPYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNTQRY ..|||.| ||| ..||| |... .|.| ||||... | |.|.||||||..|. .|| |... vgKnRfkeilpydmsRvrLrtd------------------gskdsDYinAsfvdgyk-rrkayiatqgPlketveDfWRmvweykvst |
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| Phosphatase | PTP-ER.AA | Subfamily.N13.PD | 916-1003 | 31 | 3.9e-12 | 37.2 | In-house | 27-93 (259) | Show / Hide |
Range on Protein: 916-1003 Range on HMM: 27-93/259 Sequence Identity: 31% (28 aa) QTKNRYKTILPNENSRVLLESESSeltsllgeikrtssvtasedlpYINANYIKGP-DYVSKCYVATQGPLPNTIFEFWLMIYQNTQRY ..||||. .|| ...|| |..|.. ||||..|| | . |.|.|||||.|. .||.|... . . kdknryrnvlPydetrvklgdegg----------------------yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaev |
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| Phosphatase | PTP-ER.AA | Subfamily.N6.PD | 1024-1266 | 30 | 6e-12 | 36.4 | In-house | 118-254 (295) | Show / Hide |
Range on Protein: 1024-1266
Range on HMM: 118-254/295
Sequence Identity: 30% (45 aa)
LQQYFQKIVMLTNFTEANRQKCAVYFPIELNEIFavAAKCEVFQLSAAARDyfdryltptfvpdtvvassdaidyeisgrhigvesvkvtlegdllealp
|. . |||.|. .| ...||| |.| | .. . .| ..| . .| .|.... ..| . ..| . |||| |.| ...|.
wqensrvivmttkevergknkCarYWPdeetkke--tGvitvtsisEksta-------------------------------------------------
aqgsffliknvgivrrnGYSVRKLVLLYCiRVPQSAsyhlqkIYCYHYWYPDWPDHHSPRDINTLLDTCLHVlNlgKCESEFdiyddtrsernahlaaqr
.| | | ..|.. |. |.|||||||||| | | .....||
-----------------dYtlRefsvshk-dkdkea------reifqyhfkaWPdhgvpkdpgvvlnfledv-n--kkqeel------------------
leiyqqdifNAVQPLpVIHCSAGIGRTGCFTAILNAVRQLRQS
---------ekagpi-vvhcsaGiGrtGtfividivlkiieqs
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| Phosphatase | PTP-ER.AA | Subfamily.N9.PD | 915-1002 | 31 | 8.7e-12 | 36.0 | In-house | 26-95 (275) | Show / Hide |
Range on Protein: 915-1002 Range on HMM: 26-95/275 Sequence Identity: 31% (27 aa) SQTKNRYKTILPNENSRVLLESESSEltsllgeikrT-SsvtaseDlpYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNTQR .||||. .| ...|| |.... . . | | |||||...| |...||||||..|. .||.|.... . nleknrytdvlcydetrvklaklded----------eas------d--yinanfvdGyk-qkkafiatqGplkktvsdfwrmvweqevl |
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| Phosphatase | PTP-ER.AA | Subfamily.R_Ecdysozoa.PD | 916-1000 | 32 | 3.8e-11 | 33.6 | In-house | 28-94 (269) | Show / Hide |
Range on Protein: 916-1000 Range on HMM: 28-94/269 Sequence Identity: 32% (27 aa) QTKNRYKTILPNENSRVLLESesseltsllgeikrtssVTASEDLPYINANYIKGPDYvSKCYVATQGPLPNTIFEFWLMIYQNT . ||||. | . .. || |. ....|| ||||..||| . .| ..| |.|. .||..|| || . alknryedikafDktrvkLkk-----------------ingkedsdyinasfikgyke-kkkfiaaqdPveatigDfWrmiaeqe |
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| Phosphatase | PTP-ER.AA | Subfamily.R_Anemone_1.PD | 915-1002 | 33 | 6e-11 | 33.4 | In-house | 25-94 (258) | Show / Hide |
Range on Protein: 915-1002 Range on HMM: 25-94/258 Sequence Identity: 33% (28 aa) SQTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasEDLPYINANYIKGPDYVsKCYVATQGPLPNTIFEFWLMIYQNTQR ..||||. |.. ..|||.||..|.. |. |||| |... | . ..|||.||..|. .|| |.|. nkkknryadivaldhsRvvLeklsnd-----------------eesdYinasylrasdkt-rafiatqapleetvedFWrmvwqekig |
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| Phosphatase | PTP-ER.AA | Subfamily.N23.PD | 957-1003 | 36 | 7e-11 | 32.6 | In-house | 128-174 (350) | Show / Hide |
Range on Protein: 957-1003 Range on HMM: 128-174/350 Sequence Identity: 36% (17 aa) SEDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQRY .. |||| |.| .| ...|||||...|. .||||.... . gqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssv |
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| Phosphatase | PTP-ER.AA | Y_phosphatase | 1164-1266 | 24 | 7.1e-11 | 39.33 | Pfam | 135-208 (243) | Show / Hide |
Range on Protein: 1164-1266 Range on HMM: 135-208/243 Sequence Identity: 24% (26 aa) QKIYCYHYWYPDWPDHHSPRD-INTLLDTCLHVLNLGKCESEFDIYDDTRSERNAHLAAQRLEIYQQDIFNAVQPLP-VIHCSAGIGRTGCFTAILNAVR .. ..||.|..|||| | . . .|| | . . .... . .| |.|||||.||||.| || . . ETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP---------NPDHGC----------------------PPIVVHCSAGCGRTGTFCAIDIMCQ QLRQS |.... QMEHE |
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| Phosphatase | PTP-ER.AA | Y_phosphatase | 1334-1366 | 45 | 9.4e-11 | 38.91 | Pfam | 211-243 (243) | Show / Hide |
Range on Protein: 1334-1366 Range on HMM: 211-243/243 Sequence Identity: 45% (15 aa) VDVLGIVCNLRLQRGGMVQNSEQYELIHRAICL ||...||. .| || ||||. |||. ....| VDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE |
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| Phosphatase | PTP-ER.AA | Subfamily.N_Nematode_egg.PD | 892-1050 | 20 | 1.3e-10 | 32.0 | In-house | 6-114 (257) | Show / Hide |
Range on Protein: 892-1050 Range on HMM: 6-114/257 Sequence Identity: 20% (32 aa) FRDLHKEFWDLPLNHQEKPmvfGSQTKNRYKTILPNENSRVLLESESSELTSllgeikrtssvtasedlPYINANYIKGPDYVSKcYVATQGPLPNTIFE | |.. . . .|.. . ..| | | . .| ||| || . . .| ||..||. . .. .| || || .|| feilersvdeislttaasd---nylekarskrvhckessrvklelrrGqyld-----------------dfihanrvkGkpllne-filaqaplkntved FWLMIYQNTQRYIRRCVDGGSSssphvdreqilqqyfqkivmltnfteanrQKCAVYFP |..|. .|| | ..| |.| fwrmvfqekvqyivmltsakes-----------------------------erceyywp |
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| Phosphatase | PTP-ER.AA | Subfamily.N_Nematode_4.PD | 958-1004 | 36 | 2.2e-10 | 31.3 | In-house | 50-94 (264) | Show / Hide |
Range on Protein: 958-1004 Range on HMM: 50-94/264 Sequence Identity: 36% (17 aa) EDLPYINANYIKGPDYVSkcYVATQGPLPNTIFEFWLMIYQNTQRYI | || |.... || |..|||||..|. .|| |.|.. .. pdndyihaswmrmPdkfr--yistqGPlketlsdfwhmvytekiavv |
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| Phosphatase | PTP-ER.AA | Subfamily.RA.PD | 916-1000 | 32 | 2.4e-10 | 31.1 | In-house | 28-94 (266) | Show / Hide |
Range on Protein: 916-1000 Range on HMM: 28-94/266 Sequence Identity: 32% (27 aa) QTKNRYKTILPNENSRVLLesesseltsllgeikrtSSVTASEDLPYINANYIKGPDYvSKCYVATQGPLPNTIFEFWLMIYQNT . |||. |||.. ||| | | . |. |||| .|.| . ..|.|||. .|. .|| ||.. kkknrvvqilpydfsrvil-----------------svkeGeeesdyinasfidGyre-kdkfiaaqGpkeetvedfwrmiweqk |
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| Phosphatase | PTP-ER.AA | Subfamily.RK.PD | 957-1000 | 33 | 2.9e-10 | 30.7 | In-house | 53-95 (267) | Show / Hide |
Range on Protein: 957-1000 Range on HMM: 53-95/267 Sequence Identity: 33% (14 aa) SEDLPYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNT .. ||||..| . .. ...|||||..|. .|| ..|.. gdssdyinaalidsyk-rpaafivtqgPlqetvkdfWrlvyden |
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| Phosphatase | PTP-ER.AA | Subfamily.RN.PD | 917-1000 | 37 | 4.1e-10 | 30.2 | In-house | 29-95 (264) | Show / Hide |
Range on Protein: 917-1000 Range on HMM: 29-95/264 Sequence Identity: 37% (31 aa) TKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasEDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNT .|||.|..|| ..||| |..|.|. |. |||| | | . .|.||||||..|| .|| |.... kknrskavlpydhsrvklkeeasa-----------------eksdyinasaildhdprapayiatqgplsstiadfwqmvweqG |
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| Phosphatase | PTP-ER.AA | Subfamily.N3.PD | 1168-1261 | 25 | 6.6e-10 | 29.5 | In-house | 158-218 (261) | Show / Hide |
Range on Protein: 1168-1261 Range on HMM: 158-218/261 Sequence Identity: 25% (23 aa) CYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGkcesefdiyddtrsernahlaaqrleiyqqdifnAVQPLP-VIHCSAGIGRTGCFTAILNAVR .. | .|||| | | . .|. .| .| ... | |.|||||||||| . ..|. ilqlqylaWpdhgvPddsadflefvervrklr----------------------------------sgkeePvvvhCsaGigrtGvlilletala |
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| Phosphatase | PTP-ER.AA | Subfamily.N3.PD | 957-1004 | 41 | 8.7e-10 | 29.1 | In-house | 48-97 (261) | Show / Hide |
Range on Protein: 957-1004 Range on HMM: 48-97/261 Sequence Identity: 41% (21 aa) SEDlPYINANYIK--GPD-YVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI || ||||||.. | ... |.||||||..| .|| |..... . | set-dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstli |
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| Phosphatase | PTP-ER.AA | Subfamily.N_Nematode_1.PD | 958-1003 | 38 | 1.8e-09 | 28.2 | In-house | 50-94 (265) | Show / Hide |
Range on Protein: 958-1003 Range on HMM: 50-94/265 Sequence Identity: 38% (16 aa) EDLPYINANYIKGPDYVsKCYVATQGPLPNTIFEFWLMIYQNTQRY || |||. | | .. .|.|| .|| .|| |..|. . lpsdyihanyvgtptnp-krficaqaPldktiadfwymvlqekvea |
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| Phosphatase | PTP-ER.AA | Subfamily.N23.PD | 1236-1365 | 38 | 2.9e-09 | 27.4 | In-house | 282-346 (350) | Show / Hide |
Range on Protein: 1236-1365
Range on HMM: 282-346/350
Sequence Identity: 38% (23 aa)
QPLpVIHCSAGIGRTGCFTAILNAVRQLRQSLAYSltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdrlpkmpdifvD
.|. ..|||||.|||| |. . |.|.|..... .| .|| || |||...... . .|.
kPi-ilhCsaGvgRtgtfcvvysaireltagngii----------------------------------------------------------------n
VLGIVCNLRLQRGGMVQNSEQYELIHRAIC
iprvvrrlrqqRkymvqkkvilkklyeavl
|
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| Phosphatase | PTP-ER.AA | Subfamily.N_Nematode_5.PD | 914-1000 | 30 | 3e-09 | 27.4 | In-house | 24-88 (258) | Show / Hide |
Range on Protein: 914-1000 Range on HMM: 24-88/258 Sequence Identity: 30% (26 aa) GSQTKNRYKTILPNENSRVllesesseltsllgeikrtssVTASEDLPYINANYIKGPDYVSkCYVATQGPLPNTIFEFWLMIYQNT . .|||.| . ....|| . || ||||..|| .| .. || |||.|. .|| |.||. knlkknrskdvkilDetrV---------------------kltdeddsYinaskiklddlek-kliltQlPlpdteedFWrmvyqek |
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| Phosphatase | PTP-ER.AA | Subfamily.N9.PD | 1169-1266 | 28 | 5.7e-09 | 26.7 | In-house | 160-237 (275) | Show / Hide |
Range on Protein: 1169-1266 Range on HMM: 160-237/275 Sequence Identity: 28% (27 aa) YHYWYPDWPDHHSPRDINTLLDtclhVLnlgkcesefdiyDDTRSERnahlAAQRLEIYQQDIFNAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRQS |. . |||. |.. ..||| || . |... |. |. ... ... .| |.|||||||||| |... ...|.. thfqflswPdyGvPssaaslld----vl------------ekvrekq----alavkelgdeskghlsgPPivvhcsaGiGrtGtfitldiclarleev |
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| Phosphatase | PTP-ER.AA | Subfamily.N_Choan_1.PD | 1221-1266 | 36 | 7.2e-09 | 26.4 | In-house | 179-223 (262) | Show / Hide |
Range on Protein: 1221-1266 Range on HMM: 179-223/262 Sequence Identity: 36% (16 aa) AQRLEIYQQDIFNAVQPLpVIHCSAGIGRTGCFTAILNAVRQLRQS | ...... . .|| |||||||.||||.. |. .|...... efrkavlkatkkktkapl-vihCsaGvGrtGtyialDrlvkaveek |
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| Phosphatase | PTP-ER.AA | Subfamily.R_Nematode_2.PD | 960-1000 | 43 | 1.2e-08 | 25.4 | In-house | 55-93 (261) | Show / Hide |
Range on Protein: 960-1000 Range on HMM: 55-93/261 Sequence Identity: 43% (17 aa) LPyINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNT | | ||.. . | ..|||||| || .|| |. |. vp-ihanwvptag-npkrfiatqgPlentsedfWamviqek |
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| Phosphatase | PTP-ER.AA | Subfamily.RB.PD | 1333-1367 | 40 | 1.9e-08 | 24.9 | In-house | 225-259 (261) | Show / Hide |
Range on Protein: 1333-1367 Range on HMM: 225-259/261 Sequence Identity: 40% (14 aa) FVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLY .|||.|.|..|| .| .||. .|| .||... . yvdvfgvvaelReeRnllvqtekqyifiheclldl |
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| Phosphatase | PTP-ER.AA | Subfamily.R_Nematode_3.PD | 961-1058 | 17 | 2.2e-08 | 24.7 | In-house | 52-131 (267) | Show / Hide |
Range on Protein: 961-1058 Range on HMM: 52-131/267 Sequence Identity: 17% (18 aa) PYINANYIKGPDYVskCYVATQGPLpntifefwlmiyqntQ-----RyirrcvdggssSSPHVDR--EQILQQYFQKIVMLTNFTE---ANRQKCAVYFP ..|.||... |. . . . ||.|. . . . ... | |. ...|||.|.| . .||. |.| dfihAnvvecpngl--klIltqsPq---------------kkdkekk-----------kkstieKfwwmieqekveqvvmlcdfveedgeeeekcseYyp IELNEIFA . ... ekvdgelk |
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| Phosphatase | PTP-ER.AA | Subfamily.N12.PD | 1334-1366 | 48 | 8.5e-08 | 22.5 | In-house | 235-267 (270) | Show / Hide |
Range on Protein: 1334-1366 Range on HMM: 235-267/270 Sequence Identity: 48% (15 aa) VDVLGIVCNLRLQRGGMVQNSEQYELIHRAICL .|| .| .|| || .|| |||||...|. ldvfdlvlelrkqraalvqtkeqyelvykavae |
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| Phosphatase | PTP-ER.AA | Subfamily.N14.PD | 916-1002 | 28 | 9.6e-08 | 22.5 | In-house | 27-96 (275) | Show / Hide |
Range on Protein: 916-1002 Range on HMM: 27-96/275 Sequence Identity: 28% (26 aa) QTKNRYKTILPNENSRVLLESesseltsllgeIKRT--SsvtasedlpYINANYIKGPDY-VSKCYVATQGPLPNTIFEFWLMIYQNTQR . |||.| .|| |..|| | . | . |||| || . .. |...||||..|. .|| |.... . aeknrfkdvlPyednrvelsp-----------tkenstg---------yinassikvsvggkersyivaqgPleltvqdfwqmvweqgvq |
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| Phosphatase | PTP-ER.AA | Subfamily.R_Anemone_2.PD | 1333-1368 | 45 | 1.3e-07 | 22.4 | In-house | 226-261 (262) | Show / Hide |
Range on Protein: 1333-1368 Range on HMM: 226-261/262 Sequence Identity: 45% (16 aa) FVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYL |||...| .|| || ||| .|||.|. .. .| lvdvfqtvkqlreqrnlmvqtkdqyefiydvlleal |
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| Phosphatase | PTP-ER.AA | Subfamily.N_Choan_2.PD | 1237-1266 | 56 | 1.8e-07 | 21.5 | In-house | 200-228 (266) | Show / Hide |
Range on Protein: 1237-1266 Range on HMM: 200-228/266 Sequence Identity: 56% (17 aa) PLpVIHCSAGIGRTGCFTAILNAVRQLRQS || ..|||||.||||.. || ||| | .. Pl-lvHcsaGvgRtGtliaiDiavrlLeet |
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| Phosphatase | PTP-ER.AA | Subfamily.RB.PD | 1239-1266 | 44 | 1.9e-07 | 21.7 | In-house | 196-223 (261) | Show / Hide |
Range on Protein: 1239-1266 Range on HMM: 196-223/261 Sequence Identity: 44% (12 aa) PVIHCSAGIGRTGCFTAILNAVRQLRQS |.|||||.|||| | |. . ....... ivvHCsaGvGRtGtfialdrllqaieen |
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| Phosphatase | PTP-ER.AA | Subfamily.N_Nematode_1.PD | 1167-1266 | 25 | 2.4e-07 | 21.2 | In-house | 164-226 (265) | Show / Hide |
Range on Protein: 1167-1266 Range on HMM: 164-226/265 Sequence Identity: 25% (25 aa) YCYHYWYPDWPDHHSPRDINTLLdtclhvlnlgkcesefdiyddtrsernahlaaqrleiyqqDIFNAVQP--LP-VIHCSAGIGRTGCFTAILNAVRQL || . ||||. | . | ....||.. | |.|||||||||| || . .| .. kvthyqWtdWPdrGvPpadlaal----------------------------------------elleavrgskgPivvhCsaGiGrtGtivaieyildkl RQS leg |
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| Phosphatase | PTP-ER.AA | Subfamily.N_Nematode_5.PD | 1237-1369 | 30 | 2.4e-07 | 21.2 | In-house | 191-258 (258) | Show / Hide |
Range on Protein: 1237-1369
Range on HMM: 191-258/258
Sequence Identity: 30% (20 aa)
PLPVIHCSAGIGRTGCFTAILNAVRQLRQSLAYSltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdrlpkmpdifvdV
. |.....|.||.| | ... |. || . .. |. ..| || |.|... || ...|. |.|
apvvvvsdlGlgRagtflllsvaieqlnngkepn-----------------------------------------------------------------i
LGIVCNLRLQRGGMVQNSEQYELIHRAICLYLK
deilkkirsqRpgavesliqyasvyaavldyik
|
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| Phosphatase | PTP-ER.AA | Subfamily.R_Anemone_1.PD | 1240-1265 | 50 | 2.6e-07 | 21.5 | In-house | 194-219 (258) | Show / Hide |
Range on Protein: 1240-1265 Range on HMM: 194-219/258 Sequence Identity: 50% (13 aa) VIHCSAGIGRTGCFTAILNAVRQLRQ |.|||||.|||| | .| ..|... vvhCsaGvgRtGaflvidamleqakk |
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| Phosphatase | PTP-ER.AA | Subfamily.R_Ecdysozoa.PD | 1334-1366 | 45 | 2.7e-07 | 20.9 | In-house | 234-266 (269) | Show / Hide |
Range on Protein: 1334-1366 Range on HMM: 234-266/269 Sequence Identity: 45% (14 aa) VDVLGIVCNLRLQRGGMVQNSEQYELIHRAICL ||.. .|..|| || .||. |||. ..||. vdifetvkkLrsqrnllvqsleqyvflyralad |
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| Phosphatase | PTP-ER.AA | Subfamily.RB.PD | 1023-1193 | 22 | 3.1e-07 | 21.0 | In-house | 89-181 (261) | Show / Hide |
Range on Protein: 1023-1193 Range on HMM: 89-181/261 Sequence Identity: 22% (23 aa) ILQQYFQKIVMLTNFTEANRQKCAVYFPIELNeifavaakcevfqlsaaardyfdryltptfvpdtvvassdaidyeisgrhigvesvkvtlegdlleal .... . |||||. | ..|| |.| . .| . .. . . . . .|.. . . . | .| . |||| |.. .|||| vwekkssiivmltqlvEkgkekceeYWPadee-------------------------------------------------------------------- PAQGSFFLIKNVGIVRRNGYSVRKLVLlycirvPQSASyhlqKIYCYHYWYPDWPDHHSPRDINTLLDTCL . pvlyGdikvtllaekeldewvirefki------ekgke----krkvrqyhftsWpdhgvPektktlldfvr |
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| Phosphatase | PTP-ER.AA | Subfamily.N20.PD | 958-1009 | 37 | 5.4e-07 | 20.4 | In-house | 47-102 (257) | Show / Hide |
Range on Protein: 958-1009 Range on HMM: 47-102/257 Sequence Identity: 37% (21 aa) EDLPYINANYIKGPDYVS-KCYVATQGPLPNTIFEFWLMIYQNTQRYI---RRCVD . ||||.||. . |.|||||| .|| .|| |. .| | | .. kskdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreie |
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| Phosphatase | PTP-ER.AA | Subfamily.RC.PD | 1334-1366 | 41 | 8e-07 | 19.5 | In-house | 253-285 (288) | Show / Hide |
Range on Protein: 1334-1366 Range on HMM: 253-285/288 Sequence Identity: 41% (13 aa) VDVLGIVCNLRLQRGGMVQNSEQYELIHRAICL ||| ..| .|| .| .||. ||| |.. .. vdvfqvvkklrkarplmvsveeqyillydvlve |
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| Phosphatase | PTP-ER.AA | Subfamily.N_Nematode_6.PD | 1240-1268 | 53 | 1.1e-06 | 19.3 | In-house | 189-217 (253) | Show / Hide |
Range on Protein: 1240-1268 Range on HMM: 189-217/253 Sequence Identity: 53% (14 aa) VIHCSAGIGRTGCFTAILNAVRQLRQSLA |.|||||.|||| .. || ... ||. vvhCsaGvGrtGtlaliliilealrlpdf |
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| Phosphatase | PTP-ER.AA | Subfamily.N_Choan_2.PD | 1334-1368 | 50 | 1.3e-06 | 18.7 | In-house | 231-265 (266) | Show / Hide |
Range on Protein: 1334-1368 Range on HMM: 231-265/266 Sequence Identity: 50% (17 aa) VDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYL |||| |. .|| .| .|| .|||||...|. | vdvlaiieelRkdRmalvqhpeqyellykavveya |
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| Phosphatase | PTP-ER.AA | Subfamily.R_Anemone_2.PD | 1239-1265 | 46 | 1.5e-06 | 18.9 | In-house | 197-223 (262) | Show / Hide |
Range on Protein: 1239-1265 Range on HMM: 197-223/262 Sequence Identity: 46% (12 aa) PVIHCSAGIGRTGCFTAILNAVRQLRQ |.|||||.|||| | |. ...... ivvhcsaGvGrtGvfiavdillerika |
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| Phosphatase | PTP-ER.AA | Subfamily.RA.PD | 1333-1367 | 50 | 1.6e-06 | 18.7 | In-house | 230-264 (266) | Show / Hide |
Range on Protein: 1333-1367 Range on HMM: 230-264/266 Sequence Identity: 50% (17 aa) FVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLY .|| ..| .||||| ||| ||||.|.... | kldvfeavkrlrlqrpqmvqtleqyefiykvlley |
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| Phosphatase | PTP-ER.AA | Subfamily.N12.PD | 1236-1265 | 50 | 1.8e-06 | 18.2 | In-house | 200-228 (270) | Show / Hide |
Range on Protein: 1236-1265 Range on HMM: 200-228/270 Sequence Identity: 50% (15 aa) QPLpVIHCSAGIGRTGCFTAILNAVRQLRQ .|| |.|||||.|||| || . ..|.. aPl-vvhCsaGvGrtGtiiaidyvrellka |
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| Phosphatase | PTP-ER.AA | Subfamily.R_Ecdysozoa.PD | 1023-1198 | 30 | 3.3e-06 | 17.4 | In-house | 90-191 (269) | Show / Hide |
Range on Protein: 1023-1198 Range on HMM: 90-191/269 Sequence Identity: 30% (32 aa) ILQQYFQKIVMLTNFTEANRQkCAVYFPIELNEIFAvAAKCEVFQlSAAARDYFDRYLTPTFVPDTVVassdaidyeisgrhigvesvkvtlegdlleal | .| . ||||.| || ||. || |.||| . . .. . . . || | |. . . ...|. .|. |.| |. | . |. ..||. iaeqevtlivmlsnlteknrk-cakyWpiedevqyg-dilvklvs-eekhsdyiireldvskkkeesv-------------------------------- paqgsffliknvgivrrngysvrklvllycirvpqsasYHLQKIYCYHYwyPDWP-DHHSPRDINTLLDTCLHVLNL .| .| --------------------------------------edsrkvvqysy--tgWksDskvPevargllklieqvrel |
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| Phosphatase | PTP-ER.AA | Subfamily.R_Sponge_2.PD | 1023-1076 | 28 | 4e-06 | 17.4 | In-house | 87-140 (262) | Show / Hide |
Range on Protein: 1023-1076 Range on HMM: 87-140/262 Sequence Identity: 28% (15 aa) ILQQYFQKIVMLTNFTEANRQKCAVYFPIELNEIFAVAAKCEVFQLSAAARDYF .. . ..|||||| .| ...||| |.| . .| . .. ... || vweykvstivmltnleengkekcakYWPekvdeeveygkfkvtlkeeekladyi |
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| Phosphatase | PTP-ER.AA | Subfamily.R_Nematode_2.PD | 1169-1273 | 22 | 7.5e-06 | 16.3 | In-house | 163-230 (261) | Show / Hide |
Range on Protein: 1169-1273
Range on HMM: 163-230/261
Sequence Identity: 22% (24 aa)
YHYWYPDWPDHHSPRDIntlldtclhvlnlgkcesefdiyddtrsernahlaaqrLEIYqqDIFNAV----QPLpVIHCSAGIGRTGCFTAILNAVRQLR
|| | .|||. |. .|.. .....| .|. |.|||||||||. | .. |.. .
thyqyeeWpdrgvPksh--------------------------------------aelf--eLlelvkksekPi-vvhCsaGiGRtmafigteylareve
QSLAYSLTG
.||
adptielte
|
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| Phosphatase | PTP-ER.AA | Subfamily.N13.PD | 1236-1262 | 50 | 8.3e-06 | 16.4 | In-house | 192-217 (259) | Show / Hide |
Range on Protein: 1236-1262 Range on HMM: 192-217/259 Sequence Identity: 50% (12 aa) QPLpVIHCSAGIGRTGCFTAILNAVRQ |. |.||||||||.| . .| .. gPi-vvhcsaGiGrsGvlitidvvlgl |
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| Phosphatase | PTP-ER.AA | Subfamily.N_Nematode_6.PD | 956-1004 | 38 | 9.4e-06 | 16.2 | In-house | 44-91 (253) | Show / Hide |
Range on Protein: 956-1004 Range on HMM: 44-91/253 Sequence Identity: 38% (19 aa) ASEDLPYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI | .. || ||..| .. .. ||.|| .|| ||| || || addedfyihanlvkist-kprrlictqaplegtieefwkmilssgveyi |
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| Phosphatase | PTP-ER.AA | Subfamily.RA.PD | 1240-1262 | 47 | 9.9e-06 | 16.0 | In-house | 202-224 (266) | Show / Hide |
Range on Protein: 1240-1262 Range on HMM: 202-224/266 Sequence Identity: 47% (11 aa) VIHCSAGIGRTGCFTAILNAVRQ |.|||||.|||| | .. . . . vvhcsaGvGrtGtfivldavler |
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| Phosphatase | PTP-ER.AA | Subfamily.R_Sponge_2.PD | 1333-1367 | 41 | 9.9e-06 | 16.1 | In-house | 226-260 (262) | Show / Hide |
Range on Protein: 1333-1367 Range on HMM: 226-260/262 Sequence Identity: 41% (14 aa) FVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLY .|| .. .|| .| |.||. .||. || |. | eidvfevlktlrtkriglvqdaaqYvfihdalley |
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| Phosphatase | PTP-ER.AA | Subfamily.N_Fungi_PTP1.PD | 1237-1256 | 45 | 1e-05 | 15.6 | In-house | 261-280 (343) | Show / Hide |
Range on Protein: 1237-1256 Range on HMM: 261-280/343 Sequence Identity: 45% (9 aa) PLPVIHCSAGIGRTGCFTAI . ..|||||.|||| . .. spilvhCsaGvGrtGtlvtl |
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| Phosphatase | PTP-ER.AA | Subfamily.R_Nematode_3.PD | 1240-1272 | 24 | 1e-05 | 16.0 | In-house | 202-218 (267) | Show / Hide |
Range on Protein: 1240-1272 Range on HMM: 202-218/267 Sequence Identity: 24% (8 aa) VIHCSAGIGRTGCFTAilnavrqlrqslayslT |.|||.||.|.... | . vVHCsdGisRsatlaa----------------i |
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| Phosphatase | PTP-ER.AA | Subfamily.RK.PD | 1240-1260 | 52 | 1e-05 | 15.8 | In-house | 203-223 (267) | Show / Hide |
Range on Protein: 1240-1260 Range on HMM: 203-223/267 Sequence Identity: 52% (11 aa) VIHCSAGIGRTGCFTAILNAV |.||.|| ||.|.| || . vvhClaGaGrsGtfiaidivl |
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