Gene MEG2
MEG2
Species: D.melanogaster
Alias: MEG2
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of MEG2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Sec14_4 | MEG2.AA | SEC14 | 166-316 | 24 | 1.4e-28 | 102.17 | SMART | 1-184 (184) | Show / Hide |
Range on Protein: 166-316 Range on HMM: 1-184/184 Sequence Identity: 24% (45 aa) ELQTGKFTILPAR-------TSSGAAIALFTANRHS----PLSVSHTTTLQGIVYQLDSALQD-------SETQRAGLVFIYDMSGSKYSN---FDYDLS |. .||. .. | | .. .| | || . |... |. .||......| .... |...|.|| |...|. .|... EHECGKHYMPGGRHGTRQGYDKDGRPVYYFRAGRHDPKGMMHSCTMHEFLRYHVYVMEKMCQHCPMCMEKMPGGQCGFHWIFDMKGWSMSHFWSPDWGWY QKILTLLKGGYPARLKKVLIVTAPLW---FKAPFKILRLFVREKLRERVFTVS---------VPQLALHVPRKALPIHLGGTLE .|.. .. ||.||.||.|. .| | |....|. . | .||.||... |. . |. ..... || ..|||.. RKMWQIFQDHYPERLHKVYIINPPWWMFFFWVWWKMIKPFLDEKTREKIHFVGPNKVDDNDWKEELHKYIDPECLPEEWGGTCD |
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| Phosphatase | MEG2.AA | Subfamily.N9.PD | 532-806 | 69 | 4.90000000001e-154 | 502.8 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 532-806 Range on HMM: 1-275/275 Sequence Identity: 69% (190 aa) GLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMT ||.||||||||...|||||....||||.|||||||||||..||.||..|.|| |||||||||||||||.|.|.|||||.||..|||||.|||..|||||| GlskeyadirnepveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmt TRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDT |||.||||.||||||...|||| ||||..|....||..|||.|..||..|.||.|.|.|.|.||.|||||||||||...|..|.|||||||..|. |||. trvvergrlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgde WAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAY ..||..||||||||||||||||||||||||..|||.|||.|.. ||...|.|||.|||.|.||.||.||..|||. skghlsgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleyal |
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| Sec14_4 | MEG2.AA | CRAL_TRIO | 185-314 | 25 | 5.3e-34 | 119.87 | Pfam | 1-145 (145) | Show / Hide |
Range on Protein: 185-314 Range on HMM: 1-145/145 Sequence Identity: 25% (37 aa) IAL---FTANRHSPLSV----SHTTTLQGIVYQLDSALQDSETQ--RAGLVFIYDMSG---SKYSNFDYDLSQKILTLLKGGYPARLKKVLIVTAPLWFK . .. || . . .. . .. .||........ |.| ..|...|.||.| . ..|.||.. ........ || ||....|. || ||. CIYWYHIRPHRHWDKKQFMCCTSEEMIRFLVYMCERMMDYMEPQGKIEGWTVIFDMKGLTMKHMWNMDYSMMKFMIQCFQDHYPERLGRMHIHNAPWWFW APFKILRLFVREKLRERVFTVSV---PQLALHVPRKALPIHLGGT . .||.. | .|.||... .. .| |.|.. || .||| VIWKIIKPFIDPKTREKIHFHKNNWFEELHKHIPPDQLPKEYGGT |
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| Phosphatase | MEG2.AA | PTPc | 532-806 | 36 | 2.2e-133 | 450.31 | SMART | 1-308 (308) | Show / Hide |
Range on Protein: 532-806 Range on HMM: 1-308/308 Sequence Identity: 36% (115 aa) GLIKEYADIRNRAPEG---------TFLHARMRANL--TKNRYT-DVLCYDHSRVVLAHEDGD----EPSDYINANFVDGYKQKNAYISTQGPLPKTSQD |. .|. .... |. .. .|. .| .||||. |..||||.||.| ...|. |.|||||||..|||.....|| |||||| | | GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED FWRMIWEQHCLVIVMTTRVMER--------GRVKCGQYWEPTEESSLEFGDYHVRTISVECNE-DYMVASLELRNIKT--------DEIRNVSHWQFTSW ||||.|.|.| .||| .. ||. ||.|| ||| . ....|...| ..|.| . || . .|..| .. .| | | |...|.| FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE---PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNW PDYGVPSSAMAMLNFLQKVREKQAQL-------VQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMP || |||.|....|.|...||..|... |.... ...... .|||||||||.||||||...||.. ..|. || ..| ..|.||....|.. PDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNS-KYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTE DQYVFCHLALIEYAY .||.||. ...||. EQYIFCYRCILEYIK |
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| Phosphatase | MEG2.AA | Y_phosphatase | 557-803 | 46 | 8e-132 | 449.03 | Pfam | 1-243 (243) | Show / Hide |
Range on Protein: 557-803 Range on HMM: 1-243/243 Sequence Identity: 46% (118 aa) NLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDG-YKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGR-VK-CGQYWEP-TEES |. ||||.|..||||.||.| ...|||.|||||||..|| |....||| ||||.|.| |||||.|.|.| .||| ...||.|| .| | ||| .|. NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ SLEFGDYHVRTISVECNEDYMVASLELRNIKT--DEIRNVSHWQFTSWPDYGVPSS-AMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGI ....||..| ..|.|...||.| .|..| .. .| | | |...|.|||.|||.| ...||.|...||..| . .|.. ||||||||||. PMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP---------NPDHGC-PPIVVHCSAGC GRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIE ||||||...||.. ..|. || || ..|...|.||....|...||.||. ...| GRTGTFCAIDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE |
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| Phosphatase | MEG2.AA | Subfamily.R_Anemone_2.PD | 534-804 | 41 | 3e-88 | 287.0 | In-house | 3-260 (262) | Show / Hide |
Range on Protein: 534-804
Range on HMM: 3-260/262
Sequence Identity: 41% (111 aa)
IKEYADI-RNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTT
.|| . |... |. .| .| .||||...| ||..|| | . .|.| |||||||..|||..|.|||.||.|||.| .|||||.|||.. |||| |.
seeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivmlt
RVMERGRVKCGQYWePtEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGlgdtw
..|||..|. .|| | .. | ..|. .| . .||.. |..... ...| |.| ...||||| |||.|.. .|.....|.. |.. .|
qeeergkakvhryW-P-skgsrsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgag-----
aghprgpPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY
|||||||||.||||.||..|| . |... .. |. .||...|.||.| |||.|.. .|.|.
-------pivvhcsaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvllea
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| Phosphatase | MEG2.AA | Subfamily.RB.PD | 535-803 | 38 | 1.1e-84 | 275.1 | In-house | 4-258 (261) | Show / Hide |
Range on Protein: 535-803 Range on HMM: 4-258/261 Sequence Identity: 38% (103 aa) KEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRV .|| .... . . .|. ..| .|||.| .| |||||| ||. . .. .||||||...||.... ||.||||||.| .|||||.||... .||| |.. eeyeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmltql MERGRVKCGQYWePTEESSLEFGDYHVRTISVECNEDYMVASLELRNikTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQlvqglgdtwag .|.|..|| .|| |..|.. .|| .| .. . ...... ...... .|.|.| ...||||||.|||... ..|.|...|||.. .. vEkgkekceeYW-PadeepvlyGdikvtllaekeldewvirefkiek--gkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiek----------- HPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIE |||||||||.|||||||.|| . ..|. . |. |.| ..|..|.. .| .||.| | .|.. kaskkPivvHCsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclld |
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| Phosphatase | MEG2.AA | Subfamily.R_Sponge_2.PD | 537-804 | 37 | 1.9e-81 | 264.7 | In-house | 6-260 (262) | Show / Hide |
Range on Protein: 537-804 Range on HMM: 6-260/262 Sequence Identity: 37% (101 aa) YADIRNrAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHeDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVME . .... |... |... |..|||....| ||.||| | . || . ||||||.||||||...|||.|||||..| .|||||.||.. ||| | . | eksvek-etefslsiaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnlee RGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKT-DEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQlvqglgdtwagh .|. || .|| ... . |.|...| . | .||.. |.| . |. .. ..|....|..||. .||..|..|.....|...| . ngkekcakYWPekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkk------------ PRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY .. .|.|.||.|.|||||||.||. ..||. .. |. .....|..| . .| .||||.| || || sgnkaitvvCsdgvgrtGtfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalley |
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| Phosphatase | MEG2.AA | Subfamily.N_Choan_1.PD | 532-804 | 36 | 5.4e-80 | 259.8 | In-house | 1-260 (262) | Show / Hide |
Range on Protein: 532-804
Range on HMM: 1-260/262
Sequence Identity: 36% (99 aa)
GLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMT
|.|.||..... . | .. .| .||||... ||..|| ..... .. .||||||||.|||....|| ||||.|.. ..||.|.|||. .|||
GfieeyeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmv
TRVMERGRVKCGQYWePTEESSLEFGDYHVRTISVECNEDYMVASLELrNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQglgdt
|| .| |..|| .|| | |.|.|..||. |...| | .. |. ..| . .. | |.|.. ..|.||| |||......|.| ..|.. . . .
treieagklkChryW-Pdenselklgdvtvkslseeekktyierkfkl-eresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktk-----
waghprgPPIVVHCSAGIGRTGTFITLDICISRLEDVGTA-DIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY
|.|.|||||.|||||.|.|| ....|. .| |.. .|...| .| . .||| | ..|. ..
-------aplvihCsaGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavlda
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| Phosphatase | MEG2.AA | Subfamily.RA.PD | 547-804 | 42 | 2.1e-77 | 251.3 | In-house | 17-264 (266) | Show / Hide |
Range on Protein: 547-804 Range on HMM: 17-264/266 Sequence Identity: 42% (108 aa) GTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYW ... | . .| |||. ..| ||.|||.|.. .| | |||||| |.|||..|. .|..|||. .| .|||||||||.. ||| | . ||..|| ||| eklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativmltelkerkeekcaqyw ePtEESSLEFGDYHVRTISVECNEDYMVASLELR----NIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLvqglgdtwAGHprgpPIV | .| .. .|. .| .. ||| | . .. . . .. | |. . |||||. |||.... ||..|.||...| ||.| |||||||||.||| -p-deGlvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqs--------anh----piv VHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY ||||.|| . |.. . |. ..|...| ||. .| ||.|.. .| || vhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlley |
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| Phosphatase | MEG2.AA | Subfamily.R_Anemone_1.PD | 536-804 | 39 | 6.4e-77 | 249.9 | In-house | 5-256 (258) | Show / Hide |
Range on Protein: 536-804 Range on HMM: 5-256/258 Sequence Identity: 39% (106 aa) EYADIRnRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVM |. .. ...| . || ..| .||||.|.. .||||||| ....|| |||||| .........|.| ||.||..|..|||||.|.... |||| | .. efqrlk-eikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLtnli ERGRVKCGQYWePTeeSSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKqaQLVqglGDTwagh | || ||| |. |. ..|...|. . | ||.. .| | . |. | | | ...||.||| |||.|.|.|....||... .| |.. egekkkchqYw-Pd--stekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqks--sla---gar---- prgpPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY |.|||||||.||||.|. .| . .. . ||. .|..||..|.. .|.||||.|||..|. ----pvvvhCsaGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavlea |
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| Phosphatase | MEG2.AA | Subfamily.N3.PD | 534-798 | 38 | 1.6e-76 | 248.2 | In-house | 3-253 (261) | Show / Hide |
Range on Protein: 534-798
Range on HMM: 3-253/261
Sequence Identity: 38% (104 aa)
IKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDgdEpsDYINANFVD----GYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIV
.... . . |. . .||. .||.|||| |.| ||. || | ... ||||||.|. . .. | ||.|||||.||..|||.|.|||.. .||
laqfeelyrkkpglaisaarkpenlaknryrdilpydatrvklkese--t--dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstliv
MTTRVMERGRVKCGQYWePTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQaqlvqglg
| | ..||||||| ||| |..| .||||...|| . .... |.. | |.. .|.| |.. . |...||| |||... .|.|...||...
mlttlverGrvkChqyW-PetedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklr--------
dtwagHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCH
. . .|.|||||||||||| .|.|..... .| . | ..| ||| .| ..|| |
-----sgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtvsqykfvC
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| Phosphatase | MEG2.AA | Subfamily.RK.PD | 551-804 | 37 | 7.3e-74 | 239.5 | In-house | 23-265 (267) | Show / Hide |
Range on Protein: 551-804 Range on HMM: 23-265/267 Sequence Identity: 37% (96 aa) HARMRANLTKNRYTDVLCYDHSRVVLAHEDGDePSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRV-MERGRVKCGQYWepT | | .|||..|.| ||.|.|.| ||| ||||||...|.||. .|.| |||||..| .||||......| ||| | . .|.|||||.|| |. iakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmlteldvevgrvkClkyW--P EESSLEFGDYHVRTISVECNEDYMVASLELRN--IKTDEIRNVSHWQFTSWPDY-GVPSSAMAMLNFLQKVREKQAQlvqglgdtwA--GhprgpPIVVH .. ..|| .| ...| ..|..| . ... . .||| | ..||..||.| .|| |. ..|.....| ..|.. .| .|||||.|| edtevrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqee---------eeeG-----rivvh CSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY ||.||||..|| . .| |. |. .| ..|.... ... .||.|.. . .|. ClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvilea |
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| Phosphatase | MEG2.AA | Subfamily.RG.PD | 533-804 | 37 | 1.1e-73 | 239.2 | In-house | 2-262 (264) | Show / Hide |
Range on Protein: 533-804 Range on HMM: 2-262/264 Sequence Identity: 37% (96 aa) LIKEYADIRNRAPEG-TFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMT | ... .| . .|. . ... . | .|||..... ...||| |. | . .|||||...|||.....|| |||||..| .||||||||...||| | leeqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivml TRVMERGRVKCGQYWePTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRN--VSHWQFTSWPDYGVPSSAMAMLNFLQKVrekqaqlvqglg . |.|| .. .|| |... .||.....|. .| | ..|.| .. |.|.|.|. .. | ....|.||| |.|.|.. .|.| .|| . . |||||.|| tdldekgrrdedvyW-PkkdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkke------------ dTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY | ||.||.| || . .||. .... ... .||..| . .. .|||| . ||.| -eaankeeaGPivvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydallel |
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| Phosphatase | MEG2.AA | Subfamily.N12.PD | 552-804 | 43 | 1.4e-72 | 235.3 | In-house | 27-268 (270) | Show / Hide |
Range on Protein: 552-804 Range on HMM: 27-268/270 Sequence Identity: 43% (103 aa) ARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEE .. | .|||| |.| ||.|||.| .....| ||||||||. | ..| .||..||||||| .||||||||.. ..|| |..| |. || .|| . | gekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryWpeege SSLEFGDYHVRTISVEC-NEDYMVASLELRNIktDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAqlvqglgdtwaghPRGPPIVVHCSAGIG ..||||...| ... . ..|... .|.... .| |.| ...|.||| |||||| .|.....||| ||.|||||||.||||| |..|. . |.. eelefgefevtleeekavdddflirtLkveaq--kesrkvyqfhytaWPDhgvPssaksllelielvrelqe-------------sedaPlvvhCsaGvG RTGTFITLDICISRLEDVGT---ADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY . |. | ..| ||| .| .||.. . |..|. rtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavael |
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| Phosphatase | MEG2.AA | Subfamily.N5_RR.PD | 553-805 | 37 | 1.5e-71 | 232.1 | In-house | 19-264 (265) | Show / Hide |
Range on Protein: 553-805 Range on HMM: 19-264/265 Sequence Identity: 37% (93 aa) RMRANLTKNRYTDVLCYDHSRVVLAHEDGDEP-SDYINANFVDGYKQ-KNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTE .. . |||||...| ..|||.| .|..... |.|||||.. ||.. ..||..||||||.| .||||||..... ||||.|.. |. | || .|. .| evfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdae ES--SLEFGDYHVRTISVECNEDYMVASLELRNIKTdEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGdtwaghprgpPIVVHCSAG . | ..|| .... .. ..|| | .| |.. . |.| |. .|.||| .| .. ..|.....|.|.. . . |.|.|||||||||||| ||. dyeiserygdveikveeiverndysvrklvlkyler-versvkhywytdWPdhksPddintlldlvleveesreeenakla----------PvvvhcsaG IGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA .|.. .|.. .. |. ..| ..| .| .| .|| . | ||..|. iGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclyl |
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| Phosphatase | MEG2.AA | Subfamily.R_Ecdysozoa.PD | 533-805 | 37 | 5.6e-71 | 230.0 | In-house | 2-268 (269) | Show / Hide |
Range on Protein: 533-805 Range on HMM: 2-268/269 Sequence Identity: 37% (105 aa) LIKEYADIRNR-APEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMT | .|| . .| . . . |. |||| |. .|. ||.|.. |.| ||||||.|. |||.|. .| |.|. | .||||||.||. .||| leeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivml TRVMERGRVkCGQYWePTEeSSLEFGDYHVRTISVECNEDYMVASLELRNIK---TDEIRNVSHWQFTSWP-DYGVPSSAMAMLNFLQKVREKQAQLVQg . . | | | .|| | | ..|| |...| | .||. .|.. ..| .. |.| ...|.|. |. || .| ..|.....||| . . . snlteknrk-cakyW-pie-devqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnkl- LGdtwagHpRgPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA | | ||||||||| ||.|.|..||. . .|. ..|| || |.||||. .| .||||.. ||..| sg-----s-r-sPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyraladys |
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| Phosphatase | MEG2.AA | Subfamily.N_Choan_2.PD | 557-805 | 37 | 1.1e-69 | 225.8 | In-house | 21-265 (266) | Show / Hide |
Range on Protein: 557-805 Range on HMM: 21-265/266 Sequence Identity: 37% (95 aa) NLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQ-KNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLE | . |||.|.| ..||.|.... |. . |||||.| |... |..||...|||| | ..|||||||.. ||||| ..|.|| ||.|| . .. ... nkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvk F--GDYHVRTISVECNEDYMVASLELRNikTDEIRNVSHWQFTSWPDYGVPSSAM------AMLNFLQKVREKQAQLVQGlgdtwaghprgPPIVVHCSA |. .|...| | .| |.. |.|.. .|.|.. |.....||| |||... .|. |..||. ..| .. |..||||||. ladgkikvlalseekeegyiltrlrlek--kgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldka-----------ePllvHcsa GIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA |||||.|..||.. || . .|. .|..| .| .| |.|| . . |..||| GvgRtGtliaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavveya |
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| Phosphatase | MEG2.AA | Subfamily.N13.PD | 535-803 | 37 | 1.3e-69 | 225.8 | In-house | 4-256 (259) | Show / Hide |
Range on Protein: 535-803
Range on HMM: 4-256/259
Sequence Identity: 37% (102 aa)
KEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGdepsdYINANFVDGY--KQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTT
.|. ..|. | | .. ..| .|||| .|| ||..|| | | | ||||... ... || .|||||.| .|||.|.|||..||.| |
eefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg-----yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvt
RVMERGRVKCGQYWEPTEESSLEFGD-YHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQlvQGlgdt
|.|.||| .|| .....| . ..|. . |. ... | .|....... | |.|.| .|..|||.||||||. ...|...||. | . .|
lekekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqtd--ag----
waghprgpPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIE
||||||||||||.|..||.|. . .| |.. .|.|.| || .| |||.|.. |..|
--------PivvhcsaGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykaile
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| Phosphatase | MEG2.AA | Subfamily.N6.PD | 532-804 | 37 | 2.2e-69 | 225.2 | In-house | 13-293 (295) | Show / Hide |
Range on Protein: 532-804 Range on HMM: 13-293/295 Sequence Identity: 37% (109 aa) GLIKEYADIRNRAPEGTF--LHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPS-DYINANFV--------DGYKQK-----NAYISTQGPLPKTSQD |. .|. . ... | .. ... | .|||| ..| .||.||.| . . | ||||||.. .| ... . || |||.|..| .| gfweefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsd FWRMIWEQHCLVIVMTTRVMERGRVKCGQYWePTEESSLEFGDYHVRTISVECNEDYMVASLELRNI-KTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFL ||||.|.. . ||||||. .|||. || .|| |.||.. |.|...|..|| . ..||.. ... . | .| |.. ...|..||| |||... ..|||| FWrmvwqensrvivmttkevergknkCarYW-PdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfl QKVREKQAQLvqglgdtwaghPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGT---ADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY ..|..|| .| . ||||||||||||||||| .|| .. .| |. ||. .....||||. .| .|| | |. | edvnkkqeel-----------ekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqfy |
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| Phosphatase | MEG2.AA | Subfamily.N1.PD | 548-804 | 42 | 4.8e-69 | 224.0 | In-house | 19-266 (268) | Show / Hide |
Range on Protein: 548-804 Range on HMM: 19-266/268 Sequence Identity: 42% (105 aa) TFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGdepsDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWE .|....| ..||| || |||||..| ..| |||||..|. . | || ||||||.| . ||.|.|||.. ..| .|.|....|| ||| | etreaklpenrglnryrdvspydhsrikleradv----dyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywp PTEES-SLEFGD--YHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQaQLVQGLGdtwaghprgpPIVVH |. .|.. . ..|. || | .. ..| |||....|.|.|...|...| |||.|||.| |.|.||.|||| |.. .||.|.||||||||.||. qeeeeaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresg-sLssdvg----------pavih CSAGIGRTGTFITLDICISRLEDVGT---ADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY .| |. ..|. | ||. . ..|..| || ||| | .|..| CsagigrsgtlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiaileg |
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| Phosphatase | MEG2.AA | Subfamily.N14.PD | 534-804 | 34 | 2.9e-64 | 208.1 | In-house | 3-273 (275) | Show / Hide |
Range on Protein: 534-804 Range on HMM: 3-273/275 Sequence Identity: 34% (95 aa) IKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDePSDYINANFVDGY--KQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMT .|| | .. .... |.. | |||. ||| |...|| |. . ..|||| . .. || .||||..| ||||.|.|||..||| |. fteyeripkkredallstaklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivml TRVMERGRVKCGQYWEPT--EESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLG | |. |. .|. . .....||| ..| | .| . .. .|.|. . . | |.| | |.| ||| |||. .|.||..|. . . . teeeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnseve dtwAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY ... . ||..||||||.|||| |. |. |. || . ||. .....| || . .| || | . .||.| ---svkeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvliky |
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| Phosphatase | MEG2.AA | Subfamily.RC.PD | 548-804 | 36 | 3.4e-64 | 208.0 | In-house | 17-286 (288) | Show / Hide |
Range on Protein: 548-804 Range on HMM: 17-286/288 Sequence Identity: 36% (99 aa) TFLHARMRANLTKNRYTDVLCYDHSRVVLAH-------------------EDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVI | || | .||||.||| ||. || | | |..|.|.|||| |.|.||. . ||..|||| .| .||||||.|. || tikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplketvddfwrmiferkvkvi VMTTRVMERGRVKCGQYWeptEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGl || |.. | | || .|| || .|| | . ||.. |||.| | . |.| ..|.|||.. ..| .|...||..| | . vmltelkeGdrekcaeyw---eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkrss- gDTWAGHpRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY .. . |..|||..| .|||.||.|. . || |. . | |.| .|. ... .||.. . .|.|. -eafknf-kstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlvet |
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| Phosphatase | MEG2.AA | Subfamily.RN.PD | 543-803 | 44 | 4.1e-60 | 194.4 | In-house | 13-261 (264) | Show / Hide |
Range on Protein: 543-803 Range on HMM: 13-261/264 Sequence Identity: 44% (111 aa) RAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFV-DGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVK .| . | |. |..|||...|| |||||| | .| .| |||||| .. | .. |||.|||||..| |||.|.||| . |||. ||.| | .| eaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnltrleeegvkq CGQYWePtEESSLEFGDYHVRTISVEC-NEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREkqaqlvqglgdTWAGhpRGPP .|| | .| | .. | |. .| .||.| |. |.|..|.| | |. . | |||. |||.|| ..|.| .||.. | | |||||||.| ||||. ckryw-p-deGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnk-----------syrG--rscp IVVHCSAGIGRTGTFITLDICISRLE-DVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIE .| .|. ..|| | || |.|..| ||. .. ||. |. |..| ivvhcsdGaGrtGvyilidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltavae |
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| Phosphatase | MEG2.AA | Subfamily.N_Nematode_1.PD | 533-804 | 35 | 1.4e-57 | 186.2 | In-house | 2-263 (265) | Show / Hide |
Range on Protein: 533-804
Range on HMM: 2-263/265
Sequence Identity: 35% (100 aa)
LIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEdgDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTT
| .|...... ..| . . . ||||.|| | |..||.||.| ||||| ||.| . . .| .|.|| || .||| |. .. |||
lrdefralkkfndeekvkafkeaqeadknrykdvgcldknrvklaee--plpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlc
RVMERGRVKCGQYWEPTEESSLEFGDYHvRTISVECNE--------DYMVASLELRN-IKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAq
...|.|..|| .|. .|.. ||| . ..|.|| . . .. .|. .. |.||.|.| ||| |||. .|.|..|..||....
kliekgkkkcaeyfpakegeklefkekg-qkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrgskg-
lvqglgdtwaghprgpPIVVHCSAGIGRTGTFITLDICISRL-EDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY
||||||||||||||| .... . .| |. |.|.|||.||.|||| ||.| | |..|
----------------PivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvllny
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| Phosphatase | MEG2.AA | Subfamily.N23.PD | 569-805 | 35 | 7.8e-55 | 177.5 | In-house | 114-349 (350) | Show / Hide |
Range on Protein: 569-805 Range on HMM: 114-349/350 Sequence Identity: 35% (85 aa) YDHSRVVLA-HEDGDEPSDYINANFVDGYKQ-KNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISV |..||.| . . .||||| .. .| ||||...|. ||| |.|||. |||| |. |... || ||| |. . |||..| |.. hdpnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslksl ECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQaqLVQGLGDTwAGHPrGPPIVVHCSAGIGRTGTFITLDICISRLE | .. |.|. ... .|.|.| ..|.|...|||.| .|.||..|.. .| .| .| . | ||..|||||.|||||| . | |. rssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetay--aqqrktet-egeg-gkPiilhCsaGvgRtgtfcvvysairelt -DVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA . | ..| |...| || |..| ... .. | .|.| agngiiniprvvrrlrqqRkymvqkkvilkklyeavleaa |
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| Phosphatase | MEG2.AA | Subfamily.N_Nematode_4.PD | 542-804 | 31 | 1.2e-52 | 170.1 | In-house | 12-262 (264) | Show / Hide |
Range on Protein: 542-804 Range on HMM: 12-262/264 Sequence Identity: 31% (84 aa) NRApEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEpsDYINANFVDGYkQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVK ..| . . . .| ||||.|.|| |..|||| . | |. ||| |... | ||||||||..| .||| |.... .|.|| .| | || gka-ppnvtasaseknsdknryadilcidetrvvlknrdpdn--dyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvek CGQYWEPTEESSLEFGDYHVRTISVECN--EDYMVASLELRNIK-----TDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKqaqlvqglgdtwag .|. ..| . .||.|... . . . | .. ||.. |.. . | | |.|.. |.|| |........ |..| .. caryypeksekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkkk-------------- hPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY |||||||||.||| |.. .|.. |. ... .. | ..|. |..| |..| . |||. -kkekPivvhcsaGvGrtatlvGidyatirirenseievldivrelramrlkavqshlqflfllvvliel |
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| Phosphatase | MEG2.AA | Subfamily.R_Nematode_2.PD | 556-804 | 29 | 1.6e-49 | 159.7 | In-house | 28-259 (261) | Show / Hide |
Range on Protein: 556-804 Range on HMM: 28-259/261 Sequence Identity: 29% (73 aa) ANLTKNRYTDVLCYDHSRVVLAHEDGDEPsdyINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLE .. |.|| || | ....|. .. | | ||.|. .... .|.||||| ||.||| |. ... ||| ....|. .|| .|. ......|.. lpkdkhRypdvPCkpetavevivdgkrvp---ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkld FGDYHVRTISVEC--NEDYMVASLELRNIKT-DEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAqlvqglgdtwaghprgpPIVVHCSAGIGRT | ....| |.| ... .. .|. . . . |.| |.|...|||.||| | . . . |. |... |||||||||||||.. lgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkksek-----------------PivvhCsaGiGRt GTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY ||. . ...| | . .....|..| .||. |. . .|... . mafigteylareveadptieltealkelrehRwkgiqtesqlywltlgalyr |
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| Phosphatase | MEG2.AA | Subfamily.N_Nematode_6.PD | 532-805 | 30 | 4.1e-46 | 148.7 | In-house | 1-252 (253) | Show / Hide |
Range on Protein: 532-805
Range on HMM: 1-252/253
Sequence Identity: 30% (83 aa)
GLIKEYADIRNRAPEGTFlhARMRANLTKNRYTDVLCYDHSRVVLAhedgDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMT
|| ||| | | |.| . . .. ..||||.. |.| .|..|| |.. || ||.|. .... .| ||.|| .| ..||.|| . |||
glkkeykdspneasesea--taflkfkdrnrytniqCcdagrlkla----ddedfyihanlvkistkprrlictqaplegtieefwkmilssgveyivml
TRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYM-VASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAqlvqglgd
..|.|. |. .| . . .... . . . | . | || ..|| | | .. .|||.||| | .. | .|. |....
celvekgkeksaeylsdkvGdarkitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvkkdkk--------
twaghprgpPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA
|||||||||.|||||.. . | . | . ... . |.|.|. ..|. ||.. . ..||
---------PivvhCsaGvGrtGtlaliliilealrlpdfqgvkdllvklreerfravqtevqylyalrcvleyl
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| Phosphatase | MEG2.AA | Subfamily.N20.PD | 535-802 | 32 | 9.7e-43 | 137.8 | In-house | 4-253 (257) | Show / Hide |
Range on Protein: 535-802
Range on HMM: 4-253/257
Sequence Identity: 32% (87 aa)
KEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEdgdepSDYINANFVDGY--KQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTT
.|. . . | | .| |||| |.| || .|| | . |||||... .. ||.||||| | .|||.|. |. .|| | ||
qefmalelknlpgefnsgnqpsnreknryrdilpydstrvplgks-----kdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamit
RVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKqaQLVqGlgdtw
.| | .|| .|| . . ||. ..| . . ... ... . | ..| . ||| |||.| |.|| ....... |. .| |
reieggiikcyhywpislkkplelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarks--hlt-g-----
aghprgpPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALI
|.|||||||||||| |. .|. . . . .| | ..| ||. .| .|| ||. ..
-------pmvvhcsagigrtgvflcvdvvfcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcydivl
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| Phosphatase | MEG2.AA | Subfamily.N_Nematode_5.PD | 536-804 | 25 | 7.5e-42 | 134.5 | In-house | 5-256 (258) | Show / Hide |
Range on Protein: 536-804
Range on HMM: 5-256/258
Sequence Identity: 25% (70 aa)
EYADIRNRAPEGTfLHARMRANLTKNRYTDVLCYDHSRVvlahEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVM
|.... . .|. .||.|||..|| ..|..|| . .||...||||. .. . .. .| || |||.|..|||||. .... .|. ..
efeklaslkpnke-tckafeknlkknrskdvkilDetrV----kltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllvede
ERGRVKCgQYWEPTEESSLEFGDYHVRTISVECNEDY-MVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLN-FLQKVREKQAQ-Lvqglgdtw
| . .. ... .... |..|. ... || .|| ..|. . | ... ..| |..||.. .... ..|| .|. .
elketav-sffpletgdylnlgkmfinnrkvevkedekkeytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgkn--------
aghprgPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY
.|.||....|.||.|||..|.. | |.. . .| ...||||||. .... .||.. . |...|
------apvvvvsdlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaavldy
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| Phosphatase | MEG2.AA | PTPc_motif | 689-803 | 35 | 1.5e-40 | 141.91 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 689-803 Range on HMM: 1-92/92 Sequence Identity: 35% (42 aa) NVSHWQFTSWPDY-----GVPSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQ | | ..|.||| |||. ..| |...||. |||||||||.||||||...|..... || .||...|.| TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK--------------------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQ RAYSIQMPDQYVFCHLALIE |. ..|. .||.||. ...| RPGMVQTEEQYIFCYRCILE |
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| Phosphatase | MEG2.AA | Subfamily.N_Nematode_egg.PD | 533-802 | 25 | 6.6e-36 | 115.3 | In-house | 2-253 (257) | Show / Hide |
Range on Protein: 533-802
Range on HMM: 2-253/257
Sequence Identity: 25% (69 aa)
LIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTT
| ... . . | .. .| .|.| | | | . ||| | . | |.| ||.|.| | .| .| || | .|||||...... ||| |
lerrfeilersvdeislttaasdnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmlt
RVMERgrVKCGQYWEPTEESSLEF--GDYHVRTISVECNEDYMVASLELRNIKT-DEIRNVSHWQFtswpDYGVPSSAMAMLNFLQKVREKQAqlvqglg
.| .| || .|. || . | ... .. |. . | . .|. . . || . . ||| |. | |. |.|.|.
sakes--erceyywpkaeseslvtvpGslrienlkvdskadplfrvtklklvGgddeelflehwqg----dvnylsdvysplrvlrklrnlsk-------
dtwaghprgpPIVVHCSAGIGRTGTFITLDICISRLED--VGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALI
|.||.. |. ...|.....| . .| . .. .| .| .| .|.. . .|.| . ..
----------pvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvl
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| Phosphatase | MEG2.AA | Subfamily.R_Nematode_3.PD | 553-723 | 21 | 7e-27 | 85.6 | In-house | 19-200 (267) | Show / Hide |
Range on Protein: 553-723 Range on HMM: 19-200/267 Sequence Identity: 21% (40 aa) RMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDgYKQKNAYISTQGPL--------PKTSQDFWRMIWEQHCLVIVMTTRVME---RGRVK .. ......|...|... ..|||| .|.|.||.| .... | ||.|. .| . || || ... ..||. ..| .. | slskkvsedrrvevpllektrvvLkgygkrfkddfihAnvve-cpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeeek CGQYWEPTEESSLEFGDYHVRT--ISVECNEDYMVASLELrNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQ | .|. .. .|.|... |.. |. | .|| .|.. ... . |.| ....|.. ..| ...|. ...|.. ... cseYypekvdgelkfegvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfveksktp |
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| Phosphatase | MEG2.AA | Subfamily.N_Fungi_PTP1.PD | 558-650 | 33 | 2.1e-25 | 80.6 | In-house | 46-152 (343) | Show / Hide |
Range on Protein: 558-650 Range on HMM: 46-152/343 Sequence Identity: 33% (36 aa) LTKNRYTDVLCYDHSRVVLA--------HEDGDEPSDYINANFVDGY----KQKNA--YISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCG .||||...| |.|||| | . ...||||||.. ... ||.||.|||.| .||...| . . ||.. | .| .. || . faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy QYWEPTE ||. . rYWqegs |
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| Phosphatase | MEG2.AA | Subfamily.N_Nematode_eak.PD | 555-804 | 20 | 1.5e-19 | 61.5 | In-house | 24-279 (281) | Show / Hide |
Range on Protein: 555-804 Range on HMM: 24-279/281 Sequence Identity: 20% (52 aa) RANLTKNRYTDVLCYDHSRVVLAHEDgDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWePTEESSL .. .|| ... .|. | |. .. |||| .. . . || | . . ||.|. ||. ||. .|. | .|. | . |..| leavnrnrvvkivpqdrylvrltssq-lnrdGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyf-pdktevl EFGDYHVRTISVECNEDYM-VASLELRniKTDEIRNVSHWQFTSWPDYGVPSS--AMAMLNFLQKVRE-----KQAQLVQGLGDTWAGHPRGPPIVVHCS ..| . . ... . . |.|| | .| .| |... | .. .| .|. . ...| ...|.. . . | .. .. | kyGildverkeyavkrniletrllilr--kGnethrvlhykvfGwtettlpkyedflalrkvmkevGvlllivmksallrstlkkyihtppsfapiiqsa AGIGRTGTFITLDICISRLEDVGT--ADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY |.|.|. .|. | ... . . . |..|.| .|. .|. | . ....| rGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldy |
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| Phosphatase | MEG2.AA | Subfamily.N_Fungi_PTP1.PD | 686-804 | 31 | 5.6e-17 | 52.9 | In-house | 211-341 (343) | Show / Hide |
Range on Protein: 686-804 Range on HMM: 211-341/343 Sequence Identity: 31% (42 aa) EIRNVSHWQFTSWPDYGVPSSAMAMLNFLQkvrEKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICIS---RLEDVG-----------TA | .| . |. |.| .. .|. |. |. . . .. |..||.||||||.|||||..||| .| ||. | | epyevyqlqvknWkDlslllnPesilqale---vkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktr D-IRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY | .| ..|.|| .| ||..|.. || | DlisiivnelrkqrismvqnldqfifiYeallfy |
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| Phosphatase | MEG2.AA | Subfamily.R_Nematode_3.PD | 740-802 | 31 | 1.3e-12 | 38.8 | In-house | 200-263 (267) | Show / Hide |
Range on Protein: 740-802 Range on HMM: 200-263/267 Sequence Identity: 31% (20 aa) PIVVHCSAGIGRTGTFITLDICISR-LEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALI |.|||||.||.|..|. .. . .. |. |.. ....|.||| || . .. | | .. pvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgil |
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| Phosphatase | MEG2.AA | Subfamily.PTPDC1.PD | 740-796 | 35 | 2.8e-07 | 21.4 | In-house | 168-219 (229) | Show / Hide |
Range on Protein: 740-796 Range on HMM: 168-219/229 Sequence Identity: 35% (20 aa) PIVVHCSAGIGRTGTFITLDICISRleDVgTADirGTVEKIRSQRAYSIQMPDQYVF | ||| || |||| |. . .. .. ||. ....||.|. ||| .| . kiavHCHAGlGRtGvliacylvyak--rl-tae--eaiklvrskrpksiqtreqvel |
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| Phosphatase | MEG2.AA | Family.DSP.PD | 550-757 | 16 | 6.1e-07 | 20.3 | In-house | 120-204 (387) | Show / Hide |
Range on Protein: 550-757
Range on HMM: 120-204/387
Sequence Identity: 16% (18 aa)
LHARMRANLTKNRYTDVLCYDhsrvvlahedgdepsdyinanfvdgykqknayistqgplpktsqdfwrmiweqhclvivmttrvmergrvkcgqywept
|.| . .| ... |.... . .. . .. ...|...|. . . .... . | |.. ..|||
laaknlewlkelgvtkivnlt-------------------------------------------------------------------------------
eesslefgdyhvrtisveC------NedymvaslelrniktdeIRNVSHWQFtSWPDYGVPSSAMAMLNFLQKVREkqaqlvqglgdtwaGHPRGPPIVV
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------------------ddkpqftk-----------------elgikylri-pidDhnapplenlfekaidfiee--------------gndskgvVlV
HCSAGIGRTGTFIT
HCkaGkgRsgtlii
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