Ptp99A
Species: D.melanogaster
Alias: Ptp99A
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: RG
Protein domain

Protein domains of Ptp99A.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Fn3 Ptp99A.AA FN3 171-256 22 2.8e-15 57.99 SMART 1-69 (69) Show / Hide
Range on Protein: 171-256
Range on HMM: 1-69/69
Sequence Identity: 22% (23 aa)

PSKPQN---LTILDVSAN------SITMSWHPPKNQNGAIAGYHVFHIHDNQTGVEIVKNSRNSVETLIHFELQNLRPY----TDYRVIVKAFTT--KNE
|. |.|   |.. ||...      |.| || ||      | ||.                          . . .|.|.    | |.. |.|..   . |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP------IVGYR--------------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGE

G
|
G

Fn3 Ptp99A.AA FN3 271-358 13 2e-06 28.7 SMART 1-69 (69) Show / Hide
Range on Protein: 271-358
Range on HMM: 1-69/69
Sequence Identity: 13% (14 aa)

PSAPAI---VNLTCHSQE------SITIRWRRPYEFYNTIDFYIIKTRLAGQDTHRDIRINASAKELETAMILQNLTTN----SYYEVKVAAATFSVINP
|..|     . .|  .        |.|..| .|      |  |.                           .. .|. .    . ||..|.| . .   .
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP------IVGYR--------------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGE

K
 
G

Phosphatase Ptp99A.AA Subfamily.N6.PD 473-739 39 1e-77 252.6 In-house 11-291 (295) Show / Hide
Range on Protein: 473-739
Range on HMM: 11-291/295
Sequence Identity: 39% (112 aa)

DIGFSREYEAIQNECISDDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHPTPGQKKNLDYINANFI--------DGYQKG-----HAFIGTQGPLPDTF
.||..|.| .|..  .. . .......|||.|||| ||  .||.|| |. .  . .  ||||||.|        .| ...     . .| |||.|.||  
tlgfweefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtv

DCFWRMIWEQRVAIIVMITNLVERGRRKCDMYWPKDGV-ETYGVIQVKLIEEEVMSTYTVRTLQIKHLKLKKKKqcnteKLVYQYHYTNWPDHGTPDHPL
 ||||.|..   .|||.|. ||||. ||  |||. .  ...|||.|. |.|. ...||.|.....| . .|..     . ..|||...|||||.| .|  
sdFWrmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkea-----reifqyhfkaWPdhgvpkdpg

PVLNFVKKSSAAN--PAEAGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNI---VNVFGFLRHIRAQRNFLVQTEEQYIFLHDALV
||||...  . .    .|||||||||||.|||||.||.|..||.|.|. .   ...   ....|.||  |||||.||.|.|.    
vvlnfledvnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavq

Phosphatase Ptp99A.AA PTPc 475-743 39 1.4e-138 467.64 SMART 1-308 (308) Show / Hide
Range on Protein: 475-743
Range on HMM: 1-308/308
Sequence Identity: 39% (124 aa)

GFSREYEAIQNECISD-------DLPCEHSQHPENK--RKNRYL-NITAYDHSRVHLHPTPGQK---KNLDYINANFIDGYQKGHAFIGTQGPLPDTFDC
||..|.| .|.... |       . .|.....|||.  .||||  .| .|||.||.|.|.||..   .. ||||||.|||| .....| ||||||.|.. 
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

FWRMIWEQRVAIIVMITNLVER--------GRRKCDMYWPKDGVETYGVIQVKLIEEEVMS-TYTVRTLQIKHLKLKKK--KQCNTEKLVYQYHYTNWPD
||||.|.|...||||..|..|.        ||.||. ||| .  .||| |.|....||...  ||.||..... . ..|  ..|. .. |..||||||||
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE-PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWPD

HGTPDHPLPVLNFVKKSSAANPAE-------------------AGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQY
||.|..| ..|.|...  . .. .                   .||||||||||.|||||....|.|. ||..   |..|. ....| ||...|||||||
HGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTEEQY

IFLHDALVEAIA
||..... | | 
IFCYRCILEYIK

Phosphatase Ptp99A.AA Y_phosphatase 502-740 44 2.2e-126 430.97 Pfam 1-243 (243) Show / Hide
Range on Protein: 502-740
Range on HMM: 1-243/243
Sequence Identity: 44% (112 aa)

NKRKNRYLNITAYDHSRVHLHPTPGQKKNLDYINANFIDG-YQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIVMITNLVERGR-RK-CDMYWPK---D
||.|||| .| .|||.||.|.|. . ... ||||||.||| |....|.| ||||.|.|.. ||||.|.|....|||..|..|.|| .| |. |||    .
NKEKNRYKDIPCYDHTRVKLQPI-PGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEG

GVETYGVIQVKLIEEEVMSTYTVRTLQIKHLK-LKKKKQCNTEKLVYQYHYTNWPDHGTPDH-PLPVLNFVKKSSAANP-AEAG--PIVVHCSAGVGRTG
. .||| .||....||... |||||..... .       .. .. |..||||||||||.|.. | ..|.|...   ..|  ..|  |||||||||.||||
QPMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQ-----KQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTG

TYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVE
|....|.|. |......|..|....|.|.||...|||||||||......|
TFCAIDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

Phosphatase Ptp99A.AA Subfamily.RG.PD 476-742 50 3.7e-122 398.1 In-house 2-263 (264) Show / Hide
Range on Protein: 476-742
Range on HMM: 2-263/264
Sequence Identity: 50% (136 aa)

FSREYEAIQNEcISDDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHPTPGQKKNlDYINANFIDGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIV
.....|.||.   ..|...|.|...|||.|||..||.|...|||.|.|.||.... |||||..||||.. ...| |||||..|...|||||||....|||
leeqfeeiqkl-kpkdieaesskkeenkeknReinivaversRvklsplpgkdgk-DYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiiv

MITNLVERGRRKCDMYWPK-DGVETYGVIQVKLIEEEVMSTYTVRTLQIKHLKLKKKKQcnteKLVYQYHYTNWPDHGTPDHPLPVLNFVKKSSAANPAE
|.|.|.|.|||..|.|||| |...... ..|.|...|..|.||||....|. | .|.|.    . |.|||||.|||.|.|.. |.||.||||..|||..|
mltdldekgrrdedvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkeke----rvvrqyhytkWPdmgsPestlfvlifvkkeeaankee

AGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEAI
|||||||.||||||.||||.||..|.|......|||...|..|||.|..||.|||||.|..|||.|..
aGPivvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydallelv

Phosphatase Ptp99A.AA Subfamily.R_Anemone_2.PD 476-742 44 1.9e-105 343.4 In-house 2-261 (262) Show / Hide
Range on Protein: 476-742
Range on HMM: 2-261/262
Sequence Identity: 44% (119 aa)

FSREYEAIQNeCISDDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHPTPGQKkNLDYINANFIDGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIV
.|.|||.... . .  . ......| ||.|||| ||.|||..||.|... |.. . ||||||.||||.. .|.| ||.|||.|..||||.|||  |.|||
lseeyerlsr-seetsvtlksalepvnkaknryanilaydktrvklqmlegee-gsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsaviv

MITNLVERGRRKCDMYWPKDGVETYGVIQVKLIEEEVMSTYTVRTLQIKHlklkkkKQCNTEKLVYQYHYTNWPDHGTPDHPLPVLNFVKKSSAAN-PAE
.|...|||..|.. |||..| ..||...|.| ||  .|.|..|....|.      .... |. | |.|||.|||.|.|...  .|..|.....|. ...|
mltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrsfkvkr------teeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesg

AGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEAI
|||||||||||||||..|..|..|..|.. ..|.||......| ||| .|||..||.|..|.|.||. 
agpivvhcsaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvlleal

Phosphatase Ptp99A.AA Subfamily.RB.PD 476-741 45 6e-96 312.1 In-house 2-259 (261) Show / Hide
Range on Protein: 476-741
Range on HMM: 2-259/261
Sequence Identity: 45% (121 aa)

FSREYEAIQNecISDDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHPTPGqKKNLDYINANFIDGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIV
||.||| ...  .. | .........|. |||. ||..||||||.|. .   ... ||||||.|.||.. . .| ||||||.|.| ||||.||... |||
fseeyeelkk--vgkdqavkaaeeavnraknrftnilpydhsrvkLaalkd-esdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiiv

MITNLVERGRRKCDMYWPKDG-VETYGVIQVKLIEEEVMSTYTVRTLQIKHlklkkKKQcntEKLVYQYHYTNWPDHGTPDHPLPVLNFVKKSSAA--NP
|.|.|||.|. ||. |||.|    .|| |.|.|..|. ......|...|..     .|.   .. | |||.| |||||.|... ..|.||..   |  . 
mltqlvEkgkekceeYWPadeepvlyGdikvtllaekeldewvirefkiek-----gke---krkvrqyhftsWpdhgvPektktlldfvrtvreaiekk

AEAGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEA
|...|||||||||||||||.| || .|..|.....|.|||.. ..| .||.|||||.||||.|..|.. 
askkPivvHCsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldl

Phosphatase Ptp99A.AA Subfamily.RA.PD 476-741 42 1.5e-91 297.7 In-house 2-264 (266) Show / Hide
Range on Protein: 476-741
Range on HMM: 2-264/266
Sequence Identity: 42% (114 aa)

FSREYEAIQNECISDDlPCEHSQHPENKRKNRYLNITAYDHSRVHLHPTPGQKkNLDYINANFIDGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIV
.  |.... .  | ..  .. ....|||.|||...|  ||.|||.|    |.. . ||||| |||||.. . || .|||. .| . ||||||||. | ||
leeefkkltsvkiqke-klrtankeenkkknrvvqilpydfsrvilsvkeGee-esdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativ

MITNLVERGRRKCDMYWPKDGVETYGVIQVKLIEEEVMSTYTVRTLQIKhlKLKKKKQCNTEKLVYQYHYTNWPDHGTPDHPLPVLNFVKKSSAANPAEA
|.|.| ||.. ||  |||..|. ||| |.|.. .|.|. .|||| . ..  .| .... ....|| |.|.|.||. | | ..  .|...||  . .. .|
mltelkerkeekcaqywpdeGlvtyGeirvevkdetvledytvrdflvt--qlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsa

G-PIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEA
. |||||||||||||||.|||||.|.... .....||......|.||  .|||.||| |.. .| | 
nhpivvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlley

Phosphatase Ptp99A.AA Subfamily.R_Anemone_1.PD 478-742 42 1.3e-89 291.6 In-house 4-257 (258) Show / Hide
Range on Protein: 478-742
Range on HMM: 4-257/258
Sequence Identity: 42% (113 aa)

REYEAIQnecISDDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHpTPGQKKNLDYINANFIDGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIVMI
|.. ..    ...   | ....|||.|||| .| |.||||| |. .  .... ||||| ......| .||| ||.||..|.. ||||.|......|||.|
aefqrlk---eikeeekevarkaenkkknryadivaldhsRvvLe-klsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmL

TNLVERGRRKCDMYWPKdGVETYGVIQVKLIEEEVMSTYTVRTLQIKhlklkKKKQCnTEKLVYQYHYTNWPDHGTPDHPLPVLNFVKKSSAANPAEAGP
||.|   .||  |||. . |.|| ..|.| ..||.. |..||| ..     |||.  .|. |.|||.|.|||.| |..   ||....|  . . |.| |.
tnliegekkkchqYwPd-stekygelrvslrkkevfadyiirtlvls-----kkket-eerevvqyhftvWpdkgvPqyatavLglrrkvqksslagarp

IVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEAI
||||||||||||...|.||||.|......|..|  .. || .|  .|||.|||.|.| |..||. 
vvvhCsaGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavleal

Phosphatase Ptp99A.AA Subfamily.R_Sponge_2.PD 489-742 40 3.9e-89 289.9 In-house 12-261 (262) Show / Hide
Range on Protein: 489-742
Range on HMM: 12-261/262
Sequence Identity: 40% (102 aa)

SDDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHPtpGQKKNLDYINANFIDGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIVMITNLVERGRRKC
...  .. .. .||. |||. .| .||.|||.|..   ..|. |||||.|.|||.. .|.| |||||..|.. ||||.||..| .|||.|||.|.|. ||
etefslsiaklkenvgKnRfkeilpydmsRvrLrt--dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnleengkekc

DMYWPKD--GVETYGVIQVKLIEEEVMSTYTVRTLQIKHLKLKKKKQCnteklVYQYHYTNWPDHGTPDHPLPVLNFVKKSSA-ANPAEAGPIVVHCSAG
 .|||.   .  .|| ..|.| ||| .. |..|.|.... | .....      | |.|...||.|..|....|...|.     .  . ..|.|.||.|||
akYWPekvdeeveygkfkvtlkeeekladyiirklklskekssegead-----vtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsdg

VGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEAI
||||.|.||..|..... . ..|| .|...| .|..|||...|| |.|||| |.|  
vgrtGtfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalleyi

Phosphatase Ptp99A.AA Subfamily.RK.PD 476-742 36 6.9e-84 272.4 In-house 2-266 (267) Show / Hide
Range on Protein: 476-742
Range on HMM: 2-266/267
Sequence Identity: 36% (98 aa)

FSREYEAIQN-ECISDDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHPTPGQkkNLDYINANFIDGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAII
.  |.|...      .   |. .....|..|||. .| |||.|.| |... |.  . |||||..||.|.. .||| |||||..|   |||...... | |
lkeefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgd--ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasi

VMITNL-VERGRRKCDMYWPKDGVETYGVIQVKLIEEEVMSTYTVRTLQIKHLKlkkkKQCNTEKLVYQYHYTNWPDH-GTPDHPLPVLNFVKKSSAANP
||.|.| ||.|| ||  |||.|.  .|| |.|.|.| |. . . ||......|     .. .  ..| |.....||.. ..|..   .|.....  . ..
vmlteldvevgrvkClkyWPedtevrygdikvelveaeldadlvvrifrvekla----rgqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqe

A-EAGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEAI
  |.|.|||||.|| ||.||.|..| .|. |.....|.||   . .|...  .|.|||||.|..|. .||.
eeeeGrivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvileal

Phosphatase Ptp99A.AA Subfamily.N_Choan_1.PD 475-742 41 9.3e-83 268.9 In-house 1-261 (262) Show / Hide
Range on Protein: 475-742
Range on HMM: 1-261/262
Sequence Identity: 41% (111 aa)

GFSREYEAIQNecISDDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHPTPgQKKNLDYINANFIDGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAII
||  |||....  |  | ... |...||. |||| ||.|||..||...|.  ..|| |||||||..||.. ...| ||||.|....||.|.|||.| .||
Gfieeyeklae--igvdntataskadenvlknrysnivayDatrvkvtpne-enkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsai

VMITNLVERGRRKCDMYWPKDG-VETYGVIQVKLIEEEVMSTYTVRTLQIkhlklkKKKQCNTeKLVYQYHYTNWPDHGTPDHPLPVLNFVKKS-SAANP
|.|. .| |. ||  ||| .    ..| ..|| ..||  .||  |....      ......| . | | .||.||||| |. .  .|.| |.  .| .. 
vmvtreieagklkChryWPdenselklgdvtvkslseeekktyierkfkl------eresget-reveqlaytaWPdhGvPattkellefrkavlkatkk

AEAGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIV-NVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEAI
.  |.|.||||||||||||| || ..|....|. . .|   ....| .||..|||  |||.. |. .|.  
ktkaplvihCsaGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavldal

Phosphatase Ptp99A.AA Subfamily.R_Ecdysozoa.PD 476-741 38 2.6e-82 267.3 In-house 2-267 (269) Show / Hide
Range on Protein: 476-741
Range on HMM: 2-267/269
Sequence Identity: 38% (105 aa)

FSREYEAIQNECiSDDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHPTPGQKkNLDYINANFIDGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIV
. .||| ....    .. .. |.. ||. |||| .|.|.|. || |....|.. . |||||.|| ||.. . ||  |.|.  | .|||||.|| | .|||
leeeyekLearl-eiskstkvsekkenalknryedikafDktrvkLkkingke-dsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtliv

MITNLVERGRRkCDMYWPKDGVETYGVIQVKLIEEEVMSTYTVRTLQIKHLKLKKkkqCNTEKLVYQYHYTNWP-DHGTPDHPLPVLNFVKKSSAANPAE
..|| |  |. |. |||..    || | |||..|| .| |. |.|.. . | .     . .. | ||.||.|. |   |...  .|.....    .  . 
mlsnlteknrk-cakyWpiedevqygdilvklvseekhsdyiireldvskkkees---vedsrkvvqysytgWksDskvPevargllklieqvrelykln

-----AGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEA
     .||||||||||||.|... || .|.|... . |..| . ...| |||.|||  |||.||. ||..  
klsgsrsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyralady

Phosphatase Ptp99A.AA Subfamily.N9.PD 475-740 39 1.3e-80 262.0 In-house 1-272 (275) Show / Hide
Range on Protein: 475-740
Range on HMM: 1-272/275
Sequence Identity: 39% (111 aa)

GFSREYEAIQNECISDDLpcEHSQHPENKRKNRYLNITAYDHSRVHLHPTPGQKKnLDYINANFIDGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAII
| |.||..|.|| ..  .  ..|... | .|||| ..  ||..||.|  ......  |||||||.|||.. .|||.|||||. |.. ||||.|||.| .|
GlskeyadirnepveGtf--lasklranleknrytdvlcydetrvklakldedea-sdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvi

VMITNLVERGRRKCDMYWP--KDGVETYGVIQVKLIEEEVMSTYTVRTLQIKHLKLKKKKQcnteklVYQYHYTNWPDHGTPDHPLPVLNFVKKSS----
||.| .|||||.||  |||  .. .. .| ..|. .| ||.. |.||.|.||. | .....      |  . .. |||.|.|.    .|....|      
vmttrvvergrlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrk------vthfqflswPdyGvPssaaslldvlekvrekqa

---------AANPAEAGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVE
          . ...  |||||||||.|||||.| ||  |....... |.|.  ....|.|| | .||.||| | . |..|
lavkelgdeskghlsgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle

Phosphatase Ptp99A.AA Subfamily.N12.PD 490-741 41 9.6e-80 258.8 In-house 20-268 (270) Show / Hide
Range on Protein: 490-741
Range on HMM: 20-268/270
Sequence Identity: 41% (105 aa)

DDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHPTPGQKkNLDYINANFIDGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIVMITNLVERGRRKCD
.  . |.....||..|||| .|  ||.|||.|. . ... . |||||||| | .. ...| .|||||.| | |||||||..| |.||. ..|||. ||. 
kvysteagekeenvkknrykDilPydksrvelskieeee-gsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCe

MYWPKDGVET--YGVIQVKLIEEEVMS-TYTVRTLQIKHLklkkkkqcNTEKLVYQYHYTNWPDHGTPDHPLPVLNFVKKSSAANPAEAGPIVVHCSAGV
|||. | |.  .| ..|.|.||. ..  ...|||....         .... |||.|||.|||||.|  . ..|.....    ..|. |.||||||||||
ryWpeegeeelefgefevtleeekavdddflirtLkveaq--------kesrkvyqfhytaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGv

GRTGTYIVLDAMLKQIQQKNI---VNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEA
||| |..| . .......|   ..||  . ..| ||. ||||.||| ... |..|   
GrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavael

Phosphatase Ptp99A.AA Subfamily.N5_RR.PD 492-739 36 1.6e-73 238.6 In-house 9-261 (265) Show / Hide
Range on Protein: 492-739
Range on HMM: 9-261/265
Sequence Identity: 36% (96 aa)

LPCEH----SQHPENKRKNRYLNITAYDHSRVHLHPTPGQKKNLDYINANFIDGYQK-GHAFIGTQGPLPDTFDCFWRMIWEQRVAIIVMITNLVERGRR
|| ..     . . ...|||| .|   ..||| |..  .......|||||.| ||..  .|.. |||||| | . |||||....| .|||.|.| |. |.
lPlnfsqeelevfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrq

KCDMYWPKDG-V---ETYGVIQVKLIEEEVMSTYTVRTLQIKHLKLKKKKqcnteklVYQYHYTNWPDHGTPDHPLPVLNFVKK---SSAANPAEAGPIV
|| .|.|..  .   |.|| ...|  |      |.||.| .|.|.  ...       |. | ||.|||| .||.. ..|..|..   |  .. |...|.|
kcavyfPdaedyeiserygdveikveeiverndysvrklvlkylervers-------vkhywytdWPdhksPddintlldlvleveesreeenaklaPvv

VHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALV
||||||.|||| .|  .  ..|......|.|..   ..| .|  .|||.||| ..| ||.
vhcsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralc

Phosphatase Ptp99A.AA Subfamily.N3.PD 490-741 38 1.8e-70 228.4 In-house 14-259 (261) Show / Hide
Range on Protein: 490-741
Range on HMM: 14-259/261
Sequence Identity: 38% (99 aa)

DDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHptpgQKKNlDYINANFIDGYQKG----HAFIGTQGPLPDTFDCFWRMIWEQRVAIIVMITNLVERGR
..| ..... |||  |||| .|..||. ||.|.    . .. ||||||...    .      .| |||||..|   ||.|.|||.. .|||.|.||||||
pglaisaarkpenlaknryrdilpydatrvklk----eset-dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGr

RKCDMYWPKDG-VETYGVIQVKLIEEEVMSTYTVRTLQIKHlklkkkKQCNTEKLVYQYHYTNWPDHGTPDHPLPVLNFVKKSSAANPAEAGPIVVHCSA
 ||  |||. .   ..| ..|.. .|.  ..| .| | .|.      |. . |. ..|  |..||||| ||..  .|.||..  ....  |.|||||||.
vkChqyWPetedelefgefsvrcekedetksyvlrelvlkd------ketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsa

GVGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEA
|||| .|.|.  |  |.... |..   .|..| ||  ||||..|| |. .|...|  
GigrtGvlilletalalieaaepvypldivrtmrdqramlvqtvsqykfvCeailka

Phosphatase Ptp99A.AA Subfamily.RC.PD 493-741 35 8.6e-69 223.2 In-house 17-286 (288) Show / Hide
Range on Protein: 493-741
Range on HMM: 17-286/288
Sequence Identity: 35% (99 aa)

PCEHSQHPENKRKNRYLNITAYDHSRVHL-HP-----------------TPGQKKNLDYINANFIDGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAII
. . ....||| |||| ..  ||. ||.| |                      ..  .|||| |||.|.| . .| .|||| .| | |||||.|..| .|
tikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplketvddfwrmiferkvkvi

VMITNLVERGRRKCDMYWpKDGVETYGVIQVKLIEEEVMSTYTVRTLQIKHlklKKKKQCnteKLVYQYHYTNWPDHGTPDHPLPVLNF---------VK
||.|.| |  | ||  || ..| ..|| ..|.| ...  |.|..| |....   ||.|..   . |.|. ||.|.... |..|  .|..          |
vmltelkeGdrekcaeyw-eeGkrayGdvevdlkdtdkssdyilrklelvn---kkrkds---revtqiqytswsveqlpeepkellkliqvvkqklpqk

KSS-AANPAEAGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEA
.|| | .   ..|..|||..|..|||..| |.|.|. .. .. |.||......| .|  .|..|||||.|.|.||| 
rsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlvet

Phosphatase Ptp99A.AA Subfamily.N13.PD 479-742 34 8.4e-67 216.6 In-house 5-258 (259) Show / Hide
Range on Protein: 479-742
Range on HMM: 5-258/259
Sequence Identity: 34% (92 aa)

EYEAIQNecISDDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHPTPGqkknldYINANFIDG--YQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIVM
|.. ...  .   . || ... |||.|||| |.  ||..||.|    |      ||||..|     .. . .| .|||||.| . ||.|.|||.. .|.|
efkelre--lkpldtcevgkkkenkdknryrnvlPydetrvklgdegg------yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviam

ITNLVERGRRKCDMYWPKDG---VETYGVIQVKLIEEEVMSTYTVRTLQIKHLKLKKKKQcnteklVYQYHYTNWPDHGTPDHPLPVLNFVKKSSAANPa
.|. .|.|. ||. |||.     .  .. ..|.|.. . .....||.|..|... .. ..      | . ....|||||.| .. ....||..    .  
vtlekekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkdsesgesre------vahlnfvkwPdhgvPssaaelvqfvaevrllqt-

EAGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEAI
.|||||||||||.||.|..|..|..|  |.... ..|   .|..| ||. .|||..|||| . |..|..
dagPivvhcsaGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevl

Phosphatase Ptp99A.AA Subfamily.RN.PD 477-741 36 3.1e-62 201.5 In-house 3-262 (264) Show / Hide
Range on Protein: 477-741
Range on HMM: 3-262/264
Sequence Identity: 36% (96 aa)

SREYEAIQNeCISDDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHPTPGqKKNLDYINANFI-DGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIV
..|.||. .   ...  .| .....| .|||. .. .||||||.|. .   ... ||||| .| |   .  |.| |||||..|   ||.|.||||..||.
ekewealca-yeaepstkevakaeknvkknrskavlpydhsrvklkeeas-aeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvviv

MITNLVERGRRKCDMYWPKDGVETYGVIQVKLIEEEVMS-TYTVRTLQIKHLKlkkkkqCNTEKLVYQYHYTNWPDHGTPDHPLPVLNFVKKSSAANPAE
.|.| | | ..|. |||..| |.|.. .|.|. | . .  | ||.. .| |.       .  . | |.|.  ||..|.|  . ..|.| .|   .    .
nltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlq------tsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGr

AGPIVVHCSAGVGRTGTYIVLDAMLKQIQQ-KNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEA
 |||||||.|.||||.||..| .|.....  . ...   | |.| ||. ||.|..|. |   |..|  
scpivvhcsdGaGrtGvyilidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaee

Phosphatase Ptp99A.AA Subfamily.N1.PD 480-742 34 1.9e-61 199.1 In-house 6-267 (268) Show / Hide
Range on Protein: 480-742
Range on HMM: 6-267/268
Sequence Identity: 34% (94 aa)

YEAIQNECISDDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHptpgqKKNLDYINANFIDGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIVMITN
.. |..|  . .|.......|||. .||| ... |||||..|.     ... |||||....  . .. .| ||||||.| | ||.|.|||..|. ..||.
lleidkeskekeletreaklpenrglnryrdvspydhsrikle-----radvdyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnk

LVERGRRKCDMYWPKDGVE---TYGV--IQVKLIEEEVMSTYTVRTLQIKHLKLKKKkqcnteKLVYQYHYTNWPDHGTPDHPLPVLNFVKK--SSAANP
.. ||  |||..  |   ..    ..|||| ||. | ..||.|... |. ..       . ....|||.||| | |. |  .|.|. |  .| .   . |
vvEknqikCaqywpqeeeeaellleetklkvkliseerksyflvrlleLedletqet------reilhfhyttwpdfgvpespaafLkfLfkvresgsLs

AEAGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNI---VNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEAI
|.|.|||||.||.||. ..|..| .|....    |..   | ..| .|  |.|| .|  |   |..| .    
sdvgpavihCsagigrsgtlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiailega

Phosphatase Ptp99A.AA Subfamily.N_Choan_2.PD 500-741 36 1.7e-60 195.7 In-house 19-264 (266) Show / Hide
Range on Protein: 500-741
Range on HMM: 19-264/266
Sequence Identity: 36% (90 aa)

PENKRKNRYLNITAYDHSRVHLHPTpGQKKNLDYINANFIDGYQKGH-AFIGTQGPLPDTFDCFWRMIWEQRVAIIVMITNLVERGRRKCDMYWPKDGVE
||| ||| .|    ..|| |..   ....  |||||.. |... . ..| ..|||| |   |||||||..|  |||.|.|.|.||.||..|||..  |. 
arnkrlnRyndiLPsPatRvrleel-eedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepke

TYGViQVKLIEEEVMSTYTVRTLQIKHLKLKKkkQCNTEKLVyQYHYTNWPDHGTPDHPL------PVLNFVKKSSAA--NPAEAGPIVVHCSAGVGRTG
 . .   |.  ..|.   .   ...|.|.|  . .|..||  ..|..||||| | ..        .|. ....   . ..|.|..|||||||||||| |.
kvkl-adgkikvlalseekeegyiltrlrlek--kgetrrlv-HfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtG

TYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEA
.| ... ..... |.|   ....| .|  |||. ||| .|. |.||     
tliaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavvey

Phosphatase Ptp99A.AA Subfamily.N14.PD 479-742 33 5.4e-58 187.6 In-house 5-274 (275) Show / Hide
Range on Protein: 479-742
Range on HMM: 5-274/275
Sequence Identity: 33% (92 aa)

EYEAIQNECIsdDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHPTpgQKKNLDYINANFIDGYQ--KGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIVM
||| |...    |  .. .. |||..|||. ..  |...||.| ||  .... .||||  |      | . .| .||||. |   ||.|.||||..|||.
eyeripkkre--dallstaklpenaeknrfkdvlPyednrvelspt--kenstgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivm

ITNLVERGRRKCDMYWPKDG----VETYGVIQVKLIEEEVMSTYTVRTLQIKHLKLKKkkqcntEKLVYQYHYTNWPDHGTPDHPLPVLNFVKKS-----
|.  | |. |.  |.||..      ..|  .|     |  .... ..|..|||  |.      |. |.   ||.||||| |. .. |.|...        
lteeeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpske------ertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrr

--SAAN-P--AEAGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEAI
.  . .   .  |..|||||||||||  |. | ... ... . ...   |...| || .||||  || |....|...   
ktnsevesvkeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvlikyl

Phosphatase Ptp99A.AA Subfamily.N_Nematode_1.PD 498-740 32 5.2e-56 181.1 In-house 22-262 (265) Show / Hide
Range on Protein: 498-740
Range on HMM: 22-262/265
Sequence Identity: 32% (80 aa)

QHPENKRKNRYLNITAYDHSRVHLHPTPgqkKNLDYINANFIDGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIVMITNLVERGRRKCDMYWPKDGV
.. ... |||| ...  |..|| |.  |      ||| ||..    . . || .|.|| .| . || |.  ..|  |||. .|.|.|..||  |.|    
keaqeadknrykdvgcldknrvklaeep---lpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlckliekgkkkcaeyfpakeg

ETYGVIQV--K-LIEEEVMSTYTVRTLQ-IKHLKLKKKKQCNTEKLVYQYHYTNWPDHGTPDHPLPVLNFVKKSSaanpAEAGPIVVHCSAGVGRTGTYI
|.  . .   |  .|... .  . .. . ||  .|. .   .... | .|..|.|||.| |   | .|.....      .. ||||||||||.||||| .
eklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavr----gskgPivvhCsaGiGrtGtiv

VLDAMLKQI-QQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVE
... .| .. . |.| ..  ....|| |||. .||. ||.|.|  |..
aieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvlln

Phosphatase Ptp99A.AA Subfamily.N_Nematode_4.PD 494-741 32 3.3e-54 175.2 In-house 18-262 (264) Show / Hide
Range on Protein: 494-741
Range on HMM: 18-262/264
Sequence Identity: 32% (80 aa)

CEHSQHPENKRKNRYLNITAYDHSRVHLHPTPGQKknlDYINANFIDGYqKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIVMITNLVERGRRKCDMYWP
.  |   .|. |||| .|   |..|| |.  . ..   ||| |...     .  .| |||||..| . || |......|..||..|.| | .|| .|.|.
vtasaseknsdknryadilcidetrvvlknrdpdn---dyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryyp

KDGVE--TYGVIQVKLIEEEVMSTYTVRTLQIKHLKLKKKKQCNTEKLVYQY-HYTNWPDHGTPDHPLPVLNFVKKSSAanPAEAGPIVVHCSAGVGRTG
.  .  ..|  ...|.|....    |    .|  . .|||....|.||... ... |.|. .|  .||... |      . . .||||||||||||| |.
eksekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk--kkkekPivvhcsaGvGrta

TYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEA
. .|    .|.... ..|   .|..|| |   ||.. |..||   |.|   
tlvGidyatirirenseievldivrelramrlkavqshlqflfllvvliel

Phosphatase Ptp99A.AA Subfamily.N23.PD 513-741 33 6.8e-53 171.2 In-house 113-348 (350) Show / Hide
Range on Protein: 513-741
Range on HMM: 113-348/350
Sequence Identity: 33% (81 aa)

AYDHSRVHLHPTPGQKKNLDYINANFIDGYQK-GHAFIGTQGPLPDTFDCFWRMIWEQRVAIIVMITNLVERGRRKCDMYWPKDGV--ETYGVIQVKLIE
|..||.|. ....... ||||| ..         || ||||.. |   || |.|||.. .|||.|. ||... ||| |||.|    ...|..| | ... 
rhdpnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslks

EEVMSTYTVRTLQIKHLKLKkkkqcnTEKLVYQYHYTNWPDHGTPDHPLPVLNFVKKSSAAN----PAEA-----GPIVVHCSAGVGRTGTYIVLDAMLK
 ...  |.|...| . .      | .|| . |.|.|...| |. |  .|.|...  .|      .|.      ||..|||||||||||. |. . .....
lrssegwiervlhlqhndvs------tvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysair

QIQQKN-IVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEA
..| |.|.   .|..|.|| . ||..... .| .| .||   
eltagngiiniprvvrrlrqqRkymvqkkvilkklyeavlea

Phosphatase Ptp99A.AA Subfamily.N_Nematode_6.PD 477-740 32 2.7e-46 149.3 In-house 3-250 (253) Show / Hide
Range on Protein: 477-740
Range on HMM: 3-250/253
Sequence Identity: 32% (86 aa)

SREYEAIQNECISDdlpcEHSQHPENKRKNRYLNITAYDHSRVHLHPTPgqkkNLdYINANFIDGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIVM
.||..  ||. ..    | .   ..| .||| ||  .| .|..|   .    .. || ||...  .| . .| ||.|| .| .||.||  . |  |||. 
kkeykdspneases----eataflkfkdrnrytniqCcdagrlkladde----df-yihanlvkistkprrlictqaplegtieefwkmilssgveyivm

ITNLVERGRRKCDMYWPKDgVETYGVIQVKLIEEEVMSTYTVRTLQIKHLKLKKKkqCNTEKLVYQYHYTNWPDHGTPDH---PLPVLNFVKKssaanpa
.|||.|. |.  | ..  |    .|     . ..  .   ..|.   ... |.   . | .|  .|. |||||| ||    .| .|. |||       . 
lcelvekgkeksaeylsdk-vGdarkitklctvikigrkdidkilvrslkrivka--gdeevivkhihWanWPdhGvPdsflsalrllsvvkk-------

EAGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVE
 ||||||||||||||| ...  .|. ... .  .|   | ..| .|   |||| ||.. .  ..|  
dkkPivvhCsaGvGrtGtlaliliilealrlpdfqgvkdllvklreerfravqtevqylyalrcvle

Phosphatase Ptp99A.AA Subfamily.R_Nematode_2.PD 495-739 26 8.6e-46 147.5 In-house 22-257 (261) Show / Hide
Range on Protein: 495-739
Range on HMM: 22-257/261
Sequence Identity: 26% (65 aa)

EHSQHPENKRKNRYLNITAYDHSRVHLHpTPGQKKNldyINANFIDGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIVMITNLVERGRRKCDMYWPK
..|    .| |.|| ..   ....|.   ..|.. .   | ||...  .. . || ||||| .|.. || |.  . |  |||... ||. ..||. |.| 
tesaaylpkdkhRypdvPCkpetavevi-vdgkrvp---ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpl

DGVETY--GVIQVKLIEEEVMSTYTvrtLQIKHLKLKKKKQCNTEKLVYQYHYTNWPDHGTPDHPLPVLNFVKKSSAAnpaeAGPIVVHCSAGVGRTGTY
.  ..   | ...|  ..| . .     .. . || .....  . . |  | |..|||.|.|.  . .. ..    .      |||||||||.|||...|
etsqkldlgrfsiktvsaekilkde---iekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkks----ekPivvhCsaGiGRtmaf

IVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALV
  . . ....... ...   |...| .|   .|||.|. .|. ... 
igteylareveadptieltealkelrehRwkgiqtesqlywltlgal

Phosphatase Ptp99A.AA Subfamily.N20.PD 493-741 35 1.5e-45 147.1 In-house 15-255 (257) Show / Hide
Range on Protein: 493-741
Range on HMM: 15-255/257
Sequence Identity: 35% (90 aa)

PCEH--SQHPENKRKNRYLNITAYDHSRVHLhptpGqkKNLDYINANFIDGYQKGH--AFIGTQGPLPDTFDCFWRMIWEQRVAIIVMITNLVERGRRKC
| |    ..| |. |||| .|  || .|| |    |  |. |||||..|   . |    .| |||||  | | ||.|. |.   .| |||  .| |  ||
pgefnsgnqpsnreknryrdilpydstrvpl----g--kskdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikc

DMYWPKDGVETYGVIQVK--LIEEEVMSTYTVRTLQIkhlklkKKKQCNTEKLVYQYHYTNWPDHGTPDHPLPVLNFVKKssAANPAEAGPIVVHCSAGV
  |||    .   . ...  | . ...  . .| .|.       .|   | . | | ..|.|||||||     ......   | ..||.|||||||.|||
yhywpislkkplelkhfrvflenyqilqyfiirmfqv------vekstgtshsvkqlqftkwpdhgtpasadsfikyiry--arkshltgpmvvhcsagi

GRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEA
| ....| ..  | ..  .|..  . ..| ||. .|||.||| | .| ..|    
grtgvflcvdvvfcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcydivlev

Phosphatase Ptp99A.AA PTPc_motif 639-740 42 4.2e-45 157.07 SMART 1-92 (92) Show / Hide
Range on Protein: 639-740
Range on HMM: 1-92/92
Sequence Identity: 42% (46 aa)

LVYQYHYTNWPDH-----GTPDHPLPVLNFVKKSSAANPAEAGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIF
 |..|||||||||     |.|.   ..| |...  .       |||||||||.|||||....| |. |      |..|......| ||...|||||||||
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQYIF

LHDALVE
..... |
CYRCILE

Phosphatase Ptp99A.AA Subfamily.N_Fungi_PTP1.PD 501-739 28 3.2e-41 132.7 In-house 44-339 (343) Show / Hide
Range on Protein: 501-739
Range on HMM: 44-339/343
Sequence Identity: 28% (81 aa)

ENKRKNRYLNITAYDHSRVHLH----PTPGQK---KNLDYINANFIDGY----QKGHA--FIGTQGPLPDTFDCFWRMIWEQRVAIIVMITNLVERGRRK
|   |||| ||  |.||||.|.    .. ..|   .  ||||||..       .      .| ||.||| |.| |...| .  |.|...|..|| ...||
elfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlek

CDMYWPKDGVETYGViQVKLIEEEVMST--YTVRTLQIKHLKL---KKKKQCNTE---------------KLVYQYHYTNWPDHGTPDHPLPVLNFVK--
. ||.. ... . | ...   |..|..   . .. ..|.      .|........ ||| .. ||.| ..  .|  .|. ..            |  . |
cyrYWqegsydditv-klaskwenimgindsslysadvkkeasdndnksddndlnnnndltpvtaavsepyevyqlqvknWkDlslllnPesilqalevk

--------KSSAANPAEAGPIVVHCSAGVGRTGTYIVLDAMLK------QIQQKN---------IVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALV
.. ||.||||||||||||.. || .|.      .....             ..  . ..| ||  .||. .|.||...||                 
ndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeall

Phosphatase Ptp99A.AA Subfamily.N_Nematode_5.PD 479-739 23 2.2e-39 126.4 In-house 5-254 (258) Show / Hide
Range on Protein: 479-739
Range on HMM: 5-254/258
Sequence Identity: 23% (61 aa)

EYEAIQNECISDDlpcEHSQHPENKRKNRYLNITAYDHSRVhlhptPGQKKNLDYINANFIDGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIVMIT
|.| ... ... .   . ..  .|. |||. ..  .|..||      ..... .||||. |.  .  . .| || |||||   ||||. ..... .|...
efeklaslkpnke---tckafeknlkknrskdvkilDetrV-----kltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllv

NLVERGRRKCDMYW-PKDGVETYGVIQVKLIEEEVMSTYTvRTLQIKHLKlkkkKQCNTEKLVYQYHYTNWPDHGTPDHPLPVLN-FVKKSSAANPAEAG
.  |  .......   ..   ..| . ..  . ||...     .... |     ..|. . ..  ||.|.|...  ||.  .|..  ..| .  . ..  
edeelketavsffpletgdylnlgkmfinnrkvevkedek-keytvevlp----egcsesvfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgkna

PIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALV
|.||....|.||.|| ..|... .|..... .|.   |..|| ||   |..|| ... |..  
pvvvvsdlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaavl

Phosphatase Ptp99A.AA Subfamily.R_Nematode_3.PD 495-735 24 1.1e-34 111.3 In-house 21-259 (267) Show / Hide
Range on Protein: 495-735
Range on HMM: 21-259/267
Sequence Identity: 24% (62 aa)

EhsqhpENKRKNRYLNITAYDHSRVHLHPTpGQKKNLDYINANFIDgYQKGHAFIGTQGPL--------PDTFDCFWRMIWEQRVAIIVMITNLVE---R
.     ..  ..|. ..  . ..|| |.   |.. . |.|.||..   ..|  .| ||.|.         .| . || || ...|...||. . ||   .
s-----kkvsedrrvevpllektrvvLkgy-gkrfkddfihAnvve-cpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedge

GRRKCDMYWPK--DGVETYGVIQVKL--IEEEVMSTYTVRTLQIKHLklkkkkqCNTEKLVYQYHYTNWPDHGTPDHPLPVLNFVKKSSAANpaeaGPIV
. .||  |.|.  ||. . . ..||   |..|.      |||...          . |. |  ..|.|.....|..| ..|. .|.  . .     |.||
eeekcseYypekvdgelkfegvsvkctdikkelsedvekrtlvvtfe-------kkkeftvthllykgWkelnapeepkealelikfveksk----tpvv

VHCSAGVGRTGTYIVLDAMLKQIQQKN-IVNVFGFLRHIRAQRNFLVQTEEQYIFLH
|||.|..|..|  . .     | ...  ...   . ..|.||   .|||....|.  
VHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvi

Phosphatase Ptp99A.AA Subfamily.N_Nematode_egg.PD 476-738 24 8.6e-32 101.8 In-house 2-252 (257) Show / Hide
Range on Protein: 476-738
Range on HMM: 2-252/257
Sequence Identity: 24% (64 aa)

FSREYEAIQNECisDDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHPTPGQKKNlDYINANFIDGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIV
. |..| ...    |. . ...   ... | |   .   . |||.|.   ||  . |.| ||...|      || .| || .| . ||||.....|  ||
lerrfeilersv--deislttaasdnylekarskrvhckessrvklelrrGqyld-dfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyiv

MITNLVERgrRKCDMYWPKDGVETYGVIQVKLI-EEEVMSTYTVRTLQIKHLKLkkkKQCNTEKLVYQYHYTNWPDHGTPDHPLPVLNFVKKSSAanpae
|.|  .|    .|. ||||   |.  ..   |  |   . . .   ... .|||      . |.|  ..   ..   .    || ||  ... |      
mltsakes--erceyywpkaeseslvtvpGslrienlkvdskadplfrvtklkl---vGgddeelflehwqgdvnylsdvysplrvlrklrnlsk-----

agPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIV--NVFGFLRHIRAQRNFLVQTEEQYIFLHDAL
  |.||..  || ...| . ..  | .. .  |.   |      .|.|.. |..  .|.|..  . 
--pvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlv

Phosphatase Ptp99A.AA Subfamily.N23.PD 757-978 24 6.1e-27 85.8 In-house 76-309 (350) Show / Hide
Range on Protein: 757-978
Range on HMM: 76-309/350
Sequence Identity: 24% (58 aa)

LKNCTPYLEQQYKNIIQFQPKDIHIASAMKQVNSIKNRGAifpieGSRVHLT--PKPGEDgSDYINASWLHGFRRL-RDFIVTQHPMAHTIKDFWQMVWD
... ||  | ..     ||. ..  .. .| .  ..| .      .||.|   ..||.  .|||||..|.       .||.|| |.| |. |||.|||. 
npdllpyhlqpttitavpqprhlqtegsGqqqgtpdsrhd-----pnrvklqqstqpgqq-ddyinatylkeltpmsPpfiatqgPiastlaDFWlmvwe

HNAQTVVLLSSLDDI---NFAQFWPD-EATPIESDHYRVKFLNKTNKSDYVSRDFVIQSIQDDYELTVKMLHCPSWPEMSNPNS---IYDFIVDVHERC-
 ....|.| .  .    ...|.||  |  .   ...||   .... . .. |.. .|  . .   .|. ||  .|.|.  |.|. .|. .|..       
qqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslkslrssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetaya

-------NDYRNGPIVIVDRYGGAQACTFCAISSLAIEME
   ..  . ||..    |   . ||| . | ..|..    
qqrktetegeggkPiilhCsaGvgRtgtfcvvysairelt

Phosphatase Ptp99A.AA Subfamily.N_Nematode_eak.PD 496-742 23 1.4e-22 71.6 In-house 20-280 (281) Show / Hide
Range on Protein: 496-742
Range on HMM: 20-280/281
Sequence Identity: 23% (60 aa)

HSQHPENKRKNRYLNITAYDHSRVHLhpTPGQKKNLDYINANFIDGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIVMITNLVERGRRKCDMYWPKD
..  |. ..|| ..|  .|.  |.|  |. |. .. ||||  ..  . |. .| |  .  |    ||.|. ||.   ||... || .  | | |.|... 
vtarleavnrnrvvkivpqdrylvrl--tssqlnrdGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdk

G-VETYGVIQVKLIE----EEVMSTYT--V----RTLQIKHLKLKKKKQCNTEKLV-YQYHYTNWPDHGTPDHPLPVLN----FVKKSSAANPAEAgPIv
|  ||...|.  |    .... |    .     | ...| |.    . .. |.  .   .. |..    .  .    ..||   . |. | || . .. |
tevlkyGildverkeyavkrniletrllilrkGnethrvlhykvfGwtettlpkyedflalrkvmkevGvlllivmksallrstlkkyihtppsfa-pi-

VHCSAGVGRTGTYIVLDAMLKQIQ--QKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEAI
  |.|...|.| ... |.  .||   |  ..  .. .|.| .. |. |....... .        
iqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyl

Phosphatase Ptp99A.AA Family.DSP.PD 619-729 23 4.7e-12 37.1 In-house 129-242 (387) Show / Hide
Range on Protein: 619-729
Range on HMM: 129-242/387
Sequence Identity: 23% (28 aa)

RTLQIKHL-KLKKKKQCNTEKLVYQYHYTNWPDHGTPDHPL---PVLNFVKKssaANpAEAGPIVVHCSAGVGRTGTYIVLDAMLK-QIQQKNIVNVFGF
..|....  .|...|. .|..|  .|.  ...||..|.  .    ...|...   .|  . | ..||| ||.||.|| |.   | . ..  .  ...   
kelgvtkivnltddkpqftkelgikylripidDhnapplenlfekaidfiee---gn-dskgvVlVHCkaGkgRsgtliiaYlmksegltleealdwvrs

LR--HIRAQRNFLVQTEE
|  .|. . .||.| .. 
kRpgvitpnqgflkqlkd

Phosphatase Ptp99A.AA Subfamily.PTPDC1.PD 640-735 28 2.2e-08 25.1 In-house 135-221 (229) Show / Hide
Range on Protein: 640-735
Range on HMM: 135-221/229
Sequence Identity: 28% (27 aa)

VYQYHYtNWPDHGTPDhPLPVLNFVKKSSAANpaEAGPIVVHCSAGVGRTGTYIVLDAMLKQ-IQQKNIvnvfgfLRHIRAQRNFLVQTEEQYIFLH
.| | .  ..|.|..     .|. ||  . |   | | | ||| || ||||  |    . .. .. ..       .. .|..|   .||||  ... 
iyfynf-glkDygvas-leriLdivkvvdfal--eegkiavHCHAGlGRtGvliacylvyakrltaeea------iklvrskrpksiqtreqvelve

Phosphatase Ptp99A.AA Subfamily.CDC14.PD 659-720 33 8.4e-08 23.4 In-house 182-241 (258) Show / Hide
Range on Protein: 659-720
Range on HMM: 182-241/258
Sequence Identity: 33% (20 aa)

PVLNFVKKSSAANPAEAGPIVVHCSAGVGRTGTYIVldAMLKQIQQKNIVNVFGFLRHIRAQ
|  . .||   .     | |.||| ||.||||| |   . | . .. .  .. ..|| .|  
PsdailkkfleitekaeGaiavhCkaGLGrtgtlig--cylikhyrftaaetiawlriarPG

Phosphatase Ptp99A.AA Subfamily.PTEN.PD 598-722 20 1.4e-06 19.1 In-house 17-140 (305) Show / Hide
Range on Protein: 598-722
Range on HMM: 17-140/305
Sequence Identity: 20% (26 aa)

ETYGVIQVKLIEEEVMSTYTVRTLQIKHLKLKKKKQCNTEKLVYQYHYTNWPDHGTPDHPLpVLNFVKKSSAA-NPAEAGPIVVHCSAGVGRTGTYIVLd
|||  .  . ......   ||   . |   |. ... .. ..  . .     ||  |   | . ..|.. .   .  .   ..||| || ||||. |.  
etyekllyrnslddlillltvykgkgklrilnargekedsdfdgrvavypfdDhnpptleL-leeivedvdkwLkedksnVvavHCkaGkGRtGvmica-

AMLKQIQQKNIVNVFGFLRHIRAQRN
 .||. ..|.  .   .  . |.. .
yLlksgikksadealaiydekRtkdk

Phosphatase Ptp99A.AA Subfamily.RG.PD 764-1016 40 2.9e-108 352.5 In-house 2-262 (264) Show / Hide
Range on Protein: 764-1016
Range on HMM: 2-262/264
Sequence Identity: 40% (107 aa)

LEQQYKNIIQFQPKDIHIASAMKQVNSIKNRGA-IFPIEGSRVHLTPKPGEDGSDYINASWLHGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLL
||.|...|....||||...|..|. |. ||| . |...| |||.|.|.||.||.||||||...|.|| ...||||.|...||.|||.|.|.||||..|.|
leeqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivml

SSLDDI---NFAQFWPDEATPIESDHYRVKFLNKTNKSDYVSRDFVIQSIQDDYELT--VKMLHCPSWPEMSNPNSIYDFIVDVH--ERCNDYRNGPIVI
..||.    .....||....|.|.....|..|.|...|.|..||||.....||.|..  |...|...||.|..|.|.......|.  |..|....||||.
tdldekgrrdedvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaankeeaGPivv

VDRYGGAQACTFCAISSLAIEMEYCSTANVYQYAKLYHNKRPGVWTSSEDIRVIYNILSFL
.|..|...|.|..|...|. ..|.....||||..||...||||..|..|....||..|..|
hdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydallel

Phosphatase Ptp99A.AA PTPc 763-1018 26 2.8e-74 254.01 SMART 1-308 (308) Show / Hide
Range on Protein: 763-1018
Range on HMM: 1-308/308
Sequence Identity: 26% (82 aa)

YLEQQYKNIIQFQPKD--------IHIASAMKQVNS--IKNR-G-AIFPIEGSRVHLTPKPGE----DGSDYINASWLHGFRRLRDFIVTQHPMAHTIKD
 ........ ...|.|        . . .| .. |    |||    | ... .||.|.|.|||     |||||||..  |..| . .|.||.|. ||| |
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

FWQMVWDHNAQTVVLLSSLDD-----------INFAQFWPDEATPIESDHYRVKFLNKTNKS-DYVSRDFVIQSIQD--------DYELTVKMLHCPSWP
||.|||... ...| | ....           .  .|.||||  | . .|..|......... ||. |.| ..  ..        ....||. .|...||
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE--PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWP

EMSNP---NSIYDFIVDVHERCNDYRN------------------GPIVIVDRYGGAQACTFCAISSLAIEMEYCSTANVYQYAKLYHNKRPGVWTSSED
... |   .|. ||| .|... . ..|                  ||||..  .|  ...|||||. .   .|     ...|  |   | |||  .. | 
DHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTEEQ

IRVIYNILSFLPG
 . .| .. ..  
YIFCYRCILEYIK

Phosphatase Ptp99A.AA Y_phosphatase 789-1015 31 1.5e-68 238.89 Pfam 1-243 (243) Show / Hide
Range on Protein: 789-1015
Range on HMM: 1-243/243
Sequence Identity: 31% (78 aa)

NSIKNRGA-IFPIEGSRVHLTPKPGEDGSDYINASWLHG-FRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLSSLDDINF-----AQFWPD--EAT
|  |||   | . . .||.|.|.||...||||||..  | ... . .|.||.|| |||.|||.|||... ...| | .... .      .|.|||  | .
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ

PIESDHYRVKFLNKTNKSDYVSRDFVIQSIQD--DYELTVKMLHCPSWPEMSNPNS----IYDFIVDVHERCNDYRNG--PIVIVDRYGGAQACTFCAIS
|.. ....|.  ... ..||. |.| ..  .|  ....||. .|...||. . | |    . |||  |..  .. ..|  |||..   |   ..|||||.
PMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCAID

SLAIEMEYCSTANVYQYAKLYHNKRPGVWTSSEDIRVIYNILSF
 .   ||   | ...|. |   | |||  .. |  . .| ..  
IMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

Phosphatase Ptp99A.AA Subfamily.R_Anemone_2.PD 764-1013 29 2.9e-48 155.9 In-house 2-257 (262) Show / Hide
Range on Protein: 764-1013
Range on HMM: 2-257/262
Sequence Identity: 29% (75 aa)

LEQQYKNIIQFQPKDIHIASAMKQVNSIKNRGA-IFPIEGSRVHLTPKPGEDGSDYINASWLHGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLL
|...|... . . . ... ||...||  ||| | | . . .||.|... || |||||||... |.|| . .| || |...||.|||.|||. |....| |
lseeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivml

SSLDD---INFAQFWPDEAtPIESDHYRVKFLNKTNKSDYVSRDFVIQSIQDDYELTVKMLHCPSWPEMSNPNS---IYDFIVDVHERCNDYRNGPIVIV
. . .   .  ...||..  ... .. .|.  .... |||| | | ..  . . | .|.  |. |||. . |.|   . |.. .|..  ..  .||||. 
tqeeergkakvhryWPskg-srsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpivvh

DRYGGAQACTFCAISSLAIEMEYCSTANVYQYAKLYHNKRPGVWTSSEDIRVIYNIL
   |  .. .|.|...|   ..  .. .|.|. |   ..|. .    ..||..|   
csaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvl

Phosphatase Ptp99A.AA Subfamily.R_Anemone_1.PD 765-1012 25 6.8e-46 148.3 In-house 3-252 (258) Show / Hide
Range on Protein: 765-1012
Range on HMM: 3-252/258
Sequence Identity: 25% (65 aa)

EQQYKNIIqfQPKDIHIASAMKQVNSIKNRG-AIFPIEGSRVHLTPKPGEDGSDYINASWLHGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLS
.......   . |. .  .| |. |  |||   | ... ||| |. . ... |||||||.|..... | ||.||.|. .|..|||.|||.......|.| 
aaefqrlk--eikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLt

SLDD---INFAQFWPDeaTPIESDHYRVKFLNKTNKSDYVSRDFVIQSIQDDYELTVKMLHCPSWPEMSNPN---SIYDFIVDVHERcNDYRNGPIVIVD
.| .    .. |.|||  .. . ...||.  .| ...||..| .|... .   | .|  .|  .||. . |.   .. ..  .|... .   . |.|.  
nliegekkkchqYwPd--stekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqks-slagarpvvvhC

RYGGAQACTFCAISSLAIEMEYCSTANVYQYAKLYHNKRPGVWTSSEDIRVIYNI
  |   . .|..|...   .    . ....| |  ...|| . ...||...    
saGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihla

Phosphatase Ptp99A.AA Subfamily.R_Sponge_2.PD 765-1011 27 2.6e-43 139.6 In-house 3-255 (262) Show / Hide
Range on Protein: 765-1011
Range on HMM: 3-255/262
Sequence Identity: 27% (70 aa)

EQQYKNIIqfQPKDIHIASAMKQVNSIKNRG-AIFPIEGSRVHLTPkPGEDGSDYINASWLHGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLS
|...|..   .......  | .. |  |||   |.| . |||.|.. .|. .|||||||.. |..|  ..|.|| |. .|..||| |||. . .|.|.|.
eeeeksve--ketefslsiaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmlt

SLD---DINFAQFWPDE-ATPIESDHYRVKFLNKTNKSDYVSRDFVIQSIQD-DYELTVKMLHCPSWPEMSNPN---SIYDFIVDVHERCNDYRNGPIVI
 |      . |..||..     |  ...|.. .... .||. |.. ... .  . |..|.  |  .||| . |.   |. ..| .|..  .. .|..|..
nleengkekcakYWPekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitv

VDRYGGAQACTFCAISSLAIEMEYCSTANVYQYAKLYHNKRPGVWTSSEDIRVIYN
| . | ... ||.|. |.   ..  .. .|... |    ||.|.    ..|..   
vCsdgvgrtGtfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihd

Phosphatase Ptp99A.AA Subfamily.RA.PD 765-1013 29 1.1e-42 137.5 In-house 3-261 (266) Show / Hide
Range on Protein: 765-1013
Range on HMM: 3-261/266
Sequence Identity: 29% (76 aa)

EQQYKNIIQFQPKDIHIASAMKQVNSIKNRG-AIFPIEGSRVHLTPKPGEDGSDYINASWLHGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLS
|...|.. . . .. ..  | |. |  |||   |.| . |||.|. | ||. |||||||...|.|.   || .| |...|..|||.|.|.....|.|.|.
eeefkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativmlt

SLDD---INFAQFWPDEATpIESDHYRVKFLNKTNKSDYVSRDFVIQSI----QDDYELTVKMLHCPSWPEMS---NPNSIYDFIVDVHERCNDYRNGPI
 |..      ||.|||| . .   . ||.  ..|   ||  |||... .    ... .  |. .|  ||||.    ..  . ...  |..  . . | ||
elkerkeekcaqywpdeGl-vtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanhpi

VIVDRYGGAQACTFCAISSLAIEMEYCSTANVYQYAKLYHNKRPGVWTSSEDIRVIYNIL
|.    |  .. ||......   ..     .|..  |   ..|| .  . |    ||..|
vvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvl

Phosphatase Ptp99A.AA Subfamily.RK.PD 768-1012 25 2.7e-42 136.0 In-house 6-261 (267) Show / Hide
Range on Protein: 768-1012
Range on HMM: 6-261/267
Sequence Identity: 25% (65 aa)

YK--NIIQFQPKDIHIASAMKQVNSIKNR-GAIFPIEGSRVHLTPKPGEdGSDYINASWLHGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLSS
..  |.. .. .  .. .|.|. |  ||| . | . . |.| |..  |.  ||||||... ...| . |||||.|. .|.||||..|.|.|...|.|. |
fetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmlte

LDDINF----AQFWPDEATpIESDHYRVKFLNKTNKSDYVSRDFVIQSIQD--DYELTVKMLHCPSWPEM----SNPNSIYDFIVDVHERCNDYRNGPIV
|  ..     ..||.... .. .. .|.... . ..|.|.| | .. .    .   .|. ..  .|||      . .|. ..||..  .. ..|.||.  
ldvevgrvkClkyWPedte-vrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeeeeeGriv

IVDRYGGAQACTFCAISSLAIEMEYCSTANVYQYAKLYHNKRPGVWTSSEDIRVIYNI
  |. .. ||.||...   .|  .. .|.. .|   |... .    |  . .|..   
vhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydv

Phosphatase Ptp99A.AA Subfamily.R_Ecdysozoa.PD 764-1013 24 3e-42 135.9 In-house 2-264 (269) Show / Hide
Range on Protein: 764-1013
Range on HMM: 2-264/269
Sequence Identity: 24% (65 aa)

LEQQYKNIIQFQPKDIHIASAMKQVNSIKNRG-AIFPIEGSRVHLTPKPGEDGSDYINASWLHGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLL
||. |... .    .     . |. | .|||  .| . .  || |.. .|.. |||||||...|..  ..||. | |.  ||.|||.|... . ...|.|
leeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivml

SSLDDINF--AQFWPDEaTPIESDHYRVKFLNKTNKSDYVSRDFVIQSIQ---DDYELTVKMLHCPSWP-EMSNP---NSIYDFIVDV--HERCN--DYR
| |.. |   |..||.| . .. ..  ||. .. ..|||. |.. .  ..    . .  |   ..|. ..  |   ... ..|  |  ... |     ..
snlteknrkcakyWpie-devqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgs

NGPIVIVDRYGGAQACTFCAISSLAIEMEYCSTANVYQYAKLYHNKRPGVWTSSEDIRVIYNIL
|||.  . |  .. .| |...|  ...   ....... |  ...|.. .| |    .|  |   
rsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyral

Phosphatase Ptp99A.AA Subfamily.RB.PD 766-990 28 5.1e-38 122.2 In-house 4-233 (261) Show / Hide
Range on Protein: 766-990
Range on HMM: 4-233/261
Sequence Identity: 28% (66 aa)

QQYKNIIQFQpKDIHIASAMKQVNSIKNRG-AIFPIEGSRVHLTPKPGEDGSDYINASWLHGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLSS
..|... ... ||  ...| ..||. |||   | |.. |||.|.    |...|||||....|..  |..|.|| |. .|..|||.|||.......|.|  
eeyeelkkvg-kdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmltq

LDD---INFAQFWPDEATPIESDHYRVKFLNKTNKSDYVSRDFVIQSiqDDYELTVKMLHCPSWPEMSNPN---SIYDFIVDVHERCNDY-RNGPIVIVD
| .   .   ..||.. .|.   . .|. |........| |.| |..  .. . .|. .|  |||. . |.   .. ||.  |.|. ..   ..|||.  
lvEkgkekceeYWPadeepvlyGdikvtllaekeldewvirefkiek--gkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHC

RYGGAQACTFCAISSLAIEMEYCSTANVYQYAK
  |   . || |.  |  ..|   . .|.    
saGvGRtGtfialdrllqaieendyvdvfgvva

Phosphatase Ptp99A.AA Subfamily.N_Choan_1.PD 766-978 25 1.9e-32 104.0 In-house 4-221 (262) Show / Hide
Range on Protein: 766-978
Range on HMM: 4-221/262
Sequence Identity: 25% (55 aa)

QQYKNIIQFQPKDIHIASAmKQVNSIKNR-GAIFPIEGSRVHLTPKPGEDGSDYINASWLHGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLSS
..|... . . ..   ||  .. |  |||   |.  . .||..||.  .  .|||||... |..  ...|.|| |. .....||||||.......|..  
eeyeklaeigvdntatask-adenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvtr

L---DDINFAQFWPDEATPIESDHYRVKFLNKTNKSDYVSRDFVIqSIQDDYELTVKMLHCPSWPEMSNPNSIYD---FIVDVHERCNDYRNGPIVIVDR
    . .   ..||||.. ..  ...||.|....|. |..| | . . ..  . .|. |.  .||.   |...   |  .|..  .  .. |.||    |
eieagklkChryWPdenselklgdvtvkslseeekktyierkfkl-eresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktkaplvihCs

YGGAQACTFCAISSLAIEME
  .. |. |.  |. ..|  
aGvGrtGtyialDrlvkave

Phosphatase Ptp99A.AA Subfamily.N9.PD 765-944 26 5e-32 102.7 In-house 3-185 (275) Show / Hide
Range on Protein: 765-944
Range on HMM: 3-185/275
Sequence Identity: 26% (48 aa)

EQQYKNIIQFQPKdIHIASAMKQVNSIKNRG-AIFPIEGSRVHLTPKPGEDGSDYINASWLHGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLS
..|..| . ...   .  .....|. |||   .  .. .||.|. ..... ||||||... |... . || || |. .|..|||.|||......|. . .
skeyadirnepve-GtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmtt

SLD---DINFAQFWP-DEATPIESDHYRVKFLNKTNKSDYVSRDFVIQSIQDDYELTVKMLHCPSWPEMSNPNSIYDFIvDVHER
     .  .|.|| .| . .|  ...|. ... ...||. | ..|. .... . .|      |||.   |.|  ... || |.  
rvvergrlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaasll-dvlek

Phosphatase Ptp99A.AA Subfamily.N5_RR.PD 787-1014 27 1.1e-30 98.2 In-house 21-261 (265) Show / Hide
Range on Protein: 787-1014
Range on HMM: 21-261/265
Sequence Identity: 27% (64 aa)

QVNSIKNR-GAIFPIEGSRVHLTPKPGEDG-SDYINASWLHGFRRL-RDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLSSLDDINF---AQFWPDEATP
.. |||  .|.| | ||| |... .||  |.|||| ...|...  . .. || |...||.|||.|.. ...| .|.|  | . ||...||.    |.  .
fgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdaedy

-IESDHYR--VKFLNKTNKSDYVSRDFVIQSIQDdYELTVKMLHCPSWPEMSNPNS---IYDFIVDVHERCN--DYRNGPIVIVDRYGGAQACTFCAISS
    .|. ..... ||  | .|... ..  | .||    ..||..  |..   . |.. .|.|  .  . ..|.|.    |  ..  | |||    ... 
eiserygdveikveeiverndysvrklvlkyler-versvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiaisi

LAIEMEYCSTANVYQYAKLYHNKRPGVWTSSEDIRVIYNILS
 .. .| .       .| |.  .||  ..|...|.       
avrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralc

Phosphatase Ptp99A.AA Subfamily.RN.PD 764-1006 28 2.4e-30 96.9 In-house 2-252 (264) Show / Hide
Range on Protein: 764-1006
Range on HMM: 2-252/264
Sequence Identity: 28% (71 aa)

LEQQYKNIIQFQPKDIHIASAMKQVNSIKNR-GAIFPIEGSRVHLTPKPGEDGSDYINASWLHGF-RRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVL
||.... . ... ..   . | .. |  |||  |..| . |||.|. .  .. ||||||| .     |   .| || |...|| |||||||.. .  .| 
lekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivn

LSSLDDI---NFAQFWPDEATPIEsDHYRVKFLNK-TNKSDYVSRDFVIQSIQDDYELTVKMLHCPSWPEMSNPN---SIYDFIVDVHeRCNDYRNGPIV
|..|..    . ...|||| . .  . | |... .     ||. | | .. .| .   ||  .|  ||||.. |    |. .||  ..   |  |||.  
ltrleeegvkqckrywpdeGsevy-hiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvn-ksyrGrscpiv

IVDRYGGAQACTFCAISSLAIEMEYCsTANVYQYAKLYH--NKRPGVWTSSEDI
  |  .. ....|  .   .      ..   | | |  ..|||.  . ...   
vhcsdGaGrtGvyilidlvlerllkG-vkeidiaatlehlrdqrpglvktkdqf

Phosphatase Ptp99A.AA Subfamily.N12.PD 780-1012 23 1.8e-29 93.9 In-house 23-264 (270) Show / Hide
Range on Protein: 780-1012
Range on HMM: 23-264/270
Sequence Identity: 23% (56 aa)

HIASAMKQVNSIKNRG-AIFPIEGSRVHLTPKPGEDGSDYINASWLHGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLSS---LDDINFAQFWP
... |..|  |||   |.| . |||.|. . .|.|||||||....| .    .| .| |...|..|||.|.|..| . ||..     |..  ...||.| 
steagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryWp

DE-ATPIESDHYRVKFLNKTNKS-DYVSRDFVIQSIqdDYELTVKMLHCPSWPEMSNPNSIYDFI--VDVHERCNDYRNGPIVIVDRYGGAQACTFCAIS
 ...| ....|.  .. . . |.. | . ..    . . .|. .|  .||.   |.|. . .  ..  .. ..  . |.|.    |  .. | .||    
eegeeelefgefevtleeekavdddflirtLkveaq--kesrkvyqfhytaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaid

SLAIEMEYC---STANVYQYAKLYHNKRPGVWTSSEDIRVIYNI
  ..     .. .|..      ..|. .  . |  ...|.    
yvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvyka

Phosphatase Ptp99A.AA Subfamily.N6.PD 764-1015 23 3.9e-29 93.1 In-house 14-292 (295) Show / Hide
Range on Protein: 764-1015
Range on HMM: 14-292/295
Sequence Identity: 23% (65 aa)

LEQQYKNIIQFQPKDIH-IASAMKQVNSIKNRG-AIFPIEGSRVHLTPK-PGEDGSDYINASWL--------HGFR-----RLRDFIVTQHPMAHTIKDF
........ . . .. .   .. |. |. |||   |.| . .|| |. . |   |||||||...        .|       . . .|.|| .. .|..||
fweefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdF

WQMVWDHNAQTVVLLSSLDDI---NFAQFWPDEATPIESDHYRVKFLNKTNKSDYVSRDFVIQSI-QDDYELTVKMLHCPSWPEMSNP---NSIYDFIVD
|.|||. |.. .|..    .      |..|||| |  |  ...|. .. ....||. |.|...   .|. . ..  .|  .||.. |   . . .|. ||
WrmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfled

VHERCNDY-RNGPIVIVDRYGGAQACTFCAISSLAIEMEYCS---TANVYQYAKLYHNKRPGVWTSSEDIRVIYNILSF
... ..  ..||||.    |  .. ||  |  .   .|        ....  |  ...| |.  ... ....|....| 
vnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqf

Phosphatase Ptp99A.AA Subfamily.RC.PD 812-1013 23 2.8e-27 87.0 In-house 69-283 (288) Show / Hide
Range on Protein: 812-1013
Range on HMM: 69-283/288
Sequence Identity: 23% (50 aa)

GEDGSDYINASWLHGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLSSLDDIN---FAQFWpDEATPIESDhYRVKFLNKTNKSDYVSRDFVIQS
.|.||.|||||....... . .| .| |.  |. |||.|.... .. .|.|. |.. .    |..| .| .    |   |.. .. . |||.| . ..  
seegskyinasfidsykkpekyiaaqGplketvddfwrmiferkvkvivmltelkeGdrekcaeyw-eeGkrayGd-vevdlkdtdkssdyilrklelvn

IQDDYELTVKMLHCPSWPEMSNPNSI---YDFIVDV---------HERCNDYRNGPIVIVDRYGGAQACTFCAISSLAIEMEYCSTANVYQYAKLYHNKR
..    .|  .   ||..   |.      ..|  |          |  ...  .|...  | |  .. .|.|. .|   .|.|.|. |   ..||..   
kkrkdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkar

PGVWTSSEDIRVIYNIL
 |   ..|..|      
plmvsveeqyillydvl

Phosphatase Ptp99A.AA Subfamily.N1.PD 778-984 26 1.7e-26 84.5 In-house 17-231 (268) Show / Hide
Range on Protein: 778-984
Range on HMM: 17-231/268
Sequence Identity: 26% (57 aa)

DIHIASAMKQVNSIKNR-GAIFPIEGSRVHLTPKPGedgsDYINASWLHGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLSSL---DDINFAQF
... ..| .. |  .||   . | . ||..|  .      |||||| ..  .  | .|.|| |..||.. ||||||..|...|..|  .   .|. ||.|
eletreaklpenrglnryrdvspydhsrikleradv----dyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqy

WPDEATP--IESDH--YRVKFLNKTNKSDYVSRDFVIQSIQDDYELTVKMLHCPSWPEMSNP---NSIYDFIVDVHER-CNDYRNGPIVIVDRYGGAQAC
| |     .. ..  ..||.. . .|| .. | . .. ....   ..   |   ||... |   ... .|.  |.|  .     ||.||.   |  .. |
wpqeeeeaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsg

TFCAISSLAIEMEYCSTAN
.. .... .|.|     | 
tlslvdtclveiektgdln

Phosphatase Ptp99A.AA Subfamily.N3.PD 767-955 28 4.9e-26 82.7 In-house 5-198 (261) Show / Hide
Range on Protein: 767-955
Range on HMM: 5-198/261
Sequence Identity: 28% (58 aa)

QYKNIIQFQPkDIHIASAMKQVNSIKNRG-AIFPIEGSRVHLTPKPgeDgsDYINASWL----HGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVL
|...... .| .. |  | |  |  |||   | | .  ||.|.  .     |||||...     ..     .|.|| |.|.| ||||||||.......|.
qfeelyrkkp-glaisaarkpenlaknryrdilpydatrvklkese--t--dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivm

LSSLDD---INFAQFWPDEATPIESDHYRVKFLNKTNKSDYVSRDFVIQSIQDDYELTVKMLHCPSWPEMSNPNSIYDFIVDVhERCNDYR---NGPIVI
| .| .   .   |.||..   .|  ...|.  .. ... || |..|..  . . | ..  |   .||. . |..  ||.  | || ...|   . |.|.
lttlverGrvkChqyWPetedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefv-ervrklrsgkeePvvv





Phosphatase Ptp99A.AA Subfamily.N_Nematode_5.PD 766-1013 20 5.6e-23 72.7 In-house 4-253 (258) Show / Hide
Range on Protein: 766-1013
Range on HMM: 4-253/258
Sequence Identity: 20% (54 aa)

QQYKNIIQFQPKDIhiASAMKQVNSIKNRGAIFPI-EGSRVhltpKPGEDGSDYINASWLHGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLSS
...... ...|.     . . . |. |||   ..| . .||    |.... ..|||||...     ...|.||.|  .|..|||.|| ... ..|||| .
tefeklaslkpnke--tckafeknlkknrskdvkilDetrV----kltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllve

LDDINFA--QFWPDEATPI-ESDhyrvKFLNKTNKSDYVS---RDFVIQSIQD---DYeLTVKMLHCPSWPEMSNPNSIYDFIV-DVHERCNDY--RNGP
 ....    .|.|.|.    . .    |.. .. | . ..     .... . .   .. . .|.|.  |.. . |.. .. |  ....  . .  .| |.
deelketavsffpletgdylnlg----kmfinnrkvevkedekkeytvevlpegcses-vfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgknap

IVIVDRYGGAQACTFCAISSLAIEMEYCSTANVYQYAKLYHNKRPGVWTSSEDIRVIYNIL
|.|  .|  .|.|| ..|    ...  .. |. .  |   ..|||. .|.    ..| .. 
vvvvsdlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaav

Phosphatase Ptp99A.AA Subfamily.N13.PD 766-1010 23 1.5e-22 71.6 In-house 4-251 (259) Show / Hide
Range on Protein: 766-1010
Range on HMM: 4-251/259
Sequence Identity: 23% (58 aa)

QQYKNIIQFQPKDiHIASAMKQVNSIKNR-GAIFPIEGSRVHLTPKPGedgsdYINASWLHGF--RRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLL
...|.. ...|.| .  .. |. |  |||   ..|.. .||.|  . |     |||||...        ..|..| |. .|.||||||||..|. .....
eefkelrelkpld-tcevgkkkenkdknryrnvlPydetrvklgdegg-----yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamv

SS---LDDINFAQFWPDEAT-PIE-SDHYRVKFLNKTNKSDYVSRDFVIQSIQDDYELTVKMLHCPSWPEMSNPNSIYDFIVDVHERCN-DYRNGPIVIV
.    . .   ..||...  ..  |. ..|. |. ......| |.. .. ..      |  |.  .||. . |.|  ...| |  . .  .||||.    
tlekekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqtdagPivvh

DRYGGAQACTFCAISSLAIEMEYCSTANVYQYAKLYHNKRPGVWTSSEDIRVIY
|  .. .. .|  .   .|     .| .  .   ..| ||  ...    .|   
csaGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvy

Phosphatase Ptp99A.AA Subfamily.N14.PD 768-938 25 7.8e-22 69.0 In-house 6-183 (275) Show / Hide
Range on Protein: 768-938
Range on HMM: 6-183/275
Sequence Identity: 25% (46 aa)

YKNIIQFQPkDIHIASAMKQVNSIKNRG-AIFPIEGSRVHLTPKPGEdGSDYINASWLHG--FRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLSS
| .| . .  | .. .|  ..|  |||   . | | .||.|.|   .  ..||||| ..     . |..||.| |. .|..|||||||... |.|.|.. 
yeripkkre-dallstaklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlte

L---DDINFAQFWPDE---ATPIESDHYRVKFLNKTNKSDYVSRDFVIQSIQDDYELTVKMLHCPSWPEMSNPNSIYDFI
         ...|..   .  .| ....|    ... . .... . .. .    | || .|    ||.   |. . .|. 
eeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgfl

Phosphatase Ptp99A.AA Subfamily.N_Choan_2.PD 793-1012 17 8.3e-20 62.3 In-house 25-260 (266) Show / Hide
Range on Protein: 793-1012
Range on HMM: 25-260/266
Sequence Identity: 17% (42 aa)

NR-GAIFPIEGSRVHLTPKPGEDGSDYINASWLHGFR-RLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLSSLDDIN---FAQFWPDEATP-IES--D
||   | |   .|| | .   .. . |||| ...||  . . .| .. |.. |.|.||.|.|.......|... | . .    ...|| |.   ..    
nRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkladg

HYRVKFLNKTNKSDYVSRDFVIQSiQDDYElTVKMLHCPSWPEMSN---------PNSIYDFIVDVHERCNDYRNG-PIVIVDRYGGAQACTFCAISSLA
. .|  |...... |. .   ..  ... . ...  .  .||. .          .... . . .|.. ... ... |... .  |   . |. ||    
kikvlalseekeegyiltrlrlek-kgetr-rlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtliaiDiav

IEMEYCSTANVYQYAKLYHNKRPGVWTSSEDIRVIYNI
  .|  . ..| .  .   ..|. .   .|  ...|. 
rlLeetkkvdvlaiieelRkdRmalvqhpeqyellyka

Phosphatase Ptp99A.AA Subfamily.N_Nematode_4.PD 777-985 22 7.5e-19 59.4 In-house 15-231 (264) Show / Hide
Range on Protein: 777-985
Range on HMM: 15-231/264
Sequence Identity: 22% (49 aa)

KDIHIASAMKQVNSIKNRGAIFPIEGSRVHLTPKPGEdgSDYINASWLHGFrRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLSSL--DDIN-FAQF
.   .|||... .       |. |. .|| |  .. .   ||| |||.        .| || |. .|..||| ||.   ...||.| .|  ....  |..
ppnvtasaseknsdknryadilcidetrvvlknrdpd--ndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcary

WPDEATP-IESDHYRVKFLNKTNK--SDYVSRDFVIQSIQDD-----YELTVKMLHCPSWPEMSNPNSIYDFIVDVHERCNDYRNGPIVIVDRYGGAQAC
.|..     .  .||.. ..|...  .| . . . . .....      .| || .. . |..   ||       .. ...|||.    |  ...|.  | 
ypeksekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkkkkkekPivvhcsaGvGrta

TFCAISSLAIEMEYCSTANV
   | .   |  .|      
tlvGidyatirirenseiev

Phosphatase Ptp99A.AA Subfamily.N20.PD 783-1013 27 9e-18 56.0 In-house 20-252 (257) Show / Hide
Range on Protein: 783-1013
Range on HMM: 20-252/257
Sequence Identity: 27% (62 aa)

SAMKQVNSIKNRG-AIFPIEGSRVHLTpkpgeDGSDYINASWLHGFRRLRD--FIVTQHPMAHTIKDFWQMVWDHNAQTVVLLSSL---DDINFAQFWPD
|  .  |  |||   |.| . .|| |         ||||||...      .  .| || |.  || |||||| . |.. . ...|.  ..||     |.|
sgnqpsnreknryrdilpydstrvplg-----kskdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywpi

E-ATPIESDHYRVKFLNKTNKSDYVSRDFVIQSIQDDYELTVKMLHCPSWPEMSNPNSIYDFIVDVHERCNDYRNGPIVIVDRYGGAQACTFCAISSLAI
  |.|| . |      .. | | .         .|| |.   ||.   | |   ||  ..   . .  ||.|.|  ..  | ..  .    .. ||  |.
slkkplelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarkshltgpmvvhcsagigrtgvflcvdvvfc

-EMEYCStANVYQYAKLYHNKRPGVWTSSEDIRVIYNIL
 .     ...| |.  . |. .. |.|.           
aivkncs-fnimdivaqmreqrsgmvqtkeqyhfcydiv

Phosphatase Ptp99A.AA PTPc_motif 916-1015 25 1.7e-17 65.37 SMART 1-92 (92) Show / Hide
Range on Protein: 916-1015
Range on HMM: 1-92/92
Sequence Identity: 25% (27 aa)

TVKMLHCPSWPEM-----SNP-NSIYDFIVDVHERCNDYRNGPIVIVDRYGGAQACTFCAISSLAIEMEYCSTANVYQYAKLYHNKRPGVWTSSEDIRVI
||. .|...||..     . | .|| .||  |..        |||..  .|   ..|||||...          ...|. |   . |||  .. |  . .
TVHHYHYTNWPDHVEKDSGVPEDSILEFIRHVRK--------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQYIFC

YNILSF
| .. .
YRCILE

Phosphatase Ptp99A.AA Subfamily.R_Nematode_3.PD 789-977 20 4.9e-17 53.4 In-house 24-224 (267) Show / Hide
Range on Protein: 789-977
Range on HMM: 24-224/267
Sequence Identity: 20% (42 aa)

NSIKNRGAIFPIEGSRVHLTPKPGEDGSDYINASWLHgFRRLRDFIVTQHPM--------AHTIKDFWQMVWDHNAQTVVLLSSLDD------INFAQFW
| ..| ..  .| .|| |        .|.|.|. .. .     .|.|| |.        . ||. ||.|. ..... || | ..       ......|..
vsedrrvevpllektrvvLkgygkrfkddfihAnvve-cpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeeekcseYy

PDEA-TPIESDHYRVKF--LNKTNKSDYVSRDFVIqSIQDDYELTVKMLHCPSWPEMSNPNSIYDfIVDVHERCNDYRnGPIVIVDRYGGAQACTFCAIs
. . .. . . ||    .|  . | . |..|. ....  | ||..|.  .|.| . |.. .  .... . .. ..  |.|. .  |  .. |. ||  |.
pekvdgelkfegvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepke-alelikfveksk-tpvvVHCsdGisRsatlaai-

SLAIEM
...   
elgyql

Phosphatase Ptp99A.AA Subfamily.N_Nematode_egg.PD 775-970 25 1.9e-16 51.5 In-house 12-207 (257) Show / Hide
Range on Protein: 775-970
Range on HMM: 12-207/257
Sequence Identity: 25% (50 aa)

QPKDIHIASAMKQVNSIKNRGAIFPI-EGSRVHLTPKPGEDGSDYINASWLHGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLSSLDDINFAQ-
..| .  |... .  | |    .  | |||.|  . |    |.| |  ..|   | .||..| |.  | .|||.||.  .| .|.|.|  . .  . .||
svdeislttaasdnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmltsakesercey

FWPD-EATPIES--DHYRVKFLNKTNKSDYVSRDFVIQSIQDDyeltVKMLHCPSWPEMS-NPNSIYdFIVDVHERCNDyRNGPIVIVDRYGGAQACTFC
  |. ..      .|.. |.  .|.| . |   .. .  |     . |.   |     . ..| . . |  .  .    |.|. |  | ..|.|. ||  
ywpkaeseslvtvpGslrienlkvdskadplfrvtklklvGgd----deelflehwqgdvnylsdvy-splrvlrklrn-lskpvvvqdilGvskaatlv

AI
  
ai

Phosphatase Ptp99A.AA Subfamily.R_Nematode_2.PD 780-996 20 4.7e-14 43.5 In-house 20-239 (261) Show / Hide
Range on Protein: 780-996
Range on HMM: 20-239/261
Sequence Identity: 20% (44 aa)

HIASAMKQVNSIKNRGAIFPIEGSRVHLTPKPGEdGSDyINASWLHGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLSSLD---DINFAQFWPD
.. . .. ... |.|    | . .       .|.  .. | | |.    . . ||.|| |.  | .||| ||  .. ...|.|..  ....| |    ..
svtesaaylpkdkhRypdvPCkpetavevivdgk-rvp-ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpl

EA-TPIESDHYRVKFLNKTN--KSDYVSRDFVIQSIQDDYE-LTVKMLHCPSWPEMSNPNSIYDFIvDVHERCNDYRNgPIVIVDRYGGAQACTFCAISS
 .....| ... .  | .   | . ..  . ...  ||. .   .||.   |.|  .   .. |   . .. |||.    |  .. .| ..  || |.| 
etsqkldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelf-eLlelvkksek-PivvhCsaGiGRtmafigtey

LAIEMEYCSTANVYQYAKLYHNKR
  | .. .  |  ...|       
lareveadptieltealkelrehR

Phosphatase Ptp99A.AA Subfamily.N_Fungi_PTP1.PD 778-878 27 1.1e-13 42.1 In-house 36-152 (343) Show / Hide
Range on Protein: 778-878
Range on HMM: 36-152/343
Sequence Identity: 27% (33 aa)

DIHIASAMKQvnSIKNR-GAIFPIEGSRVHLT--PKP------GEDGSDYINASWLHGF----RRLRDF--IVTQHPMAHTIKDFWQMVWDHNAQTVVLL
|. |.| ..     |||   |.| | |||.|   .|.         ..|||||..|.      .   ||  | || |.  |..||....   . . .. |
dviissGvel--faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsl

SSLDDINF---AQFWPDEA
.|... |     ..|.. .
tsdvelnlekcyrYWqegs

Phosphatase Ptp99A.AA Subfamily.N_Nematode_1.PD 765-956 19 2.2e-12 38.1 In-house 3-202 (265) Show / Hide
Range on Protein: 765-956
Range on HMM: 3-202/265
Sequence Identity: 19% (39 aa)

EQQYKNIIQFQPKDiHIASAMKQVNSIKNRGA-IFPIEGSRVHLTPKPgeDGSDYINASWLHGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLS
...... .|.... .. .  .. .. ||| . .  .. .|| |. .|    |||| | ..    . . || .| |. .||.||| ||  .. ...|.|  
rdefralkkfndee-kvkafkeaqeadknrykdvgcldknrvklaeep--lpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlc

SLD---DINFAQFWPDEATPI---ESDHYRVKFLNK------TNKSDYVSRDFVIQSIQDDYELTVKMLHCPSWPEMSNPNSIYDfIVDVHERCNdYRNG
|     .  |...| .  .    ...  ..   |.      ..... .    .  .   . ...|...   ||.   |.     .... |. . . .|||
kliekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadla-alelleavr-gskg

PIVIV
|.   
Pivvh

Phosphatase Ptp99A.AA Subfamily.N_Nematode_6.PD 801-935 24 8.8e-10 29.7 In-house 37-172 (253) Show / Hide
Range on Protein: 801-935
Range on HMM: 37-172/253
Sequence Identity: 24% (34 aa)

EGSRVHLTpkpgEDGSDYINASWLHGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLSSLDD---INFAQFWPDEATpiesDHYRVKFLNKTNKS
. .|..|.    .|   || |. ..   . | .|.|| |.  ||..||.|.     . .|.|  | .    . |.. .|.|. ..  | .  | . .   
dagrlkla----ddedfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvG----darkitklctviki

DYV------SRDFVIQSIQDDYELTVKMLHCPSWPEMSNPNSIY
   .|  .  . . | |  || .|  .||.   |.|.       
grkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsfl

Phosphatase Ptp99A.AA Subfamily.N_Nematode_eak.PD 795-931 21 1.4e-08 25.6 In-house 33-170 (281) Show / Hide
Range on Protein: 795-931
Range on HMM: 33-170/281
Sequence Identity: 21% (30 aa)

GAIFPIEGSRVHLTPKPgEDGSDYINASWLHGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLssLDDIN-----FAQFWPDEATPIESDHYRVK
| | .   |.||.    .   ||||| .      | .|.|  .  . .  ||||| . .. ..| |  |.|..     ....||..  ..  .. |.  .
vkivpqdrylvrltssq-lnrdGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivql--ledveekleksdkyfpdktevlkyGildve

FLNK-TNKSDYVSRDFVIQSIQDDYEltVKMLHCPSWPEMSNP
   ... .  | ....  .. ..  |.  .   | |.. |   
rkeyavkrniletrllilrkGnethr--vlhykvfGwtettlp

Sequence
Name Sequence Type Origin Length Description Download
Ptp99A.AA Protein None 1297 None Fasta, JSON
Ptp99A.NA RNA None 3891 None Fasta, JSON
Ptp99A.AA.PD1_475-743 Protein Phosphatase Domain None 269 None Fasta, JSON
Ptp99A.AA.PD2_763-1018 Protein Phosphatase Domain None 256 None Fasta, JSON