ia2
Species: D.melanogaster
Alias: ia2
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: RN
Protein domain

Protein domains of ia2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase ia2.AA Subfamily.RN.PD 959-1223 75 7.1e-150 488.6 In-house 1-264 (264) Show / Hide
Range on Protein: 959-1223
Range on HMM: 1-264/264
Sequence Identity: 75% (199 aa)

RLQREWEALCRYEAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIV
||..||||||.||||||..|.|......  ||  | |||||||| |.. |.||  ||.|||.|.|||||||||.|.||||.||.|.||||.||||.||||
rlekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvviv

ALCRLQENGEVACARYWPEEGAEVYHIYEVHLVSEHIWCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGrRSCPIV
.|.||.|.|  .|.||||.||.||||||||||||||||||||||||||||||.||||||||||||||||..||||.||.||.||||||||||| ||||||
nltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrG-rscpiv

VHGSAGAGRTGVYILLDLVLERMNKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVH
||.|.||||||||||.||||||..||..|||||||||||||||.|.|.|..||||.|.||||||.
vhcsdGaGrtGvyilidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaeevn

Phosphatase ia2.AA PTPc 959-1223 30 1.1e-99 338.35 SMART 1-308 (308) Show / Hide
Range on Protein: 959-1223
Range on HMM: 1-308/308
Sequence Identity: 30% (97 aa)

RLQREWEALCRYEAEPS--------AREAASQPQCA--GLNRPG-APLPYDHSRVVLNHLANA----EGLDYVNASTITDHDPRAPAYVAAQGPLPSTLA
 ...|.| |.|.. ...          . |  |  .    ||     ..|||.||.|...       || ||.||. |  . .|  .| ..|||||.|..
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY-WRPKRYICTQGPLPHTIE

HFWQMIWEQGAVVIVALCRLQEN--------GEVACARYWPEEGAEVYHIYEVHLVSEHIWCDDYLVRSFYLKNLRT--------SETRTVTQFHFLSWP
.||.|.|.|.  .|| ||.. |.        | . |..|||.|  ..|. ..|...||....||| .| |...|  .        |||||||..|. .||
DFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE-PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWP

HMGVPAQAKALLDFRRKVNKSYRGRR------------------SCPIVVHGSAGAGRTGVYILLDLVLERMNKGAREIDIAATLEHLRDQRAGVVATRQ
..|||  ....|||.|.|..... ..                  . ||||| |||.||||.....| .......    .||  .. ..|.||.| | | .
DHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN----VDIFQIVKMMRNQRPGMVQTEE

QFEFVLMAVAEEVH
|. |. ....| . 
QYIFCYRCILEYIK

Phosphatase ia2.AA Y_phosphatase 985-1220 37 9.5e-96 329.2 Pfam 1-243 (243) Show / Hide
Range on Protein: 985-1220
Range on HMM: 1-243/243
Sequence Identity: 37% (93 aa)

CAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGE-VA-CARYWPE---EG
    ||    ..|||.||.| .. . |. ||.||. |. ....  || ..|||.|.|...||.|.|.|.  .|| ||.. |.|  .  |..|||.   ..
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ

AEVYHIYEVHLVSEHIWCDDYLVRSFYLKNLRT--SETRTVTQFHFLSWPHMGVPAQ-AKALLDFRRKVNKSYRGRRSC--PIVVHGSAGAGRTGVYILL
 ..|  ..|..|||.  |.|| || | ..|  .  .||||||..|...||. |||   .|..|||.|.|.|...  ...  ||||| |||.||||.....
PMTYGDFQVTCVSEEH-CPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCAI

DLVLERMNKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
| ....| ..    ||  ...|.| ||.| | | .|..|. ....|
DIMCQQMEHEGTV-DIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

Phosphatase ia2.AA Subfamily.R_Anemone_2.PD 960-1222 41 2.8e-71 231.2 In-house 2-261 (262) Show / Hide
Range on Protein: 960-1222
Range on HMM: 2-261/262
Sequence Identity: 41% (109 aa)

LQREWEALCRYEAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTItDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVA
|..|.|.| | |....  ..| .|  .  ||    |.||..|| |..|.. || ||.||. | |   |  ||.|.|.||| |.||.|.|||.. ||| | 
lseeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyi-dGyrrkkayiatqaPlpetiedfWrmvWeqnsavivm

LCRLQENGEVACARYWPEEGAEVYHIYEVHLVSeHIWCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGRRSCPIVV
...|.| . ..||||..|.. |    |.| . .. ..||..||| .|. ...|.|.| |||. |||  |||...  |||. |.|.|  .     ||||| 
ltqeeergkakvhryWPskgsrsygklvvelke-evelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpivv

HGSAGAGRTGVYILLDLVLERMNKGArEIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEV
||| |||||.| .| .|||... |  .|.  |...||.||  .| |..|.||.  .. | .  
hcsaGvGrtGvfiavdillerikaea-lvdvfqtvkqlreqrnlmvqtkdqyefiydvlleal

Phosphatase ia2.AA Subfamily.R_Anemone_1.PD 963-1221 37 4.2e-69 224.2 In-house 5-256 (258) Show / Hide
Range on Protein: 963-1221
Range on HMM: 5-256/258
Sequence Identity: 37% (97 aa)

EWEALCryEAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRaPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCR
|.. |   |..    |.|....    ||    ...|||||||..| | |  ||.||| .  .| .  |..|.|.||..|.. ||.|.|.. . ||| |  
efqrlk--eikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdkt-rafiatqapleetvedFWrmvwqekigviVmLtn

LQENGEVACARYWPEeGAEVYHIYEVHLVSEHIWCdDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSyRGRRSCPIVVHGS
|.|. .  | .|||. ..| |  ..|.| ..     || .|.. |.. ...|.|.|.|.||..||.||| .|.|.|..||||.|| . . . |.||| ||
liegekkkchqYwPd-stekygelrvslrkkevfa-dyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqks-slagarpvvvhCs

AGAGRTGVYILLDLVLERMNKgAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEE
| ||||... .| .||.. |  . .||  ... .| .|. .| |..|.|. .|| |   
aGvgRtGaflvidamleqakk-ekvvDifnyvkairedrphmvqtkeqyvfihlavlea

Phosphatase ia2.AA Subfamily.N12.PD 975-1222 42 2.3e-66 214.8 In-house 22-269 (270) Show / Hide
Range on Protein: 975-1222
Range on HMM: 22-269/270
Sequence Identity: 42% (105 aa)

SAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDpRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARY
..||.....    ||    ||||.|||.|..  . || ||.||. |   .    .|.|||||||.||  ||.||||.   ..| .||. |.|   |.|||
ysteagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgve-gkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCery

WPEEGAE-V-YHIYEVHLVSEHIWCDDYLVRSFYLKNLrtSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKsYRGRRSCPIVVHGSAGAGRTGVYI
|||| | . .  .|| | .|.   ||.|.|.. ...   .|.|.|.|||. .||  |||..|| ||.. ..|.. .... .|.||| ||| ||||. | .
WpeegeeelefgefevtleeekavdddflirtLkveaq--kesrkvyqfhytaWPDhgvPssaksllelielvre-lqesedaPlvvhCsaGvGrtGtii

LLDLVLERMNKGAR--EIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEV
|.| | ....    |.|.   . .|| ||| .| |..|.|.| .|||| |  
aidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv

Phosphatase ia2.AA Subfamily.RB.PD 974-1219 37 9.8e-66 212.9 In-house 15-257 (261) Show / Hide
Range on Protein: 974-1219
Range on HMM: 15-257/261
Sequence Identity: 37% (93 aa)

PSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRaPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACAR
.| .||....    ||    |||||||| |..|.. .. ||.||. | ..  .   |.|.|||||.|  .||.|.||. . .|| | .| |.| . | .|
dqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynsp-reyiatqGPlpetvddfWrmvwekkssiivmltqlvEkgkekcee

YWPEEG-AEVYHIYEVHLVSEHIwCDDYLVRSFYLKNlrTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGR-RSCPIVVHGSAGAGRTGVY
||..  . .|   .|.|..|.   |.. .|.| ...   .|.|.|.|.||.|||  ||| ..|.|||| |.|... . .  .||||| ||| ||||..| 
YWPadeepvlyGdikvtllaeke-ldewvirefkiek--gkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHCsaGvGRtGtf

ILLDLVLERMNKgAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVA
|| .|.....    .|..... .|| .|. .| | .|. |.  ...  
ialdrllqaiee-ndyvdvfgvvaelReeRnllvqtekqyifihecll

Phosphatase ia2.AA Subfamily.N_Choan_1.PD 975-1220 36 1.4e-64 209.1 In-house 16-259 (262) Show / Hide
Range on Protein: 975-1220
Range on HMM: 16-259/262
Sequence Identity: 36% (90 aa)

SAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRApAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARY
.. .|. ...    ||      ||..|| ...  ...  ||.||. .   .  . .|.|.|||.|..|..||||.||| ...||. |  |.|.. | |||
ntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgek-eyiatqgPvPaslvsfWqmvweqkvsaivmvtreieagklkChry

WPEEGAEV-YHIYEVHLVSEHiWCDDYLVRSFYLkNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGRRSCPIVVHGSAGAGRTGVYIL
|.| .|. .  . |. .||.     |. | | | . ...|||.|.|.....||  ||||..|.||.||..|.|  . .. .|.|.| ||| ||||.|| |
WPdenselklgdvtvkslsee-ekktyierkfkl-eresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktkaplvihCsaGvGrtGtyia

LDLVLERMNKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
| ....... | ..|. |....|| .|  .| |  |.|||  || . 
lDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavld

Phosphatase ia2.AA Subfamily.RA.PD 960-1220 40 7.4e-64 206.8 In-house 2-263 (266) Show / Hide
Range on Protein: 960-1220
Range on HMM: 2-263/266
Sequence Identity: 40% (106 aa)

LQREWEALCRYEAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRaPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVA
|. |...|   .   .  ..|....    ||    ||||.|||.|...   |  ||.||| |  .  .   ..|||||.  |.  ||.||||| .  || 
leeefkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrek-dkfiaaqGpkeetvedfwrmiweqksativm

LCRLQENGEVACARYWPEEGAEVYHIYEVHlVSEHIWCDDYLVRSFYLK----NLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGRRSC
|  |.| .|  ||.|||.||.  |    |. | ..  . || || | ..    . |  ..| |.|||| |||..||||..| .|.. .||.|  .   . 
ltelkerkeekcaqywpdeGlvtyGeirve-vkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanh

PIVVHGSAGAGRTGVYILLDLVLERMnKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
||||| |||.|||| .| || ||||. |  | .|.  ....|| ||. .| | .|.||.  .. |
pivvhcsaGvGrtGtfivldavlerv-kaerkldvfeavkrlrlqrpqmvqtleqyefiykvlle

Phosphatase ia2.AA Subfamily.R_Sponge_2.PD 978-1222 39 7.6e-63 203.5 In-house 18-261 (262) Show / Hide
Range on Protein: 978-1222
Range on HMM: 18-261/262
Sequence Identity: 39% (97 aa)

EAASQPQCAGLNRPGAPLPYDHSRVVLNHlANAEGLDYVNASTITDHDpRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPE
..| ...  | ||    ||||.||| |..  . .. ||.||| .  .  |  ||.|.||||..|.. || |.||.    || |.|.|||.  ||.||||.
siaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgyk-rrkayiatqgPlketveDfWRmvweykvstivmltnleengkekcakYWPe

E--GAEVYHIYEVHLVSEHIwCDDYLVRSFYLKNLRTSETR-TVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGRRSCPIVVHGSAGAGRTGVYILL
  ..  |  ..| |..|.    || .| . |.. ..|| . .||||||..||  .||..| .||....|... .  .. .|.|. |.|.|||| .| || 
kvdeeveygkfkvtlkeeek-ladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsdgvgrtGtfial

DLVLERMnKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEV
||||. |  .|||.  .|..|| .| |.| . .|..|.  |..| .  
dsvlerl-kaeeeidvfevlktlrtkriglvqdaaqYvfihdalleyi

Phosphatase ia2.AA Subfamily.RK.PD 960-1221 34 4.4e-59 190.9 In-house 2-265 (267) Show / Hide
Range on Protein: 960-1221
Range on HMM: 2-265/267
Sequence Identity: 34% (91 aa)

LQREWEAL--CRYEAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAeGLDYVNASTItDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVI
|. |.|.|    .| .    ..| ...    || .  |.||.|.|.|  . .    ||.||. | |   |. |....||||..|.. ||........  |
lkeefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaali-dsykrpaafivtqgPlqetvkdfWrlvydencasi

VALCRL-QENGEVACARYWPEEGAEVYHIYEVHLVSEHIWCdDYLVRSFYLKN--LRTSETRTVTQFHFLSWPHM-GVPAQAKALLDFRRKVNKSYRGRR
| |  | .|.| | | .||||..   |   .|.||. .. . |..|| | ...     .|.|.| ||.||.||.  .|| ....||.. |.|.||    .
vmlteldvevgrvkClkyWPedtevrygdikvelveaelda-dlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeeee

SCPIVVHGSAGAGRTGVYILLDLVLErMNKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEE
  .|||| .|||||.|..| .| ||| | .  . .|.  .   ||.... .| | .|..||  .. | 
eGrivvhClaGaGrsGtfiaidivle-mieregvvdvfnavktlrnrkvnmveteeqykfvydvilea

Phosphatase ia2.AA Subfamily.N3.PD 976-1219 38 5.1e-59 190.7 In-house 17-257 (261) Show / Hide
Range on Protein: 976-1219
Range on HMM: 17-257/261
Sequence Identity: 38% (95 aa)

AREAASQPQCAGLNRPGAPLPYDHSRVVLNhlaNAEGlDYVNASTITDHDPR---APAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACA
| .|| .|. .  ||    ||||. || |.   ..|  ||.||...    |       |.|.||||..| ..||||.||| . .|| |  ||.| | | .
aisaarkpenlaknryrdilpydatrvklk---eset-dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkCh

RYWPEEGAEV-YHIYEVHLVSEhIWCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKsYRGRRSCPIVVHGSAGAGRTGVY
||||.. |. .  ..|.. .|      |..| ..||. .|.| |...|. .|.||  ||| ... .|.| ..|.| .|  ..|.||| ||| |||||.||
qyWPetedelefgefsvrceke-detksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrk-lrsgkeePvvvhCsaGigrtGvl

ILLDLVLErMNKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVA
|.. |  .   |... . . . ..||||| .| | .|..||  |.   
illetala-lieaaepvypldivrtmrdqramlvqtvsqykfvCeail

Phosphatase ia2.AA Subfamily.N6.PD 961-1220 34 1.3e-58 189.7 In-house 15-292 (295) Show / Hide
Range on Protein: 961-1220
Range on HMM: 15-292/295
Sequence Identity: 34% (95 aa)

QREWEALCRYEAEPSA-REAASQPQCAGLNRPGAPLPYDHSRVVLNHL-ANAEGLDYVNASTI--------TDHDPR----APAYVAAQGPLPSTLAHFW
..|.| |...|.|    |. ..... .  ||    ||.||.||.|.    .  | ||.||. |        . . .        |.|.||.|..|.. ||
weefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdFW

QMIWEQGAVVIVALCRLQENGEVACARYWPEEGA-EVYHIYEVHLVSEhIWCDDYLVRSFYLKNL-RTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRK
.|.|.. . ||| . .  | |.  ||||||.|.  . .  ..|. .||    .|| .| | ...    .|.|.. |.|| .|||||......|.| ..||
rmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisE-kstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfled

VNKSYRG-RRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGA--REIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
| ..  ... ||||| ||| |||| .|..| ||. ...     .|||  .....| ||.|.| | .|..||..||.   
vnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqf

Phosphatase ia2.AA Subfamily.N9.PD 982-1220 39 1e-57 186.8 In-house 23-272 (275) Show / Hide
Range on Protein: 982-1220
Range on HMM: 23-272/275
Sequence Identity: 39% (99 aa)

QPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTItDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPE--EG
..     ||    | ||..||.|..| . |  ||.||. . |   .  |..|.||||. |   ||.|.||| ..|||   |. |.| . |..|||.  | 
lranleknrytdvlcydetrvklakldedeasdyinanfv-dGykqkkafiatqGplkktvsdfwrmvweqevlvivmttrvvergrlkcgqywpleees

AEVYHIYEVHLVSEHIwCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNK-----------SYRGR-RSCPIVVHGSAGAGR
.. .  ..|. |. .   .|| ||.. .|| .|.|.|.|| | |||||  ||| .|..|||...|| .           . .|..  ||||| ||| |||
saefgdlsvsnvevev-eedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdeskghlsgPPivvhcsaGiGr

TGVYILLDLVLERMNKGArEIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
| .| ||. |.|... .  .|.  |...|| |||  . | .|.||  .|| | 
tGtfitldiclarleevg-tvdvvetvkllrtqrafsiqtpeqyefcylavle

Phosphatase ia2.AA Subfamily.RG.PD 960-1220 33 6.4e-57 184.1 In-house 2-261 (264) Show / Hide
Range on Protein: 960-1220
Range on HMM: 2-261/264
Sequence Identity: 33% (88 aa)

LQREWEALCRYEAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDpRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVA
|....|.. . ...    |......    ||    .....||| |. |.. .| ||.||| |. .  |. .|...||||..|.  ||.||||. | .|| 
leeqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyr-rskeyivtqgplketiedFWrmiWehnaqiivm

LCRLQENGEVACARYWPE-EGAEVYHIYEVHLVSEHIWcDDYLVRSFYLKNLRTSETRT--VTQFHFLSWPHMGVPAQAKALLDFRRKVNKSyRGRRSCP
|  |.|.|   ...|||. .... .  ..| |.|..   ..| ||.| ||| .. . ..  |.|.|. .|| ||.| ..   || .| ... . ... ||
ltdldekgrrdedvyWPkkdeplelealkvtllskekl-skytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaa-nkeeaGP

IVVHGSAGAGRTGVYILLDLVLERMNKgAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
||| |||.||.|.|| || .|....|    ...  .| ..| .| |.|.|. |. |.  |. | 
ivvhdsaGvgragtyialdtllqqlek-eeavnvyqvlklirakRpglvtteEqyvfiydalle

Phosphatase ia2.AA Subfamily.N13.PD 984-1219 37 1e-54 176.9 In-house 25-255 (259) Show / Hide
Range on Protein: 984-1219
Range on HMM: 25-255/259
Sequence Identity: 37% (90 aa)

QCAGLNRPGAPLPYDHSRVVLNHLANaegldYVNASTIT-DHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEV
.    ||    ||||..|| |.  ..     |.||| |    .     |.|.||||| | . ||||.||| | ||. .   .|.|.| | |||||.  . 
enkdknryrnvlPydetrvklgdegg-----yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPerknkk

YHIYE---VHLVSeHIWCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRgrRSCPIVVHGSAGAGRTGVYILLDLVLE
 ....   |.|.      |.. ||.. .|.....|.| |....| .||  |||..|. |. | ..|..  .   . |||||||| ||.||.| .| ||. 
lkvsnrlevellk-vqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt--dagPivvhcsaGiGrsGvlitidvvlg

RMNKGArEIDIAATLEHLRDQRAGVVATRQQFEFVLMAVA
...   |.|.  ....||.|| ||| |..|. ||  |.  
lierdk-efdvkeivrklreqrqgvvqtkdqyifvykail

Phosphatase ia2.AA Subfamily.R_Ecdysozoa.PD 960-1220 32 3.5e-54 174.9 In-house 2-266 (269) Show / Hide
Range on Protein: 960-1220
Range on HMM: 2-266/269
Sequence Identity: 32% (87 aa)

LQREWEALCRYEAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRApAYVAAQGPLPSTLAHFWQMIWEQGAVVIVA
|..|.| | .    .   ... .   |  ||  .  ..|. ||.|...   |  ||.||| |  .. .   ..|||.|. .|.||.||.||   .|| | 
leeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekk-kfiaaqdPveatigDfWrmiaeqevtlivm

LCRLQENGEVaCARYWPEEGAEVYHIYEVHLVSEHIwCDDYLVRSFYLKNLR---TSETRTVTQFHFLSWP-HMGVPAQAKALLDFRRKVNKSYRGR---
 |.|. .  ||.|||.|    |    |.||||.  ..||  |.... .       ..| |.|... .|.  . || .|..||.. ..|.. |.       
lsnlteknrk-cakyWpiedevqygdilvklvseek-hsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnkls

-RSCPIVVHGSAGAGRTGVYILLDLVLERMNKgAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
  ||||| |||.||.|... |||.|.....   ..|| .|  .|| ||. .|   .|..|.  |.|.  
gsrsPivvhCsaGvgrsgifvaldlllqqlka-edkvdifetvkkLrsqrnllvqsleqyvflyralad

Phosphatase ia2.AA Subfamily.N1.PD 977-1221 37 7.7e-54 174.0 In-house 20-266 (268) Show / Hide
Range on Protein: 977-1221
Range on HMM: 20-266/268
Sequence Identity: 37% (93 aa)

REAASQPQCAGLNRPGAPLPYDHSRVVLNHLANaeglDYVNASTItDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWP
..| .|.  ||||     ||||||..|..  .    ||.||| . . .     |. .||||| |  |||||.||| .  .. | .. |.... || |||.
treaklpenrglnryrdvspydhsrikleradv----dyinaslv-eleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywp

EEGAE----VYH-IYEVHLVSEHIwCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYR-GRRSCPIVVHGSAGAGRTGV
|  |    . .  ..|.|.||..  . .||| . |..|.|.|||....||.  || .|||   .|.|.|  || .|    .|.|.| ||| ||.| . |.
qeeeeaellleetklkvkliseer-ksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsgt

YILLDLVLERMNKGAR--EIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEE
| .| ...|      .||   | .|| .| |.. | .| .|  .|. |     
lslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiaileg

Phosphatase ia2.AA Subfamily.N5_RR.PD 989-1219 34 2.3e-53 172.3 In-house 27-261 (265) Show / Hide
Range on Protein: 989-1219
Range on HMM: 27-261/265
Sequence Identity: 34% (83 aa)

NRPGAPLPYDHSRVVLN-HLANAEGLDYVNASTITDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEG-AEV---Y
||  . || ..|||.|. . ...| ..|.||  |  .| .  ||||.|||||.|.| ||.||... . ||| | .|.|. .  ||.|.|..  .|.   |
nryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdaedyeisery

HIYEVHlVSEHIWCDDYLVRSFYLKNLRTsETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGR--RSCPIVVHGSAGAGRTGVYILLDLVLERM
   |.. |.| . ..|| ||...||.|.   .|.|. . . .|| . .| ....|||. ..|..| . .  .  |.||| ||| ||||..|  .. . ..
gdveik-veeiverndysvrklvlkyler-versvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiaisiavrql

NKGaREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVA
..    .|.  .  .|| .| |.| |..|.|..  |..
ree-ivvdvlkivcnlrldrGGmvqtseqyelihralc

Phosphatase ia2.AA Subfamily.N14.PD 963-1218 32 7.8e-51 164.0 In-house 5-270 (275) Show / Hide
Range on Protein: 963-1218
Range on HMM: 5-270/275
Sequence Identity: 32% (88 aa)

EWEALCRYEAePSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAeGLDYVNASTITDH-DPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALC
|.| . . ..  .  ..|. |. |  ||    |||...|| |.   ..   .|.|||.|      .   |..|||||. |.  ||||.||||  .|| | 
eyeripkkre-dallstaklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlt

RLQENGEVACARYWPEEGAEVYHI-YEVHLVSEHIW--CDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKV-------NKSYRG
. .|.|   . .|.|... .  .. .. . |...     | .  ... || | ..| |||  . .  ||  |||   | .|.| ..|       |..  .
eeeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnseves

--RRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGaREIDIAATLEHLRDQRAGVVATRQQFEFVLMAV
   .. |..|| |||.||||| || ||... .... .||||  .|..|| ||  .|.|  |..||  ..
vkeskPPvlvhCsaGvGrtGvlilsdlliatlehn-eeidikkvlarLrkqrmllvqtlaqykfvykvl

Phosphatase ia2.AA Subfamily.RC.PD 963-1220 29 4.6e-49 158.3 In-house 5-285 (288) Show / Hide
Range on Protein: 963-1220
Range on HMM: 5-285/288
Sequence Identity: 29% (83 aa)

EWEALCRYEAEPSAREaASQPQCAGLNRPGAPLPYDHSRVVL-------------------NHLANAEGLDYVNASTITDHDpRAPAYVAAQGPLPSTLA
|.. | .. .  . .. | ...    ||    ||||. || |                   ..    || .|.||| |  .  .   |.||||||  |. 
efqrlpsvrskrtiki-arkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsyk-kpekyiaaqGplketvd

HFWQMIWEQGAVVIVALCRLQENGEVACARYWpEEGAEVYHIYEVHLvSEHIWCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDF--
 ||.||.|. . ||| | .|.|  .  ||.|| ||| . |   ||.|  ..  . ||..| . |.| .  ..|.|||. . ||...|.. | ||..    
dfwrmiferkvkvivmltelkeGdrekcaeyw-eeGkrayGdvevdl-kdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliq

-------RRKVNKSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKgAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
     ...  ....   | |..|| ..|..|||..| |. .|| ..     .|.   . .|| .|...| . .|. ..  ...|  
vvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallalleslea-eekvdvfqvvkklrkarplmvsveeqyillydvlve

Phosphatase ia2.AA Subfamily.N_Choan_2.PD 986-1221 32 6.5e-49 157.6 In-house 22-264 (266) Show / Hide
Range on Protein: 986-1221
Range on HMM: 22-264/266
Sequence Identity: 32% (79 aa)

AGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHI
. |||    ||  ..||.|..| . .   |.||  .   | .  .|.||.||||.|| .||.||||. .  || .  |.|.||.||||.|  |  ..   
krlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkl

--YEVHLVSEH-IWCDDYLVRSFYLKNlrTSETRTVTQFHFLSWPHMGVPAQAK------ALLDFRRKVNKSYRGR-RSCPIVVHGSAGAGRTGVYILLD
... ....    . |...   |..   .|||... |.. .||  ||| ..        ||.  |.|... .   .. |..|| ||| ||||. |..| ..
adgkikvlalseekeegyiltrlrlek--kgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtliaiD

LVLERMNKGaREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEE
. ...  ...|..| .|.|| .|  .| . .|.|..  ||.|    
iavrlLeet-kkvdvlaiieelRkdRmalvqhpeqyellykavvey

Phosphatase ia2.AA Subfamily.N23.PD 996-1220 31 2e-47 153.0 In-house 113-347 (350) Show / Hide
Range on Protein: 996-1220
Range on HMM: 113-347/350
Sequence Identity: 31% (73 aa)

PYDHSRVVLNHLAN-AEGLDYVNASTITDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEG--AEVYHIYEVHLVS
|..||.|. ...  .  ||.||. . .  | .| ..|.|||..|||| ||.|.||| . ||| | . .|..   |..|||..   ......| | |..  
rhdpnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslks

EHiWCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSY--------RGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKG
 . .  | . |.   .|  |.|...|. .|...|||.  . ||.|  .|.. |         |    ||..| ||| ||||.. ..  ... ...|   |
lr-ssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltag

AREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
.|   ...|| ||  .| ........  || |    
ngiiniprvvrrlrqqRkymvqkkvilkklyeavle

Phosphatase ia2.AA Subfamily.N20.PD 974-1220 34 1.4e-37 120.7 In-house 15-254 (257) Show / Hide
Range on Protein: 974-1220
Range on HMM: 15-254/257
Sequence Identity: 34% (84 aa)

PSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHlanaeGLDYVNASTITDHDP-RAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACA
|   ..  ||     ||    |||| .|| | .       ||.||| |   .      |.|.|||| ||.  ||||. |. . ||  . || | . | .|
pgefnsgnqpsnreknryrdilpydstrvplgk-----skdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcy

RYWPEEGAEVYHIYE--VHLVSEHIwCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYrgrRSCPIVVHGSAGAGRTGV
||    .   .    | |   .|  . ...| | . .  |  ...| |..|  ||  | || | ... . |   ||.. |.||| ||| |||||.. .|.
hywpislkkplelkhfrvflenyqi-lqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarksh---ltgpmvvhcsagigrtgv

YILLDLVLERMNKGArEIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
|.  . | .  ..|   . ..|.||.|.| |..|. |.   | |      
flcvdvvfcaivknc-sfnimdivaqmreqrsgmvqtkeqyhfcydivle

Phosphatase ia2.AA Subfamily.N_Nematode_4.PD 995-1221 31 1.2e-36 117.6 In-house 36-262 (264) Show / Hide
Range on Protein: 995-1221
Range on HMM: 36-262/264
Sequence Identity: 31% (72 aa)

LPYDHSRVVLNHLANaeGLDYVNASTITDHDprAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAE--VYHIYEVHLVS
|  |..||||..       ||. || ..  |     |...||||. ||. || |.... . |.| || | |.|   ||||.||.  .  .. .|...|| 
lcidetrvvlknrdp--dndyihaswmrmPd--kfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypeksekvvkfGkyritlve

EHIW-CDDYLVRSFYLKNLR-----TSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKsyrGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKgAR
..     | ...|. . |       .||   |  ...  |.    | .|...... . |.|... ||||| ||| |||  .. .|.   |..    ||..
kkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk---kkkekPivvhcsaGvGrtatlvGidyatirire-ns

EIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEE
   . .||  | . | .. || |.|. ..|     
eievldivrelramrlkavqshlqflfllvvliel

Phosphatase ia2.AA PTPc_motif 1117-1220 34 2.1e-35 124.89 SMART 1-92 (92) Show / Hide
Range on Protein: 1117-1220
Range on HMM: 1-92/92
Sequence Identity: 34% (38 aa)

TVTQFHFLSWPHM-----GVPAQAKALLDFRRKVNKSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGAREIDIAATLEHLRDQRAGVVATRQQF
||...|...||..     |||   ...|.|.|.|.|        ||||| |||.||||.....|.....       .||  |....|.||.| | | .|.
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK--------PIVVHCSAGCGRTGTFCAIDMMMQQ-------VDIFQTVKEMRKQRPGMVQTEEQY

EFVLMAVAE
 |. ....|
IFCYRCILE

Phosphatase ia2.AA Subfamily.N_Nematode_1.PD 960-1214 29 1e-34 111.1 In-house 2-256 (265) Show / Hide
Range on Protein: 960-1214
Range on HMM: 2-256/265
Sequence Identity: 29% (77 aa)

LQREWEALCRYEAEPsAREAASQPQCAGLNRPGAPLPYDHSRVVLNHlaNAEGLDYVNASTITDHdPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVA
|. |..|| ... |    .| .. | |. ||       |..||.|..  ..   ||. |  ..    ..  .. ||.|| .|.|.|| |.  .    || 
lrdefralkkfndee-kvkafkeaqeadknrykdvgcldknrvklae--eplpsdyihanyvgtp-tnpkrficaqaPldktiadfwymvlqekveaivm

LCRLQENGEVACARYWPEEGAEVYHIYEV--------HLVSEHIWCDDYLVRSFYLKNLR-TSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSyr
||.| |.|.. || |.| .  |. .. |         .| ....  |.  ..   |.     ..||.||....  ||  |||.   | |..  .|..|  
lckliekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrgs--

grrSCPIVVHGSAGAGRTGVYILLDLVLERMNKGAREIDIAATLEHLRDQRAGVVATRQQFEFV
     ||||| ||| ||||  . ....|... .| .  |.   ....|.||.  . | .|. ||
---kgPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfv

Phosphatase ia2.AA Subfamily.R_Nematode_3.PD 1001-1220 24 1e-32 104.6 In-house 39-264 (267) Show / Hide
Range on Protein: 1001-1220
Range on HMM: 39-264/267
Sequence Identity: 24% (56 aa)

RVVLNHLANAEGLDYVNASTITDhdPRAPAYVAAQGPL--------PSTLAHFWQMIWEQGAVVIVALCRLQE---NGEVACARYWPEEGAEVYHIYEVH
||||.   .    |...|. ..   |     . .|.|.         ||.  ||.|| .... ..| ||  .|   ..| .|..|.||.  .. .. .| 
rvvLkgygkrfkddfihAnvvec--pnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeeekcseYypekvdgelkfegvs

LVS---EHIWCDDYLVRSFYLkNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSyrgrrSCPIVVHGSAGAGRTGVYILLDLVLERMNKGAR
.     ..   .|   |.. . ..   .. |||  .. .|.. ..| ..| .|.  ..|.|||.||| |.| .|...    .|. . . |  ...|... 
vkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfveks-----ktpvvVHCsdGisRsatlaaielgyqliikskg

EIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
...|| |||| . | ... ||.. . .       
kldllslikelrkqRagaiqtelelafvilgilk

Phosphatase ia2.AA Subfamily.R_Nematode_2.PD 1029-1216 30 1e-30 98.0 In-house 69-254 (261) Show / Hide
Range on Protein: 1029-1216
Range on HMM: 69-254/261
Sequence Identity: 30% (57 aa)

PAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHI--YEVHLVS-EHIWCDDYLVRSFYLKNLRT-SETRTVTQFHFL
..|.||||  |   || |.  .    || ||.  |. .  |..|.| |  .  ..  .... || |.|  |.  .|....     .||||| . . .||.
krfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqye

SWPHMGVPAQAKALLDFRRKVNKSYRgrrscPIVVHGSAGAGRTGVYILLDLVLERMNKgAREIDIAATLEHLRDQRAGVVATRQQFEFVLM
 |||   . | .    | || .     ||||| ||| |||. .|  . . .....  ..|.. .|..||..|   . |..|. .. .     
eWpdrgvPkshaelfeLlelvkksek-----PivvhCsaGiGRtmafigteylarevea-dptieltealkelrehRwkgiqtesqlywltl

Phosphatase ia2.AA Subfamily.N_Nematode_6.PD 1014-1220 30 3e-29 93.3 In-house 49-250 (253) Show / Hide
Range on Protein: 1014-1220
Range on HMM: 49-250/253
Sequence Identity: 30% (62 aa)

DYVNASTITDHdPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHIYEV--HLVSEHIWCDDYLVRSFYLKNLR
|. |. .  . ..   .. .|.|| .|. .||.||  .|   || || | |.|.  .|.| ...  .  .| ..   .  ..   |  ||||       .
fyihanlvkis-tkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvGdarkitklctvikigrkdidkilvrslkrivka

TSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRgrrscPIVVHGSAGAGRTGVYILLDLVLERMNKgAREIDIAATLEHLRDQRAGVVATRQQF
 |   |  .|. .||  ||| . .. | .   | |. .     ||||| ||| ||||  .|..|| . . .. ...   | .||..|.  | |  |. ..
gdeevivkhihWanWPdhGvPdsflsalrllsvvkkdkk-----PivvhCsaGvGrtGtlaliliilealrl-pdfqgvkdllvklreerfravqtevqy

EFVLMAVAE
|  | |   
lyalrcvle

Phosphatase ia2.AA Subfamily.N_Nematode_5.PD 989-1219 26 1e-28 91.3 In-house 29-254 (258) Show / Hide
Range on Protein: 989-1219
Range on HMM: 29-254/258
Sequence Identity: 26% (62 aa)

NRPGAPLPYDHSRVvlnHLANAEgLDYVNASTITDHDPRApAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACaRYWPEEgAEVYHIYEV
||   .  .|..||   .|.. .  .|.|||.|.  | .   .. .| |||.| . ||.|. ..  . .| |.. .|  | |.  ..|.| .. |  .. 
nrskdvkilDetrV---kltded-dsYinaskiklddlek-kliltQlPlpdteedFWrmvyqekitsvvllvedeelketav-sffple-tgdylnlgk

HLVSEHIWCDDYLV-RSFYLKNLRT--SETRTVTQFHFLSWPHMGVPAQAKALLDfrRKVNKSYRGR--RSCPIVVHGSAGAGRTGVYILLDLVLERMNK
 ..       .      .... |    ||   ..  |.  |..  ||.. |...   |...|.    .. |.||. ..|.||.|  .||... | .|.| 
mfinnrkvevkedekkeytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvik--raiekvlskkqgknapvvvvsdlGlgRagtflllsvaieqlnn

GaREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVA
 |..|...|...|.||.|.| . .|. .| .||.  
g-kepnideilkkirsqRpgavesliqyasvyaavl

Phosphatase ia2.AA Subfamily.N_Fungi_PTP1.PD 988-1085 30 1.4e-17 54.8 In-house 48-158 (343) Show / Hide
Range on Protein: 988-1085
Range on HMM: 48-158/343
Sequence Identity: 30% (34 aa)

LNRPGAPLPYDHSRVVLNHLA--------NAEGLDYVNASTITDH---DPRAPA--YVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARY
||    |||.|||| |..            .. ||.||. .          |   |.|.|.|||||.  |...| . .  ||..|  ..|..   | |||
knrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyrY

WPEEGAEVYHI
.| . . ... 
Wqegsydditv

Phosphatase ia2.AA Subfamily.N_Nematode_egg.PD 998-1218 21 3.7e-11 34.0 In-house 39-252 (257) Show / Hide
Range on Protein: 998-1218
Range on HMM: 39-252/257
Sequence Identity: 21% (48 aa)

DHSRVVLNHLANAEGLDYVNASTITDhDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENgeVACARYWPEEGAEVYHIYEVHLVSEHIWC
. ||| |.        |.. |  .   .|    .. || ||  |   ||.|....    || |   .|.    |  |||.|   .    |  | .  |. 
essrvklelrrGqylddfihanrvkG-kpllnefilaqaplkntvedfwrmvfqekvqyivmltsakes--erceyywpkaeseslvtvpGslrienlkv

DDYLVRSFYLKNLRTSETRtvTQFHFLSwpHMGVPAQAKALLDFRRKVNKSYRgRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGA-REIDIAATLEH
    | . .|.   .    .  ||   |     .  . . .  .| .  | . | |.||.   |  .... . ... | .. .|      .  .   || 
dskadplfrvtklklvGgd--deelfle--hwqgdvnylsdvysplrvlrklr-nlskpvvvqdilGvskaatlvaieiallsllrGpitkslvlravvf

LRDQRAGVVATRQQFEFVLMAV
.|   | .  .. ||   |   
lrlrrrlsvesvllylfvyrlv

Phosphatase ia2.AA Subfamily.N_Nematode_eak.PD 994-1141 21 7.2e-11 33.0 In-house 35-178 (281) Show / Hide
Range on Protein: 994-1141
Range on HMM: 35-178/281
Sequence Identity: 21% (32 aa)

PLPYDHSRVVLNHlANAEGLDYVNASTItDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEV-YHIYEVHLVS
.|.|.  | |   .  . . |.||| . .       |. .  .  . .  ||||. || .  || |    |..     .|.|... .. | |..|.  . 
ivpqdrylvrlts-sqlnrdGyinasla-efsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdktevlkyGildverke

EHIWCDDYLVRSFYLKnlRTSETRTVTQFHFLSWPHMGVPAQaKALLDF
 .  . . .| . |.  .  ||  |  ...  |  . .|   . .| . 
yavkrniletrllilr--kGnethrvlhykvfGwtettlpky-edflal

Phosphatase ia2.AA Subfamily.N_Fungi_PTP1.PD 1113-1217 28 4.3e-10 30.2 In-house 210-337 (343) Show / Hide
Range on Protein: 1113-1217
Range on HMM: 210-337/343
Sequence Identity: 28% (35 aa)

SETRTVTQFHFLSWPHMGVPAQAKALLDFR---------RKVNKSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLE------RMNKGAREIDIA------
||  .| |...  |. ...  . . .|               .. .   || ||.|| ||| ||||... || .|...|  |..| |         .. .
sepyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDl

--ATLEHLRDQRAGVVATRQQFEFVLMA
|| ||  .| . .|| |.  |       
isiivnelrkqrismvqnldqfifiYea

Phosphatase ia2.AA Subfamily.PTPDC1.PD 1120-1214 27 1.4e-07 22.3 In-house 136-220 (229) Show / Hide
Range on Protein: 1120-1214
Range on HMM: 136-220/229
Sequence Identity: 27% (26 aa)

QFHFLSWPHMGVPAQaKALLDFRRKVNKSYrgrRSCPIVVHGSAGAGRTGVYILLDLVLERmnkgarEIDIAATLEHLRDQRAGVVATRQQFEFV
|.  ...  ||..  . .||  . |. .    .   | ||  || ||||| |   ||  .      ... .  .. .|..|.  . ||.| |.| 
yfynfglkDygvasl-eriLdivkvvdfal---eegkiavHCHAGlGRtGvliacylvyak------rltaeeaiklvrskrpksiqtreqvelv

Phosphatase ia2.AA Family.DSP.PD 1115-1220 19 2.5e-07 21.4 In-house 147-245 (387) Show / Hide
Range on Protein: 1115-1220
Range on HMM: 147-245/387
Sequence Identity: 19% (21 aa)

T-RTVTQFHFLSWPHMGVPAQAKAlldFRRKVNKSYRGR-RSCPIVVHGSAGAGRTGVYILLDLVLErmnkgaREIDIAATLEHLRDQRAGVVATRQQFE
| .   ... ..... ..|  ..    | . ..    |.  .  ..||  || ||.|. |   |.        . .   ..|...|..| ||..|.|   
tkelgikylripidDhnapplenl---fekaidfieegndskgvVlVHCkaGkgRsgtliiaYlmks------egltleealdwvrskRpgvitpnqgfl

FVLMAVAE
|..  .  
kqlkdlek

Sequence
Name Sequence Type Origin Length Description Download
ia2.AA Protein None 1319 None Fasta, JSON
ia2.NA RNA None 3957 None Fasta, JSON
ia2.AA.PD_959-1223 Protein Phosphatase Domain None 265 None Fasta, JSON