• Phosphatome.Net

Gene CG15528

CG15528
Species: D.melanogaster
Alias: CG15528
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: DSP14
Protein domain

Protein domains of CG15528.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase CG15528.AA DSPc 28-168 30 2.7e-45 157.69 SMART 1-172 (172) Show / Hide 
Range on Protein: 28-168
Range on HMM: 1-172/172
Sequence Identity: 30% (53 aa)

GLSRITPSLILCGAAAVV---PAYMDKLGVSCVINVAPELP--------------DTPLPSQKNPLYLRIM-AQD-------RSEVDLAKHFDEAADLIE
| |.||| |.|... . .   |. ..|...  ||||..| |                 ...... .|..|   .|         .......|.|..| |.
GPSEITPHLYLGSYPHHMEPNPCFLKKHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFIH

EVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHV-----QAIR-PQVRPNSGFFQQLRRYEQQ
... .||  |.|| ||.||||.|| |||||  .||...|| .|     . .| |...|| .|..||. .|..
DCRQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK
Phosphatase CG15528.AA Subfamily.DSP14.PD 29-168 54 1e-58 188.1 In-house 2-138 (138) Show / Hide 
Range on Protein: 29-168
Range on HMM: 2-138/138
Sequence Identity: 54% (76 aa)

LSRITPSLILCGAAAVVPAYMDKLGVSCVINVAPELPDTPLPSQKnplYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLA
||.||.||.|.||||. .....| ......||..|||.|.|...|   ...|. .|..| .||.||||.|| ||||. .||.||.||||||||||||.||
lseitesLylsgaaalkkeklkkkkitlivnvttelpetkledvk---tvkikveDkpeaklaehfdevadkieevkkkgGktlvhCvaGvsRsAslvla

YLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQ
||||.. .|||||||.|.. ||..|||.||..||..||..
ylmkyeklsLreayklvksaRpiirPnvGFwkqlidyEkk
Phosphatase CG15528.AA DSPc 36-168 34 2.6e-41 145.55 Pfam 1-151 (151) Show / Hide 
Range on Protein: 36-168
Range on HMM: 1-151/151
Sequence Identity: 34% (52 aa)

LILCGAAAVV--PAYMDKLGVSCVINVAPELPDTPLPSQKNPLYLRIM-AQD---------RSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSA
|.|... ..   || ..|.|.. |||.. |.| . ... .. .|..|    |           .......|..| | |. .. .||  |.|| ||.||||
LYLGSYPHHMADPAFLQKHGITHVINCTMECPNNWFYHNSHFHYMWIPHVHDHIHYYHIHWNHCTNISQYFPMATDFIDDCRQKGGKVLVHCQAGISRSA

SLCLAYLMKHAGMSLREAYKHV-----QAIR-PQVRPNSGFFQQLRRYEQQ
.||.|||||  .||..||| .|     .  | |...|| .|  ||. ||.|
CLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ
Phosphatase CG15528.AA Subfamily.DSP10.PD 32-167 38 6.1e-38 120.6 In-house 5-140 (141) Show / Hide 
Range on Protein: 32-167
Range on HMM: 5-140/141
Sequence Identity: 38% (53 aa)

ITPSLILC-GAAAVVPAYMDKLGVSCVINVAPELPDTPlPSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYL
| | |.|  .  |     .|.||...|.||....| .    ..   | || ..| .. .| ..|.|| . |||..  |.  |.|| ||.|||| . .||.
ilpflllGnekdaadkdaldrlgikyvlnvttsvPnff-eekglvrykripvsdsgkqnlkqkfeealefieearkrgsrvlvhchaGisrsatvviayv

MKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQ
||| ..||.|||| |.  || . || .|  || ..|.
mkhlslslseaykfvkekrPiisPnlnfmGqllefek
Phosphatase CG15528.AA Subfamily.DSP19.PD 32-167 38 6.7e-35 110.7 In-house 5-138 (139) Show / Hide 
Range on Protein: 32-167
Range on HMM: 5-138/139
Sequence Identity: 38% (53 aa)

ITPSLILCGA-AAVVPAYMDKLGVSCVINVAPELPDTpLPSQKNplYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYL
..| | |    .|     ..||..  ..||| ..|..  |.. .  |. |   | .|..| ....|| | |||.. ..|. |.|| ||||||||. .|||
vkprlylgsqdvaadkeilkklkitHilnvavgvpnv-fpkdft--yksieilDlpetkllsylkealdFieearskdgrvlvHCnAGvSRsasvviayl

MKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQ
||.  .||..|...|.. || ..||.||..||..||.
mkdeelslekalekvrearpcikPneGFikqLkeyea
Phosphatase CG15528.AA Subfamily.DSP12.PD 30-167 38 1.3e-34 110.1 In-house 3-140 (143) Show / Hide 
Range on Protein: 30-167
Range on HMM: 3-140/143
Sequence Identity: 38% (53 aa)

SRITPSLILCGAAAVV-PAYMDKLGVSCVINVAPELPdTPLPSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLA
|.|.| | | |..||. .. ...| .. |. |. |   . |  .|.  .. | . |. | || .|.||| . |||    .|  |.|| ||||||.....|
seilpglylggleavqerellkelkithvlsvikeel-pelqkekgvkskliqilDepeedlLshldeavrFieeglekegavlvHClagvSRSvtiviA

YLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQ
||||. ..||..|.| |........||.|| .||. .|.
YlmkkeklslekAlklvkekkkeiepNegFleQLklfek
Phosphatase CG15528.AA Family.DSP.PD 29-190 32 4.6e-34 109.1 In-house 107-268 (387) Show / Hide 
Range on Protein: 29-190
Range on HMM: 107-268/387
Sequence Identity: 32% (54 aa)

LSRITPSLILCGAAAV--VPAYmDKLGVSCVINVApelP--DTplPS-QKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSA
|.|.|.|.| .. |.   ..   .|||. ..|..      .    . ...  ||||.  | .. .|...|..| | |||.. |.|. |.|| ||..||..
pseilphlylgsllaaknlewl-kelgvtkivnlt---ddkpq--ftkelgikylripidDhnapplenlfekaidfieegndskgvVlVHCkaGkgRsg

SLCLAYLMKHAGMSLREAYKHVQAIRP-QVRPNSGFFQQLRRYEQQLRGSSSVAMVYFASLDKEIPDI
|. |||||. |..| ||...|.  || ...||.||..|| ..|....  ||  |..  .  . .... 
tliiaYlmksegltleealdwvrskRpgvitpnqgflkqlkdlekeklkvssevmelrfvissivqnl
Phosphatase CG15528.AA Subfamily.DSP1.PD 30-168 36 1.7e-33 106.3 In-house 3-139 (139) Show / Hide 
Range on Protein: 30-168
Range on HMM: 3-139/139
Sequence Identity: 36% (51 aa)

SRITPSLILCGAA-AVVPAYMDKLGVSCVINVAPELPDTplpSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLA
..| . | | .|  |   . ...|... ..||. |||..    ..   | .|. .|....|. ..|.||.| |..|. .||  |.|| ||.||||...||
veildfLyLGsaehasnlqlLkelkitallnvsaelpnv---feelfkyksipvednkkadisslfeeaidfidsvkkkgGrvlvhCqaGisrsativla

YLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQ
||||.  ..|.||...|.  |  . || || .|| ..|.|
yLmkekkvrleeafefvkqrrsiisPnfgfvgqLlefekq
Phosphatase CG15528.AA Subfamily.DSP6.PD 32-168 36 3.1e-33 105.2 In-house 5-141 (141) Show / Hide 
Range on Protein: 32-168
Range on HMM: 5-141/141
Sequence Identity: 36% (50 aa)

ITPSLILCGA-AAVVPAYMDKLGVSCVINVAPELPDTpLPSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYL
|.| | |  | .|     ..||... |.||...||..   ....  |..| ..|. . .|||.| || ..|.| . .    |.|| ||||||...|||||
ilpllylGsakdasnlevlkklkikyvlnvtsnlpnk-feesgelkykqipiedhlsqnlakffPeaiefidearskkskvlvhclaGvsrsvtvtlayl

MKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQ
|.  .|| .||. |.. .... ||  |..||  .|.. 
mkklalslndaydlvkkkksnisPnfnfmgqlldfers
Phosphatase CG15528.AA Subfamily.DSP8.PD 29-169 38 5.4e-32 101.5 In-house 2-142 (143) Show / Hide 
Range on Protein: 29-169
Range on HMM: 2-142/143
Sequence Identity: 38% (54 aa)

LSRITPSLILCGAAAVV-PAYMDKLGVSCVINVAPELPDTPlPSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCL
. ||.| | |     ..    ..|||.| |.|.. . | ..   .|.  .|||  .|. | .|  .||.| . |. .. . |. |.|| ||||||.. .|
ptrilpnlylGsqkdsldeellkklgisyvlnisescpkdv-ellkesrflriPvkDkyeekllpwfdkalefidkarsangkvlvhclaGisrsatvai

AYLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQQL
|.||.  ||| |||..|.  || . ||  | .||  ||..| 
ayimktlemsldeayrfvkekrptispnlnflgqLleyekel
Phosphatase CG15528.AA Subfamily.DSP15.PD 66-167 41 1.1e-28 90.6 In-house 36-137 (138) Show / Hide 
Range on Protein: 66-167
Range on HMM: 36-137/138
Sequence Identity: 41% (42 aa)

DTPLPSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRY
|.. |  ..  ||.|.|.|  ..|| |.|.|. |.| .. | ||  |.||.||.||| .|. ||.|  . .| ..| | |.| |.   |||| .||. .|
dsakplledikylcikaadsPdqdlskffkesidfihkcrleggnvlvhclaGisrsvtlvvayimtvtelswedalkavkaarsvanPnvGfrrqlqef

EQ
. 
ek
Phosphatase CG15528.AA Subfamily.DSP3.PD 47-167 38 6e-28 88.3 In-house 21-147 (148) Show / Hide 
Range on Protein: 47-167
Range on HMM: 21-147/148
Sequence Identity: 38% (49 aa)

AYMDKLGVSCVINVAPELP------DTPLPSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEV-HLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLR
.. |||.  |.| | .        |.   .. .  || . ..|  |.|| |.|.|||| |.|  . ..|  |.|||.|.|||| | |||||.  ..|.||
ekLkklGithvLnaaegkrllkvdtdaefYkdleikylGvevsDvpefdlskyfeeaadfidealsqkngkvlvhcvvGisRsatlvlayLmirrkltlk

EAYKHVQAIRpQVRPNSGFFQQLRRYEQ
 |.|.  | .. ||.||..||.....  
eaiktvrkkr-eilPneGflkqLlelde
Phosphatase CG15528.AA Subfamily.LRR-DSP.PD 36-167 38 2.5e-27 86.1 In-house 9-136 (137) Show / Hide 
Range on Protein: 36-167
Range on HMM: 9-136/137
Sequence Identity: 38% (51 aa)

LIL-CGAAAVVPAYMDKLGVSCVINVAPELPDTPlpsqKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGcTLIHCVAGVSRSASLCLAYLMKHA
| | |  .|   ... ...|. .. ||   |  |    .   || | ..|  |.|. .||.|   .|.|   .||  |||| |||||||.| .|||||. 
lylgcresamnksilkdnnvthilavadfkplyp----dlfkyliidiedvdeadiyqhfkemnafidegrekgg-vlihcragvsrsatlviaylmkkn

GMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQ
 . ..||.  |.  ||...|| || .||...|.
slkfkealdlvikkrpriypnrgfldqlkkfek
Phosphatase CG15528.AA Subfamily.Slingshot.PD 50-166 40 6.4e-27 84.8 In-house 24-137 (139) Show / Hide 
Range on Protein: 50-166
Range on HMM: 24-137/139
Sequence Identity: 40% (47 aa)

DKLGVSCVINVAPELPDTpLPSQKNplYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIR
. ||. ..||. |. .   | . .  ||.|   | .| || ||..|. . ||... .|   |.||  |||||||  .|| ||. ..|| ||...|.  | 
kengveyilnvtkeidnf-fpekfk--ylnirvydeeetdllkhwnetykfiekakekgskvlvhckmGvsrsastviayamkeyelsleealeyvkerr

PQVRPNSGFFQQLRRYE
 ..||.||..||. || 
siikpnkgflkqlkvye
Phosphatase CG15528.AA Subfamily.STYXL1.PD 43-168 31 3.8e-23 73.0 In-house 18-143 (143) Show / Hide 
Range on Protein: 43-168
Range on HMM: 18-143/143
Sequence Identity: 31% (39 aa)

AVVPAYMDKLGVSCVINVAPELPDTPLPSQKNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAY
|. ||    | |  ..||. .  .     ..    |.|  .| .| || ....|. ..||. . .| . |.    |.||||.. .||||.  ..|..|||
aqnpaikkdlkvkahvnvssdaekliagladvakllhiavedeneadllerlkevvqfiekhkkegevvlvfsnkGisrsaaviiaylmyskkitlkkay

KHVQAIRPQVRPNSGFFQQLRRYEQQ
...  .. |.|| .| .||...|.| 
kylkkckenvkPnrafveqlseWekq
Phosphatase CG15528.AA Subfamily.STYX.PD 73-166 35 8.8e-21 65.0 In-house 51-144 (146) Show / Hide 
Range on Protein: 73-166
Range on HMM: 51-144/146
Sequence Identity: 35% (33 aa)

KNPLYLRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYE
.. .|| .   | .  .. ... .. ..|..   .||  |.|  ||.||||.| .||.|.  |.  |||...||  |  . ||.|| .||.|| 
drfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaalviayimetyglkyreafayvqerrfcinpnegfvsqlkeye
Phosphatase CG15528.AA Subfamily.PTPMT1.PD 78-167 33 1.8e-17 54.2 In-house 56-145 (146) Show / Hide 
Range on Protein: 78-167
Range on HMM: 56-145/146
Sequence Identity: 33% (30 aa)

LRIMAQDRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQLRRYEQ
|..   |  |.   ..  |. ..||.|.  | .  .|| || .|||.|  .||||.  .|  || |.....|||.| .|  .. |.....
lqlatvDfteapslekleegvefiekvaskgssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpqirlkskqwralqefke
Phosphatase CG15528.AA Subfamily.CDC14.PD 106-151 31 3.6e-09 27.4 In-house 196-241 (258) Show / Hide 
Range on Protein: 106-151
Range on HMM: 196-241/258
Sequence Identity: 31% (14 aa)

LSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPQ
. |   .|| ||. | ..|  .||.|| ...  |.  ... .||  
kaeGaiavhCkaGLGrtgtligcylikhyrftaaetiawlriarPG
Phosphatase CG15528.AA Subfamily.DSP23.PD 94-151 25 3.7e-07 21.0 In-house 52-109 (128) Show / Hide 
Range on Protein: 94-151
Range on HMM: 52-109/128
Sequence Identity: 25% (14 aa)

FDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPQ
..   ..|| . ...   .||. |. |. .|   ||.|. |..  .|   |.  |.  
varlvriveeaekkeeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrrkG
Phosphatase CG15528.AA Subfamily.PTPDC1.PD 105-152 34 1.3e-06 18.7 In-house 163-210 (229) Show / Hide 
Range on Protein: 105-152
Range on HMM: 163-210/229
Sequence Identity: 34% (16 aa)

HLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPQV
|. | . .|| ||  |  .|  .||. .  ..  || | |.. ||.  
aleegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrpks
Phosphatase CG15528.AA Subfamily.DSP11.PD 88-162 22 1.4e-06 18.9 In-house 60-135 (141) Show / Hide 
Range on Protein: 88-162
Range on HMM: 60-135/141
Sequence Identity: 22% (17 aa)

VDLAKHFDE-AADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPQVRPNSGFFQQL
. .|.| |   . .|. . ..    .||  || |.  |   ||... |.|  .| .  . .|        . ..| 
kedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyspedaieafeearGhslerenyledL
Phosphatase CG15528.AA Subfamily.R_Nematode_3.PD 93-130 39 1.9e-06 18.1 In-house 183-220 (267) Show / Hide 
Range on Protein: 93-130
Range on HMM: 183-220/267
Sequence Identity: 39% (15 aa)

HFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYL
. .|| .||. |. |    ..||..|.||||.|  . |
epkealelikfveksktpvvVHCsdGisRsatlaaiel
Phosphatase CG15528.AA Subfamily.Laforin.PD 84-152 28 3.4e-06 17.6 In-house 80-148 (165) Show / Hide 
Range on Protein: 84-152
Range on HMM: 80-148/165
Sequence Identity: 28% (20 aa)

DRSEVDLAKHFDEAADLIEEVHLSGGCTLIHCVAGVSRSASLCLAYLMKHAGMSLREAYKHVQAIRPQV
| |     . . .|  |.  .   |    .|| ||| ||...   .|.   | ||.    .. | || |
dlstesrvenlpqavyllhallekghivyvhcnagvgrstaivcgflqyvlgwslakvqyfllakrpvv
Phosphatase CG15528.AA Subfamily.N_Nematode_1.PD 98-153 31 5.1e-06 16.7 In-house 186-243 (265) Show / Hide 
Range on Protein: 98-153
Range on HMM: 186-243/265
Sequence Identity: 31% (18 aa)

ADLIEEVHLSGGCTLIHCVAGVSRSASL-CLAYLMKH--AGMSLREAYKHVQAIRPQvR
.|.|.|. | | ...|| ||. |. ..  ..|.. .  .| ..... | |..|| | | 
lelleavrgskgPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireq-r
Phosphatase CG15528.AA Subfamily.PRL.PD 108-165 29 8.7e-06 16.3 In-house 81-136 (140) Show / Hide 
Range on Protein: 108-165
Range on HMM: 81-136/140
Sequence Identity: 29% (17 aa)

GGCTLIHCVAGVSRSASLCLAYLMkHAGMSLREAYKHVQAIRPQvRPNSGFFQQLRRY
. .  .|||||. |.  |    |.  |||. ..| . ..  |     ||  .. |..|
kstvavhcvaGlGraPvlvalali-eaGmkyedavefirekrrg-ainskqlkfleky
Sequence
Name Sequence Type Origin Length Description Download
CG15528.AA Protein None 212 None Fasta, JSON
CG15528.NA RNA None 636 None Fasta, JSON
CG15528.AA.PD_28-168 Protein Phosphatase Domain None 141 None Fasta, JSON