• Phosphatome.Net

Gene CG10089

CG10089
Species: D.melanogaster
Alias: CG10089
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: DSP15
Protein domain

Protein domains of CG10089.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase CG10089.AA Family.DSP.PD 3-161 30 7.5e-35 111.8 In-house 105-267 (387) Show / Hide 
Range on Protein: 3-161
Range on HMM: 105-267/387
Sequence Identity: 30% (51 aa)

NGMNKVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSPRRllPDK----HYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTV
......||.||.|. .. |.. .|.. ....|. . | . .   .|    .||... .|.. ..|...|  . |||. ..  .|.||.|| || .|| |.
gkpseilphlylgsllaaknlewlkelgvtkivnltddkpq--ftkelgikylripidDhnapplenlfekaidfieegndskgvVlVHCkaGkgRsgtl

AVAYIMTATHLNWKEALKVVRAGRA-VANPNAGFQSQLQEFEQFKLSEERRRLRERFPSS-ALEQ
 .||.| . .|. .|||. ||  |  |..|| || .||...|. ||..... .  ||  |   ..
iiaYlmksegltleealdwvrskRpgvitpnqgflkqlkdlekeklkvssevmelrfvissivqn
Phosphatase CG10089.AA Subfamily.DSP15.PD 4-140 65 9.6e-76 243.2 In-house 1-137 (138) Show / Hide 
Range on Protein: 4-140
Range on HMM: 1-137/138
Sequence Identity: 65% (90 aa)

GMNKVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSPRRLLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYI
|||||||||||||.||.||..|||..||.||..||||...||.|..|||..|.|.|||.||..|....||||..||..||||.|||||.|||||..||||
gmnkvlpGlyvGnfrdakdkeqleenkithilsihdsakplledikylcikaadsPdqdlskffkesidfihkcrleggnvlvhclaGisrsvtlvvayi

MTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
||.|.|.|..|||.|.|.|.|||||.||..||||||.
mtvtelswedalkavkaarsvanPnvGfrrqlqefek
Phosphatase CG10089.AA DSPc 4-141 26 2.2e-45 158.01 SMART 1-172 (172) Show / Hide 
Range on Protein: 4-141
Range on HMM: 1-172/172
Sequence Identity: 26% (46 aa)

GMNKVLPGLYVGNYRDSK--DHAQLERFKISHIIAIHDSPR------------------RLLPDKHYLCVM-ASD-------TPDQNLSQYFSVCNDFIH
|. ...|.||.|.|...   . ..|. ..| |.|   .. .                  .  ....|...   .|       .. .|.||||. ..||||
GPSEITPHLYLGSYPHHMEPNPCFLKKHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFIH

AARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVV-----RAGR-AVANPNAGFQSQLQEFEQF
..| . |.||.||.|| |||.|...||.|   .... .|.  |     .  |    .||..|. ||.|.|..
DCRQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK
Phosphatase CG10089.AA DSPc 12-141 31 3.8e-40 141.52 Pfam 1-151 (151) Show / Hide 
Range on Protein: 12-141
Range on HMM: 1-151/151
Sequence Identity: 31% (47 aa)

LYVGNYRDSK-DHAQLERFKISHII-AIHDSPR---RLLPDKHYLCVM-ASD---------TPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSV
||.|.| ... | |.|. ..|.|.| ..   |    .  ...||...    |         ....|.||||. . |||...| . |.||.||.|| |||.
LYLGSYPHHMADPAFLQKHGITHVINCTMECPNNWFYHNSHFHYMWIPHVHDHIHYYHIHWNHCTNISQYFPMATDFIDDCRQKGGKVLVHCQAGISRSA

TVAVAYIMTATHLNWKEALKVV-----RAGR-AVANPNAGFQSQLQEFEQF
....||.|   ... .||.  |     .  |  . .||..|. ||.|.|..
CLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ
Phosphatase CG10089.AA Subfamily.DSP12.PD 5-141 32 7.4e-38 120.7 In-house 2-141 (143) Show / Hide 
Range on Protein: 5-141
Range on HMM: 2-141/143
Sequence Identity: 32% (45 aa)

MNKVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSPR---RLLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVA
....|||||.|. .. .....|. .||.|....   .    .  ...... . . |.|...| ...  ...||. .. .||.||.|||||.|||||. .|
vseilpglylggleavqerellkelkithvlsvikeelpelqkekgvkskliqilDepeedlLshldeavrFieeglekegavlvHClagvSRSvtiviA

YIMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQF
|.|  ..|. ..|||.|.. .  ..||.||..||. ||. 
YlmkkeklslekAlklvkekkkeiepNegFleQLklfekm
Phosphatase CG10089.AA Subfamily.DSP19.PD 6-140 37 1.3e-37 119.6 In-house 3-138 (139) Show / Hide 
Range on Protein: 6-140
Range on HMM: 3-138/139
Sequence Identity: 37% (51 aa)

NKVLPGLYVGNYRDSKDHAQLERFKISHIIAIH-DSPRRLLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIM
.| | ||.|     .|. .|.. || ||. .  . |.    | .|...   |.|...| .|.. . |||. || ..| ||.|| ||.|||..|..||.|.
aevkprlylgsqdvaadkeilkklkitHilnvavgvpnvfpkdftyksieilDlpetkllsylkealdFieearskdgrvlvHCnAGvSRsasvviaylm

TATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
 ..|. ..||..||. |  ..||.||. ||.|.|. 
kdeelslekalekvrearpcikPneGFikqLkeyea
Phosphatase CG10089.AA Subfamily.DSP10.PD 5-140 37 7.4e-35 110.7 In-house 2-140 (141) Show / Hide 
Range on Protein: 5-140
Range on HMM: 2-140/141
Sequence Identity: 37% (52 aa)

MNKVLPGLYVGNYRDSKDHAQLERFKISHIIAIHD-SPRRLL--PDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVA
. ..|| |..|| .|..|.  |.|. |.... .   .|       ...|  . .||.. |||.|.|.   .||. || |...||.|| ||.|||.||..|
assilpflllGnekdaadkdaldrlgikyvlnvttsvPnffeekglvrykripvsdsgkqnlkqkfeealefieearkrgsrvlvhchaGisrsatvvia

YIMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
|.|  ..|  .|| |.|.  | .  || .|  || |||.
yvmkhlslslseaykfvkekrPiisPnlnfmGqllefek
Phosphatase CG10089.AA Subfamily.DSP6.PD 7-140 33 2.1e-33 105.8 In-house 4-140 (141) Show / Hide 
Range on Protein: 7-140
Range on HMM: 4-140/141
Sequence Identity: 33% (46 aa)

KVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDS-PRRLL--PDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYI
..|| ||.|. .|...   |...||.... . .  |      .. .|. . ..|.  |||...|    .||  || .. .||.|||||.||||||..||.
eilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkykqipiedhlsqnlakffPeaiefidearskkskvlvhclaGvsrsvtvtlayl

MTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
|  ..|  ..| ..|.. ..   ||  |  || .||.
mkklalslndaydlvkkkksnisPnfnfmgqlldfer
Phosphatase CG10089.AA Subfamily.DSP1.PD 6-140 30 4.2e-33 105.2 In-house 3-138 (139) Show / Hide 
Range on Protein: 6-140
Range on HMM: 3-138/139
Sequence Identity: 30% (41 aa)

NKVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSPRRL-LPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIM
...|. ||.|   .. ....|.. ||.... .  .         .| ... .|......|..|.  .|||.... ..| ||.|| ||.||||. .||.|.
veildfLyLGsaehasnlqlLkelkitallnvsaelpnvfeelfkyksipvednkkadisslfeeaidfidsvkkkgGrvlvhCqaGisrsativlayLm

TATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
 .... .|| . |.  |.. .|| ||  || |||. 
kekkvrleeafefvkqrrsiisPnfgfvgqLlefek
Phosphatase CG10089.AA Subfamily.DSP14.PD 5-140 29 3.8e-32 102.1 In-house 2-137 (138) Show / Hide 
Range on Protein: 5-140
Range on HMM: 2-137/138
Sequence Identity: 29% (40 aa)

MNKVLPGLYVGnYRDSKDHAQLERFKISHIIAI-HDSPRRLLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYI
.... . ||..  .  .....|.. ||..|. .  . |   |.| ... .. .|.|...|...| .  | |.... ..|..|.|| ||.||| ....||.
lseitesLyls-gaaalkkeklkkkkitlivnvttelpetkledvktvkikveDkpeaklaehfdevadkieevkkkgGktlvhCvaGvsRsAslvlayl

MTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
|   .|. .|| |.|.. |.. .|| || .||...|.
mkyeklsLreayklvksaRpiirPnvGFwkqlidyEk
Phosphatase CG10089.AA Subfamily.LRR-DSP.PD 7-140 37 8.1e-32 100.8 In-house 4-136 (137) Show / Hide 
Range on Protein: 7-140
Range on HMM: 4-136/137
Sequence Identity: 37% (50 aa)

KVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSpRRLLPDK-HYLCVMASDTPDQNLSQYFSVCNDFIHAARlREGNVLIHCLAGMSRSVTVAVAYIMT
.....||.|    ..... |.  ...||.|. |  . | ||  .|| . ..|... ...|.|   | ||.  | ..| ||||| ||.||| |...||.| 
liidklylgcresamnksilkdnnvthilavadf-kplypdlfkyliidiedvdeadiyqhfkemnafidegr-ekggvlihcragvsrsatlviaylmk

ATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
  .|..|||| .|  .|.  .|| ||. ||. ||.
knslkfkealdlvikkrpriypnrgfldqlkkfek
Phosphatase CG10089.AA Subfamily.DSP8.PD 5-140 38 6.4e-31 98.1 In-house 2-140 (143) Show / Hide 
Range on Protein: 5-140
Range on HMM: 2-140/143
Sequence Identity: 38% (53 aa)

MNKVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDS-PR--RLLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVA
....|| ||.|  .|| |.  |..  ||... |  | |    ||.....| .   |. . .|...|  . .||  ||  .|.||.|||||.||| |||.|
ptrilpnlylGsqkdsldeellkklgisyvlnisescpkdvellkesrflriPvkDkyeekllpwfdkalefidkarsangkvlvhclaGisrsatvaia

YIMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
|||   ...  || . |.  |.  .||  |  || |.|.
yimktlemsldeayrfvkekrptispnlnflgqLleyek
Phosphatase CG10089.AA Subfamily.DSP3.PD 5-139 36 2.4e-30 96.2 In-house 2-146 (148) Show / Hide 
Range on Protein: 5-139
Range on HMM: 2-146/148
Sequence Identity: 36% (54 aa)

MNKVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSPR--------RLLPD--KHYLCVMASDTPDQNLSQYFSVCNDFIHAARLR-EGNVLIHCLAGMS
.. | |..|||.   .||. .|... | |..   .. |            |   .|| | .||.|. .||.||.   |||. |  . .| ||.|| .|.|
vdevypkvyvgdeavakdkekLkklGithvLnaaegkrllkvdtdaefYkdleikylGvevsDvpefdlskyfeeaadfidealsqkngkvlvhcvvGis

RSVTVAVAYIMTATHLNWKEALKVVRAGRAVaNPNAGFQSQLQEFE
|| |...||.|   .|. |||.| ||  |..  || || .|| |..
RsatlvlayLmirrkltlkeaiktvrkkrei-lPneGflkqLleld
Phosphatase CG10089.AA Subfamily.Slingshot.PD 7-139 29 1.3e-24 77.4 In-house 4-137 (139) Show / Hide 
Range on Protein: 7-139
Range on HMM: 4-137/139
Sequence Identity: 29% (39 aa)

KVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSPRRLLPDK-HYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMT
|.   ||.|   .. .  .|.. ....|. .        |.| .|| .   |.....| ...    .||..|. .. .||.||  |.||| .. .|| | 
kifdhlylGsewnasnleelkengveyilnvtkeidnffpekfkylnirvydeeetdllkhwnetykfiekakekgskvlvhckmGvsrsastviayamk

ATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFE
. .|. .|||. |.  | ...||.|| .||...|
eyelsleealeyvkerrsiikpnkgflkqlkvye
Phosphatase CG10089.AA Subfamily.STYX.PD 5-140 34 3.9e-24 76.0 In-house 2-145 (146) Show / Hide 
Range on Protein: 5-140
Range on HMM: 2-145/146
Sequence Identity: 34% (49 aa)

MNKVLPGLYVGNYRDSKD--HAQLERFKISHIIAIHDSPRRL-----LPD-KHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSV
|...||||..| |  ..     .|..  |.||. | ...        .||  .|| .  .|.. .|. .|.   ..||  .  . |.||.|||.||| ..
mqeilpglflgpysaamksklevlkehgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsa

TVAVAYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
 .|||| .  |...|| . |.  | . |||.|| |||.|.|   
alviayimetyglkyreafayvqerrfcinpnegfvsqlkeyea
Phosphatase CG10089.AA Subfamily.STYXL1.PD 8-140 27 4.4e-20 63.2 In-house 5-142 (143) Show / Hide 
Range on Protein: 8-140
Range on HMM: 5-142/143
Sequence Identity: 27% (38 aa)

VLPG-LYVGNYRDSKDHAQLERFKISHIIAIHDSPRRLL---PD-KHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAY
|||| ||.|||..... |  . .|.   . .     .|.   .|  . | .  .|... .| . ..   .||.  . ..  ||.    |.|||..|..||
vlPgklylGnykqaqnpaikkdlkvkahvnvssdaekliagladvakllhiavedeneadllerlkevvqfiekhkkegevvlvfsnkGisrsaaviiay

IMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
.|   ... |.|.| ..  .   .|| .| .||.|.|.
lmyskkitlkkaykylkkckenvkPnrafveqlseWek
Phosphatase CG10089.AA Subfamily.PTPMT1.PD 66-140 28 9.9e-12 35.7 In-house 71-145 (146) Show / Hide 
Range on Protein: 66-140
Range on HMM: 71-145/146
Sequence Identity: 28% (21 aa)

YFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
. .   .||.  . .. .| .|| || .|| |.. .|.|. ..|. .|| |.... |     .    . ||||..
kleegvefiekvaskgssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpqirlkskqwralqefke
Phosphatase CG10089.AA Subfamily.CDC14.PD 69-124 23 8.6e-09 26.2 In-house 186-244 (258) Show / Hide 
Range on Protein: 69-124
Range on HMM: 186-244/258
Sequence Identity: 23% (14 aa)

VCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEA---LKVVRAGRAV
. . |....   ||.. .|| ||. |  |.  .|..   ... .|.   |...| |  .
ilkkfleitekaeGaiavhCkaGLGrtgtligcylikhyrftaaetiawlriarPGsvi
Phosphatase CG10089.AA Subfamily.PTPDC1.PD 77-141 31 9.6e-09 25.8 In-house 162-226 (229) Show / Hide 
Range on Protein: 77-141
Range on HMM: 162-226/229
Sequence Identity: 31% (20 aa)

ARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQF
|.||.. .|| ||. |   .  .|.. |..|. .||.|.||. |. .    .    ..||..|  
faleegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrpksiqtreqvelveeFalf
Phosphatase CG10089.AA Subfamily.DSP23.PD 73-123 28 7.7e-07 20.1 In-house 58-108 (128) Show / Hide 
Range on Protein: 73-123
Range on HMM: 58-108/128
Sequence Identity: 28% (14 aa)

FIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRA
.. |  .|. | .||. |. |. |.   |..    |  ..|.  ||  |  
iveeaekkeeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrrk
Phosphatase CG10089.AA Subfamily.PRL.PD 59-126 23 9.9e-07 19.5 In-house 61-125 (140) Show / Hide 
Range on Protein: 59-126
Range on HMM: 61-125/140
Sequence Identity: 23% (16 aa)

PDQNLSQYFSVCNDFIHAArlREGNVLIHCLAGMSRS-VTVAVAYImtATHLNWKEALKVVRAGRAVAN
|.. . ........  . .   .  | .||.||. |. | ||.| |   . .. ..|....|  |  | 
pkevvdeWlellkekfkee--pkstvavhcvaGlGraPvlvalali--eaGmkyedavefirekrrgai
Phosphatase CG10089.AA Subfamily.R_Nematode_3.PD 69-125 28 1.6e-06 18.5 In-house 186-248 (267) Show / Hide 
Range on Protein: 69-125
Range on HMM: 186-248/267
Sequence Identity: 28% (17 aa)

VCNDFIHAARLREGNVLIHCLAGMSRSVTVAV---AYIMT--AT-HLNWKEALKVVRAGRAVA
. |....  . .|..|| .|.||| | |.   .| .    . .|.  . .| .|. || |   
ealelikfveksktpvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRaga
Sequence
Name Sequence Type Origin Length Description Download
CG10089.AA Protein None 327 None Fasta, JSON
CG10089.NA RNA None 981 None Fasta, JSON
CG10089.AA.PD_4-150 Protein Phosphatase Domain None 147 None Fasta, JSON