• Phosphatome.Net

Gene mRNA-capping-enzyme

mRNA-capping-enzyme
Species: D.melanogaster
Alias: mRNA-capping-enzyme
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: RNGTT
Protein domain

Protein domains of mRNA-capping-enzyme.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase mRNA-capping-enzyme.AA Subfamily.CDC14.PD 27-174 29 3.2e-16 50.3 In-house 108-243 (258) Show / Hide 
Range on Protein: 27-174
Range on HMM: 108-243/258
Sequence Identity: 29% (44 aa)

DTIIAERFLAFKTPLSNNFHDKMPieCTFQPEMLFEYCKTLKVKLglWVDLtNtKRFYDRSAVEELGAKYIKLQCRgHGETPSPEQTHSFIEIVDNFine
||| ..|.|.  |  .. ...     . .|| |.|| . ..|.    | | | |. ||..  .. | ..  |     | .||..  ..|.||...     
ttiipnkfialagphnkskvedGy--tllaPeklleyfrknnvtt--ivrL-n-kklYdakkftdaGfahlDlffi-DGtvPsdailkkfleiteka---

rpFDVIAVHCTHGFNRTGFLIVCYLVERLDCSVSAALAIFASARPPGI
    |||||  |  ||| || |||. .   . . ..| .  |||  . 
--eGaiavhCkaGLGrtgtligcylikhyrftaaetiawlriarPGsv
MRNA_cap_enzyme mRNA-capping-enzyme.AA mRNA_cap_enzyme 307-497 42 1.8e-152 365.33 Pfam 1-213 (213) Show / Hide 
Range on Protein: 307-497
Range on HMM: 1-213/213
Sequence Identity: 42% (91 aa)

QPVSMDR-ENIKRLSEIPYRVSWKADGTRYMMLIDGRDE------VYFFDRNHSCFQVENVTFVESRN-----LNEHLDGTLVDGEMVLDKIGET----V
|||||.| ||.|.|.. .|.|.||.||.||||.|....|      .|..||......|||..|....|     |..|...||.||||..|.| ..    .
QPVSMSRRENMKFLKQNYYYVCWKTDGMRYMMFITDHPEYGEFKGCYMIDRDMNYYHVENMRFPCKYNKWGESLDKHHHYTLLDGEMCIDTIPMQETQCQ

TPRYLIYDIVRLSNRD-VRDEPFYP-NRLDYIKTEVIGPRILGM--KHGIINQRLQAFSVRGKDFWDIWMSARLL--GEKFSRTLAHEPDGLIFQPSKQP
.|||||||.|...... |...|||. .|...||.|.|.||.  |  |..........|||| ||.||.|.|..|.  ..|| ..|.||.||||||....|
QPRYLIYDCVAINGQCRVMQWPFYSRKRWEMIKREIIKPRNHNMKFKTHWYRYDMFPFSVRFKDMWDNWHSEKLVYYFHKFIPHLCHEIDGLIFQCWDTP

YTAGTCSDVFKWK
|..|.|...||||
YVPGRCQNLFKWK
Phosphatase mRNA-capping-enzyme.AA Subfamily.RNGTT.PD 52-189 66 9.3e-72 229.8 In-house 2-139 (140) Show / Hide 
Range on Protein: 52-189
Range on HMM: 2-139/140
Sequence Identity: 66% (92 aa)

ECTFQPEMLFEYCKTLKVKLGLWVDLTNTKRFYDRSAVEELGAKYIKLQCRGHGETPSPEQTHSFIEIVDNFINERPFDVIAVHCTHGFNRTGFLIVCYL
|..|.||||..|.|||||||||..|||||.|.||....|. |.|||||||||.||.|..|||..||..|..|....| .||.|||||||||||||||.||
eeafepemlksylktlkvklglvidltntsryydkeelekegvkyiklqcrGrGeaPtkeqtklfiklvkeflkkkPdevigvhCthGfnrtGflivayL

VERLDCSVSAALAIFASARPPGIYKQDYINELYKRYED
||..|.||.||.|.||.||||||||.||..||.|||||
vekedwsveaavalfakarppGiykedylkelfkryed
Phosphatase mRNA-capping-enzyme.AA Subfamily.DSP11.PD 52-187 41 4.9e-36 114.2 In-house 3-139 (141) Show / Hide 
Range on Protein: 52-187
Range on HMM: 3-139/141
Sequence Identity: 41% (56 aa)

ECTFQPEMLFEYCKTLKVKLGLWVDLTNTKRFYDRSAVEELGAKYIKLQCRGHgETPSPEQTHSFIEIVDNFI--NERPFDVIAVHCTHGFNRTGFLIVC
| .| || |.|  .  . |||| .|||||.|.|....... | || ||.| || |.|. |. ..|.| |..|.  |.    .|.||||||||||.||  |
eerfapedlleklqeknkklGLvidltntdryykkkeltdegvkykklncpGh-evpekedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCr

YLVERLDCSVSAALAIFASARPPGIYKQDYINELYKRY
|... . | . |.  | .||   . ...|...|.|.  
ylidvegyspedaieafeearGhslerenyledLkkla
Phosphatase mRNA-capping-enzyme.AA Family.DSP.PD 74-188 27 4.3e-23 72.8 In-house 136-245 (387) Show / Hide 
Range on Protein: 74-188
Range on HMM: 136-245/387
Sequence Identity: 27% (34 aa)

WVDLTntkrfY------DrsaveELGAKYIKLQCRGHgETPSPEQThsFIEIVDnFINE--RPFDVIAVHCTHGFNRTGFLIVCYLVERLDCSVSAALAI
|.||     .            ||| ||.....  | ..|..|.   |....| ||.|  ..  |..|||..| .|.| ||..||... ... ..||. .
ivnlt-----ddkpqftk-----elgikylripidDh-napplenl--fekaid-fieegndskgvVlVHCkaGkgRsgtliiaYlmksegltleealdw

FASARP-PGIYKQDYINELYKRYE
.|.||   . .| .. .| . .. 
vrskRpgvitpnqgflkqlkdlek
Phosphatase mRNA-capping-enzyme.AA Subfamily.PTEN.PD 107-170 35 5.6e-13 39.4 In-house 72-136 (305) Show / Hide 
Range on Protein: 107-170
Range on HMM: 72-136/305
Sequence Identity: 35% (23 aa)

TPSPEQTHSFIEIVDNFINERPFDVIAVHCTHGFNRTGFLIVCYLVERLDCSVS-AALAIFASAR
|. |  ....| ||....|    |.||||  |  ||| .|..||.... ..    ||||....| 
pptleLleeivedvdkwLkedksnVvavHCkaGkGRtGvmicayLlksgikksadealaiydekR
Phosphatase mRNA-capping-enzyme.AA Subfamily.DSP23.PD 75-175 29 3.9e-12 37.0 In-house 18-112 (128) Show / Hide 
Range on Protein: 75-175
Range on HMM: 18-112/128
Sequence Identity: 29% (28 aa)

VDLTNTKRFYDRsAVEELGAKYIKLQcrgHGETPSPEQTHSFIEIVDNFiNERpFDVIAVHCTHGFNRTGFLIVCYLVERLDCSVSAALAIFASARPPGI
|.||.  . |   |...|. . |...       |..||   ...||..  ...  . ..|||  |. ||| |. ||||.  . . . |.||.  |     
vslttegapyse-aapsltlrridip---dfcPPaleqvarlvriveea-ekk-eeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrrkGsi

Y
 
e
Phosphatase mRNA-capping-enzyme.AA Subfamily.PTPDC1.PD 108-181 33 1.4e-10 31.5 In-house 148-218 (229) Show / Hide 
Range on Protein: 108-181
Range on HMM: 148-218/229
Sequence Identity: 33% (25 aa)

PSPEQTHSFIEIVDNFINErpfDVIAVHCTHGFNRTGFLIVCYLVERLDCSVSAALAIFASARPPGIYKQDYIN
.| |.    . .||  ..|     |||||  |  ||| || ||||   . . . |. .  | ||  |. .. ..
asleriLdivkvvdfalee---gkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrpksiqtreqve
Phosphatase mRNA-capping-enzyme.AA Subfamily.PTPMT1.PD 89-175 25 8.9e-10 29.1 In-house 48-132 (146) Show / Hide 
Range on Protein: 89-175
Range on HMM: 48-132/146
Sequence Identity: 25% (21 aa)

VEELGAKYIKLQCRGHGETPSPEQTHSFIEIVDNFINERpfDVIAVHCTHGFNRTGFLIVCYLVERLDCSVSAALAIFASARPPGIY
..|| ....|    ..|.|| |. .  .|.........  . . |||  |  | . |. |||...  .|   |  .... ||     
wkklGveqlqlatvDfteapslekleegvefiekvaskg--ssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpqirl
Phosphatase mRNA-capping-enzyme.AA Subfamily.PRL.PD 82-154 28 9.4e-08 22.5 In-house 35-106 (140) Show / Hide 
Range on Protein: 82-154
Range on HMM: 35-106/140
Sequence Identity: 28% (20 aa)

RFYDRSAVEELGAKYIKLQCRgHGETPSPEQTHSFIEIVDNFINERPFDVIAVHCTHGFNRTGFLIVCYLVER
|| . ..| | . . |.    | .|. |  ....|.. .  .|.|  ..||||  |. |.  |.   |.|   
psydaeklkeegievldlafd-dGavPpkevvdeWlellkekfkeepkstvavhcvaGlGraPvlvalaliea
Phosphatase mRNA-capping-enzyme.AA Family.OCA.PD 57-149 21 1.4e-07 21.9 In-house 21-112 (165) Show / Hide 
Range on Protein: 57-149
Range on HMM: 21-112/165
Sequence Identity: 21% (20 aa)

PEMLFEYCKTLKVKLGLWVDLTN--TKRFYdrSAVEELGAKYIKLQCRGHGETPSPEQTHSFIEIVDNFINERPFDViAVHCTHGFNRTGFLIVC
|. | . |||| |  ...   .  .. ..  . |||   |.| ... .. .   . . .. ....   .... . |  .||..| .||| .. | 
nelnfsflktLkLktiislspeelpqesll--kfveeeniklihikvdkkkkdlveieeellkrvlkilldvdnypv-lihcnkGkhrtglvvgc
Phosphatase mRNA-capping-enzyme.AA Subfamily.OCA.PD 57-149 21 1.4e-07 21.9 In-house 21-112 (165) Show / Hide 
Range on Protein: 57-149
Range on HMM: 21-112/165
Sequence Identity: 21% (20 aa)

PEMLFEYCKTLKVKLGLWVDLTN--TKRFYdrSAVEELGAKYIKLQCRGHGETPSPEQTHSFIEIVDNFINERPFDViAVHCTHGFNRTGFLIVC
|. | . |||| |  ...   .  .. ..  . |||   |.| ... .. .   . . .. ....   .... . |  .||..| .||| ..|  
nelnfsflktLkLktiislspeelpqesll--kfveeeniklihikvdkkkkdlveieeellkrvlkilldvdnypv-lihcnkGkhrtglvvgc
Phosphatase mRNA-capping-enzyme.AA Subfamily.DSP12.PD 123-183 22 6.5e-07 20.1 In-house 73-135 (143) Show / Hide 
Range on Protein: 123-183
Range on HMM: 73-135/143
Sequence Identity: 22% (14 aa)

FINERP--FDVIAVHCTHGFNRTGFLIVCYLVERLDCSVSAALAIFASARPPGIYKQDYINEL
||.|     . . |||. |  |   ... ||. . ..|.. || .  ....     . ... |
FieeglekegavlvHClagvSRSvtiviAYlmkkeklslekAlklvkekkkeiepNegFleQL
Phosphatase mRNA-capping-enzyme.AA Subfamily.TPIP.PD 108-166 25 9.8e-07 19.2 In-house 16-75 (245) Show / Hide 
Range on Protein: 108-166
Range on HMM: 16-75/245
Sequence Identity: 25% (15 aa)

PSPEQTHSFIEIVDNFINERPFDVIAVHCTHGFNRTGFLIVCYLVERLDCSV-SAALAIF
|  |.  .| . |...... . .|.|.||  | .||| .. ..|..   ..    .|  |
PtleelvvftkevkewlakdlenvvaihckGGkgrtGtivcalliaseifltaeesldyf
Phosphatase mRNA-capping-enzyme.AA Subfamily.DSP19.PD 116-183 25 1.2e-06 19.1 In-house 64-133 (139) Show / Hide 
Range on Protein: 116-183
Range on HMM: 64-133/139
Sequence Identity: 25% (18 aa)

FIEIVDNFINERPF--DVIAVHCTHGFNRTGFLIVCYLVERLDCSVSAALAIFASARPPGIYKQDYINEL
... . .||.|      .. |||  |  |.  ... ||... . |.. ||    .|||.    . .|. |
ylkealdFieearskdgrvlvHCnAGvSRsasvviaylmkdeelslekalekvrearpcikPneGFikqL
Phosphatase mRNA-capping-enzyme.AA DSPc 132-171 26 8e-06 22.13 Pfam 88-133 (151) Show / Hide 
Range on Protein: 132-171
Range on HMM: 88-133/151
Sequence Identity: 26% (12 aa)

IAVHCTHGFNRTGFLIVCYLVERLDCSVSAALAIF-----ASAR-P
. |||..| .|.. |...||  .  .|.. |....      . | |
VLVHCQAGISRSACLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCP
MRNA_cap_C mRNA-capping-enzyme.AA mRNA_cap_C 500-599 36 3.2e-53 187.92 Pfam 1-138 (138) Show / Hide 
Range on Protein: 500-599
Range on HMM: 1-138/138
Sequence Identity: 36% (51 aa)

ELNSVDFRLKIITE--RGE-GLL---TKKVGFL-YV-----------GGHDAP-YGRMQ-------------RLTKETRELDNRIVECTM--NQ--FGN-
|.|.|||.||...|  .|| |.|   ....|.| |.           ||...| ...|.             ..|.......|.|||||.  ..  .|. 
EMNTVDFMLKMCFECIGGEDGMLDRFQQWRGYLDYMEMPNFQKGRWWGGYNCPFFCKMYVFNKMRIFDIEWEKWTNDEKPYNNKIVECTWLVDNKQKGRP

-WDFMRERTDKKNPNSYNTARSVVDSIKHPVTKEYLLN
 |.|||.||||.|||..||||.|..||...||||||..
EWVFMRFRTDKSNPNHINTARKVCYSIEDNVTKEYLFE
Sequence
Name Sequence Type Origin Length Description Download
mRNA-capping-enzyme.AA Protein None 649 None Fasta, JSON
mRNA-capping-enzyme.NA RNA None 1947 None Fasta, JSON
mRNA-capping-enzyme.AA.PD_52-190 Protein Phosphatase Domain None 139 None Fasta, JSON