Gene CG5830
CG5830
Species: D.melanogaster
Alias: CG5830
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of CG5830.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | CG5830.AA | Subfamily.SCP.PD | 88-250 | 79 | 6.6e-96 | 307.6 | In-house | 1-163 (163) | Show / Hide |
Range on Protein: 88-250 Range on HMM: 1-163/163 Sequence Identity: 79% (129 aa) HRKCMVIDLDETLVHSSFKPIPNADFIVPVEIDGTVHQVYVLKRPHVDEFLQKMGELYECVLFTASLAKYADPVADLLDKWNVFRARLFRESCVYYRGNY ..||.|.|||||||||||||..||||.||||||||||||||||||.|||||.|.|||.|.||||||||||||||||||||.||..|||||||||...||| ekkclvldldetlvhssfkpvenadfvvpveidgtvhqvyvlkrpfvdeflkkvgelfevvlftaslakyadpvadlldkknvikarlfrescvfhkgny IKDLNRLGRDLQKIVIVDNSPASYIFHPDNAVPVKSWFDDVTDCELRELIPLFEKLSKVDSVY .|||.||||||.|.||||||||||||||||||||.||||| .|.||..|.||.|.||||..|. vkdlsrlGrdlkkvvivdnspasyifhpdnavpveswfddeedtelldllplleelskvedvl |
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| Phosphatase | CG5830.AA | CPDc | 88-231 | 43 | 3.8e-78 | 266.83 | SMART | 1-173 (173) | Show / Hide |
Range on Protein: 88-231 Range on HMM: 1-173/173 Sequence Identity: 43% (75 aa) HRKCMVIDLDETLVHS--------------SFKPIPNADFIVP----------VEIDGTVHQVYVLKRPHVDEFLQKMGELYECVLFTASLAKYADPVAD ..|. |.|||.||||| |||. ..|||.| |||||..||.||.|||||.|||......||...||... .|||||.| KKKTLVLDLDHTLVHSCMIPTLHHWMKYLRSFKEWTRRDFIWPQLKWFHMCMIVEIDGHPHQWYVKKRPHVHEFLKRCSKWYEMHVFTMGMRMYADPVLD LLD-KW-NVFRARLFRESCVYYRGN-YIKD-LNRLGR-DLQKIVIVDNSPASYIFHPDNAVPVKSWFDDVTDC .|| |. ....||.|..|||..|. |.|| |....| || ...|.|.||.|. .||.||.|.|.||.. |. MLDPKRKYFIYRRLYRDHCVYHKGKTYVKDTLSLVNRCDLSMVIIIDDSPDSWPWHPENAIPIKPWFYFMHDT |
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| Phosphatase | CG5830.AA | NIF | 90-250 | 43 | 1.9e-75 | 261.78 | Pfam | 1-189 (189) | Show / Hide |
Range on Protein: 90-250 Range on HMM: 1-189/189 Sequence Identity: 43% (82 aa) KCMVIDLDETLVHSS--FKPIPNADFIVPVEIDGTVHQVYVLK-RPHVDEFLQKMGELYECVLFTASLAKYADPVADLLDK--WNVF--RARL---FRES |. |.||||||||.. ..| .. |||||. ..| ||.|| | ||..|||||.| ..|| |..|||. .||||| | .|. ..| . || .||. KTLVLDLDETLVHCNPWWEPPNWHDFIVPIPFNGQNHQWYVYKPRPYCDEFLQHMSKYYEIVIWTASMKEYADPVIDYIDPKSKKYFDGHHRLICWYREH CV-YYRG-NY-I-KDLNRL--GR-DLQKIVIVDNSPASYIFHPDNAVPVKS-WFD-----D-VTD--CELRELIPLF-EKLS-KV-DSVY |. |..| || . |||..| .| || ...|||||| |. ..|||..|... |.. | | || .|.|.. |.|. .. | | CWLYRNGGNYYVKKDLSILWYNRWDLSRVIIVDNSPHSW-LQPDNGIPIPPYWYGYHDDDDSPDDFWNELLDLLPFLIEYLALQCLDDVR |
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| Phosphatase | CG5830.AA | Family.FCP.PD | 89-249 | 57 | 5e-67 | 214.1 | In-house | 2-163 (164) | Show / Hide |
Range on Protein: 89-249 Range on HMM: 2-163/164 Sequence Identity: 57% (92 aa) RKCMVIDLDETLVHSSFKPIPNADFIVPVEIDGTVHQVYVLKRPHVDEFLQKMGELYECVLFTASLAKYADPVADLLDK-WNVFRARLFRESCVYYRGNY .|..|.|||||||||..|| ...||.|.||||.. ..|||.||||.||||.|..||||.|.|||| .||||||||.||. ...|..||.|..||..|||. kklLVlDLdetLvhselkpknkpdfvvkveideleetvyvkkRPhldeFLekvselyeiviftastrkyadpvadiLDpekklfkkrllrdecvlvkgny IKDLNRLGRDLQKIVIVDNSPASYIFHPDNAVPVKSWFDDVTDCELRELIPLFEKLSKVDSV |||..|||||.|..|.|.||.|| ..||||..|||...| .| || .|.|..|.|.|.. | vkdLsklgrdlskviiiDdspdsyklnpdnaikvksfkedpkDteLldLlpfleslakeedv |
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| Phosphatase | CG5830.AA | Subfamily.HSPC129.PD | 89-249 | 48 | 1.2e-54 | 173.6 | In-house | 2-163 (164) | Show / Hide |
Range on Protein: 89-249 Range on HMM: 2-163/164 Sequence Identity: 48% (78 aa) RKCMVIDLDETLVHSSFKPIPNADFIVPVEIDGTVHQVYVLKRPHVDEFLQKMGELYECVLFTASLAKYADPVADLLDKW-NVFRARLFRESCVYYRGNY . ..|.||||||||.|......| . .|| . ...|||| ||.. |||... .|.| .||||| ||| . |||| . .| ||||| || ||| efslvldldetlvhcslakledatlsfkveyqdktyqvyvrlrpflreflervsklfevilftaskkvyadklldlldpekklvrhrlfrehcvcvdgny IKDLNRLGRDLQKIVIVDNSPASYIFHPDNAVPVKSWFDDVTDCELRELIPLFEKLSKVDSV ||||. |||||.| .|||||| .. . .| .|..|||.| .| || .|.|..||| . . | ikdlsilGrdlsktiivdnspqafayqlenGipieswfadendsellkllpfleklaekedv |
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| Phosphatase | CG5830.AA | Subfamily.DULLARD.PD | 89-246 | 41 | 1.1e-50 | 160.8 | In-house | 2-168 (172) | Show / Hide |
Range on Protein: 89-246 Range on HMM: 2-168/172 Sequence Identity: 41% (68 aa) RKCMVIDLDETLVHS--------SFKPIPNADFIVPVEIDGTVHQVYVLKRPHVDEFLQKMGELYECVLFTASLAKYADPVADLLDK-WNVFRARLFRES || .|.||||||.|| . |. . ||.. | |. . ..|| ||||||.||... . |. |.||||. .||..|.| ||..... |..|..|. rktlvldldetlihsahdsvtkstvkegtapdfklkvlierepvlfyvykrPhvdlfldvvskWydlviftasmeeyaaavvdkldsgrgilkrryyrqh CVYYRGNYIKDLNRLGRDLQKIVIVDNSPASYIFHPDNAVPVKSWFDDVTDCELRELIPLFEKLSKV |.|.||| . ||....|.|||| .| .||||.|.|||. | .| .| .|.|... | . CtlesgkytkdlslvsedlssviilDnspvayrknpdnaipikswisdpsdtallnllPfldalrft |
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| Phosphatase | CG5830.AA | Group.HAD.PD | 89-244 | 37 | 6.2e-50 | 159.1 | In-house | 1-182 (190) | Show / Hide |
Range on Protein: 89-244 Range on HMM: 1-182/190 Sequence Identity: 37% (68 aa) RKCMVIDLDETLV-HSSFKPIPNADFIVPVEIDGTV----HQVYVLKR------------PHVDEFLQKMGELYECVLFTASLAKYADPVADLLDKW-NV ... |.|||..|. |.|..|. .... ..|.|. |. ...|.||| ||.||||...|||||.|.|||.. .|||||.. .|....| kdtlvlDldgvlwlhgspepleglrskgkvlifltnnatksrlyllkrlallgflveevephldeflervgelyelvvftagtreyadpvvgavdvgdea FRARLFRESCVYYRGNYIK------DLNRLGRDLQKIVIVDNSPASYIF--HPDNAVPVKSWFDDVTDCELRELIPLFEKLS ..|..|..|||..|.. . ||. |.||| |.||.||.|....| .|.||.......||. | || ||| .|... fsyrklrdacvylkgpgalllatnrdlgalvrdlekvviidnkpsvfafecnpenalmigdfiddildaellglipdlenid |
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| Phosphatase | CG5830.AA | Subfamily.TIM50.PD | 128-245 | 37 | 1e-31 | 99.1 | In-house | 26-143 (150) | Show / Hide |
Range on Protein: 128-245 Range on HMM: 26-143/150 Sequence Identity: 37% (44 aa) VLKRPHVDEFLQKMGELYECVLFTASLAKYADPVADLLDKWNVFRARLFRESCVYYRGNYIKDLNRLGRDLQKIVIVDNSPASYIFHPDNAVPVKSWFDD . ||| || ||....||.| |.||.. . .| |. | || .. . ||||... | |. .|||. | |||.|...|| ..|. ..|.||. .| | . fkkrPgvdafleelaelfeivvftseqgltaaplidkldPkqlimyrlfrdatkyvdGehvkdlsklnrdlskvivvdldkesvklqpenalalkkwkGn VTDCELRELIPLFEKLSK | || .|......... addrelldllaflktiat |
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| Phosphatase | CG5830.AA | Subfamily.FCP1.PD | 91-222 | 28 | 2.5e-16 | 49.5 | In-house | 4-141 (150) | Show / Hide |
Range on Protein: 91-222 Range on HMM: 4-141/150 Sequence Identity: 28% (38 aa) CMVIDLDETLVHSSFKPI-----PNADFIVPVEIDGTVHQVYVLKRPHVDEFLQKMGELYECVLFTASLAKYADPVADLLDK-WNVFRARLFRESCVYYR ..|.|||.||.|.. .|. . | .. . . || .||.. |||.|. .||| ..| . .||. .| .||. ..| |.. . .| vLvvDlDqtlihttkdptievkeeklkdikkftlpeekevyyvklRpnlkeFleklsklyelhiytmgtraYaeqiakilDpekklFserilsrdellna GNYIKDLNRL-GRDLQKIVIVDNSPASYIFHpDNAVPVK .|..| .. . .||.|. . . |. .| . || ssktkklkklfptgdsmvviiDDredvWnfa-enlikvk |
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