CG32487
Species: D.melanogaster
Alias: CG32487
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: HAD
Family: NagD
Subfamily: PGP
Protein domain

Protein domains of CG32487.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase CG32487.AA Subfamily.PGP.PD 31-269 43 8.9e-85 272.1 In-house 1-243 (243) Show / Hide
Range on Protein: 31-269
Range on HMM: 1-243/243
Sequence Identity: 43% (105 aa)

IDTIIFDGNGVLWSHGKVLENAAETFNALRAMGKKAFICTNNSVTSVEGICKYAQEMGFLVAK-NEILSSVQTLAKFMKEKK---FKKKCYVVGGQGIVD
.||..|| .||||.. .....|.|..|||||.|||....||||... | ..|.....|| |.| .|||||...||...|..|    ||| |..| .|. .
fdtvlfDcdGVlWlgetaipgavevlnaLraagKkvlfvtNnstktreeylkkfkklgfkvlkkeeilssaavladylkqakakkekkkvyligeeglke

ELKLVGIESLPLDHSSLQGFSMPDHIHSIYLDPNVGAVVVGSDKDFNTIKLTKACCYLRDSEVMFVATSRDAALPAAPGRMVPSAGVMVAAIQAASQRMP
||. .|||||   ...|..    | .... |...||||||| |..|. .||.||. ||.. .|.||||..|..||..|....|..|.|||...||.|.| 
eleelgieslgvgpdkledeldgdlaekvklekdvgaVvvgfdehfsyvklakAlnylqnpdvlfvatneDetlplnpevvipgtGslvaavetasgrep

FTCGKPNPYMCIDLMQKGVIQPDRTLIIGDTMCTDILLGYKCG
..|||.....  |..|  |.|.|||..||...||||.| .|| 
lvvGKPskllldallekakidpertlmvGDrldtDilfgkncG

Phosphatase CG32487.AA Family.NagD.PD 31-269 41 8.7e-75 239.6 In-house 1-239 (239) Show / Hide
Range on Protein: 31-269
Range on HMM: 1-239/239
Sequence Identity: 41% (100 aa)

IDTIIFDGNGVLWSHGKVLENAAETFNALRAMGKKAFICTNNSVTSVEGICKYAQEMGFLVAKNEILSSVQTLAKFMKEKKFK---KKCYVVGGQGIVDE
|||..|| .||||.. |....|.|..|.||..||| ...|||| .| | ..|  |..|| | ..||.||....|...|..| |   || |..| .|. .|
idtvlfDcdGVLwlgekaipgavealnrLrqkgkkvlfvTNnstksreellkklqklgfkvseeeifssaaaaadylkkrkkkpfkkkvyligeeglkee

LKLVGIESLPLDHSSLQGFSMPDHihSIYLDPNVGAVVVGSDKDFNTIKLTKACCYLRDSEVMFVATSRDAALpAAPGRMVPSAGVMVAAIQAASQRMPF
|. .|||||    ..|..    |   .. |...||||||| |..|.  ||.||. ||.. .|.|.|| .|. | ..|....| || .|||...|..| ..
leelgieslgtgpdkledeldgdl--evdlekdvgaVvvgadehfsyeklakAfryLqnpdvlfiatnedktl-kepevlipgaGsfvaaletatgreal

TCGKPNPYMCIDLMQKGVIQPDRTLIIGDTMCTDILLGYKCG
..|||.....  |..|  ..|.||..|||.. ||||.. |||
vvGKPskllfealleklgvdpertvmiGDrlntDilfaqkcG

Phosphatase CG32487.AA Group.HAD.PD 31-279 23 1.1e-22 69.2 In-house 1-187 (190) Show / Hide
Range on Protein: 31-279
Range on HMM: 1-187/190
Sequence Identity: 23% (61 aa)

IDTIIFDGNGVLWshgkvLENAAETFNALRAMGKKAFICTNNSVTSVEGICKYAQEMGFLVAKNEilssvqtlakfmkekkfkkkcyvvggQGIVDELKL
.||...|  ||||     |. ..|. ..|| .||... .|||.  |   . | .. .|||| ..|                           ..|. |  
kdtlvlDldgvlw-----lhgspepleglrskgkvlifltnnatksrlyllkrlallgflveeve--------------------------phldefler

VgieslpldhS----------SLQGFsmpdhihsiyLDPNVGAVVVGsDKDFNTIKLTKACCYLRDSEVMFVATSRdaalpaAPGRMVPSAGvMVAAIQA
       .          ..  .          .||.||||.|| |. |.  ||..||.||.. .. ..|| |       .| .|.    .|..|.  ..
v---------gelyelvvftagtrey----------adpvvgavdvg-deafsyrklrdacvylkgpgalllatnr------dlgalvrdle-kvviidn

ASQRMPFTCgkpnpymcidlmqkgviQPDRTLIIGDTMcTDILLGYKCG----FQTLLVGTGV
.  | |                 .|...|.||| . .|||   ..|    .... |..|.   
kpsvfafec-----------------npenalmigdfi-ddildaellglipdlenidvrfgk

Phosphatase CG32487.AA Subfamily.LHPP.PD 32-114 23 3.8e-11 31.0 In-house 2-84 (213) Show / Hide
Range on Protein: 32-114
Range on HMM: 2-84/213
Sequence Identity: 23% (19 aa)

DTIIFDGNGVLWSHGKVLENAAETFNALRAMGKKAFICTNNSVTSVEGICKYAQEMGFLVAKNEILSSVQTLAKFMKEKKFKK
.... |  |||. . ... ...|  . |.. | |  ..||.. .| . . .  |..|| | ..|...|. . ....|..| . 
kgvllDlsGvlyveeaaipgsveAlkrLkqsglkvrfvtnttkeskrelverLqrlgfkveeeevftslpaarqllkkeklrp

Phosphatase CG32487.AA Subfamily.LHPP.PD 162-269 23 5.7e-08 20.7 In-house 105-213 (213) Show / Hide
Range on Protein: 162-269
Range on HMM: 105-213/213
Sequence Identity: 23% (25 aa)

GAVVVGS-DKDFNTIKLTKACCYLRDSEVMFVATSRDAALPAAPGRMVPSAGVMVAAIQAASQRMPFTCGKPNPYMCIDLMQKGVIQPDRTLIIGDTMCT
|||.|  .. ||  .|.||   |.. .   . .   .   .    ..  .|  |.|.. | .      |||...   . .|.  ..|.....||| .  |
navviglapesfnyetlnkafrlllekkkkvLiaigkgkyykrkdglaldvGafvkaLeyatdveaevvGkPsklfFesalqelgvdpeeavmiGDDvkd

DILLGYKCG
.    |.| 
DvgGAqkvG

Sequence
Name Sequence Type Origin Length Description Download
CG32487.AA Protein None 320 None Fasta, JSON
CG32487.NA RNA None 960 None Fasta, JSON
CG32487.AA.PD2_190-269 Protein Phosphatase Domain None 80 None Fasta, JSON
CG32487.AA.PD1_40-120 Protein Phosphatase Domain None 81 None Fasta, JSON