CG11291
Species: D.melanogaster
Alias: CG11291
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: HAD
Family: NagD
Subfamily: PGP
Protein domain

Protein domains of CG11291.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase CG11291.AA Subfamily.PGP.PD 24-260 38 1.2e-66 212.8 In-house 1-243 (243) Show / Hide
Range on Protein: 24-260
Range on HMM: 1-243/243
Sequence Identity: 38% (93 aa)

IDTIICSTDGVLWQENTPIEGSVEAFNAIISKGKRCLIATNECCLTNKDLFQKAKCLGFNVKE-QDIFSSSGAIASYLSDRKF---KKKILVLGGDGIRK
.||...  |||||...|.|.|.||..||. ..||..|. ||    | .....|.| |||.|.. ..|.||  ..|.|| ..|.   |||. ..| .|...
fdtvlfDcdGVlWlgetaipgavevlnaLraagKkvlfvtNnstktreeylkkfkklgfkvlkkeeilssaavladylkqakakkekkkvyligeeglke

DLKEAGFCSVVNDLQPNDQ-KKIDFVRSLVLDPDVGAVLVARDDNMIANELLVACNYLQNPKVLFLTTCIDGFQP-FGKKRIPDAGSLASAIEIIVQRKP
.|.|.|. |.    .  ..  . |.  .. |..|||||.|. | ..   .|. |.||||||.|||. |  |   |   ...||..|||..|.|....|.|
eleelgieslgvgpdkledeldgdlaekvklekdvgaVvvgfdehfsyvklakAlnylqnpdvlfvatneDetlplnpevvipgtGslvaavetasgrep

IVLGKPNQRILGKLMKSGEIKPEKTLVIGNSLKSDILFASICG
.|.|||.. .| .|... .|.||.||..|..|..||||.. ||
lvvGKPskllldallekakidpertlmvGDrldtDilfgkncG

Phosphatase CG11291.AA Family.NagD.PD 24-260 38 1.5e-63 202.8 In-house 1-239 (239) Show / Hide
Range on Protein: 24-260
Range on HMM: 1-239/239
Sequence Identity: 38% (92 aa)

IDTIICSTDGVLWQENTPIEGSVEAFNAIISKGKRCLIATNECCLTNKDLFQKAKCLGFNVKEQDIFSSSGAIASYLSDRKFK---KKILVLGGDGIRKD
|||...  |||||.....|.|.|||.|.. .|||..|. ||.   ....|..| . |||.|.|..||||  |.|.|| .|| |   ||. ..| .|....
idtvlfDcdGVLwlgekaipgavealnrLrqkgkkvlfvTNnstksreellkklqklgfkvseeeifssaaaaadylkkrkkkpfkkkvyligeeglkee

LKEAGFCSVVNDLQPNDQKKIDFVrSLVLDPDVGAVLVARDDNMIANELLVACNYLQNPKVLFLTTCIDGFQPFGKKRIPDAGSLASAIEIIVQRKPIVL
|.|.|. |.    .  ...  . . .. |..|||||.|  |...  ..|  |..|||||.|||..|  | . .  .. ||.|||...|.|....|...|.
leelgieslgtgpdkledeldgdl-evdlekdvgaVvvgadehfsyeklakAfryLqnpdvlfiatnedktlkepevlipgaGsfvaaletatgrealvv

GKPNQRILGKLMKSGEIKPEKTLVIGNSLKSDILFASICG
|||.. .. .|... ...||.|..||..|..|||||. ||
GKPskllfealleklgvdpertvmiGDrlntDilfaqkcG

Phosphatase CG11291.AA Subfamily.LHPP.PD 27-112 30 1.5e-14 42.1 In-house 4-89 (213) Show / Hide
Range on Protein: 27-112
Range on HMM: 4-89/213
Sequence Identity: 30% (26 aa)

IICSTDGVLWQENTPIEGSVEAFNAIISKGKRCLIATNECCLTNKDLFQKAKCLGFNVKEQDIFSSSGAIASYLSDRKFKKKILVL
..    |||..|...| ||||| . . ..| .  . ||.   ....| .. . |||.|.|...|.|  |....| ..| .  .|| 
vllDlsGvlyveeaaipgsveAlkrLkqsglkvrfvtnttkeskrelverLqrlgfkveeeevftslpaarqllkkeklrpfllve

Phosphatase CG11291.AA Group.HAD.PD 25-261 23 7.7e-14 40.4 In-house 2-178 (190) Show / Hide
Range on Protein: 25-261
Range on HMM: 2-178/190
Sequence Identity: 23% (58 aa)

DTIICSTDGVLWqentpIEGSVEAFNAIISKGKRCLIATNECCLTNKDLFQKAKCLGFNVKEQDifsssgaiasylsdrkfkkkilvlggDGIRKDLKEA
||..   |||||     ..|| |. ..  ||||. .  ||.   ..  | .....|||.|.|.                           ..... |. .
dtlvlDldgvlw-----lhgspepleglrskgkvlifltnnatksrlyllkrlallgflveeve--------------------------phldeflerv

gfcsvvnDLQpNDQKKIDFVRSLVLDPDVGAVLVArDDNMIANELLVACNYLQNPKVLFLTTCIdgfqpfgkkripDAGSLASAIE--IIVQRKPIVLGK
       .   .. .  ...   ..||.|||| |. |    .. |  ||.||..|..|.|.|.             | | | .. |  .|.. || | . 
-------gel-yelvvftagtreyadpvvgavdvg-deafsyrklrdacvylkgpgalllatnr------------dlgalvrdlekvviidnkpsvfaf

PNqrilgklmksgeiKPEKTLVIGNSLkSDILFASICG----F
               .||..|.||. . .||| |  .|    .
ec-------------npenalmigdfi-ddildaellglipdl

Phosphatase CG11291.AA Subfamily.LHPP.PD 201-260 26 5.6e-08 20.7 In-house 154-213 (213) Show / Hide
Range on Protein: 201-260
Range on HMM: 154-213/213
Sequence Identity: 26% (16 aa)

DAGSLASAIEIIVQRKPIVLGKPNQRILGKLMKSGEIKPEKTLVIGNSLKSDILFASICG
|.|. ..|.|  .. .  |.|||..    . ... ...||....||. .|.|.  |  .|
dvGafvkaLeyatdveaevvGkPsklfFesalqelgvdpeeavmiGDDvkdDvgGAqkvG

Sequence
Name Sequence Type Origin Length Description Download
CG11291.AA Protein None 308 None Fasta, JSON
CG11291.NA RNA None 924 None Fasta, JSON
CG11291.AA.PD1_33-64 Protein Phosphatase Domain None 32 None Fasta, JSON
CG11291.AA.PD2_196-260 Protein Phosphatase Domain None 65 None Fasta, JSON