• Phosphatome.Net

Gene CG14216

CG14216
Species: D.melanogaster
Alias: CG14216
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: LMWPTP_SSU72
Family: Ssu72
Subfamily: Ssu72
Protein domain

Protein domains of CG14216.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase CG14216.AA Ssu72 5-195 49 1e-127 435.41 Pfam 1-214 (214) Show / Hide 
Range on Protein: 5-195
Range on HMM: 1-214/214
Sequence Identity: 49% (106 aa)

SKLAVAVVCSSNMNRSMEAHNFLAKKGFNVRSYGTGERVKLPGMAFDKPNVYEFGTKYEDIYRDLESKDKEF--YTQNGLLHMLDRNRRIKKCPERFQD-
|||....||.||.|||||||..|.|.|..|||||||..|.|||...||||||.||| |.|||.||||.|...  |||||||||||||||||.||||.|| 
SKLKFCTVCASNQNRSMEAHKVLKKAGYDVRSYGTGSHVRLPGPSIDKPNVYDFGTPYDDIYNDLESQDEDLVNYTQNGLLHMLDRNRRIKWCPERWQDW

-TKEQ--FDIIVTVEERVYDLVVMHMESMESVDNRPVHVLNVDVVDNAEDALMGAFVITDMINMMA----------------KSTDLDNDIDELIQEFEE
  .|.  ||...| |||..|.|.........  |.|||| |||. || |.|..||. | |...|..                .|.|....|.|...|..|
FCTERGKFDVVITCEERCFDAVCEDLMNRGQQLNQPVHVINVDIKDNHEEAIIGAKAICDLCQMLHDFAQKERQGWHQFCDEASEDWEDQIMEILHEWQE

RR-KRVILHSVLFY
.  .| .|..| ||
QHPHRPFLYCVCFY
Phosphatase CG14216.AA Family.Ssu72.PD 6-195 67 8.1e-100 319.9 In-house 2-191 (191) Show / Hide 
Range on Protein: 6-195
Range on HMM: 2-191/191
Sequence Identity: 67% (128 aa)

KLAVAVVCSSNMNRSMEAHNFLAKKGFNVRSYGTGERVKLPGMAFDKPNVYEFGTKYEDIYRDLESKDKEFYTQNGLLHMLDRNRRIKKCPERFQDTKEQ
|| .|||||||.|||.|||..|.||||||.|||||..|||||...||||||||||.|||||.||..||||.|||||||.||||||||||.|||||..|..
klriavvcssnqnrsleahkllkkkGfnvksyGtgsavklPGpsidkPnvyefgttyediykdlkekdkelytqnGllemldrnrrikkaPerfqeekkk

FDIIVTVEERVYDLVVMHMESMESVDNRPVHVLNVDVVDNAEDALMGAFVITDMINMMAKSTDLDNDIDELIQEFEERRKRVILHSVLFY
|||..|||||||| ||...||.|. ...||||.|||. ||||.| .|||.|.....|..||.||...|||...||||..|| .||||.||
fdivltveervydavvedlesreeksskpvhvinvdikdnaeeatlGaflilelaemleksedledeideileefeektkrellhsvafy
Phosphatase CG14216.AA Subfamily.Ssu72.PD 6-195 67 8.1e-100 319.9 In-house 2-191 (191) Show / Hide 
Range on Protein: 6-195
Range on HMM: 2-191/191
Sequence Identity: 67% (128 aa)

KLAVAVVCSSNMNRSMEAHNFLAKKGFNVRSYGTGERVKLPGMAFDKPNVYEFGTKYEDIYRDLESKDKEFYTQNGLLHMLDRNRRIKKCPERFQDTKEQ
|| .|||||||.|||.|||..|.||||||.|||||..|||||...||||||||||.|||||.||..||||.|||||||.||||||||||.|||||..|..
klriavvcssnqnrsleahkllkkkGfnvksyGtgsavklPGpsidkPnvyefgttyediykdlkekdkelytqnGllemldrnrrikkaPerfqeekkk

FDIIVTVEERVYDLVVMHMESMESVDNRPVHVLNVDVVDNAEDALMGAFVITDMINMMAKSTDLDNDIDELIQEFEERRKRVILHSVLFY
|||..|||||||| ||...||.|. ...||||.|||. ||||.| .|||.|.....|..||.||...|||...||||..||.||||.|| 
fdivltveervydavvedlesreeksskpvhvinvdikdnaeeatlGaflilelaemleksedledeideileefeektkrellhsvafy
Phosphatase CG14216.AA Group.LMWPTP_SSU72.PD 8-195 41 9.1e-56 176.3 In-house 2-161 (163) Show / Hide 
Range on Protein: 8-195
Range on HMM: 2-161/163
Sequence Identity: 41% (78 aa)

AVAVVCSSNMNRSMEAHNFLAKkgfnvrsygtgeRVKLPGMAFDKpNVYEFG-TKYEDIYRDLESKDKEFYTQNGLLHMLDrnrrikKCPERFQDTK-EQ
|..||..|..||.||...| |             |||||.. || ||..|| |.|||.|..|...|||.|.|||||.|||      ..|..||... |.|
kvlfVClgNicRSpeAeavlkk------------lvklpglssdk-nvdsfgtttYedgysplkradkelykqnGllrmld------hrprqfqeedfek

FDIIVTVEERVYDLVVMHMESMESVDNrpvhvlnvdvvDNAEDALMGAFVITDMINMMAKSTDLDNDIDELIQEFEERRKRVILHSVLFY
|.|.|..||..| |....||.|. .|           |||| ||.||| |... ... ...||....|| ..||||. |...||.. || 
FDyiltmdernldevkedlesrekksn-----------dnaeeallGafqisklaeiiedpedleeyydeeleeFeesykqlvlhckaFy
Sequence
Name Sequence Type Origin Length Description Download
CG14216.AA Protein None 195 None Fasta, JSON
CG14216.NA RNA None 585 None Fasta, JSON
CG14216.AA.PD_5-195 Protein Phosphatase Domain None 191 None Fasta, JSON