Gene alph
alph
Species: D.melanogaster
Alias: alph
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of alph.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | alph.AA | Family.PPM.PD | 11-357 | 35 | 5.6e-106 | 345.0 | In-house | 4-359 (495) | Show / Hide |
Range on Protein: 11-357 Range on HMM: 4-359/495 Sequence Identity: 35% (130 aa) AKHNDEGEGNKLLFGVSSMQGWRSEMEDAYYARAGLGDALpDWSFFAVFDGHAGCKVSEHCAKHLLESIISTEEFIG------------GDHVKGIRTGF |... ....|.| .||.||||||||||||. . .|.. |.|.|.|||||.| ...|..||.| . ... .|. . . . .|..| aarteasssnglrygvasmqgwrsemeDahvvvenlenne-dfslfgvfDGhgGaeaaefaakklhkilkkqlekkddeksstsaessaekvkealrkaf LRIDEVMRELPEFTReSEKCGGTTAVCAFVGLTQVYIANCGDSRAVLCRQGVPVFATQDHKPILPEEKERIYNAGGSVMI--KRVNGTLAVSRALGDYDF |..|| ..| . .. ..| .|||||.... ...|.||.|||||||||.| .| ..|||| |||.||| .|||.|.| .||||.|||||||||.|. leldeelseelneks-agkdsGtTAvvvlirgkklyvAnaGDsravLcrngkavelskdHkpenpeEreRIekagGkvvirdgrvnGvlavsRalGdfdl KNvkekgqCEQL-VSPEPEI-FCQSRQDSDEFLVLACDGIWDVMSNEDVCSFIHSRM-RVTSNLVSIANQVVDTCLHKGSRDNMSIIIIAFPGAPKPTEE |. ||. ||.||.| .. .|..|||||||.||.|||.|||.|........ . ...| .||...||..|.||||||......|.....| ... kk------eeqaivsaePditsvkltqeedeflvlasdGlWdvlsneevvelvretleekeedleeiaeeLvdealakgsrDNiTvlvvalyenikqqnr AIEAEHRLEKQIEKITRDEIESSKITDYVDLLKCLQNRDDIEGLPPGGGLQSKYHVIERTFKQE .......|.......... ..... . .. .. .. .||. . ..|... . ........ fvlnknslmtrrstfedttlrrlqeeispptgnlamvftdiksstflwelfpnamrtaikthnd |
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| Phosphatase | alph.AA | Subfamily.PPM1A.PD | 13-314 | 59 | 2.2e-143 | 467.2 | In-house | 1-308 (309) | Show / Hide |
Range on Protein: 13-314 Range on HMM: 1-308/309 Sequence Identity: 59% (183 aa) HNDEGEGNKLLFGVSSMQGWRSEMEDAYYARAGLGDALPDWSFFAVFDGHAGCKVSEHCAKHLLESIISTEEFIGG-------DHVKGIRTGFLRIDEVM .|.|||||.| .|.||||||| |||||..| ..| ..|.|||||||||||||.|||..|||||||.|...||| .. .. ...|.|||..|| . eneegegnglryglssmqgwRvemEDahtavidlpsklkdwsffavfDGHaGskvskycakhlleaileeeefkaskeksskekvkealrkgfLelDeki RELPEFTRESEKCgGTTAVCAFVGLTQVYIANCGDSRAVLCRQGVPVFATQDHKPILPEEKERIYNAGGSVMIKRVNGTLAVSRALGDYDFKNVKEKGQC |.|.|......|. |.|||...| ...|.||||||||||.|.| ||||.||||. |.||||| |||||||||||||.|||||||||||.|. .||... rklvelskgedks-GsTavvvlvspkklylancGDsRavlsrngkvvfateDHkpsdpkEkeRienAgGsvmikRvnGsLAvsRalGDydykekpekkat EQLVSPEPEIFCQSRQDSDEFLVLACDGIWDVMSNEDVCSFIHSRMRVTSNLVSIANQVVDTCLHKGSRDNMSIIIIAFPGAPKPTEEAIEAEHRLEKQI |||||||||.....|...||||||||||||||||||.|..|..||..||..| ..||...||||.||||||||.|....|||||..||||..|..|.|.. eqlvspepevtvierdeedeflvlacDGiwDvmsneevaefvksrlevtddleevanelldtcLekgsrDNmsvilvllpgapkvseeaikkekeldkel EKITRDEIE |.......| eekveevle |
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| Phosphatase | alph.AA | Group.PPM.PD | 12-358 | 36 | 1.4e-111 | 363.4 | In-house | 28-395 (459) | Show / Hide |
Range on Protein: 12-358 Range on HMM: 28-395/459 Sequence Identity: 36% (135 aa) KHNDEGEGNKLLFGVSSMQGWRSEMEDAYYARAGLGDALpdwSFFAVFDGHAGCKVSEHCAKHLLESIISTEEFIG------------------GDHVKG .. .|.||.| .||.||||||.||||.. . ... |||.|||||.| ...|..||.| . . . .. .| .|. lessagsgnglrygvasmqgwrkemEDrhvivenfdnnd---sffgVfDGHgGaeaaefaakkLpkilkkqlkkkkdevskksaeasldnddrgekvkka IRTGFLRIDEVMRELPEFTRESEKCGGTTAVCAFVGLTQVYIANCGDSRAVLCRQGVPVFATQDHKPILPEEKERIYNAGGSVMI-KRVNGTLAVSRALG .||..|| ..| . ..|..| .|||||.|.. ..|.||.|||||||||.| .| ..|||| |||.||| .|||||.| .||||.|||||||||.| lrsafleldedlseeanekeepgkdsGtTAvvalingkklyvANaGDSravLcrngkavplskdHkpenpeEreRIekagGsveidgRvnGilavsRalG DYDFKNvkekgqCEQLVSPEPEIFCQSRQDSDEFLVLACDGIWDVMSNEDVCSFIHSRMRV-----TSNLVSIANQVVDTCLHKGSR------DNMSIII .|. ||.||.||.. .. |||||||.||.|||.|||.|..|..... ...| .||...||..|.|||.||...|.. ...|.. dhdlkk------eeqmvsaePdvsvvklteedeflvlAsDGlWdvlsneevvefvretlekkkkelkkdleeiaerlvdealakgstgdgtscDNiTviv IAFPGAPKPTEEAIEAEHRLEKQIEKITRDEIESSKITDYVDLLKCLQNRDDIEGLPPGGGLQSKYHVIERTFKQEF ..|....|..||...........|.|. |..... ..|.. ...| ...... ... ........|. vtlndamrrqleivkkeevleeelafmvaelteksgltallsvqlklldaqaeeeitsvqdglqvtdrngeiiyqgl |
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| Phosphatase | alph.AA | PP2Cc | 13-282 | 28 | 3.7e-95 | 323.35 | SMART | 1-338 (338) | Show / Hide |
Range on Protein: 13-282
Range on HMM: 1-338/338
Sequence Identity: 28% (104 aa)
HNDEGEGNKLLFGV--SSMQGWRSEMEDAYYARAGLGDALPDWSFFAVFDGHAGCKVSEHCAKHLLESIISTEEFIGGDH--------------------
|. | .... .|. |||||||..||||...| ||.|||||.| .... |.|||.| ... ..| .|.
HS-MGYNSGWRYGYMESSMQGWRHPMEDAHVCRP----------FFGVFDGHGGHECAQYCRKHLHEHLAEELQFHKDDDYKENDEMQDEPEMWWRMWHD
------VKGIRTGFLRIDEVMRELPEFTRESEKCGGTTAVCAFVGLTQVYIANCGDSRAVLCRQGV----------PVFATQDHKPILPEEKERIYNAGG
. .| .|||.|| . .|||.|.. ..|.||.|||||||||.| ... |.|||| ..|..|| .|||
KWFEDWEDALRKAFLRMDEEI---------------CTAVVALIRGNKLYVANVGDSRAVLCRNGNDNWWGIRHYTAHQLTEDHKPDNEDERRRIEQAGG
--------SVMIK-----RVNGT---LAVSRALGDYDFKNVK----------------EKGQCEQLVSPEPEIFCQSR------QDSDEFLVLACDGIWD
|| ||||. ||||||.||...|. | .... |..|..||... . ..|.||.|.|||.||
RVMPMHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKW-KEDEKIEWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQMTVPTPDDDFLILCCDGLWD
VMSNEDVCSFIHSRM-----------------------RVTSNLVSIANQVVDTCLHKGSRDNMSIIII
||||..|....... ...... ..|. ..| .. .|||..|..
VMSNQEVVDIVRKCLRKWHHKPVKNQAQENAHMMRHRQKKHNDPMEAAKRLCDCAI----CDNMTVIVV
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| Phosphatase | alph.AA | PP2C | 22-277 | 37 | 1.4e-90 | 311.99 | Pfam | 1-284 (284) | Show / Hide |
Range on Protein: 22-277 Range on HMM: 1-284/284 Sequence Identity: 37% (106 aa) LLFGVSSMQGWRSEMEDAYYARAGLG---DALPDWSFFAVFDGHAGCKVSEHCAKHLL----ESIISTEEFIGG---DHVKGIRTGFLR--IDEVMRE-- . .|...||||| .||||. . . .. .. ..|.||||||||.| .... |.||| ... . ..| .| | ...| .||. .|.... WDYGFCRMQGWRHFMEDAHHCYPNMNCSSSGKDSWHFFAVFDGHGGHQAAKYCRKHLHKAMNTILKERKSFPEGNPKDVEQALRKSFLECDTDMMFYSAP -LPEF-TRESEKCGGTTAVCAFVGLTQ--VYIANCGDSRAVLCRQGVPV----FATQDHKPILPEEKERIYNAGGSVM---IKRVNGT-LAVSRALGDYD .. .. .|.|||||.. .. |.||||||||||||.| .. . |.|||| ..|..|| .|||.|| ||||. ||||||.||.. WHEQNVMHWECWHSGCTAVCAYIRNQKNILYVANCGDSRAVLCRNGNAHNWVHQLTYDHKPSNEDERRRIRQAGGWVMWWGFWRVNGVWLAVSRAFGDFH FKNVKEKGQCEQLVSPEPEIF-CQSRQDS-DEFLVLACDGIWDVMSNEDVCSFIHSRMRVTSNLVSIANQVVDTCLHKGSRDNM .|. . .. ||.|..||.| . .... ||||.|||||.|||||...||....... . . .....||.|. .||.||. YKPNHTCFPKEQPVTAEPDITPEHKITPDHDEFLILACDGLWDVMSDQEVCDIVRQCRSDWNDPMEACEKLVDYCIAYGSEDNI |
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| Phosphatase | alph.AA | Subfamily.PPM1G2.PD | 17-282 | 39 | 1.6e-80 | 260.3 | In-house | 5-275 (275) | Show / Hide |
Range on Protein: 17-282 Range on HMM: 5-275/275 Sequence Identity: 39% (107 aa) GEGNKLLFGVSSMQGWRSEMEDAYYARAGLGD--ALPDWSFFAVFDGHAGCKVSEHCAKHLLESIISTEEFIGGDHVKGIRTGFLRIDEVMRELPEFTRe |. ... .|||||||.| .||||. . | . .. ..||||||| | ||.....|.| . | . ..| | . .. .||..||... .. ganariavgvssmqGyrlnmeDahilenelleksddkslalfavfDGhGGakvakyagkklikkiakkksfkegaleqilkdafletDeellkdeklkd- sEKCgGTTAVCAFVGLTQVYIANCGDSRAVLCRQGVPVFATQDHKPILPEEKERIYNAGGSVMIKRVNGTLAVSRALGDYDFKNVKEKGQCEQLVSPEPE |.. |.||| . . ...|.||.|||||||. .| . |||| .||.|| .||| | ..||||.||.||||||.||. ..|. ||.| .|.. -esa-GstavvvlikeeklyvanaGDsravlsskgnvkalsfDhkPqeesekkriiaagGfvelnrvngnLalsralgDfefkknvkkkpeeqivtavPD IFCQSRQDSDEFLVLACDGIWDVMSNEDVCSFIHSRMRVTSNLVSIANQVVDTCLHKGSR------DNMSIIII .......||||||||||||||..|..|. ....|.. .| .|.....|.|| . |. |||...|. vlvkkldeddeflvLaCDGiWDvltnkevvdlvrerlvsgakldeiieelldkclapdssntgvGcDnmtvviv |
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| Phosphatase | alph.AA | Subfamily.PPM1E.PD | 25-282 | 34 | 7.7e-57 | 182.7 | In-house | 14-267 (269) | Show / Hide |
Range on Protein: 25-282 Range on HMM: 14-267/269 Sequence Identity: 34% (87 aa) GVSSMQGWRSEMEDAYYARAGLGDALP-----DWSFFAVFDGHAGCKVSEHCAKHLLESIISTEEFIGgDHVKGIRTGFLRIDEVMRElpEFTRESEKCg . .... | ||| . | |. . . .||||||||.| . ... |.|| | ... |... | .. .. .| ..|| . ..||. |. |.||| siaavknkrrkmEDrhvaledlnelfelkdekeraffavfDGHgGveaakyaaahlhellvrqeklke-dpaealkeafkltDerflq--kaereklks- GTTAVCAFVGLTQVYIANCGDSRAVLCRQGVPVFATQDHKPILPEEKERIYNAGGSVMI---KRVNGTLAVSRALGDYDFKnvkekgqceQLVSPEPEIF .... |.|.| |||.|.|.|.| | .. ||| ..||.|| .||| |. ||||.|.||||.||.. |. || |... . ..|...|.|| GstavvvliekdqlyvaWlGDsqallvrkgeavqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRaiGDvklk---------pyvsgeadva CQSRQDSDEFLVLACDGIWDVMSNEDVCSFIHSRMRVTS-NLVSIANQVVDTCLHKGSRDNMSIIII |||.|||. .|.|.. ... .. .. .| ..|...|.. ..||.||...... eveldgsedylilacDGlwDvvneeevvklveefladgaedlsevakllveaakeagssDnitvvvv |
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| Phosphatase | alph.AA | Subfamily.LRR-PP2C.PD | 16-283 | 34 | 1e-51 | 165.9 | In-house | 4-256 (257) | Show / Hide |
Range on Protein: 16-283 Range on HMM: 4-256/257 Sequence Identity: 34% (92 aa) EGEGNKLLFGVSSMQGWRSEMEDAYYARAGLGDAlPDWSFFAVFDGHAGCKVSEHCAKHLLESIISTEEFIGGDHVKGIRTGFLRIDEVMRELPeftres |...... | | | | |. ||| . . | .| ..|.||||.| . .......| . . . . .| .. . |.. | | | esdssrfkvgfsdmiGrrptmedelviyGsfrdk-sdedyyalfdGhgGraaakfaseelykilaelldlnnanPlkslkkaykeistqiserp------ eKCGGTTAVCAFVGLTQVYIANCGDSRAVLC-RQGVPVFATQDHKPILPEEKERIYNAGGSVMIK----RVNGTLAVSRALGDYdFknvkekgqCEQLVS ||||. ... .||||| ||||.||| ..|. . . |||| ..|..|| ..|| |. . |||||||||||||| | | | |. -kfiGttaasvliiedkvyianvGdsrvvlcqkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGds-f--------lePfvv PEPEIF-CQSRQDSDEFLVLACDGIWDVMSNEDVCSFIHSrmrvTSNLVSIANQVVDTCLHKGSRDNMSIIIIA |.. . .|.||.||||||||..|.|. .. . . |. |... | ..||||.|.|.| pdPdlsqsleiskkdkflilacdGiwdlisdeeaveivag----isdpekaaeklrdlayssGstdnisvivik |
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| Phosphatase | alph.AA | Subfamily.PPM1G.PD | 119-284 | 41 | 1.9e-51 | 165.9 | In-house | 307-482 (482) | Show / Hide |
Range on Protein: 119-284 Range on HMM: 307-482/482 Sequence Identity: 41% (73 aa) GGTTAVCAFVGLTQVYIANCGDSRAVLCRQGVPVFATQDHKPILPEEKERIYNAGGSVM-IKRVNGTLAVSRALGDYDFKNVKEKGQCEQLVSPEPEIFC ||||| | | ....|| ||||.||.|.| . ||||. ..|.||| .||| | |||| | .||||||. .|. .| . ||..| |.| . sGttavvaLvkgkklivanaGDsRcvlsrnGkaldlsiDhkPeDeveleRiekaGGkvtldgRvnGGLnlsRalGDhaYktneeLpaeeqmisalPDikk QSRQDSDEFLVLACDGIWDVMSNEDVCSFIHSRMRVT---SNLVSIANQVVDTCLHKGS------RDNMSIIIIAF .. ||||||||||||.||| ..| |...... . ..| .| ....|.|| . |||...|. . lilteedeFlvlacDGiWnvmssqevvdFvraklkeseeskklseiceeLlDaCLapdtsgDGtGCDnmtvvivql |
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| Phosphatase | alph.AA | Subfamily.ILKAP.PD | 25-281 | 29 | 1.3e-45 | 146.0 | In-house | 12-297 (298) | Show / Hide |
Range on Protein: 25-281
Range on HMM: 12-297/298
Sequence Identity: 29% (86 aa)
GVSSMQGWRSEMEDAYYARAGLGDA-------LPDWSFFAVFDGHAGCKVSEHCAKHLLESII---STEEFIG--GDHVKGIRTGFLRIDEVMRELPEFT
.... .| | ||||| | .. . |..|||||||| . ||..|..| . |. . |.. . | .. | . ||. .| . ..
afaerkGereemeDahvilndldeqtrkekskvsrvsyyavfDGhaGsrasefaaeklhkviveklpkedvsakdkeikkclvdafkktDeeflklaska
RESEKCGgTTAVCAFVGLTQVYIANCGDSRAVLCRQG-----------VPVFATQDHKPILPEEKERIYNAGGSVMIKRVNGTLAVSRALGDYDFKNVKe
. | | .|||...| .|.|| |||.|||.|. ..| ..||.| ||..|| .|||.|. ||.||.|||..|| ||..
kPvWkdG-stavvvlvvdnvlyvanlGDskavlaRakeegdkagestiasvlLskdHtpasyeerkriqkaGgvvrdgRvlGvlevsRsiGDgrfkelg-
kgqceqlVSPEPEIFCQSRQDSDEFLVLACDGIWDVMSNEDVCSFIHSRMRVT------------SN---LVSIANQVVDTCLHKGSRDNMSIII
|. .|.. .. | |.||||||.|.|.....| .|| . . .. ...... ...|| ||.....
-------vistPdvkkceLtenDlfvvlaCDGLwkvfeadevvkfilkvlededdrkikqeegksaeevrfevacerlAseavkrgssDnvtvll
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| Phosphatase | alph.AA | PP2C_C | 278-356 | 45 | 4.1e-44 | 147.81 | Pfam | 1-82 (82) | Show / Hide |
Range on Protein: 278-356 Range on HMM: 1-82/82 Sequence Identity: 45% (38 aa) SIIIIAFPGAPKPTEEAIEAEHRLEKQIEKITRDEIES----SKITDYVDLLKCLQNRDDIEGLPPGGGLQSKYHVIERTFKQ |||||.||||||..|||...|..|.|..|......||. ...|.....|||.. | |..|||||||.||...||....| SIIIICFPGAPKVSEEAVKKEAELDKYLEQRVEEIIEKMHSEHEYPDLLHVMKCLASED-IPNLPPGGGLHSKRSCIEAVYNQ |
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| Phosphatase | alph.AA | Subfamily.PPM1L.PD | 25-284 | 34 | 1.3e-43 | 139.5 | In-house | 15-273 (273) | Show / Hide |
Range on Protein: 25-284 Range on HMM: 15-273/273 Sequence Identity: 34% (92 aa) GVSSMQGWRSEMEDAYYARAGLGDALpDWSFFAVFDGHAGCKVSEHCAKHLLESIISTEEFIGGDH--VKGIRTGFLRIDEVM---RELPEFTRESEKCG | |..| | .||| . .. . . ||||||||| | .|.. . | ..| . . |. . | . | ||.. ..| |.. .|. || avysvlGrrprmedrfeieediknkt-gesffavfdGhGGefaaefakdvlvkaiknklieldadkentvpinfsklltdeilsvdekllekakraedia GTTAVCAFVGLTQVYIANCGDSRAVLC-RQGVPVFATQDHKPILPEEKERIYNAGGSVMIK---RVNGTLAVSRALGDYDFKNvkekgqcEQLVSPEPEI ||. |.| ... .|| |||| ||. ..| . . |||| ..|. || .||| . .. ||.| ||.||||||| .|. ..|| ..|.|.. GttalialvqesdlivanvGdsrGvlydkrGkaiplsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdyplkd-------knlviadpdi FCQSRQD-SDEFLVLACDGIWDVMSNEDVCSFIHSRMRVTSnlvSIANQVVDTCLHKGSRDNMSIIIIAF .| |||.||.||.|| .|||. . ||. |. | .| . ..|| ||...... . ltfdlddhkpeflilasdGlwdtfsneeavrfikerlkepd---fGakslvlesfkrGsvdnitvlvvkl |
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| Phosphatase | alph.AA | Subfamily.PPM1K.PD | 25-283 | 33 | 2.7e-41 | 131.7 | In-house | 13-263 (264) | Show / Hide |
Range on Protein: 25-283 Range on HMM: 13-263/264 Sequence Identity: 33% (86 aa) GVSSMQGWRSEMEDayyaRAGLGDALPDWSFFAVFDGHAGCKVSEHCAKHLLESIISTEeFIGGDHVKGIRTGFLRIDEVMRELPEFT---RESEKCGGT |. |..| |.| || | | . || .|||||||.| ... ..| | . | . . |. .|. .. ||..| .. | |..| GkdsliGkraened----rfklkeldpdllyfavfdGhgGssaadfvhdkleeivrrll-ekekdleevlkqafeeldkklkrylefsvaeaellssGtt TAVCAFVGLTQVYIANCGDSRAVLCRQGVPVFATQDHKPILPEEKERIYNAGGSVMI-----KRVNGTLAVSRALGDYDFKNvkeKGqceQLVSPEPEIF . . ... .|. |||||.|||.| . |.||.| |||||| .||||| .||. ||..|.||| |.|.| . || . . . .. atvsllrdGnelvlaslGdsrailcrnGkakkltkdhdPerkeekerikaagGsvewnslgkplvnsrlamtrslGdldlkr---yG---viatPetksl cQSRQDSDEFLVLACDGIWDVMSNEDVCSFIhsrmRVTSNLVSIANQVVDTCLHKGSRDNMSIIIIA | |||| ||| .|......| .. |. . |. |... | || || ..... -kvkhaadsflvlitdgisfvvnsqelcdlv----rlchdpeeaahavteqalqygsednatavvvp |
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| Phosphatase | alph.AA | Subfamily.PPM1D.PD | 21-179 | 30 | 2.3e-28 | 89.4 | In-house | 7-180 (311) | Show / Hide |
Range on Protein: 21-179 Range on HMM: 7-180/311 Sequence Identity: 30% (53 aa) KLLFGVSSMQGWRSEMEDAYYARAGLGDA--LPDWSFFAVFDGHAGCKVSEHCAKHLLESIISTEEFIGGDH---VKGIRTGFLRIDEVMREL----PEF .| ... || | ||| .. ...|.|||||| | . ... .||.. | ..|. . .. || .|| . | |.. |. slrvtseadqGgrkymeDvvaivlereesaeeaeaafvavfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkklaeWpkt TRESEKCGGTTAVCAFVGLTQVYIANCGDSRAVLCRQGV------PVFATQDHKPILPEEKERIYNAGGSVMIK .. |||| . .. ...|.|. |||..|| . . |.|||| ||||||| ..||.|..| ksgllstaGttasvviirreklyvahvGDsgivlgvkepkekklrakeltkdHkPespeEkerieelGGevaak |
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| Phosphatase | alph.AA | Subfamily.PDP.PD | 118-265 | 31 | 2.4e-21 | 66.7 | In-house | 164-340 (409) | Show / Hide |
Range on Protein: 118-265
Range on HMM: 164-340/409
Sequence Identity: 31% (55 aa)
CGGTTAVCAFVGLTQVYIANCGDSRAVLCRQ---G--VPVFATQDHKPILPEEKERIYNAG---GS---VMIKRVNGTLAVSRALGDYDFKNVKEKGQCE
. |..|..|.. |....|| ||.||||..| | .| ..|. .|| ||| .. | .. .|. |.|| .|| ||. .||| .
lsGacallaliegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikkeHPgeesktvirngRlLgeLaPlRAFGdvryKwskelqkkv
-------QLVSP-----------EPEIFCQSRQDSDEFLVLACDGIWDVMSNEDVCSFIHSRMRVTSNLVSIANQVV
. | | |||.. . . .| ||||| ||.||..|||.| | .. . ..| ..|.. .
lekllevkvvepkdyktPPYltaePevtshklrendkFLvlatDGLwdllsneevvslVgehlakkknkakvaaepa
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| Phosphatase | alph.AA | Subfamily.PPM1G.PD | 16-106 | 36 | 5.2e-21 | 65.5 | In-house | 4-91 (482) | Show / Hide |
Range on Protein: 16-106 Range on HMM: 4-91/482 Sequence Identity: 36% (33 aa) EGEGNKLLFGVSSMQGWRSEMEDAYYAragLGDALPDWSFFAVFDGHAGCKVSEHCAKHLLESIISTEEFIGGDHVKGIRTGFLRIDEVMR .. ..| .|.|.||||| .||||. . . | |.|.|||.||| | |...|||.| . . .. . || |... || .|. .. desneelsygasamqGWRvsmeDahnc---ildldedtslfavyDGhGGkevakycakklPdllkeskaykegdvekaleeaflkvDkkll |
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| Phosphatase | alph.AA | Subfamily.TAB1.PD | 114-268 | 25 | 5e-16 | 48.6 | In-house | 132-307 (336) | Show / Hide |
Range on Protein: 114-268
Range on HMM: 132-307/336
Sequence Identity: 25% (43 aa)
ESEKCGGTTAVCAFVGLTQVYIANCGDSRAVLCRQG----VPVFATQDHKPILPEEKERIYNAG---GSVMIKRVNGTLAVSRALGDYDFKNVKEKGQCE
||| |||||| | . . |.||.|||||.|... . .|| ..| .|. . | . . .. | |..||| |.. . .
eseisgGttavvalilnnkLyvaNvGdsrAilvesekdgikvkQLsvdHnvdNedElkRlkdLGldieqikqnkrlgskeaTRsiGdykikkgykevdvl
QL-----VSPEPEIFCQSRQDSDE-FLVLACDGIWDVM--------SNEDVCSFIHSRMRVTSNLVSIANQVVDTC
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ssAkgePiiatPdingpkdindlegfllLmSdGlykalieltnpptadvslallviqeaeksatlddvaqavvdrv
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| Phosphatase | alph.AA | Subfamily.PPM1H.PD | 179-253 | 35 | 6e-15 | 45.1 | In-house | 277-355 (402) | Show / Hide |
Range on Protein: 179-253 Range on HMM: 277-355/402 Sequence Identity: 35% (27 aa) KRVNGTLAVSRALGDYDFKNVKEKGQCEQLVSPEPEIFC----QSRQDSDEFLVLACDGIWDVMSNEDVCSFIHSRMRV .|. .|..|.| |||.. | |... . ..||.||. | ...|. |.|| ||.|||.|||.| ... . aRllatigvtRGlGDheLkvvdtnlsikPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivrevlsk |
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| Phosphatase | alph.AA | Subfamily.PPM1D.PD | 185-282 | 31 | 5.3e-14 | 42.2 | In-house | 207-311 (311) | Show / Hide |
Range on Protein: 185-282 Range on HMM: 207-311/311 Sequence Identity: 31% (34 aa) LAVSRALGDYDFKNVKEKgqcEQLVSPEPEIFCQSRQDSDE-FLVLACDGIWDVMSNEDVCSFIHSRMRVTSN----LVSIANQVVDTCLHKGSR----- |||.|.||| | | . | .|||||.. . .. ..| |..|| ||.|.|.. ||. |.... ... |.|...|.. |.. .. LavaRslGDlWsynaksg---eyvvsPePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkelkeeqsrsvakalvkealqrwrskklra DNMSIIII ||.|.|.. Dnvsvivv |
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| Phosphatase | alph.AA | Subfamily.PHLPP.PD | 133-282 | 23 | 2.6e-12 | 36.5 | In-house | 119-257 (257) | Show / Hide |
Range on Protein: 133-282 Range on HMM: 119-257/257 Sequence Identity: 23% (36 aa) VYIANCGDSRAVLCRQGVPVFATQDHK-PILPEEKERIYNAGGSVMI-KRVNGTLAVSRALGDYDFKnvkekgqceQLVSPEPEIFCQSRQDSDEFLVLA . || |. ..||.|.| |. .. . | .|| .|| .| . . .||| .. .| || . | |.|.. .. ||.|.| ltaanvgkcklvlirnGkplplskvyileiddeelkrikeakaiitednkvnGviestrilGytflf---------PvvlPkphvrsvlLteqdEllilG CDGIWDVMSNEDVCSFIHSrmrvTSNLVSIANQVVDTCLHKGSRDNMSIIII ...|.|.| ... . .. . . .| ..|| | .|..|.... nkalWevlsideaveavrn----vedplvaAkklvdlaqsygaadsvsalvv |
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| Phosphatase | alph.AA | Subfamily.PPM1H.PD | 93-169 | 34 | 3e-11 | 32.9 | In-house | 141-212 (402) | Show / Hide |
Range on Protein: 93-169 Range on HMM: 141-212/402 Sequence Identity: 34% (26 aa) GIRTGFLRIDEVMRElpEfTRESEKCGGTTAVCAFVGLTQVYIANCGDSRAVLCRQGVPVFATQDHKPIlpEEKERI . . ||..||.... | .. .. || ||. | | | ..|.|| |||||.|.|.. . .|. | |..|. alesaflemDeqiar--e-reayrikGGCtalvalvllgklYvanaGDsRailvrkdeiiplsadftPe--teRqRl |
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