Gene Ppm1
Ppm1
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of Ppm1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
---|---|---|---|---|---|---|---|---|---|
Phosphatase | Ppm1.AA | Family.PPM.PD | 12-299 | 40 | 8.3e-95 | 308.1 | In-house | 5-299 (495) | Show / Hide |
Range on Protein: 12-299 Range on HMM: 5-299/495 Sequence Identity: 40% (123 aa) KDTACCANASYRVGSSCMQGWRVDMEDAHTHILSLPDDPQAAFFAVYDGHGGASVAKYAGKHLHKFITKRPEYRD------------NSIEVALKKAFLD ..| . . ..|.|.. ||||| .|||||. . .| .... ..|.|.||||||..|..| |.|||...|. |. | .... ||.||||. arteasssnglrygvasmqgwrsemeDahvvvenlennedfslfgvfDGhgGaeaaefaakklhkilkkqlekkddeksstsaessaekvkealrkafle FDREMLQNGSLDE--QTAGCTAIVVLIRERRLYCANAGDSRAIACISGMVHALSVDHKPNDAKESKRIMASGGWVEF--NRVNGNLALSRALGDFIYKKn |.|. .. . .. ...|.||.|||||...||.||||||||. | .| ...|| ||||.. .| .|| ..||.|. .|||| ||.||||||| .|| ldeelseelneksagkdsGtTAvvvlirgkklyvAnaGDsravLcrngkavelskdHkpenpeEreRIekagGkvvirdgrvnGvlavsRalGdfdlkk- llktpEEQI-VTAYPDVEVLDIT-EDLEFVLLACDGIWDVMSNFEVCQFVHKRI-RDGMEPELICEELMNSCLSPDGHtgnvggDNMTVILVCLLHNKSY |||. |.| ||. ....| |. ||. ||.||.|||.|| ||...|.... ... ..| |.|||....|... . ||.||..|.| .| -----eeqaivsaePditsvkltqeedeflvlasdGlWdvlsneevvelvretleekeedleeiaeeLvdealakgsr------DNiTvlvvalyenikq EDLAVRC .. .|. qnrfvln |
|||||||||
Phosphatase | Ppm1.AA | Subfamily.PPM1G2.PD | 14-284 | 56 | 9.69999999999e-132 | 428.3 | In-house | 2-275 (275) | Show / Hide |
Range on Protein: 14-284 Range on HMM: 2-275/275 Sequence Identity: 56% (153 aa) TACCANASYRVGSSCMQGWRVDMEDAHTH---ILSLPDDPQAAFFAVYDGHGGASVAKYAGKHLHKFITKRPEYRDNSIEVALKKAFLDFDREMLQNGSL ....|||...||.|.|||.|..|||||.. .|...||...|.|||.||||||.|||||||.|.|.|.|.........| .||.|||..|.|.|.. .| assganariavgvssmqGyrlnmeDahilenelleksddkslalfavfDGhGGakvakyagkklikkiakkksfkegaleqilkdafletDeellkdekl DEQTAGCTAIVVLIRERRLYCANAGDSRAIACISGMVHALSVDHKPNDAKESKRIMASGGWVEFNRVNGNLALSRALGDFIYKKNLLKTPEEQIVTAYPD ....||.||.||||.|..||.||||||||.....|.|.|||.||||....|.|||.|.||.||.||||||||||||||||.||| |.||||||||.||| kdesaGstavvvlikeeklyvanaGDsravlsskgnvkalsfDhkPqeesekkriiaagGfvelnrvngnLalsralgDfefkknvkkkpeeqivtavPD VEVLDITEDLEFVLLACDGIWDVMSNFEVCQFVHKRIRDGMEPELICEELMNSCLSPDGHTGNVGGDNMTVILV .| ...|| ||..|||||||||..| ||...|..|...|.... |.|||...||.|| ....|| |||||..| vlvkkldeddeflvLaCDGiWDvltnkevvdlvrerlvsgakldeiieelldkclapdssntgvGcDnmtvviv |
|||||||||
Phosphatase | Ppm1.AA | PP2Cc | 13-284 | 30 | 1.4e-100 | 341.32 | SMART | 1-338 (338) | Show / Hide |
Range on Protein: 13-284 Range on HMM: 1-338/338 Sequence Identity: 30% (113 aa) DTACCANASYRVGS--SCMQGWRVDMEDAHTHILSLPDDPQAAFFAVYDGHGGASVAKYAGKHLHKFITKRPEYRDN----------------------- . . |...|.| |.|||||. ||||| .. ||.|.||||| ..|.|..||||... . .. . HS-MGYNSGWRYGYMESSMQGWRHPMEDAHVCRP---------FFGVFDGHGGHECAQYCRKHLHEHLAEELQFHKDDDYKENDEMQDEPEMWWRMWHDK ---SIEVALKKAFLDFDREMLQNGSLDEQTAGCTAIVVLIRERRLYCANAGDSRAIACISGM----------VHALSVDHKPNDAKESKRIMASGG---- ..| ||.|||| | |. |||.|.|||. .||.||.|||||. | .| .|.|..||||....| .|| ..|| WFEDWEDALRKAFLRMDEEI------------CTAVVALIRGNKLYVANVGDSRAVLCRNGNDNWWGIRHYTAHQLTEDHKPDNEDERRRIEQAGGRVMP ----WVEFN-----RVNGN---LALSRALGDFIYKKNL----------------LKTPEEQIVTAYPDVEVLDI------TEDLEFVLLACDGIWDVMSN ||... ||||. ||.|||.||. ||. . ..|..|.| |||.. .. |.| .|..|.|||.|||||| MHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKW-KEDEKIEWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQMTVPTPDDDFLILCCDGLWDVMSN FEVCQFVHKRI-----------------------RDGMEPELICEELMNSCLSPDGHTGNVGGDNMTVILV ||...|.|.. . ..|. ....|.. .. ||||||.| QEVVDIVRKCLRKWHHKPVKNQAQENAHMMRHRQKKHNDPMEAAKRLCDCAI----------CDNMTVIVV |
|||||||||
Phosphatase | Ppm1.AA | Group.PPM.PD | 16-297 | 37 | 9.1e-100 | 324.5 | In-house | 32-332 (459) | Show / Hide |
Range on Protein: 16-297 Range on HMM: 32-332/459 Sequence Identity: 37% (117 aa) CCANASYRVGSSCMQGWRVDMEDAHTHILSLPDDPqaAFFAVYDGHGGASVAKYAGKHLHKFITKRPEYRD------------------NSIEVALKKAF . . .|.|...||||| .|||.|. .... ... .||.|.||||||..|..| |.|.|...|. .. . .... ||..||| agsgnglrygvasmqgwrkemEDrhvivenfdnnd--sffgVfDGHgGaeaaefaakkLpkilkkqlkkkkdevskksaeasldnddrgekvkkalrsaf LDFDREMLQNGSLDE---QTAGCTAIVVLIRERRLYCANAGDSRAIACISGMVHALSVDHKPNDAKESKRIMASGGWVEF-NRVNGNLALSRALGDFIYK ..|... .. . .| ...|.||.|.||... ||.||||||||. | .| ...|| ||||.. .| .|| ..||.|| .|||| ||.||||||. .|| leldedlseeanekeepgkdsGtTAvvalingkklyvANaGDSravLcrngkavplskdHkpenpeEreRIekagGsveidgRvnGilavsRalGdhdlk KnllktpEEQIVTAYPDVEVLDITEDLEFVLLACDGIWDVMSNFEVCQFVHKRIRD-----GMEPELICEELMNSCLSP-DGhTGNVGGDNMTVILVCLL |||.|.| ||| |...||. ||. ||.||.|||.|| ||..||.... . . ..| |.|.|....|.. . . . ||.|||.|.| . k------eeqmvsaePdvsvvklteedeflvlAsDGlWdvlsneevvefvretlekkkkelkkdleeiaerlvdealakgst-gdgtscDNiTvivvtln HNKSYEDLAV .. .. .| damrrqleiv |
|||||||||
Phosphatase | Ppm1.AA | PP2C | 22-274 | 40 | 7.7e-95 | 326.18 | Pfam | 1-284 (284) | Show / Hide |
Range on Protein: 22-274 Range on HMM: 1-284/284 Sequence Identity: 40% (116 aa) YRVGSSCMQGWRVDMEDAHTHILSL----PDDPQAAFFAVYDGHGGASVAKYAGKHLH----KFITKRPEYRDN---SIEVALKKAFLD--FDREMLQ-- ...|...||||| |||||... .. ... .||||.|||||. .|||..|||| .. .|..... | ||.|.|| .| .. . WDYGFCRMQGWRHFMEDAHHCYPNMNCSSSGKDSWHFFAVFDGHGGHQAAKYCRKHLHKAMNTILKERKSFPEGNPKDVEQALRKSFLECDTDMMFYSAP --NGS-LD--EQTAGCTAIVVLIRERR--LYCANAGDSRAIACISGMVH----ALSVDHKPNDAKESKRIMASGGWVE---FNRVNGN-LALSRALGDFI . . .. .. ||||....||. . ||.||.|||||. |..| .| .|..||||.. .| .|| ..||||. |.||||. ||.|||.||| WHEQNVMHWECWHSGCTAVCAYIRNQKNILYVANCGDSRAVLCRNGNAHNWVHQLTYDHKPSNEDERRRIRQAGGWVMWWGFWRVNGVWLAVSRAFGDFH YKKNLLKTPEEQIVTAYPDVE-VLDITED-LEFVLLACDGIWDVMSNFEVCQFVHKRIRDGMEPELICEELMNSCLSPDGHTGNV ||.| . |.||.||| ||.. . .||.| ||..|||||.|||||. |||..|.... |. |...||.|.. |... | . |. YKPNHTCFPKEQPVTAEPDITPEHKITPDHDEFLILACDGLWDVMSDQEVCDIVRQCRSDWNDPMEACEKLVDYCIAY-GSEDNI |
|||||||||
Phosphatase | Ppm1.AA | Subfamily.PPM1A.PD | 19-296 | 43 | 5.5e-94 | 304.9 | In-house | 7-288 (309) | Show / Hide |
Range on Protein: 19-296 Range on HMM: 7-288/309 Sequence Identity: 43% (125 aa) NASYRVGSSCMQGWRVDMEDAHTHILSLPD-DPQAAFFAVYDGHGGASVAKYAGKHLHKFITKRPEYR-------DNSIEVALKKAFLDFDREMLQNGSL ....|.| | |||||| |||||| ...||. .. .||||.|||.|..|.||..|||.. |.. |.. .... ||.|.||..|.. .. .|. gnglryglssmqgwRvemEDahtavidlpsklkdwsffavfDGHaGskvskycakhlleaileeeefkaskeksskekvkealrkgfLelDekirklvel D--EQTAGCTAIVVLIRERRLYCANAGDSRAIACISGMVHALSVDHKPNDAKESKRIMASGGWVEFNRVNGNLALSRALGDFIYKKNLLKTPEEQIVTAY |. .|.||.|||.... ||.||.|||||. . | |. . |||| |.|| .|| . || | .||||.||.||||||.||.. |...||.|.. |. skgedksGsTavvvlvspkklylancGDsRavlsrngkvvfateDHkpsdpkEkeRienAgGsvmikRvnGsLAvsRalGDydykekpekkateqlvspe PDVEVLDITEDLEFVLLACDGIWDVMSNFEVCQFVHKRIRDGMEPELICEELMNSCLSPDGHtgnvggDNMTVILVCLLHNKSYEDLA | |....|. ||..|||||||||||| ||..||..|.. . ..| ...||.. ||. . . |||.||||.| .. | pevtvierdeedeflvlacDGiwDvmsneevaefvksrlevtddleevanelldtcLekgsr------DNmsvilvllpgapkvseea |
|||||||||
Phosphatase | Ppm1.AA | Subfamily.PPM1G.PD | 114-284 | 48 | 1.2e-64 | 209.4 | In-house | 306-480 (482) | Show / Hide |
Range on Protein: 114-284 Range on HMM: 306-480/482 Sequence Identity: 48% (84 aa) TAGCTAIVVLIRERRLYCANAGDSRAIACISGMVHALSVDHKPNDAKESKRIMASGGWVEF-NRVNGNLALSRALGDFIYKKNLLKTPEEQIVTAYPDVE .|.||.| |.....|. |||||||.. . .| ||.||||.| .| .|| . || |. |||| | ||||||| .||.| .|||...|.||. . dsGttavvaLvkgkklivanaGDsRcvlsrnGkaldlsiDhkPeDeveleRiekaGGkvtldgRvnGGLnlsRalGDhaYktneeLpaeeqmisalPDik VLDITEDLEFVLLACDGIWDVMSNFEVCQFVHKRIRDGMEP---ELICEELMNSCLSPDGHTGNVGGDNMTVILV | .||. ||. |||||||.||| || .||....... | |||||.. ||.|| . | |||||..| klilteedeFlvlacDGiWnvmssqevvdFvraklkeseeskklseiceeLlDaCLapdtsgDGtGCDnmtvviv |
|||||||||
Phosphatase | Ppm1.AA | Subfamily.PPM1E.PD | 18-285 | 34 | 1.9e-58 | 187.9 | In-house | 7-268 (269) | Show / Hide |
Range on Protein: 18-285 Range on HMM: 7-268/269 Sequence Identity: 34% (93 aa) ANASYRVGSSCMQGWRVDMEDAHTHILS------LPDDPQAAFFAVYDGHGGASVAKYAGKHLHKFITKRPEYRDNSIeVALKKAFLDFDREMLQNGSLD . | | . .... | ||| | . . | |... |||||.||||| |||| .|||... .... ... |||.|| |..|| . .. sqkeyevsiaavknkrrkmEDrhvaledlnelfelkdekeraffavfDGHgGveaakyaaahlhellvrqeklkedpa-ealkeafkltDerflqkaere EQTAGCTAIVVLIRERRLYCANAGDSRAIACISGMVHALSVDHKPNDAKESKRIMASGGWV---EFNRVNGNLALSRALGDFIYKknllktpeeQIVTAY ..|.||.||||....|| | |||.|. . | . | |||.. .| ||| . || | . ||||.|..|||.||.| . |.. .|| klksGstavvvliekdqlyvaWlGDsqallvrkgeavqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRaiGDvklk---------pyvsge PDVEVLDITEDLEFVLLACDGIWDVMSNFEVCQFVHKRIRDGM-EPELICEELMNSCLSPDGHtgnvggDNMTVILVC ...... ....|||||.|||. . ||.. |.. ..|| . . . ..|... . . . ||.||..| advaeveldgsedylilacDGlwDvvneeevvklveefladgaedlsevakllveaakeagss------Dnitvvvvf |
|||||||||
Phosphatase | Ppm1.AA | Subfamily.LRR-PP2C.PD | 20-284 | 37 | 1.9e-47 | 151.9 | In-house | 8-255 (257) | Show / Hide |
Range on Protein: 20-284 Range on HMM: 8-255/257 Sequence Identity: 37% (97 aa) ASYRVGSSCMQGWRVDMEDAHTHILSLPDDPQAAFFAVYDGHGGASVAKYAGKHLHKFITKRPEYRDNSIEVALKKAFLDFDREMLQNGsldeQTAGCTA ..|| | | | | ||| . | |... ..|..||||| . ||.| ..|.| ... . . . . .||||. . . . .. . |.||..| srfkvgfsdmiGrrptmedelviyGsfrdksdedyyalfdGhgGraaakfaseelykilaelldlnnanPlkslkkaykeistqiserp----kfiGtta IVVLIRERRLYCANAGDSRAIAC-ISGMVHALSVDHKPNDAKESKRIMASGGWVEFN----RVNGNLALSRALGDFIYkknllkTPeeqIVTAYPDVE-V || | . | || ||||.. | |. . ||.||||.. .| ||| . || | . ||||.||.||||||.| |.. ||.. |.|... .|..| asvliiedkvyianvGdsrvvlcqkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGdsfl------eP---fvvpdPdlsqs LDITEDLEFVLLACDGIWDVMSNFEVCQFVHKrIrdgMEPELICEELMNSCLSpDGHTgnvggDNMTVILV |||||||..|. | .. | . | .|| .|.| . | | | ||..||.. leiskkdkflilacdGiwdlisdeeaveivag-i---sdpekaaeklrdlays-sGst-----dnisvivi |
|||||||||
Phosphatase | Ppm1.AA | Subfamily.ILKAP.PD | 24-250 | 33 | 6.3e-47 | 150.4 | In-house | 11-255 (298) | Show / Hide |
Range on Protein: 24-250 Range on HMM: 11-255/298 Sequence Identity: 33% (83 aa) VGSSCMQGWRVDMEDAHTHILSLPDD--------PQAAFFAVYDGHGGASVAKYAGKHLHKFIT-----KRPEYRDNSIEVALKKAFLDFDREMLQNGSL . .. .| | .|||||. . | .. .....||.|||.| ...| ..||| | . .|..|. .| .|| |.|.|.. | . gafaerkGereemeDahvilndldeqtrkekskvsrvsyyavfDGhaGsrasefaaeklhkviveklpkedvsakdkeikkclvdafkktDeeflklask D--EQTAGCTAIVVLIRERRLYCANAGDSRAIACISG-----------MVHALSVDHKPNDAKESKRIMASGGWVEFNRVNGNLALSRALGDFIYKKNLl |.||.|||. . || || |||.|. . .. ||.||.| . .| ||| .|| |...||.||. ||..|| .|. akPvWkdGstavvvlvvdnvlyvanlGDskavlaRakeegdkagestiasvlLskdHtpasyeerkriqkaGgvvrdgRvlGvlevsRsiGDgrfkelg- ktpeeqiVTAYPDVEVLDITEDLEFVLLACDGIWDVMSNFEVCQFVHKRIRDG |.. |||. ...||. ||.|||||.|.|... || .|. | . | -------vistPdvkkceLtenDlfvvlaCDGLwkvfeadevvkfilkvlede |
|||||||||
Phosphatase | Ppm1.AA | Subfamily.PPM1L.PD | 25-255 | 37 | 1.2e-46 | 149.5 | In-house | 15-248 (273) | Show / Hide |
Range on Protein: 25-255 Range on HMM: 15-248/273 Sequence Identity: 37% (86 aa) GSSCMQGWRVDMEDAHTHILSLPDDPQAAFFAVYDGHGGASVAKYAGKHLHKFITKRP-E---YRDNSI----EVALKKAFLDFDREMLQNGSLDEQTAG ...| | ||| . . .. . ||||.||||| |..| . | | | .. | ..|.. . |.. | |...|..|..||.||.. | avysvlGrrprmedrfeieediknktgesffavfdGhGGefaaefakdvlvkaiknklieldadkentvpinfsklltdeilsvdekllekakraediaG CTAIVVLIRERRLYCANAGDSRAIAC-ISGMVHALSVDHKPNDAKESKRIMASGGWVEFN---RVNGNLALSRALGDFIYKknllktpEEQIVTAYPDVE ..|. | || |||| . . .|. || ||||.. || ||| .||.. |. ||.| ||.||||||. |....| | ||. .|. . . ||..| ttalialvqesdlivanvGdsrGvlydkrGkaiplsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdyplk-------dknlviadpdil VLDITE-DLEFVLLACDGIWDVMSNFEVCQFVHKRIRdgmEPEL |.||.|| .|| | ..|...|. ||.. tfdlddhkpeflilasdGlwdtfsneeavrfikerlk---epdf |
|||||||||
Phosphatase | Ppm1.AA | Subfamily.PPM1K.PD | 23-247 | 33 | 3.8e-43 | 137.7 | In-house | 11-235 (264) | Show / Hide |
Range on Protein: 23-247 Range on HMM: 11-235/264 Sequence Identity: 33% (77 aa) RVGSSCMQGWRVDMEDAhTHILSLpdDPQAAFFAVYDGHGGASVAKYAGKHLHKFITKRPeYRDNSIEVALKKAFLDFDREMLQNGSLD-----EQTAGC .|| ..| | || ... | ||. .|||.|||||.| | .. ..|.. . . ... .| ||.||.. |... . .....| || |.| svGkdsliGkraenedr-fklkel--dpdllyfavfdGhgGssaadfvhdkleeivrrll-ekekdleevlkqafeeldkklkrylefsvaeaellssGt TAIVVLIRE-RRLYCANAGDSRAIACISGMVHALSVDHKPNDAKESKRIMASGGWVEFN-----RVNGNLALSRALGDFIYKKnllktpeeQIVTAYPDV .|. | |. |||||| | | . |. ||.|. .| .|| |.|| ||.| .||. ||..|.|||. |. | | |. |.. tatvsllrdGnelvlaslGdsrailcrnGkakkltkdhdPerkeekerikaagGsvewnslgkplvnsrlamtrslGdldlkr--------yGviatPet EVLDI-TEDLEFVLLACDGIWDVMSNFEVCQFVHKRI .. |..| ||| .|... |.|..|.. kslkvkhaadsflvlitdgisfvvnsqelcdlvrlch |
|||||||||
Phosphatase | Ppm1.AA | Subfamily.PPM1G.PD | 19-112 | 46 | 1.1e-31 | 100.6 | In-house | 7-98 (482) | Show / Hide |
Range on Protein: 19-112 Range on HMM: 7-98/482 Sequence Identity: 46% (44 aa) NASYRVGSSCMQGWRVDMEDAHTHILSLPDDpqAAFFAVYDGHGGASVAKYAGKHLHKFITKRPEYRDNSIEVALKKAFLDFDREMLQNGSLDE | . .| | ||||||.|||||. || | .| ..|||||||||. ||||. |.| ...... |... .|.||..|||..|...|.. .|.| neelsygasamqGWRvsmeDahncildlded--tslfavyDGhGGkevakycakklPdllkeskaykegdvekaleeaflkvDkkllteeilke |
|||||||||
Phosphatase | Ppm1.AA | Subfamily.PPM1D.PD | 21-174 | 35 | 1.3e-31 | 100.1 | In-house | 7-179 (311) | Show / Hide |
Range on Protein: 21-174 Range on HMM: 7-179/311 Sequence Identity: 35% (60 aa) SYRVGSSCMQGWRVDMEDAHTHILSLPD---DPQAAFFAVYDGHGGASVAKYAGKHLHKFITKRPEYR---DNSIEVALKKAFLDFDREMLQN------- | || |.. || | ||| . |. . . .|||.||.||||| ||.| .|| ..|.|. .. .... |...|||. ..|.. slrvtseadqGgrkymeDvvaivlereesaeeaeaafvavfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkklaeWpkt GSLDEQTAGCTAIVVLIRERRLYCANAGDSRAIACISGM------VHALSVDHKPNDAKESKRIMASGGWVEF | . ||| || ||.||...|| |. |||... .. . | .||||.. .| .|| .|| | ksgllstaGttasvviirreklyvahvGDsgivlgvkepkekklrakeltkdHkPespeEkerieelGGevaa |
|||||||||
Phosphatase | Ppm1.AA | Subfamily.PDP.PD | 86-253 | 28 | 9.6e-22 | 67.9 | In-house | 124-332 (409) | Show / Hide |
Range on Protein: 86-253 Range on HMM: 124-332/409 Sequence Identity: 28% (59 aa) DNSIEVALKKAFLDFDREML-------QNGSLDEQ-----TAGCTAIVVLIRERRLYCANAGDSRAIACIS---G--MVHALSVDHKPNDAKESKRIMAS ....| |||||||..|... .. .|.|. ..| .|...||... |. ||.||.||. . . | . .|| |. . ..|.|| . elkveealkkaFlrlDkdislealkkleekvleeavlkvalsGacallaliegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikke G------GWVEFNRVNGNLALSRALGDFIYKK--NLLKTPEEQ----------------IVTAYPDVEVLDITEDLEFVLLACDGIWDVMSNFEVCQFVH . .|. |.|| .|| ||. || .| |. |. .|| |.| ..|. |..|| ||.||..|| || . |.. HPgeesktvirngRlLgeLaPlRAFGdvryKwskelqkkvlekllevkvvepkdyktPPYltaePevtshklrendkFLvlatDGLwdllsneevvslVg KRIRDGMEP . . .. ehlakkknk |
|||||||||
Phosphatase | Ppm1.AA | Subfamily.TAB1.PD | 114-236 | 35 | 1.3e-18 | 57.2 | In-house | 136-271 (336) | Show / Hide |
Range on Protein: 114-236 Range on HMM: 136-271/336 Sequence Identity: 35% (46 aa) TAGCTAIVVLIRERRLYCANAGDSRAIACISG----MVHALSVDHKPNDAKESKRIMASG---GWVEFNRVNGNLALSRALGDFIYKK-----NLLKTPE | ||.|.|| || || ||||||.. | |. ||||| . .| ||. | . . |.. |. |..||. ||..|. ... . | sgGttavvalilnnkLyvaNvGdsrAilvesekdgikvkQLsvdHnvdNedElkRlkdLGldieqikqnkrlgskeaTRsiGdykikkgykevdvlssAk EQIVTAYPDVEVLDITEDLE-FVLLACDGIWDVMSN ||.. . .||| |.|| ||. . . . gePiiatPdingpkdindlegfllLmSdGlykalie |
|||||||||
Phosphatase | Ppm1.AA | Subfamily.PPM1H.PD | 89-161 | 36 | 1.6e-18 | 56.8 | In-house | 138-210 (402) | Show / Hide |
Range on Protein: 89-161 Range on HMM: 138-210/402 Sequence Identity: 36% (27 aa) IEVALKKAFLDFDREMLQNGSLDEQTAGCTAIVVLIRERRLYCANAGDSRAIACISGMVHALSVDHKPNDAKE . || .|||. | . .. . ... ||||.|.|. . .|| ||||||||| . .. ...|| |. |. .. viGalesaflemDeqiarereayrikGGCtalvalvllgklYvanaGDsRailvrkdeiiplsadftPeteRq |
|||||||||
Phosphatase | Ppm1.AA | Subfamily.PHLPP.PD | 18-245 | 22 | 5.5e-12 | 35.5 | In-house | 6-228 (257) | Show / Hide |
Range on Protein: 18-245 Range on HMM: 6-228/257 Sequence Identity: 22% (52 aa) ANASYRVGSSCMQGWRVDMEDAHTHILSLPDDpQAAFFAVYDGHGGASVAKYAGKHLHKFITKRPEYRDNSiEVALKKAFLDFDREMLQNGsldeQTAGC |.| ...| | ..| . . | . .. .. . | . ..|| ... . . .... . | || ... .| .|.. ..|| |..|.. asavfshGlseaaGvknklCvaalavenfaen-veavyGlidGdrnselpsllqctmadvlkeevqkdkne-evyianillvshrklGeaG----qklGa TAIVVLIRERRL--------YCANAGDSRAIACISGMVHALSVDHK-PNDAKESKRIMASGGWV-EFNRVNGNLALSRALGDFIYKKnllktpeeqIVTA . |.| |. .||.|. ... ...| || . | .| ||| . . | |.||| .. .| ||. .| | |. sallirikedrvdiassftltaanvgkcklvlirnGkplplskvyileiddeelkrikeakaiitednkvnGviestrilGytflfP---------vvlP YPDVEVLDITEDLEFVLLACDGIWDVMSNFEVCQFVHK . .||. |...| ...|.|.| |. . |.. kphvrsvlLteqdEllilGnkalWevlsideaveavrn |
|||||||||
Phosphatase | Ppm1.AA | Subfamily.PPM1D.PD | 181-282 | 26 | 2.5e-10 | 30.2 | In-house | 207-309 (311) | Show / Hide |
Range on Protein: 181-282 Range on HMM: 207-309/311 Sequence Identity: 26% (28 aa) LALSRALGDFIYKKnllKTPEEQIVTAYPDVEVLDITEDLE-FVLLACDGIWDVMSNFEVCQFVHKRIRDGME----PELICEELMNSCLSPDgHTGNVG ||..|.|||. . .. .| .| ||| | .. . | |..|| ||.|.|.. .. ..|.| .. . . . |... |... .. || LavaRslGDlWsyn---aksgeyvvsPePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkelkeeqsrsvakalvkealqrw-rskklr GDNMTVI ..|| aDnvsvi |
|||||||||
Phosphatase | Ppm1.AA | Subfamily.PPM1H.PD | 176-247 | 31 | 1.7e-08 | 23.8 | In-house | 278-353 (402) | Show / Hide |
Range on Protein: 176-247 Range on HMM: 278-353/402 Sequence Identity: 31% (24 aa) RVNGNLALSRALGDFIYKKNLLKTPEEQIVTAYPDVEVLDITE----DLEFVLLACDGIWDVMSNFEVCQFVHKRI |. . .. .| ||| | . .... |.|.|||.|. . . ..|| ||.|||.|| || . |.. . RllatigvtRGlGDheLkvvdtnlsikPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivrevl |
|||||||||
Phosphatase | Ppm1.AA | Subfamily.PPM1H.PD | 50-81 | 38 | 2.2e-06 | 16.9 | In-house | 62-93 (402) | Show / Hide |
Range on Protein: 50-81 Range on HMM: 62-93/402 Sequence Identity: 38% (12 aa) PQAAFFAVYDGHGGASVAKYAGKHLHKFITKR . |.|...|||.| ..| | | ||| .... lplayfglfDGhaGsgaalvaskllhkhlkek |
|||||||||
Phosphatase | Ppm1.AA | Subfamily.PDP.PD | 36-80 | 33 | 7.7e-06 | 15.6 | In-house | 23-65 (409) | Show / Hide |
Range on Protein: 36-80 Range on HMM: 23-65/409 Sequence Identity: 33% (15 aa) MEDAHTHILSLPDDpqAAFFAVYDGHGGASVAKYAGKHLHKFITK .|| .. .| . . .|.| |||||| |. |.| |.... iEDrrseakllesn--gvlfgvfDGHggaacaeavskrLlkyvaa |