Gene CG15035
CG15035
Species: D.melanogaster
Alias: CG15035
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of CG15035.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | CG15035.AA | PP2Cc | 110-371 | 11 | 7.7e-09 | 35.84 | SMART | 1-338 (338) | Show / Hide |
Range on Protein: 110-371
Range on HMM: 1-338/338
Sequence Identity: 11% (45 aa)
VSVTCGFAKDHIRY--PEY-NRGKFGEDAWFMSSSPQACIMGVADGVGGWRNYGVDPGKFSMTLMRSCERMSHAPDFKPNR-------------------
.| ... .. . | . .. . .|||... ..||.|| | . .... . | . ..|. .
HS-MGYNSGWRYGYMESSMQGWRHPMEDAHVCRP-----FFGVFDG-----HGGHECAQYCRKHLH--EHLAEELQFHKDDDYKENDEMQDEPEMWWRMW
-------PEILLERAYFDLLDQKCPIVGSCTACILALKRDDSTLYAANIGDSGFLVVRSGK----------VVCRSQEQQH-------------------
.| .|..|.. . .. |||... .. .. || ||.||| . |.|. .. .... .
HDKWFEDWEDALRKAFLRMDEEI------CTAVVALIRGNK--LYVANVGDSRAVLCRNGNDNWWGIRHYTAHQLTEDHKPDNEDERRRIEQAGGRVMPM
-------------QFNTP---YQLASPPPGYDFD-------------------------AVSDGPESADTIQF----PMQLGDVILLATDGVYDNVPESF
.| ... ... .|. |. .. | . .| ..|..||..|....
HRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKWKEDEKIEWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQMTVPTPDDDFLILCCDGLWDVMSNQE
LVEVLTE--MSGISNPV-------------------RLQMAANTVALMARTLSFSPKHDSPFSQNARKHDIDAWGGKPDDITVLLA
.|..... ..... || ...||. .. .|. |..||..
VVDIVRKCLRKWHHKPVKNQAQENAHMMRHRQKKHNDPMEAAKRLCDCAI---------------------------CDNMTVIVV
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| Phosphatase | CG15035.AA | Family.PPTC7.PD | 111-373 | 55 | 1.3e-127 | 414.4 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 111-373 Range on HMM: 1-262/262 Sequence Identity: 55% (146 aa) SVTCGFAKDHIRYPEYNRGKFGEDAWFMSSSPQACIMGVADGVGGWRNYGVDPGKFSMTLMRSCERMSHAPDFKPNRPEILLERAYFDLLDQKCPIVGSC .|.||||||........|.||||||.|.||...|...||||||||||.||||...||..||..|||......|||..|. ||..||..||..|.|.|||. avkcgfakdllkqkskkrskfGeDayFvssnkvadvlgvADgvggwreygvdssafsselmkkcerlvkeskfkplkpkkllkaayaelleekvpvvGss TACILALKRDDSTLYAANIGDSGFLVVRSGKVVCRSQEQQHQFNTPYQLASPPPGYDFDAVSDGPESADTIQFPMQLGDVILLATDGVYDNVPESFLVEV |||...|.|.|..|..||.|||||||||.||||.||.||||.|||||||. ||...| ...|| ||.||...|... ||.||||||||.||..|. ..|. tAcvvvldredkklesanlGDsgflvvRegkvvhrskeqqhyFntPyqLsipPeerdgkvisdspeaAdstsfevkkgDiillatDGvfDnlsedqilee LTEMSGiSNPVRLQMAANTVALMARTLSFSPKHDSPFSQNARKHDIDAWGGKPDDITVLLASV |.|... .....||..||..|..||.|||.||..|||.|.|.|....|.|||||||||.||.| lkelke-rdeeelqllanslaekareLsfdpkyespFaqkakkrglaasGGKpDDitvvlavv |
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| Phosphatase | CG15035.AA | Subfamily.PPTC7.PD | 111-373 | 55 | 1.2e-124 | 404.7 | In-house | 2-263 (263) | Show / Hide |
Range on Protein: 111-373 Range on HMM: 2-263/263 Sequence Identity: 55% (145 aa) SVTCGFAKDHIRYPEYNRGKFGEDAWFMSSSPQACIMGVADGVGGWRNYGVDPGKFSMTLMRSCERMSHAPDFKPNRPEILLERAYFDLLDQKCPIVGSC ||.||||||........|.||||||.|.||...|...||||||||||.||.||..||..||..|||......||...|...||.||..||..|.|.|||. svvcgfakdllkqkskkrskfGeDayFvssnkvadvlgVADgvggwreygidpsefskelmkkcerivkeskfkerkpkkileaayqelleekvpvvGss TACILALKRDDSTLYAANIGDSGFLVVRSGKVVCRSQEQQHQFNTPYQLASPPPGYDFDAVSDGPESADTIQFPMQLGDVILLATDGVYDNVPESFLVEV ||||..|.|.|..|..||.|||||||||.||||.||.||||.|||||||. ||...| ....| ||.||...|... ||.||||||||.||..|. ..|| tacivvldredkklesaNlGDSgflVvRngkvvhrskeqqhyFNtPyqLsipPeerdgkvildkpeaadstsfevkkgDlillatDGvfDNlsedeilev LTEMSGiSNPVRLQMAANTVALMARTLSFSPKHDSPFSQNARKHDIDAWGGKPDDITVLLASV |.|... ... .||..||..| .||.||..||..|||...|.|....|.|||||||||.||.| lkelke-rdeeelqllanslaekarelsldpkyespFakkakknglaasGGKpDDitvvlalv |
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| Phosphatase | CG15035.AA | Group.PPM.PD | 131-248 | 18 | 8.2e-14 | 40.5 | In-house | 52-188 (459) | Show / Hide |
Range on Protein: 131-248 Range on HMM: 52-188/459 Sequence Identity: 18% (26 aa) FgEDAWFMSSSPQA--CIMGVADGVGGWRNYGVDPGKFSMTLMRSCERMS------------------HAPDFKPNRPEILLERAYFDLLDQKC--PIVG ||.... .... ...|| || ||.. . |.. |...... . . .. . |.... . ..| .. . . m-EDrhvivenfdnndsffgVfDGHgGaeaaefaakkLpkilkkqlkkkkdevskksaeasldnddrgekvkkalrsafleldedlseeanekeepgkds SCTACILALkRDDsTLYAANIGDSGFLVVRSGKVVCRSQE ||... . ... .|| ||.||| ...|.||.|. |.. GtTAvvali-ngk-klyvANaGDSravLcrngkavplskd |
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| Phosphatase | CG15035.AA | Group.PPM.PD | 279-372 | 18 | 1.3e-08 | 23.3 | In-house | 240-320 (459) | Show / Hide |
Range on Protein: 279-372 Range on HMM: 240-320/459 Sequence Identity: 18% (18 aa) DTIQFPMQLGD-VILLATDGVYDNVPESFLVEVLTEMSGI---SNPVRLQMAANTVALMARTLSfspkhdspfsqnarkhDIdAWGGKPDDITVLLAS |. ..... | .. ||.||..| . . .||.. | . . .. .|...|. .. |. . . .|...|.|||... dvsvvklteedeflvlAsDGlWdvlsneevvefvretlekkkkelkkdleeiaerlvdealakg----------------st-gdgtscDNiTvivvt |
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| Phosphatase | CG15035.AA | Family.PPM.PD | 199-249 | 32 | 2.8e-08 | 22.1 | In-house | 112-161 (495) | Show / Hide |
Range on Protein: 199-249 Range on HMM: 112-161/495 Sequence Identity: 32% (16 aa) LLDQKC-PIVGSCTACILALKRDDstLYAANIGDSGFLVVRSGKVVCRSQEQ |..| . . .||... ..... ||.||.||| ...|.||.|. |.. elneksagkdsGtTAvvvlirgkk--lyvAnaGDsravLcrngkavelskdH |
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| Phosphatase | CG15035.AA | PP2C_SIG | 118-373 | 13 | 1e-06 | 20.61 | SMART | 1-250 (250) | Show / Hide |
Range on Protein: 118-373 Range on HMM: 1-250/250 Sequence Identity: 13% (40 aa) KDHIRYPEYNRGKFG--EDAWFMSSSPQ---ACIMGVADGVGGWRNYGVDPGKFSMTLMRSCERMSHAPDFKPNRPEILLERAYFDLLDQ-KCPIVGSCT ||. .. |. | .. | . .. ..|..| | |. . ... . . ..|. |. .|||. . .. . . .| DDHWDIYQYYEDATQVCGDWYDFWKIPEGQDRYFFVIGDVMG-WA-HGLPAALMMGMARTMMRTFWHE------SPPQILERCNRWIYQNNHEECGMFTT ACILAL--KRDDSTLYAANIGDSGFLVVR--SGKVVCRSQE-------------------QQHQFNTPYQLA---SPPPGYDFDAVSDGPESADTIQFPM .|.. . ..||. ...|.| ....| .|. | . .. .. ..| . | .. .|. .|.. MCCCVYMPDFATHTLWYCHCGHSPPYLYRAMDGGRVEHTHDHYLVQHYVMRIIDEEDAKHHPWHNWTGPPLGMEPDYM--------------YDVQEFQY QLGDVILLATDGVYDNVPESF----------LVEVLTEMSGISNPVRLQMAANTVALMARTLSFSPKHDSPFSQNARKHDIDAWGGKPDDITVLLASV . ||.....|||| ... . ..| .. . ..|. .. . ... ... .||.||.. | EPGDRFVMCTDGVTEARNPQGEFFGEEWLQEILEEHQ------CCCPQEIAQRIMQELMEHMGDHNG--------------------HDDMTVIVVKV |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| CG15035.AA | Protein | None | 374 | None | Fasta, JSON |
| CG15035.NA | RNA | None | 1122 | None | Fasta, JSON |
| CG15035.AA.PD_110-373 | Protein Phosphatase Domain | None | 264 | None | Fasta, JSON |