flw
Species: D.melanogaster
Alias: flw
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: PPP
Family: PPP
Subfamily: PPP1C
Protein domain

Protein domains of flw.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase flw.AA Family.PPP.PD 22-303 55 5.9e-136 443.1 In-house 61-344 (349) Show / Hide
Range on Protein: 22-303
Range on HMM: 61-344/349
Sequence Identity: 55% (157 aa)

RTGKQVQMTEAEVRGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAA-NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL
.. .. |....||  |. . .|.. ..|.|||.|||. .|||||||..||||||. .|.|||  .||||||||||||.|.|.|.||.|.|..||..||||
afkekkqleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsrffll

RGNHECASINRIYGFYDECKRRY--NVKLWKTFTDCFNCLPVAAIIDEKIFCCHGGLSPDLQGMEQIRRLMRPTDVPDTGLLCDLLWSDPDKdVQGWGEN
|||||..|.|..||||.|.|..|  . .....|...||.||.||.|||||.|.||||||.|. ..|||.. ||...|..|||||||||||....|| .|.
RGnhEsrsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdpee-qkgwkpn

DRGVSFTFGVDVVSKFLNRHELDLICRAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGGMMTVDDTLMCSFQILKPSEKKAK
|||.|.|| |.|.|||....||||.|||.|||.|||||| |.|||.|||||||||..|.. ...||..|..|....|||..| . 
kRGvgfvFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskhklr

Phosphatase flw.AA Subfamily.PPP1C.PD 29-298 85 2.1e-171 558.4 In-house 1-270 (271) Show / Hide
Range on Protein: 29-298
Range on HMM: 1-270/271
Sequence Identity: 85% (231 aa)

MTEAEVRGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECAS
..|||.| ||||.|||||.||||||||||| |.|||||||.|||||||.|||||..|||||||||||||||||||.||||||||||||||||||||||||
lkeaeirklclkareiflsqpilleleaplkivGdihGqyadllrlfekggfppesnylflGdyvdrGkqsletivlllaykikypenffllrGnhecas

INRIYGFYDECKRRYNVKLWKTFTDCFNCLPVAAIIDEKIFCCHGGLSPDLQGMEQIRRLMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGV
||||||||||||||||.||||||.|||||||||||.||||||.||||||||. .|||||..|||||||.|||||||||||||.|.|||||||||||||| 
inriygfydeckrryniklwktfvdcfnclpvaaivdekifcvhGGlspdlksleqirriarptdvpdkGllcdllwsdpdkevkgwgendrgvsftfga

DVVSKFLNRHELDLICRAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGGMMTVDDTLMCSFQILKPS
|||.|||..|.||||.||||||||||||||.||||||||||||||||||||..|.||..|.||||||||.
dvvekflkkhdldlivrahqvvedgyeffakrqlvtlfsapnycgefdnagavmsvdeellcsfqilkpa

Phosphatase flw.AA PP2Ac 29-299 47 4.3e-163 549.02 SMART 1-321 (321) Show / Hide
Range on Protein: 29-299
Range on HMM: 1-321/321
Sequence Identity: 47% (153 aa)

MTEAEVRGLCLKSREIFLQQPILLELE----APLIICGDIHGQYTDLLRLF---EYGG-FPPAANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL
|.. |.. || ...||| |.| ..|.|    .|  .|||||||. ||||||   . .| .||  ||.|||||||||..|.|.||||..|||.||.|||||
MHKHEIYQLCHEVKEIFRQEPNMVEVEETPTPPVTVCGDIHGQFDDLLRLFKKEDKNGKPPPYTNYVFLGDYVDRGPWSIECICLLFCYKICYPNNFFLL

RGNHECASIN---RIYGFYDECKRRY-NVKLWKTFTDCFNCLPVAAIIDEKIFCCHGGLSP------DLQGMEQIRRLMR----PTDVPDTGLLCDLLWS
|||||| ..|   ..|||||||||.| ....|| |..||...|..|.|. ||.| ||||||      ...  ..||.. |    | . || ||.||||||
RGNHECRHMNMWVQYYGFYDECKRKYYHKRIWKIFQECFSWMPLCALINNKILCMHGGLSPRECQTDHIHTLDDIRNIDRPQHPPQEPPDWGLMCDLLWS

DP--------DKDVQGWGEND-RGVSFTFGVDVVSKFLNRHELDLICRAHQVVE----DGYEFFARR-----QLVTLFSAPNYCGEFDNAGGMMTV----
||        |..|.||. |  ||.|..|| |||..|.... ||||.||||.|.    |||||...|     .|.|.|||||||...||.. .| |    
DPVDFQWFHDDQWVPGWQPNCMRGMSYYFGPDVVDEFCKKNNLDLIIRAHQCVQYQMMDGYEFWHDRDTRVHKLITIFSAPNYCDQCDNHAAVMKVNDHK

------DDTLMCSFQILKPSE
      |. |.|.|. .|| .
VIQYKMDKNLKCHFVQFKPQM

Phosphatase flw.AA Group.PPP.PD 22-303 55 5.9e-136 443.1 In-house 61-344 (349) Show / Hide
Range on Protein: 22-303
Range on HMM: 61-344/349
Sequence Identity: 55% (157 aa)

RTGKQVQMTEAEVRGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAA-NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL
.. .. |....||  |. . .|.. ..|.|||.|||. .|||||||..||||||. .|.|||  .||||||||||||.|.|.|.||.|.|..||..||||
afkekkqleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsrffll

RGNHECASINRIYGFYDECKRRY--NVKLWKTFTDCFNCLPVAAIIDEKIFCCHGGLSPDLQGMEQIRRLMRPTDVPDTGLLCDLLWSDPDKdVQGWGEN
|||||..|.|..||||.|.|..|  . .....|...||.||.||.|||||.|.||||||.|. ..|||.. ||...|..|||||||||||.. ..|| .|
RGnhEsrsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdpee-qkgwkpn

DRGVSFTFGVDVVSKFLNRHELDLICRAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGGMMTVDDTLMCSFQILKPSEKKAK
.|||.|.|| |.|.|||....||||.|||.|||.|||||| |.|||.|||||||||..|.. ...||..|..|....|||..| .
kRGvgfvFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskhklr

Phosphatase flw.AA Subfamily.PPP_Nematode_6.PD 30-298 59 2.1e-133 433.5 In-house 2-271 (272) Show / Hide
Range on Protein: 30-298
Range on HMM: 2-271/272
Sequence Identity: 59% (160 aa)

TEAEVRGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASI
.|.|.  |. .....| .|. |.|.|||. .||||||||.||||||. ||||| |||||||||||||.||||.|.||||||.|.|.|||||||||||..|
keeellkllelakkvfkkqkslveveapikvcGdihGqysdllrlfdkggfppdanylflGdyvdrGrqslevillllaykvkfpnnffllrGnheceai

NRIYGFYDECKRRYN-VKLWKTFTDCFNCLPVAAIIDEKIFCCHGGLSPDLQGMEQIRRLMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGV
||.||||||..|||. ..|...| ..|| ||..|.. ..|.| |||||. |. ..|.|.| ||.| ... |  |||||||.. |.|| || |||| .|| 
nrvyGfydevqrrykstrlyaafqevfnalpltalvsgrilcmhGGlskklksldqlrelkrpldskeeslaidllwsdpenavkgwaensrGvsvvfGe

DVVSKFLNRHELDLICRAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGGMMTVDDTLMCSFQILKPS
|.| |.|.. ..||..||||||.||||||| ..|||.||||.|||.|||| ..|.||. |..||..|||.
davkkllekldidlvarahqvvqdGyeffaekklvtifsaphycgqfdnaaavmkvdeklvvsfevlkpe

Phosphatase flw.AA Subfamily.PPP4C.PD 30-296 48 9.60000000001e-103 333.0 In-house 2-268 (271) Show / Hide
Range on Protein: 30-296
Range on HMM: 2-268/271
Sequence Identity: 48% (129 aa)

TEAEVRGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASI
.| ||. || |.|||....  . ....| ..|||||||. |||.||. ||  |  |||||||.||||. |.||. ||||.|..||..  |.|||||. .|
keeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesrqi

NRIYGFYDECKRRY-NVKLWKTFTDCFNCLPVAAIIDEKIFCCHGGLSPDLQGMEQIRRLMRPTDVPDTGLLCDLLWSDPDkDVQGWGENDRGVSFTFGV
 ..||||||| |.| ....|.  |. |. |..|||||.|||| ||||||... ...|| . | ..||. | |||||||||.|..||.   ||  . || |
tqvygfydeclrkygsaevwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpe-daegwavsprgagylfgs

DVVSKFLNRHELDLICRAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGGMMTVDDTLMCSFQILK
||..| .. ...|||||||.| .||..  .....|..||||||    |   .. .|..|   |.|.. 
dvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkife

Phosphatase flw.AA Subfamily.PPP_Nematode_4.PD 29-297 47 4.8e-102 330.8 In-house 1-269 (271) Show / Hide
Range on Protein: 29-297
Range on HMM: 1-269/271
Sequence Identity: 47% (126 aa)

MTEAEVRGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECAS
.|. |.  .  ....|| ..  | |.|||. . ||.|.|. || |||.  | .|   ..|||||||||.|..|.. ||...||.|... .||||||| ||
ltkeeiisvireaeaifsdekalveieapikvvgdlhaqfqdlirlfdllgrvpeeklvflgdyvdrgpqgievlillfclkiryrdrivllrgnheias

INRIYGFYDECKRRYNVKLWKTFTDCFNCLPVAAIIDEKIFCCHGGLSPDLQGMEQIRRLMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGV
.|..||||.||. .| ..|| .|  ||| ||..|.| .|..| ||||||.|  ....|   .|. .| ||| ||||.|||..|..| .  ||.|.||| .
vnkkygfyeecvtkygeelwadfqrcfnrlpisaliakkvlcmhgglspelisldelrnipkpienldrgllidllwadpdnkveewkasirgisytfgk

DVVSKFLNRHELDLICRAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGGMMTVDDTLMCSFQILKP
|| .   . |.||| |||||| |||| .. |.|.|.||.||||| ||. ....|..|  |.. | |   
gvvedvckslevdliirahqvvqdgyevlsgrklitvfsvpnycaqfknaaavlkldenleislvalvp

Phosphatase flw.AA Subfamily.PPP2C.PD 30-298 49 6.6e-98 317.2 In-house 2-270 (271) Show / Hide
Range on Protein: 30-298
Range on HMM: 2-270/271
Sequence Identity: 49% (133 aa)

TEAEVRGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASI
.|.||. || |..||. ..  . |...|. .|||.|||. ||| ||  ||  | .||||.|||||||  |.||..||.| |..|.|   .||||||   |
eeeevkklcekakeilskesnvkevkcpvtvcgdvhgqfhdllelfriggkspdtnylfmgdyvdrgyysvetvtllvalkvrykeritilrgnhesrqi

NRIYGFYDECKRRY-NVKLWKTFTDCFNCLPVAAIIDEKIFCCHGGLSPDLQGMEQIRRLMRPTDVPDTGLLCDLLWSDPDkDVQGWGENDRGVSFTFGV
 ..||||||| |.| | ..|| ||| |..||..|..|..||| |||||| .. ...|| | |  .||  | .|||||||||| .|||   ||  .||| |
tqvygfydeclrkygnanvwkyftdlfdylpltalvdnqifclhgglspsidtldkiraldrlqevphegpmcdllwsdpd-drggwgisprgagytfgk

DVVSKFLNRHELDLICRAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGGMMTVDDTLMCSFQILKPS
.  .| .. .| |..||||.| .||..   |..||.|||||||    | .... .||.|  ||   .|. 
diseefnktngltlvsrahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddelkysflqfdpa

Phosphatase flw.AA Subfamily.PPP_Nematode_3.PD 84-298 52 7.3e-97 314.1 In-house 93-307 (308) Show / Hide
Range on Protein: 84-298
Range on HMM: 93-307/308
Sequence Identity: 52% (112 aa)

ANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDCFNCLPVAAIIDEKIFCCHGGLSPDLQGME
.|||||||||||  |.| . ||.|.|..||.. ||||||||  ..|. |||| |.|.||...|...|   ||.||..|....||.| |||.| .|  ..|
kkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysaalyeafqlafnvlplcavvnkkilcmhGGiseelldlk

QIRRLMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGVDVVSKFLNRHELDLICRAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGGMMT
. .| ||.|.|| |.|.|| |.|||..|.|. |  || .. || . | .||....|||. |||||||||||||| |.|||.||||.|||..||.. ...|
qldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavls

VDDTLMCSFQILKPS
|. |..|...|.|. 
vdkklvisltvlrpe

Phosphatase flw.AA Subfamily.PPP_Nematode_5.PD 40-298 46 1.1e-93 303.0 In-house 12-273 (274) Show / Hide
Range on Protein: 40-298
Range on HMM: 12-273/274
Sequence Identity: 46% (121 aa)

KSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDEC
| ...    . |||.|||. |.||||||. ||||.|.  | .|  .||||||||||| .||| . ||...||.||..  |||||||.  ||..|||..| 
kikstlkplaalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrgnhevkkinklygfkeel

KRRYNVKLWKTFTDCFNCLPVAAIIDEKIFCCHGGLSPDLQGMEQIRRLMRPTDVPDT--GLLCDLLWSDPDKDVQGWGEND-RGVSFTFGVDVVSKFLN
|.... .|.|.| | |. ||. |.....|.| |||.||.|. ..... | .||   .   ||||||.||.|| ..   |  |..|  ||  .| ..|.. 
kkkrqeslykkfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkiraisvvfGkkevddllk

RHELDLICRAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGGMMTVDDTLMCSFQILKPS
..||| |||.|.|.||.|.. ..|||.|||| |.||  | | ...|...|  ||  |||   
kldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkpe

Phosphatase flw.AA Subfamily.PPP6C.PD 30-293 44 3.7e-92 298.2 In-house 2-265 (271) Show / Hide
Range on Protein: 30-293
Range on HMM: 2-265/271
Sequence Identity: 44% (119 aa)

TEAEVRGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASI
.|.|.. || .  ...|..  .  ...|. .|||||||. ||. ||  ||  | ..|.||||.||||  ||||. .||. |.|||..  |||||||.  |
penelkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesrqi

NRIYGFYDECKRRY-NVKLWKTFTDCFNCLPVAAIIDEKIFCCHGGLSPDLQGMEQIRRLMRPTDVPDTGLLCDLLWSDPdKDVQGWGENDRGVSFTFGV
 ..|||||||...| |.. || .|. |. |..||||||...| |||||||.. ..||| . | ...|  | .|||.|||| .||. |   .||  . || 
tqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhgglspdvktldqirvieraqeiphkgafcdlvwsdp-edvetwavsprgagylfgs

DVVSKFLNRHELDLICRAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGGMMTVDDTLMCSFQ
 |...|..  .|.|||||||.||.|....   .|||..||||||    |   .....|.   ...
kvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgniasilaledaeereak

Phosphatase flw.AA Subfamily.PPP_Nematode_2.PD 32-291 45 9.2e-86 277.1 In-house 4-273 (281) Show / Hide
Range on Protein: 32-291
Range on HMM: 4-273/281
Sequence Identity: 45% (119 aa)

AEVRGLCLKSREIFLQQPILLELEA---PLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECAS
|.| ..  ... ||... ||...    |. . .|.|||..||||.|   . |.  .|||||||||||.||.|...||||||.||.  ||||||||     
eeiriisnyakkaflefsallrvdeeclpvtvvadlhgqsidllriflineapgiskylflgdyvdrgrqsvevvllllaykhlypdhlfllrgnhedvn

INRIYGFYDECKRRYNV---KLWKTFTDCFNCLPVAAIIDEKIFCCHGGLSPDLQGMEQIRRLMRPTDVPDTGLLCDLLWSDPDKD-VQGWGENDRGVSF
  |||.|||. .||    | |. . |.||.||.||.| .|..| |||.|| |. .|.| ..||. ||  || ||||||||.|   .||.   ||.||.|.
ttltygffdeclekyndkgekvwlmiidafnhlplaalildkvlcahggisphlekledidkierplvvpsyglacdllwsdpektervgwslsargisf

TFGVDVVSKFLNRHELDLICRAHQVVE----DGYEFFARRQLVTLFSAPNYCGEfDNAGGMMTVDDTLMCS
  || || .  .|||. ||||...    .|. . |  .||.|||| || .  .|   .. ..         
sfddivvekfcadndldlvvrahqlskemirqghklrangrlvslfsalnylsm-kndssvlkleevktlq

Phosphatase flw.AA Subfamily.PPP3C.PD 31-289 40 2.2e-85 276.3 In-house 3-274 (292) Show / Hide
Range on Protein: 31-289
Range on HMM: 3-274/292
Sequence Identity: 40% (106 aa)

EAEVRGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASIN
|...  .  .. ... ... |||.|||....||||||. |||.||| || | ...|||||||||||  |.|..  |.| ||.||...|||||||||  . 
eesalkiieeaakllkkeetlleveapitviGdihGqfydllklfevgGkpastkylflGdyvdrGyfsiecvlylyalkiaypsrlfllrGnhecrhlt

RIYGFYDECKRRYNVKLWKTFTDCFNCLPVAAIIDEKIFCCHGGLSPDLQGMEQIRRLMRPTDVPDTGLLCDLLWSDPDKDV------QGWGEN-DRGVS
  . | .|.| .|. .........|..||.||....| .|.||||||... ...|..| |  ..| .| ||||||||| .|. . .|  || |. ..   
eyftfkeevkikyseevyealmesfdslplaallnqkflcvhGGlspeikslddikkldrfkeppasGplcdllwsdpledygeeetseeflpnsvrGcs

FTFGVDVVSKFLNRHELDLICRAHQVVEDGYEFFAR------RQLVTLFSAPNYCGEFDNAGGMMTVDDTLM
|..||.. .|  | |||.. ..||. . .        |.||||||||.. ..| . .. ...  .       
yfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfpslitlfsapnyldvynnkaavlkyennvl

Phosphatase flw.AA Subfamily.PPP5C.PD 32-291 44 3.9e-82 265.8 In-house 73-338 (346) Show / Hide
Range on Protein: 32-291
Range on HMM: 73-338/346
Sequence Identity: 44% (116 aa)

AEVRGLCLKSREIFLQQPILLELEAP----LIICGDIHGQYTDLLRLFEYGGFPPAA-NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHEC
.  . |.. |.. ..| |.|.. |    . .|||||||. ||| .||  | |     ||| ||.||||  |.|.| .||..|. ||..||| |||||  .
kyalkilleakellkklpslveitipetkkitvCgdihgqfyDllnifelnGlpseenpylfngDfvdrGsfsveviltllgfkllypnhfflsrGnhes

ASINRIYGFYDECKRRYNVKLWKTFTDCFNCLPVAAIIDEKIFCCHGGL-SPDLQGMEQIRRLMRPTDVPDTGLLCDLLWSDPDKdVQGWGENDRGVSFT
.|..||| .|.| .|. |. . ||. || ||.| .|.||.. .|||| | |   ....|.. | .. |. |||..||||||..  .| ..  |||...||
dnmnklyGfegevkakytekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeeglllellwsdpqe-anGrspskrGvgiq

FGVDVVSKFLNRHELDLICRAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGGMMTV-DDTLMCS
 || .|||.  .|.|| |.|.| |.|||.    .|.|.||||||| . .| |...|. .| |     
fGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlkpk

Phosphatase flw.AA Subfamily.PPP_Nematode_7.PD 31-296 36 2e-69 223.8 In-house 3-293 (296) Show / Hide
Range on Protein: 31-296
Range on HMM: 3-293/296
Sequence Identity: 36% (106 aa)

EAEVRGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLF----------EYGGFP-PAANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
. |.  |. .  | | .. .|.|. .|..| |||||||.|| |.           .  ...     ..|||||||||..|.||.|..|.|| ||....||
knellslidavkelfkkektlaeispPvtivGdihGqyeDLvriLnarvskeeakqksalsfvrkkfvfLGdYvdrGsksieCisLvfalkilyptkyil

LRGNHECASINRIYGFYDECKRR----YNVKLWKTFTDCFNCLPVAAIIDEKIFCCHGGLSPDLQGMEQIRRLMRPT-DVPDTGLLCDLLWSDP------
|||||. .||  |.|  | . |       .... | ..|  .|.||.. |||.| |||.|| |. .|.|... ||  .| .  |  |||..||       
lrGnhetkainfayefreelenrlskidgkeiyekfnevfsfmplaalvgekilcvhggispklesledinsierPlaevtedslakdllfadpldvqll

--DKDVQGWGEN-DRGVSFTFGVDVVSKFLNRHELDLICRAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGGMMTVDDTLMCSFQILK
  ..   . .|  ||.|..|.   |... .. .|.|| |||| .|..||| ..|.|.||||.| .|.|| | .. |.     | ..|.   
aavsekpkyeknevrglsvvfneaavedvCrklnlklivrahqkipegfkffadkkLltifsaprymnesdnsgavlkveangklsiaslr

Phosphatase flw.AA Metallophos 56-251 28 1.1e-44 159.51 Pfam 1-124 (124) Show / Hide
Range on Protein: 56-251
Range on HMM: 1-124/124
Sequence Identity: 28% (56 aa)

APLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDCF
.....|||||||| ||.|||| .   .. ...|.|||||||..|.|.|.||..||..|| .....||||.....|. |||| |       ..| .. ..|
MRILHCGDIHGQYDDLNRLFEII-E-KPDFVIFTGDYVDRGPWSDECIWLLFCYKMNYPGPVYWVRGNHDYMHGNDFYGFY-E-------NDW-MWWWWF

NCLPVAAIIDEKIFCCHGGLSPDLQGMEQIRRLMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGVDVVSKFLNRHELDLICRAHQVVE
 ..| | ..| ||.|.||..                                                          |.  ...|...|.|. |.
-WMPLA-LDDWKILCMHGPP----------------------------------------------------------FCK-NGVDYVIRGHTHVP

Phosphatase flw.AA Subfamily.PPP_Nematode_1.PD 47-296 27 3.9e-39 124.5 In-house 18-268 (273) Show / Hide
Range on Protein: 47-296
Range on HMM: 18-268/273
Sequence Identity: 27% (69 aa)

QQPILLE-LEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECK-RRYN
... ||| .||.. ..||| ..|.|||....  |.|.   .||||. .| || |||.. .||  |. ||.|...|||..|.     .. | . |  . . 
eetslleyieadvtviGdirsryadlldilkltGwPfeqkilflGnlldsGkssleellillcskkcyPknvvilrGeyetelvksdrrligelrvrfpd

VKLWKTFTDCFN----CLPVAAIIDEKIFCCHGGLSPDLQGMEQIRRLMRPTDVPDTGLLCDLLWSDPDKDVqGWGENDrgvsfTFGV-DVVSKFLNRHE
|..   .       |||||... |... ..|.|. ..  ...  . |     .     ... | |.      |||      ..   .| . |   .....
snkwralnaiikrllkrlPvaavlnkkllavysgvssnikekknvvavkrgiifenhstrvevqfldidiPs-Pvtend-----idekskivkellkatd

LDLICRAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGGMMTVDDTLMCSFQILK
 |...|| .|| |  . .|.||.||...  ...| | ....||  .|. ..      
msvmirsnsvvreGylftlknrlitltsatklqkdynnrGvvlsidkdlkvtfklie

Phosphatase flw.AA Subfamily.PPP7C.PD 58-187 42 1.1e-38 122.7 In-house 70-205 (338) Show / Hide
Range on Protein: 58-187
Range on HMM: 70-205/338
Sequence Identity: 42% (57 aa)

LIICGDIHGQYTDLLRLFEYGGFPPAA-NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY---NVKLWKTFTD
. .|||.||.  ||| ..   |.| |  .|.| ||.|||||.|.| ...|.|. . ||....| |||||   .|  |||  | . .|   .|. ... | 
vtvcgdlhgklddlllilyknGlpsaenpyvfnGdfvdrGkesveillilfalllvypkevylnrGnhedyilnlryGfikeveskykvhgkkilrlled

CFNCLPVAAIIDEKIFCCHGGLSP--DLQGMEQIRR
|  ||.|..|||||. .|||.|   ||. ...| | 
vfawlplatlidekilivhGGisdktdlelldkier

Phosphatase flw.AA Subfamily.PPP7C.PD 200-289 35 1.1e-20 63.5 In-house 239-328 (338) Show / Hide
Range on Protein: 200-289
Range on HMM: 239-328/338
Sequence Identity: 35% (32 aa)

LCDLLWSDPDKDVQGWGENDRGVSFTFGVDVVSKFLNRHELDLICRAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGGMMTVDDTLM
. |.||||| ..   . .  ||    || || .|.|....|.|. |.|.   .||||   ....|.||| ||  |  | |  . . ..|.
ildilwsdpkaqeGckpntlrGgGsyfGpdvtkkllqkynlellirsheckpeGyefthnkkvltifsasnyyeeGsnrGayvklgkdlt

Phosphatase flw.AA Subfamily.PPP_Nematode_3.PD 30-82 51 1.5e-17 53.6 In-house 2-54 (308) Show / Hide
Range on Protein: 30-82
Range on HMM: 2-54/308
Sequence Identity: 51% (27 aa)

TEAEVRGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPP
.|.|.  ||...||.| ..|. ||||||. |.||||||. ||| |..  |.| 
kekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnGwpl

Sequence
Name Sequence Type Origin Length Description Download
flw.AA Protein None 330 None Fasta, JSON
flw.NA RNA None 990 None Fasta, JSON
flw.AA.PD_29-299 Protein Phosphatase Domain None 271 None Fasta, JSON