• Phosphatome.Net

Gene mbre_CDC14

mbre_CDC14
Species: M.brevicollis
Alias: mbre_CDC14
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: CDC14
Protein domain

Protein domains of mbre_CDC14.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase mbre_CDC14.AA Subfamily.CDC14.PD 314-571 86 3.8e-168 549.1 In-house 1-258 (258) Show / Hide 
Range on Protein: 314-571
Range on HMM: 1-258/258
Sequence Identity: 86% (223 aa)

QPQHKDQRIYFCTGTDMQVRSNAAALIGLFAVWCLNMTDEQAIACLDTAKPPFAPFRDASYAPVLYKLHVRYVISGAYQALLNGFIDVHTFDLDTYDHFE
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
qpqhkdqriyfctgtdmqvrsnaaaliglfavwclnmtdeqaiacldtakppfapfrdasyapvlyklhvryvisgayqallngfidvhtfdldtydhfe

RVENGDFTTIIPNKFIALAGPHNTRHVDDGYTHLAPENLFEPFRRLGVTDIVRLNKKMYDRTKFTQAGFAHHDLFFIDGTCPPPAILESFLEITEKCTGT
|||||||||||||||||||||||...|.||||.||||.|.|.||...||.|||||||.||..|||.|||||.||||||||.|..|||..|||||||..|.
rvengdfttiipnkfialagphnkskvedGytllaPeklleyfrknnvttivrLnkklYdakkftdaGfahlDlffiDGtvPsdailkkfleitekaeGa

AVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARPGSVIGPQQTYLVNHQADM
..|||||||||||.|||||..|||||.|.|||||||||||||||||||||||..|||.
iavhCkaGLGrtgtligcylikhyrftaaetiawlriarPGsvigpqqtylvekqadl
Phosphatase mbre_CDC14.AA Family.DSP.PD 314-576 54 4.8e-109 356.7 In-house 1-249 (387) Show / Hide 
Range on Protein: 314-576
Range on HMM: 1-249/387
Sequence Identity: 54% (147 aa)

QPQHKDQRIYFCTGTDMQVRSNAAALIGLFAVWCLNMTDEQAIACLDTAKPPFAPFRDASYAPVLYKLHVRYVISGAYQALLNGFIDVHTFDLDTYDHFE
||||||||||||||||||||||||||||||||||||||||||||||||.||.|||||||||||||.|||||||||||.||.|||||||||||||||||||
qpqhkdqriyfctGtdmqvrsnaaaliGlfavwclnmtdeqaiacldtvkpkfapfrdasyapvlaklhvryvisgakqaelngfidvhtfdldtydhfe

RVENGDFTTIIPnkfialagphntrHVDDGYTHLApeNLFEPFRRLGVTDIVRLNkkmYDRTKFTQ-AGFAHHDLFFIDGTCPPPAI-LESFLEITEK--
|||||....|.|             |...|... |  . .|....||||.||.|.   .|...||. .|.........|...||... .|......|.  
rvengkpseilp-------------hlylgsllaa--knlewlkelgvtkivnlt---ddkpqftkelgikylripidDhnapplenlfekaidfieegn

-CTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARPgSVIGPQQTYLVNHQADMWLASP
 ..|...||||||.||.|.|| .|.||.......|...|.|..|| .|| |.|..|..... .   ..
dskgvVlVHCkaGkgRsgtliiaYlmksegltleealdwvrskRp-gvitpnqgflkqlkdlekeklk
Phosphatase mbre_CDC14.AA Subfamily.PTPDC1.PD 472-567 34 3.9e-15 47.4 In-house 125-222 (229) Show / Hide 
Range on Protein: 472-567
Range on HMM: 125-222/229
Sequence Identity: 34% (33 aa)

YDRTKFTQAGFAHHDLFFID-GTCPPPAILESFLEITEKCT-GTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARPGSVIGPQQTYLVNH
||  .. ..| ...   . | |...   ||.    ..  .. |   ||| |||||||.|| ||.. . |..| | |  .|  || |..|  ||..   
YdpeelmrqgiyfynfglkDygvasleriLdivkvvdfaleegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrpksiqtreqvelvee
Phosphatase mbre_CDC14.AA Subfamily.PRL.PD 454-569 28 5.7e-15 46.9 In-house 19-138 (140) Show / Hide 
Range on Protein: 454-569
Range on HMM: 19-138/140
Sequence Identity: 28% (34 aa)

EPFRRLGVTDIVRLNKKMYDRTKFTQAGFAHHDLFFIDGTCPPPAILESFLEIT-----EKCTGTAVVHCKAGLGRTGSLIGCYMMKHyRFNAPETIAWL
| ...  |...||  .  || .|. ..|   .|| | ||. || ......||.      |.   |  ||| |||||.  |.   .. .  ..... ..| 
eelkkenvkevvrvcepsydaeklkeegievldlafddGavPpkevvdeWlellkekfkeepkstvavhcvaGlGraPvlvalaliea-Gmkyedavefi

RIARPGSVIGPQQTYLVNHQA
 | |..   | ..| ...|  
rekrrgainskqlkflekyka
Phosphatase mbre_CDC14.AA Subfamily.DSP23.PD 460-565 29 8.5e-15 46.5 In-house 13-120 (128) Show / Hide 
Range on Protein: 460-565
Range on HMM: 13-120/128
Sequence Identity: 29% (32 aa)

GVTDIVRLNKKMYDRTKFTQaGFAHHDLfFIDGTCPPPA-ILESFLEITE---KCTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARPGS
|.  .| | ..    .. .. . . . .  |.  |||    .. ...| |   |  ..  |||  ||||||.|. ||..|. .. | ..||.|  |.||.
Girvlvslttegapyseaap-sltlrri-dipdfcPPaleqvarlvriveeaekkeeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrrkGs

VIGPQQTYLV
   .|  .| 
ietveqekav
Phosphatase mbre_CDC14.AA Subfamily.PTPMT1.PD 471-561 30 5.9e-11 33.9 In-house 42-136 (146) Show / Hide 
Range on Protein: 471-561
Range on HMM: 42-136/146
Sequence Identity: 30% (28 aa)

MYDRTKFTQAGFAHHDLFFIDGTC-PPPAILESFLEITEKCT--GT-AVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARPGSVIGPQQ
.    .... |  .  |  .| |  |  . ||  .|. || .  |    |||||| .| ..|..||.||...... | .  |.  ||.  .|   
ansteewkklGveqlqlatvDfteapslekleegvefiekvaskgssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpqirlkskq
Phosphatase mbre_CDC14.AA Subfamily.PTEN.PD 511-553 37 1.3e-10 32.6 In-house 94-137 (305) Show / Hide 
Range on Protein: 511-553
Range on HMM: 94-137/305
Sequence Identity: 37% (16 aa)

TGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAP-ETIAWLRIARP
.  ..|||||| |||| .| .|..|.  .. . |..|.   .| 
snVvavHCkaGkGRtGvmicayLlksgikksadealaiydekRt
Phosphatase mbre_CDC14.AA DSPc 516-554 28 4.1e-09 33.61 Pfam 90-134 (151) Show / Hide 
Range on Protein: 516-554
Range on HMM: 90-134/151
Sequence Identity: 28% (13 aa)

VHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWL-----RIAR-PG
|||.||. |...|. .|.|| ......| .. .     .  | |.
VHCQAGISRSACLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPM
Phosphatase mbre_CDC14.AA Subfamily.RNGTT.PD 468-555 23 1e-08 26.5 In-house 30-123 (140) Show / Hide 
Range on Protein: 468-555
Range on HMM: 30-123/140
Sequence Identity: 23% (21 aa)

NKKMYDRTKFTQAGFAHHDLFF-IDGTCPPPAILESFLEITEK-----CTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARPGS
.. ||. .... |  .. |     | .| .   ..|... ..      . .  |||  |  ||| || .|....  ..  . .| .  |||   
tsryydkeelekegvkyiklqcrGrGeaPtkeqtklfiklvkeflkkkPdevigvhCthGfnrtGflivayLvekedwsveaavalfakarppG
Phosphatase mbre_CDC14.AA Subfamily.DSP14.PD 507-559 36 5.5e-08 24.5 In-house 74-124 (138) Show / Hide 
Range on Protein: 507-559
Range on HMM: 74-124/138
Sequence Identity: 36% (19 aa)

TEKCTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARPgsVIGP
.|  | ..|||.||  |  ||.  |.||. . .  |.  ... |||  .| | 
vkkkgGktlvhCvaGvsRsAslvlaylmkyeklsLreayklvksaRp--iirP
Phosphatase mbre_CDC14.AA Subfamily.Slingshot.PD 503-564 30 6.3e-08 24.1 In-house 71-130 (139) Show / Hide 
Range on Protein: 503-564
Range on HMM: 71-130/139
Sequence Identity: 30% (19 aa)

FLEITEKCTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARpgSVIGPQQTYL
|.| . .    ..|||| |. |. | .  | ||.|...  |......  |  |.| | ...|
fiekakekgskvlvhckmGvsrsastviayamkeyelsleealeyvkerr--siikpnkgfl
Phosphatase mbre_CDC14.AA Subfamily.DSP11.PD 468-552 21 7.7e-08 23.8 In-house 31-122 (141) Show / Hide 
Range on Protein: 468-552
Range on HMM: 31-122/141
Sequence Identity: 21% (20 aa)

NKKMYDRTKFTQAGFAHHDLFFIDGTCPPPAILESFLEITEKC-------TGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIAR
.. |.....|. |  .. |.    . |   ....| |  ..             |||  |. ||| ||  |....  ... . |  .  || 
tdryykkkeltdegvkykklncpGhevpekedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyspedaieafeear
Phosphatase mbre_CDC14.AA Subfamily.DSP19.PD 502-554 33 1.6e-07 22.8 In-house 70-122 (139) Show / Hide 
Range on Protein: 502-554
Range on HMM: 70-122/139
Sequence Identity: 33% (17 aa)

SFLEITEKCTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARPG
|.| . .  |. .|||.||  |. |..  |.||. . .  ...  .| |||  
dFieearskdgrvlvHCnAGvSRsasvviaylmkdeelslekalekvrearpc
Phosphatase mbre_CDC14.AA Subfamily.DSP1.PD 502-563 27 2.1e-07 22.6 In-house 70-129 (139) Show / Hide 
Range on Protein: 502-563
Range on HMM: 70-129/139
Sequence Identity: 27% (17 aa)

SFLEITEKCTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARpgSVIGPQQTY
|..  .|. |  .|||.||. |. ...  |.||. ...  |   ...  |  |.| |  .. 
dfidsvkkkgGrvlvhCqaGisrsativlayLmkekkvrleeafefvkqrr--siisPnfgf
Phosphatase mbre_CDC14.AA Subfamily.DSP10.PD 503-560 31 2.9e-07 22.0 In-house 73-128 (141) Show / Hide 
Range on Protein: 503-560
Range on HMM: 73-128/141
Sequence Identity: 31% (18 aa)

FLEITEKCTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARPgsVIGPQ
|.|   |. .. .|||.||. |.  ..  |.||| .    |.  ... .||  .| | 
fieearkrgsrvlvhchaGisrsatvviayvmkhlslslseaykfvkekrP--iisPn
Phosphatase mbre_CDC14.AA Subfamily.R_Nematode_2.PD 502-566 29 4.2e-07 21.0 In-house 184-253 (261) Show / Hide 
Range on Protein: 502-566
Range on HMM: 184-253/261
Sequence Identity: 29% (20 aa)

SFLEITEKCTGTAVVHCKAGLGRTGSLIGCY-----MMKHYRFNAPETIAWLRIARPGSVIGPQQTYLVN
||.. | .   |||| ||.|||...||       ....   .  |... ||  |. ..   .| | ..  
eLlelvkksekPivvhCsaGiGRtmafigteylareveadptieltealkelrehRwkgiqtesqlywlt
Phosphatase mbre_CDC14.AA Subfamily.DSP12.PD 503-553 23 4.2e-07 21.7 In-house 73-123 (143) Show / Hide 
Range on Protein: 503-553
Range on HMM: 73-123/143
Sequence Identity: 23% (12 aa)

FLEITEKCTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARP
|.| . .  |. .|||.||. |  ...  |.||.....  . .  .. ...
FieeglekegavlvHClagvSRSvtiviAYlmkkeklslekAlklvkekkk
Phosphatase mbre_CDC14.AA Subfamily.DSP8.PD 502-553 26 9.5e-07 20.4 In-house 72-123 (143) Show / Hide 
Range on Protein: 502-553
Range on HMM: 72-123/143
Sequence Identity: 26% (14 aa)

SFLEITEKCTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARP
.|.. ...  |. .||| ||  |. ... .|.||. ...  |.  ...  ||
efidkarsangkvlvhclaGisrsatvaiayimktlemsldeayrfvkekrp
Phosphatase mbre_CDC14.AA Subfamily.R_Nematode_3.PD 502-561 22 1.3e-06 19.5 In-house 189-254 (267) Show / Hide 
Range on Protein: 502-561
Range on HMM: 189-254/267
Sequence Identity: 22% (15 aa)

SFLEITEKCTGTAVVHCKAGLGRTGSLI----GCYMMKHYR--FNAPETIAWLRIARPGSVIGPQQ
. ... ||.. ..||||..| .|...|     |. .. . .  ..  . |  ||  |.| .  ...
elikfveksktpvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtele
Phosphatase mbre_CDC14.AA Subfamily.N13.PD 510-569 31 2.9e-06 18.5 In-house 190-253 (259) Show / Hide 
Range on Protein: 510-569
Range on HMM: 190-253/259
Sequence Identity: 31% (20 aa)

CTGTAVVHCKAGLGRTGSLIGCYM-----MKHYRFNAPETIAWLRIARPgSVIGPQQTYLVNHQA
.|  |||| ||.||.|.||  ..      ..  |.  |..  ||  |  .|.  .. |.  ..| 
dagPivvhcsaGiGrsGvlitidvvlglierdkefdvkeivrklreqrq-gvvqtkdqyifvyka
Phosphatase mbre_CDC14.AA Subfamily.N_Nematode_1.PD 503-534 42 6.8e-06 17.1 In-house 188-220 (265) Show / Hide 
Range on Protein: 503-534
Range on HMM: 188-220/265
Sequence Identity: 42% (14 aa)

FLEITEKCTGTAVVHCKAGLGRTGSLIGC-YMM
.|| ... .|  |||| ||.||||....  |..
lleavrgskgPivvhCsaGiGrtGtivaieyil
Phosphatase mbre_CDC14.AA Subfamily.N20.PD 509-562 37 7.2e-06 17.3 In-house 187-245 (257) Show / Hide 
Range on Protein: 509-562
Range on HMM: 187-245/257
Sequence Identity: 37% (22 aa)

KCTGTAVVHCKAGLGRTGSL-----IGCYMMKHYRFNAPETIAWLRIARPGSVIGPQQT
. ||  |||| ||.|||| .     . | ..|   ||  . .| .|  | | |   .| 
hltgpmvvhcsagigrtgvflcvdvvfcaivkncsfnimdivaqmreqrsgmvqtkeqy
Phosphatase mbre_CDC14.AA Subfamily.N5_RR.PD 510-565 30 8e-06 16.9 In-house 196-256 (265) Show / Hide 
Range on Protein: 510-565
Range on HMM: 196-256/265
Sequence Identity: 30% (18 aa)

CTGTAVVHCKAGLGRTGSLIGCYM----M-KHYRFNAPETIAWLRIARPGSVIGPQQTYLV
..  |||| ||.||||  |.  .    . ..   .  .... ||. | | |   .|  |. 
klaPvvvhcsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyeli
Phosphatase mbre_CDC14.AA Subfamily.N_Nematode_6.PD 503-532 48 9.8e-06 16.7 In-house 177-206 (253) Show / Hide 
Range on Protein: 503-532
Range on HMM: 177-206/253
Sequence Identity: 48% (13 aa)

FLEITEKCTGTAVVHCKAGLGRTGSLIGCY
.|..  |..   |||| ||.|||| |.   
llsvvkkdkkPivvhCsaGvGrtGtlalil
Sequence
Name Sequence Type Origin Length Description Download
mbre_CDC14.AA Protein None 711 None Fasta, JSON
mbre_CDC14.NA RNA None 2133 None Fasta, JSON
mbre_CDC14.AA.PD_314-571 Protein Phosphatase Domain None 258 None Fasta, JSON