mbre_4822
Species: M.brevicollis
Alias: mbre_4822
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: MKP-unclassified
Protein domain

Protein domains of mbre_4822.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Rhodanese mbre_4822.AA RHOD 190-313 16 3.1e-07 31.29 SMART 1-94 (94) Show / Hide
Range on Protein: 190-313
Range on HMM: 1-94/94
Sequence Identity: 16% (21 aa)

CNALHSILQWRPEQLLMLDCRAGLGFKTSSIKGAVSVQYSGLMLRRLRKQGHVRIQLKHLQVSDEAAVAKRSDPNTLVVVYDEDSTVVEPEGNAAILLRI
. ..   . .  |... .|||    .. . |.||. . .. |  |                        .  |... |.||.. .        |. . ..
V-PEWWKMLQN-EDCVIIDCRWPYEYEGGHIPGAINIPWDELLDR------------------------LGIDKDKPVIVYCRSGNRS-----APRAAWW

LESEGVK-AVFLKGGITAHRRLYAQ
|.. | | . .|.||... .| . .
LREAGYKNVYILDGGWKEWKRACPP

Phosphatase mbre_4822.AA Family.DSP.PD 338-487 25 6.1e-28 88.7 In-house 101-251 (387) Show / Hide
Range on Protein: 338-487
Range on HMM: 101-251/387
Sequence Identity: 25% (39 aa)

RLATVPATVVFDHLVLGNQHQGTDPAFLARNRITHVINVTETPFA--NglPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSR
|..  . . ...|| ||. .. ..   |.....|...|.|. .    .   . .. ..||. |.   .| ... .|..||| .....|.||| || .|  
rvengkpseilphlylgsllaaknlewlkelgvtkivnltddkpqftk--elgikylripidDhnapplenlfekaidfieegndskgvVlVHCkaGkgR

AVAVVMAYMMATRSYNYDAALQLLQAIRP-RIAPHDSFLKQLRDFQSFLSNAQ
 ...||.|  . .....||....  ||  | | . ||||| |... ... .  
sgtliiaYlmksegltleealdwvrskRpgvitpnqgflkqlkdlekeklkvs

Phosphatase mbre_4822.AA Subfamily.DSP19.PD 345-480 37 5.7e-33 104.2 In-house 3-137 (139) Show / Hide
Range on Protein: 345-480
Range on HMM: 3-137/139
Sequence Identity: 37% (51 aa)

TVVFDHLVLGNQHQGTDPAFLARNRITHVINVTETpFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYM
..| ..| || |   .|   | ...|||..||.     |  |. .....|..||   ..|||. .||| |||  |...||||| |. | ||...||.||.
aevkprlylgsqdvaadkeilkklkitHilnvavg-vpnvfpkdftyksieilDlpetkllsylkealdFieearskdgrvlvHCnAGvSRsasvviayl

MATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQ
|.... ..  ||. ... || | |   |.|||....
mkdeelslekalekvrearpcikPneGFikqLkeye

Phosphatase mbre_4822.AA Subfamily.DSP6.PD 347-481 30 3.1e-30 95.2 In-house 5-140 (141) Show / Hide
Range on Protein: 347-481
Range on HMM: 5-140/141
Sequence Identity: 30% (42 aa)

VFDHLVLGNQHQGTDPAFLARNRITHVINVTET-PFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMM
. ..| ||.... ..   |.. .| .|.|||.  | .    . .. .|||. | ....| . .|||..||. .|...  |||.|  | ||.|.|..||.|
ilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkykqipiedhlsqnlakffPeaiefidearskkskvlvhclaGvsrsvtvtlaylm

ATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQS
 ....  . | .|... .. |.|  .|..|| ||..
kklalslndaydlvkkkksnisPnfnfmgqlldfer

Phosphatase mbre_4822.AA DSPc 343-482 27 3.5e-30 107.5 SMART 1-172 (172) Show / Hide
Range on Protein: 343-482
Range on HMM: 1-172/172
Sequence Identity: 27% (47 aa)

PATVVFDHLVLGNQHQGT--DPAFLARNRITHVINVT-ETPFANGLP---------------NLVRCMQIP-LLD-------GAHHDLLSVVPEALRFIE
. . .  || ||..   .  .|.||. . |||||||| | | .. ..                  . |.|| . |           ...   ||. .||.
GPSEITPHLYLGSYPHHMEPNPCFLKKHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFIH

GCRREHGRVLVYCSNGYSRAVAVVMAYMMATRSYNYDAALQLL-----QAIR-PRIAPHDSFLKQLRDFQSF
 ||...|.|||.|  |.|| .....||.| .....|..|. ..     . .| | | | ..|..||.... .
DCRQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK

Phosphatase mbre_4822.AA Subfamily.DSP1.PD 346-481 30 1e-29 93.8 In-house 5-138 (139) Show / Hide
Range on Protein: 346-481
Range on HMM: 5-138/139
Sequence Identity: 30% (41 aa)

VVfDHLVLGNQHQGTDPAFLARNRITHVINVTETpFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMM
.. |.| || ... .. ..|.. .||...||...   |  ..| . ..||. |  . |..| . ||. ||. .....|||||.|  | ||...|.||.| 
il-dfLyLGsaehasnlqlLkelkitallnvsae-lpnvfeelfkyksipvednkkadisslfeeaidfidsvkkkgGrvlvhCqaGisrsativlayLm

ATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQS
.. .... | . ..  |  |.|  .|..||  |.. 
kekkvrleeafefvkqrrsiisPnfgfvgqLlefek

Phosphatase mbre_4822.AA DSPc 351-482 30 1.5e-29 104.66 Pfam 1-151 (151) Show / Hide
Range on Protein: 351-482
Range on HMM: 1-151/151
Sequence Identity: 30% (48 aa)

LVLGNQHQGT-DPAFLARNRITHVINVT-ETP-FANGLPNL-----VRCMQIP-LLD---------GAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNG
| ||..   . |||||. . ||||||.| | | .     ..      . |.|| ..|             ..    |.|  ||. ||...|.|||.|  |
LYLGSYPHHMADPAFLQKHGITHVINCTMECPNN-----WFYHNSHFHYMWIPHVHDHIHYYHIHWNHCTNISQYFPMATDFIDDCRQKGGKVLVHCQAG

YSRAVAVVMAYMMATRSYNYDAALQLL-----QAIR-PRIAPHDSFLKQLRDFQSF
.|| .....||.| .| ..|. |. ..     .  | | | | ..|..||.... .
ISRSACLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ

Phosphatase mbre_4822.AA Subfamily.DSP12.PD 347-481 33 1.9e-29 93.1 In-house 5-140 (143) Show / Hide
Range on Protein: 347-481
Range on HMM: 5-140/143
Sequence Identity: 33% (45 aa)

VFDHLVLGNQHQGTDPAFLARNRITHVINVTETPF--ANGLPNLVRcMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYM
. . | ||. .. .... |.   ||||. |....    .  .. ..  .|..||  . |||| ..||.|||| .. ..| ||| |  | |||..|.||.|
ilpglylggleavqerellkelkithvlsvikeelpelqkekgvks-kliqilDepeedlLshldeavrFieeglekegavlvHClagvSRSvtiviAYl

MATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQS
 ..  . . ||.|.......| | ..||.||. |.  
mkkeklslekAlklvkekkkeiepNegFleQLklfek

Phosphatase mbre_4822.AA Subfamily.DSP10.PD 343-480 37 2e-29 92.8 In-house 1-139 (141) Show / Hide
Range on Protein: 343-480
Range on HMM: 1-139/141
Sequence Identity: 37% (52 aa)

PATVVFDHLVLGNQHQGTDPAFLARNRITHVINVTE-TPFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVM
||. .. .|.|||... .|   | |  |..|.|||  .|      .||| ..||. |  ...|     ||| |||  |.. .||||.|  |||...||.|
passilpflllGnekdaadkdaldrlgikyvlnvttsvPnffeekglvrykripvsdsgkqnlkqkfeealefieearkrgsrvlvhchaGisrsatvvi

AYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQ
|.|.  |     | ....  || |.|  .|. || .|. 
ayvmkhlslslseaykfvkekrPiisPnlnfmGqllefe

Phosphatase mbre_4822.AA Subfamily.DSP8.PD 345-480 34 1.4e-26 83.7 In-house 3-139 (143) Show / Hide
Range on Protein: 345-480
Range on HMM: 3-139/143
Sequence Identity: 34% (47 aa)

TVVFDHLVLGNQHQGTDPAFLARNRITHVINVTET-PFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAY
| . ..| || |..  |  .| .. |..|.|..|. |    | . .| ..||. |  . .|| . ..|| ||. .|...|.|||.|  | ||. .|..||
trilpnlylGsqkdsldeellkklgisyvlnisescpkdvellkesrflriPvkDkyeekllpwfdkalefidkarsangkvlvhclaGisrsatvaiay

MMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQ
.| | . ..| | . ..  || | |   || || ...
imktlemsldeayrfvkekrptispnlnflgqLleye

Phosphatase mbre_4822.AA Subfamily.Slingshot.PD 344-480 32 6.4e-25 78.1 In-house 2-137 (139) Show / Hide
Range on Protein: 344-480
Range on HMM: 2-137/139
Sequence Identity: 32% (44 aa)

ATVVFDHLVLGNQHQGTDPAFLARNRITHVINVTETpFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAY
|. .|||| || .   ..   | .|......|||.    |  |. .. ..| . |  ..|||.   |. .||| ..... .|||.|| ||. ..|.|| |
askifdhlylGsewnasnleelkengveyilnvtke-idnffpekfkylnirvydeeetdllkhwnetykfiekakekgskvlvhckmGvsrsastviay

MMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQ
 . ..... ||. ..  |  | | ..|||||. ..  
amkeyelsleealeyvkerrsiikpnkgflkqlkvye

Phosphatase mbre_4822.AA Subfamily.DSP15.PD 347-481 31 1.3e-24 77.2 In-house 5-137 (138) Show / Hide
Range on Protein: 347-481
Range on HMM: 5-137/138
Sequence Identity: 31% (43 aa)

VFDHLVLGNQHQGTDPAFLARNRITHVINVTETPFAnGLPNlVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMMA
|   | .|| ..  | . | .|.|||.. . ...    |.. .. . |.  |  . || .   |.  ||  || | | |||.|  | ||.|..|.||.|.
vlpGlyvGnfrdakdkeqleenkithilsihdsakp-lled-ikylcikaadsPdqdlskffkesidfihkcrleggnvlvhclaGisrsvtlvvayimt

TRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQS
  ..... ||. ..| |.   |   | .||..|..
vtelswedalkavkaarsvanPnvGfrrqlqefek

Phosphatase mbre_4822.AA Subfamily.DSP14.PD 348-480 29 3.8e-24 75.8 In-house 6-136 (138) Show / Hide
Range on Protein: 348-480
Range on HMM: 6-136/138
Sequence Identity: 29% (38 aa)

FDHLVLGnQHQGTDPAFLARNRITHVINVTETPFANGLPNlVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMMAT
..| |.     .... |....||...|||    .  |.. |. ..|.. |  ...| .   |.   ||  ....|..||.| .| ||. ..|.||.|  .
tesLyls-gaaalkkeklkkkkitlivnvttelpetkled-vktvkikveDkpeaklaehfdevadkieevkkkgGktlvhCvaGvsRsAslvlaylmky

RSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQ
. .   | .|... || | |   | |||.|.  
eklsLreayklvksaRpiirPnvGFwkqlidyE

Phosphatase mbre_4822.AA Subfamily.STYXL1.PD 343-479 29 8.9e-24 74.8 In-house 2-140 (143) Show / Hide
Range on Protein: 343-479
Range on HMM: 2-140/143
Sequence Identity: 29% (40 aa)

PATVVFDHLVLGNQHQGTDPAFLARNRITHVINVTET--PFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVV
|  |. ..| ||| .| ..||     ..  ..||.    .. .||.. .. ..|.. |  . |||. . |. .|||  ..|   |||..| ||..||..|
PvevlPgklylGnykqaqnpaikkdlkvkahvnvssdaekliagladvakllhiavedeneadllerlkevvqfiekhkkegevvlvfsnkGisrsaavi

MAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDF
|.|  .  ..  |.. |.  .. . |. .|..||...  
iaylmyskkitlkkaykylkkckenvkPnrafveqlseW

Phosphatase mbre_4822.AA Subfamily.LRR-DSP.PD 346-480 33 1.3e-21 67.4 In-house 4-135 (137) Show / Hide
Range on Protein: 346-480
Range on HMM: 4-135/137
Sequence Identity: 33% (45 aa)

VVFDHLVLGNQHQGTDPAFLARNRITHVINVTEtpFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRrEHGRVLVYCSNGYSRAVAVVMAYMM
. |.| || ..  .. ..|  | .||.. |..  |    |.| . . | . |  . |.     |   ||.  | |.| ||..|  | ||. ..|.||.| 
liidklylgcresamnksilkdnnvthilavad--fkplypdlfkyliidiedvdeadiyqhfkemnafidegr-ekggvlihcragvsrsatlviaylm

ATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQ
 .| ..  ||.| .  |||| |   ||.||. |. 
kknslkfkealdlvikkrpriypnrgfldqlkkfe

Phosphatase mbre_4822.AA Subfamily.DSP3.PD 347-480 27 1.7e-18 57.5 In-house 5-146 (148) Show / Hide
Range on Protein: 347-480
Range on HMM: 5-146/148
Sequence Identity: 27% (39 aa)

VFDHLVLGNQHQGTDPAFLARNRITHVINVTETPF---ANGLPNL-----VRCMQIPLLDGAHHDLLSVVPEALRFIEGC-RREHGRVLVYCSNGYSRAV
|.... .|...  .|   |..  ||||.| .|.      .. ..      .. . ..  |  . || .   ||  ||.   ....|.||| |.|.||. .
vypkvyvgdeavakdkekLkklGithvLnaaegkrllkvdtdaefYkdleikylGvevsDvpefdlskyfeeaadfidealsqkngkvlvhcvvGisRsa

AVVMAYMMATRSYNYDAALQLLQAIRpRIAPHDSFLKQLRDFQ
.|.||.| .|. .   |..  .  |  | | . |||||.... 
tlvlayLmirrkltlkeaiktvrkkr-eilPneGflkqLleld

Phosphatase mbre_4822.AA Subfamily.STYX.PD 364-480 28 2.2e-17 53.8 In-house 24-144 (146) Show / Hide
Range on Protein: 364-480
Range on HMM: 24-144/146
Sequence Identity: 28% (34 aa)

FLARNRITHVINVTETPFANG----LPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMMATRSYNYDAALQLL
| .. |||.. . ... ||     .|.  | . . . | .  ...  .|..  ||... .. |.|||.   | ||. |.|.||.| |   .|  | . .|
vlkehgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaalviayimetyglkyreafayv

QAIRPRIAPHDSFLKQLRDFQ
  |  |.| . | .||.... 
qerrfcinpnegfvsqlkeye

Phosphatase mbre_4822.AA Subfamily.PTPMT1.PD 389-480 25 3.3e-13 40.2 In-house 53-144 (146) Show / Hide
Range on Protein: 389-480
Range on HMM: 53-144/146
Sequence Identity: 25% (23 aa)

VRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQ
|. .|..  | ..   |  . |...|||  . .  .| |.|  | .|. ..| .|.| .. .. . | ..|...|| |  ... .. |.|. 
veqlqlatvDfteapslekleegvefiekvaskgssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpqirlkskqwralqefk

Phosphatase mbre_4822.AA Subfamily.DSP23.PD 362-482 21 3.4e-07 20.9 In-house 6-126 (128) Show / Hide
Range on Protein: 362-482
Range on HMM: 6-126/128
Sequence Identity: 21% (26 aa)

PAFLARNRITHVINVTET--PFANGLPNL-VRCMQIPlldGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMMATRSYNYDAALQL
||| . | .....|.   |. .  |.| .|...||     .   |  | . .| .|   .... | |.|  |. |. ...  |......  | |.  .. 
vqfladqGirvlvslttegapyseaapsltlrridip---dfcPPaleqvarlvriveeaekkeeavgvhcalGlGrtGtllacylvkeeglaaddaiae

LQAIRPRIAPHDSFLKQLRDFQSF
 |.         | ..|.. .   
vrkrrkGsietveqekavkdyeey

Phosphatase mbre_4822.AA Subfamily.CDC14.PD 413-473 22 4.9e-07 20.2 In-house 189-251 (258) Show / Hide
Range on Protein: 413-473
Range on HMM: 189-251/258
Sequence Identity: 22% (14 aa)

RFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMMATRSYNYDAALQLLQAIRPR--IAPHDSFL
.|.| . . .| . |.|  |  |  ... .|.. .  .. . ..  |. .||   |.| ...|
kfleitekaeGaiavhCkaGLGrtgtligcylikhyrftaaetiawlriarPGsvigpqqtyl

Phosphatase mbre_4822.AA Subfamily.PTPDC1.PD 421-484 22 1.5e-06 18.3 In-house 165-228 (229) Show / Hide
Range on Protein: 421-484
Range on HMM: 165-228/229
Sequence Identity: 22% (14 aa)

EHGRVLVYCSNGYSRAVAVVMAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSFLS
|.|.. |.|  |  |   .. .|.. .. .. . |..|... ||      . .. ...|. || 
eegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrpksiqtreqvelveeFalflr

Phosphatase mbre_4822.AA Subfamily.RNGTT.PD 424-477 26 2.6e-06 17.7 In-house 81-134 (140) Show / Hide
Range on Protein: 424-477
Range on HMM: 81-134/140
Sequence Identity: 26% (14 aa)

RVLVYCSNGYSRAVAVVMAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLR
. |.|  |. |.  ...||.. .  .. .||..|.   ||.    . .||.|  
vigvhCthGfnrtGflivayLvekedwsveaavalfakarppGiykedylkelf

Sequence
Name Sequence Type Origin Length Description Download
mbre_4822.AA Protein None 510 None Fasta, JSON
mbre_4822.NA RNA None 1530 None Fasta, JSON
mbre_4822.AA.PD2_343-482 Protein Phosphatase Domain None 140 None Fasta, JSON