Gene mbre_4822
mbre_4822
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of mbre_4822.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Rhodanese | mbre_4822.AA | RHOD | 190-313 | 16 | 3.1e-07 | 31.29 | SMART | 1-94 (94) | Show / Hide |
Range on Protein: 190-313 Range on HMM: 1-94/94 Sequence Identity: 16% (21 aa) CNALHSILQWRPEQLLMLDCRAGLGFKTSSIKGAVSVQYSGLMLRRLRKQGHVRIQLKHLQVSDEAAVAKRSDPNTLVVVYDEDSTVVEPEGNAAILLRI . .. . . |... .||| .. . |.||. . .. | | . |... |.||.. . |. . .. V-PEWWKMLQN-EDCVIIDCRWPYEYEGGHIPGAINIPWDELLDR------------------------LGIDKDKPVIVYCRSGNRS-----APRAAWW LESEGVK-AVFLKGGITAHRRLYAQ |.. | | . .|.||... .| . . LREAGYKNVYILDGGWKEWKRACPP |
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Phosphatase | mbre_4822.AA | Family.DSP.PD | 338-487 | 25 | 6.1e-28 | 88.7 | In-house | 101-251 (387) | Show / Hide |
Range on Protein: 338-487 Range on HMM: 101-251/387 Sequence Identity: 25% (39 aa) RLATVPATVVFDHLVLGNQHQGTDPAFLARNRITHVINVTETPFA--NglPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSR |.. . . ...|| ||. .. .. |.....|...|.|. . . . .. ..||. |. .| ... .|..||| .....|.||| || .| rvengkpseilphlylgsllaaknlewlkelgvtkivnltddkpqftk--elgikylripidDhnapplenlfekaidfieegndskgvVlVHCkaGkgR AVAVVMAYMMATRSYNYDAALQLLQAIRP-RIAPHDSFLKQLRDFQSFLSNAQ ...||.| . .....||.... || | | . ||||| |... ... . sgtliiaYlmksegltleealdwvrskRpgvitpnqgflkqlkdlekeklkvs |
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Phosphatase | mbre_4822.AA | Subfamily.DSP19.PD | 345-480 | 37 | 5.7e-33 | 104.2 | In-house | 3-137 (139) | Show / Hide |
Range on Protein: 345-480 Range on HMM: 3-137/139 Sequence Identity: 37% (51 aa) TVVFDHLVLGNQHQGTDPAFLARNRITHVINVTETpFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYM ..| ..| || | .| | ...|||..||. | |. .....|..|| ..|||. .||| ||| |...||||| |. | ||...||.||. aevkprlylgsqdvaadkeilkklkitHilnvavg-vpnvfpkdftyksieilDlpetkllsylkealdFieearskdgrvlvHCnAGvSRsasvviayl MATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQ |.... .. ||. ... || | | |.|||.... mkdeelslekalekvrearpcikPneGFikqLkeye |
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Phosphatase | mbre_4822.AA | Subfamily.DSP6.PD | 347-481 | 30 | 3.1e-30 | 95.2 | In-house | 5-140 (141) | Show / Hide |
Range on Protein: 347-481 Range on HMM: 5-140/141 Sequence Identity: 30% (42 aa) VFDHLVLGNQHQGTDPAFLARNRITHVINVTET-PFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMM . ..| ||.... .. |.. .| .|.|||. | . . .. .|||. | ....| . .|||..||. .|... |||.| | ||.|.|..||.| ilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkykqipiedhlsqnlakffPeaiefidearskkskvlvhclaGvsrsvtvtlaylm ATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQS .... . | .|... .. |.| .|..|| ||.. kklalslndaydlvkkkksnisPnfnfmgqlldfer |
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Phosphatase | mbre_4822.AA | DSPc | 343-482 | 27 | 3.5e-30 | 107.5 | SMART | 1-172 (172) | Show / Hide |
Range on Protein: 343-482 Range on HMM: 1-172/172 Sequence Identity: 27% (47 aa) PATVVFDHLVLGNQHQGT--DPAFLARNRITHVINVT-ETPFANGLP---------------NLVRCMQIP-LLD-------GAHHDLLSVVPEALRFIE . . . || ||.. . .|.||. . |||||||| | | .. .. . |.|| . | ... ||. .||. GPSEITPHLYLGSYPHHMEPNPCFLKKHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFIH GCRREHGRVLVYCSNGYSRAVAVVMAYMMATRSYNYDAALQLL-----QAIR-PRIAPHDSFLKQLRDFQSF ||...|.|||.| |.|| .....||.| .....|..|. .. . .| | | | ..|..||.... . DCRQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK |
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Phosphatase | mbre_4822.AA | Subfamily.DSP1.PD | 346-481 | 30 | 1e-29 | 93.8 | In-house | 5-138 (139) | Show / Hide |
Range on Protein: 346-481 Range on HMM: 5-138/139 Sequence Identity: 30% (41 aa) VVfDHLVLGNQHQGTDPAFLARNRITHVINVTETpFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMM .. |.| || ... .. ..|.. .||...||... | ..| . ..||. | . |..| . ||. ||. .....|||||.| | ||...|.||.| il-dfLyLGsaehasnlqlLkelkitallnvsae-lpnvfeelfkyksipvednkkadisslfeeaidfidsvkkkgGrvlvhCqaGisrsativlayLm ATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQS .. .... | . .. | |.| .|..|| |.. kekkvrleeafefvkqrrsiisPnfgfvgqLlefek |
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Phosphatase | mbre_4822.AA | DSPc | 351-482 | 30 | 1.5e-29 | 104.66 | Pfam | 1-151 (151) | Show / Hide |
Range on Protein: 351-482 Range on HMM: 1-151/151 Sequence Identity: 30% (48 aa) LVLGNQHQGT-DPAFLARNRITHVINVT-ETP-FANGLPNL-----VRCMQIP-LLD---------GAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNG | ||.. . |||||. . ||||||.| | | . .. . |.|| ..| .. |.| ||. ||...|.|||.| | LYLGSYPHHMADPAFLQKHGITHVINCTMECPNN-----WFYHNSHFHYMWIPHVHDHIHYYHIHWNHCTNISQYFPMATDFIDDCRQKGGKVLVHCQAG YSRAVAVVMAYMMATRSYNYDAALQLL-----QAIR-PRIAPHDSFLKQLRDFQSF .|| .....||.| .| ..|. |. .. . | | | | ..|..||.... . ISRSACLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ |
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Phosphatase | mbre_4822.AA | Subfamily.DSP12.PD | 347-481 | 33 | 1.9e-29 | 93.1 | In-house | 5-140 (143) | Show / Hide |
Range on Protein: 347-481 Range on HMM: 5-140/143 Sequence Identity: 33% (45 aa) VFDHLVLGNQHQGTDPAFLARNRITHVINVTETPF--ANGLPNLVRcMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYM . . | ||. .. .... |. ||||. |.... . .. .. .|..|| . |||| ..||.|||| .. ..| ||| | | |||..|.||.| ilpglylggleavqerellkelkithvlsvikeelpelqkekgvks-kliqilDepeedlLshldeavrFieeglekegavlvHClagvSRSvtiviAYl MATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQS .. . . ||.|.......| | ..||.||. |. mkkeklslekAlklvkekkkeiepNegFleQLklfek |
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Phosphatase | mbre_4822.AA | Subfamily.DSP10.PD | 343-480 | 37 | 2e-29 | 92.8 | In-house | 1-139 (141) | Show / Hide |
Range on Protein: 343-480 Range on HMM: 1-139/141 Sequence Identity: 37% (52 aa) PATVVFDHLVLGNQHQGTDPAFLARNRITHVINVTE-TPFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVM ||. .. .|.|||... .| | | |..|.||| .| .||| ..||. | ...| ||| ||| |.. .||||.| |||...||.| passilpflllGnekdaadkdaldrlgikyvlnvttsvPnffeekglvrykripvsdsgkqnlkqkfeealefieearkrgsrvlvhchaGisrsatvvi AYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQ |.|. | | .... || |.| .|. || .|. ayvmkhlslslseaykfvkekrPiisPnlnfmGqllefe |
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Phosphatase | mbre_4822.AA | Subfamily.DSP8.PD | 345-480 | 34 | 1.4e-26 | 83.7 | In-house | 3-139 (143) | Show / Hide |
Range on Protein: 345-480 Range on HMM: 3-139/143 Sequence Identity: 34% (47 aa) TVVFDHLVLGNQHQGTDPAFLARNRITHVINVTET-PFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAY | . ..| || |.. | .| .. |..|.|..|. | | . .| ..||. | . .|| . ..|| ||. .|...|.|||.| | ||. .|..|| trilpnlylGsqkdsldeellkklgisyvlnisescpkdvellkesrflriPvkDkyeekllpwfdkalefidkarsangkvlvhclaGisrsatvaiay MMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQ .| | . ..| | . .. || | | || || ... imktlemsldeayrfvkekrptispnlnflgqLleye |
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Phosphatase | mbre_4822.AA | Subfamily.Slingshot.PD | 344-480 | 32 | 6.4e-25 | 78.1 | In-house | 2-137 (139) | Show / Hide |
Range on Protein: 344-480 Range on HMM: 2-137/139 Sequence Identity: 32% (44 aa) ATVVFDHLVLGNQHQGTDPAFLARNRITHVINVTETpFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAY |. .|||| || . .. | .|......|||. | |. .. ..| . | ..|||. |. .||| ..... .|||.|| ||. ..|.|| | askifdhlylGsewnasnleelkengveyilnvtke-idnffpekfkylnirvydeeetdllkhwnetykfiekakekgskvlvhckmGvsrsastviay MMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQ . ..... ||. .. | | | ..|||||. .. amkeyelsleealeyvkerrsiikpnkgflkqlkvye |
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Phosphatase | mbre_4822.AA | Subfamily.DSP15.PD | 347-481 | 31 | 1.3e-24 | 77.2 | In-house | 5-137 (138) | Show / Hide |
Range on Protein: 347-481 Range on HMM: 5-137/138 Sequence Identity: 31% (43 aa) VFDHLVLGNQHQGTDPAFLARNRITHVINVTETPFAnGLPNlVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMMA | | .|| .. | . | .|.|||.. . ... |.. .. . |. | . || . |. || || | | |||.| | ||.|..|.||.|. vlpGlyvGnfrdakdkeqleenkithilsihdsakp-lled-ikylcikaadsPdqdlskffkesidfihkcrleggnvlvhclaGisrsvtlvvayimt TRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQS ..... ||. ..| |. | | .||..|.. vtelswedalkavkaarsvanPnvGfrrqlqefek |
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Phosphatase | mbre_4822.AA | Subfamily.DSP14.PD | 348-480 | 29 | 3.8e-24 | 75.8 | In-house | 6-136 (138) | Show / Hide |
Range on Protein: 348-480 Range on HMM: 6-136/138 Sequence Identity: 29% (38 aa) FDHLVLGnQHQGTDPAFLARNRITHVINVTETPFANGLPNlVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMMAT ..| |. .... |....||...||| . |.. |. ..|.. | ...| . |. || ....|..||.| .| ||. ..|.||.| . tesLyls-gaaalkkeklkkkkitlivnvttelpetkled-vktvkikveDkpeaklaehfdevadkieevkkkgGktlvhCvaGvsRsAslvlaylmky RSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQ . . | .|... || | | | |||.|. eklsLreayklvksaRpiirPnvGFwkqlidyE |
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Phosphatase | mbre_4822.AA | Subfamily.STYXL1.PD | 343-479 | 29 | 8.9e-24 | 74.8 | In-house | 2-140 (143) | Show / Hide |
Range on Protein: 343-479 Range on HMM: 2-140/143 Sequence Identity: 29% (40 aa) PATVVFDHLVLGNQHQGTDPAFLARNRITHVINVTET--PFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVV | |. ..| ||| .| ..|| .. ..||. .. .||.. .. ..|.. | . |||. . |. .||| ..| |||..| ||..||..| PvevlPgklylGnykqaqnpaikkdlkvkahvnvssdaekliagladvakllhiavedeneadllerlkevvqfiekhkkegevvlvfsnkGisrsaavi MAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDF |.| . .. |.. |. .. . |. .|..||... iaylmyskkitlkkaykylkkckenvkPnrafveqlseW |
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Phosphatase | mbre_4822.AA | Subfamily.LRR-DSP.PD | 346-480 | 33 | 1.3e-21 | 67.4 | In-house | 4-135 (137) | Show / Hide |
Range on Protein: 346-480 Range on HMM: 4-135/137 Sequence Identity: 33% (45 aa) VVFDHLVLGNQHQGTDPAFLARNRITHVINVTEtpFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRrEHGRVLVYCSNGYSRAVAVVMAYMM . |.| || .. .. ..| | .||.. |.. | |.| . . | . | . |. | ||. | |.| ||..| | ||. ..|.||.| liidklylgcresamnksilkdnnvthilavad--fkplypdlfkyliidiedvdeadiyqhfkemnafidegr-ekggvlihcragvsrsatlviaylm ATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQ .| .. ||.| . |||| | ||.||. |. kknslkfkealdlvikkrpriypnrgfldqlkkfe |
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Phosphatase | mbre_4822.AA | Subfamily.DSP3.PD | 347-480 | 27 | 1.7e-18 | 57.5 | In-house | 5-146 (148) | Show / Hide |
Range on Protein: 347-480 Range on HMM: 5-146/148 Sequence Identity: 27% (39 aa) VFDHLVLGNQHQGTDPAFLARNRITHVINVTETPF---ANGLPNL-----VRCMQIPLLDGAHHDLLSVVPEALRFIEGC-RREHGRVLVYCSNGYSRAV |.... .|... .| |.. ||||.| .|. .. .. .. . .. | . || . || ||. ....|.||| |.|.||. . vypkvyvgdeavakdkekLkklGithvLnaaegkrllkvdtdaefYkdleikylGvevsDvpefdlskyfeeaadfidealsqkngkvlvhcvvGisRsa AVVMAYMMATRSYNYDAALQLLQAIRpRIAPHDSFLKQLRDFQ .|.||.| .|. . |.. . | | | . |||||.... tlvlayLmirrkltlkeaiktvrkkr-eilPneGflkqLleld |
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Phosphatase | mbre_4822.AA | Subfamily.STYX.PD | 364-480 | 28 | 2.2e-17 | 53.8 | In-house | 24-144 (146) | Show / Hide |
Range on Protein: 364-480 Range on HMM: 24-144/146 Sequence Identity: 28% (34 aa) FLARNRITHVINVTETPFANG----LPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMMATRSYNYDAALQLL | .. |||.. . ... || .|. | . . . | . ... .|.. ||... .. |.|||. | ||. |.|.||.| | .| | . .| vlkehgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaalviayimetyglkyreafayv QAIRPRIAPHDSFLKQLRDFQ | |.| . | .||.... qerrfcinpnegfvsqlkeye |
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Phosphatase | mbre_4822.AA | Subfamily.PTPMT1.PD | 389-480 | 25 | 3.3e-13 | 40.2 | In-house | 53-144 (146) | Show / Hide |
Range on Protein: 389-480 Range on HMM: 53-144/146 Sequence Identity: 25% (23 aa) VRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQ |. .|.. | .. | . |...||| . . .| |.| | .|. ..| .|.| .. .. . | ..|...|| | ... .. |.|. veqlqlatvDfteapslekleegvefiekvaskgssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpqirlkskqwralqefk |
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Phosphatase | mbre_4822.AA | Subfamily.DSP23.PD | 362-482 | 21 | 3.4e-07 | 20.9 | In-house | 6-126 (128) | Show / Hide |
Range on Protein: 362-482 Range on HMM: 6-126/128 Sequence Identity: 21% (26 aa) PAFLARNRITHVINVTET--PFANGLPNL-VRCMQIPlldGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMMATRSYNYDAALQL ||| . | .....|. |. . |.| .|...|| . | | . .| .| .... | |.| |. |. ... |...... | |. .. vqfladqGirvlvslttegapyseaapsltlrridip---dfcPPaleqvarlvriveeaekkeeavgvhcalGlGrtGtllacylvkeeglaaddaiae LQAIRPRIAPHDSFLKQLRDFQSF |. | ..|.. . vrkrrkGsietveqekavkdyeey |
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Phosphatase | mbre_4822.AA | Subfamily.CDC14.PD | 413-473 | 22 | 4.9e-07 | 20.2 | In-house | 189-251 (258) | Show / Hide |
Range on Protein: 413-473 Range on HMM: 189-251/258 Sequence Identity: 22% (14 aa) RFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMMATRSYNYDAALQLLQAIRPR--IAPHDSFL .|.| . . .| . |.| | | ... .|.. . .. . .. |. .|| |.| ...| kfleitekaeGaiavhCkaGLGrtgtligcylikhyrftaaetiawlriarPGsvigpqqtyl |
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Phosphatase | mbre_4822.AA | Subfamily.PTPDC1.PD | 421-484 | 22 | 1.5e-06 | 18.3 | In-house | 165-228 (229) | Show / Hide |
Range on Protein: 421-484 Range on HMM: 165-228/229 Sequence Identity: 22% (14 aa) EHGRVLVYCSNGYSRAVAVVMAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSFLS |.|.. |.| | | .. .|.. .. .. . |..|... || . .. ...|. || eegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrpksiqtreqvelveeFalflr |
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Phosphatase | mbre_4822.AA | Subfamily.RNGTT.PD | 424-477 | 26 | 2.6e-06 | 17.7 | In-house | 81-134 (140) | Show / Hide |
Range on Protein: 424-477 Range on HMM: 81-134/140 Sequence Identity: 26% (14 aa) RVLVYCSNGYSRAVAVVMAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLR . |.| |. |. ...||.. . .. .||..|. ||. . .||.| vigvhCthGfnrtGflivayLvekedwsveaavalfakarppGiykedylkelf |
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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mbre_4822.AA | Protein | None | 510 | None | Fasta, JSON |
mbre_4822.NA | RNA | None | 1530 | None | Fasta, JSON |
mbre_4822.AA.PD2_343-482 | Protein Phosphatase Domain | None | 140 | None | Fasta, JSON |