Gene mbre_MKP_25952
mbre_MKP_25952
Species: M.brevicollis
Alias: mbre_MKP_25952
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of mbre_MKP_25952.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | mbre_MKP_25952.AA | Family.DSP.PD | 213-364 | 39 | 2.2e-37 | 119.9 | In-house | 101-253 (387) | Show / Hide |
Range on Protein: 213-364 Range on HMM: 101-253/387 Sequence Identity: 39% (60 aa) FTDAEFPSEIKDgFLFLGSWKSASNLEALKALNITRIVNATASCDMPFD-QQAVYLHCPLDDKPDHDLSQFFGDFIAFVRKAQGEGQRVLVHCQMGMSRS . . |||| . .|.|||.. |.|||.|| |..|.|||.| .. .. ||..|.|| . .|...| .| |. ... ....|||||..|.|| rvengkpseilp-hlylgsllaaknlewlkelgvtkivnltddkpqftkelgikylripidDhnapplenlfekaidfieegndskgvVlVHCkaGkgRs SALAILWMMDFHDMTLKQAYDYVHSKRP-YINPNPGFLKQLGEWEHANRGSSTI | | ..| ....||..|.|.| |||| |.|| |||||| ..|. .. |.. gtliiaYlmksegltleealdwvrskRpgvitpnqgflkqlkdlekeklkvsse |
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| Phosphatase | mbre_MKP_25952.AA | Subfamily.DSP1.PD | 219-356 | 39 | 2.7e-42 | 134.8 | In-house | 2-138 (139) | Show / Hide |
Range on Protein: 219-356 Range on HMM: 2-138/139 Sequence Identity: 39% (54 aa) PSEIKdGFLFLGSWKSASNLEALKALNITRIVNATASCDMPFDQQAVYLHCPLDDKPDHDLSQFFGDFIAFVRKAQGEGQRVLVHCQMGMSRSSALAILW |.|| ||.||| ..||||. ||.|.|| ..| .|... |... | . |..|... |.|..| . | |. ... .| |||||||.|.|||... ... pveil-dfLyLGsaehasnlqlLkelkitallnvsaelpnvfeelfkyksipvednkkadisslfeeaidfidsvkkkgGrvlvhCqaGisrsativlay MMDFHDMTLKQAYDYVHSKRPYINPNPGFLKQLGEWEH .| . ..|..|...|...| |.|| ||..|| |.|. LmkekkvrleeafefvkqrrsiisPnfgfvgqLlefek |
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| Phosphatase | mbre_MKP_25952.AA | DSPc | 218-357 | 32 | 3.3e-42 | 147.45 | SMART | 1-172 (172) | Show / Hide |
Range on Protein: 218-357 Range on HMM: 1-172/172 Sequence Identity: 32% (56 aa) FPSEIKDGFLFLGSWKSAS--NLEALKALNITRIVNATASCDMPFD-----------------QQAVYLHCP-LDD-------KPDHDLSQFFGDFIAFV |||| . |.|||..... |.. ||..||| ..|.|..|. .| . |.|.| .|| . ..||.| ..|. GPSEITPH-LYLGSYPHHMEPNPCFLKKHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFI RKAQGEGQRVLVHCQMGMSRSSALAILWMMDFHDMTLKQAYDYV-----HSKR-PYINPNPGFLKQLGEWEHA ... .| .||||||.| ||| .|.| ..|. . |.. ||..| ...| | |.|| .|..|| ||| HDCRQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK |
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| Phosphatase | mbre_MKP_25952.AA | DSPc | 227-357 | 30 | 2.8e-41 | 145.43 | Pfam | 1-151 (151) | Show / Hide |
Range on Protein: 227-357 Range on HMM: 1-151/151 Sequence Identity: 30% (46 aa) LFLGSWKSAS-NLEALKALNITRIVNATASCDMPFD---QQAVYLHCP-LDD---------KPDHDLSQFFGDFIAFVRKAQGEGQRVLVHCQMGMSRSS |.|||..... ... |....|| ..|.| .|. ... |...| ..| .. ..||.| ..|.......| .||||||.| ||| LYLGSYPHHMADPAFLQKHGITHVINCTMECPNNWFYHNSHFHYMWIPHVHDHIHYYHIHWNHCTNISQYFPMATDFIDDCRQKGGKVLVHCQAGISRSA ALAILWMMDFHDMTLKQAYDYV-----HSKR-PYINPNPGFLKQLGEWEHA .|.| ..|. . |... |||.| ..| | |.||..|..|| |.| CLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ |
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| Phosphatase | mbre_MKP_25952.AA | Subfamily.DSP19.PD | 226-355 | 36 | 2.2e-35 | 112.2 | In-house | 8-137 (139) | Show / Hide |
Range on Protein: 226-355 Range on HMM: 8-137/139 Sequence Identity: 36% (47 aa) FLFLGSWKSASNLEALKALNITRIVNATASCDMPFDQQAVYLHCPLDDKPDHDLSQFFGDFIAFVRKAQGEGQRVLVHCQMGMSRSSALAILWMMDFHDM .|.||| .|...|.|| |.|| |.| .. . | .. |.. .. |.|...| ... . . |...|. .. ||||||. |.|||....|..| .... rlylgsqdvaadkeilkklkitHilnvavgvpnvfpkdftyksieilDlpetkllsylkealdFieearskdgrvlvHCnAGvSRsasvviaylmkdeel TLKQAYDYVHSKRPYINPNPGFLKQLGEWE |..|...|...|| |.|| ||.||| |.| slekalekvrearpcikPneGFikqLkeye |
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| Phosphatase | mbre_MKP_25952.AA | Subfamily.DSP14.PD | 222-356 | 33 | 3.2e-35 | 111.9 | In-house | 5-137 (138) | Show / Hide |
Range on Protein: 222-356 Range on HMM: 5-137/138 Sequence Identity: 33% (45 aa) IKDgFLFLGsWKSASNLEALKALNITRIVNATASCDMPFDQQAVYLHCPLDDKPDHDLSQFFGDFIAFVRKAQGEGQRVLVHCQMGMSRSSALAILWMMD |.. |.|. ..|.. |.||. .|| |||.| . .. ... ...|||...|...| . ..... .| ..|||| .|.|||.|.. ..| . ite-sLyls-gaaalkkeklkkkkitlivnvttelpetkledvktvkikveDkpeaklaehfdevadkieevkkkgGktlvhCvaGvsRsAslvlaylmk FHDMTLKQAYDYVHSKRPYINPNPGFLKQLGEWEH . ..|..|| .|.|.|| |.||.|| ||| ..|. yeklsLreayklvksaRpiirPnvGFwkqlidyEk |
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| Phosphatase | mbre_MKP_25952.AA | Subfamily.DSP10.PD | 226-356 | 38 | 3.3e-35 | 111.7 | In-house | 8-140 (141) | Show / Hide |
Range on Protein: 226-356 Range on HMM: 8-140/141 Sequence Identity: 38% (51 aa) FLFLGSWKSASNLEALKALNITRIVNATASCDMPFDQQA-V-YLHCPLDDKPDHDLSQFFGDFIAFVRKAQGEGQRVLVHCQMGMSRSSALAILWMMDFH ||.||. | |.. .||. |.|. ..| |.|. . |... | | . |. |.. ..|.| | . ..|. .|. .|.||||||. |.|||....| ..| . flllGnekdaadkdaldrlgikyvlnvttsvPnffeekglvrykripvsdsgkqnlkqkfeealefieearkrgsrvlvhchaGisrsatvviayvmkhl DMTLKQAYDYVHSKRPYINPNPGFLKQLGEWEH ...|..|| .| .||| | || .|. || |.|. slslseaykfvkekrPiisPnlnfmGqllefek |
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| Phosphatase | mbre_MKP_25952.AA | Subfamily.DSP6.PD | 219-356 | 37 | 1.8e-34 | 109.1 | In-house | 2-140 (141) | Show / Hide |
Range on Protein: 219-356 Range on HMM: 2-140/141 Sequence Identity: 37% (52 aa) PSEIKDgFLFLGSWKSASNLEALKALNITRIVNATASCDMPFDQQA--VYLHCPLDDKPDHDLSQFFGDFIAFVRKAQGEGQRVLVHCQMGMSRSSALAI | || . .|.||| |.|||||.|| |.| ...| | . |... |.. |..|. ..|..|| . |.|. .|. . . ||||| |.||| .... pveilp-llylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkykqipiedhlsqnlakffPeaiefidearskkskvlvhclaGvsrsvtvtl LWMMDFHDMTLKQAYDYVHSKRPYINPNPGFLKQLGEWEH ..|. . ..|..|||.|..|.. | || |..|| ..|. aylmkklalslndaydlvkkkksnisPnfnfmgqlldfer |
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| Phosphatase | mbre_MKP_25952.AA | Subfamily.Slingshot.PD | 219-355 | 40 | 2e-34 | 109.1 | In-house | 2-137 (139) | Show / Hide |
Range on Protein: 219-355 Range on HMM: 2-137/139 Sequence Identity: 40% (55 aa) PSEIKDgFLFLGSWKSASNLEALKALNITRIVNATASCDMPFDQQAVYLHCPLDDKPDHDLSQFFGDFIAFVRKAQGEGQRVLVHCQMGMSRSSALAILW .|.| | .|.||| ||||| || ... |.| | .| |... ||. . |....|| ... . |..||. .| .|||||.||.|||.. | . askifd-hlylGsewnasnleelkengveyilnvtkeidnffpekfkylnirvydeeetdllkhwnetykfiekakekgskvlvhckmGvsrsastviay MMDFHDMTLKQAYDYVHSKRPYINPNPGFLKQLGEWE | ....|..|..||...| |.|| |||||| ..| amkeyelsleealeyvkerrsiikpnkgflkqlkvye |
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| Phosphatase | mbre_MKP_25952.AA | Subfamily.DSP8.PD | 225-356 | 38 | 2.5e-32 | 102.5 | In-house | 7-140 (143) | Show / Hide |
Range on Protein: 225-356 Range on HMM: 7-140/143 Sequence Identity: 38% (51 aa) GFLFLGSWKSASNLEALKALNITRIVNATASCDM--PFDQQAVYLHCPLDDKPDHDLSQFFGDFIAFVRKAQGEGQRVLVHCQMGMSRSSALAILWMMDF .|.||| | . . |.||.|.|. ..|.. ||.. . ... .|..|. || . .|...| . |. ||. . ..||||| |.|||...|| ..| pnlylGsqkdsldeellkklgisyvlnisescpkdvellkesrflriPvkDkyeekllpwfdkalefidkarsangkvlvhclaGisrsatvaiayimkt HDMTLKQAYDYVHSKRPYINPNPGFLKQLGEWEH .|.| .|| .|..||| |.|| || || |.|. lemsldeayrfvkekrptispnlnflgqLleyek |
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| Phosphatase | mbre_MKP_25952.AA | Subfamily.LRR-DSP.PD | 219-356 | 37 | 3.2e-31 | 98.7 | In-house | 2-136 (137) | Show / Hide |
Range on Protein: 219-356 Range on HMM: 2-136/137 Sequence Identity: 37% (52 aa) PSEIKDGfLFLGSWKSASNLEALKALNITRIvNATASCDMPFDQQAVYLHCPLDDKPDHDLSQFFGDFIAFVRKAQGEGQrVLVHCQMGMSRSSALAILW |..| |. |.||. .|| | || .|.| | | | .. . . || ..| .. |..|.| . ||. . . .| ||.||. |.|||..|.| . pdliidk-lylgcresamnksilkdnnvthi-lavadfkplypdlfkyliidiedvdeadiyqhfkemnafidegrekgg-vlihcragvsrsatlviay MMDFHDMTLKQAYDYVHSKRPYINPNPGFLKQLGEWEH .| . ...|.|.| | .||| |.||.|||.|| .|. lmkknslkfkealdlvikkrpriypnrgfldqlkkfek |
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| Phosphatase | mbre_MKP_25952.AA | Subfamily.DSP12.PD | 221-356 | 29 | 4.8e-30 | 95.2 | In-house | 4-140 (143) | Show / Hide |
Range on Protein: 221-356 Range on HMM: 4-140/143 Sequence Identity: 29% (41 aa) EIKDGfLFLGSWKSASNLEALKALNITRIVNATASC--DMPFDQQAVYLHCPLDDKPDHDLSQFFGDFIAFVRKAQGEGQRVLVHCQMGMSRSSALAILW ||..| |.||. . . . | || |.||... . .. ... ... ...|.|. || ... . ..|. .. ... |||||..|.|||... | . eilpg-lylggleavqerellkelkithvlsvikeelpelqkekgvkskliqilDepeedlLshldeavrFieeglekegavlvHClagvSRSvtiviAY MMDFHDMTLKQAYDYVHSKRPYINPNPGFLKQLGEWEH .| ... |..|.. |..|.. |.|| |||.|| .|. lmkkeklslekAlklvkekkkeiepNegFleQLklfek |
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| Phosphatase | mbre_MKP_25952.AA | Subfamily.DSP15.PD | 227-356 | 37 | 1.8e-28 | 89.9 | In-house | 9-137 (138) | Show / Hide |
Range on Protein: 227-356 Range on HMM: 9-137/138 Sequence Identity: 37% (48 aa) LFLGSWKSASNLEALKALNITRIVNATASCDmPFDQQAVYLHCPLDDKPDHDLSQFFGDFIAFVRKAQGEGQRVLVHCQMGMSRSSALAILWMMDFHDMT |..|... |.. | |. .|| |. | . |. .. || . .| || |||.|| . | |. |.. ||. ||||| |.||| .|....| ... lyvGnfrdakdkeqleenkithilsihdsak-plledikylcikaadsPdqdlskffkesidfihkcrleggnvlvhclaGisrsvtlvvayimtvtels LKQAYDYVHSKRPYINPNPGFLKQLGEWEH ..| |.. |. ||| || .|| |.|. wedalkavkaarsvanPnvGfrrqlqefek |
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| Phosphatase | mbre_MKP_25952.AA | Subfamily.DSP3.PD | 227-355 | 35 | 9.3e-28 | 87.7 | In-house | 9-146 (148) | Show / Hide |
Range on Protein: 227-355 Range on HMM: 9-146/148 Sequence Identity: 35% (50 aa) LFLGSWKSASNLEALKALNITRIVNATASCD-------MPF--DQQAVYLHCPLDDKPDHDLSQFFGDFIAFVRKAQGE-GQRVLVHCQMGMSRSSALAI ...| ..|.. | ||.| || ..||. .. | | . || . .| |. |||..| |. .| . . .|||||..|.|||..|.. vyvgdeavakdkekLkklGithvLnaaegkrllkvdtdaefYkdleikylGvevsDvpefdlskyfeeaadfidealsqkngkvlvhcvvGisRsatlvl LWMMDFHDMTLKQAYDYVHSKRpYINPNPGFLKQLGEWE ..| ....|||.| |..|| | || |||||| | . ayLmirrkltlkeaiktvrkkr-eilPneGflkqLleld |
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| Phosphatase | mbre_MKP_25952.AA | Subfamily.STYXL1.PD | 218-356 | 33 | 1.1e-27 | 87.7 | In-house | 1-142 (143) | Show / Hide |
Range on Protein: 218-356 Range on HMM: 1-142/143 Sequence Identity: 33% (47 aa) FPSEIKDGFLFLGSWKSASNLEALKALNITRIVNATASCDMPFDQQ---AVYLHCPLDDKPDHDLSQFFGDFIAFVRKAQGEGQRVLVHCQMGMSRSSAL .|.|. |.|.|| .| | | . | | . || . .. .. . | ||....|... || ... . . |. | . ||. |||. |.||| |..| yPvevlPgklylGnykqaqnpaikkdlkvkahvnvssdaekliagladvakllhiavedeneadllerlkevvqfiekhkkegevvlvfsnkGisrsaav AILWMMDFHDMTLKQAYDYVHSKRPYINPNPGFLKQLGEWEH ..| ...|||.||.|.. .. ..|| .|..|| |||. iiaylmyskkitlkkaykylkkckenvkPnrafveqlseWek |
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| Phosphatase | mbre_MKP_25952.AA | Subfamily.STYX.PD | 227-355 | 33 | 1e-21 | 68.0 | In-house | 9-144 (146) | Show / Hide |
Range on Protein: 227-355 Range on HMM: 9-144/146 Sequence Identity: 33% (46 aa) LFLGSWKSA--SNLEALKALNITRIVNATASC-----DMPFDQQAVYLHCPLDDKPDHDLSQFFGDFIAFVRKAQGEGQRVLVHCQMGMSRSSALAILWM |||| . .| |.|| || || || . |... || . |.. .. ... .|. .. .| .|||| . |.|||.|| | .. lflgpysaamksklevlkehgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaalviayi MDFHDMTLKQAYDYVHSKRPYINPNPGFLKQLGEWE |. . . ..|. || .| |||| || .|| |.| metyglkyreafayvqerrfcinpnegfvsqlkeye |
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| Phosphatase | mbre_MKP_25952.AA | Subfamily.PTPMT1.PD | 285-351 | 26 | 2.3e-14 | 44.1 | In-house | 74-140 (146) | Show / Hide |
Range on Protein: 285-351 Range on HMM: 74-140/146 Sequence Identity: 26% (18 aa) DFIAFVRKAQGEGQRVLVHCQMGMSRSSALAILWMMDFHDMTLKQAYDYVHSKRPYINPNPGFLKQL . . |. | . .|..| |||. | .||..|.. ..| . .. ..| .....|||.| . .. | egvefiekvaskgssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpqirlkskqwral |
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| Phosphatase | mbre_MKP_25952.AA | Subfamily.Laforin.PD | 266-340 | 21 | 2.8e-07 | 21.1 | In-house | 73-147 (165) | Show / Hide |
Range on Protein: 266-340 Range on HMM: 73-147/165 Sequence Identity: 21% (16 aa) YLHCPLDDKPDHDLSQFFGDFIAFVRKAQGEGQRVLVHCQMGMSRSSALAILWMMDFHDMTLKQAYDYVHSKRPY |. |..| . . . . .. .|..| |||. |. ||.|. ... . .|.. .. .||| yiwlptedlstesrvenlpqavyllhallekghivyvhcnagvgrstaivcgflqyvlgwslakvqyfllakrpv |
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| Phosphatase | mbre_MKP_25952.AA | Subfamily.DSP11.PD | 267-342 | 21 | 8.5e-07 | 19.6 | In-house | 50-126 (141) | Show / Hide |
Range on Protein: 267-342 Range on HMM: 50-126/141 Sequence Identity: 21% (16 aa) LHCPLDDKPDHDLSQFFGDFI-AFVRKAQGEGQRVLVHCQMGMSRSSALAILWMMDFHDMTLKQAYDYVHSKRPYIN |.|| . |... . | ... |. | . ... . ||| |. |. | ...| ... ..| . .. | . lncpGhevpekedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyspedaieafeearGhsl |
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| Phosphatase | mbre_MKP_25952.AA | Subfamily.PTPDC1.PD | 265-339 | 26 | 3.1e-06 | 17.5 | In-house | 136-208 (229) | Show / Hide |
Range on Protein: 265-339 Range on HMM: 136-208/229 Sequence Identity: 26% (20 aa) VYLHCPLDDKPDHDLSQFFgDFIAFVRKAQgEGQRVLVHCQMGMSRSSALAILWMMDFHDMTLKQAYDYVHSKRP .. ..|.| | . | . | | | .. ||| |. | | ... ...| ..| . | |||| yfynfglkDygvasleriL-divkvvdfal-eegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrp |
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| Phosphatase | mbre_MKP_25952.AA | Subfamily.R_Nematode_3.PD | 285-316 | 45 | 9.2e-06 | 15.9 | In-house | 189-217 (267) | Show / Hide |
Range on Protein: 285-316 Range on HMM: 189-217/267 Sequence Identity: 45% (14 aa) DFIAFVRKAQgegQRVLVHCQMGMSRSSALAI . | ||.| . . |.||| |.||| .|| elikfveksk---tpvvVHCsdGisRsatlaa |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| mbre_MKP_25952.AA | Protein | None | 396 | None | Fasta, JSON |
| mbre_MKP_25952.NA | RNA | None | 1188 | None | Fasta, JSON |
| mbre_MKP_25952.AA.PD2_218-357 | Protein Phosphatase Domain | None | 140 | None | Fasta, JSON |