Gene mbre_PTPDC1B
mbre_PTPDC1B
Species: M.brevicollis
Alias: mbre_PTPDC1B
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of mbre_PTPDC1B.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| PH | mbre_PTPDC1B.AA | PH | 56-154 | 23 | 3.5e-13 | 51.04 | SMART | 1-82 (82) | Show / Hide |
Range on Protein: 56-154 Range on HMM: 1-82/82 Sequence Identity: 23% (23 aa) SDQEGHLLKRGKNTNSAWRRRYLILFDSMIEYRRSQRDADPAGTIQLKGARLNISKTPDPSMDLLEISSPSQARMYLLQGG-PLLIREWAQAIRQQIALL ||.|.|.. . |..|...||.... | .. .| |.| |...... . .||.. .. |..| . .|| |||.. |. . VIKEGWLYKKS---K-RWKKRWFVLFNDCLYYYKDK---KPKGSIPLSDCTVRE-P-------CFEIHH-DR--TYYFQCESEEEMQEWMQAIQKAIHNN |
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| Phosphatase | mbre_PTPDC1B.AA | Family.DSP.PD | 331-517 | 19 | 2.1e-15 | 48.2 | In-house | 59-215 (387) | Show / Hide |
Range on Protein: 331-517
Range on HMM: 59-215/387
Sequence Identity: 19% (33 aa)
PSQRDVSAKNSKLGDIVRKLASSERMCKMFCGGAGCQYCG-DLERWLHNDQAIPgifstwitndILALARPTQRgvDEfglLDKLVESRVRVLINLEdhg
.|. |.|| .. |...... . .. .. ..|. .. . .| | |... . . |..| | .| . .|||..
asyapvlaklhvryvisgakqaelngfidvhtfdldtydhfervengkpseilp----------hlylgsllaa--kn---lewlkelgvtkivnlt---
ehancgqgnlpgG----FSYdldafaARGVAVHLFGWADYGVPSMQT-ALTMVKVAAQALDLQVAVAVHCHAGLGRTGMLIACILVYVLKLVY
|.... ... |...|... ... .. | . |.|||.||.||.|.||.. |.. .|.
------------ddkpqftk------elgikylripidDhnapplenlfekaidfieegndskgvVlVHCkaGkgRsgtliiaYlmksegltl
|
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| PH | mbre_PTPDC1B.AA | PH | 56-152 | 20 | 2.2e-09 | 36.47 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 56-152 Range on HMM: 1-92/92 Sequence Identity: 20% (20 aa) SDQEGHLLKRGKNTNSAWRRRYLILFDSMIEYRRSQRDADPAGTIQLKGARLNISKTPDPSMDLLEISSPSQARMYLLQGGPLLIREWAQAIRQQIA ||.|.|.| .. |..|...||.. . | .. ..| |.| |..... . ... . ..|.. .. . |. . ..| |||.. .. VIKEGWLHKKG--KRKSWKKRWFVLFNNCLYYYKDDK-YRPKGSIPLSDCQVTKVPDN-KRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.PTPDC1.PD | 333-515 | 45 | 3.2e-68 | 220.8 | In-house | 14-194 (229) | Show / Hide |
Range on Protein: 333-515 Range on HMM: 14-194/229 Sequence Identity: 45% (83 aa) QRDVSAKNSKLGDIVRKLASSERMCKMFCGGAGCQYCGdLERWLHNDQAIPGIFSTWITNDILALARPTQRGVDEFGLLDKLVESRVRVLINLEDHGEHA .. ||. ||. . .|.|.|..| ||.||.|..|.|. . .. .|. |..|||.|..|||||||.. .|.. ||.|. || .. .||| . |||| ekkasaryskvseklrsltsesrkcklfckgrkckysd-vrarkeetlaadglystwvtenilalarpsselldqykllekfkesGikavinLqeageha NCGQGNLPGGFSYDLDAFAARGVAVHLFGWADYGVPSMQTALTMVKVAAQALdLQVAVAVHCHAGLGRTGMLIACILVYVLKL ||.|. ||||| ... .|.... ||..||||.|....|..|||...|| .....||||||||||||.||||.|||..| hCGagleesGfsYdpeelmrqgiyfynfglkDygvasleriLdivkvvdfal-eegkiavHCHAGlGRtGvliacylvyakrl |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.CDC14.PD | 369-515 | 28 | 2.6e-13 | 41.5 | In-house | 90-226 (258) | Show / Hide |
Range on Protein: 369-515 Range on HMM: 90-226/258 Sequence Identity: 28% (44 aa) CGDLERWLHNDQAIPGIFSTWITNDILALARPTQRGVDEFG--------LLDKLVESRVRVLINLEDHgehancgqgnlpggfSYDLDAFAARGVAVHLF . ||. . | .. | |.| | | ..||| | .. | | ||. . |. .. | . || |. |.| . tfdldtydhfervengdfttiipnkfialagphnkskvedGytllaPeklleyfrknnvttivrLnkk---------------lYdakkftdaGfahlDl GWADYGVPSMQTALTMVKVAAQAldlQVAVAVHCHAGLGRTGMLIACILVYVLKL ..| .||| . .... .| . |.||||.|||||||.||.| |.. .. ffiDGtvPsdailkkfleiteka---eGaiavhCkaGLGrtgtligcylikhyrf |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.DSP23.PD | 451-514 | 34 | 4.6e-12 | 37.4 | In-house | 30-93 (128) | Show / Hide |
Range on Protein: 451-514 Range on HMM: 30-93/128 Sequence Identity: 34% (22 aa) AARGVAVHLFGWADYGVPSMQTALTMVKVAAQALDLQVAVAVHCHAGLGRTGMLIACILVYVLK || ..... . |. |... .|.. .| . . ||.||| |||||| |.|| || . aapsltlrridipdfcPPaleqvarlvriveeaekkeeavgvhcalGlGrtGtllacylvkeeg |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.N13.PD | 458-510 | 33 | 2.1e-09 | 28.5 | In-house | 161-214 (259) | Show / Hide |
Range on Protein: 458-510 Range on HMM: 161-214/259 Sequence Identity: 33% (18 aa) HLFGWADYGVPSMQTA-LTMVKVAAQALDLQVAVAVHCHAGLGRTGMLIACILV .. | |.|||| . ...|. .. . . ..||| ||.||.|.||. | nfvkwPdhgvPssaaelvqfvaevrllqtdagPivvhcsaGiGrsGvlitidvv |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.RB.PD | 457-507 | 38 | 3.6e-09 | 27.7 | In-house | 159-213 (261) | Show / Hide |
Range on Protein: 457-507 Range on HMM: 159-213/261 Sequence Identity: 38% (21 aa) VHLFGWADYGVPSM-QTALTMVKVAAQALD---LQVAVAVHCHAGLGRTGMLIAC .| |.|.|||. .| | .|. .|.. . . ||| ||.|||| || yhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHCsaGvGRtGtfial |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.PRL.PD | 444-510 | 30 | 8e-09 | 26.7 | In-house | 36-104 (140) | Show / Hide |
Range on Protein: 444-510 Range on HMM: 36-104/140 Sequence Identity: 30% (21 aa) SYDLDAFAARGVAVHLFGWADYGVPSMQTALTMVKVAAQAL--DLQVAVAVHCHAGLGRTGMLIACILV ||| . . ..|. |. . ..| .||. . ... .. . . .||||| |||||. .|.| |. sydaeklkeegievldlafddGavPpkevvdeWlellkekfkeepkstvavhcvaGlGraPvlvalali |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.N_Nematode_1.PD | 458-510 | 30 | 1e-08 | 26.1 | In-house | 169-219 (265) | Show / Hide |
Range on Protein: 458-510 Range on HMM: 169-219/265 Sequence Identity: 30% (16 aa) HLFGWADYGVPSMQtaLTMVKVAAQALDLQVAVAVHCHAGLGRTGMLIACILV . | | |||... |..... ... .. ..||| ||.|||| ..| .. qWtdWPdrGvPpad--laalelleavrgskgPivvhCsaGiGrtGtivaieyi |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.N12.PD | 458-510 | 36 | 1.1e-08 | 25.8 | In-house | 168-222 (270) | Show / Hide |
Range on Protein: 458-510 Range on HMM: 168-222/270 Sequence Identity: 36% (20 aa) HLFGWADYGVPSMQT-ALTMVKVAAQAL-DLQVAVAVHCHAGLGRTGMLIACILV | | | |||| .. | ... . . . .. ..||| || |||| .|| .| hytaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyv |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.PTEN.PD | 457-514 | 31 | 1.9e-08 | 25.2 | In-house | 62-121 (305) | Show / Hide |
Range on Protein: 457-514 Range on HMM: 62-121/305 Sequence Identity: 31% (19 aa) VHLFGWADYGVPSMQTALTMVKVAAQAL--DLQVAVAVHCHAGLGRTGMLIACILVYVLK |. .. | |... ..|. . | | . |||||.|| ||||..|.. |.. .. vavypfdDhnpptleLleeivedvdkwLkedksnVvavHCkaGkGRtGvmicayLlksgi |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.RA.PD | 457-507 | 32 | 2.5e-08 | 24.8 | In-house | 165-218 (266) | Show / Hide |
Range on Protein: 457-507 Range on HMM: 165-218/266 Sequence Identity: 32% (17 aa) VHLFGWADYGVPSMQTALTMVKVAAQALDLQV---AVAVHCHAGLGRTGMLIAC .|. .| . |||. . . . ..|. | ...||| || |||| .|. fhftswpevGvpaegkGmlkllkkvkklqqqsanhpivvhcsaGvGrtGtfivl |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.R_Anemone_1.PD | 457-506 | 40 | 4.6e-08 | 24.3 | In-house | 158-209 (258) | Show / Hide |
Range on Protein: 457-506 Range on HMM: 158-209/258 Sequence Identity: 40% (21 aa) VHLFGWADYGVPSMQTALT--MVKVAAQALDLQVAVAVHCHAGLGRTGMLIA .| . |.| |||. .||. . || .. | . .| ||| ||.|||| .. yhftvWpdkgvPqyatavLglrrkvqksslagarpvvvhCsaGvgRtGaflv |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.N_Nematode_6.PD | 457-519 | 39 | 1.4e-07 | 22.5 | In-house | 157-216 (253) | Show / Hide |
Range on Protein: 457-519 Range on HMM: 157-216/253 Sequence Identity: 39% (25 aa) VHLFGWADYGVP-SMQTALTMVKVAAQAldlQVAVAVHCHAGLGRTGMLiACILVYVLKLVYPR .| | |.||| |...|| ...| . . . ||| ||.|||| | | ||. . | |. ihWanWPdhGvPdsflsalrllsvvkkd---kkPivvhCsaGvGrtGtl-aliliilealrlpd |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.RK.PD | 457-510 | 31 | 1.4e-07 | 22.2 | In-house | 165-222 (267) | Show / Hide |
Range on Protein: 457-510 Range on HMM: 165-222/267 Sequence Identity: 31% (18 aa) VHLFGWADY-GVPSMQTALTM-V-KVAAQALD-LQVAVAVHCHAGLGRTGMLIACILV .. ||..| .|| ...| . .| .. . . . ||| || ||.|. ||. | fqflgWpeyrdvPvskrsllklirrvkksqeeeeeGrivvhClaGaGrsGtfiaidiv |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.N_Choan_1.PD | 459-506 | 35 | 1.7e-07 | 22.2 | In-house | 162-212 (262) | Show / Hide |
Range on Protein: 459-506 Range on HMM: 162-212/262 Sequence Identity: 35% (17 aa) LFGWADYGVPSMQTALTMVKVAA---QALDLQVAVAVHCHAGLGRTGMLIA | | |||. ..| . | . . .... .|| || |||| || ytaWPdhGvPattkellefrkavlkatkkktkaplvihCsaGvGrtGtyia |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.PTPMT1.PD | 449-515 | 28 | 2.3e-07 | 22.0 | In-house | 47-114 (146) | Show / Hide |
Range on Protein: 449-515 Range on HMM: 47-114/146 Sequence Identity: 28% (19 aa) AFAARGVAVHLFGWADYGV-PSMQTALTMVKVAAQALDLQVAVAVHCHAGLGRTGMLIACILVYVLKL . . || . |.. ||... |.. . ... .| ||| || .| . |.|| |.. || ewkklGveqlqlatvDfteapslekleegvefiekvaskgssvYvHCkAGrtRsatlvacylmkkkkl |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.N3.PD | 459-507 | 42 | 3.4e-07 | 21.0 | In-house | 163-213 (261) | Show / Hide |
Range on Protein: 459-507 Range on HMM: 163-213/261 Sequence Identity: 42% (20 aa) LFGWADYGVPSMQTA-LTMVK-VAAQALDLQVAVAVHCHAGLGRTGMLIAC |.| |||. .. |..|. | . . | ||| ||.||||.||. ylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlill |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.R_Nematode_3.PD | 459-511 | 24 | 4.4e-07 | 20.8 | In-house | 172-222 (267) | Show / Hide |
Range on Protein: 459-511 Range on HMM: 172-222/267 Sequence Identity: 24% (13 aa) LFGWADYGVPsmQTALTMVKVAAQALDLQVAVAVHCHAGLGRTGMLIACILVY . || . ..| ... ...... . . | |||..| .|.. | | .|.| ykgWkelnap--eepkealelikfveksktpvvVHCsdGisRsatlaaielgy |
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| Phosphatase | mbre_PTPDC1B.AA | Y_phosphatase | 458-506 | 33 | 9.4e-07 | 24.83 | Pfam | 143-197 (243) | Show / Hide |
Range on Protein: 458-506 Range on HMM: 143-197/243 Sequence Identity: 33% (19 aa) HLFGWADYGVPSMQTALTMVKVAAQALDLQV-------AVAVHCHAGLGRTGMLIA | .| |.|||.. .. |... | | . ||| || |||| ..| HYTNWPDHGVPES-QPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCA |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.R_Anemone_2.PD | 458-507 | 38 | 1.3e-06 | 19.4 | In-house | 162-214 (262) | Show / Hide |
Range on Protein: 458-507 Range on HMM: 162-214/262 Sequence Identity: 38% (20 aa) HLFGWADYGVPSMQTAL-TMVKVAAQA--LDLQVAVAVHCHAGLGRTGMLIAC | |.| |||. . | .|. . .| . ...||| ||.||||. || hytsWpdegvpesgaslldlvrqvekaqqesgagpivvhcsaGvGrtGvfiav |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.N6.PD | 457-507 | 34 | 2.3e-06 | 18.4 | In-house | 190-244 (295) | Show / Hide |
Range on Protein: 457-507 Range on HMM: 190-244/295 Sequence Identity: 34% (18 aa) VHLFGWADYGVPSMQTAL----TMVKVAAQALDLQVAVAVHCHAGLGRTGMLIAC | | | |||. . .. . |. ...| . .. ||| ||.|||| .| yhfkaWPdhgvpkdpgvvlnfledvnkkqeelekagpivvhcsaGiGrtGtfivi |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.RNGTT.PD | 487-532 | 34 | 2.8e-06 | 18.3 | In-house | 79-119 (140) | Show / Hide |
Range on Protein: 487-532 Range on HMM: 79-119/140 Sequence Identity: 34% (16 aa) QVAVAVHCHAGLGRTGMLIACILVYVLKLvyprtCVEGCVEHFAHT . ..||| | |||.||.. || ... || |. ||.. devigvhCthGfnrtGflivayLvekedw-----sveaavalfaka |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.R_Sponge_2.PD | 458-507 | 36 | 2.9e-06 | 18.2 | In-house | 162-214 (262) | Show / Hide |
Range on Protein: 458-507 Range on HMM: 162-214/262 Sequence Identity: 36% (19 aa) HLFGWADYGVPSMQTAL-TMVKV--AAQALDLQVAVAVHCHAGLGRTGMLIAC | |.. .||. .|.| ..| || . ..|. |.| .|.|||| || hfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsdgvgrtGtfial |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.TPIP.PD | 464-512 | 32 | 5.9e-06 | 17.3 | In-house | 12-62 (245) | Show / Hide |
Range on Protein: 464-512 Range on HMM: 12-62/245 Sequence Identity: 32% (16 aa) DYGVPSMQTALTMVKVAAQA--LDLQVAVAVHCHAGLGRTGMLIACILVYV |. || .. ... | . . ||. ||.|| | |||| .. ..|.. dhnvPtleelvvftkevkewlakdlenvvaihckGGkgrtGtivcallias |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.N5_RR.PD | 461-508 | 38 | 1e-05 | 16.3 | In-house | 166-218 (265) | Show / Hide |
Range on Protein: 461-508 Range on HMM: 166-218/265 Sequence Identity: 38% (19 aa) GWADYGVPSMQ-TALTMV-KV--AAQALDLQ-VAVAVHCHAGLGRTGMLIACI | | .| | | .| .| .... . . | ||| ||.||||. || dWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiais |
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| Phosphatase | mbre_PTPDC1B.AA | Subfamily.N_Choan_2.PD | 462-507 | 38 | 1e-05 | 16.1 | In-house | 163-218 (266) | Show / Hide |
Range on Protein: 462-507 Range on HMM: 163-218/266 Sequence Identity: 38% (21 aa) WADYGVPSMQT----------ALTMVKVAAQALDLQVAVAVHCHAGLGRTGMLIAC | | |||... | |. . || . . ||| ||.||||.||| WpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtliai |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| mbre_PTPDC1B.AA | Protein | None | 1171 | None | Fasta, JSON |
| mbre_PTPDC1B.NA | RNA | None | 3513 | None | Fasta, JSON |
| mbre_PTPDC1B.AA.PD_453-536 | Protein Phosphatase Domain | None | 84 | None | Fasta, JSON |