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Gene mbre_RNGTT

mbre_RNGTT
Species: M.brevicollis
Alias: mbre_RNGTT
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: RNGTT
Protein domain

Protein domains of mbre_RNGTT.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase mbre_RNGTT.AA Subfamily.RNGTT.PD 49-187 47 1.8e-64 206.2 In-house 2-139 (140) Show / Hide 
Range on Protein: 49-187
Range on HMM: 2-139/140
Sequence Identity: 47% (68 aa)

ERAWTPEMAKA---RYKDELRFVINLTKTTRYYEAEEFGND-VHTQQIQCAGHGERPTPEQVKVFIHVCKTFWQKQPGCTIGVHCTHGFNRTGFMICCYL
|.|..|||.|.   ..|..|..||.||.|.|||..||.... |.....||.|.||.||.||.|.||...|.|..|.|...||||||||||||||.|..||
eeafepemlksylktlkvklglvidltntsryydkeelekegvkyiklqcrGrGeaPtkeqtklfiklvkeflkkkPdevigvhCthGfnrtGflivayL

IEEMDCAVEDALQLFAKSRDPGIYKYGkatffFFFSFFQLRPS
.|..|..||.|..||||.|.|||||..     .....|.....
vekedwsveaavalfakarppGiyked-----ylkelfkryed
MRNA_cap_enzyme mbre_RNGTT.AA mRNA_cap_enzyme 389-585 31 1.2e-70 168.74 Pfam 1-213 (213) Show / Hide 
Range on Protein: 389-585
Range on HMM: 1-213/213
Sequence Identity: 31% (68 aa)

QPVSLNR-DSLLDLSRADYMISWKSDGTRYLMLLADQ-------KVYFVGRDNNYFCVAGKVRFPNQD------LKSVHQNTLLDGEMVYDCWKDPATKK
||||. | . .  |. ..|. .||.||.||.|...|         .|.. ||.||. |  ..|||.        |. .|..|||||||. |  ..  |..
QPVSMSRRENMKFLKQNYYYVCWKTDGMRYMMFITDHPEYGEFKGCYMIDRDMNYYHVE-NMRFPCKYNKWGESLDKHHHYTLLDGEMCIDTIPMQETQC

KQYRARFYIFDMIACNGES-FRHKPYN--ERLEAVQTHILNPRLKQSTWPGYKEKYAQEPFSVRLKPFLPLADFQSDQ----WRKMRSQVQHKDDGLLLV
.|.  |..|.|..|.||..  .  | .  .|.|.  . |..||..       . .|...|||||.|.....   .|.       |    . |. ||| ..
QQP--RYLIYDCVAINGQCRVMQWPFYSRKRWEMIKREIIKPRNHNMKFKTHWYRYDMFPFSVRFKDMWDN--WHSEKLVYYFHKFIPHLCHEIDGLIFQ

RVAHEYKAGSCKALLKWK
 .   |..| |. |.|||
CWDTPYVPGRCQNLFKWK
Phosphatase mbre_RNGTT.AA Subfamily.DSP11.PD 62-164 44 4.8e-30 94.7 In-house 19-123 (141) Show / Hide 
Range on Protein: 62-164
Range on HMM: 19-123/141
Sequence Identity: 44% (45 aa)

KDELRFVINLTKTTRYYEAEEFGND-VHTQQIQCAGHgERPTPEQVKVFIHVCKTFW--QKQPGCTIGVHCTHGFNRTGFMICCYLIEEMDCAVEDALQL
. .| .||.||.|.|||. .|. .  |. ....|.|| | |  |.|| |... | |   .|. .  |||||||| ||||..|| |||. ..|||.. | .
nkklGLvidltntdryykkkeltdegvkykklncpGh-evpekedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyspedaiea

FAKSRD
 |    
feearG
Phosphatase mbre_RNGTT.AA Family.DSP.PD 67-170 23 1.2e-20 64.6 In-house 135-232 (387) Show / Hide 
Range on Protein: 67-170
Range on HMM: 135-232/387
Sequence Identity: 23% (24 aa)

FVINLTKTTRYyeaEEFGNDVHTQQIQCAGHgERPTPEQVkvFIHVCKtFWQK--QPGCTIGVHCTHGFNRTGFMICCYLIEEMDCAVEDALQLFAKSRd
..|||.       ... ....  .|..  | ..|..|..  |. ... | ..  ... .. |||..| .|.| .|..||.. ...  |.||..... | |
kivnltddkpq---ftkelgikylripidDh-napplenl--fekaid-fieegndskgvVlVHCkaGkgRsgtliiaYlmksegltleealdwvrskR-

PGIYKY
|. .  
pgvitp
Phosphatase mbre_RNGTT.AA Subfamily.DSP23.PD 64-166 28 2.9e-16 50.2 In-house 13-110 (128) Show / Hide 
Range on Protein: 64-166
Range on HMM: 13-110/128
Sequence Identity: 28% (28 aa)

ELRFVINLTKTTRYYeaEEFGNDVHTQQIQCAGHgERPTPEQVKVFIHVCKTFWQKQpgCTIGVHCTHGFNRTGFMICCYLIEEMDCAVEDALQLFAKSR
.|....||. .. |  .|  ...  ..|.   .   |..|||. ......   .|.   ..||||  |. ||| .. |||..| . | .||.    | | 
Girvlvslttegapy--seaapsltlrridipdf-cPPaleqvarlvriveeaekke--eavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrr

DPG
   
kGs
Phosphatase mbre_RNGTT.AA Subfamily.PTEN.PD 60-163 24 3.5e-12 36.8 In-house 37-136 (305) Show / Hide 
Range on Protein: 60-163
Range on HMM: 37-136/305
Sequence Identity: 24% (25 aa)

RYKDELRFVInlTKTTRYYEAEEFGNDVHTQQIQcaGHgERPTPEQVKVFIHVCKTFWQKQPGCTIGVHCTHGFNRTGFMICCYLIEEMDCAVE-DALQL
.||.. .. |   .. . .|  .| . |..  ..   |   || | .. ...  ... ...    . |||  |  ||| |||.||.... .. .||....
vykgkgklri--lnargekedsdfdgrvavypfd--Dh-npptleLleeivedvdkwLkedksnVvavHCkaGkGRtGvmicayLlksgikksadealai

FAKSR
. |  
ydekR
Phosphatase mbre_RNGTT.AA Subfamily.PRL.PD 76-164 25 7.1e-12 35.8 In-house 35-122 (140) Show / Hide 
Range on Protein: 76-164
Range on HMM: 35-122/140
Sequence Identity: 25% (22 aa)

RYYEAEEF-GNDVHTQQIQCAgHGERPTPEQVKVFIHVCKTFWQKQPGCTIGVHCTHGFNRTGFMICCYLIEEmDCAVEDALQLFAKSRD
|.||..  .... .... .  |  |. | |. .....|. ....|..|..|||  |. |.  ...  |||.     |||...  . |   
psydaeklkeegievldlafd-dGavPpkevvdeWlellkekfkeepkstvavhcvaGlGraPvlvalaliea-Gmkyedavefirekrr
Phosphatase mbre_RNGTT.AA Subfamily.CDC14.PD 63-156 23 2e-10 31.2 In-house 146-232 (258) Show / Hide 
Range on Protein: 63-156
Range on HMM: 146-232/258
Sequence Identity: 23% (22 aa)

DELRFVINLTKTtrYYEAEEFGNDVHTQQIQCAGHGERPTPEQVKVFIHVCKTFwqkqpGCTIGVHCTHGFNRTGFMICCYLIEEMDCAVEDAL
... .. | |    |.|..| .     . .    |  |... .| |.... .        .| |||  |  ||| .| |||| .   . .... 
nnvttivrLnkk--lYdakkftdaGfahlDlffiDGtvPsdailkkfleiteka-----eGaiavhCkaGLGrtgtligcylikhyrftaaeti
Phosphatase mbre_RNGTT.AA Subfamily.PTPDC1.PD 118-173 30 1.7e-09 27.9 In-house 162-217 (229) Show / Hide 
Range on Protein: 118-173
Range on HMM: 162-217/229
Sequence Identity: 30% (17 aa)

QKQPGCTIGVHCTHGFNRTGFMICCYLIEEMDCAVEDALQLFAKSRDPGIYKYGKA
.      |.|||  |  ||| .|.|||.   . . |.|..|  . |   |.  .. 
faleegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrpksiqtreqv
Phosphatase mbre_RNGTT.AA Subfamily.TPIP.PD 92-163 31 2.2e-09 27.7 In-house 8-79 (245) Show / Hide 
Range on Protein: 92-163
Range on HMM: 8-79/245
Sequence Identity: 31% (23 aa)

IQCAGHgERPTPEQVKVFIHVCKTFWQKQPGCTIGVHCTHGFNRTGFMICCYLIE-EMDCAVEDALQLFAKSR
|.   | . || |.. || .  | . .| .   . .||  | .||| ..|..||. |.    |..|. |.. |
imiddh-nvPtleelvvftkevkewlakdlenvvaihckGGkgrtGtivcalliaseifltaeesldyfgerr
Phosphatase mbre_RNGTT.AA Subfamily.PTPMT1.PD 87-164 24 4e-08 23.7 In-house 53-128 (146) Show / Hide 
Range on Protein: 87-164
Range on HMM: 53-128/146
Sequence Identity: 24% (19 aa)

VHTQQIQCAGHGERPTPEQVKVFIHVCKTFWQKqpGCTIGVHCTHGFNRTGFMICCYLIEEMDCAVEDALQLFAKSRD
|.  |.    ..| |. |...  ... ... .|  | .. |||  |  | . .. |||...  .. |.| ....| |.
veqlqlatvDfteapslekleegvefiekvask--gssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRp
Phosphatase mbre_RNGTT.AA DSPc 104-168 24 1e-07 28.74 Pfam 72-136 (151) Show / Hide 
Range on Protein: 104-168
Range on HMM: 72-136/151
Sequence Identity: 24% (17 aa)

EQVKVFIHVCKTFWQKQPGCTIGVHCTHGFNRTGFMICCYLIEEMDCAVEDALQLF----AKSRD-PGIY
.... ||. |     .| |. . |||..| .|.. ....||.  . . ...|. ..     |.|  |.|.
PMATDFIDDC-----RQKGGKVLVHCQAGISRSACLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMIS
Phosphatase mbre_RNGTT.AA Subfamily.DSP12.PD 122-163 26 6e-06 16.9 In-house 81-122 (143) Show / Hide 
Range on Protein: 122-163
Range on HMM: 81-122/143
Sequence Identity: 26% (11 aa)

GCTIGVHCTHGFNRTGFMICCYLIEEMDCAVEDALQLFAKSR
. .. |||. |  |   ..  ||. . .. .|.||.|  . .
egavlvHClagvSRSvtiviAYlmkkeklslekAlklvkekk
Phosphatase mbre_RNGTT.AA Subfamily.DSP10.PD 65-163 16 9.6e-06 16.0 In-house 28-122 (141) Show / Hide 
Range on Protein: 65-163
Range on HMM: 28-122/141
Sequence Identity: 16% (16 aa)

LRFVINLTKTTRYYEAEEfgNDVHTQQIQCAGHGERPTPEQVKVFIHVCKTFwqKQPGCTIGVHCTHGFNRTGFMICCYLIEEMDCAVEDALQLFAKSR
...|.|.|...  .  |.  ..|. ..|.    |..   .. .  ..  .    .. | .. |||. |  |.  ..  |... .. ....|..  . | 
ikyvlnvttsvPnffeek--glvrykripvsdsgkqnlkqkfeealefieea--rkrgsrvlvhchaGisrsatvviayvmkhlslslseaykfvkekr
MRNA_cap_C mbre_RNGTT.AA mRNA_cap_C 648-700 39 4.7e-13 48.16 Pfam 81-138 (138) Show / Hide 
Range on Protein: 648-700
Range on HMM: 81-138/138
Sequence Identity: 39% (23 aa)

YDGKIVECNWLSDL---NR--WNILLERKDKTHPNAFHTAINVVGSIRDGIELRELED
|..||||| || |    .|  |  . .|.||. || . || .|. || |..   .| .
YNNKIVECTWLVDNKQKGRPEWVFMRFRTDKSNPNHINTARKVCYSIEDNVTKEYLFE
Sequence
Name Sequence Type Origin Length Description Download
mbre_RNGTT.AA Protein None 735 None Fasta, JSON
mbre_RNGTT.NA RNA None 2205 None Fasta, JSON
mbre_RNGTT.AA.PD_47-196 Protein Phosphatase Domain None 150 None Fasta, JSON