• Phosphatome.Net

Gene mbre_SSH-B

mbre_SSH-B
Species: M.brevicollis
Alias: mbre_SSH-B
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: Slingshot
Protein domain

Protein domains of mbre_SSH-B.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
DEK_C mbre_SSH-B.AA DEK_C 287-340 32 7.6e-14 49.29 Pfam 1-56 (56) Show / Hide 
Range on Protein: 287-340
Range on HMM: 1-56/56
Sequence Identity: 32% (18 aa)

WRRLLLPEIKKIIAASDLDTLTSKEVRLALELKF-GRTLK-QFKGYIDEQMIVAFG
 .. .  ||..| . .||.|.|.|..| .|| .| |  |. ..| .|.||. . ..
TDEQIKEEIREILRTADLMTVTMKQIRKQLEQRFPGCDLSKHRKAFIKEQIEEFLD
Phosphatase mbre_SSH-B.AA Subfamily.Slingshot.PD 345-477 56 1.4e-67 216.4 In-house 2-134 (139) Show / Hide 
Range on Protein: 345-477
Range on HMM: 2-134/139
Sequence Identity: 56% (75 aa)

PSPISDLIFLGTEWNACNLEELRENGCSHILNVTEEVPSYFEQDFEYLRISLPDEETENLLQHWNRTFDFIELARANDSRVLVHCKMGVSRSASTVMAYL
.| |.| ..||.||||.|||||.|||...|||||.|. ..|...|.||.|.. |||...||.|||.|..||| |....|.||||||||||||||||.|| 
askifdhlylGsewnasnleelkengveyilnvtkeidnffpekfkylnirvydeeetdllkhwnetykfiekakekgskvlvhckmGvsrsastviaya

MRFHGWTRDHTFEYVRERRNVVQPNKGFWEQLK
|. .........|||.|||....|||||..|||
mkeyelsleealeyvkerrsiikpnkgflkqlk
Phosphatase mbre_SSH-B.AA Subfamily.DSP19.PD 348-477 44 8.3e-42 133.0 In-house 5-134 (139) Show / Hide 
Range on Protein: 348-477
Range on HMM: 5-134/139
Sequence Identity: 44% (57 aa)

ISDLIFLGTEWNACNLEELRENGCSHILNVTEEVPSYFEQDFEYLRISLPDEETENLLQHWNRTFDFIELARANDSRVLVHCKMGVSRSASTVMAYLMRF
... ..||    | ..|.|....  |||||. .||  | .||.|. |.. |.. ..||.......|||| || .| ||||||. ||||||||.||||. .
vkprlylgsqdvaadkeilkklkitHilnvavgvpnvfpkdftyksieilDlpetkllsylkealdFieearskdgrvlvHCnAGvSRsasvviaylmkd

HGWTRDHTFEYVRERRNVVQPNKGFWEQLK
  .  ...|.||| |  ..||.||..||| 
eelslekalekvrearpcikPneGFikqLk
Phosphatase mbre_SSH-B.AA Subfamily.DSP1.PD 345-476 38 1.7e-40 128.9 In-house 2-133 (139) Show / Hide 
Range on Protein: 345-476
Range on HMM: 2-133/139
Sequence Identity: 38% (51 aa)

PSPISDLIFLGTEWNACNLEELRENGCSHILNVTEEVPSYFEQDFEYLRISLPDEETENLLQHWNRTFDFIELARANDSRVLVHCKMGVSRSASTVMAYL
|. | | ..||.. .| ||. |.| . ...|||..|.| .||. |.| .| . |...........   |||. ..... ||||||..|.||||. |.|||
pveildfLyLGsaehasnlqlLkelkitallnvsaelpnvfeelfkyksipvednkkadisslfeeaidfidsvkkkgGrvlvhCqaGisrsativlayL

MRFHGWTRDHTFEYVRERRNVVQPNKGFWEQL
|. . .. .. ||.|..||....|| || .||
mkekkvrleeafefvkqrrsiisPnfgfvgqL
Phosphatase mbre_SSH-B.AA Family.DSP.PD 340-477 37 3.9e-39 125.6 In-house 102-241 (387) Show / Hide 
Range on Protein: 340-477
Range on HMM: 102-241/387
Sequence Identity: 37% (52 aa)

GQMAPPSPISDLIFLGTEWNACNLEELRENGCSHILNVTEEVPSYFE-QDFEYLRISLPDEETENLLQHWNRTFDFIELARANDSRVLVHCKMGVSRSAS
.  .|| | . ..||.  .| |||.|.|.| ..|.|.|.. |.. . ....||||...| ....| ... . .|||| .. . ..||||||.|..||.. 
vengkpseilphlylgsllaaknlewlkelgvtkivnltddkpqftkelgikylripidDhnapplenlfekaidfieegndskgvVlVHCkaGkgRsgt

TVMAYLMRFHGWTRDHTFEYVRERRN-VVQPNKGFWEQLK
..|||| ..|.| . ....||..|. |..||.||..||| 
liiaYlmksegltleealdwvrskRpgvitpnqgflkqlk
Phosphatase mbre_SSH-B.AA Subfamily.DSP14.PD 347-476 34 1e-38 123.2 In-house 4-132 (138) Show / Hide 
Range on Protein: 347-476
Range on HMM: 4-132/138
Sequence Identity: 34% (44 aa)

PISDLIFLGtEWNACNLEELRENGCSHILNVTEEVPSYFEQDFEYLRISLPDEETENLLQHWNRTFDFIELARANDSRVLVHCKMGVSRSASTVMAYLMR
|.. ..|.    | . |.|.... ..|.||| |.|.   .|.....| . |.....| .|.... | || ..... ..||||..||||||| |.||||..
eitesLyls-gaaalkkeklkkkkitlivnvttelpetkledvktvkikveDkpeaklaehfdevadkieevkkkgGktlvhCvaGvsRsAslvlaylmk

FHGWTRDHTFEYVRERRNVVQPNKGFWEQL
.  .  .....|...|....||.|||.|| 
yeklsLreayklvksaRpiirPnvGFwkql
Phosphatase mbre_SSH-B.AA Subfamily.DSP6.PD 348-476 35 9.8e-37 116.4 In-house 5-135 (141) Show / Hide 
Range on Protein: 348-476
Range on HMM: 5-135/141
Sequence Identity: 35% (46 aa)

ISDLIFLGTEWNACNLEELRENGCSHILNVTEEVPSYFEQ--DFEYLRISLPDEETENLLQHWNRTFDFIELARANDSRVLVHCKMGVSRSASTVMAYLM
| .|..||.. .|.||| |.. . ...||||...|. ||.  ...|..|.. |. ..|| ...  ...||. || ..| |||||  |||||. ..||||.
ilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkykqipiedhlsqnlakffPeaiefidearskkskvlvhclaGvsrsvtvtlaylm

RFHGWTRDHTFEYVRERRNVVQPNKGFWEQL
 .  . ......|....  . ||  | .|| 
kklalslndaydlvkkkksnisPnfnfmgql
Phosphatase mbre_SSH-B.AA Subfamily.DSP10.PD 344-476 39 3.7e-35 111.5 In-house 1-135 (141) Show / Hide 
Range on Protein: 344-476
Range on HMM: 1-135/141
Sequence Identity: 39% (53 aa)

PPSPISDLIFLGTEWNACNLEELRENGCSHILNVTEEVPSYFEQ--DFEYLRISLPDEETENLLQHWNRTFDFIELARANDSRVLVHCKMGVSRSASTVM
| |.|   ..||.| .| . . |.  | ...|||| .|| .||.  ...| || . |....|| |... ...||| || ..|||||||. |.||||  |.
passilpflllGnekdaadkdaldrlgikyvlnvttsvPnffeekglvrykripvsdsgkqnlkqkfeealefieearkrgsrvlvhchaGisrsatvvi

AYLMRFHGWTRDHTFEYVRERRNVVQPNKGFWEQL
||.|.. . .  .....|.|.| .. || .|  ||
ayvmkhlslslseaykfvkekrPiisPnlnfmGql
Phosphatase mbre_SSH-B.AA DSPc 344-477 27 7.9e-35 122.95 SMART 1-172 (172) Show / Hide 
Range on Protein: 344-477
Range on HMM: 1-172/172
Sequence Identity: 27% (48 aa)

PPSPISDLIFLGTEWNAC--NLEELRENGCSHILNVTEEVP-----------------SYFEQDFEYLRIS-LPD-------EETENLLQHWNRTFDFIE
.|| |.  ..|| .  .   |...| ...  |..|||.|.|                 .|. ..|.|..|  . |       ....|..|......|||.
GPSEITPHLYLGSYPHHMEPNPCFLKKHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFIH

LARANDSRVLVHCKMGVSRSASTVMAYLMRFHGWTRDHTFEYV-----RERR-NVVQPNKGFWEQL-----K
 .|..  .|||||..|.||||. ..||||. .... .. ...|     ..|| . ..|| .|| ||     |
DCRQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK
Phosphatase mbre_SSH-B.AA DSPc 352-477 28 1.7e-33 118.4 Pfam 1-151 (151) Show / Hide 
Range on Protein: 352-477
Range on HMM: 1-151/151
Sequence Identity: 28% (43 aa)

IFLGTEWNAC-NLEELRENGCSHILNVTEEVPS---YFEQDFEYLRIS-LPD---------EETENLLQHWNRTFDFIELARANDSRVLVHCKMGVSRSA
..|| .  .  ... | ..| .|..|.|.|.|    |   .|.|..|  . |         ....|. |. .. .|||. .|..  .|||||..|.||||
LYLGSYPHHMADPAFLQKHGITHVINCTMECPNNWFYHNSHFHYMWIPHVHDHIHYYHIHWNHCTNISQYFPMATDFIDDCRQKGGKVLVHCQAGISRSA

STVMAYLMRFHGWTRDHTFEYV-----RERR-NVVQPNKGFWEQL-----K
. ..||||. .... .. ...|     ..||  .. || .|| ||     .
CLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ
Phosphatase mbre_SSH-B.AA Subfamily.DSP12.PD 348-477 35 2.5e-33 105.8 In-house 5-136 (143) Show / Hide 
Range on Protein: 348-477
Range on HMM: 5-136/143
Sequence Identity: 35% (47 aa)

ISDLIFLGTEWNACNLEELRENGCSHILNVTEEV-PSYF-EQDFEYLRISLPDEETENLLQHWNRTFDFIELARANDSRVLVHCKMGVSRSASTVMAYLM
| . ..||.  .. . |.|.|   .|.| |..|  |..  |.. ... |.. ||..|.||.| .....||| .....  |||||..|||||...|.||||
ilpglylggleavqerellkelkithvlsvikeelpelqkekgvkskliqilDepeedlLshldeavrFieeglekegavlvHClagvSRSvtiviAYlm

RFHGWTRDHTFEYVRERRNVVQPNKGFWEQLK
. ...  .. .. |.| .. ..||.|| ||||
kkeklslekAlklvkekkkeiepNegFleQLk
Phosphatase mbre_SSH-B.AA Subfamily.DSP8.PD 348-476 33 6.5e-33 104.3 In-house 5-135 (143) Show / Hide 
Range on Protein: 348-476
Range on HMM: 5-135/143
Sequence Identity: 33% (44 aa)

ISDLIFLGTEWNACNLEELRENGCSHILNVTEEVPS--YFEQDFEYLRISLPDEETENLLQHWNRTFDFIELARANDSRVLVHCKMGVSRSASTVMAYLM
| . ..||.. .. . | |...| |..||..|. |    .... ..||| . |. .|.||........||. ||.....|||||  | ||||. ..||.|
ilpnlylGsqkdsldeellkklgisyvlnisescpkdvellkesrflriPvkDkyeekllpwfdkalefidkarsangkvlvhclaGisrsatvaiayim

RFHGWTRDHTFEYVRERRNVVQPNKGFWEQL
.    . |.....|.|.|. ..||  | .||
ktlemsldeayrfvkekrptispnlnflgqL
Phosphatase mbre_SSH-B.AA Subfamily.LRR-DSP.PD 345-477 36 1.2e-29 93.6 In-house 2-132 (137) Show / Hide 
Range on Protein: 345-477
Range on HMM: 2-132/137
Sequence Identity: 36% (48 aa)

PSPISDLIFLGTEWNACNLEELRENGCSHILNVTEEVPsYFEQDFEYLRISLPDEETENLLQHWNRTFDFIELARANdSRVLVHCKMGVSRSASTVMAYL
|. | | ..||.   | |   |..|. .||| |..  | .. . | || | . | .  .. ||....  ||.  | .   ||.||. ||||||. |.|||
pdliidklylgcresamnksilkdnnvthilavadfkp-lypdlfkyliidiedvdeadiyqhfkemnafidegrek-ggvlihcragvsrsatlviayl

MRFHGWTRDHTFEYVRERRNVVQPNKGFWEQLK
|. .  .  .... | ..|. ..||.|| .|||
mkknslkfkealdlvikkrpriypnrgfldqlk
Phosphatase mbre_SSH-B.AA Subfamily.DSP3.PD 350-476 31 1.6e-28 90.1 In-house 7-142 (148) Show / Hide 
Range on Protein: 350-476
Range on HMM: 7-142/148
Sequence Identity: 31% (43 aa)

DLIFLGTEWNACNLEELRENGCSHILNVTEE--------VPSYFEQ-DFEYLRISLPDEETENLLQHWNRTFDFIELARAN-DSRVLVHCKMGVSRSAST
. ...| |  | . |.|.. |  |.|| .|.         ...... . .|| .   |  . .| ..... .|||. | .. ...|||||..|.||||  
pkvyvgdeavakdkekLkklGithvLnaaegkrllkvdtdaefYkdleikylGvevsDvpefdlskyfeeaadfidealsqkngkvlvhcvvGisRsatl

VMAYLMRFHGWTRDHTFEYVRERRNVvQPNKGFWEQL
|.|||| ..  |  .  . ||..|.. .||.|| .||
vlayLmirrkltlkeaiktvrkkrei-lPneGflkqL
Phosphatase mbre_SSH-B.AA Subfamily.DSP15.PD 352-477 32 3.2e-27 85.8 In-house 9-133 (138) Show / Hide 
Range on Protein: 352-477
Range on HMM: 9-133/138
Sequence Identity: 32% (41 aa)

IFLGTEWNACNLEELRENGCSHILNVTEEVPSYFeQDFEYLRISLPDEETENLLQHWNRTFDFIELARANDSRVLVHCKMGVSRSASTVMAYLMRFHGWT
...|   .| . | |.||  .||| . ..    . .|..||.|.  |    .| .... . |||  .| ... |||||  |.||| . |.||.|    ..
lyvGnfrdakdkeqleenkithilsihdsakpll-edikylcikaadsPdqdlskffkesidfihkcrleggnvlvhclaGisrsvtlvvayimtvtels

RDHTFEYVRERRNVVQPNKGFWEQLK
 ..... |.  | | .|| || .||.
wedalkavkaarsvanPnvGfrrqlq
Phosphatase mbre_SSH-B.AA Subfamily.STYX.PD 353-477 35 1.7e-24 77.0 In-house 10-141 (146) Show / Hide 
Range on Protein: 353-477
Range on HMM: 10-141/146
Sequence Identity: 35% (47 aa)

FLGTEWNA--CNLEELRENGCSHILNVTEE-----VPSYFEQDFEYLRISLPDEETENLLQHWNRTFDFIELARANDSRVLVHCKMGVSRSASTVMAYLM
|||    |   .|| |.|.| .||. . ..     .   |...| || . . |. .||....  .. .||. .  .  .|||| . |.||||. |.||.|
flgpysaamksklevlkehgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaalviayim

RFHGWTRDHTFEYVRERRNVVQPNKGFWEQLK
  .|    ..| ||.||| ...||.|| .|||
etyglkyreafayvqerrfcinpnegfvsqlk
Phosphatase mbre_SSH-B.AA Subfamily.STYXL1.PD 350-477 27 8.5e-22 68.5 In-house 8-138 (143) Show / Hide 
Range on Protein: 350-477
Range on HMM: 8-138/143
Sequence Identity: 27% (36 aa)

DLIFLGTEWNACNLEELRENGCSHILNVTEEVPSYFEQD---FEYLRISLPDEETENLLQHWNRTFDFIELARANDSRVLVHCKMGVSRSASTVMAYLMR
. ..||.. .|.| .  ..      .||. .    .. .    . |.|.. ||.  .||.. ..  .|||  . ... |||  . |.||||. ..|||| 
gklylGnykqaqnpaikkdlkvkahvnvssdaekliagladvakllhiavedeneadllerlkevvqfiekhkkegevvlvfsnkGisrsaaviiaylmy

FHGWTRDHTFEYVRERRNVVQPNKGFWEQLK
 . .|  ....|... .. |.||..| |||.
skkitlkkaykylkkckenvkPnrafveqls
Phosphatase mbre_SSH-B.AA Subfamily.PTPMT1.PD 379-476 24 8.2e-17 52.0 In-house 43-140 (146) Show / Hide 
Range on Protein: 379-476
Range on HMM: 43-140/146
Sequence Identity: 24% (24 aa)

EEVPSYFEQDFEYLRISLPDEETENLLQHWNRTFDFIELARANDSRVLVHCKMGVSRSASTVMAYLMRFHGWTRDHTFEYVRERRNVVQPNKGFWEQL
...  . ..  |.|...  |      |.. ... .|||  . . |.| |||| | .|||. | .|||. . .. ..  ......|. ....  |. | 
nsteewkklGveqlqlatvDfteapslekleegvefiekvaskgssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpqirlkskqwral
Phosphatase mbre_SSH-B.AA Subfamily.DSP23.PD 366-464 28 6.7e-10 29.8 In-house 9-108 (128) Show / Hide 
Range on Protein: 366-464
Range on HMM: 9-108/128
Sequence Identity: 28% (29 aa)

LRENGCSHILNVTEEVPSYFE--QDFEYLRISLPDEETENLLQhWNRTFDFIELARANDSRVLVHCKMGVSRSASTVMAYLMRFHGWTRDHTFEYVRERR
| ..|  .....|.| ..| |  ..  . ||..||     | |  .| .  .| | ...  | ||| .|. |. . .  ||.. .| . |..   ||.||
ladqGirvlvslttegapyseaapsltlrridipdfcPPaleq-varlvriveeaekkeeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrr

N
.
k
Phosphatase mbre_SSH-B.AA Subfamily.Laforin.PD 384-465 24 1e-08 25.7 In-house 66-147 (165) Show / Hide 
Range on Protein: 384-465
Range on HMM: 66-147/165
Sequence Identity: 24% (20 aa)

YFEQDFEYLRISLPDEETENLLQHWNRTFDFIELARANDSRVLVHCKMGVSRSASTVMAYLMRFHGWTRDHTFEYVRERRNV
| |. . |. . ..|  ||. ..   ..  ..     .  .| |||. || ||.. |  .|.   ||.  .   ..  .| |
ykeeglayiwlptedlstesrvenlpqavyllhallekghivyvhcnagvgrstaivcgflqyvlgwslakvqyfllakrpv
Phosphatase mbre_SSH-B.AA Subfamily.CDC14.PD 413-463 28 1.1e-07 22.4 In-house 189-239 (258) Show / Hide 
Range on Protein: 413-463
Range on HMM: 189-239/258
Sequence Identity: 28% (14 aa)

DFIELARANDSRVLVHCKMGVSRSASTVMAYLMRFHGWTRDHTFEYVRERR
|.|..   .  . |||| |. | .. . .||.. .. | . |  ..|  | 
kfleitekaeGaiavhCkaGLGrtgtligcylikhyrftaaetiawlriar
Phosphatase mbre_SSH-B.AA Subfamily.DSP11.PD 387-463 25 9.7e-07 19.3 In-house 43-122 (141) Show / Hide 
Range on Protein: 387-463
Range on HMM: 43-122/141
Sequence Identity: 25% (20 aa)

QDFEYLRISLPDEET---ENLLQHWNRTFDFIELARANDSRVLVHCKMGVSRSASTVMAYLMRFHGWTRDHTFEYVRERR
.. .| ..  | .|.   |.. .  ..  .|.|    ||. . |||  || |.   .  ||.  .|.  ..  |   | |
egvkykklncpGhevpekedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyspedaieafeear
Phosphatase mbre_SSH-B.AA Subfamily.R_Nematode_3.PD 406-442 27 1e-06 18.9 In-house 182-218 (267) Show / Hide 
Range on Protein: 406-442
Range on HMM: 182-218/267
Sequence Identity: 27% (10 aa)

QHWNRTFDFIELARANDSRVLVHCKMGVSRSASTVMA
.. .   . |. .... . |.|||. |.||||. ...
eepkealelikfveksktpvvVHCsdGisRsatlaai
Phosphatase mbre_SSH-B.AA Subfamily.PTPDC1.PD 421-464 25 2.8e-06 17.6 In-house 165-208 (229) Show / Hide 
Range on Protein: 421-464
Range on HMM: 165-208/229
Sequence Identity: 25% (11 aa)

NDSRVLVHCKMGVSRSASTVMAYLMRFHGWTRDHTFEYVRERRN
..... |||  |  |  . . .||.  .  | ..  . ||..| 
eegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrp
Sequence
Name Sequence Type Origin Length Description Download
mbre_SSH-B.AA Protein None 477 None Fasta, JSON
mbre_SSH-B.NA RNA None 1431 None Fasta, JSON
mbre_SSH-B.AA.PD_344-477 Protein Phosphatase Domain None 134 None Fasta, JSON