Gene mbre_34638
mbre_34638
Species: M.brevicollis
Alias: mbre_34638
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of mbre_34638.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| UPF0061 | mbre_34638.AA | UPF0061 | 142-263 | 48 | 5e-44 | 149.68 | Pfam | 91-211 (631) | Show / Hide |
Range on Protein: 142-263
Range on HMM: 91-211/631
Sequence Identity: 48% (62 aa)
AHCYCGHQFGYFSGQLGDGAAMYLGE--VVNERNERWE-LQFKGAGLTPFSRQADGRKVLRSSIREFLCSEAMHALNIPTTRAGSLITSD-TRVVRDIFY
| | ||||| . .||||| .|. .. | | ||||.||.|| .||| ||||.||||| ||||| | |||||. ||...| . . ||
AQVYHGHQFGEWAPQLGDGRGFLYGQQRLKDGCTMDWHTFQLKGAGMTPYSRMGDGRAVLRSTIREFLMSEAMHYLGIPTTRCMSLVETDDSKWYRD---
TGSLIQER--ATVITRLAPSFLRFGSFE
|| . .. | |||..||| ||
----NQEPTRCAMMCRFAPSHIRFGHFE
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| UPF0061 | mbre_34638.AA | UPF0061 | 310-465 | 34 | 1.8e-50 | 171.69 | Pfam | 285-488 (631) | Show / Hide |
Range on Protein: 310-465
Range on HMM: 285-488/631
Sequence Identity: 34% (70 aa)
KFAEFLAEVTRRTAALVAQWQCVGWCHGVLNTDNMSVLGLTIDYGPFGFMEQYDPNFICNRSDDGGRYDYQSQPEICRWNLHRLADVLVPHLPLER----
|. |. | |.| |||||| .| ||||.||||||..|||.|||||||. .|.|||||| .| .||| . || .|.||| ||| | . .| .
KYREWFRHVVERNANLVAQWQAYGFCHGVMNTDNMSIMGLTFDYGPFGFLDDYEPNFICNHFDHQGRYSFDNQPAVCWWNLQRLAQDLSCFIPPDARDLE
------AR---DIIDR---------------HYTRTFEQAYMDGMRAKLGL-------LY-------PQ-----GE-DQELIKALFTVMAKTSADFTNTF
. . | . . | || .|| . . | . |. |. .||.. |..|.|
LLLKGEMNSVDEALEDTMIERVQKLVELSANEYQYVYLTHYIQIMRQRLGIDSDLEDCMDSTNLKDIEHAAEKAKEFWNKLVNQLLQCMAQEQWDYNNFF
RLLS
| |.
RHLQ
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| UPF0061 | mbre_34638.AA | UPF0061 | 585-629 | 26 | 2.8e-07 | 24.32 | Pfam | 575-631 (631) | Show / Hide |
Range on Protein: 585-629 Range on HMM: 575-631/631 Sequence Identity: 26% (15 aa) RRQVMDEHNPSFVLRNHVAQTAIA---KAEQ-G--------DFSEVQRVLEELRRPF | |.| || ||||| ...... ... | | .. .| . |. |. RQQLMQQANPLFVLRNWRIERVWQDLMYIQRDGLQDPSSELDWQPFHRLHQMLQNPY |
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| DENN | mbre_34638.AA | DENN | 711-875 | 17 | 3.3e-09 | 33.12 | SMART | 1-204 (204) | Show / Hide |
Range on Protein: 711-875 Range on HMM: 1-204/204 Sequence Identity: 17% (37 aa) RTMRCL-AFISHLPLWYQQRAALRYVYEQPV--RAQAKLLN-TILSLRVYSRL--SIYRPPLA-------------------LLQAPF----------GV .| .|. .|||.|.. | |. .|. . |. .. .. .| |. .. .. . ... |. WTPKCIHCIISHHPWFNWFRKWLNELYRYWQSDHNQHLFHHEFMIYLCHYPVPLPPPGKSIVFMSIVSYFQFHPPGNYYQPIEFCRPDDNRLPHIDENWD IDLLLQYLCPRDVVHIVLHAVLGRKIIVAGRHMTGVAHACAAIQQLMYPLSVWSVFIPNLPRHLVADV-TPIPSQYLVGIHSDDLPLADV---GD--GIV . .|...| .. .... ...| |.||. ... . . .| |. |.||.. ...|| ||.... . .| | |..|.|| ..... .. .| LHELFECLGVENIMQLFCCILLERRIIFHSSNYQMLSMCCHAFVALLYPFQWQHIYIPILPASMLDYLCAPMP--YIMGCHSSYFEEVKPEPDEEDDVVV VQLDDS | .| VDIDTN |
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| Phosphatase | mbre_34638.AA | Subfamily.MTMR1.PD | 1987-2136 | 36 | 4.5e-26 | 79.7 | In-house | 10-149 (149) | Show / Hide |
Range on Protein: 1987-2136 Range on HMM: 10-149/149 Sequence Identity: 36% (54 aa) LDTGSFWRDLDKIGWLTQVADLLHWSNVIADLCTETHAVVVIAMEHGCDAAMQLTSLAMLQLDTHYRQLDAFMAhIINRVWIQHGHPFAARAGLVAAKPS .| . .|.. || .. .| . ||| .... ||. | | . ||||||||.||..|| . | .|.. |. || ||| | . . ideskwlsaleetkwlehiklilagavriadkvesektsvvvhcsdgwdrtaqltslamllldsyyrtikgfev-liekewlsfghkfaerighgdknha prSAELSgvaglpaPTFGLFLDCVYQMLSQFPAQFEFNAELLEAIFHHSY |. | | | |.|||.|. |||. |||| |.| .|. | | --dadrs-------pvflqfidcvwqvtrqfptafefneeflitildhly |
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| DENN | mbre_34638.AA | DENN | 778-875 | 24 | 3e-06 | 23.21 | Pfam | 107-207 (207) | Show / Hide |
Range on Protein: 778-875 Range on HMM: 107-207/207 Sequence Identity: 24% (25 aa) LLLQYLCPRDVVHIVLHAVLGRKIIVAGRHMTGVAHACAAIQQLMYPLSVWSVFIPNLPRHLVADV-TPIPSQYLVGIHSDDLP----LADVGDGIVVQL .|.. | |. ..|. . ... ..|| .| . .| |. |.||.. ..|| .|..|. . .| | ...|.|| .. . | ..| | PLFRCLGPENCLHLFCCVLTEHRIIFHSSHYAMLTLCCHAVVALLYPFQWQHIYIPICPARLLDYLCAPCP--FIMGVHSRYFDSKLLYDPPDDVVCVDL DDS | DTN |
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| Phosphatase | mbre_34638.AA | Family.Myotubularin.PD | 1990-2136 | 33 | 3.1e-30 | 93.0 | In-house | 5-141 (141) | Show / Hide |
Range on Protein: 1990-2136
Range on HMM: 5-141/141
Sequence Identity: 33% (49 aa)
GSFWRDLDKIGWLTQVADLLHWSNVIADLCTETHAVVVIAMEHGCDAAMQLTSLAMLQLDTHYRQLDAFMAhIINRVWIQHGHPFAARAGLVAAKPSPRs
... .|.. || .. ||. . |.. .... |.. | | . ||||||.| ||..|| .. | .|.. |.. || || | | . | .
kkwlselestkWlehiklllkaavkivekvekektsvlvhcsdGWdrtaqltslaqllldpyyrtieGfev-liekeWlsfGhkfaerlghgdksesee-
aelsgvagLPAPTFGLFLDCVYQMLSQFPAQFEFNAELLEAIFHHSY
.| | |.|||||. ||| .||||...| | .|.|
--------ersPvflqfidcvyqltkqfptafefnesflikildhly
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| Phosphatase | mbre_34638.AA | Subfamily.MTMR3.PD | 1994-2136 | 34 | 6.9e-23 | 69.4 | In-house | 3-135 (135) | Show / Hide |
Range on Protein: 1994-2136 Range on HMM: 3-135/135 Sequence Identity: 34% (45 aa) RDLDKIGWLTQVADLLHWSNVIADLCTETHAVVVIAMEHGCDAAMQLTSLAMLQLDTHYRQLDAFMAhIINRVWIQHGHPFAARAGLVAAkpsprSAEls |.| || ... ||. . ... . |.. | | . |...|| | || .|| |. | . ...| |.. || || |.|| . .. .| | salektkwlqhlsvllkaavkvvnavdkegrpvlvhcsdgwdrtpqivalakllldpyyrtlegfkv-lverewldfghkfadrcghged-----sdd-- gvAGLPAPTFGLFLDCVYQMLSQFPAQFEFNAELLEAIFHHSY .||||.|. |||..|||| | . .|.| --lnercpvflqwldcvhqlkkqfptsfefneaflvklvqhty |
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| Phosphatase | mbre_34638.AA | Subfamily.C2-MTMR1.PD | 1993-2134 | 31 | 1.4e-22 | 68.6 | In-house | 7-135 (137) | Show / Hide |
Range on Protein: 1993-2134
Range on HMM: 7-135/137
Sequence Identity: 31% (45 aa)
WRDLDKIGWLTQVADLLHWSNVIADLCTETHAVVVIAMEHGCDAAMQLTSLAMLQLDTHYRQLDAFMAhIINRVWIQHGHPFAARAGLvAAKPSPRSael
. .|.. .||. .. .|. .. || . .. | | . ||..|| | || .|| .| .. .|.. |. || | || | .| ||
lsqlestqwlayikavlkaaraiarkveklavsalvhcsdgwdrtsqlvllaqllldpyyrtidgliv-liekewlafghkfderlgg-adsvsers---
sgvaglpaPTFGLFLDCVYQMLSQFPAQFEFNAELLEAIFHH
| | ||||.||. |||. ||..|.|| . .
--------piflqfldclyqvtkqfpsafeytarlllklady
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| mbre_34638.AA | Protein | None | 2462 | None | Fasta, JSON |
| mbre_34638.NA | RNA | None | 7386 | None | Fasta, JSON |